TreeWAS – Variant ID: rs766092

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.623	0.377
E10.9 Without complications	0.000	0.626	0.374
E10.4 With neurological complications	0.000	0.649	0.350
E10.5 With peripheral circulatory complications	0.000	0.655	0.345
E10.6 With other specified complications	0.000	0.660	0.340
E10.8 With unspecified complications	0.000	0.682	0.318
K90 Intestinal malabsorption	0.000	0.686	0.314
E10.1 With ketoacidosis	0.000	0.717	0.283
E10.2 With renal complications	0.000	0.718	0.282
E10-E14 Diabetes mellitus	0.000	0.720	0.280
E10.7 With multiple complications	0.000	0.729	0.271
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.741	0.259
E83 Disorders of mineral metabolism	0.000	0.742	0.258
E10.0 With coma	0.000	0.744	0.256
E10.3 With ophthalmic complications	0.000	0.756	0.244
E13 Other specified diabetes mellitus	0.000	0.763	0.237
K90.3 Pancreatic steatorrhoea	0.000	0.774	0.225
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.774	0.225
K90.1 Tropical sprue	0.000	0.774	0.225
K90.8 Other intestinal malabsorption	0.000	0.783	0.217
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.791	0.209
E13.9 Without complications	0.000	0.792	0.208
E70-E90 Metabolic disorders	0.000	0.792	0.208
E14 Unspecified diabetes mellitus	0.000	0.796	0.204
E12 Malnutrition-related diabetes mellitus	0.000	0.799	0.201
E14.3 With ophthalmic complications	0.000	0.806	0.194
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.815	0.185
E83.8 Other disorders of mineral metabolism	0.000	0.815	0.185
E83.2 Disorders of zinc metabolism	0.000	0.815	0.185
E83.0 Disorders of copper metabolism	0.000	0.815	0.185
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.820	0.180
E85 Amyloidosis	0.000	0.823	0.177
E88 Other metabolic disorders	0.000	0.824	0.176
E40-E46 Malnutrition	0.000	0.826	0.174
E13.8 With unspecified complications	0.000	0.830	0.170
E13.7 With multiple complications	0.000	0.830	0.170
E13.6 With other specified complications	0.000	0.830	0.170
E13.5 With peripheral circulatory complications	0.000	0.830	0.170
E13.4 With neurological complications	0.000	0.830	0.170
E13.2 With renal complications	0.000	0.830	0.170
E13.1 With ketoacidosis	0.000	0.830	0.170
E13.0 With coma	0.000	0.830	0.170
E13.3 With ophthalmic complications	0.000	0.834	0.166
E16 Other disorders of pancreatic internal secretion	0.000	0.841	0.159
E85.9 Amyloidosis, unspecified	0.000	0.847	0.153
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.847	0.153
E14.5 With peripheral circulatory complications	0.000	0.848	0.152
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.850	0.150
E84 Cystic fibrosis	0.000	0.850	0.149
E77 Disorders of glycoprotein metabolism	0.000	0.850	0.149
E76 Disorders of glycosaminoglycan metabolism	0.000	0.850	0.149
E72 Other disorders of amino-acid metabolism	0.000	0.850	0.149
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.850	0.149
E70 Disorders of aromatic amino-acid metabolism	0.000	0.850	0.149
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.850	0.149
E16.2 Hypoglycaemia, unspecified	0.000	0.851	0.149
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.851	0.149
E46 Unspecified protein-energy malnutrition	0.000	0.852	0.148
E14.7 With multiple complications	0.000	0.854	0.146
E14.6 With other specified complications	0.000	0.854	0.146
E14.2 Withrenal complications	0.000	0.854	0.146
E14.0 With coma	0.000	0.854	0.146
E12.9 Without complications	0.000	0.856	0.144
E12.8 With unspecified complications	0.000	0.856	0.144
E12.7 With multiple complications	0.000	0.856	0.144
E12.6 With other specified complications	0.000	0.856	0.144
E12.5 With peripheral circulatory complications	0.000	0.856	0.144
E12.4 With neurological complications	0.000	0.856	0.144
E12.3 With ophthalmic complications	0.000	0.856	0.144
E12.2 With renal complications	0.000	0.856	0.144
E12.1 With ketoacidosis	0.000	0.856	0.144
E12.0 With coma	0.000	0.856	0.144
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.856	0.144
E65-E68 Obesity and other hyperalimentation	0.000	0.858	0.142
E14.4 With neurological complications	0.000	0.859	0.141
E79 Disorders of purine and pyrimidine metabolism	0.000	0.864	0.135
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.866	0.134
E88.8 Other specified metabolic disorders	0.000	0.866	0.134
E85.4 Organ-limited amyloidosis	0.000	0.867	0.133
E88.2 Lipomatosis, not elsewhere classified	0.000	0.867	0.133
E11 Non-insulin-dependent diabetes mellitus	0.000	0.870	0.130
E15 Nondiabetic hypoglycaemic coma	0.000	0.871	0.129
E88.3 Tumour lysis syndrome	0.000	0.873	0.127
E85.8 Other amyloidosis	0.000	0.873	0.127
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.873	0.127
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.873	0.127
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.873	0.127
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.875	0.125
E45 Retarded development following protein-energy malnutrition	0.000	0.875	0.125
E43 Unspecified severe protein-energy malnutrition	0.000	0.875	0.125
E42 Marasmic kwashiorkor	0.000	0.875	0.125
E41 Nutritional marasmus	0.000	0.875	0.125
E40 Kwashiorkor	0.000	0.875	0.125
E14.1 With ketoacidosis	0.000	0.879	0.121
E65 Localised adiposity	0.000	0.879	0.121
E85.3 Secondary systemic amyloidosis	0.000	0.879	0.121
E14.8 With unspecified complications	0.000	0.879	0.121
E89.2 Postprocedural hypoparathyroidism	0.000	0.879	0.121
E74 Other disorders of carbohydrate metabolism	0.000	0.882	0.118
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.882	0.118
E88.9 Metabolic disorder, unspecified	0.000	0.882	0.117
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.884	0.116
E80.4 Gilbert's syndrome	0.000	0.886	0.114
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.886	0.114
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.886	0.114
E16.4 Abnormal secretion of gastrin	0.000	0.886	0.114
E16.3 Increased secretion of glucagon	0.000	0.886	0.114
E75.5 Other lipid storage disorders	0.000	0.887	0.113
E89.4 Postprocedural ovarian failure	0.000	0.888	0.112
E83.3 Disorders of phosphorus metabolism	0.000	0.888	0.112
E83.4 Disorders of magnesium metabolism	0.000	0.889	0.111
E75.6 Lipid storage disorder, unspecified	0.000	0.890	0.109
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.890	0.109
E75.3 Sphingolipidosis, unspecified	0.000	0.890	0.109
E75.2 Other sphingolipidosis	0.000	0.890	0.109
E75.1 Other gangliosidosis	0.000	0.890	0.109
E75.0 GM2 gangliosidosis	0.000	0.890	0.109
E73 Lactose intolerance	0.000	0.891	0.109
E11.5 With peripheral circulatory complications	0.000	0.891	0.109
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.892	0.108
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.892	0.108
E89.5 Postprocedural testicular hypofunction	0.000	0.892	0.108
E89.1 Postprocedural hypoinsulinaemia	0.000	0.892	0.108
E89.0 Postprocedural hypothyroidism	0.000	0.892	0.108
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.893	0.107
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.893	0.107
E70.3 Albinism	0.000	0.893	0.107
E70.2 Disorders of tyrosine metabolism	0.000	0.893	0.107
E70.1 Other hyperphenylalaninaemias	0.000	0.893	0.107
E70.0 Classical phenylketonuria	0.000	0.893	0.107
E71.3 Disorders of fatty-acid metabolism	0.000	0.893	0.107
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.893	0.107
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.893	0.107
E71.0 Maple-syrup-urine disease	0.000	0.893	0.107
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.893	0.107
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.893	0.107
E72.5 Disorders of glycine metabolism	0.000	0.893	0.107
E72.4 Disorders of ornithine metabolism	0.000	0.893	0.107
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.893	0.107
E72.2 Disorders of urea cycle metabolism	0.000	0.893	0.107
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.893	0.107
E72.0 Disorders of amino-acid transport	0.000	0.893	0.107
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.893	0.107
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.893	0.107
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.893	0.107
E76.2 Other mucopolysaccharidoses	0.000	0.893	0.107
E76.1 Mucopolysaccharidosis, type II	0.000	0.893	0.107
E76.0 Mucopolysaccharidosis, type I	0.000	0.893	0.107
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.893	0.107
E77.8 Other disorders of glycoprotein metabolism	0.000	0.893	0.107
E77.1 Defects in glycoprotein degradation	0.000	0.893	0.107
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.893	0.107
E84.9 Cystic fibrosis, unspecified	0.000	0.893	0.107
E84.8 Cystic fibrosis with other manifestations	0.000	0.893	0.107
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.893	0.107
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.893	0.107
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.893	0.107
E80.5 Crigler-Najjar syndrome	0.000	0.893	0.107
E80.3 Defects of catalase and peroxydase	0.000	0.893	0.107
E80.1 Porphyria cutanea tarda	0.000	0.893	0.107
E80.0 Hereditary erythropoietic porphyria	0.000	0.893	0.107
E80.2 Other porphyria	0.000	0.897	0.103
E80.6 Other disorders of bilirubin metabolism	0.000	0.898	0.102
E67 Other hyperalimentation	0.000	0.898	0.102
E68 Sequelae of hyperalimentation	0.000	0.898	0.102
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.899	0.101
E11.0 With coma	0.000	0.900	0.100
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.901	0.099
K90.9 Intestinal malabsorption, unspecified	0.001	0.902	0.097
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.903	0.097
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.903	0.097
E79.1 Lesch-Nyhan syndrome	0.000	0.903	0.097
E11.8 With unspecified complications	0.000	0.903	0.097
E11.1 With ketoacidosis	0.000	0.906	0.094
E11.7 With multiple complications	0.000	0.907	0.093
E11.2 With renal complications	0.000	0.907	0.093
E44.1 Mild protein-energy malnutrition	0.000	0.910	0.089
E44.0 Moderate protein-energy malnutrition	0.000	0.910	0.089
E11.4 With neurological complications	0.000	0.910	0.090
E11.6 With other specified complications	0.000	0.911	0.089
E16.1 Other hypoglycaemia	0.000	0.913	0.086
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.915	0.085
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.915	0.085
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.915	0.085
E74.2 Disorders of galactose metabolism	0.000	0.915	0.085
E74.1 Disorders of fructose metabolism	0.000	0.915	0.085
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.917	0.083
E78.4 Other hyperlipidaemia	0.000	0.918	0.082
E00-E07 Disorders of thyroid gland	0.000	0.919	0.081
E73.8 Other lactose intolerance	0.000	0.921	0.078
E73.1 Secondary lactase deficiency	0.000	0.921	0.078
E73.0 Congenital lactase deficiency	0.000	0.921	0.078
E74.0 Glycogen storage disease	0.000	0.922	0.078
E78.6 Lipoprotein deficiency	0.000	0.923	0.077
E67.8 Other specified hyperalimentation	0.000	0.927	0.073
E67.3 Hypervitaminosis D	0.000	0.927	0.073
E67.2 Megavitamin-B6 syndrome	0.000	0.927	0.073
E67.1 Hypercarotenaemia	0.000	0.927	0.073
E67.0 Hypervitaminosis A	0.000	0.927	0.073
E78.3 Hyperchylomicronaemia	0.000	0.927	0.073
E50-E64 Other nutritional deficiencies	0.000	0.929	0.071
E78.1 Pure hyperglyceridaemia	0.000	0.931	0.069
E11.3 With ophthalmic complications	0.000	0.932	0.068
E83.5 Disorders of calcium metabolism	0.000	0.934	0.066
E89.3 Postprocedural hypopituitarism	0.000	0.935	0.065
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.935	0.064
E78.2 Mixed hyperlipidaemia	0.000	0.936	0.064
E07 Other disorders of thyroid	0.000	0.937	0.063
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.939	0.061
E20-E35 Disorders of other endocrine glands	0.000	0.940	0.060
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.942	0.058
E00 Congenital iodine-deficiency syndrome	0.000	0.942	0.058
E04 Other non-toxic goitre	0.000	0.943	0.057
E87.3 Alkalosis	0.000	0.944	0.056
E06 Thyroiditis	0.000	0.945	0.055
E14.9 Without complications	0.000	0.945	0.055
E03 Other hypothyroidism	0.000	0.947	0.053
E07.9 Disorder of thyroid, unspecified	0.000	0.947	0.053
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.949	0.051
E63 Other nutritional deficiencies	0.000	0.949	0.051
E56 Other vitamin deficiencies	0.000	0.949	0.051
E50 Vitamin A deficiency	0.000	0.949	0.051
E60 Dietary zinc deficiency	0.000	0.949	0.051
E59 Dietary selenium deficiency	0.000	0.949	0.051
E54 Ascorbic acid deficiency	0.000	0.949	0.051
E52 Niacin deficiency [pellagra]	0.000	0.949	0.051
E58 Dietary calcium deficiency	0.000	0.949	0.050
E87.0 Hyperosmolality and hypernatraemia	0.000	0.950	0.050
E04.9 Non-toxic goitre, unspecified	0.000	0.950	0.050
E51 Thiamine deficiency	0.000	0.951	0.049
E66 Obesity	0.000	0.951	0.049
E03.8 Other specified hypothyroidism	0.000	0.952	0.048
E28 Ovarian dysfunction	0.000	0.954	0.046
E20 Hypoparathyroidism	0.000	0.954	0.046
E53 Deficiency of other B group vitamins	0.000	0.955	0.045
E07.1 Dyshormogenetic goitre	0.000	0.955	0.045
E07.0 Hypersecretion of calcitonin	0.000	0.955	0.045
E26 Hyperaldosteronism	0.000	0.955	0.045
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.955	0.044
E87.7 Fluid overload	0.000	0.956	0.044
E87.4 Mixed disorder of acid-base balance	0.000	0.956	0.044
E29 Testicular dysfunction	0.000	0.956	0.044
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.957	0.043
E32 Diseases of thymus	0.000	0.957	0.043
E31 Polyglandular dysfunction	0.000	0.957	0.043
E30 Disorders of puberty, not elsewhere classified	0.000	0.957	0.043
E25 Adrenogenital disorders	0.000	0.957	0.043
E04.0 Non-toxic diffuse goitre	0.000	0.957	0.043
E23 Hypofunction and other disorders of pituitary gland	0.000	0.957	0.043
E78.8 Other disorders of lipoprotein metabolism	0.000	0.958	0.042
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.958	0.042
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.958	0.042
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.958	0.042
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.958	0.042
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.958	0.042
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.958	0.042
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.958	0.042
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.958	0.042
E87.2 Acidosis	0.000	0.958	0.042
E06.3 Autoimmune thyroiditis	0.000	0.959	0.041
E28.2 Polycystic ovarian syndrome	0.000	0.959	0.041
E04.8 Other specified non-toxic goitre	0.000	0.959	0.041
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.959	0.041
E06.5 Other chronic thyroiditis	0.000	0.960	0.040
E06.4 Drug-induced thyroiditis	0.000	0.960	0.040
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.960	0.040
E06.1 Subacute thyroiditis	0.000	0.960	0.040
E06.0 Acute thyroiditis	0.000	0.960	0.040
E23.2 Diabetes insipidus	0.000	0.960	0.040
E34 Other endocrine disorders	0.000	0.960	0.039
E24 Cushing's syndrome	0.000	0.961	0.039
E55 Vitamin D deficiency	0.000	0.961	0.039
E03.5 Myxoedema coma	0.000	0.962	0.038
E03.4 Atrophy of thyroid (acquired)	0.000	0.962	0.038
E03.3 Postinfectious hypothyroidism	0.000	0.962	0.038
E03.1 Congenital hypothyroidism without goitre	0.000	0.962	0.038
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.962	0.038
E73.9 Lactose intolerance, unspecified	0.001	0.962	0.037
E07.8 Other specified disorders of thyroid	0.000	0.962	0.038
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.962	0.038
E50.9 Vitamin A deficiency, unspecified	0.000	0.963	0.037
E50.8 Other manifestations of vitamin A deficiency	0.000	0.963	0.037
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.963	0.037
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.963	0.037
E50.5 Vitamin A deficiency with night blindness	0.000	0.963	0.037
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.963	0.037
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.963	0.037
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.963	0.037
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.963	0.037
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.963	0.037
E56.9 Vitamin deficiency, unspecified	0.000	0.963	0.037
E56.8 Deficiency of other vitamins	0.000	0.963	0.037
E56.1 Deficiency of vitamin K	0.000	0.963	0.037
E56.0 Deficiency of vitamin E	0.000	0.963	0.037
E63.9 Nutritional deficiency, unspecified	0.000	0.963	0.037
E63.8 Other specified nutritional deficiencies	0.000	0.963	0.037
E63.1 Imbalance of constituents of food intake	0.000	0.963	0.037
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.963	0.037
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.963	0.037
E64.8 Sequelae of other nutritional deficiencies	0.000	0.963	0.037
E64.3 Sequelae of rickets	0.000	0.963	0.037
E64.2 Sequelae of vitamin C deficiency	0.000	0.963	0.037
E64.1 Sequelae of vitamin A deficiency	0.000	0.963	0.037
E64.0 Sequelae of protein-energy malnutrition	0.000	0.963	0.037
E27 Other disorders of adrenal gland	0.000	0.963	0.037
E87.5 Hyperkalaemia	0.000	0.964	0.036
E20.9 Hypoparathyroidism, unspecified	0.000	0.964	0.036
E51.9 Thiamine deficiency, unspecified	0.000	0.964	0.035
E51.8 Other manifestations of thiamine deficiency	0.000	0.964	0.035
E51.1 Beriberi	0.000	0.964	0.035
E66.1 Drug-induced obesity	0.000	0.965	0.035
E06.9 Thyroiditis, unspecified	0.000	0.965	0.035
E27.1 Primary adrenocortical insufficiency	0.000	0.966	0.034
E04.2 Non-toxic multinodular goitre	0.000	0.966	0.034
E66.0 Obesity due to excess calories	0.000	0.966	0.034
E51.2 Wernicke's encephalopathy	0.000	0.966	0.033
E26.0 Primary hyperaldosteronism	0.000	0.966	0.034
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.967	0.033
E28.9 Ovarian dysfunction, unspecified	0.000	0.967	0.033
E28.8 Other ovarian dysfunction	0.000	0.967	0.033
E28.1 Androgen excess	0.000	0.967	0.033
E28.0 Oestrogen excess	0.000	0.967	0.033
E20.8 Other hypoparathyroidism	0.000	0.967	0.033
E20.1 Pseudohypoparathyroidism	0.000	0.967	0.033
E20.0 Idiopathic hypoparathyroidism	0.000	0.967	0.033
E24.2 Drug-induced Cushing's syndrome	0.000	0.967	0.033
E53.1 Pyridoxine deficiency	0.000	0.967	0.033
E53.0 Riboflavin deficiency	0.000	0.967	0.033
E26.9 Hyperaldosteronism, unspecified	0.000	0.968	0.032
E26.8 Other hyperaldosteronism	0.000	0.968	0.032
E26.1 Secondary hyperaldosteronism	0.000	0.968	0.032
E53.9 Vitamin B deficiency, unspecified	0.000	0.968	0.032
E29.1 Testicular hypofunction	0.000	0.968	0.032
E29.9 Testicular dysfunction, unspecified	0.000	0.968	0.031
E29.8 Other testicular dysfunction	0.000	0.968	0.031
E29.0 Testicular hyperfunction	0.000	0.968	0.031
E25.9 Adrenogenital disorder, unspecified	0.000	0.969	0.031
E25.8 Other adrenogenital disorders	0.000	0.969	0.031
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.969	0.031
E30.9 Disorder of puberty, unspecified	0.000	0.969	0.031
E30.8 Other disorders of puberty	0.000	0.969	0.031
E30.1 Precocious puberty	0.000	0.969	0.031
E30.0 Delayed puberty	0.000	0.969	0.031
E31.9 Polyglandular dysfunction, unspecified	0.000	0.969	0.031
E31.8 Other polyglandular dysfunction	0.000	0.969	0.031
E31.1 Polyglandular hyperfunction	0.000	0.969	0.031
E31.0 Autoimmune polyglandular failure	0.000	0.969	0.031
E32.9 Disease of thymus, unspecified	0.000	0.969	0.031
E32.8 Other diseases of thymus	0.000	0.969	0.031
E32.1 Abscess of thymus	0.000	0.969	0.031
E32.0 Persistent hyperplasia of thymus	0.000	0.969	0.031
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.969	0.031
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.969	0.031
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.969	0.031
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.969	0.031
E23.1 Drug-induced hypopituitarism	0.000	0.969	0.031
E23.7 Disorder of pituitary gland, unspecified	0.000	0.969	0.030
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.970	0.029
E34.5 Androgen resistance syndrome	0.000	0.971	0.028
E34.4 Constitutional tall stature	0.000	0.971	0.028
E34.3 Short stature, not elsewhere classified	0.000	0.971	0.028
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.971	0.028
E34.1 Other hypersecretion of intestinal hormones	0.000	0.971	0.028
E24.8 Other Cushing's syndrome	0.000	0.971	0.028
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.971	0.028
E24.3 Ectopic ACTH syndrome	0.000	0.971	0.028
E24.1 Nelson's syndrome	0.000	0.971	0.028
E55.0 Rickets, active	0.000	0.971	0.028
E34.9 Endocrine disorder, unspecified	0.000	0.972	0.028
E53.8 Deficiency of other specified B group vitamins	0.000	0.972	0.028
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.972	0.028
E34.8 Other specified endocrine disorders	0.000	0.972	0.028
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.973	0.027
E23.6 Other disorders of pituitary gland	0.000	0.973	0.027
E61 Deficiency of other nutrient elements	0.001	0.973	0.026
E04.1 Non-toxic single thyroid nodule	0.000	0.973	0.027
E27.5 Adrenomedullary hyperfunction	0.000	0.973	0.026
E27.0 Other adrenocortical overactivity	0.000	0.973	0.026
E34.0 Carcinoid syndrome	0.000	0.974	0.026
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.974	0.026
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.974	0.026
R31 Unspecified haematuria	0.026	0.974	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.974	0.025
E05.8 Other thyrotoxicosis	0.000	0.975	0.025
E05.5 Thyroid crisis or storm	0.000	0.976	0.024
E05.4 Thyrotoxicosis factitia	0.000	0.976	0.024
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.976	0.024
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.976	0.024
E86 Volume depletion	0.000	0.978	0.022
E28.3 Primary ovarian failure	0.001	0.979	0.020
E27.2 Addisonian crisis	0.000	0.979	0.020
E21.3 Hyperparathyroidism, unspecified	0.000	0.979	0.021
K90-K93 Other diseases of the digestive system	0.000	0.980	0.020
E21.4 Other specified disorders of parathyroid gland	0.000	0.980	0.020
E21.2 Other hyperparathyroidism	0.000	0.980	0.020
E24.9 Cushing's syndrome, unspecified	0.000	0.980	0.020
E61.9 Deficiency of nutrient element, unspecified	0.001	0.980	0.019
E61.8 Deficiency of other specified nutrient elements	0.001	0.980	0.019
E61.7 Deficiency of multiple nutrient elements	0.001	0.980	0.019
E61.6 Vanadium deficiency	0.001	0.980	0.019
E61.5 Molybdenum deficiency	0.001	0.980	0.019
E61.4 Chromium deficiency	0.001	0.980	0.019
E61.3 Manganese deficiency	0.001	0.980	0.019
E61.0 Copper deficiency	0.001	0.980	0.019
E22 Hyperfunction of pituitary gland	0.000	0.981	0.019
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.981	0.018
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.981	0.019
E27.8 Other specified disorders of adrenal gland	0.000	0.983	0.017
E55.9 Vitamin D deficiency, unspecified	0.000	0.983	0.017
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.984	0.016
E27.9 Disorder of adrenal gland, unspecified	0.000	0.984	0.015
E61.2 Magnesium deficiency	0.001	0.984	0.015
E23.0 Hypopituitarism	0.000	0.985	0.015
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.985	0.015
E66.9 Obesity, unspecified	0.000	0.986	0.014
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.986	0.014
E22.8 Other hyperfunction of pituitary gland	0.000	0.986	0.014
C71.2 Temporal lobe	0.014	0.986	0.000
C71 Malignant neoplasm of brain	0.013	0.987	0.000
C71.9 Brain, unspecified	0.013	0.987	0.000
E22.1 Hyperprolactinaemia	0.000	0.987	0.012
C71.3 Parietal lobe	0.011	0.989	0.000
E21.0 Primary hyperparathyroidism	0.000	0.989	0.011
C71.1 Frontal lobe	0.011	0.989	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.011
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.011
C71.7 Brain stem	0.010	0.990	0.000
C71.6 Cerebellum	0.010	0.990	0.000
C71.5 Cerebral ventricle	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
C71.8 Overlapping lesion of brain	0.009	0.990	0.000
M41.9 Scoliosis, unspecified	0.009	0.991	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.991	0.009
M41.96 Scoliosis, unspecified (Lumbar region)	0.009	0.991	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.009	0.991	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.009	0.991	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.009	0.991	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.992	0.008
C71.4 Occipital lobe	0.008	0.992	0.000
G44.2 Tension-type headache	0.008	0.992	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.992	0.008
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.008	0.992	0.000
E87.6 Hypokalaemia	0.000	0.993	0.007
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.993	0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.993	0.007
E61.1 Iron deficiency	0.001	0.993	0.006
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.007	0.993	0.000
G31.0 Circumscribed brain atrophy	0.000	0.993	0.007
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.007	0.993	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.007	0.993	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.007	0.993	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.007	0.993	0.000
E66.8 Other obesity	0.000	0.993	0.007
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.006	0.994	0.000
C69.9 Eye, unspecified	0.006	0.994	0.000
N04.9 Unspecified	0.000	0.994	0.006
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.005
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.994	0.000
C69.3 Choroid	0.005	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.004	0.995	0.000
C70.1 Spinal meninges	0.004	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
M41 Scoliosis	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.995	0.004
M22.2 Patellofemoral disorders	0.004	0.996	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.996	0.004
G30 Alzheimer's disease	0.000	0.996	0.004
C72.9 Central nervous system, unspecified	0.004	0.996	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.996	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.996	0.000
C72.4 Acoustic nerve	0.004	0.996	0.000
C72.3 Optic nerve	0.004	0.996	0.000
C72.2 Olfactory nerve	0.004	0.996	0.000
C72.1 Cauda equina	0.004	0.996	0.000
G44 Other headache syndromes	0.004	0.996	0.000
C72.0 Spinal cord	0.004	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.996	0.000
G44.8 Other specified headache syndromes	0.004	0.996	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.996	0.004
R52.1 Chronic intractable pain	0.004	0.996	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.996	0.004
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations