TreeWAS – Variant ID: rs77095817

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
Chapter II Neoplasms	0.996	0.004
Chapter IV Endocrine, nutritional and metabolic diseases	0.992	0.008
C15-C26 Malignant neoplasms of digestive organs	0.990	0.010
H90-H95 Other disorders of ear	0.989	0.011
H91 Other hearing loss	0.986	0.014
H91.9 Hearing loss, unspecified	0.985	0.015
C18 Malignant neoplasm of colon	0.985	0.015
M70-M79 Other soft tissue disorders	0.984	0.016
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.981	0.019
Chapter XV Pregnancy, childbirth and the puerperium	0.981	0.019
Chapter V Mental and behavioural disorders	0.977	0.023
M79 Other soft tissue disorders, not elsewhere classified	0.975	0.025
S40-S49 Injuries to the shoulder and upper arm	0.970	0.030
H60-H62 Diseases of external ear	0.970	0.030
E20-E35 Disorders of other endocrine glands	0.966	0.034
S80-S89 Injuries to the knee and lower leg	0.963	0.037
T42.4 Benzodiazepines	0.961	0.039
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.955	0.045
D37-D48 Neoplasms of uncertain or unknown behaviour	0.954	0.046
D10-D36 Benign neoplasms	0.953	0.047
O00-O08 Pregnancy with abortive outcome	0.951	0.049
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.948	0.052
C18.7 Sigmoid colon	0.947	0.053
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.943	0.057
Chapter VI Diseases of the nervous system	0.942	0.058
M79.6 Pain in limb	0.939	0.061
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.939	0.061
S10-S19 Injuries to the neck	0.937	0.063
M20-M25 Other joint disorders	0.935	0.065
M65-M68 Disorders of synovium and tendon	0.934	0.066
H61 Other disorders of external ear	0.931	0.069
E10-E14 Diabetes mellitus	0.928	0.072
F10 Mental and behavioural disorders due to use of alcohol	0.922	0.078
E50-E64 Other nutritional deficiencies	0.920	0.080
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.920	0.080
O02 Other abnormal products of conception	0.915	0.085
C18.9 Colon, unspecified	0.912	0.088
M67 Other disorders of synovium and tendon	0.909	0.091
D12.5 Sigmoid colon	0.909	0.091
S81 Open wound of lower leg	0.906	0.094
Chapter XXII Codes for special purposes	0.899	0.101
E23 Hypofunction and other disorders of pituitary gland	0.898	0.102
T50.9 Other and unspecified drugs, medicaments and biological substances	0.895	0.105
O02.1 Missed abortion	0.893	0.107
M67.8 Other specified disorders of synovium and tendon	0.892	0.108
C19 Malignant neoplasm of rectosigmoid junction	0.891	0.109
Chapter XX External causes of morbidity and mortality	0.889	0.111
S20-S29 Injuries to the thorax	0.889	0.111
S90-S99 Injuries to the ankle and foot	0.887	0.113
G80-G83 Cerebral palsy and other paralytic syndromes	0.885	0.115
G50-G59 Nerve, nerve root and plexus disorders	0.884	0.116
O94-O99 Other obstetric conditions, not elsewhere classified	0.881	0.119
C18.6 Descending colon	0.876	0.124
F10.0 Acute intoxication	0.876	0.124
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.875	0.125
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.875	0.125
M79.0 Rheumatism, unspecified	0.874	0.126
S42 Fracture of shoulder and upper arm	0.871	0.129
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.871	0.129
F60-F69 Disorders of adult personality and behaviour	0.870	0.130
M25 Other joint disorders, not elsewhere classified	0.868	0.132
D36 Benign neoplasm of other and unspecified sites	0.862	0.138
S81.0 Open wound of knee	0.862	0.138
E10 Insulin-dependent diabetes mellitus	0.860	0.140
M79.8 Other specified soft tissue disorders	0.858	0.142
M79.60 Pain in limb (Multiple sites)	0.857	0.143
D12.6 Colon, unspecified	0.856	0.144
G57 Mononeuropathies of lower limb	0.849	0.151
O85-O92 Complications predominantly related to the puerperium	0.847	0.153
M79.67 Pain in limb (Ankle and foot)	0.846	0.154
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.846	0.154
S19 Other and unspecified injuries of neck	0.844	0.156
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.842	0.158
D34 Benign neoplasm of thyroid gland	0.841	0.159
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.836	0.164
D32 Benign neoplasm of meninges	0.835	0.165
O20-O29 Other maternal disorders predominantly related to pregnancy	0.834	0.166
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.834	0.166
E27 Other disorders of adrenal gland	0.832	0.168
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.829	0.171
H60 Otitis externa	0.829	0.171
H61.0 Perichondritis of external ear	0.828	0.172
M50-M54 Other dorsopathies	0.824	0.176
G57.6 Lesion of plantar nerve	0.820	0.180
E53 Deficiency of other B group vitamins	0.816	0.184
M79.65 Pain in limb (Pelvic region and thigh)	0.816	0.184
T43.5 Other and unspecified antipsychotics and neuroleptics	0.816	0.184
M24 Other specific joint derangements	0.815	0.185
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.814	0.186
S82 Fracture of lower leg, including ankle	0.812	0.188
W00-W19 Falls	0.812	0.188
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.809	0.191
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.808	0.192
D46 Myelodysplastic syndromes	0.807	0.193
M22 Disorders of patella	0.807	0.193
E65-E68 Obesity and other hyperalimentation	0.806	0.194
M45-M49 Spondylopathies	0.805	0.195
S80 Superficial injury of lower leg	0.801	0.199
M79.09 Rheumatism, unspecified (Site unspecified)	0.800	0.200
G81 Hemiplegia	0.800	0.200
H61.2 Impacted cerumen	0.799	0.201
F12 Mental and behavioural disorders due to use of cannabinoids	0.798	0.202
S31 Open wound of abdomen, lower back and pelvis	0.795	0.205
T43.3 Phenothiazine antipsychotics and neuroleptics	0.795	0.205
M77 Other enthesopathies	0.794	0.206
D00-D09 In situ neoplasms	0.793	0.207
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.793	0.207
X40-X49 Accidental poisoning by and exposure to noxious substances	0.792	0.208
C26 Malignant neoplasm of other and ill-defined digestive organs	0.792	0.208
T43.0 Tricyclic and tetracyclic antidepressants	0.791	0.209
F80-F89 Disorders of psychological development	0.791	0.209
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.791	0.209
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.790	0.210
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.789	0.211
E23.2 Diabetes insipidus	0.787	0.213
S46 Injury of muscle and tendon at shoulder and upper arm level	0.787	0.213
E23.0 Hypopituitarism	0.785	0.215
E10.3 With ophthalmic complications	0.782	0.218
S42.2 Fracture of upper end of humerus	0.781	0.219
T43.2 Other and unspecified antidepressants	0.780	0.220
M35 Other systemic involvement of connective tissue	0.780	0.220
S19.9 Unspecified injury of neck	0.778	0.222
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.778	0.222
M95.0 Acquired deformity of nose	0.777	0.223
C64-C68 Malignant neoplasms of urinary tract	0.775	0.225
C18.1 Appendix	0.774	0.226
M79.61 Pain in limb (Shoulder region)	0.774	0.226
T79-T79 Certain early complications of trauma	0.771	0.229
M25.4 Effusion of joint	0.771	0.229
G70-G73 Diseases of myoneural junction and muscle	0.771	0.229
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.770	0.230
F10.2 Dependence syndrome	0.770	0.230
E10.4 With neurological complications	0.770	0.230
O20 Haemorrhage in early pregnancy	0.770	0.230
M80-M85 Disorders of bone density and structure	0.768	0.232
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.768	0.232
C18.2 Ascending colon	0.768	0.232
D12.3 Transverse colon	0.767	0.233
C23 Malignant neoplasm of gallbladder	0.766	0.234
T46 Poisoning by agents primarily affecting the cardiovascular system	0.766	0.234
T42.1 Iminostilbenes	0.765	0.235
M25.7 Osteophyte	0.765	0.235
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.764	0.236
O03 Spontaneous abortion	0.764	0.236
G59 Mononeuropathy in diseases classified elsewhere	0.763	0.237
D35 Benign neoplasm of other and unspecified endocrine glands	0.762	0.238
G58 Other mononeuropathies	0.761	0.239
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.761	0.239
E61 Deficiency of other nutrient elements	0.760	0.240
S40 Superficial injury of shoulder and upper arm	0.760	0.240
D36.7 Other specified sites	0.760	0.240
V20-V29 Motorcycle rider injured in transport accident	0.759	0.241
T20-T25 Burns and corrosions of external body surface, specified by site	0.759	0.241
M91-M94 Chondropathies	0.758	0.242
C25 Malignant neoplasm of pancreas	0.757	0.243
D16 Benign neoplasm of bone and articular cartilage	0.756	0.244
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.756	0.244
G82 Paraplegia and tetraplegia	0.756	0.244
M15-M19 Arthrosis	0.755	0.245
E11 Non-insulin-dependent diabetes mellitus	0.755	0.245
F60 Specific personality disorders	0.753	0.247
D12.8 Rectum	0.753	0.247
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.753	0.247
W50-W64 Exposure to animate mechanical forces	0.753	0.247
S12 Fracture of neck	0.752	0.248
H61.9 Disorder of external ear, unspecified	0.751	0.249
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.750	0.250
M79.62 Pain in limb (Upper arm)	0.750	0.250
D12.2 Ascending colon	0.750	0.250
M60-M63 Disorders of muscles	0.749	0.250
T15-T19 Effects of foreign body entering through natural orifice	0.749	0.251
M51 Other intervertebral disk disorders	0.748	0.252
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.747	0.253
T39.1 4-Aminophenol derivatives	0.747	0.253
S10 Superficial injury of neck	0.746	0.254
S27 Injury of other and unspecified intrathoracic organs	0.745	0.255
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.745	0.255
W19 Unspecified fall	0.744	0.256
E53.8 Deficiency of other specified B group vitamins	0.743	0.257
M79.1 Myalgia	0.742	0.258
O04 Medical abortion	0.742	0.258
F99-F99 Unspecified mental disorder	0.742	0.258
X60-X84 Intentional self-harm	0.742	0.258
S41 Open wound of shoulder and upper arm	0.742	0.258
D22 Melanocytic naevi	0.741	0.259
M79.84 Other specified soft tissue disorders (Hand)	0.741	0.259
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.739	0.261
G81.9 Hemiplegia, unspecified	0.739	0.261
D47.3 Essential (haemorrhagic) thrombocythaemia	0.739	0.261
H61.3 Acquired stenosis of external ear canal	0.738	0.262
U80 Agent resistant to penicillin and related antibiotics	0.737	0.263
D21 Other benign neoplasms of connective and other soft tissue	0.737	0.263
O86 Other puerperal infections	0.735	0.265
S81.9 Open wound of lower leg, part unspecified	0.734	0.266
C18.3 Hepatic flexure	0.734	0.266
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.731	0.269
M79.4 Hypertrophy of (infrapatellar) fat pad	0.731	0.269
C80 Malignant neoplasm without specification of site	0.729	0.271
D30 Benign neoplasm of urinary organs	0.728	0.272
M22.8 Other disorders of patella	0.728	0.272
E40-E46 Malnutrition	0.727	0.273
T51 Toxic effect of alcohol	0.727	0.273
M25.9 Joint disorder, unspecified	0.725	0.275
C49 Malignant neoplasm of other connective and soft tissue	0.725	0.275
S22 Fracture of rib(s), sternum and thoracic spine	0.725	0.275
M24.1 Other articular cartilage disorders	0.725	0.275
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.722	0.277
D48.5 Skin	0.722	0.278
E24 Cushing's syndrome	0.722	0.278
S92 Fracture of foot, except ankle	0.722	0.278
M31 Other necrotising vasculopathies	0.719	0.281
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.719	0.281
S42.20 Fracture of upper end of humerus (closed)	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.717	0.283
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283
T36 Poisoning by systemic antibiotics	0.717	0.283
S43.0 Dislocation of shoulder joint	0.716	0.284
M79.83 Other specified soft tissue disorders (Forearm)	0.716	0.284
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.715	0.285
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.715	0.285
D48.7 Other specified sites	0.714	0.286
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
F10.3 Withdrawal state	0.714	0.286
S42.9 Fracture of shoulder girdle, part unspecified	0.714	0.286
M51.2 Other specified intervertebral disk displacement	0.711	0.289
M76 Enthesopathies of lower limb, excluding foot	0.711	0.289
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.710	0.290
S80.9 Superficial injury of lower leg, unspecified	0.710	0.290
C21 Malignant neoplasm of anus and anal canal	0.710	0.290
C17 Malignant neoplasm of small intestine	0.710	0.290
M25.76 Osteophyte (Lower leg)	0.710	0.290
G80 Infantile cerebral palsy	0.709	0.291
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.709	0.291
H94 Other disorders of ear in diseases classified elsewhere	0.709	0.291
D48.1 Connective and other soft tissue	0.708	0.292
E28 Ovarian dysfunction	0.707	0.292
H91.8 Other specified hearing loss	0.707	0.293
H91.3 Deaf mutism, not elsewhere classified	0.707	0.293
H91.2 Sudden idiopathic hearing loss	0.707	0.293
H91.1 Presbycusis	0.707	0.293
H91.0 Ototoxic hearing loss	0.707	0.293
F69 Unspecified disorder of adult personality and behaviour	0.707	0.293
E55 Vitamin D deficiency	0.706	0.294
C18.8 Overlapping lesion of colon	0.706	0.294
M73 Soft tissue disorders in diseases classified elsewhere	0.706	0.294
H80-H83 Diseases of inner ear	0.706	0.294
D12.0 Caecum	0.705	0.295
M30 Polyarteritis nodosa and related conditions	0.705	0.295
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.704	0.296
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.703	0.297
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.703	0.297
T42.5 Mixed antiepileptics, not elsewhere classified	0.703	0.297
T42.3 Barbiturates	0.703	0.297
T42.2 Succinimides and oxazolidinediones	0.703	0.297
T42.0 Hydantoin derivatives	0.703	0.297
O20.0 Threatened abortion	0.703	0.297
H65-H75 Diseases of middle ear and mastoid	0.702	0.298
X58-X59 Accidental exposure to other and unspecified factors	0.702	0.298
F10.1 Harmful use	0.702	0.298
D46.9 Myelodysplastic syndrome, unspecified	0.701	0.299
D04 Carcinoma in situ of skin	0.701	0.299
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.700	0.300
F70-F79 Mental retardation	0.700	0.300
M79.2 Neuralgia and neuritis, unspecified	0.700	0.300
M79.9 Soft tissue disorder, unspecified	0.699	0.301
M79.3 Panniculitis, unspecified	0.699	0.301
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.698	0.302
E22 Hyperfunction of pituitary gland	0.698	0.302
M75 Shoulder lesions	0.697	0.303
S48 Traumatic amputation of shoulder and upper arm	0.696	0.304
S45 Injury of blood vessels at shoulder and upper arm level	0.696	0.304
S44 Injury of nerves at shoulder and upper arm level	0.696	0.304
S47 Crushing injury of shoulder and upper arm	0.696	0.304
H62 Disorders of external ear in diseases classified elsewhere	0.696	0.304
S82.4 Fracture of fibula alone	0.694	0.306
M00-M03 Infectious arthropathies	0.694	0.306
C18.5 Splenic flexure	0.694	0.306
M21 Other acquired deformities of limbs	0.694	0.306
E35 Disorders of endocrine glands in diseases classified elsewhere	0.692	0.307
E34 Other endocrine disorders	0.692	0.307
E32 Diseases of thymus	0.692	0.307
E31 Polyglandular dysfunction	0.692	0.307
E30 Disorders of puberty, not elsewhere classified	0.692	0.307
E26 Hyperaldosteronism	0.692	0.307
E25 Adrenogenital disorders	0.692	0.307
E20 Hypoparathyroidism	0.692	0.307
W19.2 School, other institution and public administrative area	0.692	0.308
S31.4 Open wound of vagina and vulva	0.692	0.308
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.692	0.308
F12.1 Harmful use	0.691	0.309
S88 Traumatic amputation of lower leg	0.691	0.309
S87 Crushing injury of lower leg	0.691	0.309
S85 Injury of blood vessels at lower leg level	0.691	0.309
S84 Injury of nerves at lower leg level	0.691	0.309
H60.9 Otitis externa, unspecified	0.691	0.309
M25.46 Effusion of joint (Lower leg)	0.689	0.311
S82.2 Fracture of shaft of tibia	0.689	0.311
D32.9 Meninges, unspecified	0.689	0.311
M71 Other bursopathies	0.688	0.311
E21.3 Hyperparathyroidism, unspecified	0.688	0.312
S86 Injury of muscle and tendon at lower leg level	0.688	0.312
M34 Systemic sclerosis	0.687	0.313
S89 Other and unspecified injuries of lower leg	0.685	0.315
T43.9 Psychotropic drug, unspecified	0.685	0.315
T43.8 Other psychotropic drugs, not elsewhere classified	0.685	0.315
T43.6 Psychostimulants with abuse potential	0.685	0.315
T43.4 Butyrophenone and thioxanthene neuroleptics	0.685	0.315
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.685	0.315
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.684	0.316
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.684	0.316
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.684	0.316
S20 Superficial injury of thorax	0.684	0.316
E14 Unspecified diabetes mellitus	0.684	0.316
D32.1 Spinal meninges	0.683	0.317
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.683	0.317
D31 Benign neoplasm of eye and adnexa	0.683	0.317
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.683	0.317
D19 Benign neoplasm of mesothelial tissue	0.683	0.317
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.683	0.317
D36.0 Lymph nodes	0.683	0.317
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.682	0.318
O08 Complications following abortion and ectopic and molar pregnancy	0.682	0.318
O07 Failed attempted abortion	0.682	0.318
O06 Unspecified abortion	0.682	0.318
O05 Other abortion	0.682	0.318
O01 Hydatidiform mole	0.682	0.318
D28 Benign neoplasm of other and unspecified female genital organs	0.682	0.318
E10.8 With unspecified complications	0.681	0.319
M46 Other inflammatory spondylopathies	0.681	0.319
H61.1 Non-infective disorders of pinna	0.680	0.320
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.680	0.320
F18 Mental and behavioural disorders due to use of volatile solvents	0.680	0.320
F16 Mental and behavioural disorders due to use of hallucinogens	0.680	0.320
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.680	0.320
F14 Mental and behavioural disorders due to use of cocaine	0.680	0.320
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.680	0.320
F11 Mental and behavioural disorders due to use of opioids	0.680	0.320
D12.4 Descending colon	0.679	0.320
D14 Benign neoplasm of middle ear and respiratory system	0.679	0.321
S49 Other and unspecified injuries of shoulder and upper arm	0.678	0.322
M18 Arthrosis of first carpometacarpal joint	0.677	0.323
G59.0 Diabetic mononeuropathy	0.676	0.323
D12.1 Appendix	0.676	0.324
E29 Testicular dysfunction	0.676	0.324
M47 Spondylosis	0.675	0.325
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.674	0.326
G53 Cranial nerve disorders in diseases classified elsewhere	0.674	0.326
M79.68 Pain in limb (Other)	0.673	0.327
T50.8 Diagnostic agents	0.673	0.327
T50.7 Analeptics and opioid receptor antagonists	0.673	0.327
T50.6 Antidotes and chelating agents, not elsewhere classified	0.673	0.327
T50.5 Appetite depressants	0.673	0.327
T50.4 Drugs affecting uric acid metabolism	0.673	0.327
T50.3 Electrolytic, caloric and water-balance agents	0.673	0.327
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.673	0.327
T50.1 Loop [high-ceiling] diuretics	0.673	0.327
T50.0 Mineralocorticoids and their antagonists	0.673	0.327
S46.2 Injury of muscle and tendon of other parts of biceps	0.672	0.328
S17 Crushing injury of neck	0.672	0.328
S15 Injury of blood vessels at neck level	0.672	0.328
S14 Injury of nerves and spinal cord at neck level	0.672	0.328
S11 Open wound of neck	0.672	0.328
S18 Traumatic amputation at neck level	0.672	0.328
S16 Injury of muscle and tendon at neck level	0.672	0.328
D22.6 Melanocytic naevi of upper limb, including shoulder	0.671	0.329
S31.8 Open wound of other and unspecified parts of abdomen	0.670	0.330
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.670	0.330
M33 Dermatopolymyositis	0.670	0.330
M32 Systemic lupus erythematosus	0.670	0.330
D29 Benign neoplasm of male genital organs	0.670	0.330
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.670	0.330
M66 Spontaneous rupture of synovium and tendon	0.670	0.330
E66 Obesity	0.670	0.330
S43.1 Dislocation of acromioclavicular joint	0.668	0.331
X10-X19 Contact with heat and hot substances	0.668	0.332
C18.4 Transverse colon	0.668	0.332
G50 Disorders of trigeminal nerve	0.667	0.333
E11.4 With neurological complications	0.667	0.333
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.666	0.334
S32 Fracture of lumbar spine and pelvis	0.666	0.334
E12 Malnutrition-related diabetes mellitus	0.666	0.334
M86-M90 Other osteopathies	0.664	0.336
M77.0 Medial epicondylitis	0.664	0.336
F10.4 Withdrawal state with delirium	0.663	0.336
C80.0 Malignant neoplasm, primary site unknown, so stated	0.663	0.337
F10.9 Unspecified mental and behavioural disorder	0.661	0.339
F10.8 Other mental and behavioural disorders	0.661	0.339
F10.7 Residual and late-onset psychotic disorder	0.661	0.339
F10.6 Amnesic syndrome	0.661	0.339
F10.5 Psychotic disorder	0.661	0.339
M50 Cervical disk disorders	0.661	0.339
D47.2 Monoclonal gammopathy	0.661	0.339
S42.3 Fracture of shaft of humerus	0.660	0.340
G12 Spinal muscular atrophy and related syndromes	0.660	0.340
E27.8 Other specified disorders of adrenal gland	0.660	0.340
E64 Sequelae of malnutrition and other nutritional deficiencies	0.659	0.341
E63 Other nutritional deficiencies	0.659	0.341
E56 Other vitamin deficiencies	0.659	0.341
E51 Thiamine deficiency	0.659	0.341
E50 Vitamin A deficiency	0.659	0.341
E60 Dietary zinc deficiency	0.659	0.341
E59 Dietary selenium deficiency	0.659	0.341
E58 Dietary calcium deficiency	0.659	0.341
E54 Ascorbic acid deficiency	0.659	0.341
E52 Niacin deficiency [pellagra]	0.659	0.341
M99 Biomechanical lesions, not elsewhere classified	0.659	0.341
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.659	0.341
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.658	0.342
S91 Open wound of ankle and foot	0.658	0.342
G57.1 Meralgia paraesthetica	0.658	0.342
M79.89 Other specified soft tissue disorders (Site unspecified)	0.658	0.342
V40-V49 Car occupant injured in transport accident	0.657	0.342
H60.1 Cellulitis of external ear	0.657	0.343
G58.8 Other specified mononeuropathies	0.657	0.343
D18 Haemangioma and lymphangioma, any site	0.656	0.344
C80.9 Malignant neoplasm, unspecified	0.656	0.344
M05-M14 Inflammatory polyarthropathies	0.656	0.344
E27.9 Disorder of adrenal gland, unspecified	0.656	0.344
O02.9 Abnormal product of conception, unspecified	0.656	0.344
O02.8 Other specified abnormal products of conception	0.656	0.344
M75.0 Adhesive capsulitis of shoulder	0.656	0.344
O00 Ectopic pregnancy	0.655	0.345
W55 Bitten or struck by other mammals	0.655	0.345
E27.1 Primary adrenocortical insufficiency	0.655	0.345
D22.4 Melanocytic naevi of scalp and neck	0.654	0.346
U80.1 Methicillin resistant agent	0.654	0.346
D36.1 Peripheral nerves and autonomic nervous system	0.654	0.346
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.654	0.346
M35.3 Polymyalgia rheumatica	0.654	0.346
D24 Benign neoplasm of breast	0.653	0.347
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.653	0.347
M72 Fibroblastic disorders	0.653	0.347
S93.1 Dislocation of toe(s)	0.653	0.347
M67.9 Disorder of synovium and tendon, unspecified	0.652	0.348
M67.4 Ganglion	0.652	0.348
M67.3 Transient synovitis	0.652	0.348
M67.1 Other contracture of tendon (sheath)	0.652	0.348
M67.0 Short Achilles tendon (acquired)	0.652	0.348
X41.9 Unspecified place	0.652	0.348
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.650	0.349
T51.0 Ethanol	0.650	0.350
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.650	0.350
C20 Malignant neoplasm of rectum	0.650	0.350
S81.7 Multiple open wounds of lower leg	0.650	0.350
C26.0 Intestinal tract, part unspecified	0.649	0.351
M79.7 Fibromyalgia	0.648	0.352
D48.6 Breast	0.648	0.352
E61.1 Iron deficiency	0.646	0.354
D48.0 Bone and articular cartilage	0.645	0.355
M22.3 Other derangements of patella	0.645	0.355
D33 Benign neoplasm of brain and other parts of central nervous system	0.645	0.355
O87 Venous complications in the puerperium	0.644	0.356
E23.7 Disorder of pituitary gland, unspecified	0.643	0.356
E23.6 Other disorders of pituitary gland	0.643	0.356
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.643	0.356
E23.1 Drug-induced hypopituitarism	0.643	0.356
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.644	0.356
E13 Other specified diabetes mellitus	0.643	0.356
D10 Benign neoplasm of mouth and pharynx	0.642	0.358
F25 Schizoaffective disorders	0.641	0.359
M67.2 Synovial hypertrophy, not elsewhere classified	0.639	0.361
T45.0 Antiallergic and antiemetic drugs	0.639	0.361
S90 Superficial injury of ankle and foot	0.638	0.362
Y35-Y36 Legal intervention and operations of war	0.638	0.362
Y10-Y34 Event of undetermined intent	0.638	0.362
Y00-Y09 Assault	0.638	0.362
X85-X99 Assault	0.638	0.362
X30-X39 Exposure to forces of nature	0.638	0.362
X00-X09 Exposure to smoke, fire and flames	0.638	0.362
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.638	0.362
W75-W84 Other accidental threats to breathing	0.638	0.362
W65-W74 Accidental drowning and submersion	0.638	0.362
V98-V99 Other and unspecified transport accidents	0.638	0.362
V95-V97 Air and space transport accidents	0.638	0.362
V90-V94 Water transport accidents	0.638	0.362
V70-V79 Bus occupant injured in transport accident	0.638	0.362
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.638	0.362
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.638	0.362
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.638	0.362
V01-V09 Pedestrian injured in transport accident	0.638	0.362
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.637	0.363
S26 Injury of heart	0.637	0.363
S25 Injury of blood vessels of thorax	0.637	0.363
S24 Injury of nerves and spinal cord at thorax level	0.637	0.363
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.637	0.363
S21 Open wound of thorax	0.637	0.363
D47.4 Osteomyelofibrosis	0.637	0.363
H92 Otalgia and effusion of ear	0.637	0.363

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations