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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76531899
log Bayes Factor = 13.8951
Chromosome 5   position 109,156,748  (GRCh37) Explore rs76531899 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
M15-M19 Arthrosis
0.994 0.006 0.000
M17 Gonarthrosis [arthrosis of knee]
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.989 0.011 0.000
M17.1 Other primary gonarthrosis
0.985 0.015 0.000
M17.9 Gonarthrosis, unspecified
0.984 0.016 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.981 0.019 0.000
M20-M25 Other joint disorders
0.975 0.025 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.967 0.033 0.000
E70-E90 Metabolic disorders
0.964 0.036 0.000
I25.1 Atherosclerotic heart disease
0.963 0.037 0.000
M23 Internal derangement of knee
0.961 0.039 0.000
I10-I15 Hypertensive diseases
0.958 0.042 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.958 0.042 0.000
M70-M79 Other soft tissue disorders
0.958 0.042 0.000
M23.3 Other meniscus derangements
0.949 0.051 0.000
Chapter XIV Diseases of the genitourinary system
0.948 0.052 0.000
Chapter VI Diseases of the nervous system
0.941 0.059 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.941 0.059 0.000
Chapter X Diseases of the respiratory system
0.936 0.064 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.934 0.066 0.000
I26 Pulmonary embolism
0.933 0.067 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.933 0.067 0.000
M65-M68 Disorders of synovium and tendon
0.931 0.069 0.000
Chapter V Mental and behavioural disorders
0.931 0.069 0.000
I10 Essential (primary) hypertension
0.930 0.070 0.000
L20-L30 Dermatitis and eczema
0.926 0.074 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.921 0.079 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.906 0.094 0.000
I27 Other pulmonary heart diseases
0.903 0.097 0.000
J90-J94 Other diseases of pleura
0.898 0.102 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.898 0.102 0.000
N40-N51 Diseases of male genital organs
0.896 0.104 0.000
I20 Angina pectoris
0.892 0.108 0.000
E65-E68 Obesity and other hyperalimentation
0.888 0.112 0.000
O20 Haemorrhage in early pregnancy
0.886 0.114 0.000
Chapter XX External causes of morbidity and mortality
0.876 0.124 0.000
L27 Dermatitis due to substances taken internally
0.875 0.125 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.875 0.125 0.000
E87.5 Hyperkalaemia
0.871 0.129 0.000
G90-G99 Other disorders of the nervous system
0.869 0.131 0.000
Chapter XI Diseases of the digestive system
0.867 0.133 0.000
I60-I69 Cerebrovascular diseases
0.865 0.135 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.862 0.138 0.000
O16 Unspecified maternal hypertension
0.858 0.142 0.000
I20.0 Unstable angina
0.858 0.142 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.857 0.143 0.000
F30-F39 Mood [affective] disorders
0.855 0.145 0.000
J20-J22 Other acute lower respiratory infections
0.854 0.146 0.000
N10-N16 Renal tubulo-interstitial diseases
0.853 0.147 0.000
J09-J18 Influenza and pneumonia
0.850 0.150 0.000
M79.8 Other specified soft tissue disorders
0.847 0.153 0.000
L50-L54 Urticaria and erythema
0.845 0.155 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.843 0.157 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.840 0.160 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.840 0.160 0.000
M31 Other necrotising vasculopathies
0.839 0.161 0.000
J90 Pleural effusion, not elsewhere classified
0.839 0.161 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.839 0.161 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.838 0.162 0.000
M67 Other disorders of synovium and tendon
0.833 0.167 0.000
O47 False labour
0.832 0.168 0.000
M40-M43 Deforming dorsopathies
0.825 0.175 0.000
M76 Enthesopathies of lower limb, excluding foot
0.823 0.177 0.000
E87.2 Acidosis
0.822 0.178 0.000
I27.0 Primary pulmonary hypertension
0.822 0.178 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.820 0.180 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.820 0.180 0.000
E66 Obesity
0.814 0.186 0.000
N42 Other disorders of prostate
0.813 0.187 0.000
I80 Phlebitis and thrombophlebitis
0.813 0.187 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.813 0.187 0.000
O42 Premature rupture of membranes
0.808 0.192 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.806 0.194 0.000
M05-M14 Inflammatory polyarthropathies
0.806 0.194 0.000
K70-K77 Diseases of liver
0.805 0.195 0.000
N20-N23 Urolithiasis
0.804 0.196 0.000
I22 Subsequent myocardial infarction
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
E10-E14 Diabetes mellitus
0.799 0.201 0.000
M65 Synovitis and tenosynovitis
0.798 0.202 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.798 0.202 0.000
O00-O08 Pregnancy with abortive outcome
0.796 0.204 0.000
N40 Hyperplasia of prostate
0.795 0.205 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.793 0.207 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.793 0.207 0.000
M79.6 Pain in limb
0.792 0.208 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.792 0.208 0.000
W00-W19 Falls
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.209 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.790 0.210 0.000
M24 Other specific joint derangements
0.790 0.210 0.000
M23.4 Loose body in knee
0.788 0.212 0.000
E88 Other metabolic disorders
0.787 0.213 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.786 0.214 0.000
L28 Lichen simplex chronicus and prurigo
0.783 0.217 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.782 0.218 0.000
L53 Other erythematous conditions
0.781 0.219 0.000
E00-E07 Disorders of thyroid gland
0.780 0.220 0.000
K90-K93 Other diseases of the digestive system
0.778 0.222 0.000
I25.2 Old myocardial infarction
0.778 0.222 0.000
O48 Prolonged pregnancy
0.778 0.222 0.000
M91-M94 Chondropathies
0.775 0.225 0.000
M23.8 Other internal derangements of knee
0.774 0.225 0.000
J22 Unspecified acute lower respiratory infection
0.774 0.226 0.000
J91 Pleural effusion in conditions classified elsewhere
0.770 0.230 0.000
O43 Placental disorders
0.769 0.231 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.769 0.231 0.000
Y40 Systemic antibiotics
0.769 0.231 0.000
N30-N39 Other diseases of urinary system
0.767 0.233 0.000
O85-O92 Complications predominantly related to the puerperium
0.766 0.234 0.000
I85 Oesophageal varices
0.766 0.234 0.000
S60-S69 Injuries to the wrist and hand
0.765 0.235 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.764 0.236 0.000
M67.8 Other specified disorders of synovium and tendon
0.763 0.237 0.000
N43 Hydrocele and spermatocele
0.763 0.237 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.763 0.237 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.762 0.238 0.000
F33 Recurrent depressive disorder
0.762 0.238 0.000
E87.7 Fluid overload
0.762 0.238 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.761 0.239 0.000
N17-N19 Renal failure
0.761 0.239 0.000
M86-M90 Other osteopathies
0.760 0.240 0.000
O80-O84 Delivery
0.760 0.240 0.000
S80-S89 Injuries to the knee and lower leg
0.758 0.242 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.758 0.242 0.000
K76 Other diseases of liver
0.758 0.242 0.000
M45-M49 Spondylopathies
0.757 0.243 0.000
L29 Pruritus
0.757 0.243 0.000
E20-E35 Disorders of other endocrine glands
0.756 0.244 0.000
M80-M85 Disorders of bone density and structure
0.755 0.244 0.000
M17.3 Other posttraumatic gonarthrosis
0.755 0.245 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.754 0.246 0.000
K08 Other disorders of teeth and supporting structures
0.752 0.248 0.000
I25.5 Ischaemic cardiomyopathy
0.752 0.248 0.000
G20-G26 Extrapyramidal and movement disorders
0.751 0.249 0.000
F32 Depressive episode
0.750 0.250 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.750 0.250 0.000
S90-S99 Injuries to the ankle and foot
0.749 0.251 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.747 0.253 0.000
M21 Other acquired deformities of limbs
0.746 0.254 0.000
E14 Unspecified diabetes mellitus
0.745 0.255 0.000
O44 Placenta praevia
0.744 0.256 0.000
G70-G73 Diseases of myoneural junction and muscle
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
M31.6 Other giant cell arteritis
0.742 0.258 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.742 0.258 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.742 0.258 0.000
O36 Maternal care for other known or suspected foetal problems
0.740 0.260 0.000
M72 Fibroblastic disorders
0.739 0.261 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.737 0.262 0.000
O20.0 Threatened abortion
0.737 0.263 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.737 0.263 0.000
S70-S79 Injuries to the hip and thigh
0.736 0.264 0.000
W19 Unspecified fall
0.736 0.264 0.000
L53.9 Erythematous condition, unspecified
0.736 0.264 0.000
E40-E46 Malnutrition
0.733 0.267 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.733 0.267 0.000
E83 Disorders of mineral metabolism
0.733 0.267 0.000
I05-I09 Chronic rheumatic heart diseases
0.731 0.269 0.000
Chapter VIII Diseases of the ear and mastoid process
0.730 0.270 0.000
M71 Other bursopathies
0.730 0.270 0.000
I69 Sequelae of cerebrovascular disease
0.728 0.272 0.000
O60-O75 Complications of labour and delivery
0.728 0.272 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.728 0.272 0.000
M76.6 Achilles tendinitis
0.727 0.273 0.000
G95 Other diseases of spinal cord
0.727 0.273 0.000
N42.9 Disorder of prostate, unspecified
0.724 0.276 0.000
G93 Other disorders of brain
0.724 0.276 0.000
L60-L75 Disorders of skin appendages
0.723 0.277 0.000
Y40.0 Penicillins
0.722 0.278 0.000
I24 Other acute ischaemic heart diseases
0.722 0.278 0.000
S32 Fracture of lumbar spine and pelvis
0.721 0.279 0.000
N20 Calculus of kidney and ureter
0.721 0.279 0.000
T42.4 Benzodiazepines
0.719 0.281 0.000
I60 Subarachnoid haemorrhage
0.719 0.281 0.000
M18 Arthrosis of first carpometacarpal joint
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.716 0.284 0.000
E14.9 Without complications
0.715 0.285 0.000
J18 Pneumonia, organism unspecified
0.714 0.286 0.000
E66.9 Obesity, unspecified
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
M15 Polyarthrosis
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
M17.5 Other secondary gonarthrosis
0.712 0.287 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.712 0.287 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.712 0.287 0.000
M23.5 Chronic instability of knee
0.712 0.288 0.000
E87.3 Alkalosis
0.709 0.291 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.709 0.291 0.000
N48 Other disorders of penis
0.708 0.292 0.000
I67 Other cerebrovascular diseases
0.708 0.292 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
I27.9 Pulmonary heart disease, unspecified
0.707 0.293 0.000
J94 Other pleural conditions
0.706 0.294 0.000
N25-N29 Other disorders of kidney and ureter
0.704 0.296 0.000
N39 Other disorders of urinary system
0.704 0.296 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
I28 Other diseases of pulmonary vessels
0.703 0.297 0.000
K92 Other diseases of digestive system
0.703 0.297 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.702 0.298 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.702 0.298 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M33 Dermatopolymyositis
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M30 Polyarteritis nodosa and related conditions
0.699 0.301 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.698 0.302 0.000
M34 Systemic sclerosis
0.698 0.302 0.000
J10 Influenza due to identified influenza virus
0.698 0.302 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.697 0.302 0.000
F60-F69 Disorders of adult personality and behaviour
0.697 0.303 0.000
M50-M54 Other dorsopathies
0.697 0.303 0.000
M43 Other deforming dorsopathies
0.697 0.303 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.696 0.304 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.696 0.304 0.000
K76.8 Other specified diseases of liver
0.696 0.304 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.694 0.306 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.694 0.306 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.694 0.306 0.000
O45 Premature separation of placenta [abruptio placentae]
0.693 0.307 0.000
O41 Other disorders of amniotic fluid and membranes
0.693 0.307 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.693 0.307 0.000
O33 Maternal care for known or suspected disproportion
0.693 0.307 0.000
O31 Complications specific to multiple gestation
0.693 0.307 0.000
O30 Multiple gestation
0.693 0.307 0.000
O40 Polyhydramnios
0.693 0.307 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.693 0.307 0.000
E85 Amyloidosis
0.691 0.309 0.000
E84 Cystic fibrosis
0.691 0.309 0.000
E79 Disorders of purine and pyrimidine metabolism
0.691 0.309 0.000
E77 Disorders of glycoprotein metabolism
0.691 0.309 0.000
E76 Disorders of glycosaminoglycan metabolism
0.691 0.309 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
E72 Other disorders of amino-acid metabolism
0.691 0.309 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.691 0.309 0.000
E70 Disorders of aromatic amino-acid metabolism
0.691 0.309 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.691 0.309 0.000
E66.8 Other obesity
0.691 0.309 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.690 0.310 0.000
M79.64 Pain in limb (Hand)
0.689 0.311 0.000
M23.9 Internal derangement of knee, unspecified
0.689 0.311 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.689 0.311 0.000
M23.1 Discoid meniscus (congenital)
0.689 0.311 0.000
M23.0 Cystic meniscus
0.689 0.311 0.000
I15 Secondary hypertension
0.687 0.313 0.000
I13 Hypertensive heart and renal disease
0.687 0.313 0.000
F99-F99 Unspecified mental disorder
0.687 0.313 0.000
L10-L14 Bullous disorders
0.687 0.313 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.686 0.313 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.684 0.316 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.684 0.316 0.000
J92 Pleural plaque
0.684 0.316 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.684 0.316 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.683 0.317 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
L28.0 Lichen simplex chronicus
0.681 0.319 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.681 0.319 0.000
J95-J99 Other diseases of the respiratory system
0.681 0.319 0.000
M23.37 Other meniscus derangements-Capsular lig
0.680 0.320 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.680 0.320 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.680 0.320 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.680 0.320 0.000
I11 Hypertensive heart disease
0.679 0.321 0.000
I12 Hypertensive renal disease
0.679 0.321 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.678 0.322 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.678 0.322 0.000
J20 Acute bronchitis
0.677 0.323 0.000
M35 Other systemic involvement of connective tissue
0.677 0.323 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.677 0.323 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.676 0.324 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.676 0.324 0.000
M22 Disorders of patella
0.675 0.325 0.000
O29 Complications of anaesthesia during pregnancy
0.674 0.326 0.000
O28 Abnormal findings on antenatal screening of mother
0.674 0.326 0.000
O24 Diabetes mellitus in pregnancy
0.674 0.326 0.000
O23 Infections of genito-urinary tract in pregnancy
0.674 0.326 0.000
O22 Venous complications in pregnancy
0.674 0.326 0.000
O21 Excessive vomiting in pregnancy
0.674 0.326 0.000
O25 Malnutrition in pregnancy
0.674 0.326 0.000
I27.2 Other secondary pulmonary hypertension
0.674 0.326 0.000
I85.9 Oesophageal varices without bleeding
0.672 0.328 0.000
N42.0 Calculus of prostate
0.671 0.328 0.000
E13 Other specified diabetes mellitus
0.671 0.329 0.000
I82 Other venous embolism and thrombosis
0.670 0.330 0.000
O15 Eclampsia
0.670 0.330 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.670 0.330 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.670 0.330 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.670 0.330 0.000
E07 Other disorders of thyroid
0.670 0.330 0.000
I20.9 Angina pectoris, unspecified
0.669 0.331 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.669 0.331 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.669 0.331 0.000
E87.4 Mixed disorder of acid-base balance
0.669 0.331 0.000
N19 Unspecified renal failure
0.668 0.332 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.668 0.332 0.000
M66 Spontaneous rupture of synovium and tendon
0.668 0.332 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.667 0.332 0.000
F70-F79 Mental retardation
0.667 0.332 0.000
N43.3 Hydrocele, unspecified
0.667 0.333 0.000
K76.6 Portal hypertension
0.667 0.333 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.665 0.335 0.000
N41 Inflammatory diseases of prostate
0.665 0.335 0.000
M23.49 Loose body in knee-Unspec lig/men
0.664 0.336 0.000
K13 Other diseases of lip and oral mucosa
0.664 0.336 0.000
L25 Unspecified contact dermatitis
0.664 0.336 0.000
L24 Irritant contact dermatitis
0.664 0.336 0.000
L23 Allergic contact dermatitis
0.664 0.336 0.000
L21 Seborrhoeic dermatitis
0.664 0.336 0.000
L20 Atopic dermatitis
0.664 0.336 0.000
L26 Exfoliative dermatitis
0.664 0.336 0.000
L22 Diaper [napkin] dermatitis
0.664 0.336 0.000
M77 Other enthesopathies
0.663 0.337 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
M79.60 Pain in limb (Multiple sites)
0.661 0.339 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.661 0.339 0.000
T43.9 Psychotropic drug, unspecified
0.660 0.340 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
T43.6 Psychostimulants with abuse potential
0.660 0.340 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.660 0.340 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.660 0.340 0.000
N75 Diseases of Bartholin's gland
0.660 0.340 0.000
K02 Dental caries
0.660 0.340 0.000
G91 Hydrocephalus
0.659 0.341 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.658 0.342 0.000
L29.0 Pruritus ani
0.658 0.342 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.658 0.342 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.657 0.343 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.657 0.343 0.000
L82 Seborrhoeic keratosis
0.656 0.344 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.655 0.344 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.654 0.346 0.000
N39.3 Stress incontinence
0.654 0.346 0.000
I62 Other nontraumatic intracranial haemorrhage
0.654 0.346 0.000
W19.9 Unspecified place
0.653 0.347 0.000
K92.0 Haematemesis
0.653 0.347 0.000
T43.2 Other and unspecified antidepressants
0.652 0.348 0.000
L90 Atrophic disorders of skin
0.652 0.348 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.651 0.349 0.000
I87 Other disorders of veins
0.650 0.350 0.000
M79.9 Soft tissue disorder, unspecified
0.649 0.351 0.000
M79.5 Residual foreign body in soft tissue
0.649 0.351 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.649 0.351 0.000
M79.3 Panniculitis, unspecified
0.649 0.351 0.000
M79.2 Neuralgia and neuritis, unspecified
0.649 0.351 0.000
M79.1 Myalgia
0.649 0.351 0.000
I27.8 Other specified pulmonary heart diseases
0.647 0.353 0.000
I27.1 Kyphoscoliotic heart disease
0.647 0.353 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.647 0.353 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.647 0.353 0.000
K11 Diseases of salivary glands
0.647 0.353 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.646 0.354 0.000
S20-S29 Injuries to the thorax
0.645 0.354 0.000
N30 Cystitis
0.645 0.355 0.000
L71 Rosacea
0.645 0.355 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.644 0.356 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.643 0.357 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.642 0.357 0.000
N46 Male infertility
0.642 0.357 0.000
N44 Torsion of testis
0.642 0.357 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.642 0.358 0.000
O14.0 Moderate preeclampsia
0.642 0.358 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.642 0.358 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.642 0.358 0.000
K12 Stomatitis and related lesions
0.641 0.359 0.000
K09 Cysts of oral region, not elsewhere classified
0.641 0.359 0.000
E78.0 Pure hypercholesterolaemia
0.640 0.360 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.640 0.360 0.000
E50-E64 Other nutritional deficiencies
0.639 0.361 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.638 0.362 0.000
F32.9 Depressive episode, unspecified
0.638 0.362 0.000
E03 Other hypothyroidism
0.638 0.362 0.000
E67 Other hyperalimentation
0.637 0.363 0.000
E68 Sequelae of hyperalimentation
0.637 0.363 0.000
E65 Localised adiposity
0.637 0.363 0.000
N45 Orchitis and epididymitis
0.636 0.364 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.636 0.364 0.000
O20.8 Other haemorrhage in early pregnancy
0.635 0.365 0.000
M79.62 Pain in limb (Upper arm)
0.635 0.365 0.000
E89.3 Postprocedural hypopituitarism
0.635 0.365 0.000
Y43 Primarily systemic agents
0.634 0.366 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.634 0.366 0.000
I81 Portal vein thrombosis
0.633 0.367 0.000
G81 Hemiplegia
0.633 0.367 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.632 0.367 0.000
E83.3 Disorders of phosphorus metabolism
0.632 0.368 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.632 0.368 0.000
S42 Fracture of shoulder and upper arm
0.632 0.368 0.000
N11 Chronic tubulo-interstitial nephritis
0.629 0.370 0.000
G30-G32 Other degenerative diseases of the nervous system
0.629 0.370 0.000
N13 Obstructive and reflux uropathy
0.629 0.371 0.000
N99-N99 Other disorders of the genitourinary system
0.629 0.371 0.000
O26.8 Other specified pregnancy-related conditions
0.628 0.372 0.000
Y35-Y36 Legal intervention and operations of war
0.628 0.372 0.000
Y10-Y34 Event of undetermined intent
0.628 0.372 0.000
Y00-Y09 Assault
0.628 0.372 0.000
X85-X99 Assault
0.628 0.372 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.628 0.372 0.000
X50-X57 Overexertion, travel and privation
0.628 0.372 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.628 0.372 0.000
X30-X39 Exposure to forces of nature
0.628 0.372 0.000
X20-X29 Contact with venomous animals and plants
0.628 0.372 0.000
X10-X19 Contact with heat and hot substances
0.628 0.372 0.000
X00-X09 Exposure to smoke, fire and flames
0.628 0.372 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.628 0.372 0.000
W75-W84 Other accidental threats to breathing
0.628 0.372 0.000
W65-W74 Accidental drowning and submersion
0.628 0.372 0.000
W50-W64 Exposure to animate mechanical forces
0.628 0.372 0.000
V98-V99 Other and unspecified transport accidents
0.628 0.372 0.000
V95-V97 Air and space transport accidents
0.628 0.372 0.000
V90-V94 Water transport accidents
0.628 0.372 0.000
V80-V89 Other land transport accidents
0.628 0.372 0.000
V70-V79 Bus occupant injured in transport accident
0.628 0.372 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.628 0.372 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.628 0.372 0.000
V40-V49 Car occupant injured in transport accident
0.628 0.372 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.628 0.372 0.000
V01-V09 Pedestrian injured in transport accident
0.628 0.372 0.000
O43.8 Other placental disorders
0.628 0.372 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.628 0.372 0.000
L27.8 Dermatitis due to other substances taken internally
0.628 0.372 0.000
L27.2 Dermatitis due to ingested food
0.628 0.372 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.628 0.372 0.000
N71 Inflammatory disease of uterus, except cervix
0.627 0.373 0.000
M79.61 Pain in limb (Shoulder region)
0.626 0.374 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.625 0.375 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.624 0.376 0.000
N10 Acute tubulo-interstitial nephritis
0.624 0.376 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.623 0.377 0.000
G90 Disorders of autonomic nervous system
0.623 0.377 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.623 0.377 0.000
G92 Toxic encephalopathy
0.623 0.377 0.000
M24.1 Other articular cartilage disorders
0.623 0.377 0.000
N20.1 Calculus of ureter
0.622 0.378 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.622 0.378 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.622 0.378 0.000
M70.4 Prepatellar bursitis
0.621 0.379 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.621 0.379 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.620 0.380 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.620 0.380 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.620 0.380 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.619 0.381 0.000
G72 Other myopathies
0.619 0.381 0.000
O80 Single spontaneous delivery
0.619 0.381 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.618 0.382 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.618 0.382 0.000
I88 Nonspecific lymphadenitis
0.618 0.382 0.000
I86 Varicose veins of other sites
0.618 0.382 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.618 0.382 0.000
S00-S09 Injuries to the head
0.618 0.382 0.000
M76.67 Achilles tendinitis (Ankle and foot)
0.617 0.383 0.000
T66-T78 Other and unspecified effects of external causes
0.615 0.384 0.000
M45 Ankylosing spondylitis
0.615 0.385 0.000
L40-L45 Papulosquamous disorders
0.615 0.385 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.614 0.386 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.614 0.386 0.000
T46.7 Peripheral vasodilators
0.614 0.386 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.614 0.386 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.614 0.386 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.614 0.386 0.000
T46.1 Calcium-channel blockers
0.614 0.386 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.614 0.386 0.000
M92 Other juvenile osteochondrosis
0.614 0.386 0.000
G57 Mononeuropathies of lower limb
0.614 0.386 0.000
F38 Other mood [affective] disorders
0.613 0.387 0.000
F34 Persistent mood [affective] disorders
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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