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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7729458
log Bayes Factor = 5.89518
Chromosome 5   position 2,799,100  (GRCh37) Explore rs7729458 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.991 0.009 0.000
T93 Sequelae of injuries of lower limb
0.989 0.011 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.986 0.014 0.000
S60-S69 Injuries to the wrist and hand
0.985 0.015 0.000
M50-M54 Other dorsopathies
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.979 0.021 0.000
M54 Dorsalgia
0.978 0.022 0.000
M54.9 Dorsalgia, unspecified
0.975 0.025 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.972 0.028 0.000
I71 Aortic aneurysm and dissection
0.970 0.030 0.000
F30-F39 Mood [affective] disorders
0.967 0.033 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.957 0.043 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.955 0.045 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.954 0.046 0.000
F41 Other anxiety disorders
0.953 0.047 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.953 0.047 0.000
F33 Recurrent depressive disorder
0.952 0.048 0.000
M45-M49 Spondylopathies
0.949 0.051 0.000
S90-S99 Injuries to the ankle and foot
0.948 0.052 0.000
F41.2 Mixed anxiety and depressive disorder
0.947 0.053 0.000
I60-I69 Cerebrovascular diseases
0.946 0.054 0.000
M48 Other spondylopathies
0.944 0.056 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.943 0.057 0.000
M48.0 Spinal stenosis
0.942 0.058 0.000
M48.06 Spinal stenosis (Lumbar region)
0.938 0.062 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.937 0.063 0.000
Y45.0 Opioids and related analgesics
0.936 0.064 0.000
S69 Other and unspecified injuries of wrist and hand
0.934 0.066 0.000
I78 Diseases of capillaries
0.934 0.066 0.000
F43 Reaction to severe stress, and adjustment disorders
0.931 0.069 0.000
S62 Fracture at wrist and hand level
0.931 0.069 0.000
T39.0 Salicylates
0.930 0.070 0.000
M86-M90 Other osteopathies
0.929 0.070 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.926 0.074 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.926 0.074 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.921 0.079 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.921 0.079 0.000
X60-X84 Intentional self-harm
0.919 0.081 0.000
I61 Intracerebral haemorrhage
0.914 0.086 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.912 0.088 0.000
I60 Subarachnoid haemorrhage
0.909 0.091 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.908 0.092 0.000
M54.2 Cervicalgia
0.906 0.094 0.000
S50-S59 Injuries to the elbow and forearm
0.904 0.096 0.000
F60-F69 Disorders of adult personality and behaviour
0.904 0.096 0.000
F43.1 Posttraumatic stress disorder
0.901 0.099 0.000
I78.1 Naevus, nonneoplastic
0.900 0.100 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.888 0.112 0.000
Y95 Nosocomial condition
0.888 0.112 0.000
M54.5 Low back pain
0.885 0.115 0.000
Y42.7 Androgens and anabolic congeners
0.885 0.115 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.882 0.118 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.880 0.120 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.880 0.120 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.879 0.121 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.879 0.121 0.000
Chapter X Diseases of the respiratory system
0.871 0.129 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.868 0.132 0.000
T51 Toxic effect of alcohol
0.865 0.135 0.000
M54.22 Cervicalgia (Cervical region)
0.863 0.137 0.000
S62.3 Fracture of other metacarpal bone
0.861 0.139 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.857 0.143 0.000
S69.9 Unspecified injury of wrist and hand
0.856 0.144 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.855 0.145 0.000
J95-J99 Other diseases of the respiratory system
0.851 0.149 0.000
M87 Osteonecrosis
0.847 0.153 0.000
T93.1 Sequelae of fracture of femur
0.843 0.157 0.000
T00-T07 Injuries involving multiple body regions
0.840 0.160 0.000
T39.1 4-Aminophenol derivatives
0.839 0.161 0.000
I65.2 Occlusion and stenosis of carotid artery
0.837 0.163 0.000
F60 Specific personality disorders
0.837 0.163 0.000
Q80-Q89 Other congenital malformations
0.830 0.170 0.000
S70-S79 Injuries to the hip and thigh
0.829 0.171 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.827 0.173 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.826 0.174 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.820 0.180 0.000
Y57 Other and unspecified drugs and medicaments
0.819 0.181 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.817 0.183 0.000
S20-S29 Injuries to the thorax
0.817 0.183 0.000
I72 Other aneurysm
0.816 0.184 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.816 0.184 0.000
F30 Manic episode
0.815 0.185 0.000
V40-V49 Car occupant injured in transport accident
0.814 0.186 0.000
M91-M94 Chondropathies
0.814 0.186 0.000
S60 Superficial injury of wrist and hand
0.814 0.186 0.000
M54.56 Low back pain (Lumbar region)
0.814 0.186 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.813 0.187 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.813 0.187 0.000
S92 Fracture of foot, except ankle
0.812 0.188 0.000
T51.9 Alcohol, unspecified
0.812 0.188 0.000
I05-I09 Chronic rheumatic heart diseases
0.811 0.189 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.810 0.190 0.000
I99 Other and unspecified disorders of circulatory system
0.808 0.192 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.808 0.192 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.808 0.192 0.000
F44 Dissociative [conversion] disorders
0.807 0.193 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.806 0.194 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.804 0.196 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.803 0.197 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.803 0.197 0.000
S69.7 Multiple injuries of wrist and hand
0.802 0.198 0.000
V80-V89 Other land transport accidents
0.800 0.200 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.798 0.202 0.000
T90 Sequelae of injuries of head
0.795 0.205 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.793 0.207 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.791 0.209 0.000
V01-V09 Pedestrian injured in transport accident
0.791 0.209 0.000
W50-W64 Exposure to animate mechanical forces
0.789 0.211 0.000
X50-X57 Overexertion, travel and privation
0.789 0.211 0.000
T92 Sequelae of injuries of upper limb
0.789 0.211 0.000
M89 Other disorders of bone
0.788 0.212 0.000
S90 Superficial injury of ankle and foot
0.784 0.215 0.000
F41.8 Other specified anxiety disorders
0.784 0.216 0.000
F99-F99 Unspecified mental disorder
0.784 0.216 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.784 0.216 0.000
S70 Superficial injury of hip and thigh
0.783 0.217 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.782 0.218 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.781 0.219 0.000
T36 Poisoning by systemic antibiotics
0.781 0.219 0.000
S62.7 Multiple fractures of fingers
0.780 0.220 0.000
M48.02 Spinal stenosis (Cervical region)
0.779 0.221 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.779 0.221 0.000
F48 Other neurotic disorders
0.779 0.221 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.778 0.222 0.000
Y48 Anaesthetics and therapeutic gases
0.777 0.223 0.000
S51 Open wound of forearm
0.777 0.223 0.000
J95.8 Other postprocedural respiratory disorders
0.774 0.226 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.773 0.227 0.000
V98-V99 Other and unspecified transport accidents
0.773 0.227 0.000
J60-J70 Lung diseases due to external agents
0.772 0.228 0.000
T14 Injury of unspecified body region
0.772 0.228 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.772 0.228 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.771 0.228 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.770 0.230 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.767 0.233 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.767 0.233 0.000
T93.2 Sequelae of other fractures of lower limb
0.767 0.233 0.000
S64 Injury of nerves at wrist and hand level
0.766 0.234 0.000
M87.9 Osteonecrosis, unspecified
0.766 0.234 0.000
T50.4 Drugs affecting uric acid metabolism
0.764 0.235 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.763 0.237 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.762 0.238 0.000
Q60-Q64 Congenital malformations of the urinary system
0.761 0.239 0.000
T79-T79 Certain early complications of trauma
0.759 0.241 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.758 0.242 0.000
W75-W84 Other accidental threats to breathing
0.754 0.245 0.000
Y10-Y34 Event of undetermined intent
0.754 0.246 0.000
M00-M03 Infectious arthropathies
0.754 0.246 0.000
F80-F89 Disorders of psychological development
0.753 0.247 0.000
T54 Toxic effect of corrosive substances
0.751 0.249 0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)
0.751 0.249 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.749 0.251 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.747 0.253 0.000
M54.8 Other dorsalgia
0.746 0.254 0.000
T65 Toxic effect of other and unspecified substances
0.745 0.255 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
J40-J47 Chronic lower respiratory diseases
0.743 0.257 0.000
T58 Toxic effect of carbon monoxide
0.742 0.258 0.000
T93.0 Sequelae of open wound of lower limb
0.742 0.258 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.742 0.258 0.000
I71.0 Dissection of aorta [any part]
0.740 0.260 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.739 0.261 0.000
F34 Persistent mood [affective] disorders
0.737 0.263 0.000
J98 Other respiratory disorders
0.737 0.263 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.733 0.267 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.733 0.267 0.000
I61.8 Other intracerebral haemorrhage
0.733 0.267 0.000
T01 Open wounds involving multiple body regions
0.732 0.268 0.000
J44 Other chronic obstructive pulmonary disease
0.731 0.269 0.000
M86 Osteomyelitis
0.731 0.269 0.000
X78 Intentional self-harm by sharp object
0.731 0.269 0.000
Y57.9 Drug or medicament, unspecified
0.730 0.270 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.729 0.271 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.728 0.272 0.000
F39 Unspecified mood [affective] disorder
0.728 0.272 0.000
Y00-Y09 Assault
0.728 0.272 0.000
M89.8 Other specified disorders of bone
0.727 0.273 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.727 0.273 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.727 0.273 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.723 0.277 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.722 0.278 0.000
X10-X19 Contact with heat and hot substances
0.720 0.280 0.000
M48.09 Spinal stenosis (Site unspecified)
0.719 0.281 0.000
M54.59 Low back pain (Site unspecified)
0.718 0.282 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
M05-M14 Inflammatory polyarthropathies
0.715 0.285 0.000
T95 Sequelae of burns, corrosions and frostbite
0.714 0.286 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.714 0.286 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.286 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.713 0.287 0.000
V10-V19 Pedal cyclist injured in transport accident
0.712 0.288 0.000
F60.9 Personality disorder, unspecified
0.712 0.288 0.000
Y54.3 Benzothiadiazine derivatives
0.711 0.289 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
Y59 Other and unspecified vaccines and biological substances
0.710 0.290 0.000
Y58 Bacterial vaccines
0.710 0.290 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.710 0.290 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.710 0.290 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.710 0.290 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.710 0.290 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.709 0.291 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.709 0.291 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.709 0.291 0.000
Y45.8 Other analgesics and antipyretics
0.709 0.291 0.000
F70-F79 Mental retardation
0.708 0.292 0.000
S91 Open wound of ankle and foot
0.707 0.293 0.000
I00-I02 Acute rheumatic fever
0.707 0.293 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.706 0.294 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.705 0.295 0.000
I60.8 Other subarachnoid haemorrhage
0.705 0.295 0.000
M40-M43 Deforming dorsopathies
0.703 0.297 0.000
M54.0 Panniculitis affecting regions of neck and back
0.701 0.299 0.000
T98 Sequelae of other and unspecified effects of external causes
0.700 0.299 0.000
Q50-Q56 Congenital malformations of genital organs
0.700 0.300 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.699 0.300 0.000
T90.9 Sequelae of unspecified injury of head
0.699 0.301 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.699 0.301 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.699 0.301 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.699 0.301 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.699 0.301 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.698 0.301 0.000
S60.8 Other superficial injuries of wrist and hand
0.698 0.302 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.698 0.302 0.000
T39.4 Antirheumatics, not elsewhere classified
0.696 0.303 0.000
T39.2 Pyrazolone derivatives
0.696 0.303 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.695 0.304 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.695 0.304 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.695 0.304 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.695 0.304 0.000
Q23 Congenital malformations of aortic and mitral valves
0.695 0.305 0.000
S50 Superficial injury of forearm
0.695 0.305 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.695 0.305 0.000
M65-M68 Disorders of synovium and tendon
0.694 0.305 0.000
F43.9 Reaction to severe stress, unspecified
0.694 0.306 0.000
F38 Other mood [affective] disorders
0.693 0.306 0.000
F60.7 Dependent personality disorder
0.693 0.307 0.000
S69.8 Other specified injuries of wrist and hand
0.693 0.307 0.000
M53 Other dorsopathies, not elsewhere classified
0.692 0.307 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.691 0.309 0.000
I78.8 Other diseases of capillaries
0.691 0.309 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.690 0.310 0.000
Y45.5 4-Aminophenol derivatives
0.689 0.311 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.688 0.312 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.688 0.312 0.000
S20 Superficial injury of thorax
0.688 0.312 0.000
M54.4 Lumbago with sciatica
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
M92 Other juvenile osteochondrosis
0.686 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.686 0.313 0.000
Q35-Q37 Cleft lip and cleft palate
0.686 0.313 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.686 0.313 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.685 0.315 0.000
Y41.5 Antiviral drugs
0.685 0.315 0.000
T56 Toxic effect of metals
0.685 0.315 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.684 0.316 0.000
Y45.4 Antirheumatics
0.684 0.316 0.000
M54.6 Pain in thoracic spine
0.684 0.316 0.000
T50.8 Diagnostic agents
0.684 0.316 0.000
T50.7 Analeptics and opioid receptor antagonists
0.684 0.316 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.684 0.316 0.000
T50.5 Appetite depressants
0.684 0.316 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.684 0.316 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.684 0.316 0.000
T50.1 Loop [high-ceiling] diuretics
0.684 0.316 0.000
T50.0 Mineralocorticoids and their antagonists
0.684 0.316 0.000
S65 Injury of blood vessels at wrist and hand level
0.684 0.316 0.000
F41.3 Other mixed anxiety disorders
0.683 0.316 0.000
F33.8 Other recurrent depressive disorders
0.683 0.317 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.683 0.317 0.000
T94.1 Sequelae of injuries, not specified by body region
0.683 0.317 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.319 0.000
I27 Other pulmonary heart diseases
0.680 0.320 0.000
S98 Traumatic amputation of ankle and foot
0.679 0.320 0.000
S97 Crushing injury of ankle and foot
0.679 0.320 0.000
S95 Injury of blood vessels at ankle and foot level
0.679 0.320 0.000
S94 Injury of nerves at ankle and foot level
0.679 0.320 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.679 0.321 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.678 0.321 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.678 0.321 0.000
S56 Injury of muscle and tendon at forearm level
0.678 0.322 0.000
S92.5 Fracture of other toe
0.678 0.322 0.000
S54 Injury of nerves at forearm level
0.677 0.323 0.000
M48.9 Spondylopathy, unspecified
0.677 0.323 0.000
M48.8 Other specified spondylopathies
0.677 0.323 0.000
M48.4 Fatigue fracture of vertebra
0.677 0.323 0.000
M48.3 Traumatic spondylopathy
0.677 0.323 0.000
M48.2 Kissing spine
0.677 0.323 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.677 0.323 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.677 0.323 0.000
Q89 Other congenital malformations, not elsewhere classified
0.676 0.324 0.000
S29 Other and unspecified injuries of thorax
0.676 0.324 0.000
T62 Toxic effect of other noxious substances eaten as food
0.676 0.324 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.676 0.324 0.000
T60 Toxic effect of pesticides
0.676 0.324 0.000
T57 Toxic effect of other inorganic substances
0.676 0.324 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.676 0.324 0.000
T52 Toxic effect of organic solvents
0.676 0.324 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.676 0.324 0.000
T55 Toxic effect of soaps and detergents
0.676 0.324 0.000
I72.3 Aneurysm of iliac artery
0.676 0.324 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.676 0.324 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.676 0.324 0.000
M48.04 Spinal stenosis (Thoracic region)
0.676 0.324 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.676 0.324 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.676 0.324 0.000
I74 Arterial embolism and thrombosis
0.675 0.325 0.000
M60-M63 Disorders of muscles
0.673 0.327 0.000
M88 Paget's disease of bone [osteitis deformans]
0.673 0.327 0.000
S62.70 Multiple fractures of fingers (closed)
0.673 0.327 0.000
M05 Seropositive rheumatoid arthritis
0.673 0.327 0.000
M87.2 Osteonecrosis due to previous trauma
0.672 0.328 0.000
T43.9 Psychotropic drug, unspecified
0.672 0.328 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
T43.6 Psychostimulants with abuse potential
0.672 0.328 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.672 0.328 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.672 0.328 0.000
F30.9 Manic episode, unspecified
0.672 0.328 0.000
M54.50 Low back pain (Multiple sites in spine)
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.670 0.330 0.000
Q82 Other congenital malformations of skin
0.670 0.330 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.670 0.330 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.670 0.330 0.000
I78.9 Disease of capillaries, unspecified
0.669 0.330 0.000
T63 Toxic effect of contact with venomous animals
0.669 0.331 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.668 0.332 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.668 0.332 0.000
M70-M79 Other soft tissue disorders
0.668 0.332 0.000
S99 Other and unspecified injuries of ankle and foot
0.668 0.332 0.000
F43.8 Other reactions to severe stress
0.668 0.332 0.000
S62.1 Fracture of other carpal bone(s)
0.667 0.333 0.000
Y45.2 Propionic acid derivatives
0.666 0.334 0.000
S92.0 Fracture of calcaneus
0.665 0.335 0.000
I72.1 Aneurysm of artery of upper extremity
0.665 0.335 0.000
I05 Rheumatic mitral valve diseases
0.665 0.335 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.664 0.336 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.664 0.336 0.000
Y98 Lifestyle-related condition
0.664 0.336 0.000
Y97 Environmental-pollution-related condition
0.664 0.336 0.000
Y96 Work-related condition
0.664 0.336 0.000
Q00-Q07 Congenital malformations of the nervous system
0.663 0.337 0.000
F69 Unspecified disorder of adult personality and behaviour
0.662 0.338 0.000
Y54.5 Other diuretics
0.662 0.338 0.000
J98.8 Other specified respiratory disorders
0.661 0.339 0.000
Y42.9 Other and unspecified hormone antagonists
0.660 0.339 0.000
Y42.4 Oral contraceptives
0.660 0.339 0.000
Y42.2 Antithyroid drugs
0.660 0.339 0.000
Y42.1 Thyroid hormones and substitutes
0.660 0.339 0.000
T14.0 Superficial injury of unspecified body region
0.660 0.340 0.000
X84 Intentional self-harm by unspecified means
0.659 0.341 0.000
X83 Intentional self-harm by other specified means
0.659 0.341 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.659 0.341 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.659 0.341 0.000
X80 Intentional self-harm by jumping from a high place
0.659 0.341 0.000
X79 Intentional self-harm by blunt object
0.659 0.341 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.659 0.341 0.000
X76 Intentional self-harm by smoke, fire and flames
0.659 0.341 0.000
X75 Intentional self-harm by explosive material
0.659 0.341 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.659 0.341 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.659 0.341 0.000
X72 Intentional self-harm by handgun discharge
0.659 0.341 0.000
X71 Intentional self-harm by drowning and submersion
0.659 0.341 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.659 0.341 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.659 0.341 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.659 0.341 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.659 0.341 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.659 0.341 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.659 0.341 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.658 0.342 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.658 0.342 0.000
S62.4 Multiple fractures of metacarpal bones
0.658 0.342 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.656 0.344 0.000
I06 Rheumatic aortic valve diseases
0.656 0.344 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.656 0.344 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.656 0.344 0.000
F45 Somatoform disorders
0.655 0.345 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.655 0.345 0.000
J40 Bronchitis, not specified as acute or chronic
0.655 0.345 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.654 0.346 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.654 0.346 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.654 0.346 0.000
T46.7 Peripheral vasodilators
0.654 0.346 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.654 0.346 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.654 0.346 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.654 0.346 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.654 0.346 0.000
M49 Spondylopathies in diseases classified elsewhere
0.654 0.346 0.000
T09 Other injuries of spine and trunk, level unspecified
0.653 0.347 0.000
F60.6 Anxious [avoidant] personality disorder
0.652 0.348 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.651 0.348 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.651 0.348 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.651 0.348 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.651 0.348 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.650 0.350 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.650 0.350 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.650 0.350 0.000
M54.27 Cervicalgia-Lumbosacral
0.650 0.350 0.000
M54.26 Cervicalgia-Lumbar
0.650 0.350 0.000
M54.25 Cervicalgia-Thoracolumbar
0.650 0.350 0.000
M54.24 Cervicalgia-Thoracic
0.650 0.350 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.650 0.350 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.650 0.350 0.000
M54.20 Cervicalgia-Mult site
0.650 0.350 0.000
S59 Other and unspecified injuries of forearm
0.648 0.352 0.000
S58 Traumatic amputation of forearm
0.648 0.352 0.000
S57 Crushing injury of forearm
0.648 0.352 0.000
S55 Injury of blood vessels at forearm level
0.648 0.352 0.000
F68 Other disorders of adult personality and behaviour
0.648 0.352 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.648 0.352 0.000
F65 Disorders of sexual preference
0.648 0.352 0.000
F63 Habit and impulse disorders
0.648 0.352 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.648 0.352 0.000
F61 Mixed and other personality disorders
0.648 0.352 0.000
J98.2 Interstitial emphysema
0.646 0.354 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.645 0.355 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.645 0.355 0.000
S52 Fracture of forearm
0.645 0.355 0.000
F60.3 Emotionally unstable personality disorder
0.645 0.355 0.000
S61 Open wound of wrist and hand
0.645 0.355 0.000
Y48.4 Anaesthetic, unspecified
0.644 0.356 0.000
Q18 Other congenital malformations of face and neck
0.643 0.357 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.643 0.357 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.642 0.358 0.000
V04 Pedestrian injured in collision with heavy transport vehicle or bus
0.642 0.358 0.000
F33.9 Recurrent depressive disorder, unspecified
0.641 0.359 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.641 0.359 0.000
F30.0 Hypomania
0.641 0.359 0.000
W20-W49 Exposure to inanimate mechanical forces
0.640 0.360 0.000
Y54.8 Agents affecting uric acid metabolism
0.640 0.360 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.640 0.360 0.000
T46.1 Calcium-channel blockers
0.639 0.361 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.639 0.361 0.000
F64 Gender identity disorders
0.639 0.361 0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level
0.638 0.362 0.000
T14.1 Open wound of unspecified body region
0.638 0.362 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.637 0.363 0.000
F43.0 Acute stress reaction
0.636 0.364 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.636 0.364 0.000
I72.0 Aneurysm of carotid artery
0.635 0.365 0.000
S92.4 Fracture of great toe
0.635 0.365 0.000
M54.54 Low back pain-Thoracic
0.635 0.365 0.000
M54.53 Low back pain-Cervicothoracic
0.635 0.365 0.000
M54.52 Low back pain-Cervical
0.635 0.365 0.000
M54.51 Low back pain-Occipit-atl-axl
0.635 0.365 0.000
M89.88 Other specified disorders of bone (Other)
0.633 0.367 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.633 0.367 0.000
X51 Travel and motion
0.632 0.368 0.000
F99 Mental disorder, not otherwise specified
0.632 0.368 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.632 0.368 0.000
T20 Burn and corrosion of head and neck
0.632 0.368 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.631 0.369 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.631 0.369 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.631 0.369 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.631 0.369 0.000
I65.1 Occlusion and stenosis of basilar artery
0.631 0.369 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.631 0.369 0.000
Y41.4 Anthelminthics
0.631 0.369 0.000
Y41.3 Other antiprotozoal drugs
0.631 0.369 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.631 0.369 0.000
Y41.1 Antimycobacterial drugs
0.631 0.369 0.000
Y41.0 Sulphonamides
0.631 0.369 0.000
S62.2 Fracture of first metacarpal bone
0.631 0.369 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.631 0.369 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.630 0.370 0.000
F48.0 Neurasthenia
0.630 0.370 0.000
M45 Ankylosing spondylitis
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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