TreeWAS – Variant ID: rs77090108

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter II Neoplasms	0.998	0.002
Chapter X Diseases of the respiratory system	0.998	0.002
D37-D48 Neoplasms of uncertain or unknown behaviour	0.996	0.004
M50-M54 Other dorsopathies	0.995	0.005
J95-J99 Other diseases of the respiratory system	0.995	0.005
J98 Other respiratory disorders	0.993	0.007
M70-M79 Other soft tissue disorders	0.991	0.009
C15-C26 Malignant neoplasms of digestive organs	0.991	0.009
M79 Other soft tissue disorders, not elsewhere classified	0.990	0.010
M20-M25 Other joint disorders	0.988	0.012
M51 Other intervertebral disk disorders	0.986	0.014
Chapter XX External causes of morbidity and mortality	0.985	0.015
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.985	0.015
Chapter I Certain infectious and parasitic diseases	0.982	0.018
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.980	0.020
Chapter XIV Diseases of the genitourinary system	0.979	0.021
M51.2 Other specified intervertebral disk displacement	0.978	0.022
J98.1 Pulmonary collapse	0.978	0.022
C18 Malignant neoplasm of colon	0.978	0.022
N32 Other disorders of bladder	0.977	0.023
M79.0 Rheumatism, unspecified	0.976	0.024
N32.8 Other specified disorders of bladder	0.975	0.025
N30-N39 Other diseases of urinary system	0.973	0.027
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.968	0.032
D45 Polycythaemia vera	0.968	0.032
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.965	0.035
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.962	0.038
Chapter XV Pregnancy, childbirth and the puerperium	0.955	0.045
D47.3 Essential (haemorrhagic) thrombocythaemia	0.955	0.045
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.954	0.046
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.951	0.049
M79.09 Rheumatism, unspecified (Site unspecified)	0.948	0.052
A30-A49 Other bacterial diseases	0.943	0.057
N32.9 Bladder disorder, unspecified	0.941	0.059
B35-B49 Mycoses	0.941	0.059
O20-O29 Other maternal disorders predominantly related to pregnancy	0.940	0.060
S00-S09 Injuries to the head	0.939	0.061
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.937	0.063
S00 Superficial injury of head	0.936	0.064
Chapter IV Endocrine, nutritional and metabolic diseases	0.933	0.067
C15 Malignant neoplasm of oesophagus	0.925	0.075
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.925	0.075
S00.8 Superficial injury of other parts of head	0.924	0.076
M22 Disorders of patella	0.916	0.084
J98.4 Other disorders of lung	0.915	0.085
A41 Other septicaemia	0.915	0.085
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.914	0.086
N32.3 Diverticulum of bladder	0.912	0.088
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.911	0.089
E70-E90 Metabolic disorders	0.910	0.090
J30-J39 Other diseases of upper respiratory tract	0.906	0.094
M25 Other joint disorders, not elsewhere classified	0.903	0.097
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.902	0.098
B37 Candidiasis	0.901	0.099
Y84.2 Radiological procedure and radiotherapy	0.899	0.101
M54 Dorsalgia	0.896	0.104
M79.6 Pain in limb	0.893	0.107
D68 Other coagulation defects	0.892	0.108
J33 Nasal polyp	0.888	0.112
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.886	0.114
C90 Multiple myeloma and malignant plasma cell neoplasms	0.884	0.116
O26 Maternal care for other conditions predominantly related to pregnancy	0.883	0.117
M79.00 Rheumatism, unspecified (Multiple sites)	0.881	0.119
M54.5 Low back pain	0.880	0.120
E83 Disorders of mineral metabolism	0.877	0.123
S90-S99 Injuries to the ankle and foot	0.873	0.126
Y83.2 Surgical operation with anastomosis, bypass or graft	0.871	0.129
N17-N19 Renal failure	0.869	0.131
O94-O99 Other obstetric conditions, not elsewhere classified	0.868	0.132
M79.1 Myalgia	0.864	0.136
M54.59 Low back pain (Site unspecified)	0.864	0.136
M05-M14 Inflammatory polyarthropathies	0.861	0.139
M65-M68 Disorders of synovium and tendon	0.861	0.139
E40-E46 Malnutrition	0.861	0.139
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.858	0.142
C18.0 Caecum	0.855	0.145
M60-M63 Disorders of muscles	0.854	0.146
J32 Chronic sinusitis	0.854	0.146
T15-T19 Effects of foreign body entering through natural orifice	0.854	0.146
M21 Other acquired deformities of limbs	0.852	0.148
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.847	0.153
J33.8 Other polyp of sinus	0.844	0.156
C18.9 Colon, unspecified	0.842	0.158
M70 Soft tissue disorders related to use, overuse and pressure	0.841	0.159
T80 Complications following infusion, transfusion and therapeutic injection	0.839	0.161
C15.9 Oesophagus, unspecified	0.839	0.161
M79.8 Other specified soft tissue disorders	0.837	0.163
O26.9 Pregnancy-related condition, unspecified	0.837	0.163
J09-J18 Influenza and pneumonia	0.836	0.164
C18.5 Splenic flexure	0.836	0.164
M79.65 Pain in limb (Pelvic region and thigh)	0.833	0.167
E86 Volume depletion	0.833	0.167
S00.0 Superficial injury of scalp	0.829	0.171
J98.0 Diseases of bronchus, not elsewhere classified	0.828	0.172
E83.4 Disorders of magnesium metabolism	0.828	0.172
D68.2 Hereditary deficiency of other clotting factors	0.827	0.173
O24 Diabetes mellitus in pregnancy	0.824	0.176
C16 Malignant neoplasm of stomach	0.822	0.178
B37.9 Candidiasis, unspecified	0.818	0.182
J32.9 Chronic sinusitis, unspecified	0.816	0.184
M54.56 Low back pain (Lumbar region)	0.816	0.184
M22.4 Chondromalacia patellae	0.815	0.185
C90.0 Multiple myeloma	0.814	0.186
D47.1 Chronic myeloproliferative disease	0.814	0.186
B37.0 Candidal stomatitis	0.813	0.187
N19 Unspecified renal failure	0.812	0.188
M25.7 Osteophyte	0.809	0.191
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.809	0.191
E46 Unspecified protein-energy malnutrition	0.809	0.191
C18.2 Ascending colon	0.807	0.193
C18.7 Sigmoid colon	0.807	0.193
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.806	0.194
J33.0 Polyp of nasal cavity	0.804	0.196
J37 Chronic laryngitis and laryngotracheitis	0.802	0.198
Chapter XXII Codes for special purposes	0.801	0.199
C18.6 Descending colon	0.800	0.200
E20-E35 Disorders of other endocrine glands	0.799	0.201
J99 Respiratory disorders in diseases classified elsewhere	0.798	0.202
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.798	0.202
M06 Other rheumatoid arthritis	0.797	0.203
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.797	0.203
M51.9 Intervertebral disk disorder, unspecified	0.796	0.204
Q80-Q89 Other congenital malformations	0.796	0.204
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.795	0.204
M40-M43 Deforming dorsopathies	0.795	0.205
M30 Polyarteritis nodosa and related conditions	0.794	0.206
O85-O92 Complications predominantly related to the puerperium	0.792	0.208
A40 Streptococcal septicaemia	0.792	0.208
Y83.8 Other surgical procedures	0.791	0.209
T20-T25 Burns and corrosions of external body surface, specified by site	0.790	0.210
X00-X09 Exposure to smoke, fire and flames	0.789	0.211
N25-N29 Other disorders of kidney and ureter	0.786	0.214
A41.0 Septicaemia due to Staphylococcus aureus	0.786	0.214
N00-N08 Glomerular diseases	0.785	0.215
N70-N77 Inflammatory diseases of female pelvic organs	0.785	0.215
C83 Diffuse non-Hodgkin's lymphoma	0.782	0.217
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.782	0.218
D00-D09 In situ neoplasms	0.782	0.218
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.781	0.219
M50 Cervical disk disorders	0.781	0.219
Q20-Q28 Congenital malformations of the circulatory system	0.779	0.221
E88 Other metabolic disorders	0.779	0.221
E83.5 Disorders of calcium metabolism	0.779	0.221
O21 Excessive vomiting in pregnancy	0.779	0.221
C15.4 Middle third of oesophagus	0.775	0.225
A41.5 Septicaemia due to other Gram-negative organisms	0.775	0.225
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.774	0.226
J00-J06 Acute upper respiratory infections	0.773	0.227
D68.9 Coagulation defect, unspecified	0.770	0.230
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.770	0.230
D68.6 Other Thrombophilia	0.767	0.233
D47.4 Osteomyelofibrosis	0.765	0.235
A41.9 Septicaemia, unspecified	0.765	0.235
T87 Complications peculiar to reattachment and amputation	0.765	0.235
O23 Infections of genito-urinary tract in pregnancy	0.764	0.236
V40-V49 Car occupant injured in transport accident	0.763	0.237
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.762	0.238
J98.6 Disorders of diaphragm	0.762	0.238
M79.89 Other specified soft tissue disorders (Site unspecified)	0.761	0.239
M35 Other systemic involvement of connective tissue	0.761	0.239
M91-M94 Chondropathies	0.761	0.239
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.759	0.241
J98.8 Other specified respiratory disorders	0.759	0.241
Y95 Nosocomial condition	0.757	0.243
S00.2 Other superficial injuries of eyelid and periocular area	0.756	0.244
N17 Acute renal failure	0.755	0.245
M23 Internal derangement of knee	0.753	0.247
M06.9 Rheumatoid arthritis, unspecified	0.753	0.247
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.752	0.247
V10-V19 Pedal cyclist injured in transport accident	0.752	0.247
B20-B24 Human immunodeficiency virus [HIV] disease	0.751	0.249
M79.62 Pain in limb (Upper arm)	0.749	0.251
M45-M49 Spondylopathies	0.747	0.253
B95-B98 Bacterial, viral and other infectious agents	0.746	0.254
C91 Lymphoid leukaemia	0.746	0.254
W00-W19 Falls	0.746	0.254
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.745	0.255
Y84.1 Kidney dialysis	0.745	0.255
X50-X57 Overexertion, travel and privation	0.744	0.256
M25.71 Osteophyte (Shoulder region)	0.743	0.257
M65 Synovitis and tenosynovitis	0.742	0.258
J90-J94 Other diseases of pleura	0.741	0.259
M79.9 Soft tissue disorder, unspecified	0.741	0.259
S90 Superficial injury of ankle and foot	0.740	0.260
M22.8 Other disorders of patella	0.740	0.260
T00-T07 Injuries involving multiple body regions	0.740	0.260
Y84.0 Cardiac catheterisation	0.740	0.260
B44 Aspergillosis	0.739	0.261
T82.4 Mechanical complication of vascular dialysis catheter	0.738	0.261
M79.16 Myalgia (Lower leg)	0.738	0.262
M25.9 Joint disorder, unspecified	0.738	0.262
M00-M03 Infectious arthropathies	0.738	0.262
S60-S69 Injuries to the wrist and hand	0.738	0.262
B49 Unspecified mycosis	0.737	0.263
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.737	0.263
Y00-Y09 Assault	0.737	0.263
A41.2 Septicaemia due to unspecified staphylococcus	0.737	0.263
M79.69 Pain in limb (Site unspecified)	0.736	0.264
A41.1 Septicaemia due to other specified staphylococcus	0.736	0.264
B50-B64 Protozoal diseases	0.736	0.264
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.734	0.266
Q60-Q64 Congenital malformations of the urinary system	0.733	0.267
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.732	0.268
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.732	0.268
T66-T78 Other and unspecified effects of external causes	0.731	0.269
C92 Myeloid leukaemia	0.731	0.269
N60-N64 Disorders of breast	0.730	0.270
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.729	0.271
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.729	0.271
D68.1 Hereditary factor XI deficiency	0.728	0.272
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.728	0.272
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.727	0.273
J37.0 Chronic laryngitis	0.727	0.273
Y83.9 Surgical procedure, unspecified	0.727	0.273
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.726	0.274
S70-S79 Injuries to the hip and thigh	0.725	0.275
M62 Other disorders of muscle	0.724	0.276
S00.5 Superficial injury of lip and oral cavity	0.723	0.276
C19 Malignant neoplasm of rectosigmoid junction	0.723	0.277
J15 Bacterial pneumonia, not elsewhere classified	0.723	0.277
M07 Psoriatic and enteropathic arthropathies	0.722	0.278
M25.3 Other instability of joint	0.721	0.279
M79.2 Neuralgia and neuritis, unspecified	0.721	0.279
C18.1 Appendix	0.721	0.279
M77 Other enthesopathies	0.719	0.281
S00.1 Contusion of eyelid and periocular area	0.719	0.281
N32.1 Vesicointestinal fistula	0.719	0.281
C88 Malignant immunoproliferative diseases	0.718	0.282
M24 Other specific joint derangements	0.718	0.282
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.718	0.282
Q50-Q56 Congenital malformations of genital organs	0.718	0.282
M50.1 Cervical disk disorder with radiculopathy	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
D47.2 Monoclonal gammopathy	0.717	0.283
N35 Urethral stricture	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
Q00-Q07 Congenital malformations of the nervous system	0.716	0.284
N10-N16 Renal tubulo-interstitial diseases	0.716	0.284
N76 Other inflammation of vagina and vulva	0.715	0.285
N99-N99 Other disorders of the genitourinary system	0.714	0.286
O24.4 Diabetes mellitus arising in pregnancy	0.714	0.286
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.714	0.286
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.714	0.286
M34 Systemic sclerosis	0.714	0.286
J96 Respiratory failure, not elsewhere classified	0.713	0.286
M79.7 Fibromyalgia	0.713	0.287
J98.5 Diseases of mediastinum, not elsewhere classified	0.712	0.288
J98.3 Compensatory emphysema	0.712	0.288
J98.2 Interstitial emphysema	0.712	0.288
M79.60 Pain in limb (Multiple sites)	0.712	0.288
J80-J84 Other respiratory diseases principally affecting the interstitium	0.711	0.289
D68.5 Primary Thrombophilia	0.711	0.289
M22.2 Patellofemoral disorders	0.711	0.289
M73 Soft tissue disorders in diseases classified elsewhere	0.711	0.289
C17 Malignant neoplasm of small intestine	0.711	0.289
C23 Malignant neoplasm of gallbladder	0.711	0.289
B99-B99 Other infectious diseases	0.710	0.290
M25.8 Other specified joint disorders	0.710	0.290
C79 Secondary malignant neoplasm of other sites	0.710	0.290
M79.4 Hypertrophy of (infrapatellar) fat pad	0.710	0.290
M79.3 Panniculitis, unspecified	0.710	0.290
D68.8 Other specified coagulation defects	0.709	0.291
O28 Abnormal findings on antenatal screening of mother	0.708	0.292
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.708	0.292
M33 Dermatopolymyositis	0.708	0.292
M32 Systemic lupus erythematosus	0.708	0.292
C84 Peripheral and cutaneous T-cell lymphomas	0.708	0.292
D55-D59 Haemolytic anaemias	0.708	0.292
J92 Pleural plaque	0.708	0.292
M51.3 Other specified intervertebral disk degeneration	0.707	0.293
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.707	0.293
M51.4 Schmorl's nodes	0.707	0.293
C20 Malignant neoplasm of rectum	0.707	0.293
Y35-Y36 Legal intervention and operations of war	0.706	0.294
Y10-Y34 Event of undetermined intent	0.706	0.294
X85-X99 Assault	0.706	0.294
X58-X59 Accidental exposure to other and unspecified factors	0.706	0.294
X30-X39 Exposure to forces of nature	0.706	0.294
X10-X19 Contact with heat and hot substances	0.706	0.294
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.706	0.294
W75-W84 Other accidental threats to breathing	0.706	0.294
W65-W74 Accidental drowning and submersion	0.706	0.294
V98-V99 Other and unspecified transport accidents	0.706	0.294
V95-V97 Air and space transport accidents	0.706	0.294
V90-V94 Water transport accidents	0.706	0.294
V70-V79 Bus occupant injured in transport accident	0.706	0.294
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.706	0.294
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.706	0.294
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.706	0.294
V01-V09 Pedestrian injured in transport accident	0.706	0.294
T33-T35 Frostbite	0.706	0.294
T26-T28 Burns and corrosions confined to eye and internal organs	0.706	0.294
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.706	0.294
M70.6 Trochanteric bursitis	0.706	0.294
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.705	0.295
C64-C68 Malignant neoplasms of urinary tract	0.705	0.295
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.705	0.295
D66 Hereditary factor VIII deficiency	0.704	0.295
M23.8 Other internal derangements of knee	0.704	0.296
S00.9 Superficial injury of head, part unspecified	0.704	0.296
M54.9 Dorsalgia, unspecified	0.704	0.296
B85-B89 Pediculosis, acariasis and other infestations	0.704	0.296
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.704	0.296
A75-A79 Rickettsioses	0.704	0.296
A70-A74 Other diseases caused by chlamydiae	0.704	0.296
A65-A69 Other spirochaetal diseases	0.704	0.296
A20-A28 Certain zoonotic bacterial diseases	0.704	0.296
A15-A19 Tuberculosis	0.704	0.296
B37.4 Candidiasis of other urogenital sites	0.704	0.296
S20-S29 Injuries to the thorax	0.703	0.297
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.703	0.297
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.703	0.297
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.703	0.297
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.703	0.297
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.703	0.297
M76 Enthesopathies of lower limb, excluding foot	0.702	0.298
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.702	0.298
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.702	0.298
C90.2 Plasmacytoma, extramedullary	0.701	0.299
C18.8 Overlapping lesion of colon	0.701	0.299
N32.4 Rupture of bladder, nontraumatic	0.701	0.299
N32.2 Vesical fistula, not elsewhere classified	0.701	0.299
M79.08 Rheumatism, unspecified (Other)	0.700	0.300
M79.07 Rheumatism, unspecified (Ankle and foot)	0.700	0.300
M79.06 Rheumatism, unspecified (Lower leg)	0.700	0.300
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.700	0.300
M79.04 Rheumatism, unspecified (Hand)	0.700	0.300
M79.03 Rheumatism, unspecified (Forearm)	0.700	0.300
M79.02 Rheumatism, unspecified (Upper arm)	0.700	0.300
M79.01 Rheumatism, unspecified (Shoulder region)	0.700	0.300
E74 Other disorders of carbohydrate metabolism	0.699	0.301
Chapter VIII Diseases of the ear and mastoid process	0.698	0.302
N37 Urethral disorders in diseases classified elsewhere	0.697	0.303
N33 Bladder disorders in diseases classified elsewhere	0.697	0.303
M65.9 Synovitis and tenosynovitis, unspecified	0.695	0.305
Y83.0 Surgical operation with transplant of whole organ	0.695	0.305
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.693	0.307
W50-W64 Exposure to animate mechanical forces	0.692	0.308
W20-W49 Exposure to inanimate mechanical forces	0.691	0.309
E22 Hyperfunction of pituitary gland	0.691	0.309
T18 Foreign body in alimentary tract	0.691	0.309
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.690	0.310
T82.0 Mechanical complication of heart valve prosthesis	0.690	0.310
C26 Malignant neoplasm of other and ill-defined digestive organs	0.690	0.310
M25.78 Osteophyte (Other)	0.690	0.310
S62 Fracture at wrist and hand level	0.689	0.311
T17 Foreign body in respiratory tract	0.687	0.312
M86-M90 Other osteopathies	0.687	0.313
N34 Urethritis and urethral syndrome	0.687	0.313
M21.1 Varus deformity, not elsewhere classified	0.686	0.314
T82.3 Mechanical complication of other vascular grafts	0.685	0.315
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.685	0.315
E85 Amyloidosis	0.685	0.315
S00.7 Multiple superficial injuries of head	0.684	0.316
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.684	0.316
C95 Leukaemia of unspecified cell type	0.684	0.316
C94 Other leukaemias of specified cell type	0.684	0.316
C93 Monocytic leukaemia	0.684	0.316
C86 Other specified types of T/NK-cell lymphoma	0.684	0.316
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.682	0.318
Q35-Q37 Cleft lip and cleft palate	0.682	0.318
Q30-Q34 Congenital malformations of the respiratory system	0.682	0.318
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.680	0.320
V80-V89 Other land transport accidents	0.680	0.320
M25.6 Stiffness of joint, not elsewhere classified	0.680	0.320
J32.1 Chronic frontal sinusitis	0.679	0.321
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.679	0.321
J92.9 Pleural plaque without asbestos	0.679	0.321
S05 Injury of eye and orbit	0.679	0.321
Y40 Systemic antibiotics	0.679	0.321
J95 Postprocedural respiratory disorders, not elsewhere classified	0.679	0.321
X40-X49 Accidental poisoning by and exposure to noxious substances	0.678	0.322
B90-B94 Sequelae of infectious and parasitic diseases	0.678	0.322
C15.5 Lower third of oesophagus	0.676	0.324
A48 Other bacterial diseases, not elsewhere classified	0.676	0.324
A44 Bartonellosis	0.676	0.324
A43 Nocardiosis	0.676	0.324
A42 Actinomycosis	0.676	0.324
A39 Meningococcal infection	0.676	0.324
A37 Whooping cough	0.676	0.324
A36 Diphtheria	0.676	0.324
A32 Listeriosis	0.676	0.324
A31 Infection due to other mycobacteria	0.676	0.324
A30 Leprosy [Hansen's disease]	0.676	0.324
A38 Scarlet fever	0.676	0.324
A35 Other tetanus	0.676	0.324
A34 Obstetrical tetanus	0.676	0.324
A33 Tetanus neonatorum	0.676	0.324
D37.7 Other digestive organs	0.676	0.324
T82.1 Mechanical complication of cardiac electronic device	0.675	0.324
T88 Other complications of surgical and medical care, not elsewhere classified	0.675	0.325
D03 Melanoma in situ	0.675	0.325
B48 Other mycoses, not elsewhere classified	0.675	0.325
B47 Mycetoma	0.675	0.325
B46 Zygomycosis	0.675	0.325
B45 Cryptococcosis	0.675	0.325
B43 Chromomycosis and phaeomycotic abscess	0.675	0.325
B42 Sporotrichosis	0.675	0.325
B41 Paracoccidioidomycosis	0.675	0.325
B40 Blastomycosis	0.675	0.325
B39 Histoplasmosis	0.675	0.325
B38 Coccidioidomycosis	0.675	0.325
B36 Other superficial mycoses	0.675	0.325
O29 Complications of anaesthesia during pregnancy	0.674	0.326
O22 Venous complications in pregnancy	0.674	0.326
O25 Malnutrition in pregnancy	0.674	0.326
J18 Pneumonia, organism unspecified	0.674	0.326
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.674	0.326
S10-S19 Injuries to the neck	0.673	0.327
M41 Scoliosis	0.673	0.327
S08 Traumatic amputation of part of head	0.673	0.327
S07 Crushing injury of head	0.673	0.327
S04 Injury of cranial nerves	0.673	0.327
S03 Dislocation, sprain and strain of joints and ligaments of head	0.673	0.327
D69 Purpura and other haemorrhagic conditions	0.672	0.328
M79.10 Myalgia (Multiple sites)	0.672	0.328
M80-M85 Disorders of bone density and structure	0.671	0.328
S00.4 Superficial injury of ear	0.671	0.329
J33.9 Nasal polyp, unspecified	0.671	0.329
Q38-Q45 Other congenital malformations of the digestive system	0.670	0.330
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.670	0.330
B65-B83 Helminthiases	0.670	0.330
C16.9 Stomach, unspecified	0.670	0.330
M67 Other disorders of synovium and tendon	0.669	0.331
M31 Other necrotising vasculopathies	0.668	0.332
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.668	0.332
A80-A89 Viral infections of the central nervous system	0.668	0.332
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.667	0.332
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.667	0.333
X60-X84 Intentional self-harm	0.667	0.333
T85 Complications of other internal prosthetic devices, implants and grafts	0.667	0.333
M22.3 Other derangements of patella	0.666	0.334
C18.4 Transverse colon	0.665	0.335
M70.4 Prepatellar bursitis	0.665	0.335
M96.0 Pseudarthrosis after fusion or arthrodesis	0.664	0.336
C15.8 Overlapping lesion of oesophagus	0.663	0.336
C15.3 Upper third of oesophagus	0.663	0.336
C15.2 Abdominal part of oesophagus	0.663	0.336
C15.1 Thoracic part of oesophagus	0.663	0.336
C15.0 Cervical part of oesophagus	0.663	0.336
Y84.9 Medical procedure, unspecified	0.663	0.337
Y84.7 Blood-sampling	0.663	0.337
Y84.5 Insertion of gastric or duodenal sound	0.663	0.337
Y84.4 Aspiration of fluid	0.663	0.337
Y84.3 Shock therapy	0.663	0.337
M79.63 Pain in limb (Forearm)	0.663	0.337
J98.9 Respiratory disorder, unspecified	0.663	0.337
N05 Unspecified nephritic syndrome	0.661	0.339
X20-X29 Contact with venomous animals and plants	0.660	0.339
N28 Other disorders of kidney and ureter, not elsewhere classified	0.660	0.340
T79-T79 Certain early complications of trauma	0.660	0.340
M21.0 Valgus deformity, not elsewhere classified	0.660	0.340
O26.8 Other specified pregnancy-related conditions	0.659	0.341
A40.9 Streptococcal septicaemia, unspecified	0.659	0.341
M60 Myositis	0.658	0.341
E29 Testicular dysfunction	0.657	0.343
J99.8 Respiratory disorders in other diseases classified elsewhere	0.657	0.343
C83.3 Large cell (diffuse)	0.657	0.343
M22.1 Recurrent subluxation of patella	0.656	0.343
M22.9 Disorder of patella, unspecified	0.656	0.343
M22.0 Recurrent dislocation of patella	0.656	0.343
A41.4 Septicaemia due to anaerobes	0.656	0.344
A41.3 Septicaemia due to Haemophilus influenzae	0.656	0.344
C18.3 Hepatic flexure	0.654	0.345
N35.8 Other urethral stricture	0.654	0.346
C79.8 Secondary malignant neoplasm of other specified sites	0.653	0.347
E84 Cystic fibrosis	0.652	0.347
E79 Disorders of purine and pyrimidine metabolism	0.652	0.347
E77 Disorders of glycoprotein metabolism	0.652	0.347
E76 Disorders of glycosaminoglycan metabolism	0.652	0.347
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.652	0.347
E73 Lactose intolerance	0.652	0.347
E72 Other disorders of amino-acid metabolism	0.652	0.347
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.652	0.347
E70 Disorders of aromatic amino-acid metabolism	0.652	0.347
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.652	0.347
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.652	0.348
M79.80 Other specified soft tissue disorders (Multiple sites)	0.652	0.348
D40.1 Testis	0.652	0.348
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.651	0.349
C79.2 Secondary malignant neoplasm of skin	0.651	0.349
T16 Foreign body in ear	0.650	0.349
T23 Burn and corrosion of wrist and hand	0.650	0.350
J04 Acute laryngitis and tracheitis	0.649	0.351
C81 Hodgkin's disease	0.649	0.351
X09 Exposure to unspecified smoke, fire and flames	0.649	0.351
E83.3 Disorders of phosphorus metabolism	0.648	0.352
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.648	0.352
M25.4 Effusion of joint	0.648	0.352
M25.2 Flail joint	0.647	0.353
M25.1 Fistula of joint	0.647	0.353
D67 Hereditary factor IX deficiency	0.647	0.353
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.647	0.353
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.647	0.353
B37.7 Candidal septicaemia	0.646	0.354
B37.6 Candidal endocarditis	0.646	0.354
B37.5 Candidal meningitis	0.646	0.354
B37.2 Candidiasis of skin and nail	0.646	0.354

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations