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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77348922
log Bayes Factor = 13.2588
Chromosome 4   position 126,748,209  (GRCh37) Explore rs77348922 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.999 0.001 0.000
R30-R39 Symptoms and signs involving the urinary system
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
R35 Polyuria
0.993 0.007 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.989 0.011 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.986 0.014 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
G40-G47 Episodic and paroxysmal disorders
0.986 0.014 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.986 0.014 0.000
R39 Other symptoms and signs involving the urinary system
0.981 0.019 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.977 0.023 0.000
R39.1 Other difficulties with micturition
0.976 0.024 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.976 0.024 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.973 0.027 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
G40 Epilepsy
0.969 0.031 0.000
K83 Other diseases of biliary tract
0.961 0.039 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.961 0.039 0.000
K55-K64 Other diseases of intestines
0.960 0.040 0.000
Chapter V Mental and behavioural disorders
0.960 0.040 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.957 0.043 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.953 0.047 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.947 0.053 0.000
Chapter IX Diseases of the circulatory system
0.945 0.055 0.000
S50-S59 Injuries to the elbow and forearm
0.943 0.057 0.000
R94 Abnormal results of function studies
0.940 0.060 0.000
Chapter X Diseases of the respiratory system
0.940 0.060 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.939 0.061 0.000
K63 Other diseases of intestine
0.938 0.062 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.937 0.063 0.000
I30-I52 Other forms of heart disease
0.935 0.065 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.933 0.067 0.000
K63.8 Other specified diseases of intestine
0.932 0.068 0.000
G57 Mononeuropathies of lower limb
0.931 0.069 0.000
K35-K38 Diseases of appendix
0.930 0.070 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.926 0.074 0.000
K81 Cholecystitis
0.926 0.074 0.000
Z92 Personal history of medical treatment
0.924 0.076 0.000
T43.2 Other and unspecified antidepressants
0.915 0.085 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.914 0.086 0.000
Z13 Special screening examination for other diseases and disorders
0.911 0.089 0.000
K02 Dental caries
0.906 0.094 0.000
W00-W19 Falls
0.906 0.094 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.904 0.096 0.000
Z12 Special screening examination for neoplasms
0.903 0.097 0.000
K83.0 Cholangitis
0.903 0.097 0.000
J20-J22 Other acute lower respiratory infections
0.898 0.102 0.000
S52 Fracture of forearm
0.890 0.110 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.889 0.111 0.000
R94.5 Abnormal results of liver function studies
0.887 0.113 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.886 0.114 0.000
Z01.8 Other specified special examinations
0.883 0.117 0.000
Z88.6 Personal history of allergy to analgesic agent
0.883 0.117 0.000
R26 Abnormalities of gait and mobility
0.880 0.120 0.000
K02.9 Dental caries, unspecified
0.880 0.120 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.879 0.121 0.000
G47 Sleep disorders
0.873 0.127 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.873 0.127 0.000
J22 Unspecified acute lower respiratory infection
0.869 0.131 0.000
R42 Dizziness and giddiness
0.868 0.132 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.866 0.134 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.865 0.135 0.000
I49 Other cardiac arrhythmias
0.865 0.135 0.000
G57.6 Lesion of plantar nerve
0.865 0.135 0.000
F30-F39 Mood [affective] disorders
0.863 0.137 0.000
S52.5 Fracture of lower end of radius
0.859 0.141 0.000
J09-J18 Influenza and pneumonia
0.858 0.142 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.857 0.143 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.854 0.146 0.000
K81.0 Acute cholecystitis
0.854 0.146 0.000
K37 Unspecified appendicitis
0.854 0.146 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.853 0.147 0.000
K59 Other functional intestinal disorders
0.852 0.148 0.000
W19 Unspecified fall
0.851 0.149 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.850 0.150 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.847 0.153 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.842 0.158 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.840 0.160 0.000
K58 Irritable bowel syndrome
0.840 0.160 0.000
S52.50 Fracture of lower end of radius (closed)
0.837 0.163 0.000
I44 Atrioventricular and left bundle-branch block
0.836 0.164 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.834 0.166 0.000
R47-R49 Symptoms and signs involving speech and voice
0.830 0.170 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.827 0.173 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.825 0.174 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.824 0.176 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.823 0.177 0.000
I51 Complications and ill-defined descriptions of heart disease
0.821 0.179 0.000
J18 Pneumonia, organism unspecified
0.819 0.181 0.000
G50 Disorders of trigeminal nerve
0.819 0.181 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.818 0.182 0.000
Z83 Family history of other specific disorders
0.817 0.183 0.000
W19.9 Unspecified place
0.815 0.185 0.000
K81.1 Chronic cholecystitis
0.814 0.186 0.000
S70-S79 Injuries to the hip and thigh
0.812 0.188 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.811 0.189 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.808 0.192 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.808 0.192 0.000
G51 Facial nerve disorders
0.807 0.193 0.000
Z89 Acquired absence of limb
0.807 0.193 0.000
J00-J06 Acute upper respiratory infections
0.806 0.194 0.000
I47 Paroxysmal tachycardia
0.806 0.194 0.000
K83.1 Obstruction of bile duct
0.804 0.196 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.804 0.196 0.000
G35 Multiple sclerosis
0.803 0.197 0.000
L03 Cellulitis
0.803 0.197 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.801 0.199 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.801 0.199 0.000
S40-S49 Injuries to the shoulder and upper arm
0.801 0.199 0.000
K83.8 Other specified diseases of biliary tract
0.800 0.200 0.000
K86 Other diseases of pancreas
0.799 0.201 0.000
G57.8 Other mononeuropathies of lower limb
0.798 0.202 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.797 0.203 0.000
R02 Gangrene, not elsewhere classified
0.789 0.211 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.789 0.211 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.786 0.214 0.000
I05-I09 Chronic rheumatic heart diseases
0.782 0.218 0.000
I38 Endocarditis, valve unspecified
0.781 0.219 0.000
Y52 Agents primarily affecting the cardiovascular system
0.781 0.219 0.000
R40 Somnolence, stupor and coma
0.780 0.220 0.000
R25 Abnormal involuntary movements
0.779 0.221 0.000
R27 Other lack of coordination
0.777 0.223 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.777 0.223 0.000
K08 Other disorders of teeth and supporting structures
0.775 0.225 0.000
G30-G32 Other degenerative diseases of the nervous system
0.774 0.226 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.773 0.227 0.000
K80 Cholelithiasis
0.772 0.228 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.770 0.230 0.000
S90-S99 Injuries to the ankle and foot
0.769 0.231 0.000
G47.3 Sleep apnoea
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.768 0.232 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.768 0.232 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.767 0.233 0.000
I46 Cardiac arrest
0.767 0.233 0.000
Z99.1 Dependence on respirator
0.766 0.234 0.000
V20-V29 Motorcycle rider injured in transport accident
0.764 0.235 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.764 0.236 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.762 0.238 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.761 0.239 0.000
F33 Recurrent depressive disorder
0.761 0.239 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.760 0.240 0.000
G40.9 Epilepsy, unspecified
0.760 0.240 0.000
S51 Open wound of forearm
0.758 0.242 0.000
G90-G99 Other disorders of the nervous system
0.757 0.243 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.757 0.243 0.000
R94.3 Abnormal results of cardiovascular function studies
0.757 0.243 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.756 0.244 0.000
K63.9 Disease of intestine, unspecified
0.755 0.245 0.000
Chapter XIV Diseases of the genitourinary system
0.755 0.245 0.000
Z13.9 Special screening examination, unspecified
0.754 0.246 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.754 0.246 0.000
K59.0 Constipation
0.753 0.247 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.753 0.247 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.752 0.248 0.000
K05 Gingivitis and periodontal diseases
0.751 0.249 0.000
I49.0 Ventricular fibrillation and flutter
0.751 0.249 0.000
L20-L30 Dermatitis and eczema
0.751 0.249 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.750 0.250 0.000
G58 Other mononeuropathies
0.750 0.250 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.749 0.251 0.000
G41 Status epilepticus
0.748 0.252 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.746 0.254 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.746 0.254 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.741 0.259 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.739 0.261 0.000
F31 Bipolar affective disorder
0.739 0.261 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.737 0.263 0.000
L03.1 Cellulitis of other parts of limb
0.737 0.263 0.000
R06 Abnormalities of breathing
0.736 0.264 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.736 0.264 0.000
J60-J70 Lung diseases due to external agents
0.734 0.266 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.734 0.266 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.734 0.266 0.000
T79-T79 Certain early complications of trauma
0.734 0.266 0.000
Z81 Family history of mental and behavioural disorders
0.733 0.266 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.733 0.267 0.000
G56 Mononeuropathies of upper limb
0.733 0.267 0.000
K38 Other diseases of appendix
0.731 0.269 0.000
K01 Embedded and impacted teeth
0.731 0.269 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.731 0.269 0.000
S52.6 Fracture of lower end of both ulna and radius
0.730 0.270 0.000
I44.7 Left bundle-branch block, unspecified
0.730 0.270 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.730 0.270 0.000
R30 Pain associated with micturition
0.730 0.270 0.000
F99-F99 Unspecified mental disorder
0.728 0.272 0.000
Z85 Personal history of malignant neoplasm
0.726 0.274 0.000
R44.1 Visual hallucinations
0.725 0.275 0.000
I30 Acute pericarditis
0.723 0.277 0.000
K09 Cysts of oral region, not elsewhere classified
0.723 0.277 0.000
J18.0 Bronchopneumonia, unspecified
0.721 0.278 0.000
J18.1 Lobar pneumonia, unspecified
0.720 0.280 0.000
I44.2 Atrioventricular block, complete
0.720 0.280 0.000
Z88.0 Personal history of allergy to penicillin
0.719 0.281 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.718 0.282 0.000
Z92.3 Personal history of irradiation
0.718 0.282 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R45 Symptoms and signs involving emotional state
0.716 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.716 0.284 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.715 0.285 0.000
R36 Urethral discharge
0.715 0.285 0.000
R34 Anuria and oliguria
0.715 0.285 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
R04 Haemorrhage from respiratory passages
0.713 0.287 0.000
N10-N16 Renal tubulo-interstitial diseases
0.712 0.288 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.712 0.288 0.000
I51.7 Cardiomegaly
0.712 0.288 0.000
I42 Cardiomyopathy
0.711 0.289 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.709 0.291 0.000
Y40 Systemic antibiotics
0.709 0.291 0.000
Z09.4 Follow-up examination after treatment of fracture
0.707 0.293 0.000
Z09.3 Follow-up examination after psychotherapy
0.707 0.293 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.707 0.293 0.000
K35 Acute appendicitis
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.707 0.293 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.707 0.293 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.707 0.293 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
R94.4 Abnormal results of kidney function studies
0.705 0.295 0.000
G50.0 Trigeminal neuralgia
0.705 0.295 0.000
G70-G73 Diseases of myoneural junction and muscle
0.704 0.296 0.000
V10-V19 Pedal cyclist injured in transport accident
0.703 0.296 0.000
R39.2 Extrarenal uraemia
0.703 0.296 0.000
R39.0 Extravasation of urine
0.703 0.296 0.000
K11 Diseases of salivary glands
0.703 0.297 0.000
Z89.4 Acquired absence of foot and ankle
0.703 0.297 0.000
Z04 Examination and observation for other reasons
0.701 0.298 0.000
K02.8 Other dental caries
0.701 0.299 0.000
G54 Nerve root and plexus disorders
0.700 0.299 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.700 0.299 0.000
G52 Disorders of other cranial nerves
0.700 0.299 0.000
W20-W49 Exposure to inanimate mechanical forces
0.700 0.299 0.000
Z01.6 Radiological examination, not elsewhere classified
0.700 0.300 0.000
I84 Haemorrhoids
0.699 0.301 0.000
F60-F69 Disorders of adult personality and behaviour
0.698 0.302 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.698 0.302 0.000
R46 Symptoms and signs involving appearance and behaviour
0.697 0.302 0.000
R43 Disturbances of smell and taste
0.697 0.302 0.000
Z83.7 Family history of diseases of the digestive system
0.697 0.303 0.000
Z92.0 Personal history of contraception
0.696 0.303 0.000
K12 Stomatitis and related lesions
0.695 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
G40.8 Other epilepsy
0.694 0.305 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.694 0.305 0.000
G40.5 Special epileptic syndromes
0.694 0.305 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.694 0.305 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.694 0.305 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.694 0.305 0.000
R29.6 Tendency to fall, not elsewhere classified
0.691 0.309 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.691 0.309 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.691 0.309 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.690 0.310 0.000
K83.9 Disease of biliary tract, unspecified
0.689 0.311 0.000
K83.5 Biliary cyst
0.689 0.311 0.000
K83.4 Spasm of sphincter of Oddi
0.689 0.311 0.000
K83.3 Fistula of bile duct
0.689 0.311 0.000
K83.2 Perforation of bile duct
0.689 0.311 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.688 0.312 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.688 0.312 0.000
F80-F89 Disorders of psychological development
0.688 0.312 0.000
F70-F79 Mental retardation
0.688 0.312 0.000
F33.9 Recurrent depressive disorder, unspecified
0.687 0.313 0.000
K40-K46 Hernia
0.687 0.313 0.000
R05 Cough
0.687 0.313 0.000
Z93 Artificial opening status
0.687 0.313 0.000
R47 Speech disturbances, not elsewhere classified
0.687 0.313 0.000
T43.9 Psychotropic drug, unspecified
0.686 0.314 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.686 0.314 0.000
T43.6 Psychostimulants with abuse potential
0.686 0.314 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.686 0.314 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.686 0.314 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.686 0.314 0.000
Z99.3 Dependence on wheelchair
0.686 0.314 0.000
G51.0 Bell's palsy
0.685 0.315 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.315 0.000
K61 Abscess of anal and rectal regions
0.685 0.315 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.684 0.316 0.000
L89 Decubitus ulcer
0.684 0.316 0.000
I49.9 Cardiac arrhythmia, unspecified
0.683 0.317 0.000
Z84 Family history of other conditions
0.683 0.317 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.683 0.317 0.000
G47.9 Sleep disorder, unspecified
0.682 0.318 0.000
I84.9 Unspecified haemorrhoids without complication
0.682 0.318 0.000
I51.8 Other ill-defined heart diseases
0.682 0.318 0.000
Z91.5 Personal history of self-harm
0.682 0.318 0.000
I49.8 Other specified cardiac arrhythmias
0.681 0.319 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.681 0.319 0.000
I34 Nonrheumatic mitral valve disorders
0.681 0.319 0.000
K55 Vascular disorders of intestine
0.681 0.319 0.000
R31 Unspecified haematuria
0.680 0.320 0.000
L10-L14 Bullous disorders
0.679 0.321 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.679 0.321 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.678 0.321 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.678 0.322 0.000
T39.0 Salicylates
0.678 0.322 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.678 0.322 0.000
L60-L75 Disorders of skin appendages
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.678 0.322 0.000
I00-I02 Acute rheumatic fever
0.678 0.322 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.678 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
R44.0 Auditory hallucinations
0.678 0.322 0.000
W06 Fall involving bed
0.677 0.323 0.000
S59 Other and unspecified injuries of forearm
0.676 0.323 0.000
S58 Traumatic amputation of forearm
0.676 0.323 0.000
S57 Crushing injury of forearm
0.676 0.323 0.000
S56 Injury of muscle and tendon at forearm level
0.676 0.323 0.000
S55 Injury of blood vessels at forearm level
0.676 0.323 0.000
S54 Injury of nerves at forearm level
0.676 0.323 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.676 0.323 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.675 0.325 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.674 0.326 0.000
R94.7 Abnormal results of other endocrine function studies
0.674 0.326 0.000
R94.6 Abnormal results of thyroid function studies
0.674 0.326 0.000
R94.2 Abnormal results of pulmonary function studies
0.674 0.326 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.674 0.326 0.000
R94.0 Abnormal results of function studies of central nervous system
0.674 0.326 0.000
K63.1 Perforation of intestine (nontraumatic)
0.674 0.326 0.000
T51 Toxic effect of alcohol
0.673 0.327 0.000
Z01.9 Special examination, unspecified
0.673 0.327 0.000
Z01.7 Laboratory examination
0.673 0.327 0.000
Z01.3 Examination of blood pressure
0.673 0.327 0.000
Z01.2 Dental examination
0.673 0.327 0.000
Z01.1 Examination of ears and hearing
0.673 0.327 0.000
Z01.0 Examination of eyes and vision
0.673 0.327 0.000
K63.4 Enteroptosis
0.672 0.327 0.000
K63.0 Abscess of intestine
0.672 0.327 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.673 0.327 0.000
J00 Acute nasopharyngitis [common cold]
0.672 0.327 0.000
I49.3 Ventricular premature depolarisation
0.672 0.328 0.000
L03.3 Cellulitis of trunk
0.672 0.328 0.000
K03 Other diseases of hard tissues of teeth
0.671 0.328 0.000
K00 Disorders of tooth development and eruption
0.671 0.328 0.000
T66-T78 Other and unspecified effects of external causes
0.671 0.329 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.671 0.329 0.000
I52 Other heart disorders in diseases classified elsewhere
0.670 0.330 0.000
I48 Atrial fibrillation and flutter
0.670 0.330 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.670 0.330 0.000
I41 Myocarditis in diseases classified elsewhere
0.670 0.330 0.000
I40 Acute myocarditis
0.670 0.330 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.670 0.330 0.000
I37 Pulmonary valve disorders
0.670 0.330 0.000
I36 Nonrheumatic tricuspid valve disorders
0.670 0.330 0.000
I33 Acute and subacute endocarditis
0.670 0.330 0.000
I32 Pericarditis in diseases classified elsewhere
0.670 0.330 0.000
S50 Superficial injury of forearm
0.669 0.330 0.000
W10 Fall on and from stairs and steps
0.668 0.332 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.667 0.333 0.000
G57.5 Tarsal tunnel syndrome
0.667 0.333 0.000
G57.4 Lesion of medial popliteal nerve
0.667 0.333 0.000
G57.3 Lesion of lateral popliteal nerve
0.667 0.333 0.000
G57.2 Lesion of femoral nerve
0.667 0.333 0.000
G57.1 Meralgia paraesthetica
0.667 0.333 0.000
G57.0 Lesion of sciatic nerve
0.667 0.333 0.000
K36 Other appendicitis
0.667 0.333 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.667 0.333 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.667 0.333 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.666 0.334 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.665 0.335 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.664 0.336 0.000
I47.1 Supraventricular tachycardia
0.664 0.336 0.000
K81.8 Other cholecystitis
0.664 0.336 0.000
Z01.4 Gynaecological examination (general)(routine)
0.663 0.337 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.663 0.337 0.000
Z92.9 Personal history of medical treatment, unspecified
0.662 0.337 0.000
Z92.8 Personal history of other medical treatment
0.662 0.337 0.000
Z92.5 Personal history of rehabilitation measures
0.662 0.337 0.000
J18.9 Pneumonia, unspecified
0.662 0.338 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.338 0.000
R01 Cardiac murmurs and other cardiac sounds
0.661 0.339 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.661 0.339 0.000
I08 Multiple valve diseases
0.660 0.340 0.000
K70-K77 Diseases of liver
0.660 0.340 0.000
J04 Acute laryngitis and tracheitis
0.659 0.341 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.659 0.341 0.000
L40-L45 Papulosquamous disorders
0.658 0.342 0.000
G37 Other demyelinating diseases of central nervous system
0.657 0.343 0.000
R41.3 Other amnesia
0.657 0.343 0.000
I47.2 Ventricular tachycardia
0.656 0.344 0.000
L50-L54 Urticaria and erythema
0.656 0.344 0.000
O60-O75 Complications of labour and delivery
0.656 0.344 0.000
S72 Fracture of femur
0.656 0.344 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.655 0.345 0.000
Y57 Other and unspecified drugs and medicaments
0.655 0.345 0.000
Q50-Q56 Congenital malformations of genital organs
0.655 0.345 0.000
I49.5 Sick sinus syndrome
0.654 0.346 0.000
R25.2 Cramp and spasm
0.654 0.346 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.653 0.347 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.653 0.347 0.000
Z13.5 Special screening examination for eye and ear disorders
0.653 0.347 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.653 0.347 0.000
Z13.2 Special screening examination for nutritional disorders
0.653 0.347 0.000
Y44 Agents primarily affecting blood constituents
0.652 0.348 0.000
K50-K52 Noninfective enteritis and colitis
0.651 0.349 0.000
T39.1 4-Aminophenol derivatives
0.650 0.350 0.000
K02.5 Caries with pulp exposure
0.650 0.350 0.000
K02.4 Odontoclasia
0.650 0.350 0.000
K02.3 Arrested dental caries
0.650 0.350 0.000
K02.2 Caries of cementum
0.650 0.350 0.000
K02.1 Caries of dentin
0.650 0.350 0.000
K02.0 Caries limited to enamel
0.650 0.350 0.000
L82 Seborrhoeic keratosis
0.650 0.350 0.000
W18 Other fall on same level
0.649 0.350 0.000
W17 Other fall from one level to another
0.649 0.350 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.649 0.350 0.000
W15 Fall from cliff
0.649 0.350 0.000
W14 Fall from tree
0.649 0.350 0.000
W13 Fall from, out of or through building or structure
0.649 0.350 0.000
W12 Fall on and from scaffolding
0.649 0.350 0.000
W11 Fall on and from ladder
0.649 0.350 0.000
W09 Fall involving playground equipment
0.649 0.350 0.000
W08 Fall involving other furniture
0.649 0.350 0.000
W07 Fall involving chair
0.649 0.350 0.000
W05 Fall involving wheelchair
0.649 0.350 0.000
W04 Fall while being carried or supported by other persons
0.649 0.350 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.649 0.350 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.649 0.350 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.649 0.350 0.000
W00 Fall on same level involving ice and snow
0.649 0.350 0.000
I49.1 Atrial premature depolarisation
0.649 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.648 0.351 0.000
Y58 Bacterial vaccines
0.648 0.351 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.648 0.351 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.648 0.351 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.648 0.351 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.648 0.351 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.648 0.351 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.648 0.351 0.000
Y48 Anaesthetics and therapeutic gases
0.648 0.351 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.648 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.648 0.351 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.648 0.351 0.000
J95-J99 Other diseases of the respiratory system
0.648 0.352 0.000
G44 Other headache syndromes
0.648 0.352 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.648 0.352 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.648 0.352 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.648 0.352 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.648 0.352 0.000
Z12.3 Special screening examination for neoplasm of breast
0.648 0.352 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.648 0.352 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.648 0.352 0.000
S60-S69 Injuries to the wrist and hand
0.646 0.354 0.000
Z97 Presence of other devices
0.646 0.354 0.000
R06.0 Dyspnoea
0.646 0.354 0.000
X60-X84 Intentional self-harm
0.646 0.354 0.000
I46.0 Cardiac arrest with successful resuscitation
0.646 0.354 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.645 0.354 0.000
K59.1 Functional diarrhoea
0.645 0.355 0.000
K10 Other diseases of jaws
0.644 0.356 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.644 0.356 0.000
J21 Acute bronchiolitis
0.644 0.356 0.000
J20 Acute bronchitis
0.644 0.356 0.000
K85 Acute pancreatitis
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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