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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7743435
log Bayes Factor = 84.0467
Chromosome 6   position 31,101,202  (GRCh37) Explore rs7743435 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.999 0.001 0.000
L40.0 Psoriasis vulgaris
0.999 0.001 0.000
M07.3 Other psoriatic arthropathies
0.997 0.003 0.000
E10.9 Without complications
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.011 0.989
M07.30 Other psoriatic arthropathies (Multiple sites)
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.012 0.988
E10.3 With ophthalmic complications
0.000 0.022 0.978
E10.4 With neurological complications
0.000 0.028 0.972
E10.1 With ketoacidosis
0.000 0.044 0.956
E05.9 Thyrotoxicosis, unspecified
0.000 0.045 0.955
E10.2 With renal complications
0.000 0.105 0.895
L40.1 Generalised pustular psoriasis
0.886 0.114 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.885 0.115 0.000
E10.5 With peripheral circulatory complications
0.000 0.125 0.875
M07.34 Other psoriatic arthropathies (Hand)
0.861 0.139 0.000
E50-E64 Other nutritional deficiencies
0.000 0.145 0.855
M07.38 Other psoriatic arthropathies (Other)
0.853 0.147 0.000
L40.8 Other psoriasis
0.843 0.157 0.000
L40.4 Guttate psoriasis
0.825 0.175 0.000
E10.0 With coma
0.000 0.201 0.799
M07.36 Other psoriatic arthropathies (Lower leg)
0.799 0.201 0.000
E53 Deficiency of other B group vitamins
0.000 0.229 0.771
E10.6 With other specified complications
0.000 0.251 0.749
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.281 0.719
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E06 Thyroiditis
0.000 0.283 0.717
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.715 0.285 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.715 0.285 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.715 0.285 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.715 0.285 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.289 0.711
E12 Malnutrition-related diabetes mellitus
0.000 0.291 0.709
E65-E68 Obesity and other hyperalimentation
0.000 0.306 0.694
E10.8 With unspecified complications
0.000 0.307 0.693
E07 Other disorders of thyroid
0.000 0.307 0.692
E14 Unspecified diabetes mellitus
0.000 0.310 0.690
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.326 0.673
E55 Vitamin D deficiency
0.000 0.364 0.636
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.371 0.629
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.387 0.613
E63 Other nutritional deficiencies
0.000 0.387 0.613
E56 Other vitamin deficiencies
0.000 0.387 0.613
E51 Thiamine deficiency
0.000 0.387 0.613
E50 Vitamin A deficiency
0.000 0.387 0.613
E60 Dietary zinc deficiency
0.000 0.387 0.613
E59 Dietary selenium deficiency
0.000 0.387 0.613
E58 Dietary calcium deficiency
0.000 0.387 0.613
E54 Ascorbic acid deficiency
0.000 0.387 0.613
E52 Niacin deficiency [pellagra]
0.000 0.387 0.613
E03.8 Other specified hypothyroidism
0.000 0.391 0.609
E06.3 Autoimmune thyroiditis
0.000 0.440 0.560
E14.3 With ophthalmic complications
0.000 0.445 0.555
E53.9 Vitamin B deficiency, unspecified
0.000 0.447 0.553
E53.1 Pyridoxine deficiency
0.000 0.447 0.553
E53.0 Riboflavin deficiency
0.000 0.447 0.553
E61 Deficiency of other nutrient elements
0.000 0.448 0.552
E66 Obesity
0.000 0.454 0.546
E07.9 Disorder of thyroid, unspecified
0.000 0.463 0.537
E66.8 Other obesity
0.000 0.467 0.533
E16 Other disorders of pancreatic internal secretion
0.000 0.474 0.526
E13 Other specified diabetes mellitus
0.001 0.476 0.523
E15 Nondiabetic hypoglycaemic coma
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E06.5 Other chronic thyroiditis
0.000 0.486 0.514
E06.4 Drug-induced thyroiditis
0.000 0.486 0.514
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.486 0.514
E06.1 Subacute thyroiditis
0.000 0.486 0.514
E06.0 Acute thyroiditis
0.000 0.486 0.514
E12.9 Without complications
0.000 0.491 0.508
E12.8 With unspecified complications
0.000 0.491 0.508
E12.7 With multiple complications
0.000 0.491 0.508
E12.6 With other specified complications
0.000 0.491 0.508
E12.5 With peripheral circulatory complications
0.000 0.491 0.508
E12.4 With neurological complications
0.000 0.491 0.508
E12.3 With ophthalmic complications
0.000 0.491 0.508
E12.2 With renal complications
0.000 0.491 0.508
E12.1 With ketoacidosis
0.000 0.491 0.508
E12.0 With coma
0.000 0.491 0.508
E40-E46 Malnutrition
0.001 0.496 0.503
E67 Other hyperalimentation
0.000 0.502 0.498
E68 Sequelae of hyperalimentation
0.000 0.502 0.498
E07.1 Dyshormogenetic goitre
0.000 0.503 0.496
E07.0 Hypersecretion of calcitonin
0.000 0.503 0.496
K90 Intestinal malabsorption
0.000 0.504 0.496
E14.8 With unspecified complications
0.000 0.505 0.495
E14.7 With multiple complications
0.000 0.505 0.495
E14.6 With other specified complications
0.000 0.505 0.495
E14.2 Withrenal complications
0.000 0.505 0.495
E14.1 With ketoacidosis
0.000 0.505 0.495
E14.0 With coma
0.000 0.505 0.495
E14.4 With neurological complications
0.000 0.515 0.485
E20-E35 Disorders of other endocrine glands
0.000 0.520 0.480
E55.9 Vitamin D deficiency, unspecified
0.000 0.521 0.479
E14.5 With peripheral circulatory complications
0.000 0.525 0.475
E04 Other non-toxic goitre
0.000 0.536 0.464
E55.0 Rickets, active
0.000 0.544 0.456
E06.9 Thyroiditis, unspecified
0.000 0.546 0.454
M07 Psoriatic and enteropathic arthropathies
0.431 0.560 0.010
E50.9 Vitamin A deficiency, unspecified
0.000 0.560 0.440
E50.8 Other manifestations of vitamin A deficiency
0.000 0.560 0.440
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.560 0.440
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.560 0.440
E50.5 Vitamin A deficiency with night blindness
0.000 0.560 0.440
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.560 0.440
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.560 0.440
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.560 0.440
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.560 0.440
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.560 0.440
E51.9 Thiamine deficiency, unspecified
0.000 0.560 0.440
E51.8 Other manifestations of thiamine deficiency
0.000 0.560 0.440
E51.2 Wernicke's encephalopathy
0.000 0.560 0.440
E51.1 Beriberi
0.000 0.560 0.440
E56.9 Vitamin deficiency, unspecified
0.000 0.560 0.440
E56.8 Deficiency of other vitamins
0.000 0.560 0.440
E56.1 Deficiency of vitamin K
0.000 0.560 0.440
E56.0 Deficiency of vitamin E
0.000 0.560 0.440
E63.9 Nutritional deficiency, unspecified
0.000 0.560 0.440
E63.8 Other specified nutritional deficiencies
0.000 0.560 0.440
E63.1 Imbalance of constituents of food intake
0.000 0.560 0.440
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.560 0.440
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.560 0.440
E64.8 Sequelae of other nutritional deficiencies
0.000 0.560 0.440
E64.3 Sequelae of rickets
0.000 0.560 0.440
E64.2 Sequelae of vitamin C deficiency
0.000 0.560 0.440
E64.1 Sequelae of vitamin A deficiency
0.000 0.560 0.440
E64.0 Sequelae of protein-energy malnutrition
0.000 0.560 0.440
E14.9 Without complications
0.000 0.577 0.423
E27 Other disorders of adrenal gland
0.000 0.581 0.419
E65 Localised adiposity
0.000 0.584 0.416
E07.8 Other specified disorders of thyroid
0.000 0.584 0.415
E16.2 Hypoglycaemia, unspecified
0.000 0.587 0.413
E27.1 Primary adrenocortical insufficiency
0.000 0.591 0.409
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.597 0.402
E61.9 Deficiency of nutrient element, unspecified
0.000 0.604 0.396
E61.8 Deficiency of other specified nutrient elements
0.000 0.604 0.396
E61.7 Deficiency of multiple nutrient elements
0.000 0.604 0.396
E61.6 Vanadium deficiency
0.000 0.604 0.396
E61.5 Molybdenum deficiency
0.000 0.604 0.396
E61.4 Chromium deficiency
0.000 0.604 0.396
E61.3 Manganese deficiency
0.000 0.604 0.396
E61.2 Magnesium deficiency
0.000 0.604 0.396
E61.0 Copper deficiency
0.000 0.604 0.396
E66.1 Drug-induced obesity
0.000 0.609 0.391
E28 Ovarian dysfunction
0.000 0.613 0.387
E34 Other endocrine disorders
0.000 0.615 0.385
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.622 0.377
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.622 0.377
E16.4 Abnormal secretion of gastrin
0.000 0.622 0.377
E16.3 Increased secretion of glucagon
0.000 0.622 0.377
K90.9 Intestinal malabsorption, unspecified
0.000 0.623 0.377
K90.8 Other intestinal malabsorption
0.000 0.624 0.376
E13.8 With unspecified complications
0.001 0.624 0.375
E13.7 With multiple complications
0.001 0.624 0.375
E13.6 With other specified complications
0.001 0.624 0.375
E13.5 With peripheral circulatory complications
0.001 0.624 0.375
E13.4 With neurological complications
0.001 0.624 0.375
E13.3 With ophthalmic complications
0.001 0.624 0.375
E13.2 With renal complications
0.001 0.624 0.375
E13.1 With ketoacidosis
0.001 0.624 0.375
E13.0 With coma
0.001 0.624 0.375
E29 Testicular dysfunction
0.000 0.625 0.375
E16.1 Other hypoglycaemia
0.000 0.636 0.364
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.639 0.361
E45 Retarded development following protein-energy malnutrition
0.001 0.639 0.361
E43 Unspecified severe protein-energy malnutrition
0.001 0.639 0.361
E42 Marasmic kwashiorkor
0.001 0.639 0.361
E41 Nutritional marasmus
0.001 0.639 0.361
E40 Kwashiorkor
0.001 0.639 0.361
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.640 0.360
E67.8 Other specified hyperalimentation
0.000 0.643 0.357
E67.3 Hypervitaminosis D
0.000 0.643 0.357
E67.2 Megavitamin-B6 syndrome
0.000 0.643 0.357
E67.1 Hypercarotenaemia
0.000 0.643 0.357
E67.0 Hypervitaminosis A
0.000 0.643 0.357
K90.3 Pancreatic steatorrhoea
0.000 0.644 0.356
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.644 0.356
K90.1 Tropical sprue
0.000 0.644 0.356
E20 Hypoparathyroidism
0.000 0.649 0.351
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.656 0.344
E32 Diseases of thymus
0.000 0.656 0.344
E31 Polyglandular dysfunction
0.000 0.656 0.344
E30 Disorders of puberty, not elsewhere classified
0.000 0.656 0.344
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.661 0.338
E61.1 Iron deficiency
0.000 0.665 0.335
E04.8 Other specified non-toxic goitre
0.000 0.667 0.333
E28.3 Primary ovarian failure
0.000 0.668 0.332
E26 Hyperaldosteronism
0.000 0.671 0.329
E22 Hyperfunction of pituitary gland
0.000 0.671 0.329
M07.6 Other enteropathic arthropathies
0.309 0.684 0.007
M07.5 Arthropathy in ulcerative colitis
0.309 0.684 0.007
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.309 0.684 0.007
M07.2 Psoriatic spondylitis
0.309 0.684 0.007
M07.1 Arthritis mutilans
0.309 0.684 0.007
M07.0 Distal interphalangeal psoriatic arthropathy
0.309 0.684 0.007
E66.0 Obesity due to excess calories
0.000 0.688 0.312
E04.0 Non-toxic diffuse goitre
0.000 0.689 0.310
E04.9 Non-toxic goitre, unspecified
0.000 0.690 0.310
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.691 0.309
E34.8 Other specified endocrine disorders
0.000 0.691 0.309
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.698 0.302
E27.5 Adrenomedullary hyperfunction
0.000 0.700 0.300
E27.0 Other adrenocortical overactivity
0.000 0.700 0.300
E29.1 Testicular hypofunction
0.000 0.700 0.300
E04.1 Non-toxic single thyroid nodule
0.000 0.703 0.297
E27.8 Other specified disorders of adrenal gland
0.000 0.706 0.294
E27.2 Addisonian crisis
0.000 0.714 0.286
E25 Adrenogenital disorders
0.000 0.715 0.284
E34.9 Endocrine disorder, unspecified
0.000 0.717 0.283
E34.0 Carcinoid syndrome
0.000 0.719 0.281
E28.9 Ovarian dysfunction, unspecified
0.000 0.722 0.278
E28.8 Other ovarian dysfunction
0.000 0.722 0.278
E28.1 Androgen excess
0.000 0.722 0.278
E28.0 Oestrogen excess
0.000 0.722 0.278
E34.5 Androgen resistance syndrome
0.000 0.724 0.276
E34.4 Constitutional tall stature
0.000 0.724 0.276
E34.3 Short stature, not elsewhere classified
0.000 0.724 0.276
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.724 0.276
E34.1 Other hypersecretion of intestinal hormones
0.000 0.724 0.276
E29.9 Testicular dysfunction, unspecified
0.000 0.731 0.269
E29.8 Other testicular dysfunction
0.000 0.731 0.269
E29.0 Testicular hyperfunction
0.000 0.731 0.269
E44.1 Mild protein-energy malnutrition
0.001 0.741 0.259
E44.0 Moderate protein-energy malnutrition
0.001 0.741 0.259
E20.9 Hypoparathyroidism, unspecified
0.000 0.741 0.259
E28.2 Polycystic ovarian syndrome
0.000 0.743 0.257
E20.8 Other hypoparathyroidism
0.000 0.748 0.252
E20.1 Pseudohypoparathyroidism
0.000 0.748 0.252
E20.0 Idiopathic hypoparathyroidism
0.000 0.748 0.252
E22.1 Hyperprolactinaemia
0.000 0.748 0.252
E30.9 Disorder of puberty, unspecified
0.000 0.753 0.247
E30.8 Other disorders of puberty
0.000 0.753 0.247
E30.1 Precocious puberty
0.000 0.753 0.247
E30.0 Delayed puberty
0.000 0.753 0.247
E31.9 Polyglandular dysfunction, unspecified
0.000 0.753 0.247
E31.8 Other polyglandular dysfunction
0.000 0.753 0.247
E31.1 Polyglandular hyperfunction
0.000 0.753 0.247
E31.0 Autoimmune polyglandular failure
0.000 0.753 0.247
E32.9 Disease of thymus, unspecified
0.000 0.753 0.247
E32.8 Other diseases of thymus
0.000 0.753 0.247
E32.1 Abscess of thymus
0.000 0.753 0.247
E32.0 Persistent hyperplasia of thymus
0.000 0.753 0.247
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.753 0.247
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.753 0.247
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.753 0.247
E22.0 Acromegaly and pituitary gigantism
0.000 0.753 0.247
E04.2 Non-toxic multinodular goitre
0.000 0.755 0.245
E26.9 Hyperaldosteronism, unspecified
0.000 0.764 0.236
E26.8 Other hyperaldosteronism
0.000 0.764 0.236
E26.1 Secondary hyperaldosteronism
0.000 0.764 0.236
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.764 0.236
E22.8 Other hyperfunction of pituitary gland
0.000 0.764 0.236
M35.3 Polymyalgia rheumatica
0.000 0.769 0.231
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.222 0.773 0.005
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.222 0.773 0.005
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.222 0.773 0.005
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.222 0.773 0.005
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.222 0.773 0.005
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.222 0.773 0.005
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.222 0.773 0.005
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.222 0.773 0.005
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.222 0.773 0.005
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.222 0.773 0.005
M07.19 Arthritis mutilans (Site unspecified)
0.222 0.773 0.005
M07.18 Arthritis mutilans (Other)
0.222 0.773 0.005
M07.17 Arthritis mutilans (Ankle and foot)
0.222 0.773 0.005
M07.16 Arthritis mutilans (Lower leg)
0.222 0.773 0.005
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.222 0.773 0.005
M07.14 Arthritis mutilans (Hand)
0.222 0.773 0.005
M07.13 Arthritis mutilans (Forearm)
0.222 0.773 0.005
M07.12 Arthritis mutilans (Upper arm)
0.222 0.773 0.005
M07.11 Arthritis mutilans (Shoulder region)
0.222 0.773 0.005
M07.10 Arthritis mutilans (Multiple sites)
0.222 0.773 0.005
M07.29 Psoriatic spondylitis (Site unspecified)
0.222 0.773 0.005
M07.28 Psoriatic spondylitis (Other)
0.222 0.773 0.005
M07.27 Psoriatic spondylitis (Ankle and foot)
0.222 0.773 0.005
M07.26 Psoriatic spondylitis (Lower leg)
0.222 0.773 0.005
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.222 0.773 0.005
M07.24 Psoriatic spondylitis (Hand)
0.222 0.773 0.005
M07.23 Psoriatic spondylitis (Forearm)
0.222 0.773 0.005
M07.22 Psoriatic spondylitis (Upper arm)
0.222 0.773 0.005
M07.21 Psoriatic spondylitis (Shoulder region)
0.222 0.773 0.005
M07.20 Psoriatic spondylitis (Multiple sites)
0.222 0.773 0.005
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.222 0.773 0.005
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.222 0.773 0.005
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.222 0.773 0.005
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.222 0.773 0.005
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.222 0.773 0.005
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.222 0.773 0.005
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.222 0.773 0.005
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.222 0.773 0.005
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.222 0.773 0.005
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.222 0.773 0.005
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.222 0.773 0.005
M07.58 Arthropathy in ulcerative colitis (Other)
0.222 0.773 0.005
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.222 0.773 0.005
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.222 0.773 0.005
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.222 0.773 0.005
M07.54 Arthropathy in ulcerative colitis (Hand)
0.222 0.773 0.005
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.222 0.773 0.005
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.222 0.773 0.005
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.222 0.773 0.005
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.222 0.773 0.005
M07.69 Other enteropathic arthropathies (Site unspecified)
0.222 0.773 0.005
M07.68 Other enteropathic arthropathies (Other)
0.222 0.773 0.005
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.222 0.773 0.005
M07.66 Other enteropathic arthropathies (Lower leg)
0.222 0.773 0.005
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.222 0.773 0.005
M07.64 Other enteropathic arthropathies (Hand)
0.222 0.773 0.005
M07.63 Other enteropathic arthropathies (Forearm)
0.222 0.773 0.005
M07.62 Other enteropathic arthropathies (Upper arm)
0.222 0.773 0.005
M07.61 Other enteropathic arthropathies (Shoulder region)
0.222 0.773 0.005
M07.60 Other enteropathic arthropathies (Multiple sites)
0.222 0.773 0.005
E24 Cushing's syndrome
0.001 0.775 0.224
E26.0 Primary hyperaldosteronism
0.000 0.779 0.221
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.787 0.212
E25.9 Adrenogenital disorder, unspecified
0.000 0.796 0.204
E25.8 Other adrenogenital disorders
0.000 0.796 0.204
M35 Other systemic involvement of connective tissue
0.000 0.802 0.198
L40-L45 Papulosquamous disorders
0.197 0.803 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.805 0.195
E13.9 Without complications
0.001 0.809 0.189
M35.0 Sicca syndrome [Sjogren]
0.000 0.812 0.188
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.820 0.180
E27.9 Disorder of adrenal gland, unspecified
0.001 0.824 0.176
M35.1 Other overlap syndromes
0.000 0.833 0.167
E24.8 Other Cushing's syndrome
0.001 0.839 0.161
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.839 0.161
E24.3 Ectopic ACTH syndrome
0.001 0.839 0.161
E24.2 Drug-induced Cushing's syndrome
0.001 0.839 0.161
E24.1 Nelson's syndrome
0.001 0.839 0.161
E46 Unspecified protein-energy malnutrition
0.002 0.844 0.155
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.850 0.150
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.855 0.144
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.858 0.142
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.858 0.142
M35.5 Multifocal fibrosclerosis
0.000 0.858 0.142
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.858 0.142
M35.2 Behcet's disease
0.000 0.858 0.142
L44 Other papulosquamous disorders
0.141 0.858 0.000
L41 Parapsoriasis
0.141 0.858 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.141 0.858 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.860 0.140
E23.1 Drug-induced hypopituitarism
0.000 0.860 0.140
M35.7 Hypermobility syndrome
0.000 0.861 0.138
E23.2 Diabetes insipidus
0.000 0.864 0.135
M35.8 Other specified systemic involvement of connective tissue
0.000 0.866 0.133
E23.6 Other disorders of pituitary gland
0.000 0.871 0.129
E23.7 Disorder of pituitary gland, unspecified
0.000 0.875 0.124
L42 Pityriasis rosea
0.121 0.879 0.000
E24.9 Cushing's syndrome, unspecified
0.001 0.879 0.121
J47 Bronchiectasis
0.000 0.880 0.120
E24.0 Pituitary-dependent Cushing's disease
0.001 0.887 0.112
E11 Non-insulin-dependent diabetes mellitus
0.000 0.889 0.111
E21.4 Other specified disorders of parathyroid gland
0.000 0.892 0.107
E21.2 Other hyperparathyroidism
0.000 0.892 0.107
E11.3 With ophthalmic complications
0.000 0.895 0.105
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.898 0.102
L41.9 Parapsoriasis, unspecified
0.102 0.898 0.000
L41.8 Other parapsoriasis
0.102 0.898 0.000
L41.5 Retiform parapsoriasis
0.102 0.898 0.000
L41.4 Large plaque parapsoriasis
0.102 0.898 0.000
L41.3 Small plaque parapsoriasis
0.102 0.898 0.000
L41.2 Lymphomatoid papulosis
0.102 0.898 0.000
L41.1 Pityriasis lichenoides chronica
0.102 0.898 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.102 0.898 0.000
L44.9 Papulosquamous disorder, unspecified
0.102 0.898 0.000
L44.8 Other specified papulosquamous disorders
0.102 0.898 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.102 0.898 0.000
L44.3 Lichen ruber moniliformis
0.102 0.898 0.000
L44.2 Lichen striatus
0.102 0.898 0.000
L44.1 Lichen nitidus
0.102 0.898 0.000
L44.0 Pityriasis rubra pilaris
0.102 0.898 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.904 0.096
M06.9 Rheumatoid arthritis, unspecified
0.000 0.905 0.095
E21.0 Primary hyperparathyroidism
0.000 0.906 0.094
E70-E90 Metabolic disorders
0.000 0.909 0.091
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.910 0.089
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.913 0.087
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.914 0.085
E11.8 With unspecified complications
0.000 0.918 0.082
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.918 0.082
E73 Lactose intolerance
0.000 0.919 0.081
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.919 0.081
E11.7 With multiple complications
0.000 0.920 0.080
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.921 0.079
L43 Lichen planus
0.078 0.922 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.000 0.923 0.077
R41.0 Disorientation, unspecified
0.000 0.923 0.077
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.000 0.923 0.077
E85 Amyloidosis
0.000 0.924 0.075
E73.9 Lactose intolerance, unspecified
0.000 0.925 0.075
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.926 0.074
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.926 0.074
E23.0 Hypopituitarism
0.000 0.927 0.073
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.927 0.073
R41.3 Other amnesia
0.000 0.927 0.073
E11.5 With peripheral circulatory complications
0.000 0.927 0.073
E11.0 With coma
0.000 0.929 0.070
Z93.2 Ileostomy status
0.000 0.930 0.070
E83 Disorders of mineral metabolism
0.000 0.931 0.069
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.000 0.932 0.068
E21.3 Hyperparathyroidism, unspecified
0.000 0.932 0.067
E74 Other disorders of carbohydrate metabolism
0.000 0.933 0.067
R41.2 Retrograde amnesia
0.000 0.933 0.066
E84 Cystic fibrosis
0.000 0.935 0.065
E79 Disorders of purine and pyrimidine metabolism
0.000 0.935 0.065
E77 Disorders of glycoprotein metabolism
0.000 0.935 0.065
E76 Disorders of glycosaminoglycan metabolism
0.000 0.935 0.065
E72 Other disorders of amino-acid metabolism
0.000 0.935 0.065
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.935 0.065
E70 Disorders of aromatic amino-acid metabolism
0.000 0.935 0.065
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.935 0.065
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.935 0.065
E11.1 With ketoacidosis
0.000 0.937 0.063
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.938 0.062
E83.4 Disorders of magnesium metabolism
0.000 0.939 0.061
E85.9 Amyloidosis, unspecified
0.000 0.939 0.061
E83.3 Disorders of phosphorus metabolism
0.000 0.940 0.060
E85.4 Organ-limited amyloidosis
0.000 0.940 0.060
N20.1 Calculus of ureter
0.059 0.941 0.000
E73.8 Other lactose intolerance
0.000 0.941 0.058
E73.1 Secondary lactase deficiency
0.000 0.941 0.058
E73.0 Congenital lactase deficiency
0.000 0.941 0.058
L43.3 Subacute (active) lichen planus
0.056 0.944 0.000
L43.2 Lichenoid drug reaction
0.056 0.944 0.000
L43.1 Bullous lichen planus
0.056 0.944 0.000
L43.0 Hypertrophic lichen planus
0.056 0.944 0.000
E11.6 With other specified complications
0.000 0.944 0.055
M06 Other rheumatoid arthritis
0.007 0.944 0.049
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.944 0.056
E85.8 Other amyloidosis
0.000 0.946 0.054
E85.3 Secondary systemic amyloidosis
0.000 0.946 0.054
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.946 0.054
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.946 0.054
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.946 0.054
N20.0 Calculus of kidney
0.053 0.947 0.000
N20 Calculus of kidney and ureter
0.053 0.947 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.000 0.948 0.052
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.000 0.948 0.052
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.000 0.949 0.051
R41.1 Anterograde amnesia
0.000 0.949 0.051
K90-K93 Other diseases of the digestive system
0.000 0.950 0.050
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.950 0.050
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.950 0.050
E83.8 Other disorders of mineral metabolism
0.000 0.950 0.050
E83.2 Disorders of zinc metabolism
0.000 0.950 0.050
E83.0 Disorders of copper metabolism
0.000 0.950 0.050
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.952 0.048
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.952 0.048
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.952 0.048
E74.2 Disorders of galactose metabolism
0.000 0.952 0.048
E74.1 Disorders of fructose metabolism
0.000 0.952 0.048
E74.0 Glycogen storage disease
0.000 0.952 0.048
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.953 0.047
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.953 0.047
E70.3 Albinism
0.000 0.953 0.047
E70.2 Disorders of tyrosine metabolism
0.000 0.953 0.047
E70.1 Other hyperphenylalaninaemias
0.000 0.953 0.047
E70.0 Classical phenylketonuria
0.000 0.953 0.047
E71.3 Disorders of fatty-acid metabolism
0.000 0.953 0.047
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.953 0.047
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.953 0.047
E71.0 Maple-syrup-urine disease
0.000 0.953 0.047
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.953 0.047
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.953 0.047
E72.5 Disorders of glycine metabolism
0.000 0.953 0.047
E72.4 Disorders of ornithine metabolism
0.000 0.953 0.047
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.953 0.047

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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