TreeWAS – Variant ID: rs77303550

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.001	0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.920	0.080
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.926	0.074
E78.6 Lipoprotein deficiency	0.000	0.940	0.060
E78.3 Hyperchylomicronaemia	0.000	0.942	0.057
E78.8 Other disorders of lipoprotein metabolism	0.000	0.951	0.049
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.048	0.952	0.000
C81 Hodgkin's disease	0.047	0.953	0.000
E78.4 Other hyperlipidaemia	0.000	0.954	0.046
C88 Malignant immunoproliferative diseases	0.045	0.955	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.045	0.955	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.044	0.956	0.000
C81.9 Hodgkin's disease, unspecified	0.043	0.957	0.000
C92 Myeloid leukaemia	0.043	0.957	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.042	0.958	0.000
C92.0 Acute myeloid leukaemia	0.040	0.960	0.000
C83.0 Small cell (diffuse)	0.040	0.960	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.039	0.961	0.000
C81.0 Lymphocytic predominance	0.039	0.961	0.000
C95 Leukaemia of unspecified cell type	0.038	0.961	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.038	0.962	0.000
C93 Monocytic leukaemia	0.037	0.963	0.000
C81.1 Nodular sclerosis	0.037	0.963	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.037	0.963	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.036	0.964	0.000
C83.7 Burkitt's tumour	0.036	0.964	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.036	0.964	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.036	0.964	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.035	0.965	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.035	0.965	0.000
C94 Other leukaemias of specified cell type	0.035	0.965	0.000
C86 Other specified types of T/NK-cell lymphoma	0.035	0.965	0.000
C92.7 Other myeloid leukaemia	0.034	0.965	0.000
C82.2 Large cell, follicular	0.034	0.965	0.000
C82.0 Small cleaved cell, follicular	0.034	0.966	0.000
C81.7 Other Hodgkin's disease	0.034	0.966	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.034	0.966	0.000
C81.3 Lymphocytic depletion	0.034	0.966	0.000
C81.2 Mixed cellularity	0.033	0.966	0.000
E78.1 Pure hyperglyceridaemia	0.001	0.967	0.033
C92.9 Myeloid leukaemia, unspecified	0.033	0.967	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.033	0.967	0.000
C88.7 Other malignant immunoproliferative diseases	0.033	0.967	0.000
C88.3 Immunoproliferative small intestinal disease	0.033	0.967	0.000
C88.2 Gamma heavy chain disease	0.033	0.967	0.000
C88.1 Alpha heavy chain disease	0.033	0.967	0.000
C82.6 Cutaneous follicle centre lymphoma	0.033	0.967	0.000
C82.5 Diffuse follicle centre lymphoma	0.033	0.967	0.000
C82.4 Follicular lymphoma grade IIIb	0.033	0.967	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.032	0.968	0.000
C83.6 Undifferentiated (diffuse)	0.032	0.968	0.000
C83.5 Lymphoblastic (diffuse)	0.032	0.968	0.000
C83.4 Immunoblastic (diffuse)	0.032	0.968	0.000
C83.2 Mixed small and large cell (diffuse)	0.032	0.968	0.000
C82.3 Follicular lymphoma grade IIIa	0.032	0.968	0.000
C95.9 Leukaemia, unspecified	0.031	0.968	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.031	0.969	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.031	0.969	0.000
C92.5 Acute myelomonocytic leukaemia	0.031	0.969	0.000
C92.3 Myeloid sarcoma	0.031	0.969	0.000
C92.2 Subacute myeloid leukaemia	0.031	0.969	0.000
C93.1 Chronic monocytic leukaemia	0.030	0.970	0.000
C84.5 Other and unspecified T-cell lymphomas	0.029	0.971	0.000
C84.0 Mycosis fungoides	0.029	0.971	0.000
C83.1 Small cleaved cell (diffuse)	0.028	0.972	0.000
C95.7 Other leukaemia of unspecified cell type	0.028	0.972	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.028	0.972	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.028	0.972	0.000
C95.0 Acute leukaemia of unspecified cell type	0.028	0.972	0.000
C83.3 Large cell (diffuse)	0.028	0.972	0.000
C90.2 Plasmacytoma, extramedullary	0.028	0.972	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.027	0.973	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.027	0.973	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.027	0.973	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.027	0.973	0.000
C84.3 Lymphoepithelioid lymphoma	0.027	0.973	0.000
C84.2 T-zone lymphoma	0.027	0.973	0.000
C84.1 Sezary's diease	0.027	0.973	0.000
C90.3 Solitary plasmacytoma	0.027	0.973	0.000
C93.9 Monocytic leukaemia, unspecified	0.027	0.973	0.000
C93.7 Other monocytic leukaemia	0.027	0.973	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.027	0.973	0.000
C93.2 Subacute monocytic leukaemia	0.027	0.973	0.000
C93.0 Acute monocytic leukaemia	0.027	0.973	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.027	0.973	0.000
C84.4 Peripheral T-cell lymphoma	0.027	0.973	0.000
C92.4 Acute promyelocytic leukaemia	0.027	0.973	0.000
C91 Lymphoid leukaemia	0.026	0.974	0.000
C90.1 Plasma cell leukaemia	0.025	0.974	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.025	0.975	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.025	0.975	0.000
C86.4 Blastic NK-cell lymphoma	0.025	0.975	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.025	0.975	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.025	0.975	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.025	0.975	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.025	0.975	0.000
C94.7 Other specified leukaemias	0.025	0.975	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.025	0.975	0.000
C94.5 Acute myelofibrosis	0.025	0.975	0.000
C94.4 Acute panmyelosis	0.025	0.975	0.000
C94.3 Mast cell leukaemia	0.025	0.975	0.000
C94.2 Acute megakaryoblastic leukaemia	0.025	0.975	0.000
C94.1 Chronic erythraemia	0.025	0.975	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.025	0.975	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.025	0.975	0.000
C96.8 Histiocytic sarcoma	0.025	0.975	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.025	0.975	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.025	0.975	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.025	0.975	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.025	0.975	0.000
C96.3 True histiocytic lymphoma	0.025	0.975	0.000
C96.2 Malignant mast cell tumour	0.025	0.975	0.000
C96.1 Malignant histiocytosis	0.025	0.975	0.000
C96.0 Letterer-Siwe disease	0.025	0.975	0.000
C91.9 Lymphoid leukaemia, unspecified	0.023	0.977	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.022	0.978	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.978	0.022
E78.2 Mixed hyperlipidaemia	0.001	0.978	0.021
C90.0 Multiple myeloma	0.021	0.979	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.020	0.980	0.000
C85.0 Lymphosarcoma	0.020	0.980	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.019	0.981	0.000
C91.7 Other lymphoid leukaemia	0.019	0.981	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.019	0.981	0.000
C91.3 Prolymphocytic leukaemia	0.019	0.981	0.000
C91.2 Subacute lymphocytic leukaemia	0.019	0.981	0.000
C91.5 Adult T-cell leukaemia	0.019	0.981	0.000
C92.1 Chronic myeloid leukaemia	0.017	0.983	0.000
C91.0 Acute lymphoblastic leukaemia	0.016	0.984	0.000
C85.1 B-cell lymphoma, unspecified	0.016	0.984	0.000
R04.2 Haemoptysis	0.015	0.985	0.000
C91.4 Hairy-cell leukaemia	0.014	0.985	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.985	0.015
I26 Pulmonary embolism	0.000	0.987	0.013
K14.8 Other diseases of tongue	0.000	0.988	0.012
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.011	0.989	0.000
C91.1 Chronic lymphocytic leukaemia	0.011	0.989	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.990	0.010
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.990	0.010
C77.0 Lymph nodes of head, face and neck	0.000	0.990	0.010
N85.2 Hypertrophy of uterus	0.009	0.991	0.000
N85.7 Haematometra	0.007	0.993	0.000
Q50-Q56 Congenital malformations of genital organs	0.007	0.993	0.000
Q54 Hypospadias	0.007	0.993	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.007	0.993	0.000
Q25 Congenital malformations of great arteries	0.007	0.993	0.000
Q66 Congenital deformities of feet	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
Q21.0 Ventricular septal defect	0.007	0.993	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.007	0.993	0.000
Q54.1 Hypospadias, penile	0.006	0.993	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
Q52 Other congenital malformations of female genitalia	0.006	0.994	0.000
Q54.9 Hypospadias, unspecified	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q25.4 Other congenital malformations of aorta	0.006	0.994	0.000
Q25.1 Coarctation of aorta	0.006	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.994	0.006
N85.6 Intra-uterine synechiae	0.006	0.994	0.000
Q53 Undescended testicle	0.006	0.994	0.000
Q66.7 Pes cavus	0.006	0.994	0.000
Q66.3 Other congenital varus deformities of feet	0.006	0.994	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.006	0.994	0.000
Q66.8 Other congenital deformities of feet	0.006	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.006	0.994	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.006	0.994	0.000
Q25.3 Stenosis of aorta	0.005	0.994	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.994	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Z96.6 Presence of orthopaedic joint implants	0.000	0.995	0.005
Q52.4 Other congenital malformations of vagina	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
N85.4 Malposition of uterus	0.005	0.995	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.005	0.995	0.000
Q55 Other congenital malformations of male genital organs	0.005	0.995	0.000
Q52.5 Fusion of labia	0.005	0.995	0.000
N87.1 Moderate cervical dysplasia	0.000	0.995	0.005
Q54.8 Other hypospadias	0.005	0.995	0.000
Q54.4 Congenital chordee	0.005	0.995	0.000
Q54.3 Hypospadias, perineal	0.005	0.995	0.000
Q54.2 Hypospadias, penoscrotal	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.005	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.005	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.005	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.005	0.995	0.000
Q25.2 Atresia of aorta	0.005	0.995	0.000
Q53.1 Undescended testicle, unilateral	0.005	0.995	0.000
Q51 Congenital malformations of uterus and cervix	0.005	0.995	0.000
Q63 Other congenital malformations of kidney	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
K14 Diseases of tongue	0.000	0.995	0.005
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
Q66.0 Talipes equinovarus	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
N85.5 Inversion of uterus	0.005	0.995	0.000
N85.3 Subinvolution of uterus	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.005	0.995	0.000
Q90 Down's syndrome	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
C71.9 Brain, unspecified	0.005	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
Q63.0 Accessory kidney	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
Q67.6 Pectus excavatum	0.005	0.995	0.000
C71.8 Overlapping lesion of brain	0.005	0.995	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.005	0.995	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.005	0.995	0.000
Q52.7 Other congenital malformations of vulva	0.005	0.995	0.000
Q52.6 Congenital malformation of clitoris	0.005	0.995	0.000
Q52.3 Imperforate hymen	0.005	0.995	0.000
Q52.2 Congenital rectovaginal fistula	0.005	0.995	0.000
Q52.1 Doubling of vagina	0.005	0.995	0.000
Q52.0 Congenital absence of vagina	0.005	0.995	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
Q96 Turner's syndrome	0.005	0.995	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.995	0.000
Q21.3 Tetralogy of Fallot	0.004	0.995	0.000
Q21.2 Atrioventricular septal defect	0.004	0.995	0.000
C71 Malignant neoplasm of brain	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.004	0.995	0.000
Q62.5 Duplication of ureter	0.005	0.995	0.000
Q82 Other congenital malformations of skin	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.004	0.995	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.995	0.000
Q54.0 Hypospadias, balanic	0.004	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.995	0.000
Q53.9 Undescended testicle, unspecified	0.004	0.995	0.000
Q53.2 Undescended testicle, bilateral	0.004	0.995	0.000
Q53.0 Ectopic testis	0.004	0.995	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q90.9 Down's syndrome, unspecified	0.004	0.996	0.000
R04 Haemorrhage from respiratory passages	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.996	0.004
K14.6 Glossodynia	0.000	0.996	0.004
Q82.2 Mastocytosis	0.004	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.996	0.004
Q83 Congenital malformations of breast	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.996	0.004
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
C71.1 Frontal lobe	0.004	0.996	0.000
Q89 Other congenital malformations, not elsewhere classified	0.004	0.996	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.996	0.004
C71.3 Parietal lobe	0.004	0.996	0.000
Q51.3 Bicornate uterus	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
N85.1 Endometrial adenomatous hyperplasia	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
Q56.4 Indeterminate sex, unspecified	0.004	0.996	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.004	0.996	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.004	0.996	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.004	0.996	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.004	0.996	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.004	0.996	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.004	0.996	0.000
Q55.5 Congenital absence and aplasia of penis	0.004	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.004	0.996	0.000
Q55.3 Atresia of vas deferens	0.004	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.996	0.000
Q55.1 Hypoplasia of testis and scrotum	0.004	0.996	0.000
Q55.0 Absence and aplasia of testis	0.004	0.996	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.996	0.004
Q55.6 Other congenital malformations of penis	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.996	0.000
Q33 Congenital malformations of lung	0.004	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
Q30 Congenital malformations of nose	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.004	0.996	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.004	0.996	0.000
Q51.6 Embryonic cyst of cervix	0.004	0.996	0.000
Q51.5 Agenesis and aplasia of cervix	0.004	0.996	0.000
Q51.4 Unicornate uterus	0.004	0.996	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.004	0.996	0.000
Q51.0 Agenesis and aplasia of uterus	0.004	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.004	0.996	0.000
Q63.8 Other specified congenital malformations of kidney	0.004	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.004	0.996	0.000
Q63.2 Ectopic kidney	0.004	0.996	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.004	0.996	0.000
K14.5 Plicated tongue	0.000	0.996	0.004
K14.4 Atrophy of tongue papillae	0.000	0.996	0.004
K14.3 Hypertrophy of tongue papillae	0.000	0.996	0.004
K14.2 Median rhomboid glossitis	0.000	0.996	0.004
K14.1 Geographic tongue	0.000	0.996	0.004
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.996	0.000
Y60.0 During surgical operation	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.004	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.004	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.004	0.996	0.000
Q74.1 Congenital malformation of knee	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.004	0.996	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.004	0.996	0.000
Q79.5 Other congenital malformations of abdominal wall	0.004	0.996	0.000
Q79.4 Prune belly syndrome	0.004	0.996	0.000
Q79.3 Gastroschisis	0.004	0.996	0.000
Q79.2 Exomphalos	0.004	0.996	0.000
Q79.1 Other congenital malformations of diaphragm	0.004	0.996	0.000
Q79.0 Congenital diaphragmatic hernia	0.004	0.996	0.000
Q90.2 Trisomy 21, translocation	0.004	0.996	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.004	0.996	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.004	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.996	0.000
Q68.3 Congenital bowing of femur	0.004	0.996	0.000
Q68.2 Congenital deformity of knee	0.004	0.996	0.000
Q68.1 Congenital deformity of hand	0.004	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.996	0.000
Q69.9 Polydactyly, unspecified	0.004	0.996	0.000
Q69.2 Accessory toe(s)	0.004	0.996	0.000
Q69.1 Accessory thumb(s)	0.004	0.996	0.000
Q69.0 Accessory finger(s)	0.004	0.996	0.000
Q70.9 Syndactyly, unspecified	0.004	0.996	0.000
Q70.4 Polysyndactyly	0.004	0.996	0.000
Q70.3 Webbed toes	0.004	0.996	0.000
Q70.2 Fused toes	0.004	0.996	0.000
Q70.1 Webbed fingers	0.004	0.996	0.000
Q70.0 Fused fingers	0.004	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.996	0.000
Q71.6 Lobster-claw hand	0.004	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.004	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.004	0.996	0.000
Q72.7 Split foot	0.004	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.004	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.004	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.004	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.004	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.004	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.004	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.004	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.004	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.004	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.004	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.004	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.004	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.004	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.004	0.996	0.000
Q75.3 Macrocephaly	0.004	0.996	0.000
Q75.2 Hypertelorism	0.004	0.996	0.000
Q75.1 Craniofacial dysostosis	0.004	0.996	0.000
Q75.0 Craniosynostosis	0.004	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.4 Achondroplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
D25.1 Intramural leiomyoma of uterus	0.004	0.996	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.996	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.004	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.004	0.996	0.000
Q78.6 Multiple congenital exostoses	0.004	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.004	0.996	0.000
Q78.4 Enchondromatosis	0.004	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.004	0.996	0.000
Q78.2 Osteopetrosis	0.004	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.004	0.996	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.004	0.996	0.000
Q64.8 Other specified congenital malformations of urinary system	0.004	0.996	0.000
Q64.6 Congenital diverticulum of bladder	0.004	0.996	0.000
Q64.5 Congenital absence of bladder and urethra	0.004	0.996	0.000
Q64.4 Malformation of urachus	0.004	0.996	0.000
Q64.2 Congenital posterior urethral valves	0.004	0.996	0.000
Q64.1 Exstrophy of urinary bladder	0.004	0.996	0.000
Q64.0 Epispadias	0.004	0.996	0.000
Q83.8 Other congenital malformations of breast	0.004	0.996	0.000
C71.4 Occipital lobe	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.996	0.000
Q51.2 Other doubling of uterus	0.003	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.996	0.000
Z99.3 Dependence on wheelchair	0.000	0.996	0.004
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.996	0.000
Q17 Other congenital malformations of ear	0.003	0.996	0.000
N84.2 Polyp of vagina	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.996	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.003	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.003	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.996	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.003	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations