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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7744001
log Bayes Factor = 89.8738
Chromosome 6   position 32,626,086  (GRCh37) Explore rs7744001 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
N48 Other disorders of penis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
N48.6 Balanitis xerotica obliterans
0.999 0.001 0.000
E10.4 With neurological complications
0.000 0.001 0.999
H36.0 Diabetic retinopathy
0.000 0.002 0.998
E10.2 With renal complications
0.000 0.004 0.996
N40-N51 Diseases of male genital organs
0.995 0.005 0.000
E14 Unspecified diabetes mellitus
0.000 0.016 0.984
E10.5 With peripheral circulatory complications
0.000 0.022 0.978
N48.0 Leukoplakia of penis
0.977 0.023 0.000
N48.1 Balanoposthitis
0.961 0.039 0.000
E14.3 With ophthalmic complications
0.000 0.058 0.942
E50-E64 Other nutritional deficiencies
0.000 0.072 0.928
D07.1 Vulva
0.916 0.084 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.910 0.090 0.000
E55 Vitamin D deficiency
0.000 0.092 0.908
E83.1 Disorders of iron metabolism
0.000 0.093 0.907
D00-D09 In situ neoplasms
0.905 0.095 0.000
E83 Disorders of mineral metabolism
0.000 0.095 0.905
E70-E90 Metabolic disorders
0.000 0.096 0.904
N48.2 Other inflammatory disorders of penis
0.896 0.104 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.106 0.894
D06 Carcinoma in situ of cervix uteri
0.890 0.110 0.000
N90.4 Leukoplakia of vulva
0.878 0.122 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.875 0.125 0.000
D06.9 Cervix, unspecified
0.871 0.129 0.000
D04 Carcinoma in situ of skin
0.853 0.147 0.000
N48.8 Other specified disorders of penis
0.846 0.154 0.000
N44 Torsion of testis
0.838 0.162 0.000
N45 Orchitis and epididymitis
0.837 0.163 0.000
D07.4 Penis
0.835 0.165 0.000
E10.0 With coma
0.000 0.167 0.833
N90.7 Vulvar cyst
0.830 0.170 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.178 0.822
N48.5 Ulcer of penis
0.820 0.180 0.000
E10.8 With unspecified complications
0.000 0.186 0.814
E40-E46 Malnutrition
0.000 0.196 0.804
E14.8 With unspecified complications
0.000 0.198 0.802
E14.9 Without complications
0.000 0.200 0.800
N48.9 Disorder of penis, unspecified
0.799 0.201 0.000
D04.7 Skin of lower limb, including hip
0.798 0.202 0.000
N90.3 Dysplasia of vulva, unspecified
0.798 0.202 0.000
D03 Melanoma in situ
0.794 0.206 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.788 0.212 0.000
D04.9 Skin, unspecified
0.778 0.222 0.000
N48.3 Priapism
0.777 0.223 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.771 0.229 0.000
E14.6 With other specified complications
0.000 0.230 0.770
D01 Carcinoma in situ of other and unspecified digestive organs
0.768 0.232 0.000
E10.6 With other specified complications
0.000 0.237 0.763
D03.2 Melanoma in situ of ear and external auricular canal
0.761 0.239 0.000
N90.1 Moderate vulvar dysplasia
0.760 0.240 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.244 0.756
E14.5 With peripheral circulatory complications
0.000 0.253 0.747
N90.6 Hypertrophy of vulva
0.740 0.260 0.000
D09 Carcinoma in situ of other and unspecified sites
0.733 0.267 0.000
E27 Other disorders of adrenal gland
0.000 0.271 0.729
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.272 0.728
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.727 0.273 0.000
E14.2 Withrenal complications
0.000 0.275 0.725
E14.1 With ketoacidosis
0.000 0.277 0.722
D06.1 Exocervix
0.719 0.281 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.290 0.710
E14.7 With multiple complications
0.000 0.295 0.705
E14.0 With coma
0.000 0.295 0.705
E87.7 Fluid overload
0.000 0.295 0.705
N51 Disorders of male genital organs in diseases classified elsewhere
0.703 0.297 0.000
D04.4 Skin of scalp and neck
0.701 0.299 0.000
E51 Thiamine deficiency
0.000 0.301 0.699
N48.4 Impotence of organic origin
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.303 0.696
D07.2 Vagina
0.693 0.307 0.000
D06.0 Endocervix
0.685 0.315 0.000
N42 Other disorders of prostate
0.679 0.321 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.678 0.322 0.000
E84 Cystic fibrosis
0.000 0.327 0.673
D01.3 Anus and anal canal
0.671 0.329 0.000
E14.4 With neurological complications
0.000 0.333 0.667
E73 Lactose intolerance
0.000 0.333 0.667
E27.8 Other specified disorders of adrenal gland
0.000 0.334 0.666
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.335 0.665
E63 Other nutritional deficiencies
0.000 0.335 0.665
E50 Vitamin A deficiency
0.000 0.335 0.665
E60 Dietary zinc deficiency
0.000 0.335 0.665
E59 Dietary selenium deficiency
0.000 0.335 0.665
E54 Ascorbic acid deficiency
0.000 0.335 0.665
E52 Niacin deficiency [pellagra]
0.000 0.335 0.665
E11 Non-insulin-dependent diabetes mellitus
0.000 0.336 0.664
E46 Unspecified protein-energy malnutrition
0.000 0.337 0.663
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.662 0.338 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.657 0.343 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.343 0.657
D07.6 Other and unspecified male genital organs
0.653 0.347 0.000
D07.3 Other and unspecified female genital organs
0.653 0.347 0.000
D07.0 Endometrium
0.653 0.347 0.000
E55.0 Rickets, active
0.000 0.349 0.651
E83.8 Other disorders of mineral metabolism
0.000 0.351 0.648
E83.2 Disorders of zinc metabolism
0.000 0.351 0.648
E83.0 Disorders of copper metabolism
0.000 0.351 0.648
N90.0 Mild vulvar dysplasia
0.649 0.351 0.000
E77 Disorders of glycoprotein metabolism
0.000 0.352 0.648
E76 Disorders of glycosaminoglycan metabolism
0.000 0.352 0.648
E72 Other disorders of amino-acid metabolism
0.000 0.352 0.648
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.352 0.648
E70 Disorders of aromatic amino-acid metabolism
0.000 0.352 0.648
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.352 0.648
D09.1 Other and unspecified urinary organs
0.645 0.355 0.000
D06.7 Other parts of cervix
0.638 0.362 0.000
D04.3 Skin of other and unspecified parts of face
0.630 0.370 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.372 0.628
E88 Other metabolic disorders
0.000 0.372 0.628
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.627 0.372 0.000
D03.8 Melanoma in situ of other sites
0.624 0.376 0.000
N46 Male infertility
0.621 0.379 0.000
E56 Other vitamin deficiencies
0.000 0.379 0.620
E34 Other endocrine disorders
0.000 0.381 0.619
D04.8 Skin of other sites
0.612 0.388 0.000
D04.0 Skin of lip
0.612 0.388 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.388 0.612
E58 Dietary calcium deficiency
0.000 0.395 0.605
N41 Inflammatory diseases of prostate
0.603 0.397 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.398 0.602
D03.7 Melanoma in situ of lower limb, including hip
0.598 0.402 0.000
J45 Asthma
0.595 0.405 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.594 0.406 0.000
E11.3 With ophthalmic complications
0.000 0.413 0.587
E16.1 Other hypoglycaemia
0.000 0.413 0.587
E28 Ovarian dysfunction
0.000 0.413 0.587
N42.9 Disorder of prostate, unspecified
0.582 0.418 0.000
D04.5 Skin of trunk
0.579 0.421 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.424 0.576
E45 Retarded development following protein-energy malnutrition
0.000 0.424 0.576
E43 Unspecified severe protein-energy malnutrition
0.000 0.424 0.576
E42 Marasmic kwashiorkor
0.000 0.424 0.576
E41 Nutritional marasmus
0.000 0.424 0.576
E40 Kwashiorkor
0.000 0.424 0.576
E11.4 With neurological complications
0.000 0.426 0.574
D03.9 Melanoma in situ, unspecified
0.569 0.431 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.569 0.431 0.000
D03.0 Melanoma in situ of lip
0.569 0.431 0.000
E53 Deficiency of other B group vitamins
0.000 0.431 0.569
E03 Other hypothyroidism
0.367 0.435 0.198
D01.9 Digestive organ, unspecified
0.551 0.449 0.000
D01.7 Other specified digestive organs
0.551 0.449 0.000
D01.5 Liver, gallbladder and bile ducts
0.551 0.449 0.000
D01.4 Other and unspecified parts of intestine
0.551 0.449 0.000
D01.2 Rectum
0.551 0.449 0.000
D01.1 Rectosigmoid junction
0.551 0.449 0.000
D03.5 Melanoma in situ of trunk
0.548 0.452 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.452 0.548
D01.0 Colon
0.547 0.452 0.000
D04.1 Skin of eyelid, including canthus
0.547 0.453 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.458 0.542
E32 Diseases of thymus
0.000 0.458 0.542
E31 Polyglandular dysfunction
0.000 0.458 0.542
E30 Disorders of puberty, not elsewhere classified
0.000 0.458 0.542
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.459 0.541
E23.7 Disorder of pituitary gland, unspecified
0.000 0.459 0.541
E00-E07 Disorders of thyroid gland
0.017 0.463 0.520
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.464 0.536
E51.2 Wernicke's encephalopathy
0.000 0.465 0.535
N42.2 Atrophy of prostate
0.533 0.467 0.000
E61 Deficiency of other nutrient elements
0.000 0.469 0.531
D09.9 Carcinoma in situ, unspecified
0.526 0.474 0.000
D09.7 Carcinoma in situ of other specified sites
0.526 0.474 0.000
D09.3 Thyroid and other endocrine glands
0.526 0.474 0.000
D09.2 Eye
0.526 0.474 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.476 0.524
E11.1 With ketoacidosis
0.000 0.477 0.523
E27.5 Adrenomedullary hyperfunction
0.000 0.477 0.523
E27.0 Other adrenocortical overactivity
0.000 0.477 0.523
E27.9 Disorder of adrenal gland, unspecified
0.000 0.477 0.523
E87.4 Mixed disorder of acid-base balance
0.000 0.478 0.522
E89.0 Postprocedural hypothyroidism
0.000 0.478 0.522
E74 Other disorders of carbohydrate metabolism
0.000 0.483 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E83.5 Disorders of calcium metabolism
0.000 0.486 0.514
D00.0 Lip, oral cavity and pharynx
0.508 0.492 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.493 0.507
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.504 0.496 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.504 0.496 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.504 0.496 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.499 0.501
E51.8 Other manifestations of thiamine deficiency
0.000 0.499 0.501
E51.1 Beriberi
0.000 0.499 0.501
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.500 0.499
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.500 0.499
E79.1 Lesch-Nyhan syndrome
0.000 0.500 0.499
E34.9 Endocrine disorder, unspecified
0.000 0.501 0.499
N42.1 Congestion and haemorrhage of prostate
0.498 0.502 0.000
E22 Hyperfunction of pituitary gland
0.000 0.502 0.497
E73.9 Lactose intolerance, unspecified
0.000 0.504 0.496
E25 Adrenogenital disorders
0.000 0.504 0.495
N51.2 Balanitis in diseases classified elsewhere
0.493 0.507 0.000
E11.5 With peripheral circulatory complications
0.000 0.509 0.491
E89.3 Postprocedural hypopituitarism
0.000 0.511 0.488
E20 Hypoparathyroidism
0.000 0.513 0.487
J45.0 Predominantly allergic asthma
0.487 0.513 0.000
N42.3 Dysplasia of prostate
0.487 0.513 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.486 0.514 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.486 0.514 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.486 0.514 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.485 0.515 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.517 0.483
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.517 0.483
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.517 0.483
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.518 0.482
D02.0 Larynx
0.480 0.520 0.000
D04.2 Skin of ear and external auricular canal
0.480 0.520 0.000
E26 Hyperaldosteronism
0.000 0.521 0.479
E73.8 Other lactose intolerance
0.000 0.522 0.478
E73.1 Secondary lactase deficiency
0.000 0.522 0.478
E73.0 Congenital lactase deficiency
0.000 0.522 0.478
E50.9 Vitamin A deficiency, unspecified
0.000 0.523 0.477
E50.8 Other manifestations of vitamin A deficiency
0.000 0.523 0.477
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.523 0.477
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.523 0.477
E50.5 Vitamin A deficiency with night blindness
0.000 0.523 0.477
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.523 0.477
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.523 0.477
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.523 0.477
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.523 0.477
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.523 0.477
E63.9 Nutritional deficiency, unspecified
0.000 0.523 0.477
E63.8 Other specified nutritional deficiencies
0.000 0.523 0.477
E63.1 Imbalance of constituents of food intake
0.000 0.523 0.477
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.523 0.477
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.523 0.477
E64.8 Sequelae of other nutritional deficiencies
0.000 0.523 0.477
E64.3 Sequelae of rickets
0.000 0.523 0.477
E64.2 Sequelae of vitamin C deficiency
0.000 0.523 0.477
E64.1 Sequelae of vitamin A deficiency
0.000 0.523 0.477
E64.0 Sequelae of protein-energy malnutrition
0.000 0.523 0.477
E29 Testicular dysfunction
0.000 0.524 0.476
E34.8 Other specified endocrine disorders
0.000 0.524 0.476
E11.7 With multiple complications
0.000 0.524 0.476
E23.6 Other disorders of pituitary gland
0.000 0.524 0.476
D00.2 Stomach
0.475 0.525 0.000
D02.4 Respiratory system, unspecified
0.471 0.529 0.000
D02.3 Other parts of respiratory system
0.471 0.529 0.000
D02.2 Bronchus and lung
0.471 0.529 0.000
D02.1 Trachea
0.471 0.529 0.000
K90 Intestinal malabsorption
0.000 0.529 0.471
N49.8 Inflammatory disorders of other specified male genital organs
0.471 0.529 0.000
N49.2 Inflammatory disorders of scrotum
0.468 0.532 0.000
N41.1 Chronic prostatitis
0.467 0.533 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.535 0.465
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.535 0.465
E70.3 Albinism
0.000 0.535 0.465
E70.2 Disorders of tyrosine metabolism
0.000 0.535 0.465
E70.1 Other hyperphenylalaninaemias
0.000 0.535 0.465
E70.0 Classical phenylketonuria
0.000 0.535 0.465
E71.3 Disorders of fatty-acid metabolism
0.000 0.535 0.465
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.535 0.465
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.535 0.465
E71.0 Maple-syrup-urine disease
0.000 0.535 0.465
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.535 0.465
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.535 0.465
E72.5 Disorders of glycine metabolism
0.000 0.535 0.465
E72.4 Disorders of ornithine metabolism
0.000 0.535 0.465
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.535 0.465
E72.2 Disorders of urea cycle metabolism
0.000 0.535 0.465
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.535 0.465
E72.0 Disorders of amino-acid transport
0.000 0.535 0.465
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.535 0.465
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.535 0.465
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.535 0.465
E76.2 Other mucopolysaccharidoses
0.000 0.535 0.465
E76.1 Mucopolysaccharidosis, type II
0.000 0.535 0.465
E76.0 Mucopolysaccharidosis, type I
0.000 0.535 0.465
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.535 0.465
E77.8 Other disorders of glycoprotein metabolism
0.000 0.535 0.465
E77.1 Defects in glycoprotein degradation
0.000 0.535 0.465
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.535 0.465
E11.8 With unspecified complications
0.000 0.539 0.461
E89.4 Postprocedural ovarian failure
0.000 0.544 0.456
E28.2 Polycystic ovarian syndrome
0.000 0.544 0.455
D04.6 Skin of upper limb, including shoulder
0.454 0.546 0.000
E23.0 Hypopituitarism
0.000 0.548 0.452
D00.1 Oesophagus
0.451 0.548 0.000
E88.8 Other specified metabolic disorders
0.000 0.550 0.450
J45.8 Mixed asthma
0.450 0.550 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.551 0.449
E87.2 Acidosis
0.000 0.552 0.448
D03.3 Melanoma in situ of other and unspecified parts of face
0.448 0.552 0.000
D09.0 Bladder
0.446 0.554 0.000
J45.1 Nonallergic asthma
0.446 0.554 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.555 0.445
E56.8 Deficiency of other vitamins
0.000 0.555 0.445
E56.0 Deficiency of vitamin E
0.000 0.555 0.445
E34.5 Androgen resistance syndrome
0.000 0.556 0.444
E34.4 Constitutional tall stature
0.000 0.556 0.444
E34.3 Short stature, not elsewhere classified
0.000 0.556 0.444
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.556 0.444
E34.1 Other hypersecretion of intestinal hormones
0.000 0.556 0.444
N90.5 Atrophy of vulva
0.444 0.556 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.557 0.443
E34.0 Carcinoid syndrome
0.000 0.558 0.442
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.561 0.439
E23.1 Drug-induced hypopituitarism
0.000 0.561 0.439
D03.4 Melanoma in situ of scalp and neck
0.438 0.562 0.000
N41.8 Other inflammatory diseases of prostate
0.435 0.565 0.000
E28.3 Primary ovarian failure
0.000 0.567 0.433
N41.3 Prostatocystitis
0.432 0.568 0.000
N41.2 Abscess of prostate
0.432 0.568 0.000
E13 Other specified diabetes mellitus
0.001 0.568 0.432
E53.9 Vitamin B deficiency, unspecified
0.000 0.568 0.432
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.568 0.432
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.568 0.432
E89.1 Postprocedural hypoinsulinaemia
0.000 0.568 0.432
E87.5 Hyperkalaemia
0.000 0.573 0.427
E11.0 With coma
0.000 0.578 0.422
E28.9 Ovarian dysfunction, unspecified
0.000 0.579 0.421
E28.8 Other ovarian dysfunction
0.000 0.579 0.421
E28.1 Androgen excess
0.000 0.579 0.421
E28.0 Oestrogen excess
0.000 0.579 0.421
E11.2 With renal complications
0.000 0.586 0.414
E44.1 Mild protein-energy malnutrition
0.000 0.587 0.413
E44.0 Moderate protein-energy malnutrition
0.000 0.587 0.413
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.588 0.412
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.590 0.410
E53.1 Pyridoxine deficiency
0.000 0.592 0.408
E53.0 Riboflavin deficiency
0.000 0.592 0.408
E27.2 Addisonian crisis
0.000 0.594 0.405
E03.5 Myxoedema coma
0.263 0.595 0.142
E03.4 Atrophy of thyroid (acquired)
0.263 0.595 0.142
E03.3 Postinfectious hypothyroidism
0.263 0.595 0.142
E22.0 Acromegaly and pituitary gigantism
0.000 0.595 0.405
E61.2 Magnesium deficiency
0.000 0.599 0.401
E56.1 Deficiency of vitamin K
0.000 0.600 0.400
L90.0 Lichen sclerosus et atrophicus
0.400 0.600 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.257 0.602 0.141
N41.0 Acute prostatitis
0.398 0.602 0.000
N43 Hydrocele and spermatocele
0.393 0.607 0.000
E03.1 Congenital hypothyroidism without goitre
0.246 0.608 0.145
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.610 0.390
E30.9 Disorder of puberty, unspecified
0.000 0.611 0.389
E30.8 Other disorders of puberty
0.000 0.611 0.389
E30.1 Precocious puberty
0.000 0.611 0.389
E30.0 Delayed puberty
0.000 0.611 0.389
E31.9 Polyglandular dysfunction, unspecified
0.000 0.611 0.389
E31.8 Other polyglandular dysfunction
0.000 0.611 0.389
E31.1 Polyglandular hyperfunction
0.000 0.611 0.389
E31.0 Autoimmune polyglandular failure
0.000 0.611 0.389
E32.9 Disease of thymus, unspecified
0.000 0.611 0.389
E32.8 Other diseases of thymus
0.000 0.611 0.389
E32.1 Abscess of thymus
0.000 0.611 0.389
E32.0 Persistent hyperplasia of thymus
0.000 0.611 0.389
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.611 0.389
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.611 0.389
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.611 0.389
E02 Subclinical iodine-deficiency hypothyroidism
0.011 0.611 0.378
E05 Thyrotoxicosis [hyperthyroidism]
0.004 0.612 0.384
E87.0 Hyperosmolality and hypernatraemia
0.000 0.615 0.385
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.012 0.615 0.373
E00 Congenital iodine-deficiency syndrome
0.012 0.615 0.373
N42.8 Other specified disorders of prostate
0.384 0.616 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.247 0.619 0.135
E61.9 Deficiency of nutrient element, unspecified
0.000 0.619 0.380
E61.8 Deficiency of other specified nutrient elements
0.000 0.619 0.380
E61.7 Deficiency of multiple nutrient elements
0.000 0.619 0.380
E61.6 Vanadium deficiency
0.000 0.619 0.380
E61.5 Molybdenum deficiency
0.000 0.619 0.380
E61.4 Chromium deficiency
0.000 0.619 0.380
E61.3 Manganese deficiency
0.000 0.619 0.380
E61.0 Copper deficiency
0.000 0.619 0.380
E89.5 Postprocedural testicular hypofunction
0.000 0.621 0.379
E07 Other disorders of thyroid
0.011 0.622 0.367
E65-E68 Obesity and other hyperalimentation
0.000 0.624 0.376
E75.6 Lipid storage disorder, unspecified
0.000 0.624 0.375
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.624 0.375
E75.3 Sphingolipidosis, unspecified
0.000 0.624 0.375
E75.1 Other gangliosidosis
0.000 0.624 0.375
E75.0 GM2 gangliosidosis
0.000 0.624 0.375
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.624 0.375
C21.0 Anus, unspecified
0.374 0.626 0.000
E03.8 Other specified hypothyroidism
0.257 0.626 0.117
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.629 0.370
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.629 0.370
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.629 0.370
E74.2 Disorders of galactose metabolism
0.000 0.629 0.370
E74.1 Disorders of fructose metabolism
0.000 0.629 0.370
E74.0 Glycogen storage disease
0.000 0.629 0.370
E11.6 With other specified complications
0.000 0.630 0.369
E88.3 Tumour lysis syndrome
0.000 0.633 0.367
E87.3 Alkalosis
0.000 0.633 0.367
C21.1 Anal canal
0.366 0.634 0.000
C21 Malignant neoplasm of anus and anal canal
0.365 0.635 0.000
E85 Amyloidosis
0.001 0.640 0.360
E83.3 Disorders of phosphorus metabolism
0.000 0.643 0.357
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.643 0.357
E22.8 Other hyperfunction of pituitary gland
0.000 0.643 0.357
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.643 0.357
E25.9 Adrenogenital disorder, unspecified
0.000 0.644 0.355
E25.8 Other adrenogenital disorders
0.000 0.644 0.355
E20.8 Other hypoparathyroidism
0.000 0.650 0.349
E20.1 Pseudohypoparathyroidism
0.000 0.650 0.349
E20.0 Idiopathic hypoparathyroidism
0.000 0.650 0.349
E75.2 Other sphingolipidosis
0.000 0.651 0.349
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.651 0.348
E26.9 Hyperaldosteronism, unspecified
0.000 0.656 0.344
E26.8 Other hyperaldosteronism
0.000 0.656 0.344
E26.1 Secondary hyperaldosteronism
0.000 0.656 0.344
E06 Thyroiditis
0.008 0.658 0.333
E29.8 Other testicular dysfunction
0.000 0.658 0.341
E29.0 Testicular hyperfunction
0.000 0.658 0.341
K90.3 Pancreatic steatorrhoea
0.000 0.662 0.338
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.662 0.338
K90.1 Tropical sprue
0.000 0.662 0.338
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.663 0.337
K90.8 Other intestinal malabsorption
0.000 0.665 0.335
E07.8 Other specified disorders of thyroid
0.004 0.666 0.330
E22.1 Hyperprolactinaemia
0.000 0.675 0.325
E29.1 Testicular hypofunction
0.000 0.677 0.323
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.678 0.322
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.679 0.321
E88.9 Metabolic disorder, unspecified
0.001 0.679 0.320
E13.8 With unspecified complications
0.001 0.690 0.309
E13.7 With multiple complications
0.001 0.690 0.309
E13.6 With other specified complications
0.001 0.690 0.309
E13.5 With peripheral circulatory complications
0.001 0.690 0.309
E13.4 With neurological complications
0.001 0.690 0.309
E13.2 With renal complications
0.001 0.690 0.309
E13.1 With ketoacidosis
0.001 0.690 0.309
E13.0 With coma
0.001 0.690 0.309
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.691 0.308
N41.9 Inflammatory disease of prostate, unspecified
0.305 0.695 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.697 0.303
E24 Cushing's syndrome
0.001 0.698 0.301
E80.6 Other disorders of bilirubin metabolism
0.000 0.699 0.301
E78.4 Other hyperlipidaemia
0.000 0.699 0.301
E29.9 Testicular dysfunction, unspecified
0.000 0.700 0.300
G36 Other acute disseminated demyelination
0.000 0.705 0.295
E20.9 Hypoparathyroidism, unspecified
0.000 0.706 0.294
N43.2 Other hydrocele
0.294 0.706 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.706 0.294
E80.5 Crigler-Najjar syndrome
0.000 0.706 0.294
E80.3 Defects of catalase and peroxydase
0.000 0.706 0.294
E80.0 Hereditary erythropoietic porphyria
0.000 0.706 0.294
C21.8 Overlapping lesion of rectum, anus and anal canal
0.293 0.707 0.000
E75.5 Other lipid storage disorders
0.001 0.707 0.292
G37 Other demyelinating diseases of central nervous system
0.000 0.708 0.292
E04 Other non-toxic goitre
0.002 0.709 0.289
N43.1 Infected hydrocele
0.283 0.717 0.000
N43.0 Encysted hydrocele
0.282 0.718 0.000
E26.0 Primary hyperaldosteronism
0.000 0.719 0.281
E05.5 Thyroid crisis or storm
0.003 0.721 0.276
E05.4 Thyrotoxicosis factitia
0.003 0.721 0.276
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.003 0.721 0.276
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.003 0.721 0.276
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.009 0.724 0.268
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.009 0.724 0.268
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.009 0.724 0.268
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.009 0.724 0.268
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.009 0.724 0.268
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.009 0.724 0.268
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.009 0.724 0.268
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.009 0.724 0.268
E78.6 Lipoprotein deficiency
0.000 0.726 0.274
E07.1 Dyshormogenetic goitre
0.008 0.729 0.263
E07.0 Hypersecretion of calcitonin
0.008 0.729 0.263
N42.0 Calculus of prostate
0.270 0.730 0.001
E67 Other hyperalimentation
0.000 0.730 0.270
E68 Sequelae of hyperalimentation
0.000 0.730 0.270
E13.3 With ophthalmic complications
0.001 0.731 0.268
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.732 0.268
E53.8 Deficiency of other specified B group vitamins
0.000 0.733 0.267
E06.9 Thyroiditis, unspecified
0.004 0.733 0.263
E23.2 Diabetes insipidus
0.000 0.734 0.265
E80.2 Other porphyria
0.000 0.736 0.263

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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