TreeWAS – Variant ID: rs7651446

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I84.1 Internal haemorrhoids with other complications	0.000	0.739	0.261
I35.0 Aortic (valve) stenosis	0.028	0.972	0.000
I35 Nonrheumatic aortic valve disorders	0.026	0.974	0.000
I35.1 Aortic (valve) insufficiency	0.025	0.975	0.000
I35.8 Other aortic valve disorders	0.023	0.977	0.000
K30 Dyspepsia	0.000	0.980	0.020
I35.2 Aortic (valve) stenosis with insufficiency	0.020	0.980	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.019	0.981	0.000
I77.1 Stricture of artery	0.018	0.981	0.000
I71 Aortic aneurysm and dissection	0.018	0.982	0.000
I77 Other disorders of arteries and arterioles	0.018	0.982	0.000
I35.9 Aortic valve disorder, unspecified	0.017	0.983	0.000
I78 Diseases of capillaries	0.017	0.983	0.000
I74 Arterial embolism and thrombosis	0.017	0.983	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.017	0.983	0.000
I78.1 Naevus, nonneoplastic	0.016	0.984	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.016	0.984	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.015	0.985	0.000
I71.0 Dissection of aorta [any part]	0.015	0.985	0.000
I70 Atherosclerosis	0.015	0.985	0.000
I74.5 Embolism and thrombosis of iliac artery	0.014	0.986	0.000
I73 Other peripheral vascular diseases	0.014	0.986	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.013	0.987	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.013	0.987	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.013	0.987	0.000
I72 Other aneurysm	0.013	0.987	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.013	0.987	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.013	0.987	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.013	0.987	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.013	0.987	0.000
I77.5 Necrosis of artery	0.013	0.987	0.000
I77.4 Coeliac artery compression syndrome	0.013	0.987	0.000
I77.3 Arterial fibromuscular dysplasia	0.013	0.987	0.000
I77.2 Rupture of artery	0.013	0.987	0.000
I77.0 Arteriovenous fistula, acquired	0.013	0.987	0.000
I74.8 Embolism and thrombosis of other arteries	0.013	0.987	0.000
I78.9 Disease of capillaries, unspecified	0.012	0.988	0.000
I78.8 Other diseases of capillaries	0.012	0.988	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.012	0.988	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.012	0.988	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.012	0.988	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.012	0.988	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.012	0.988	0.000
I73.9 Peripheral vascular disease, unspecified	0.012	0.988	0.000
I77.6 Arteritis, unspecified	0.012	0.988	0.000
I70.0 Atherosclerosis of aorta	0.012	0.988	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.012	0.988	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.011	0.988	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.011	0.989	0.000
I70.9 Generalised and unspecified atherosclerosis	0.011	0.989	0.000
I70.8 Atherosclerosis of other arteries	0.011	0.989	0.000
I70.1 Atherosclerosis of renal artery	0.011	0.989	0.000
I77.8 Other specified disorders of arteries and arterioles	0.011	0.989	0.000
I72.2 Aneurysm of renal artery	0.011	0.989	0.000
I73.8 Other specified peripheral vascular diseases	0.010	0.990	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.010	0.990	0.000
I72.8 Aneurysm of other specified arteries	0.010	0.990	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.010	0.990	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.010	0.990	0.000
I79.1 Aortitis in diseases classified elsewhere	0.010	0.990	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.010	0.990	0.000
I72.9 Aneurysm of unspecified site	0.009	0.990	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.009	0.990	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.009	0.990	0.000
I72.1 Aneurysm of artery of upper extremity	0.009	0.990	0.000
I72.0 Aneurysm of carotid artery	0.009	0.990	0.000
I42 Cardiomyopathy	0.009	0.991	0.000
I72.3 Aneurysm of iliac artery	0.009	0.991	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.009	0.991	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.009	0.991	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.009	0.991	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.009	0.991	0.000
I42.9 Cardiomyopathy, unspecified	0.009	0.991	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.009	0.991	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.008	0.991	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.008	0.992	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.008	0.992	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.008	0.992	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.008	0.992	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.008	0.992	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.008	0.992	0.000
H02.9 Disorder of eyelid, unspecified	0.008	0.992	0.000
I42.2 Other hypertrophic cardiomyopathy	0.008	0.992	0.000
I84 Haemorrhoids	0.000	0.992	0.008
I72.4 Aneurysm of artery of lower extremity	0.008	0.992	0.000
I34 Nonrheumatic mitral valve disorders	0.008	0.992	0.000
I30-I52 Other forms of heart disease	0.008	0.992	0.000
I42.8 Other cardiomyopathies	0.007	0.993	0.000
I45 Other conduction disorders	0.007	0.993	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.000	0.993	0.007
H02.4 Ptosis of eyelid	0.007	0.993	0.000
I33 Acute and subacute endocarditis	0.007	0.993	0.000
I42.6 Alcoholic cardiomyopathy	0.007	0.993	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.007	0.993	0.000
I42.5 Other restrictive cardiomyopathy	0.007	0.993	0.000
I42.4 Endocardial fibroelastosis	0.007	0.993	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.007	0.993	0.000
I34.0 Mitral (valve) insufficiency	0.007	0.993	0.000
I73.0 Raynaud's syndrome	0.007	0.993	0.000
I33.0 Acute and subacute infective endocarditis	0.007	0.993	0.000
H02 Other disorders of eyelid	0.007	0.993	0.000
I34.1 Mitral (valve) prolapse	0.007	0.993	0.000
I42.0 Dilated cardiomyopathy	0.007	0.993	0.000
I45.3 Trifascicular block	0.007	0.993	0.000
I45.1 Other and unspecified right bundle-branch block	0.007	0.993	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.007	0.993	0.000
I84.8 Unspecified haemorrhoids with other complications	0.000	0.993	0.007
I84.3 External thrombosed haemorrhoids	0.000	0.994	0.006
K56.6 Other and unspecified intestinal obstruction	0.006	0.994	0.000
I84.0 Internal thrombosed haemorrhoids	0.000	0.994	0.006
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.006	0.994	0.000
I45.6 Preexcitation syndrome	0.006	0.994	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.006	0.994	0.000
I52 Other heart disorders in diseases classified elsewhere	0.006	0.994	0.000
I48 Atrial fibrillation and flutter	0.006	0.994	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.006	0.994	0.000
I41 Myocarditis in diseases classified elsewhere	0.006	0.994	0.000
I40 Acute myocarditis	0.006	0.994	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I32 Pericarditis in diseases classified elsewhere	0.006	0.994	0.000
H02.1 Ectropion of eyelid	0.006	0.994	0.000
I37 Pulmonary valve disorders	0.006	0.994	0.000
I36 Nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.994	0.006
H02.8 Other specified disorders of eyelid	0.006	0.994	0.000
I45.8 Other specified conduction disorders	0.005	0.994	0.000
I45.4 Nonspecific intraventricular block	0.005	0.994	0.000
I45.2 Bifascicular block	0.005	0.994	0.000
I45.0 Right fascicular block	0.005	0.994	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.005	0.995	0.000
I33.9 Acute endocarditis, unspecified	0.005	0.995	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.005	0.995	0.000
H02.2 Lagophthalmos	0.005	0.995	0.000
I30 Acute pericarditis	0.005	0.995	0.000
E66.8 Other obesity	0.005	0.995	0.000
I84.4 External haemorrhoids with other complications	0.000	0.995	0.005
H02.3 Blepharochalasis	0.005	0.995	0.000
H74.4 Polyp of middle ear	0.005	0.995	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.005	0.995	0.000
H02.6 Xanthelasma of eyelid	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.005	0.995	0.000
I31 Other diseases of pericardium	0.005	0.995	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.995	0.005
N32.9 Bladder disorder, unspecified	0.005	0.995	0.000
I45.9 Conduction disorder, unspecified	0.004	0.995	0.000
I45.5 Other specified heart block	0.004	0.995	0.000
H04 Disorders of lachrymal system	0.005	0.995	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.004	0.995	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.004	0.995	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.004	0.995	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.004	0.995	0.000
I40.9 Acute myocarditis, unspecified	0.004	0.995	0.000
I40.8 Other acute myocarditis	0.004	0.995	0.000
I40.1 Isolated myocarditis	0.004	0.995	0.000
I40.0 Infective myocarditis	0.004	0.995	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.004	0.995	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.004	0.995	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.004	0.995	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.004	0.995	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.004	0.995	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.004	0.995	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.004	0.995	0.000
I48.4 Atypical atrial flutter	0.004	0.995	0.000
I48.3 Typical atrial flutter	0.004	0.995	0.000
I48.2 Chronic atrial fibrillation	0.004	0.995	0.000
I48.1 Persistent atrial fibrillation	0.004	0.995	0.000
I48.0 Paroxysmal atrial fibrillation	0.004	0.995	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.004	0.995	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.004	0.995	0.000
H05 Disorders of orbit	0.004	0.996	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.004	0.996	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.004	0.996	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.004	0.996	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.004	0.996	0.000
I37.9 Pulmonary valve disorder, unspecified	0.004	0.996	0.000
I37.8 Other pulmonary valve disorders	0.004	0.996	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.004	0.996	0.000
I37.0 Pulmonary valve stenosis	0.004	0.996	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.004	0.996	0.000
I46 Cardiac arrest	0.004	0.996	0.000
H65-H75 Diseases of middle ear and mastoid	0.004	0.996	0.000
H04.2 Epiphora	0.004	0.996	0.000
H05.9 Disorder of orbit, unspecified	0.004	0.996	0.000
H02.5 Other disorders affecting eyelid function	0.004	0.996	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.004	0.996	0.000
I37.1 Pulmonary valve insufficiency	0.004	0.996	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.004	0.996	0.000
H04.8 Other disorders of lachrymal system	0.004	0.996	0.000
I38 Endocarditis, valve unspecified	0.004	0.996	0.000
I30.8 Other forms of acute pericarditis	0.004	0.996	0.000
I30.1 Infective pericarditis	0.004	0.996	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.004	0.996	0.000
H93.1 Tinnitus	0.004	0.996	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.004	0.996	0.000
H01 Other inflammation of eyelid	0.004	0.996	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
I50 Heart failure	0.004	0.996	0.000
E66 Obesity	0.004	0.996	0.000
I50.1 Left ventricular failure	0.004	0.996	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.004	0.996	0.000
H74.1 Adhesive middle ear disease	0.004	0.996	0.000
H04.4 Chronic inflammation of lachrymal passages	0.004	0.996	0.000
I31.8 Other specified diseases of pericardium	0.003	0.996	0.000
I31.2 Haemopericardium, not elsewhere classified	0.003	0.996	0.000
I31.1 Chronic constrictive pericarditis	0.003	0.996	0.000
I31.0 Chronic adhesive pericarditis	0.003	0.996	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.996	0.004
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.996	0.000
I84.5 External haemorrhoids without complication	0.000	0.996	0.004
H70 Mastoiditis and related conditions	0.003	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.996	0.000
H05.2 Exophthalmic conditions	0.003	0.996	0.000
H04.9 Disorder of lachrymal system, unspecified	0.003	0.996	0.000
H04.6 Other changes in lachrymal passages	0.003	0.996	0.000
H04.0 Dacryoadenitis	0.003	0.996	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.996	0.003
H69 Other disorders of Eustachian tube	0.003	0.996	0.000
N32.3 Diverticulum of bladder	0.003	0.997	0.000
E66.9 Obesity, unspecified	0.003	0.997	0.000
Z51.8 Other specified medical care	0.000	0.997	0.003
H05.8 Other disorders of orbit	0.003	0.997	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.003	0.997	0.000
H05.4 Enophthalmos	0.003	0.997	0.000
H05.3 Deformity of orbit	0.003	0.997	0.000
H05.1 Chronic inflammatory disorders of orbit	0.003	0.997	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.003	0.997	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.003	0.997	0.000
I46.1 Sudden cardiac death, so described	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.997	0.003
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.003	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.003	0.997	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.997	0.003
H66.9 Otitis media, unspecified	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
N32 Other disorders of bladder	0.003	0.997	0.000
Z12 Special screening examination for neoplasms	0.000	0.997	0.003
I30.9 Acute pericarditis, unspecified	0.003	0.997	0.000
I31.9 Disease of pericardium, unspecified	0.003	0.997	0.000
H02.0 Entropion and trichiasis of eyelid	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
E66.0 Obesity due to excess calories	0.003	0.997	0.000
H01.0 Blepharitis	0.003	0.997	0.000
I47 Paroxysmal tachycardia	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
H66.0 Acute suppurative otitis media	0.003	0.997	0.000
H01.9 Inflammation of eyelid, unspecified	0.003	0.997	0.000
H01.8 Other specified inflammation of eyelid	0.003	0.997	0.000
H01.1 Non-infectious dermatoses of eyelid	0.003	0.997	0.000
H06.2 Dysthyroid exophthalmos	0.003	0.997	0.000
H00 Hordeolum and chalazion	0.003	0.997	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.003	0.997	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.003	0.997	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.003	0.997	0.000
E66.1 Drug-induced obesity	0.003	0.997	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.997	0.003
I31.3 Pericardial effusion (noninflammatory)	0.003	0.997	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.997	0.003
E16.2 Hypoglycaemia, unspecified	0.000	0.997	0.003
I46.9 Cardiac arrest, unspecified	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H61 Other disorders of external ear	0.003	0.997	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.997	0.003
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
H69.0 Patulous Eustachian tube	0.003	0.997	0.000
C44.0 Skin of lip	0.003	0.997	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.997	0.000
H68.0 Eustachian salpingitis	0.002	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.002	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
I47.0 Reentry ventricular arrhythmia	0.002	0.997	0.000
N32.8 Other specified disorders of bladder	0.003	0.997	0.000
N32.4 Rupture of bladder, nontraumatic	0.002	0.997	0.000
N32.2 Vesical fistula, not elsewhere classified	0.002	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.997	0.002
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.997	0.002
Z12.9 Special screening examination for neoplasm, unspecified	0.000	0.997	0.002
Z12.6 Special screening examination for neoplasm of bladder	0.000	0.997	0.002
Z12.4 Special screening examination for neoplasm of cervix	0.000	0.997	0.002
Z12.3 Special screening examination for neoplasm of breast	0.000	0.997	0.002
Z12.2 Special screening examination for neoplasm of respiratory organs	0.000	0.997	0.002
H60-H62 Diseases of external ear	0.003	0.997	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
H61.1 Non-infective disorders of pinna	0.002	0.997	0.000
N32.1 Vesicointestinal fistula	0.002	0.997	0.000
H50.9 Strabismus, unspecified	0.002	0.997	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.997	0.002
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.000	0.998	0.002
C44.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.998	0.000
K76 Other diseases of liver	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.002	0.998	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
Chapter IX Diseases of the circulatory system	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
H80-H83 Diseases of inner ear	0.002	0.998	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.000	0.998	0.002
H90-H95 Other disorders of ear	0.002	0.998	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
H83 Other diseases of inner ear	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
C44.4 Skin of scalp and neck	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
I49 Other cardiac arrhythmias	0.002	0.998	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
H83.0 Labyrinthitis	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
C44 Other malignant neoplasms of skin	0.002	0.998	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.998	0.002
K76.7 Hepatorenal syndrome	0.002	0.998	0.000
K76.5 Hepatic veno-occlusive disease	0.002	0.998	0.000
K76.4 Peliosis hepatis	0.002	0.998	0.000
K76.3 Infarction of liver	0.002	0.998	0.000
K76.2 Central haemorrhagic necrosis of liver	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.998	0.000
G35 Multiple sclerosis	0.002	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.002	0.998	0.000
I00-I02 Acute rheumatic fever	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
Z03.8 Observation for other suspected diseases and conditions	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
K56.0 Paralytic ileus	0.002	0.998	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.998	0.002
H50 Other strabismus	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
I25.2 Old myocardial infarction	0.002	0.998	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
G57.8 Other mononeuropathies of lower limb	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
K56.3 Gallstone ileus	0.002	0.998	0.000
N32.0 Bladder-neck obstruction	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
C44.8 Overlapping lesion of skin	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
C18.0 Caecum	0.000	0.998	0.002
C44.9 Malignant neoplasm of skin, unspecified	0.002	0.998	0.000
I47.2 Ventricular tachycardia	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.002	0.998	0.000
I44.4 Left anterior fascicular block	0.002	0.998	0.000
I49.9 Cardiac arrhythmia, unspecified	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.000	0.998	0.002
H60 Otitis externa	0.001	0.998	0.000
H80 Otosclerosis	0.001	0.998	0.000
I02 Rheumatic chorea	0.001	0.998	0.000
I01 Rheumatic fever with heart involvement	0.001	0.998	0.000
I00 Rheumatic fever without mention of heart involvement	0.001	0.998	0.000
K76.8 Other specified diseases of liver	0.002	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
G54.8 Other nerve root and plexus disorders	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
G54 Nerve root and plexus disorders	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
H81.8 Other disorders of vestibular function	0.001	0.998	0.000
H81.4 Vertigo of central origin	0.001	0.998	0.000
H81.3 Other peripheral vertigo	0.001	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.001	0.998	0.000
I06 Rheumatic aortic valve diseases	0.001	0.998	0.000
C44.5 Skin of trunk	0.002	0.998	0.000
G54.6 Phantom limb syndrome with pain	0.002	0.998	0.000
H50.8 Other specified strabismus	0.001	0.998	0.000
H50.6 Mechanical strabismus	0.001	0.998	0.000
H50.5 Heterophoria	0.001	0.998	0.000
H50.4 Other and unspecified heterotropia	0.001	0.998	0.000
H50.3 Intermittent heterotropia	0.001	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.001	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.001	0.998	0.000
K76.9 Liver disease, unspecified	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.001	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.998	0.002
L60.8 Other nail disorders	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.001	0.998	0.000
H50.2 Vertical strabismus	0.001	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.001	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.001	0.998	0.000
I49.3 Ventricular premature depolarisation	0.001	0.998	0.000
I50.9 Heart failure, unspecified	0.001	0.998	0.000
K56.1 Intussusception	0.001	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.001
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.001
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.001
E16.3 Increased secretion of glucagon	0.000	0.998	0.001
E16.1 Other hypoglycaemia	0.000	0.998	0.001
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.001
G54.4 Lumbosacral root disorders, not elsewhere classified	0.001	0.998	0.000
I49.1 Atrial premature depolarisation	0.001	0.998	0.000
S32.1 Fracture of sacrum	0.001	0.998	0.000
I05 Rheumatic mitral valve diseases	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations