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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs769450
log Bayes Factor = 9.73216
Chromosome 19   position 45,410,444  (GRCh37) Explore rs769450 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F03 Unspecified dementia
0.000 0.000 1.000
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.000 1.000
F00 Dementia in Alzheimer's disease
0.000 0.000 1.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.000 0.001 0.999
F01 Vascular dementia
0.000 0.017 0.983
F01.9 Vascular dementia, unspecified
0.000 0.027 0.973
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.035 0.965
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.000 0.081 0.919
F05.9 Delirium, unspecified
0.000 0.081 0.919
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.000 0.095 0.905
F02 Dementia in other diseases classified elsewhere
0.000 0.132 0.868
F06.7 Mild cognitive disorder
0.000 0.160 0.840
G30.9 Alzheimer's disease, unspecified
0.000 0.171 0.829
G30 Alzheimer's disease
0.000 0.226 0.774
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.229 0.771
F05.0 Delirium not superimposed on dementia, so described
0.000 0.229 0.771
F00.1 Dementia in Alzheimer's disease with late onset
0.000 0.230 0.770
F02.8 Dementia in other specified diseases classified elsewhere
0.000 0.250 0.750
F05.8 Other delirium
0.000 0.254 0.746
F09 Unspecified organic or symptomatic mental disorder
0.000 0.283 0.717
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.000 0.283 0.717
F05.1 Delirium superimposed on dementia
0.000 0.287 0.713
G30.8 Other Alzheimer's disease
0.000 0.292 0.708
F01.8 Other vascular dementia
0.000 0.295 0.705
F01.3 Mixed cortical and subcortical vascular dementia
0.000 0.295 0.705
F01.2 Subcortical vascular dementia
0.000 0.295 0.705
F01.0 Vascular dementia of acute onset
0.000 0.295 0.705
F00.0 Dementia in Alzheimer's disease with early onset
0.000 0.297 0.703
F02.0 Dementia in Pick's disease
0.000 0.319 0.681
F01.1 Multi-infarct dementia
0.000 0.326 0.674
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.000 0.326 0.673
G30.0 Alzheimer's disease with early onset
0.000 0.335 0.665
F06.6 Organic emotionally labile [asthenic] disorder
0.000 0.351 0.649
F06.5 Organic dissociative disorder
0.000 0.351 0.649
F06.4 Organic anxiety disorder
0.000 0.351 0.649
F06.3 Organic mood [affective] disorders
0.000 0.351 0.649
F06.1 Organic catatonic disorder
0.000 0.351 0.649
F06.0 Organic hallucinosis
0.000 0.351 0.649
F06.2 Organic delusional [schizophrenia-like] disorder
0.000 0.364 0.636
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.000 0.371 0.629
G30.1 Alzheimer's disease with late onset
0.000 0.376 0.624
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.000 0.378 0.622
F02.2 Dementia in Huntington's disease
0.000 0.378 0.622
F02.1 Dementia in Creutzfeldt-Jakob disease
0.000 0.378 0.622
F02.3 Dementia in Parkinson's disease
0.000 0.392 0.608
F07.2 Postconcussional syndrome
0.000 0.397 0.603
F07.0 Organic personality disorder
0.000 0.441 0.559
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.000 0.447 0.553
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.447 0.553
F07.1 Postencephalitic syndrome
0.000 0.447 0.553
G30-G32 Other degenerative diseases of the nervous system
0.000 0.606 0.394
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.697 0.303
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.701 0.299
G31.0 Circumscribed brain atrophy
0.000 0.743 0.257
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.770 0.230
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.770 0.230
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.782 0.218
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.786 0.214
G31.8 Other specified degenerative diseases of nervous system
0.000 0.800 0.200
G31.2 Degeneration of nervous system due to alcohol
0.000 0.814 0.186
I49.3 Ventricular premature depolarisation
0.043 0.957 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.020 0.980 0.000
K22.4 Dyskinesia of oesophagus
0.000 0.984 0.016
D86.0 Sarcoidosis of lung
0.014 0.986 0.000
D86 Sarcoidosis
0.014 0.986 0.000
D86.9 Sarcoidosis, unspecified
0.013 0.987 0.000
D86.1 Sarcoidosis of lymph nodes
0.012 0.988 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.989 0.011
I67.2 Cerebral atherosclerosis
0.000 0.989 0.011
D86.3 Sarcoidosis of skin
0.010 0.989 0.000
D80-D89 Certain disorders involving the immune mechanism
0.010 0.990 0.000
N20.2 Calculus of kidney with calculus of ureter
0.010 0.990 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.010 0.990 0.000
F80.1 Expressive language disorder
0.000 0.990 0.010
I67 Other cerebrovascular diseases
0.000 0.990 0.010
D80 Immunodeficiency with predominantly antibody defects
0.010 0.990 0.000
D83 Common variable immunodeficiency
0.009 0.991 0.000
Chapter V Mental and behavioural disorders
0.000 0.991 0.009
I67.1 Cerebral aneurysm, nonruptured
0.000 0.991 0.009
R68.8 Other specified general symptoms and signs
0.009 0.991 0.000
F80 Specific developmental disorders of speech and language
0.000 0.991 0.009
D83.9 Common variable immunodeficiency, unspecified
0.009 0.991 0.000
D86.8 Sarcoidosis of other and combined sites
0.009 0.991 0.000
F80-F89 Disorders of psychological development
0.000 0.991 0.009
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.991 0.009
R61.9 Hyperhidrosis, unspecified
0.009 0.991 0.000
D82 Immunodeficiency associated with other major defects
0.008 0.992 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.008 0.992 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.008 0.992 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.008 0.992 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.008 0.992 0.000
D81 Combined immunodeficiencies
0.008 0.992 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.993 0.007
I67.5 Moyamoya disease
0.000 0.993 0.007
I67.4 Hypertensive encephalopathy
0.000 0.993 0.007
I67.3 Progressive vascular leukoencephalopathy
0.000 0.993 0.007
D80.8 Other immunodeficiencies with predominantly antibody defects
0.007 0.993 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.007 0.993 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.007 0.993 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.007 0.993 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.007 0.993 0.000
K90.0 Coeliac disease
0.007 0.993 0.000
D83.8 Other common variable immunodeficiencies
0.007 0.993 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.007 0.993 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.007 0.993 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.007 0.993 0.000
D82.1 Di George's syndrome
0.007 0.993 0.000
F70-F79 Mental retardation
0.000 0.993 0.007
F80.9 Developmental disorder of speech and language, unspecified
0.000 0.993 0.007
F80.8 Other developmental disorders of speech and language
0.000 0.993 0.007
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]
0.000 0.993 0.007
F80.0 Specific speech articulation disorder
0.000 0.993 0.007
F99-F99 Unspecified mental disorder
0.000 0.993 0.007
D80.1 Nonfamilial hypogammaglobulinaemia
0.007 0.993 0.000
F89 Unspecified disorder of psychological development
0.000 0.993 0.006
F88 Other disorders of psychological development
0.000 0.993 0.006
F83 Mixed specific developmental disorders
0.000 0.993 0.006
F82 Specific developmental disorder of motor function
0.000 0.993 0.006
F84 Pervasive developmental disorders
0.000 0.993 0.006
D84 Other immunodeficiencies
0.006 0.994 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.006 0.994 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.006 0.994 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.006 0.994 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.006 0.994 0.000
D82.2 Immunodeficiency with short-limbed stature
0.006 0.994 0.000
D82.0 Wiskott-Aldrich syndrome
0.006 0.994 0.000
E27.1 Primary adrenocortical insufficiency
0.006 0.994 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.006 0.994 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.994 0.006
F80.2 Receptive language disorder
0.000 0.994 0.006
R79.8 Other specified abnormal findings of blood chemistry
0.006 0.994 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.994 0.006
D81.9 Combined immunodeficiency, unspecified
0.006 0.994 0.000
D81.8 Other combined immunodeficiencies
0.006 0.994 0.000
D81.7 Major histocompatibility complex class II deficiency
0.006 0.994 0.000
D81.6 Major histocompatibility complex class I deficiency
0.006 0.994 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.006 0.994 0.000
D81.4 Nezelof's syndrome
0.006 0.994 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.006 0.994 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.006 0.994 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.006 0.994 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.006 0.994 0.000
F81 Specific developmental disorders of scholastic skills
0.000 0.994 0.005
R72 Abnormality of white blood cells, not elsewhere classified
0.006 0.994 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.995 0.005
R68 Other general symptoms and signs
0.005 0.995 0.000
R61 Hyperhidrosis
0.005 0.995 0.000
F84.0 Childhood autism
0.000 0.995 0.005
F29 Unspecified nonorganic psychosis
0.000 0.995 0.005
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.005 0.995 0.000
F78 Other mental retardation
0.000 0.995 0.005
F73 Profound mental retardation
0.000 0.995 0.005
F72 Severe mental retardation
0.000 0.995 0.005
F71 Moderate mental retardation
0.000 0.995 0.005
F70 Mild mental retardation
0.000 0.995 0.005
F84.9 Pervasive developmental disorder, unspecified
0.000 0.995 0.005
F84.8 Other pervasive developmental disorders
0.000 0.995 0.005
F84.4 Overactive disorder associated with mental retardation and stereotyped movements
0.000 0.995 0.005
F84.3 Other childhood disintegrative disorder
0.000 0.995 0.005
F84.2 Rett's syndrome
0.000 0.995 0.005
F84.1 Atypical autism
0.000 0.995 0.005
R61.0 Localised hyperhidrosis
0.005 0.995 0.000
F79 Unspecified mental retardation
0.000 0.995 0.005
D89.9 Disorder involving the immune mechanism, unspecified
0.005 0.995 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.005 0.995 0.000
D84.8 Other specified immunodeficiencies
0.005 0.995 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.005 0.995 0.000
D89.3 Immune reconstitution syndrome
0.005 0.995 0.000
D89.1 Cryoglobulinaemia
0.005 0.995 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.005 0.995 0.000
F99 Mental disorder, not otherwise specified
0.000 0.995 0.005
Y57.9 Drug or medicament, unspecified
0.000 0.995 0.005
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.000 0.995 0.004
F93 Emotional disorders with onset specific to childhood
0.000 0.995 0.004
F92 Mixed disorders of conduct and emotions
0.000 0.995 0.004
F91 Conduct disorders
0.000 0.995 0.004
D84.1 Defects in the complement system
0.004 0.995 0.000
R68.2 Dry mouth, unspecified
0.004 0.995 0.000
F84.5 Asperger's syndrome
0.000 0.995 0.004
F60-F69 Disorders of adult personality and behaviour
0.000 0.995 0.004
F39 Unspecified mood [affective] disorder
0.000 0.996 0.004
F95 Tic disorders
0.000 0.996 0.004
D89.0 Polyclonal hypergammaglobulinaemia
0.004 0.996 0.000
F90 Hyperkinetic disorders
0.000 0.996 0.004
K72.9 Hepatic failure, unspecified
0.004 0.996 0.000
Q66.8 Other congenital deformities of feet
0.004 0.996 0.000
F81.8 Other developmental disorders of scholastic skills
0.000 0.996 0.004
F81.3 Mixed disorder of scholastic skills
0.000 0.996 0.004
F81.2 Specific disorder of arithmetical skills
0.000 0.996 0.004
F81.1 Specific spelling disorder
0.000 0.996 0.004
F81.0 Specific reading disorder
0.000 0.996 0.004
J81 Pulmonary oedema
0.004 0.996 0.000
F28 Other nonorganic psychotic disorders
0.000 0.996 0.004
F24 Induced delusional disorder
0.000 0.996 0.004
F21 Schizotypal disorder
0.000 0.996 0.004
R61.1 Generalised hyperhidrosis
0.004 0.996 0.000
F30-F39 Mood [affective] disorders
0.000 0.996 0.004
R68.1 Nonspecific symptoms peculiar to infancy
0.004 0.996 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.004 0.996 0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.001 0.996 0.004
O62.2 Other uterine inertia
0.000 0.996 0.004
D84.9 Immunodeficiency, unspecified
0.004 0.996 0.000
F70.9 Mild mental retardation (Without mention of impairment of behaviour)
0.000 0.996 0.004
F70.8 Mild mental retardation (Other impairments of behaviour)
0.000 0.996 0.004
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.996 0.004
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.996 0.004
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)
0.000 0.996 0.004
F71.8 Moderate mental retardation (Other impairments of behaviour)
0.000 0.996 0.004
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.996 0.004
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.996 0.004
F72.9 Severe mental retardation (Without mention of impairment of behaviour)
0.000 0.996 0.004
F72.8 Severe mental retardation (Other impairments of behaviour)
0.000 0.996 0.004
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.996 0.004
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.996 0.004
F73.9 Profound mental retardation (Without mention of impairment of behaviour)
0.000 0.996 0.004
F73.8 Profound mental retardation (Other impairments of behaviour)
0.000 0.996 0.004
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.996 0.004
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.996 0.004
F78.9 Other mental retardation (Without mention of impairment of behaviour)
0.000 0.996 0.004
F78.8 Other mental retardation (Other impairments of behaviour)
0.000 0.996 0.004
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.996 0.004
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.996 0.004
F23 Acute and transient psychotic disorders
0.000 0.996 0.004
E28.2 Polycystic ovarian syndrome
0.000 0.996 0.004
G12.2 Motor neuron disease
0.000 0.996 0.004
Q66 Congenital deformities of feet
0.004 0.996 0.000
F34 Persistent mood [affective] disorders
0.000 0.996 0.004
I49 Other cardiac arrhythmias
0.004 0.996 0.000
F79.8 Unspecified mental retardation (Other impairments of behaviour)
0.000 0.996 0.004
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.996 0.004
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.996 0.004
R68.3 Clubbing of fingers
0.004 0.996 0.000
F34.1 Dysthymia
0.000 0.996 0.004
F69 Unspecified disorder of adult personality and behaviour
0.000 0.996 0.004
G12 Spinal muscular atrophy and related syndromes
0.000 0.996 0.004
Chapter VI Diseases of the nervous system
0.000 0.996 0.004
O61.0 Failed medical induction of labour
0.004 0.996 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.996 0.004
Q67.6 Pectus excavatum
0.004 0.996 0.000
F11.2 Dependence syndrome
0.000 0.996 0.004
J84.1 Other interstitial pulmonary diseases with fibrosis
0.004 0.996 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.004 0.996 0.000
F25 Schizoaffective disorders
0.000 0.996 0.004
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.996 0.004
F91.9 Conduct disorder, unspecified
0.000 0.996 0.003
F91.8 Other conduct disorders
0.000 0.996 0.003
F91.3 Oppositional defiant disorder
0.000 0.996 0.003
F91.2 Socialised conduct disorder
0.000 0.996 0.003
F91.1 Unsocialised conduct disorder
0.000 0.996 0.003
F91.0 Conduct disorder confined to the family context
0.000 0.996 0.003
F92.9 Mixed disorder of conduct and emotions, unspecified
0.000 0.996 0.003
F92.8 Other mixed disorders of conduct and emotions
0.000 0.996 0.003
F92.0 Depressive conduct disorder
0.000 0.996 0.003
F93.9 Childhood emotional disorder, unspecified
0.000 0.996 0.003
F93.8 Other childhood emotional disorders
0.000 0.996 0.003
F93.3 Sibling rivalry disorder
0.000 0.996 0.003
F93.2 Social anxiety disorder of childhood
0.000 0.996 0.003
F93.1 Phobic anxiety disorder of childhood
0.000 0.996 0.003
F93.0 Separation anxiety disorder of childhood
0.000 0.996 0.003
F94.9 Childhood disorder of social functioning, unspecified
0.000 0.996 0.003
F94.8 Other childhood disorders of social functioning
0.000 0.996 0.003
F94.2 Disinhibited attachment disorder of childhood
0.000 0.996 0.003
F94.1 Reactive attachment disorder of childhood
0.000 0.996 0.003
F94.0 Elective mutism
0.000 0.996 0.003
Q68 Other congenital musculoskeletal deformities
0.003 0.996 0.000
D04.3 Skin of other and unspecified parts of face
0.004 0.996 0.000
F11 Mental and behavioural disorders due to use of opioids
0.000 0.996 0.003
Q78 Other osteochondrodysplasias
0.003 0.996 0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.000 0.996 0.003
Q66.6 Other congenital valgus deformities of feet
0.003 0.996 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.000 0.996 0.003
F65 Disorders of sexual preference
0.000 0.996 0.003
F63 Habit and impulse disorders
0.000 0.996 0.003
F62 Enduring personality changes, not attributable to brain damage and disease
0.000 0.996 0.003
S00.9 Superficial injury of head, part unspecified
0.003 0.997 0.000
F95.9 Tic disorder, unspecified
0.000 0.997 0.003
F95.8 Other tic disorders
0.000 0.997 0.003
F95.1 Chronic motor or vocal tic disorder
0.000 0.997 0.003
F95.0 Transient tic disorder
0.000 0.997 0.003
M79.69 Pain in limb (Site unspecified)
0.003 0.997 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.003 0.997 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.003 0.997 0.000
F90.9 Hyperkinetic disorder, unspecified
0.000 0.997 0.003
F90.8 Other hyperkinetic disorders
0.000 0.997 0.003
F90.1 Hyperkinetic conduct disorder
0.000 0.997 0.003
F68 Other disorders of adult personality and behaviour
0.000 0.997 0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.003 0.997 0.000
F61 Mixed and other personality disorders
0.000 0.997 0.003
F23.9 Acute and transient psychotic disorder, unspecified
0.000 0.997 0.003
O62.0 Primary inadequate contractions
0.000 0.997 0.003
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]
0.000 0.997 0.003
Q74 Other congenital malformations of limb(s)
0.003 0.997 0.000
I49.1 Atrial premature depolarisation
0.003 0.997 0.000
G72.9 Myopathy, unspecified
0.000 0.997 0.003
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.003 0.997 0.000
G70-G73 Diseases of myoneural junction and muscle
0.000 0.997 0.003
Q65 Congenital deformities of hip
0.003 0.997 0.000
F38 Other mood [affective] disorders
0.000 0.997 0.003
G11.9 Hereditary ataxia, unspecified
0.000 0.997 0.003
Q68.8 Other specified congenital musculoskeletal deformities
0.003 0.997 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.997 0.003
G11 Hereditary ataxia
0.000 0.997 0.003
F33 Recurrent depressive disorder
0.000 0.997 0.003
K90 Intestinal malabsorption
0.003 0.997 0.000
Q75 Other congenital malformations of skull and face bones
0.003 0.997 0.000
Q73 Reduction defects of unspecified limb
0.003 0.997 0.000
Q72 Reduction defects of lower limb
0.003 0.997 0.000
Q71 Reduction defects of upper limb
0.003 0.997 0.000
Q70 Syndactyly
0.003 0.997 0.000
Q69 Polydactyly
0.003 0.997 0.000
F90.0 Disturbance of activity and attention
0.000 0.997 0.003
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.001 0.997 0.003
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.001 0.997 0.003
F98.6 Cluttering
0.001 0.997 0.003
F98.4 Stereotyped movement disorders
0.001 0.997 0.003
F98.3 Pica of infancy and childhood
0.001 0.997 0.003
F98.2 Feeding disorder of infancy and childhood
0.001 0.997 0.003
F98.1 Nonorganic encopresis
0.001 0.997 0.003
F98.0 Nonorganic enuresis
0.001 0.997 0.003
N64.4 Mastodynia
0.003 0.997 0.000
G72 Other myopathies
0.000 0.997 0.003
O62 Abnormalities of forces of labour
0.000 0.997 0.003
F81.9 Developmental disorder of scholastic skills, unspecified
0.000 0.997 0.003
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.003 0.997 0.000
Q76 Congenital malformations of spine and bony thorax
0.003 0.997 0.000
F11.1 Harmful use
0.000 0.997 0.003
Q66.0 Talipes equinovarus
0.003 0.997 0.000
F23.8 Other acute and transient psychotic disorders
0.000 0.997 0.003
F23.2 Acute schizophrenia-like psychotic disorder
0.000 0.997 0.003
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.000 0.997 0.003
Q66.5 Congenital pes planus
0.003 0.997 0.000
Q66.4 Talipes calcaneovalgus
0.003 0.997 0.000
Q66.1 Talipes calcaneovarus
0.003 0.997 0.000
O62.3 Precipitate labour
0.000 0.997 0.003
Q78.0 Osteogenesis imperfecta
0.003 0.997 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.997 0.003
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.997 0.003
F34.8 Other persistent mood [affective] disorders
0.000 0.997 0.003
F34.0 Cyclothymia
0.000 0.997 0.003
I49.8 Other specified cardiac arrhythmias
0.003 0.997 0.000
I49.2 Junctional premature depolarisation
0.003 0.997 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.003 0.997 0.000
F22 Persistent delusional disorders
0.000 0.997 0.003
N85.4 Malposition of uterus
0.003 0.997 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.003 0.997 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.003 0.997 0.000
G12.9 Spinal muscular atrophy, unspecified
0.000 0.997 0.003
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.997 0.003
G12.1 Other inherited spinal muscular atrophy
0.000 0.997 0.003
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.997 0.003
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.997 0.003
G25.0 Essential tremor
0.000 0.997 0.003
Q78.2 Osteopetrosis
0.003 0.997 0.000
Z74.0 Reduced mobility
0.003 0.997 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.997 0.003
F64 Gender identity disorders
0.000 0.997 0.003
Q79.0 Congenital diaphragmatic hernia
0.003 0.997 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.997 0.003
G14 Postpolio syndrome
0.000 0.997 0.003
F12.1 Harmful use
0.000 0.997 0.003
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.997 0.003
F23.3 Other acute predominantly delusional psychotic disorders
0.000 0.997 0.003
Q66.7 Pes cavus
0.003 0.997 0.000
Q67.8 Other congenital deformities of chest
0.003 0.997 0.000
Q67.7 Pectus carinatum
0.003 0.997 0.000
Q67.3 Plagiocephaly
0.003 0.997 0.000
Q67.2 Dolichocephaly
0.003 0.997 0.000
Q67.1 Compression facies
0.003 0.997 0.000
Q67.0 Facial asymmetry
0.003 0.997 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.003 0.997 0.000
F25.2 Schizoaffective disorder, mixed type
0.000 0.997 0.003
F25.8 Other schizoaffective disorders
0.000 0.997 0.003
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.997 0.003
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.997 0.003
Z94.0 Kidney transplant status
0.003 0.997 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.997 0.003
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.997 0.003
F11.9 Unspecified mental and behavioural disorder
0.000 0.997 0.003
F11.8 Other mental and behavioural disorders
0.000 0.997 0.003
F11.7 Residual and late-onset psychotic disorder
0.000 0.997 0.003
F11.6 Amnesic syndrome
0.000 0.997 0.003
F11.5 Psychotic disorder
0.000 0.997 0.003
F11.4 Withdrawal state with delirium
0.000 0.997 0.003
F11.0 Acute intoxication
0.000 0.997 0.003
G72.0 Drug-induced myopathy
0.000 0.997 0.003
Q68.5 Congenital bowing of long bones of leg, unspecified
0.003 0.997 0.000
Q68.4 Congenital bowing of tibia and fibula
0.003 0.997 0.000
Q68.3 Congenital bowing of femur
0.003 0.997 0.000
Q68.2 Congenital deformity of knee
0.003 0.997 0.000
Q68.1 Congenital deformity of hand
0.003 0.997 0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle
0.003 0.997 0.000
D04.4 Skin of scalp and neck
0.003 0.997 0.000
Q78.9 Osteochondrodysplasia, unspecified
0.003 0.997 0.000
Q78.8 Other specified osteochondrodysplasias
0.003 0.997 0.000
Q78.6 Multiple congenital exostoses
0.003 0.997 0.000
Q78.5 Metaphyseal dysplasia
0.003 0.997 0.000
Q78.4 Enchondromatosis
0.003 0.997 0.000
Q78.3 Progressive diaphyseal dysplasia
0.003 0.997 0.000
Q78.1 Polyostotic fibrous dysplasia
0.003 0.997 0.000
R25.1 Tremor, unspecified
0.003 0.997 0.000
G71 Primary disorders of muscles
0.000 0.997 0.003
F62.8 Other enduring personality changes
0.000 0.997 0.003
F62.1 Enduring personality change after psychiatric illness
0.000 0.997 0.003
F62.0 Enduring personality change after catastrophic experience
0.000 0.997 0.003
F63.9 Habit and impulse disorder, unspecified
0.000 0.997 0.003
F63.8 Other habit and impulse disorders
0.000 0.997 0.003
F63.3 Trichotillomania
0.000 0.997 0.003
F63.2 Pathological stealing [kleptomania]
0.000 0.997 0.003
F63.1 Pathological fire-setting [pyromania]
0.000 0.997 0.003
F63.0 Pathological gambling
0.000 0.997 0.003
F65.9 Disorder of sexual preference, unspecified
0.000 0.997 0.003
F65.8 Other disorders of sexual preference
0.000 0.997 0.003
F65.6 Multiple disorders of sexual preference
0.000 0.997 0.003
F65.5 Sadomasochism
0.000 0.997 0.003
F65.4 Paedophilia
0.000 0.997 0.003
F65.3 Voyeurism
0.000 0.997 0.003
F65.2 Exhibitionism
0.000 0.997 0.003
F65.1 Fetishistic transvestism
0.000 0.997 0.003
F65.0 Fetishism
0.000 0.997 0.003
F66.9 Psychosexual development disorder, unspecified
0.000 0.997 0.003
F66.8 Other psychosexual development disorders
0.000 0.997 0.003
F66.2 Sexual relationship disorder
0.000 0.997 0.003
F66.1 Egodystonic sexual orientation
0.000 0.997 0.003
F66.0 Sexual maturation disorder
0.000 0.997 0.003
Q66.3 Other congenital varus deformities of feet
0.003 0.997 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.000 0.997 0.003
F62.9 Enduring personality change, unspecified
0.000 0.997 0.003
Q66.9 Congenital deformity of feet, unspecified
0.003 0.997 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.003 0.997 0.000
Q66.2 Metatarsus varus
0.003 0.997 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.000 0.997 0.003
I49.4 Other and unspecified premature depolarisation
0.003 0.997 0.000
S22.30 Fracture of rib (closed)
0.000 0.997 0.003
D04.5 Skin of trunk
0.003 0.997 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.003 0.997 0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.003 0.997 0.000
Q79.5 Other congenital malformations of abdominal wall
0.003 0.997 0.000
Q79.4 Prune belly syndrome
0.003 0.997 0.000
Q79.3 Gastroschisis
0.003 0.997 0.000
Q79.2 Exomphalos
0.003 0.997 0.000
Q79.1 Other congenital malformations of diaphragm
0.003 0.997 0.000
J84 Other interstitial pulmonary diseases
0.003 0.997 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.997 0.003
F25.0 Schizoaffective disorder, manic type
0.000 0.997 0.003
F68.8 Other specified disorders of adult personality and behaviour
0.000 0.997 0.002
F68.0 Elaboration of physical symptoms for psychological reasons
0.000 0.997 0.002
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.997 0.003
G82 Paraplegia and tetraplegia
0.000 0.997 0.003
F98.5 Stuttering [stammering]
0.001 0.997 0.002
G62.0 Drug-induced polyneuropathy
0.000 0.997 0.003
Q65.8 Other congenital deformities of hip
0.003 0.997 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.003 0.997 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.003 0.997 0.000
Q74.3 Arthrogryposis multiplex congenita
0.003 0.997 0.000
D04 Carcinoma in situ of skin
0.003 0.997 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.997 0.003
G72.1 Alcoholic myopathy
0.000 0.997 0.003
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.997 0.002
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.997 0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.003 0.997 0.000
F25.1 Schizoaffective disorder, depressive type
0.000 0.997 0.002
K72.0 Acute and subacute hepatic failure
0.003 0.997 0.000
Q65.9 Congenital deformity of hip, unspecified
0.002 0.997 0.000
Q65.6 Unstable hip
0.002 0.997 0.000
Q65.5 Congenital subluxation of hip, unspecified
0.002 0.997 0.000
Q65.4 Congenital subluxation of hip, bilateral
0.002 0.997 0.000
Q65.3 Congenital subluxation of hip, unilateral
0.002 0.997 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.002 0.997 0.000
Q65.1 Congenital dislocation of hip, bilateral
0.002 0.997 0.000
Q65.0 Congenital dislocation of hip, unilateral
0.002 0.997 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.997 0.003
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.997 0.003
F38.8 Other specified mood [affective] disorders
0.000 0.997 0.002
F38.1 Other recurrent mood [affective] disorders
0.000 0.997 0.002
F38.0 Other single mood [affective] disorders
0.000 0.997 0.002
G11.8 Other hereditary ataxias
0.000 0.997 0.002
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.997 0.002
G11.2 Late-onset cerebellar ataxia
0.000 0.997 0.002
G11.0 Congenital nonprogressive ataxia
0.000 0.997 0.002
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.003 0.997 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.002 0.997 0.000
Q76.5 Cervical rib
0.002 0.997 0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.000 0.997 0.002
K90.3 Pancreatic steatorrhoea
0.002 0.997 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.002 0.997 0.000
K90.1 Tropical sprue
0.002 0.997 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.000 0.997 0.003
Q74.1 Congenital malformation of knee
0.002 0.997 0.000
O62.8 Other abnormalities of forces of labour
0.000 0.997 0.002
Q22.1 Congenital pulmonary valve stenosis
0.003 0.997 0.000
Q69.9 Polydactyly, unspecified
0.002 0.997 0.000
Q69.2 Accessory toe(s)
0.002 0.997 0.000
Q69.1 Accessory thumb(s)
0.002 0.997 0.000
Q69.0 Accessory finger(s)
0.002 0.997 0.000
Q70.9 Syndactyly, unspecified
0.002 0.997 0.000
Q70.4 Polysyndactyly
0.002 0.997 0.000
Q70.3 Webbed toes
0.002 0.997 0.000
Q70.2 Fused toes
0.002 0.997 0.000
Q70.1 Webbed fingers
0.002 0.997 0.000
Q70.0 Fused fingers
0.002 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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