TreeWAS – Variant ID: rs7646507

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.5 Other deformities of toe(s) (acquired)	0.000	0.480	0.520
M20 Acquired deformities of fingers and toes	0.000	0.482	0.518
M20.1 Hallux valgus (acquired)	0.000	0.483	0.517
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.561	0.439
M20.4 Other hammer toe(s) (acquired)	0.000	0.569	0.431
M20.2 Hallux rigidus	0.000	0.576	0.424
M20.3 Other deformity of hallux (acquired)	0.000	0.608	0.392
C18.9 Colon, unspecified	0.388	0.612	0.000
C18 Malignant neoplasm of colon	0.384	0.616	0.000
C18.0 Caecum	0.365	0.635	0.000
C15-C26 Malignant neoplasms of digestive organs	0.362	0.638	0.000
C20 Malignant neoplasm of rectum	0.347	0.653	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.323	0.677	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.305	0.695	0.000
C16 Malignant neoplasm of stomach	0.302	0.698	0.000
C18.7 Sigmoid colon	0.296	0.704	0.000
C18.6 Descending colon	0.286	0.714	0.000
C18.2 Ascending colon	0.286	0.714	0.000
C18.5 Splenic flexure	0.281	0.719	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.281	0.719	0.000
M20.0 Deformity of finger(s)	0.000	0.721	0.279
C18.8 Overlapping lesion of colon	0.270	0.730	0.000
C18.4 Transverse colon	0.270	0.730	0.000
C15 Malignant neoplasm of oesophagus	0.268	0.732	0.000
C18.3 Hepatic flexure	0.267	0.733	0.000
C26.0 Intestinal tract, part unspecified	0.257	0.742	0.000
C21 Malignant neoplasm of anus and anal canal	0.254	0.746	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.253	0.747	0.000
C17 Malignant neoplasm of small intestine	0.248	0.752	0.000
C23 Malignant neoplasm of gallbladder	0.243	0.757	0.000
C16.0 Cardia	0.239	0.761	0.000
C26.9 Ill-defined sites within the digestive system	0.230	0.770	0.000
C18.1 Appendix	0.230	0.770	0.000
C16.4 Pylorus	0.228	0.772	0.000
C16.5 Lesser curvature of stomach, unspecified	0.228	0.772	0.000
C16.9 Stomach, unspecified	0.227	0.772	0.000
C16.8 Overlapping lesion of stomach	0.224	0.776	0.000
C16.1 Fundus of stomach	0.221	0.779	0.000
C26.8 Overlapping lesion of digestive system	0.219	0.781	0.000
C26.1 Spleen	0.219	0.781	0.000
C16.6 Greater curvature of stomach, unspecified	0.218	0.782	0.000
C24.9 Biliary tract, unspecified	0.216	0.784	0.000
C24.0 Extrahepatic bile duct	0.215	0.785	0.000
C15.5 Lower third of oesophagus	0.213	0.787	0.000
C16.2 Body of stomach	0.213	0.787	0.000
C15.9 Oesophagus, unspecified	0.207	0.793	0.000
C24.8 Overlapping lesion of biliary tract	0.202	0.798	0.000
C15.0 Cervical part of oesophagus	0.201	0.799	0.000
C16.3 Pyloric antrum	0.199	0.801	0.000
C24.1 Ampulla of Vater	0.196	0.804	0.000
C15.8 Overlapping lesion of oesophagus	0.192	0.808	0.000
C15.2 Abdominal part of oesophagus	0.192	0.808	0.000
C15.1 Thoracic part of oesophagus	0.191	0.809	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.184	0.815	0.000
C22.9 Liver, unspecified	0.184	0.816	0.000
C21.2 Cloacogenic zone	0.182	0.818	0.000
C22.0 Liver cell carcinoma	0.182	0.818	0.000
C22.7 Other specified carcinomas of liver	0.181	0.819	0.000
C22.4 Other sarcomas of liver	0.181	0.819	0.000
C22.3 Angiosarcoma of liver	0.181	0.819	0.000
C22.2 Hepatoblastoma	0.181	0.819	0.000
C21.0 Anus, unspecified	0.180	0.819	0.000
C17.2 Ileum	0.180	0.820	0.000
C17.8 Overlapping lesion of small intestine	0.178	0.822	0.000
C17.3 Meckel's diverticulum	0.178	0.822	0.000
C17.1 Jejunum	0.177	0.823	0.000
C21.1 Anal canal	0.176	0.824	0.000
C17.9 Small intestine, unspecified	0.172	0.828	0.000
C17.0 Duodenum	0.171	0.829	0.000
C22.1 Intrahepatic bile duct carcinoma	0.171	0.829	0.000
C15.3 Upper third of oesophagus	0.169	0.831	0.000
C15.4 Middle third of oesophagus	0.169	0.831	0.000
C25 Malignant neoplasm of pancreas	0.149	0.851	0.000
M20-M25 Other joint disorders	0.000	0.879	0.121
C25.4 Endocrine pancreas	0.111	0.888	0.000
C25.8 Overlapping lesion of pancreas	0.111	0.889	0.000
C25.7 Other parts of pancreas	0.109	0.891	0.000
M21 Other acquired deformities of limbs	0.000	0.897	0.103
C25.3 Pancreatic duct	0.102	0.898	0.000
C25.2 Tail of pancreas	0.096	0.904	0.000
M54.5 Low back pain	0.000	0.904	0.096
M54 Dorsalgia	0.000	0.905	0.095
M54.57 Low back pain (Lumbosacral region)	0.000	0.907	0.093
M30 Polyarteritis nodosa and related conditions	0.000	0.908	0.092
M33 Dermatopolymyositis	0.000	0.910	0.090
M54.9 Dorsalgia, unspecified	0.000	0.910	0.090
C25.0 Head of pancreas	0.090	0.910	0.000
M25 Other joint disorders, not elsewhere classified	0.000	0.910	0.090
M50-M54 Other dorsopathies	0.000	0.911	0.089
C25.1 Body of pancreas	0.088	0.911	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.913	0.087
M21.2 Flexion deformity	0.000	0.913	0.087
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.914	0.086
M21.6 Other acquired deformities of ankle and foot	0.000	0.915	0.085
M32 Systemic lupus erythematosus	0.000	0.916	0.084
M54.3 Sciatica	0.000	0.916	0.084
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.917	0.083
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.920	0.080
C25.9 Pancreas, unspecified	0.078	0.921	0.000
M50 Cervical disk disorders	0.000	0.921	0.078
M21.0 Valgus deformity, not elsewhere classified	0.000	0.922	0.078
M24 Other specific joint derangements	0.000	0.922	0.077
M54.59 Low back pain (Site unspecified)	0.000	0.923	0.077
M21.7 Unequal limb length (acquired)	0.000	0.923	0.077
M25.3 Other instability of joint	0.000	0.923	0.077
M30.0 Polyarteritis nodosa	0.000	0.924	0.076
M21.3 Wrist or foot drop (acquired)	0.000	0.924	0.076
M65-M68 Disorders of synovium and tendon	0.000	0.925	0.075
M54.54 Low back pain-Thoracic	0.000	0.925	0.075
M54.36 Sciatica (Lumbar region)	0.000	0.925	0.075
M21.9 Acquired deformity of limb, unspecified	0.000	0.926	0.074
M21.8 Other specified acquired deformities of limbs	0.000	0.926	0.074
M35 Other systemic involvement of connective tissue	0.000	0.926	0.074
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.927	0.073
M21.4 Flat foot [pes planus] (acquired)	0.000	0.927	0.073
M34 Systemic sclerosis	0.000	0.927	0.073
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.927	0.073
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.927	0.073
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.927	0.073
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.927	0.073
M54.6 Pain in thoracic spine	0.000	0.929	0.070
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.930	0.070
M50.0 Cervical disk disorder with myelopathy	0.000	0.931	0.069
M25.8 Other specified joint disorders	0.000	0.931	0.069
M24.5 Contracture of joint	0.000	0.931	0.069
M54.50 Low back pain (Multiple sites in spine)	0.000	0.931	0.069
M54.53 Low back pain-Cervicothoracic	0.000	0.931	0.069
M54.51 Low back pain-Occipit-atl-axl	0.000	0.931	0.069
M21.26 Flexion deformity (Lower leg)	0.000	0.931	0.069
M21.24 Flexion deformity (Hand)	0.000	0.932	0.068
M54.0 Panniculitis affecting regions of neck and back	0.000	0.932	0.068
M67 Other disorders of synovium and tendon	0.000	0.932	0.068
M91-M94 Chondropathies	0.000	0.933	0.067
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.933	0.067
M25.0 Haemarthrosis	0.000	0.933	0.067
M33.2 Polymyositis	0.000	0.933	0.067
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.933	0.067
M54.52 Low back pain-Cervical	0.000	0.933	0.067
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.933	0.066
M30.2 Juvenile polyarteritis	0.000	0.933	0.066
M33.9 Dermatopolymyositis, unspecified	0.000	0.934	0.066
M33.1 Other dermatomyositis	0.000	0.934	0.066
M40-M43 Deforming dorsopathies	0.000	0.934	0.066
M21.23 Flexion deformity (Forearm)	0.000	0.934	0.065
M50.3 Other cervical disk degeneration	0.000	0.935	0.065
M25.4 Effusion of joint	0.000	0.935	0.065
M54.8 Other dorsalgia	0.000	0.935	0.065
M33.0 Juvenile dermatomyositis	0.000	0.935	0.065
M80-M85 Disorders of bone density and structure	0.000	0.935	0.065
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.935	0.065
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.935	0.065
M54.39 Sciatica (Site unspecified)	0.000	0.935	0.065
M25.2 Flail joint	0.000	0.935	0.065
M25.1 Fistula of joint	0.000	0.935	0.065
M54.56 Low back pain (Lumbar region)	0.000	0.936	0.064
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.936	0.064
M24.6 Ankylosis of joint	0.000	0.936	0.064
M00-M03 Infectious arthropathies	0.000	0.936	0.064
M25.31 Other instability of joint (Shoulder region)	0.000	0.936	0.064
M67.8 Other specified disorders of synovium and tendon	0.000	0.936	0.064
M54.55 Low back pain (Thoracolumbar region)	0.000	0.936	0.063
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.936	0.063
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.937	0.063
M21.20 Flexion deformity (Multiple sites)	0.000	0.937	0.063
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.937	0.063
M24.56 Contracture of joint (Lower leg)	0.000	0.937	0.063
M21.22 Flexion deformity (Upper arm)	0.000	0.937	0.063
M54.1 Radiculopathy	0.000	0.937	0.063
M50.1 Cervical disk disorder with radiculopathy	0.000	0.937	0.063
M25.37 Other instability of joint (Ankle and foot)	0.000	0.937	0.062
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.937	0.062
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.937	0.062
M21.29 Flexion deformity (Site unspecified)	0.000	0.938	0.062
M21.28 Flexion deformity (Other)	0.000	0.938	0.062
M21.21 Flexion deformity (Shoulder region)	0.000	0.938	0.062
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.939	0.061
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.939	0.061
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.939	0.061
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.939	0.061
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.939	0.061
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.939	0.061
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.939	0.061
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.939	0.061
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.939	0.061
M60-M63 Disorders of muscles	0.000	0.939	0.061
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.000	0.939	0.061
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.939	0.060
M25.9 Joint disorder, unspecified	0.000	0.940	0.060
M86-M90 Other osteopathies	0.000	0.940	0.060
M54.37 Sciatica (Lumbosacral region)	0.000	0.940	0.060
M54.35 Sciatica (Thoracolumbar region)	0.000	0.940	0.060
M54.34 Sciatica-Thoracic	0.000	0.940	0.060
M54.33 Sciatica-Cervicothoracic	0.000	0.940	0.060
M54.32 Sciatica-Cervical	0.000	0.940	0.060
M54.31 Sciatica-Occipit-atl-axl	0.000	0.940	0.060
M54.30 Sciatica (Multiple sites in spine)	0.000	0.940	0.060
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.940	0.060
M36.3 Arthropathy in other blood disorders	0.000	0.940	0.060
M36.2 Haemophilic arthropathy	0.000	0.940	0.060
M36.1 Arthropathy in neoplastic disease	0.000	0.940	0.060
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.940	0.060
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.940	0.060
M21.27 Flexion deformity (Ankle and foot)	0.000	0.940	0.060
M22 Disorders of patella	0.000	0.940	0.060
M21.1 Varus deformity, not elsewhere classified	0.000	0.940	0.059
M50.8 Other cervical disk disorders	0.000	0.941	0.059
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.941	0.059
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.941	0.059
M35.7 Hypermobility syndrome	0.000	0.941	0.059
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.941	0.059
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.941	0.059
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.942	0.058
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.942	0.058
M25.46 Effusion of joint (Lower leg)	0.000	0.942	0.058
M32.8 Other forms of systemic lupus erythematosus	0.000	0.942	0.057
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.943	0.057
M24.9 Joint derangement, unspecified	0.000	0.943	0.057
M35.8 Other specified systemic involvement of connective tissue	0.000	0.943	0.057
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.943	0.057
M25.34 Other instability of joint (Hand)	0.000	0.943	0.057
M93 Other osteochondropathies	0.000	0.944	0.056
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.944	0.056
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.944	0.056
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.944	0.056
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.944	0.056
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.944	0.056
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.944	0.056
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.944	0.056
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.944	0.056
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.944	0.056
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.944	0.055
M25.88 Other specified joint disorders (Other)	0.000	0.944	0.055
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.945	0.055
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.945	0.055
M84 Disorders of continuity of bone	0.000	0.945	0.055
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.945	0.055
M21.78 Unequal limb length (acquired)-Other	0.000	0.945	0.055
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.945	0.055
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.945	0.055
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.945	0.055
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.945	0.055
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.945	0.055
M31 Other necrotising vasculopathies	0.000	0.945	0.055
M40 Kyphosis and lordosis	0.000	0.945	0.055
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.945	0.055
M25.39 Other instability of joint (Site unspecified)	0.000	0.945	0.055
M25.38 Other instability of joint (Other)	0.000	0.945	0.055
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.945	0.055
M25.32 Other instability of joint (Upper arm)	0.000	0.945	0.055
M25.30 Other instability of joint (Multiple sites)	0.000	0.945	0.055
M53 Other dorsopathies, not elsewhere classified	0.000	0.945	0.055
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.945	0.055
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.945	0.055
M24.7 Protrusio acetabuli	0.000	0.945	0.054
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.945	0.054
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.945	0.054
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.945	0.054
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.945	0.054
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.945	0.054
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.945	0.054
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.945	0.054
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.945	0.054
M24.54 Contracture of joint (Hand)	0.000	0.946	0.054
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.946	0.054
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.946	0.054
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.000	0.946	0.054
M25.36 Other instability of joint (Lower leg)	0.000	0.946	0.054
M24.64 Ankylosis of joint (Hand)	0.000	0.946	0.054
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.946	0.054
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.946	0.053
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.946	0.053
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.946	0.053
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.946	0.053
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.946	0.053
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.946	0.053
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.946	0.053
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.946	0.053
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.947	0.053
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.947	0.053
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.947	0.053
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.947	0.053
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.947	0.053
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.947	0.053
M25.86 Other specified joint disorders (Lower leg)	0.000	0.947	0.053
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.000	0.947	0.053
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.947	0.053
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.947	0.053
M35.5 Multifocal fibrosclerosis	0.000	0.947	0.053
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.947	0.053
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.947	0.053
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.947	0.053
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.947	0.053
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.947	0.053
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.947	0.053
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.947	0.053
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.947	0.053
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.947	0.053
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.947	0.053
M65 Synovitis and tenosynovitis	0.000	0.947	0.053
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.947	0.053
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.947	0.053
M34.0 Progressive systemic sclerosis	0.000	0.947	0.052
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.947	0.052
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.947	0.052
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.947	0.052
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.947	0.052
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.947	0.052
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.947	0.052
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.947	0.052
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.947	0.052
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.947	0.052
M34.8 Other forms of systemic sclerosis	0.000	0.947	0.052
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.948	0.052
M25.83 Other specified joint disorders (Forearm)	0.000	0.948	0.052
M66 Spontaneous rupture of synovium and tendon	0.000	0.948	0.052
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.948	0.052
M25.33 Other instability of joint (Forearm)	0.000	0.948	0.052
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.948	0.052
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.948	0.052
M35.2 Behcet's disease	0.000	0.948	0.051
M54.2 Cervicalgia	0.000	0.948	0.051
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.000	0.949	0.051
M45-M49 Spondylopathies	0.000	0.949	0.051
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.949	0.051
M25.06 Haemarthrosis (Lower leg)	0.000	0.949	0.051
M35.1 Other overlap syndromes	0.000	0.949	0.051
M54.12 Radiculopathy (Cervical region)	0.000	0.949	0.051
M54.69 Pain in thoracic spine-Site unspe	0.000	0.949	0.051
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.000	0.949	0.051
M54.67 Pain in thoracic spine-Lumbosacral	0.000	0.949	0.051
M54.66 Pain in thoracic spine-Lumbar	0.000	0.949	0.051
M54.62 Pain in thoracic spine-Cervical	0.000	0.949	0.051
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.000	0.949	0.051
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.000	0.949	0.051
M80 Osteoporosis with pathological fracture	0.000	0.949	0.051
M35.0 Sicca syndrome [Sjogren]	0.000	0.949	0.051
M67.4 Ganglion	0.000	0.949	0.050
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.950	0.050
M24.2 Disorder of ligament	0.000	0.950	0.050
M24.0 Loose body in joint	0.000	0.950	0.050
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.950	0.050
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.950	0.050
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.950	0.050
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.950	0.050
M92 Other juvenile osteochondrosis	0.000	0.950	0.050
M24.59 Contracture of joint (Site unspecified)	0.000	0.950	0.050
M24.58 Contracture of joint (Other)	0.000	0.950	0.050
M24.53 Contracture of joint (Forearm)	0.000	0.950	0.050
M24.50 Contracture of joint (Multiple sites)	0.000	0.950	0.050
M60 Myositis	0.000	0.950	0.050
M67.0 Short Achilles tendon (acquired)	0.000	0.950	0.049
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.950	0.049
M24.52 Contracture of joint (Upper arm)	0.000	0.951	0.049
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.951	0.049
M34.1 CR(E)ST syndrome	0.000	0.951	0.049
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.000	0.951	0.049
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.000	0.951	0.049
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.000	0.951	0.049
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.000	0.951	0.049
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.000	0.951	0.049
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.000	0.951	0.049
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.000	0.951	0.049
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.000	0.951	0.049
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.000	0.951	0.049
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.000	0.951	0.049
M24.57 Contracture of joint (Ankle and foot)	0.000	0.951	0.049
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.951	0.049
M67.3 Transient synovitis	0.000	0.951	0.049
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.951	0.049
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.951	0.049
M42 Spinal osteochondrosis	0.000	0.951	0.049
M54.4 Lumbago with sciatica	0.000	0.951	0.048
M25.09 Haemarthrosis (Site unspecified)	0.000	0.952	0.048
M25.08 Haemarthrosis (Other)	0.000	0.952	0.048
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.952	0.048
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.952	0.048
M25.04 Haemarthrosis (Hand)	0.000	0.952	0.048
M25.03 Haemarthrosis (Forearm)	0.000	0.952	0.048
M25.02 Haemarthrosis (Upper arm)	0.000	0.952	0.048
M25.01 Haemarthrosis (Shoulder region)	0.000	0.952	0.048
M25.00 Haemarthrosis (Multiple sites)	0.000	0.952	0.048
M54.84 Other dorsalgia (Thoracic region)	0.000	0.952	0.048
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.952	0.048
M67.1 Other contracture of tendon (sheath)	0.000	0.952	0.048
M25.7 Osteophyte	0.000	0.952	0.048
M25.82 Other specified joint disorders (Upper arm)	0.000	0.952	0.048
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.952	0.047
M50.9 Cervical disk disorder, unspecified	0.000	0.952	0.047
M05-M14 Inflammatory polyarthropathies	0.000	0.952	0.048
M00 Pyogenic arthritis	0.000	0.953	0.047
M24.66 Ankylosis of joint (Lower leg)	0.000	0.953	0.047
M54.87 Other dorsalgia (Lumbosacral region)	0.000	0.953	0.047
M91 Juvenile osteochondrosis of hip and pelvis	0.000	0.953	0.047
M40.2 Other and unspecified kyphosis	0.000	0.953	0.047
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.000	0.953	0.047
M25.49 Effusion of joint (Site unspecified)	0.000	0.953	0.047
M25.48 Effusion of joint (Other)	0.000	0.953	0.047
M81 Osteoporosis without pathological fracture	0.000	0.953	0.047
M54.85 Other dorsalgia (Thoracolumbar region)	0.000	0.953	0.047
M54.83 Other dorsalgia (Cervicothoracic region)	0.000	0.953	0.047
M54.82 Other dorsalgia (Cervical region)	0.000	0.953	0.047
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.000	0.953	0.047
M25.42 Effusion of joint (Upper arm)	0.000	0.953	0.047
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.953	0.047
M43 Other deforming dorsopathies	0.000	0.953	0.047
M25.84 Other specified joint disorders (Hand)	0.000	0.953	0.047
M83 Adult osteomalacia	0.000	0.953	0.047
M25.19 Fistula of joint (Site unspecified)	0.000	0.953	0.046
M25.18 Fistula of joint (Other)	0.000	0.953	0.046
M25.17 Fistula of joint (Ankle and foot)	0.000	0.953	0.046
M25.16 Fistula of joint (Lower leg)	0.000	0.953	0.046
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.953	0.046
M25.14 Fistula of joint (Hand)	0.000	0.953	0.046
M25.13 Fistula of joint (Forearm)	0.000	0.953	0.046
M25.12 Fistula of joint (Upper arm)	0.000	0.953	0.046
M25.11 Fistula of joint (Shoulder region)	0.000	0.953	0.046
M25.10 Fistula of joint (Multiple sites)	0.000	0.953	0.046
M25.29 Flail joint (Site unspecified)	0.000	0.953	0.046
M25.28 Flail joint (Other)	0.000	0.953	0.046
M25.27 Flail joint (Ankle and foot)	0.000	0.953	0.046
M25.26 Flail joint (Lower leg)	0.000	0.953	0.046
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.953	0.046
M25.24 Flail joint (Hand)	0.000	0.953	0.046
M25.23 Flail joint (Forearm)	0.000	0.953	0.046
M25.22 Flail joint (Upper arm)	0.000	0.953	0.046
M25.21 Flail joint (Shoulder region)	0.000	0.953	0.046
M25.20 Flail joint (Multiple sites)	0.000	0.953	0.046
M24.51 Contracture of joint (Shoulder region)	0.000	0.954	0.046
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.954	0.046
M84.4 Pathological fracture, not elsewhere classified	0.000	0.954	0.046
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.954	0.046
M24.68 Ankylosis of joint (Other)	0.000	0.954	0.046
M24.63 Ankylosis of joint (Forearm)	0.000	0.954	0.046
M24.62 Ankylosis of joint (Upper arm)	0.000	0.954	0.046
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.954	0.046
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.954	0.046
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.954	0.046
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.954	0.046
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.954	0.046
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.954	0.046
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.000	0.954	0.046
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.000	0.954	0.046
M54.14 Radiculopathy (Thoracic region)	0.000	0.954	0.046
M89 Other disorders of bone	0.000	0.954	0.046
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.954	0.045
M25.94 Joint disorder, unspecified (Hand)	0.000	0.954	0.045
M54.89 Other dorsalgia (Site unspecified)	0.000	0.955	0.045
M02 Reactive arthropathies	0.000	0.955	0.045
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.955	0.045
M54.86 Other dorsalgia (Lumbar region)	0.000	0.955	0.045
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.955	0.045
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.955	0.045
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.955	0.045
M22.0 Recurrent dislocation of patella	0.000	0.955	0.045
M93.9 Osteochondropathy, unspecified	0.000	0.955	0.045
M54.80 Other dorsalgia (Multiple sites in spine)	0.000	0.955	0.045
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.955	0.045
M93.1 Kienbock's disease of adults	0.000	0.955	0.045
M25.43 Effusion of joint (Forearm)	0.000	0.955	0.045
M34.9 Systemic sclerosis, unspecified	0.000	0.955	0.045
M25.5 Pain in joint	0.000	0.955	0.045
M54.19 Radiculopathy (Site unspecified)	0.000	0.955	0.045
M99 Biomechanical lesions, not elsewhere classified	0.000	0.955	0.045
M22.9 Disorder of patella, unspecified	0.000	0.955	0.044
M50.2 Other cervical disk displacement	0.000	0.955	0.044
M86 Osteomyelitis	0.000	0.955	0.044
M87 Osteonecrosis	0.000	0.956	0.044
M25.98 Joint disorder, unspecified (Other)	0.000	0.956	0.044
M25.47 Effusion of joint (Ankle and foot)	0.000	0.956	0.044
M63 Disorders of muscle in diseases classified elsewhere	0.000	0.956	0.044
M61 Calcification and ossification of muscle	0.000	0.956	0.044
M25.44 Effusion of joint (Hand)	0.000	0.956	0.044
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.956	0.043
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.956	0.043
M25.41 Effusion of joint (Shoulder region)	0.000	0.956	0.043
M94 Other disorders of cartilage	0.000	0.957	0.043
M22.1 Recurrent subluxation of patella	0.000	0.957	0.043
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.957	0.043
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.957	0.043
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.957	0.043
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.957	0.043
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.957	0.043
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.957	0.043
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.957	0.043
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.957	0.043
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.957	0.043
M25.40 Effusion of joint (Multiple sites)	0.000	0.957	0.043
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.957	0.043
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.958	0.042
M90 Osteopathies in diseases classified elsewhere	0.000	0.958	0.042
M07 Psoriatic and enteropathic arthropathies	0.000	0.958	0.042
M22.3 Other derangements of patella	0.000	0.958	0.042
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.958	0.042
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.958	0.042
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.958	0.042
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.958	0.042
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.958	0.042
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.958	0.042
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.958	0.042
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.958	0.042

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations