TreeWAS – Variant ID: rs7726839

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.249	0.751	0.000
K44 Diaphragmatic hernia	0.105	0.895	0.000
M06.9 Rheumatoid arthritis, unspecified	0.079	0.921	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.076	0.924	0.000
M06 Other rheumatoid arthritis	0.075	0.925	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.075	0.925	0.000
K44.1 Diaphragmatic hernia with gangrene	0.074	0.926	0.000
M06.0 Seronegative rheumatoid arthritis	0.072	0.928	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.071	0.929	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.070	0.930	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.069	0.931	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.069	0.931	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.068	0.932	0.000
M06.3 Rheumatoid nodule	0.065	0.935	0.000
M06.4 Inflammatory polyarthropathy	0.065	0.935	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.062	0.938	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.057	0.943	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.057	0.943	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.055	0.945	0.000
M06.34 Rheumatoid nodule (Hand)	0.054	0.946	0.000
M06.8 Other specified rheumatoid arthritis	0.054	0.946	0.000
M06.2 Rheumatoid bursitis	0.054	0.946	0.000
M06.1 Adult-onset Still's disease	0.054	0.946	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.054	0.946	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.054	0.946	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.052	0.948	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.052	0.948	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.052	0.948	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.052	0.948	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.052	0.948	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.052	0.948	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.052	0.948	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.052	0.948	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.051	0.949	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.046	0.953	0.000
M06.38 Rheumatoid nodule (Other)	0.046	0.953	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.046	0.953	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.046	0.953	0.000
M06.33 Rheumatoid nodule (Forearm)	0.046	0.953	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.046	0.953	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.046	0.953	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.046	0.953	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.046	0.953	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.046	0.953	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.046	0.953	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.046	0.953	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.046	0.953	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.046	0.953	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.046	0.954	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.041	0.959	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.040	0.960	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.039	0.961	0.000
M06.18 Adult-onset Still's disease (Other)	0.039	0.961	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.039	0.961	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.039	0.961	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.039	0.961	0.000
M06.14 Adult-onset Still's disease (Hand)	0.039	0.961	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.039	0.961	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.039	0.961	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.039	0.961	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.039	0.961	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.039	0.961	0.000
M06.28 Rheumatoid bursitis (Other)	0.039	0.961	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.039	0.961	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.039	0.961	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.039	0.961	0.000
M06.24 Rheumatoid bursitis (Hand)	0.039	0.961	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.039	0.961	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.039	0.961	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.039	0.961	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.039	0.961	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.039	0.961	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.039	0.961	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.039	0.961	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.039	0.961	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.039	0.961	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.039	0.961	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.039	0.961	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.039	0.961	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.039	0.961	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.039	0.961	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.038	0.961	0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.034	0.966	0.000
Q60.0 Renal agenesis, unilateral	0.017	0.983	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.016	0.984	0.000
Q60-Q64 Congenital malformations of the urinary system	0.015	0.985	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.014	0.986	0.000
Q64 Other congenital malformations of urinary system	0.014	0.986	0.000
Q60.2 Renal agenesis, unspecified	0.013	0.986	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.013	0.987	0.000
Q62.5 Duplication of ureter	0.013	0.987	0.000
D13.1 Stomach	0.012	0.988	0.000
Q62.2 Congenital megaloureter	0.012	0.988	0.000
Q60.6 Potter's syndrome	0.012	0.988	0.000
Q60.5 Renal hypoplasia, unspecified	0.012	0.988	0.000
Q60.4 Renal hypoplasia, bilateral	0.012	0.988	0.000
Q60.3 Renal hypoplasia, unilateral	0.012	0.988	0.000
Q60.1 Renal agenesis, bilateral	0.012	0.988	0.000
Q62.8 Other congenital malformations of ureter	0.010	0.990	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.010	0.990	0.000
Q62.6 Malposition of ureter	0.010	0.990	0.000
Q62.4 Agenesis of ureter	0.010	0.990	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.010	0.990	0.000
Q62.1 Atresia and stenosis of ureter	0.010	0.990	0.000
Q62.0 Congenital hydronephrosis	0.010	0.990	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.010	0.990	0.000
Q64.8 Other specified congenital malformations of urinary system	0.010	0.990	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.010	0.990	0.000
Q64.6 Congenital diverticulum of bladder	0.010	0.990	0.000
Q64.5 Congenital absence of bladder and urethra	0.010	0.990	0.000
Q64.4 Malformation of urachus	0.010	0.990	0.000
Q64.2 Congenital posterior urethral valves	0.010	0.990	0.000
Q64.1 Exstrophy of urinary bladder	0.010	0.990	0.000
Q64.0 Epispadias	0.010	0.990	0.000
Q61 Cystic kidney disease	0.010	0.990	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.990	0.010
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.990	0.010
Q63 Other congenital malformations of kidney	0.009	0.991	0.000
K83.1 Obstruction of bile duct	0.000	0.991	0.009
K21 Gastro-oesophageal reflux disease	0.009	0.991	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.009	0.991	0.000
Q61.4 Renal dysplasia	0.008	0.991	0.000
Q80-Q89 Other congenital malformations	0.008	0.992	0.000
Q63.8 Other specified congenital malformations of kidney	0.008	0.992	0.000
Q61.9 Cystic kidney disease, unspecified	0.008	0.992	0.000
Q85 Phakomatoses, not elsewhere classified	0.008	0.992	0.000
M05-M14 Inflammatory polyarthropathies	0.008	0.992	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.008	0.992	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.008	0.992	0.000
Q61.5 Medullary cystic kidney	0.008	0.992	0.000
Q61.0 Congenital single renal cyst	0.008	0.992	0.000
C45.0 Mesothelioma of pleura	0.008	0.992	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
Q61.8 Other cystic kidney diseases	0.007	0.992	0.000
Q61.1 Polycystic kidney, infantile type	0.007	0.992	0.000
D13.0 Oesophagus	0.008	0.992	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.007	0.993	0.000
D13.4 Liver	0.007	0.993	0.000
S83.2 Tear of meniscus, current	0.000	0.993	0.007
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.007	0.993	0.000
Q63.2 Ectopic kidney	0.007	0.993	0.000
Q89 Other congenital malformations, not elsewhere classified	0.007	0.993	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.007	0.993	0.000
Q63.3 Hyperplastic and giant kidney	0.007	0.993	0.000
Q38.7 Pharyngeal pouch	0.007	0.993	0.000
F31 Bipolar affective disorder	0.000	0.993	0.007
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.993	0.007
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.993	0.007
S82.60 Fracture of lateral malleolus (closed)	0.000	0.993	0.007
M05 Seropositive rheumatoid arthritis	0.007	0.993	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.007	0.993	0.000
Q85.9 Phakomatosis, unspecified	0.006	0.993	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.993	0.006
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.006	0.994	0.000
Q35-Q37 Cleft lip and cleft palate	0.006	0.994	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.006	0.994	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.994	0.006
Q38.1 Ankyloglossia	0.006	0.994	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.006	0.994	0.000
Q84 Other congenital malformations of integument	0.006	0.994	0.000
Q81 Epidermolysis bullosa	0.006	0.994	0.000
Q80 Congenital ichthyosis	0.006	0.994	0.000
Q45 Other congenital malformations of digestive system	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
Q83 Congenital malformations of breast	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q61.3 Polycystic kidney, unspecified	0.006	0.994	0.000
Q89.2 Congenital malformations of other endocrine glands	0.006	0.994	0.000
M12 Other specific arthropathies	0.006	0.994	0.000
Q21.1 Atrial septal defect	0.006	0.994	0.000
D13.9 Ill-defined sites within the digestive system	0.006	0.994	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.006	0.994	0.000
M08 Juvenile arthritis	0.006	0.994	0.000
Q85.1 Tuberous sclerosis	0.006	0.994	0.000
D13.7 Endocrine pancreas	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q87.4 Marfan's syndrome	0.006	0.994	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.994	0.006
F31.7 Bipolar affective disorder, currently in remission	0.000	0.994	0.006
M14 Arthropathies in other diseases classified elsewhere	0.006	0.994	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.994	0.000
D13.6 Pancreas	0.005	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.005	0.994	0.000
Q38.8 Other congenital malformations of pharynx	0.005	0.994	0.000
Q38.6 Other congenital malformations of mouth	0.005	0.994	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.005	0.994	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.005	0.994	0.000
Q38.3 Other congenital malformations of tongue	0.005	0.994	0.000
Q38.2 Macroglossia	0.005	0.994	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.005	0.994	0.000
D13.3 Other and unspecified parts of small intestine	0.005	0.994	0.000
S89.9 Unspecified injury of lower leg	0.000	0.994	0.006
Q85.8 Other phakomatoses, not elsewhere classified	0.005	0.995	0.000
M10 Gout	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
D13.5 Extrahepatic bile ducts	0.005	0.995	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.005	0.995	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.995	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.005	0.995	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.005	0.995	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.005	0.995	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.005	0.995	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.005	0.995	0.000
Q89.9 Congenital malformation, unspecified	0.005	0.995	0.000
Q89.8 Other specified congenital malformations	0.005	0.995	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.005	0.995	0.000
Q89.4 Conjoined twins	0.005	0.995	0.000
Q89.3 Situs inversus	0.005	0.995	0.000
Q89.1 Congenital malformations of adrenal gland	0.005	0.995	0.000
Q89.0 Congenital malformations of spleen	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
Q63.0 Accessory kidney	0.005	0.995	0.000
D13.2 Duodenum	0.005	0.995	0.000
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
Q43 Other congenital malformations of intestine	0.005	0.995	0.000
Q51 Congenital malformations of uterus and cervix	0.005	0.995	0.000
Q66 Congenital deformities of feet	0.005	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.005	0.995	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.995	0.005
M12.2 Villonodular synovitis (pigmented)	0.005	0.995	0.000
M05.8 Other seropositive rheumatoid arthritis	0.005	0.995	0.000
M11 Other crystal arthropathies	0.005	0.995	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.005	0.995	0.000
M05.2 Rheumatoid vasculitis	0.005	0.995	0.000
M05.1 Rheumatoid lung disease	0.005	0.995	0.000
M05.0 Felty's syndrome	0.005	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.995	0.005
S81.0 Open wound of knee	0.000	0.995	0.005
M24.11 Other articular cartilage disorders (Shoulder region)	0.005	0.995	0.000
Q45.8 Other specified congenital malformations of digestive system	0.005	0.995	0.000
Q96 Turner's syndrome	0.005	0.995	0.000
Q39 Congenital malformations of oesophagus	0.005	0.995	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.995	0.005
Q83.8 Other congenital malformations of breast	0.005	0.995	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.005	0.995	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.005	0.995	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.005	0.995	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.005	0.995	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.005	0.995	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.005	0.995	0.000
Q90 Down's syndrome	0.005	0.995	0.000
Q34 Other congenital malformations of respiratory system	0.005	0.995	0.000
Q33 Congenital malformations of lung	0.005	0.995	0.000
Q32 Congenital malformations of trachea and bronchus	0.005	0.995	0.000
Q31 Congenital malformations of larynx	0.005	0.995	0.000
Q30 Congenital malformations of nose	0.005	0.995	0.000
Q37 Cleft palate with cleft lip	0.005	0.995	0.000
Q36 Cleft lip	0.005	0.995	0.000
Q35 Cleft palate	0.005	0.995	0.000
Q52 Other congenital malformations of female genitalia	0.005	0.995	0.000
Q51.3 Bicornate uterus	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.995	0.005
Q53 Undescended testicle	0.005	0.995	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.005	0.995	0.000
Q80.9 Congenital ichthyosis, unspecified	0.005	0.995	0.000
Q80.8 Other congenital ichthyosis	0.005	0.995	0.000
Q80.4 Harlequin foetus	0.005	0.995	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.005	0.995	0.000
Q80.2 Lamellar ichthyosis	0.005	0.995	0.000
Q80.1 X-linked ichthyosis	0.005	0.995	0.000
Q80.0 Ichthyosis vulgaris	0.005	0.995	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.005	0.995	0.000
Q81.8 Other epidermolysis bullosa	0.005	0.995	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.005	0.995	0.000
Q81.1 Epidermolysis bullosa letalis	0.005	0.995	0.000
Q81.0 Epidermolysis bullosa simplex	0.005	0.995	0.000
Q83.3 Accessory nipple	0.005	0.995	0.000
Q84.9 Congenital malformation of integument, unspecified	0.005	0.995	0.000
Q84.8 Other specified congenital malformations of integument	0.005	0.995	0.000
Q84.6 Other congenital malformations of nails	0.005	0.995	0.000
Q84.5 Enlarged and hypertrophic nails	0.005	0.995	0.000
Q84.4 Congenital leukonychia	0.005	0.995	0.000
Q84.3 Anonychia	0.005	0.995	0.000
Q84.2 Other congenital malformations of hair	0.005	0.995	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.005	0.995	0.000
Q84.0 Congenital alopecia	0.005	0.995	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.005	0.995	0.000
Q86.2 Dysmorphism due to warfarin	0.005	0.995	0.000
Q86.1 Foetal hydantoin syndrome	0.005	0.995	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.005	0.995	0.000
S81 Open wound of lower leg	0.000	0.995	0.005
Q45.9 Congenital malformation of digestive system, unspecified	0.005	0.995	0.000
Q45.2 Congenital pancreatic cyst	0.005	0.995	0.000
Q45.1 Annular pancreas	0.005	0.995	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.005	0.995	0.000
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.005	0.995	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.005	0.995	0.000
Q83.9 Congenital malformation of breast, unspecified	0.005	0.995	0.000
Q83.2 Absent nipple	0.005	0.995	0.000
Q83.0 Congenital absence of breast with absent nipple	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
M12.5 Traumatic arthropathy	0.004	0.995	0.000
M12.4 Intermittent hydrarthrosis	0.004	0.995	0.000
M12.1 Kaschin-Beck disease	0.004	0.995	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.004	0.995	0.000
Q66.0 Talipes equinovarus	0.005	0.995	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.995	0.005
M14.8 Arthropathies in other specified diseases classified elsewhere	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
M08.9 Juvenile arthritis, unspecified	0.004	0.995	0.000
M08.8 Other juvenile arthritis	0.004	0.995	0.000
M08.4 Pauciarticular juvenile arthritis	0.004	0.995	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.004	0.995	0.000
M08.2 Juvenile arthritis with systemic onset	0.004	0.995	0.000
M08.1 Juvenile ankylosing spondylitis	0.004	0.995	0.000
M08.0 Juvenile rheumatoid arthritis	0.004	0.995	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.004	0.995	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.004	0.995	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.004	0.995	0.000
M09.0 Juvenile arthritis in psoriasis	0.004	0.995	0.000
Q54 Hypospadias	0.005	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.995	0.000
Q21.2 Atrioventricular septal defect	0.004	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.004	0.995	0.000
Q66.8 Other congenital deformities of feet	0.005	0.995	0.000
C45 Mesothelioma	0.005	0.995	0.000
Q82 Other congenital malformations of skin	0.004	0.995	0.000
Q17 Other congenital malformations of ear	0.004	0.995	0.000
M24.23 Disorder of ligament (Forearm)	0.005	0.995	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.995	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.995	0.004
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
Q43.3 Congenital malformations of intestinal fixation	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.004	0.996	0.000
M14.4 Arthropathy in amyloidosis	0.004	0.996	0.000
M14.3 Lipoid dermatoarthritis	0.004	0.996	0.000
M14.2 Diabetic arthropathy	0.004	0.996	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.004	0.996	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.004	0.996	0.000
S82.6 Fracture of lateral malleolus	0.000	0.996	0.004
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.996	0.004
F31.8 Other bipolar affective disorders	0.000	0.996	0.004
M10.0 Idiopathic gout	0.004	0.996	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.004	0.996	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.004	0.996	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.004	0.996	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.004	0.996	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.004	0.996	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.004	0.996	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.004	0.996	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.004	0.996	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.004	0.996	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.004	0.996	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
M12.3 Palindromic rheumatism	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.004	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q40.1 Congenital hiatus hernia	0.004	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.004	0.996	0.000
Q83.1 Accessory breast	0.004	0.996	0.000
Q15 Other congenital malformations of eye	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q44.5 Other congenital malformations of bile ducts	0.004	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.004	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.004	0.996	0.000
M07 Psoriatic and enteropathic arthropathies	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
M10.4 Other secondary gout	0.004	0.996	0.000
M10.3 Gout due to impairment of renal function	0.004	0.996	0.000
M10.2 Drug-induced gout	0.004	0.996	0.000
M10.1 Lead-induced gout	0.004	0.996	0.000
Q44.7 Other congenital malformations of liver	0.004	0.996	0.000
Q44.4 Choledochal cyst	0.004	0.996	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.004	0.996	0.000
Q44.2 Atresia of bile ducts	0.004	0.996	0.000
Q44.1 Other congenital malformations of gallbladder	0.004	0.996	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M24 Other specific joint derangements	0.004	0.996	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.000	0.996	0.004
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.996	0.000
Q43.7 Persistent cloaca	0.004	0.996	0.000
Q43.6 Congenital fistula of rectum and anus	0.004	0.996	0.000
Q43.5 Ectopic anus	0.004	0.996	0.000
Q43.4 Duplication of intestine	0.004	0.996	0.000
Q43.2 Other congenital functional disorders of colon	0.004	0.996	0.000
Q43.1 Hirschsprung's disease	0.004	0.996	0.000
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.004	0.996	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.004	0.996	0.000
Q51.6 Embryonic cyst of cervix	0.004	0.996	0.000
Q51.5 Agenesis and aplasia of cervix	0.004	0.996	0.000
Q51.4 Unicornate uterus	0.004	0.996	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.004	0.996	0.000
Q51.0 Agenesis and aplasia of uterus	0.004	0.996	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.004	0.996	0.000
Q66.9 Congenital deformity of feet, unspecified	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
Q03 Congenital hydrocephalus	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M11.9 Crystal arthropathy, unspecified	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.996	0.000
Q01 Encephalocele	0.004	0.996	0.000
Q00 Anencephaly and similar malformations	0.004	0.996	0.000
Q02 Microcephaly	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
Q52.5 Fusion of labia	0.004	0.996	0.000
S01.1 Open wound of eyelid and periocular area	0.000	0.996	0.004
M24.2 Disorder of ligament	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.004	0.996	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.004	0.996	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.004	0.996	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.004	0.996	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.004	0.996	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.004	0.996	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.004	0.996	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.004	0.996	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
M10.00 Idiopathic gout (Multiple sites)	0.004	0.996	0.000
M11.1 Familial chondrocalcinosis	0.004	0.996	0.000
M11.0 Hydroxyapatite deposition disease	0.004	0.996	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.004	0.996	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.004	0.996	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.004	0.996	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.004	0.996	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.004	0.996	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.004	0.996	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.004	0.996	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.004	0.996	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
M05.09 Felty's syndrome (Site unspecified)	0.004	0.996	0.000
M05.08 Felty's syndrome (Other)	0.004	0.996	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.004	0.996	0.000
M05.06 Felty's syndrome (Lower leg)	0.004	0.996	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.004	0.996	0.000
M05.04 Felty's syndrome (Hand)	0.004	0.996	0.000
M05.03 Felty's syndrome (Forearm)	0.004	0.996	0.000
M05.02 Felty's syndrome (Upper arm)	0.004	0.996	0.000
M05.01 Felty's syndrome (Shoulder region)	0.004	0.996	0.000
M05.00 Felty's syndrome (Multiple sites)	0.004	0.996	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.004	0.996	0.000
M05.18 Rheumatoid lung disease (Other)	0.004	0.996	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.004	0.996	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.004	0.996	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.004	0.996	0.000
M05.14 Rheumatoid lung disease (Hand)	0.004	0.996	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.004	0.996	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.004	0.996	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.004	0.996	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.004	0.996	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.004	0.996	0.000
M05.28 Rheumatoid vasculitis (Other)	0.004	0.996	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.004	0.996	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.004	0.996	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.004	0.996	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.004	0.996	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.004	0.996	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.004	0.996	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations