TreeWAS – Variant ID: rs7740706

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86.9 Sarcoidosis, unspecified	0.077	0.923	0.000
D86 Sarcoidosis	0.053	0.947	0.000
D86.0 Sarcoidosis of lung	0.041	0.959	0.000
D86.8 Sarcoidosis of other and combined sites	0.040	0.960	0.000
D86.3 Sarcoidosis of skin	0.039	0.961	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.037	0.963	0.000
D80-D89 Certain disorders involving the immune mechanism	0.037	0.963	0.000
D80 Immunodeficiency with predominantly antibody defects	0.036	0.964	0.000
D86.1 Sarcoidosis of lymph nodes	0.033	0.967	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.031	0.969	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.029	0.971	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.029	0.971	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.028	0.971	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.028	0.972	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.028	0.972	0.000
D83 Common variable immunodeficiency	0.028	0.972	0.000
D81 Combined immunodeficiencies	0.027	0.973	0.000
D82 Immunodeficiency associated with other major defects	0.026	0.974	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.026	0.974	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.026	0.974	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.026	0.974	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.024	0.975	0.000
D84 Other immunodeficiencies	0.022	0.978	0.000
D83.9 Common variable immunodeficiency, unspecified	0.021	0.979	0.000
E21.0 Primary hyperparathyroidism	0.021	0.979	0.000
D83.8 Other common variable immunodeficiencies	0.020	0.980	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.020	0.980	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.020	0.980	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.020	0.980	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.020	0.980	0.000
E21.3 Hyperparathyroidism, unspecified	0.020	0.980	0.000
D81.9 Combined immunodeficiency, unspecified	0.019	0.981	0.000
D81.8 Other combined immunodeficiencies	0.019	0.981	0.000
D81.7 Major histocompatibility complex class II deficiency	0.019	0.981	0.000
D81.6 Major histocompatibility complex class I deficiency	0.019	0.981	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.019	0.981	0.000
D81.4 Nezelof's syndrome	0.019	0.981	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.019	0.981	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.019	0.981	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.019	0.981	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.019	0.981	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.019	0.981	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.019	0.981	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.019	0.981	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.019	0.981	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.019	0.981	0.000
D82.2 Immunodeficiency with short-limbed stature	0.019	0.981	0.000
D82.0 Wiskott-Aldrich syndrome	0.019	0.981	0.000
D82.1 Di George's syndrome	0.018	0.982	0.000
D84.8 Other specified immunodeficiencies	0.016	0.984	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.016	0.984	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.016	0.984	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.015	0.985	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.015	0.985	0.000
E21.4 Other specified disorders of parathyroid gland	0.015	0.985	0.000
D89.3 Immune reconstitution syndrome	0.014	0.985	0.000
D84.1 Defects in the complement system	0.014	0.986	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.014	0.986	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.014	0.986	0.000
D89.1 Cryoglobulinaemia	0.013	0.986	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.013	0.987	0.000
E21.2 Other hyperparathyroidism	0.013	0.987	0.000
D84.9 Immunodeficiency, unspecified	0.013	0.987	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.012	0.988	0.000
G25 Other extrapyramidal and movement disorders	0.011	0.989	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.989	0.011
D59.1 Other autoimmune haemolytic anaemias	0.010	0.990	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.991	0.009
D59 Acquired haemolytic anaemia	0.009	0.991	0.000
G25.0 Essential tremor	0.009	0.991	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.009	0.991	0.000
D55-D59 Haemolytic anaemias	0.009	0.991	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
G25.5 Other chorea	0.009	0.991	0.000
G25.3 Myoclonus	0.008	0.992	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.008	0.992	0.000
G25.4 Drug-induced chorea	0.008	0.992	0.000
G25.2 Other specified forms of tremor	0.008	0.992	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.007	0.993	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.007	0.993	0.000
D59.8 Other acquired haemolytic anaemias	0.007	0.993	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.007	0.993	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.007	0.993	0.000
D59.3 Haemolytic-uraemic syndrome	0.007	0.993	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.007	0.993	0.000
D57 Sickle-cell disorders	0.007	0.993	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.993	0.007
D56 Thalassaemia	0.007	0.993	0.000
D55 Anaemia due to enzyme disorders	0.006	0.993	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.006	0.994	0.000
G25.1 Drug-induced tremor	0.006	0.994	0.000
D50-D53 Nutritional anaemias	0.006	0.994	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.006	0.994	0.000
D50 Iron deficiency anaemia	0.006	0.994	0.000
D58 Other hereditary haemolytic anaemias	0.006	0.994	0.000
N60.8 Other benign mammary dysplasias	0.006	0.994	0.000
M70.22 Olecranon bursitis-Upper arm	0.006	0.994	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.006	0.994	0.000
H33.0 Retinal detachment with retinal break	0.006	0.994	0.000
D57.1 Sickle-cell anaemia without crisis	0.005	0.994	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.005	0.995	0.000
S22.4 Multiple fractures of ribs	0.000	0.995	0.005
D56.3 Thalassaemia trait	0.005	0.995	0.000
D57.8 Other sickle-cell disorders	0.005	0.995	0.000
D57.3 Sickle-cell trait	0.005	0.995	0.000
D57.2 Double heterozygous sickling disorders	0.005	0.995	0.000
D57.0 Sickle-cell anaemia with crisis	0.005	0.995	0.000
D56.9 Thalassaemia, unspecified	0.005	0.995	0.000
D56.8 Other thalassaemias	0.005	0.995	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.005	0.995	0.000
D56.2 Delta-beta thalassaemia	0.005	0.995	0.000
D56.0 Alpha thalassaemia	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.005	0.995	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.005	0.995	0.000
D55.8 Other anaemias due to enzyme disorders	0.005	0.995	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.005	0.995	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.005	0.995	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.005	0.995	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.005	0.995	0.000
D50.8 Other iron deficiency anaemias	0.005	0.995	0.000
T68 Hypothermia	0.000	0.995	0.005
D56.1 Beta thalassaemia	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.005	0.995	0.000
D53 Other nutritional anaemias	0.005	0.995	0.000
D50.1 Sideropenic dysphagia	0.005	0.995	0.000
G20-G26 Extrapyramidal and movement disorders	0.005	0.995	0.000
G24.9 Dystonia, unspecified	0.005	0.995	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.004	0.996	0.000
D58.1 Hereditary elliptocytosis	0.004	0.996	0.000
G24 Dystonia	0.004	0.996	0.000
E27.2 Addisonian crisis	0.004	0.996	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.996	0.004
S22.41 Multiple fractures of ribs (open)	0.000	0.996	0.004
E20 Hypoparathyroidism	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
G21 Secondary Parkinsonism	0.004	0.996	0.000
D58.2 Other haemoglobinopathies	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
E25 Adrenogenital disorders	0.004	0.996	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.004	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.996	0.004
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E26 Hyperaldosteronism	0.004	0.996	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.004	0.996	0.000
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
F99 Mental disorder, not otherwise specified	0.000	0.996	0.004
M70.2 Olecranon bursitis	0.004	0.996	0.000
G23 Other degenerative diseases of basal ganglia	0.004	0.996	0.000
D66 Hereditary factor VIII deficiency	0.004	0.996	0.000
D53.9 Nutritional anaemia, unspecified	0.004	0.996	0.000
D53.8 Other specified nutritional anaemias	0.003	0.996	0.000
D53.2 Scorbutic anaemia	0.003	0.996	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.996	0.000
D53.0 Protein deficiency anaemia	0.003	0.996	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.996	0.004
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.004	0.996	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.004	0.996	0.000
G22 Parkinsonism in diseases classified elsewhere	0.004	0.996	0.000
Q61 Cystic kidney disease	0.000	0.996	0.004
E24 Cushing's syndrome	0.003	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.000	0.996	0.004
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
G21.4 Vascular parkinsonism	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
D52 Folate deficiency anaemia	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
M87.9 Osteonecrosis, unspecified	0.003	0.997	0.000
T71 Asphyxiation	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
G24.4 Idiopathic orofacial dystonia	0.003	0.997	0.000
G24.2 Idiopathic nonfamilial dystonia	0.003	0.997	0.000
G24.8 Other dystonia	0.003	0.997	0.000
G24.3 Spasmodic torticollis	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
G24.0 Drug-induced dystonia	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.997	0.003
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
G21.0 Malignant neuroleptic syndrome	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.997	0.003
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.000	0.997	0.003
G21.9 Secondary Parkinsonism, unspecified	0.003	0.997	0.000
G21.8 Other secondary Parkinsonism	0.003	0.997	0.000
G21.3 Postencephalitic Parkinsonism	0.003	0.997	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.003	0.997	0.000
G24.1 Idiopathic familial dystonia	0.003	0.997	0.000
N85.2 Hypertrophy of uterus	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
G24.5 Blepharospasm	0.003	0.997	0.000
M70.23 Olecranon bursitis-Forearm	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
D58.0 Hereditary spherocytosis	0.003	0.997	0.001
J32.4 Chronic pansinusitis	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.000	0.997	0.003
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.003	0.997	0.000
D76.3 Other histiocytosis syndromes	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
M70.29 Olecranon bursitis-Site unspec	0.003	0.997	0.000
M70.28 Olecranon bursitis-Other	0.003	0.997	0.000
M70.27 Olecranon bursitis-Ankle/Foot	0.003	0.997	0.000
M70.26 Olecranon bursitis-Lower Leg	0.003	0.997	0.000
M70.25 Olecranon bursitis-Pelvic/Thigh	0.003	0.997	0.000
M70.24 Olecranon bursitis-Hand	0.003	0.997	0.000
M70.21 Olecranon bursitis-Shldr region	0.003	0.997	0.000
M70.20 Olecranon bursitis-Mult sites	0.003	0.997	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.003	0.997	0.000
G23.3 Multiple system atrophy, cerebellar type	0.003	0.997	0.000
G23.2 Striatonigral degeneration	0.003	0.997	0.000
G23.0 Hallervorden-Spatz disease	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.000	0.997	0.003
M87.96 Osteonecrosis, unspecified (Lower leg)	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
K11.8 Other diseases of salivary glands	0.000	0.997	0.003
G23.8 Other specified degenerative diseases of basal ganglia	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.997	0.003
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.003	0.997	0.000
E87.5 Hyperkalaemia	0.003	0.997	0.000
T75 Effects of other external causes	0.000	0.997	0.003
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
I05.0 Mitral stenosis	0.000	0.997	0.003
Q61.8 Other cystic kidney diseases	0.000	0.997	0.003
Q61.1 Polycystic kidney, infantile type	0.000	0.997	0.003
T78 Adverse effects, not elsewhere classified	0.000	0.997	0.003
E29.1 Testicular hypofunction	0.003	0.997	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.997	0.003
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.003	0.997	0.000
T74 Maltreatment syndromes	0.000	0.997	0.003
T73 Effects of other deprivation	0.000	0.997	0.003
T69 Other effects of reduced temperature	0.000	0.997	0.003
T67 Effects of heat and light	0.000	0.997	0.003
D52.8 Other folate deficiency anaemias	0.003	0.997	0.000
D52.1 Drug-induced folate deficiency anaemia	0.003	0.997	0.000
D52.0 Dietary folate deficiency anaemia	0.003	0.997	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.003	0.997	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.003	0.997	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.003	0.997	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.003	0.997	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.003	0.997	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
O32.2 Maternal care for transverse and oblique lie	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
Y83.4 Other reconstructive surgery	0.000	0.997	0.003
J32 Chronic sinusitis	0.000	0.997	0.003
S62.51 Fracture of thumb (open)	0.003	0.997	0.000
I63 Cerebral infarction	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.997	0.000
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
T75.4 Effects of electric current	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.002	0.997	0.000
E34.0 Carcinoid syndrome	0.002	0.997	0.000
G72.0 Drug-induced myopathy	0.000	0.997	0.003
D51.2 Transcobalamin II deficiency	0.002	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.997	0.000
T70 Effects of air pressure and water pressure	0.000	0.997	0.002
M20.0 Deformity of finger(s)	0.000	0.997	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.000
J32.1 Chronic frontal sinusitis	0.000	0.997	0.002
M18 Arthrosis of first carpometacarpal joint	0.000	0.997	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
E28 Ovarian dysfunction	0.002	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.998	0.002
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
T75.8 Other specified effects of external causes	0.000	0.998	0.002
T75.3 Motion sickness	0.000	0.998	0.002
T75.2 Effects of vibration	0.000	0.998	0.002
T75.0 Effects of lightning	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
G50.0 Trigeminal neuralgia	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
G72 Other myopathies	0.000	0.998	0.002
B02.9 Zoster without complication	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
M25.55 Pain in joint (Pelvic region and thigh)	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.002
T67.8 Other effects of heat and light	0.000	0.998	0.002
T67.7 Heat oedema	0.000	0.998	0.002
T67.6 Heat fatigue, transient	0.000	0.998	0.002
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.002
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.002
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.002
T67.2 Heat cramp	0.000	0.998	0.002
T67.1 Heat syncope	0.000	0.998	0.002
T67.0 Heatstroke and sunstroke	0.000	0.998	0.002
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.002
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.002
T69.1 Chilblains	0.000	0.998	0.002
T69.0 Immersion hand and foot	0.000	0.998	0.002
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.002
T73.8 Other effects of deprivation	0.000	0.998	0.002
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.002
T73.2 Exhaustion due to exposure	0.000	0.998	0.002
T73.1 Effects of thirst	0.000	0.998	0.002
T73.0 Effects of hunger	0.000	0.998	0.002
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.002
T74.8 Other maltreatment syndromes	0.000	0.998	0.002
T74.3 Psychological abuse	0.000	0.998	0.002
T74.2 Sexual abuse	0.000	0.998	0.002
T74.1 Physical abuse	0.000	0.998	0.002
T74.0 Neglect or abandonment	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
D50.9 Iron deficiency anaemia, unspecified	0.002	0.998	0.000
R50.0 Fever with chills	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
K11.2 Sialoadenitis	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
J38.4 Oedema of larynx	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.998	0.002
T70.8 Other effects of air pressure and water pressure	0.000	0.998	0.002
T70.4 Effects of high-pressure fluids	0.000	0.998	0.002
T70.2 Other and unspecified effects of high altitude	0.000	0.998	0.002
T70.1 Sinus barotrauma	0.000	0.998	0.002
T70.0 Otitic barotrauma	0.000	0.998	0.002
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.998	0.002
M87 Osteonecrosis	0.002	0.998	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.998	0.002
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
T75.1 Drowning and nonfatal submersion	0.000	0.998	0.002
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M70.56 Other bursitis of knee-Lower Leg	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
I63.8 Other cerebral infarction	0.000	0.998	0.002
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
M70 Soft tissue disorders related to use, overuse and pressure	0.002	0.998	0.000
M70.5 Other bursitis of knee	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.001	0.998	0.001
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.998	0.002
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.002
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
G72.3 Periodic paralysis	0.000	0.998	0.002
G72.2 Myopathy due to other toxic agents	0.000	0.998	0.002
G72.1 Alcoholic myopathy	0.000	0.998	0.002
M70.3 Other bursitis of elbow	0.002	0.998	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
M70.32 Other bursitis of elbow-Upper arm	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
S92.4 Fracture of great toe	0.000	0.998	0.002
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.998	0.002
K31.9 Disease of stomach and duodenum, unspecified	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
B00.9 Herpesviral infection, unspecified	0.000	0.998	0.002
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
G72.8 Other specified myopathies	0.000	0.998	0.002
M70.0 Chronic crepitant synovitis of hand and wrist	0.002	0.998	0.000
M87.3 Other secondary osteonecrosis	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.998	0.002
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
S22.5 Flail chest	0.000	0.998	0.002
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.002	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.002	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.002	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.002	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.002	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.002	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.002	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.002	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.002	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.002	0.998	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.002	0.998	0.000
M96.5 Postradiation scoliosis	0.002	0.998	0.000
M96.4 Postsurgical lordosis	0.002	0.998	0.000
M96.3 Postlaminectomy kyphosis	0.002	0.998	0.000
M96.2 Postradiation kyphosis	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
Z75.2 Other waiting period for investigation and treatment	0.000	0.998	0.002
L91.0 Keloid scar	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations