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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77141874
log Bayes Factor = 14.9976
Chromosome 6   position 55,438,094  (GRCh37) Explore rs77141874 on Ensembl!
Variant rs77141874 is part of Cluster X0275

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M20 Acquired deformities of fingers and toes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
J45.9 Asthma, unspecified
0.999 0.001 0.000
J45 Asthma
0.999 0.001 0.000
M25 Other joint disorders, not elsewhere classified
0.998 0.002 0.000
M25.5 Pain in joint
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.996 0.004 0.000
M25.56 Pain in joint (Lower leg)
0.995 0.005 0.000
J30-J39 Other diseases of upper respiratory tract
0.995 0.005 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.989 0.011 0.000
M15-M19 Arthrosis
0.986 0.014 0.000
M79.6 Pain in limb
0.986 0.014 0.000
M20.2 Hallux rigidus
0.982 0.018 0.000
M20.4 Other hammer toe(s) (acquired)
0.979 0.021 0.000
M19 Other arthrosis
0.978 0.022 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
M79.66 Pain in limb (Lower leg)
0.975 0.025 0.000
N40-N51 Diseases of male genital organs
0.975 0.025 0.000
J32 Chronic sinusitis
0.971 0.029 0.000
M05-M14 Inflammatory polyarthropathies
0.971 0.029 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
M20.5 Other deformities of toe(s) (acquired)
0.966 0.034 0.000
M19.9 Arthrosis, unspecified
0.965 0.035 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.962 0.038 0.000
N72 Inflammatory disease of cervix uteri
0.955 0.045 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.952 0.048 0.000
J34 Other disorders of nose and nasal sinuses
0.947 0.053 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.947 0.053 0.000
N50 Other disorders of male genital organs
0.946 0.054 0.000
B95-B98 Bacterial, viral and other infectious agents
0.944 0.056 0.000
N80 Endometriosis
0.941 0.059 0.000
N70 Salpingitis and oophoritis
0.932 0.068 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.929 0.071 0.000
M50-M54 Other dorsopathies
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.920 0.080 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.916 0.084 0.000
J34.2 Deviated nasal septum
0.911 0.089 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.900 0.100 0.000
N50.8 Other specified disorders of male genital organs
0.900 0.100 0.000
M24 Other specific joint derangements
0.887 0.113 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.887 0.113 0.000
G40-G47 Episodic and paroxysmal disorders
0.887 0.113 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.886 0.114 0.000
M54 Dorsalgia
0.883 0.117 0.000
J32.9 Chronic sinusitis, unspecified
0.879 0.121 0.000
A30-A49 Other bacterial diseases
0.876 0.124 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.873 0.127 0.000
J30 Vasomotor and allergic rhinitis
0.872 0.128 0.000
M45-M49 Spondylopathies
0.872 0.128 0.000
J32.0 Chronic maxillary sinusitis
0.869 0.131 0.000
M23 Internal derangement of knee
0.867 0.133 0.000
N00-N08 Glomerular diseases
0.865 0.135 0.000
N80.3 Endometriosis of pelvic peritoneum
0.864 0.136 0.000
M05 Seropositive rheumatoid arthritis
0.864 0.136 0.000
M06 Other rheumatoid arthritis
0.861 0.139 0.000
M19.94 Arthrosis, unspecified (Hand)
0.842 0.158 0.000
N70.1 Chronic salpingitis and oophoritis
0.838 0.162 0.000
N50.1 Vascular disorders of male genital organs
0.831 0.169 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.831 0.169 0.000
M21 Other acquired deformities of limbs
0.830 0.170 0.000
N93 Other abnormal uterine and vaginal bleeding
0.830 0.170 0.000
M79.69 Pain in limb (Site unspecified)
0.829 0.171 0.000
G47 Sleep disorders
0.828 0.172 0.000
W20-W49 Exposure to inanimate mechanical forces
0.827 0.173 0.000
A00-A09 Intestinal infectious diseases
0.827 0.173 0.000
V80-V89 Other land transport accidents
0.826 0.174 0.000
S70-S79 Injuries to the hip and thigh
0.825 0.175 0.000
N80.0 Endometriosis of uterus
0.825 0.175 0.000
N86 Erosion and ectropion of cervix uteri
0.822 0.178 0.000
M79.0 Rheumatism, unspecified
0.821 0.179 0.000
N97 Female infertility
0.820 0.180 0.000
M47 Spondylosis
0.818 0.182 0.000
M24.0 Loose body in joint
0.817 0.183 0.000
J40 Bronchitis, not specified as acute or chronic
0.817 0.183 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.817 0.183 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.816 0.184 0.000
M79.1 Myalgia
0.814 0.186 0.000
M17 Gonarthrosis [arthrosis of knee]
0.813 0.187 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.813 0.187 0.000
M13 Other arthritis
0.813 0.187 0.000
N40 Hyperplasia of prostate
0.812 0.188 0.000
T43.2 Other and unspecified antidepressants
0.811 0.189 0.000
M25.54 Pain in joint (Hand)
0.811 0.189 0.000
M25.8 Other specified joint disorders
0.810 0.190 0.000
M79.7 Fibromyalgia
0.806 0.194 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.805 0.195 0.000
N80.9 Endometriosis, unspecified
0.804 0.196 0.000
G56 Mononeuropathies of upper limb
0.803 0.197 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.800 0.200 0.000
M77 Other enthesopathies
0.799 0.201 0.000
M31 Other necrotising vasculopathies
0.798 0.202 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.795 0.205 0.000
M25.57 Pain in joint (Ankle and foot)
0.795 0.205 0.000
M79.67 Pain in limb (Ankle and foot)
0.793 0.207 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.791 0.209 0.000
M19.1 Posttraumatic arthrosis of other joints
0.791 0.209 0.000
B35-B49 Mycoses
0.791 0.209 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.791 0.209 0.000
J32.2 Chronic ethmoidal sinusitis
0.791 0.209 0.000
A41 Other septicaemia
0.790 0.210 0.000
M19.0 Primary arthrosis of other joints
0.789 0.211 0.000
J34.3 Hypertrophy of nasal turbinates
0.789 0.211 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.787 0.213 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.781 0.219 0.000
M47.8 Other spondylosis
0.781 0.219 0.000
J44 Other chronic obstructive pulmonary disease
0.778 0.222 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.777 0.223 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.776 0.224 0.000
Y40 Systemic antibiotics
0.775 0.225 0.000
M79.62 Pain in limb (Upper arm)
0.774 0.226 0.000
M54.5 Low back pain
0.772 0.228 0.000
N80.1 Endometriosis of ovary
0.772 0.228 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.771 0.229 0.000
J30.1 Allergic rhinitis due to pollen
0.771 0.229 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.770 0.230 0.000
G56.0 Carpal tunnel syndrome
0.768 0.232 0.000
G47.3 Sleep apnoea
0.767 0.233 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.766 0.234 0.000
N84 Polyp of female genital tract
0.764 0.236 0.000
J90-J94 Other diseases of pleura
0.763 0.236 0.000
M07 Psoriatic and enteropathic arthropathies
0.763 0.237 0.000
Q60-Q64 Congenital malformations of the urinary system
0.763 0.237 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.762 0.238 0.000
N20-N23 Urolithiasis
0.761 0.239 0.000
N73 Other female pelvic inflammatory diseases
0.760 0.240 0.000
J32.8 Other chronic sinusitis
0.759 0.241 0.000
J45.0 Predominantly allergic asthma
0.759 0.241 0.000
N42 Other disorders of prostate
0.758 0.242 0.000
M20.0 Deformity of finger(s)
0.758 0.242 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.753 0.246 0.000
N03 Chronic nephritic syndrome
0.751 0.249 0.000
M06.9 Rheumatoid arthritis, unspecified
0.750 0.250 0.000
N48 Other disorders of penis
0.749 0.251 0.000
M54.9 Dorsalgia, unspecified
0.749 0.251 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.748 0.252 0.000
G90-G99 Other disorders of the nervous system
0.748 0.252 0.000
X60-X84 Intentional self-harm
0.748 0.252 0.000
G43 Migraine
0.748 0.252 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.746 0.254 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.745 0.255 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.745 0.255 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.744 0.256 0.000
N71 Inflammatory disease of uterus, except cervix
0.744 0.256 0.000
N80.8 Other endometriosis
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.741 0.259 0.000
M47.86 Other spondylosis (Lumbar region)
0.740 0.260 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.740 0.260 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.738 0.262 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
N43 Hydrocele and spermatocele
0.736 0.263 0.000
J00-J06 Acute upper respiratory infections
0.736 0.264 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.734 0.266 0.000
V20-V29 Motorcycle rider injured in transport accident
0.734 0.266 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.730 0.270 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.729 0.271 0.000
A80-A89 Viral infections of the central nervous system
0.729 0.271 0.000
Q00-Q07 Congenital malformations of the nervous system
0.729 0.271 0.000
M24.02 Loose body in joint (Upper arm)
0.727 0.273 0.000
J43 Emphysema
0.727 0.273 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.726 0.273 0.000
N89 Other noninflammatory disorders of vagina
0.726 0.274 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.726 0.274 0.000
N97.9 Female infertility, unspecified
0.725 0.275 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.725 0.275 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.724 0.275 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.724 0.276 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.722 0.278 0.000
N76 Other inflammation of vagina and vulva
0.721 0.279 0.000
M20.3 Other deformity of hallux (acquired)
0.720 0.279 0.000
M86-M90 Other osteopathies
0.720 0.280 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.720 0.280 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.720 0.280 0.000
M79.64 Pain in limb (Hand)
0.718 0.282 0.000
N45 Orchitis and epididymitis
0.718 0.282 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.283 0.000
J45.8 Mixed asthma
0.716 0.283 0.000
J45.1 Nonallergic asthma
0.716 0.283 0.000
M25.9 Joint disorder, unspecified
0.716 0.284 0.000
M25.3 Other instability of joint
0.716 0.284 0.000
M25.2 Flail joint
0.716 0.284 0.000
M25.1 Fistula of joint
0.716 0.284 0.000
M25.0 Haemarthrosis
0.716 0.284 0.000
M79.5 Residual foreign body in soft tissue
0.716 0.284 0.000
M25.59 Pain in joint (Site unspecified)
0.715 0.285 0.000
M25.58 Pain in joint (Other)
0.715 0.285 0.000
M25.52 Pain in joint (Upper arm)
0.715 0.285 0.000
M76 Enthesopathies of lower limb, excluding foot
0.714 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.714 0.286 0.000
M71 Other bursopathies
0.714 0.286 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
J37 Chronic laryngitis and laryngotracheitis
0.713 0.287 0.000
M79.60 Pain in limb (Multiple sites)
0.713 0.287 0.000
M54.3 Sciatica
0.712 0.287 0.000
M79.9 Soft tissue disorder, unspecified
0.712 0.288 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.712 0.288 0.000
M79.3 Panniculitis, unspecified
0.712 0.288 0.000
M79.2 Neuralgia and neuritis, unspecified
0.712 0.288 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
Y52 Agents primarily affecting the cardiovascular system
0.711 0.289 0.000
S40-S49 Injuries to the shoulder and upper arm
0.710 0.290 0.000
M23.8 Other internal derangements of knee
0.710 0.290 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.709 0.291 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.709 0.291 0.000
A04 Other bacterial intestinal infections
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
M54.1 Radiculopathy
0.708 0.292 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.707 0.293 0.000
M15 Polyarthrosis
0.707 0.293 0.000
M79.68 Pain in limb (Other)
0.707 0.293 0.000
M79.63 Pain in limb (Forearm)
0.707 0.293 0.000
M79.61 Pain in limb (Shoulder region)
0.707 0.293 0.000
T66-T78 Other and unspecified effects of external causes
0.706 0.294 0.000
M18 Arthrosis of first carpometacarpal joint
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
Q80-Q89 Other congenital malformations
0.704 0.296 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.704 0.296 0.000
W22 Striking against or struck by other objects
0.703 0.297 0.000
M21.1 Varus deformity, not elsewhere classified
0.703 0.297 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.703 0.297 0.000
Q50-Q56 Congenital malformations of genital organs
0.703 0.297 0.000
M17.0 Primary gonarthrosis, bilateral
0.703 0.297 0.000
J38.3 Other diseases of vocal cords
0.701 0.299 0.000
M19.8 Other specified arthrosis
0.701 0.299 0.000
M19.2 Other secondary arthrosis
0.701 0.299 0.000
G51 Facial nerve disorders
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.699 0.300 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.699 0.301 0.000
N46 Male infertility
0.699 0.301 0.000
N44 Torsion of testis
0.699 0.301 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.698 0.302 0.000
N17-N19 Renal failure
0.698 0.302 0.000
M13.9 Arthritis, unspecified
0.698 0.302 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.697 0.303 0.000
M25.50 Pain in joint (Multiple sites)
0.696 0.304 0.000
J32.4 Chronic pansinusitis
0.696 0.304 0.000
J32.3 Chronic sphenoidal sinusitis
0.696 0.304 0.000
J32.1 Chronic frontal sinusitis
0.696 0.304 0.000
M14 Arthropathies in other diseases classified elsewhere
0.696 0.304 0.000
M12 Other specific arthropathies
0.696 0.304 0.000
M11 Other crystal arthropathies
0.696 0.304 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.696 0.304 0.000
M08 Juvenile arthritis
0.696 0.304 0.000
B02 Zoster [herpes zoster]
0.696 0.304 0.000
M47.82 Other spondylosis (Cervical region)
0.695 0.305 0.000
G20-G26 Extrapyramidal and movement disorders
0.695 0.305 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.693 0.307 0.000
M23.3 Other meniscus derangements
0.693 0.307 0.000
N84.0 Polyp of corpus uteri
0.691 0.309 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.691 0.309 0.000
M24.07 Loose body in joint (Ankle and foot)
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.689 0.310 0.000
T33-T35 Frostbite
0.689 0.310 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.689 0.310 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.689 0.310 0.000
T00-T07 Injuries involving multiple body regions
0.689 0.310 0.000
S10-S19 Injuries to the neck
0.689 0.310 0.000
M79.8 Other specified soft tissue disorders
0.689 0.311 0.000
N93.0 Postcoital and contact bleeding
0.688 0.312 0.000
M06.0 Seronegative rheumatoid arthritis
0.688 0.312 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.687 0.312 0.000
Y54.3 Benzothiadiazine derivatives
0.687 0.313 0.000
M79.19 Myalgia (Site unspecified)
0.686 0.314 0.000
J42 Unspecified chronic bronchitis
0.685 0.315 0.000
G57 Mononeuropathies of lower limb
0.684 0.316 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.683 0.317 0.000
N98 Complications associated with artificial fertilisation
0.683 0.317 0.000
N91 Absent, scanty and rare menstruation
0.683 0.317 0.000
N82 Fistulae involving female genital tract
0.683 0.317 0.000
N96 Habitual aborter
0.683 0.317 0.000
M22 Disorders of patella
0.683 0.317 0.000
S72 Fracture of femur
0.682 0.318 0.000
M70.6 Trochanteric bursitis
0.682 0.318 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.681 0.318 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.681 0.319 0.000
S90-S99 Injuries to the ankle and foot
0.681 0.319 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.680 0.320 0.000
J36 Peritonsillar abscess
0.680 0.320 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.679 0.321 0.000
M25.7 Osteophyte
0.679 0.321 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.679 0.321 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.679 0.321 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.679 0.321 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.679 0.321 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.321 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.679 0.321 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.679 0.321 0.000
T36 Poisoning by systemic antibiotics
0.679 0.321 0.000
N50.9 Disorder of male genital organs, unspecified
0.679 0.321 0.000
N50.0 Atrophy of testis
0.679 0.321 0.000
M19.98 Arthrosis, unspecified (Other)
0.678 0.322 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.678 0.322 0.000
Y44 Agents primarily affecting blood constituents
0.678 0.322 0.000
N99-N99 Other disorders of the genitourinary system
0.675 0.325 0.000
N80.6 Endometriosis in cutaneous scar
0.675 0.325 0.000
N80.5 Endometriosis of intestine
0.675 0.325 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.675 0.325 0.000
N80.2 Endometriosis of Fallopian tube
0.675 0.325 0.000
V10-V19 Pedal cyclist injured in transport accident
0.674 0.326 0.000
J39 Other diseases of upper respiratory tract
0.672 0.328 0.000
M79.79 Fibromyalgia (Site unspecified)
0.671 0.328 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.330 0.000
M54.4 Lumbago with sciatica
0.670 0.330 0.000
N03.9 Unspecified
0.669 0.331 0.000
N10-N16 Renal tubulo-interstitial diseases
0.669 0.331 0.000
N70.0 Acute salpingitis and oophoritis
0.668 0.332 0.000
G47.9 Sleep disorder, unspecified
0.667 0.333 0.000
S70 Superficial injury of hip and thigh
0.665 0.335 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.665 0.335 0.000
A41.9 Septicaemia, unspecified
0.664 0.336 0.000
N87 Dysplasia of cervix uteri
0.663 0.337 0.000
M53 Other dorsopathies, not elsewhere classified
0.662 0.338 0.000
M54.59 Low back pain (Site unspecified)
0.661 0.339 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.660 0.340 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.660 0.340 0.000
Q35-Q37 Cleft lip and cleft palate
0.660 0.340 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.660 0.340 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.660 0.340 0.000
S20-S29 Injuries to the thorax
0.659 0.340 0.000
J30.4 Allergic rhinitis, unspecified
0.659 0.341 0.000
M10 Gout
0.659 0.341 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.658 0.341 0.000
J46 Status asthmaticus
0.657 0.342 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.657 0.343 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.655 0.345 0.000
J09-J18 Influenza and pneumonia
0.654 0.346 0.000
B25-B34 Other viral diseases
0.653 0.347 0.000
A04.8 Other specified bacterial intestinal infections
0.653 0.347 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.653 0.347 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.651 0.349 0.000
Chapter VII Diseases of the eye and adnexa
0.650 0.350 0.000
G30-G32 Other degenerative diseases of the nervous system
0.649 0.351 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.649 0.351 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.648 0.352 0.000
Y59 Other and unspecified vaccines and biological substances
0.647 0.353 0.000
Y58 Bacterial vaccines
0.647 0.353 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.647 0.353 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.647 0.353 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.647 0.353 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.647 0.353 0.000
Y48 Anaesthetics and therapeutic gases
0.647 0.353 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.647 0.353 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.647 0.353 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.647 0.353 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.647 0.353 0.000
B37 Candidiasis
0.646 0.354 0.000
Q61 Cystic kidney disease
0.646 0.354 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.646 0.354 0.000
T43.9 Psychotropic drug, unspecified
0.645 0.355 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.645 0.355 0.000
T43.6 Psychostimulants with abuse potential
0.645 0.355 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.645 0.355 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.645 0.355 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.645 0.355 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.645 0.355 0.000
M40-M43 Deforming dorsopathies
0.644 0.355 0.000
N48.8 Other specified disorders of penis
0.644 0.356 0.000
Y43 Primarily systemic agents
0.642 0.358 0.000
T93 Sequelae of injuries of lower limb
0.641 0.359 0.000
M80-M85 Disorders of bone density and structure
0.641 0.359 0.000
M50 Cervical disk disorders
0.638 0.362 0.000
A49 Bacterial infection of unspecified site
0.637 0.363 0.000
W00-W19 Falls
0.636 0.364 0.000
M24.9 Joint derangement, unspecified
0.636 0.364 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.636 0.364 0.000
M24.7 Protrusio acetabuli
0.636 0.364 0.000
M24.6 Ankylosis of joint
0.636 0.364 0.000
M24.5 Contracture of joint
0.636 0.364 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.636 0.364 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.636 0.364 0.000
M24.2 Disorder of ligament
0.636 0.364 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.636 0.364 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.636 0.364 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.636 0.364 0.000
G41 Status epilepticus
0.636 0.364 0.000
T92 Sequelae of injuries of upper limb
0.636 0.364 0.000
J60-J70 Lung diseases due to external agents
0.635 0.365 0.000
Y40.3 Macrolides
0.635 0.365 0.000
G58 Other mononeuropathies
0.635 0.365 0.000
G54 Nerve root and plexus disorders
0.635 0.365 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.635 0.365 0.000
G52 Disorders of other cranial nerves
0.635 0.365 0.000
M54.8 Other dorsalgia
0.633 0.367 0.000
M54.6 Pain in thoracic spine
0.633 0.367 0.000
M54.0 Panniculitis affecting regions of neck and back
0.633 0.367 0.000
N20 Calculus of kidney and ureter
0.633 0.367 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.633 0.367 0.000
M23.4 Loose body in knee
0.632 0.368 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.632 0.368 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.632 0.368 0.000
M54.56 Low back pain (Lumbar region)
0.630 0.370 0.000
B91 Sequelae of poliomyelitis
0.630 0.370 0.000
N02 Recurrent and persistent haematuria
0.630 0.370 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.629 0.371 0.000
A48 Other bacterial diseases, not elsewhere classified
0.628 0.372 0.000
A44 Bartonellosis
0.628 0.372 0.000
A43 Nocardiosis
0.628 0.372 0.000
A42 Actinomycosis
0.628 0.372 0.000
A40 Streptococcal septicaemia
0.628 0.372 0.000
A39 Meningococcal infection
0.628 0.372 0.000
A37 Whooping cough
0.628 0.372 0.000
A36 Diphtheria
0.628 0.372 0.000
A32 Listeriosis
0.628 0.372 0.000
A31 Infection due to other mycobacteria
0.628 0.372 0.000
A30 Leprosy [Hansen's disease]
0.628 0.372 0.000
A46 Erysipelas
0.628 0.372 0.000
A38 Scarlet fever
0.628 0.372 0.000
A35 Other tetanus
0.628 0.372 0.000
A34 Obstetrical tetanus
0.628 0.372 0.000
A33 Tetanus neonatorum
0.628 0.372 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.628 0.372 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.628 0.372 0.000
J95-J99 Other diseases of the respiratory system
0.627 0.373 0.000
N95 Menopausal and other perimenopausal disorders
0.627 0.373 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.626 0.373 0.000
M77.4 Metatarsalgia
0.626 0.374 0.000
J30.3 Other allergic rhinitis
0.625 0.375 0.000
J30.2 Other seasonal allergic rhinitis
0.625 0.375 0.000
J30.0 Vasomotor rhinitis
0.625 0.375 0.000
M31.6 Other giant cell arteritis
0.625 0.375 0.000
W44 Foreign body entering into or through eye or natural orifice
0.625 0.375 0.000
M49 Spondylopathies in diseases classified elsewhere
0.625 0.375 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.624 0.376 0.000
N42.9 Disorder of prostate, unspecified
0.624 0.376 0.000
Y57 Other and unspecified drugs and medicaments
0.623 0.377 0.000
M72 Fibroblastic disorders
0.622 0.378 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.622 0.378 0.000
G43.9 Migraine, unspecified
0.622 0.378 0.000
M23.9 Internal derangement of knee, unspecified
0.621 0.378 0.000
M23.5 Chronic instability of knee
0.621 0.378 0.000
M23.1 Discoid meniscus (congenital)
0.621 0.378 0.000
M23.0 Cystic meniscus
0.621 0.378 0.000
Y40.0 Penicillins
0.621 0.379 0.000
B02.9 Zoster without complication
0.621 0.379 0.000
Y85 Sequelae of transport accidents
0.621 0.379 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.621 0.379 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.620 0.380 0.000
N06 Isolated proteinuria with specified morphological lesion
0.620 0.380 0.000
N05 Unspecified nephritic syndrome
0.620 0.380 0.000
N01 Rapidly progressive nephritic syndrome
0.620 0.380 0.000
N00 Acute nephritic syndrome
0.620 0.380 0.000
N04 Nephrotic syndrome
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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