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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77443150
log Bayes Factor = 15.8315
Chromosome 22   position 49,290,992  (GRCh37) Explore rs77443150 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M54.56 Low back pain (Lumbar region)
0.999 0.001 0.000
N10-N16 Renal tubulo-interstitial diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
N13 Obstructive and reflux uropathy
0.998 0.002 0.000
N20-N23 Urolithiasis
0.991 0.009 0.000
N30-N39 Other diseases of urinary system
0.988 0.012 0.000
N40-N51 Diseases of male genital organs
0.982 0.018 0.000
N35 Urethral stricture
0.979 0.021 0.000
N13.3 Other and unspecified hydronephrosis
0.978 0.022 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
N35.9 Urethral stricture, unspecified
0.973 0.027 0.000
M54.59 Low back pain (Site unspecified)
0.967 0.033 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.964 0.036 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.964 0.036 0.000
M54.9 Dorsalgia, unspecified
0.963 0.037 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.963 0.037 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.963 0.037 0.000
S60-S69 Injuries to the wrist and hand
0.963 0.037 0.000
Chapter XX External causes of morbidity and mortality
0.960 0.040 0.000
S00-S09 Injuries to the head
0.960 0.040 0.000
Chapter VII Diseases of the eye and adnexa
0.943 0.057 0.000
Chapter II Neoplasms
0.941 0.059 0.000
N23 Unspecified renal colic
0.941 0.059 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.939 0.061 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.937 0.063 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.924 0.076 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.920 0.080 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
M65-M68 Disorders of synovium and tendon
0.919 0.081 0.000
E10-E14 Diabetes mellitus
0.916 0.084 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.908 0.092 0.000
M54.57 Low back pain (Lumbosacral region)
0.904 0.096 0.000
N32 Other disorders of bladder
0.900 0.100 0.000
E11 Non-insulin-dependent diabetes mellitus
0.900 0.100 0.000
H53-H54 Visual disturbances and blindness
0.899 0.101 0.000
S62 Fracture at wrist and hand level
0.895 0.105 0.000
N20 Calculus of kidney and ureter
0.895 0.105 0.000
M70-M79 Other soft tissue disorders
0.895 0.105 0.000
N10 Acute tubulo-interstitial nephritis
0.894 0.106 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.893 0.107 0.000
Chapter VIII Diseases of the ear and mastoid process
0.893 0.107 0.000
M54.2 Cervicalgia
0.892 0.108 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.889 0.111 0.000
N17-N19 Renal failure
0.887 0.113 0.000
N21 Calculus of lower urinary tract
0.884 0.116 0.000
S00 Superficial injury of head
0.878 0.122 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.871 0.129 0.000
S02 Fracture of skull and facial bones
0.871 0.129 0.000
S90-S99 Injuries to the ankle and foot
0.866 0.134 0.000
C50-C50 Malignant neoplasm of breast
0.866 0.134 0.000
M80-M85 Disorders of bone density and structure
0.864 0.136 0.000
V10-V19 Pedal cyclist injured in transport accident
0.861 0.139 0.000
N36 Other disorders of urethra
0.860 0.140 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.859 0.141 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.858 0.142 0.000
N20.0 Calculus of kidney
0.857 0.143 0.000
N42 Other disorders of prostate
0.856 0.144 0.000
N32.0 Bladder-neck obstruction
0.852 0.148 0.000
D50-D53 Nutritional anaemias
0.852 0.148 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.851 0.149 0.000
M51 Other intervertebral disk disorders
0.851 0.149 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.849 0.151 0.000
H53 Visual disturbances
0.848 0.152 0.000
N00-N08 Glomerular diseases
0.844 0.156 0.000
Q80-Q89 Other congenital malformations
0.839 0.161 0.000
M65 Synovitis and tenosynovitis
0.838 0.162 0.000
N17 Acute renal failure
0.836 0.164 0.000
N13.4 Hydroureter
0.829 0.171 0.000
M54.6 Pain in thoracic spine
0.826 0.174 0.000
N11 Chronic tubulo-interstitial nephritis
0.825 0.175 0.000
M24 Other specific joint derangements
0.824 0.176 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.822 0.178 0.000
M86-M90 Other osteopathies
0.821 0.179 0.000
C64-C68 Malignant neoplasms of urinary tract
0.819 0.181 0.000
H43-H45 Disorders of vitreous body and globe
0.819 0.181 0.000
M54.50 Low back pain (Multiple sites in spine)
0.819 0.181 0.000
E11.1 With ketoacidosis
0.814 0.186 0.000
C50 Malignant neoplasm of breast
0.812 0.188 0.000
C60-C63 Malignant neoplasms of male genital organs
0.810 0.190 0.000
D51 Vitamin B12 deficiency anaemia
0.809 0.191 0.000
N21.0 Calculus in bladder
0.808 0.192 0.000
M54.22 Cervicalgia (Cervical region)
0.804 0.196 0.000
H53.8 Other visual disturbances
0.804 0.196 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.803 0.197 0.000
L89 Decubitus ulcer
0.803 0.197 0.000
E11.3 With ophthalmic complications
0.803 0.197 0.000
C50.4 Upper-outer quadrant of breast
0.802 0.198 0.000
L60-L75 Disorders of skin appendages
0.801 0.199 0.000
S00.5 Superficial injury of lip and oral cavity
0.796 0.204 0.000
M54.1 Radiculopathy
0.796 0.204 0.000
M91-M94 Chondropathies
0.796 0.204 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.794 0.206 0.000
E11.5 With peripheral circulatory complications
0.794 0.206 0.000
H65-H75 Diseases of middle ear and mastoid
0.792 0.208 0.000
M65.3 Trigger finger
0.791 0.209 0.000
M35 Other systemic involvement of connective tissue
0.791 0.209 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.790 0.210 0.000
Chapter IX Diseases of the circulatory system
0.790 0.210 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.788 0.212 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.787 0.213 0.000
L84 Corns and callosities
0.787 0.213 0.000
N48 Other disorders of penis
0.787 0.213 0.000
N17.9 Acute renal failure, unspecified
0.787 0.213 0.000
N42.8 Other specified disorders of prostate
0.787 0.213 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.786 0.214 0.000
H30-H36 Disorders of choroid and retina
0.785 0.215 0.000
E20-E35 Disorders of other endocrine glands
0.785 0.215 0.000
N50 Other disorders of male genital organs
0.785 0.215 0.000
E50-E64 Other nutritional deficiencies
0.784 0.216 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.779 0.221 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.779 0.221 0.000
S06 Intracranial injury
0.775 0.224 0.000
H90-H95 Other disorders of ear
0.775 0.225 0.000
Chapter X Diseases of the respiratory system
0.775 0.225 0.000
S50-S59 Injuries to the elbow and forearm
0.774 0.226 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
D80-D89 Certain disorders involving the immune mechanism
0.770 0.230 0.000
S02.0 Fracture of vault of skull
0.769 0.231 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.768 0.232 0.000
N13.8 Other obstructive and reflux uropathy
0.763 0.237 0.000
E11.2 With renal complications
0.762 0.238 0.000
S62.6 Fracture of other finger
0.761 0.239 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.760 0.240 0.000
Q50-Q56 Congenital malformations of genital organs
0.758 0.242 0.000
M65.34 Trigger finger-Hand
0.758 0.242 0.000
L90 Atrophic disorders of skin
0.758 0.242 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.755 0.245 0.000
N25-N29 Other disorders of kidney and ureter
0.751 0.249 0.000
M77 Other enthesopathies
0.750 0.250 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.750 0.250 0.000
Q82 Other congenital malformations of skin
0.749 0.251 0.000
M25 Other joint disorders, not elsewhere classified
0.749 0.251 0.000
S60 Superficial injury of wrist and hand
0.748 0.252 0.000
N32.8 Other specified disorders of bladder
0.748 0.252 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.747 0.253 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.745 0.255 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.742 0.258 0.000
N99-N99 Other disorders of the genitourinary system
0.742 0.258 0.000
H54 Blindness and low vision
0.740 0.260 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.740 0.260 0.000
M80 Osteoporosis with pathological fracture
0.739 0.261 0.000
Q60-Q64 Congenital malformations of the urinary system
0.738 0.262 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.738 0.262 0.000
E14 Unspecified diabetes mellitus
0.738 0.262 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
S62.3 Fracture of other metacarpal bone
0.736 0.264 0.000
T66-T78 Other and unspecified effects of external causes
0.734 0.266 0.000
C61 Malignant neoplasm of prostate
0.734 0.266 0.000
L85 Other epidermal thickening
0.734 0.266 0.000
M22 Disorders of patella
0.733 0.267 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.732 0.268 0.000
M67 Other disorders of synovium and tendon
0.732 0.268 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.732 0.268 0.000
M31 Other necrotising vasculopathies
0.731 0.269 0.000
Chapter V Mental and behavioural disorders
0.730 0.270 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.729 0.271 0.000
S92 Fracture of foot, except ankle
0.729 0.271 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.728 0.272 0.000
N45 Orchitis and epididymitis
0.727 0.273 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.727 0.273 0.000
I05-I09 Chronic rheumatic heart diseases
0.727 0.273 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.725 0.275 0.000
M21 Other acquired deformities of limbs
0.725 0.275 0.000
S68 Traumatic amputation of wrist and hand
0.720 0.280 0.000
W00-W19 Falls
0.719 0.281 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.282 0.000
M54.8 Other dorsalgia
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.55 Low back pain (Thoracolumbar region)
0.717 0.283 0.000
M54.54 Low back pain-Thoracic
0.717 0.283 0.000
M54.53 Low back pain-Cervicothoracic
0.717 0.283 0.000
M54.52 Low back pain-Cervical
0.717 0.283 0.000
M54.51 Low back pain-Occipit-atl-axl
0.717 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.717 0.283 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.716 0.283 0.000
N15 Other renal tubulo-interstitial diseases
0.716 0.283 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.716 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.716 0.284 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.715 0.284 0.000
N13.6 Pyonephrosis
0.715 0.284 0.000
N36.1 Urethral diverticulum
0.715 0.285 0.000
M79.6 Pain in limb
0.714 0.286 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.714 0.286 0.000
M54.4 Lumbago with sciatica
0.714 0.286 0.000
H53.2 Diplopia
0.714 0.286 0.000
L93 Lupus erythematosus
0.714 0.286 0.000
C66 Malignant neoplasm of ureter
0.713 0.287 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.712 0.288 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.711 0.289 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.710 0.289 0.000
H10-H13 Disorders of conjunctiva
0.710 0.290 0.000
N02 Recurrent and persistent haematuria
0.709 0.291 0.000
N37 Urethral disorders in diseases classified elsewhere
0.708 0.292 0.000
N34 Urethritis and urethral syndrome
0.708 0.292 0.000
N33 Bladder disorders in diseases classified elsewhere
0.708 0.292 0.000
S67 Crushing injury of wrist and hand
0.707 0.293 0.000
N48.6 Balanitis xerotica obliterans
0.707 0.293 0.000
H55-H59 Other disorders of eye and adnexa
0.705 0.294 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.704 0.296 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.704 0.296 0.000
N46 Male infertility
0.704 0.296 0.000
N44 Torsion of testis
0.704 0.296 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.703 0.297 0.000
S62.60 Fracture of other finger (closed)
0.702 0.298 0.000
N35.8 Other urethral stricture
0.702 0.298 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.702 0.298 0.000
N35.0 Posttraumatic urethral stricture
0.702 0.298 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.701 0.298 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
M24.1 Other articular cartilage disorders
0.700 0.300 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.700 0.300 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.699 0.301 0.000
H34 Retinal vascular occlusions
0.699 0.301 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.699 0.301 0.000
M72 Fibroblastic disorders
0.698 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.698 0.302 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.698 0.302 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.697 0.303 0.000
S91 Open wound of ankle and foot
0.697 0.303 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.697 0.303 0.000
S02.00 Fracture of vault of skull (closed)
0.696 0.304 0.000
E11.6 With other specified complications
0.696 0.304 0.000
L82 Seborrhoeic keratosis
0.696 0.304 0.000
S00.1 Contusion of eyelid and periocular area
0.694 0.306 0.000
M51.9 Intervertebral disk disorder, unspecified
0.694 0.306 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.691 0.309 0.000
S09 Other and unspecified injuries of head
0.691 0.309 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.691 0.309 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.691 0.309 0.000
Q35-Q37 Cleft lip and cleft palate
0.691 0.309 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.309 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.691 0.309 0.000
Q00-Q07 Congenital malformations of the nervous system
0.691 0.309 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.691 0.309 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.691 0.309 0.000
L94 Other localised connective tissue disorders
0.691 0.309 0.000
L87 Transepidermal elimination disorders
0.691 0.309 0.000
L88 Pyoderma gangrenosum
0.691 0.309 0.000
L86 Keratoderma in diseases classified elsewhere
0.691 0.309 0.000
L83 Acanthosis nigricans
0.691 0.309 0.000
L80 Vitiligo
0.691 0.309 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.691 0.309 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.691 0.309 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.691 0.309 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.691 0.309 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.691 0.309 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.691 0.309 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.691 0.309 0.000
S00.3 Superficial injury of nose
0.691 0.309 0.000
T87 Complications peculiar to reattachment and amputation
0.691 0.309 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.691 0.309 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.691 0.309 0.000
S65 Injury of blood vessels at wrist and hand level
0.690 0.310 0.000
M40-M43 Deforming dorsopathies
0.690 0.310 0.000
Q39 Congenital malformations of oesophagus
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.689 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
Y00-Y09 Assault
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
E65-E68 Obesity and other hyperalimentation
0.689 0.311 0.000
S08 Traumatic amputation of part of head
0.688 0.312 0.000
S07 Crushing injury of head
0.688 0.312 0.000
S05 Injury of eye and orbit
0.688 0.312 0.000
S04 Injury of cranial nerves
0.688 0.312 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.688 0.312 0.000
S62.2 Fracture of first metacarpal bone
0.686 0.314 0.000
H44 Disorders of globe
0.685 0.315 0.000
Q82.8 Other specified congenital malformations of skin
0.685 0.315 0.000
L40-L45 Papulosquamous disorders
0.684 0.316 0.000
H74 Other disorders of middle ear and mastoid
0.684 0.316 0.000
S61 Open wound of wrist and hand
0.683 0.317 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.682 0.318 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.680 0.320 0.000
M45-M49 Spondylopathies
0.680 0.320 0.000
M84 Disorders of continuity of bone
0.678 0.322 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.676 0.324 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.675 0.325 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.675 0.325 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.675 0.325 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.675 0.325 0.000
J95-J99 Other diseases of the respiratory system
0.674 0.326 0.000
M85 Other disorders of bone density and structure
0.674 0.326 0.000
Q43 Other congenital malformations of intestine
0.674 0.326 0.000
N36.0 Urethral fistula
0.673 0.326 0.000
V18.0 Driver injured in nontraffic accident
0.673 0.327 0.000
L50-L54 Urticaria and erythema
0.673 0.327 0.000
H66 Suppurative and unspecified otitis media
0.673 0.327 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.672 0.328 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.672 0.328 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.672 0.328 0.000
S69 Other and unspecified injuries of wrist and hand
0.671 0.328 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.671 0.329 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
N05 Unspecified nephritic syndrome
0.671 0.329 0.000
C51-C58 Malignant neoplasms of female genital organs
0.671 0.329 0.000
D00-D09 In situ neoplasms
0.671 0.329 0.000
L72.1 Trichilemmal cyst
0.671 0.329 0.000
M54.29 Cervicalgia-Site unspe
0.670 0.329 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
E53 Deficiency of other B group vitamins
0.668 0.332 0.000
L90.5 Scar conditions and fibrosis of skin
0.668 0.332 0.000
C71 Malignant neoplasm of brain
0.667 0.333 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.667 0.333 0.000
S02.5 Fracture of tooth
0.666 0.334 0.000
J09-J18 Influenza and pneumonia
0.666 0.334 0.000
H43 Disorders of vitreous body
0.665 0.335 0.000
I74 Arterial embolism and thrombosis
0.664 0.336 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.664 0.336 0.000
L81 Other disorders of pigmentation
0.663 0.337 0.000
N17.0 Acute renal failure with tubular necrosis
0.662 0.338 0.000
S02.6 Fracture of mandible
0.662 0.338 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.662 0.338 0.000
N36.2 Urethral caruncle
0.662 0.338 0.000
D52 Folate deficiency anaemia
0.662 0.338 0.000
C67 Malignant neoplasm of bladder
0.661 0.339 0.000
N40 Hyperplasia of prostate
0.661 0.339 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.661 0.339 0.000
Chapter VI Diseases of the nervous system
0.660 0.340 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.660 0.340 0.000
E40-E46 Malnutrition
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.659 0.341 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.659 0.341 0.000
M66 Spontaneous rupture of synovium and tendon
0.659 0.341 0.000
L91 Hypertrophic disorders of skin
0.658 0.342 0.000
H53.0 Amblyopia ex anopsia
0.658 0.342 0.000
M24.5 Contracture of joint
0.657 0.342 0.000
E12 Malnutrition-related diabetes mellitus
0.656 0.343 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.656 0.344 0.000
S02.1 Fracture of base of skull
0.655 0.345 0.000
S02.3 Fracture of orbital floor
0.655 0.345 0.000
C50.5 Lower-outer quadrant of breast
0.655 0.345 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.654 0.346 0.000
H93 Other disorders of ear, not elsewhere classified
0.654 0.346 0.000
T82.3 Mechanical complication of other vascular grafts
0.653 0.347 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.652 0.348 0.000
D55-D59 Haemolytic anaemias
0.651 0.349 0.000
M89 Other disorders of bone
0.650 0.350 0.000
T82.1 Mechanical complication of cardiac electronic device
0.650 0.350 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.650 0.350 0.000
M35.0 Sicca syndrome [Sjogren]
0.650 0.350 0.000
M51.2 Other specified intervertebral disk displacement
0.650 0.350 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.648 0.351 0.000
E29 Testicular dysfunction
0.647 0.353 0.000
S32 Fracture of lumbar spine and pelvis
0.647 0.353 0.000
M35.3 Polymyalgia rheumatica
0.646 0.354 0.000
N32.4 Rupture of bladder, nontraumatic
0.645 0.355 0.000
N32.2 Vesical fistula, not elsewhere classified
0.645 0.355 0.000
N32.1 Vesicointestinal fistula
0.645 0.355 0.000
E11.8 With unspecified complications
0.645 0.355 0.000
E11.7 With multiple complications
0.645 0.355 0.000
E11.0 With coma
0.645 0.355 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.645 0.355 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.644 0.356 0.000
E13 Other specified diabetes mellitus
0.644 0.356 0.000
S00.9 Superficial injury of head, part unspecified
0.644 0.356 0.000
S20-S29 Injuries to the thorax
0.643 0.357 0.000
I77 Other disorders of arteries and arterioles
0.643 0.357 0.000
S62.7 Multiple fractures of fingers
0.642 0.358 0.000
S62.5 Fracture of thumb
0.642 0.358 0.000
S62.4 Multiple fractures of metacarpal bones
0.642 0.358 0.000
S62.1 Fracture of other carpal bone(s)
0.642 0.358 0.000
M25.4 Effusion of joint
0.642 0.358 0.000
N20.9 Urinary calculus, unspecified
0.642 0.358 0.000
M76 Enthesopathies of lower limb, excluding foot
0.642 0.358 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.642 0.358 0.000
M71 Other bursopathies
0.642 0.358 0.000
Y52 Agents primarily affecting the cardiovascular system
0.641 0.358 0.000
H53.4 Visual field defects
0.641 0.359 0.000
I08 Multiple valve diseases
0.641 0.359 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.640 0.360 0.000
M54.27 Cervicalgia-Lumbosacral
0.640 0.360 0.000
M54.26 Cervicalgia-Lumbar
0.640 0.360 0.000
M54.25 Cervicalgia-Thoracolumbar
0.640 0.360 0.000
M54.24 Cervicalgia-Thoracic
0.640 0.360 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.640 0.360 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.640 0.360 0.000
M54.20 Cervicalgia-Mult site
0.640 0.360 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.639 0.361 0.000
H36 Retinal disorders in diseases classified elsewhere
0.639 0.361 0.000
M54.16 Radiculopathy (Lumbar region)
0.637 0.363 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.636 0.364 0.000
H60-H62 Diseases of external ear
0.636 0.364 0.000
H34.8 Other retinal vascular occlusions
0.635 0.365 0.000
S02.4 Fracture of malar and maxillary bones
0.635 0.365 0.000
S63.6 Sprain and strain of finger(s)
0.634 0.366 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.634 0.366 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.634 0.366 0.000
N21.8 Other lower urinary tract calculus
0.634 0.366 0.000
N21.1 Calculus in urethra
0.634 0.366 0.000
M87 Osteonecrosis
0.634 0.366 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.632 0.368 0.000
D86 Sarcoidosis
0.631 0.369 0.000
M25.8 Other specified joint disorders
0.631 0.369 0.000
M24.2 Disorder of ligament
0.631 0.369 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.631 0.369 0.000
H92 Otalgia and effusion of ear
0.630 0.370 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.630 0.370 0.000
S00.7 Multiple superficial injuries of head
0.629 0.371 0.000
S00.4 Superficial injury of ear
0.629 0.371 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.629 0.371 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.629 0.371 0.000
N50.8 Other specified disorders of male genital organs
0.628 0.372 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.627 0.373 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.627 0.373 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.627 0.373 0.000
M54.3 Sciatica
0.626 0.373 0.000
M77.1 Lateral epicondylitis
0.626 0.373 0.000
Y57 Other and unspecified drugs and medicaments
0.626 0.374 0.000
M94 Other disorders of cartilage
0.625 0.375 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.625 0.375 0.000
S02.8 Fractures of other skull and facial bones
0.625 0.375 0.000
S02.7 Multiple fractures involving skull and facial bones
0.625 0.375 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.625 0.375 0.000
M86 Osteomyelitis
0.624 0.375 0.000
C32 Malignant neoplasm of larynx
0.624 0.376 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.623 0.377 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.622 0.378 0.000
N18 Chronic renal failure
0.621 0.379 0.000
S99 Other and unspecified injuries of ankle and foot
0.621 0.379 0.000
S98 Traumatic amputation of ankle and foot
0.621 0.379 0.000
S97 Crushing injury of ankle and foot
0.621 0.379 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.621 0.379 0.000
S95 Injury of blood vessels at ankle and foot level
0.621 0.379 0.000
S94 Injury of nerves at ankle and foot level
0.621 0.379 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.621 0.379 0.000
S90 Superficial injury of ankle and foot
0.621 0.379 0.000
S00.0 Superficial injury of scalp
0.621 0.379 0.000
L89.2 Stage III decubitus ulcer
0.620 0.380 0.000
M83 Adult osteomalacia
0.620 0.380 0.000
M82 Osteoporosis in diseases classified elsewhere
0.620 0.380 0.000
M51.8 Other specified intervertebral disk disorders
0.619 0.381 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.617 0.382 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.617 0.382 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.617 0.382 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.617 0.382 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.617 0.382 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.617 0.382 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.617 0.382 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.617 0.382 0.000
N36.9 Urethral disorder, unspecified
0.617 0.383 0.000
N36.3 Prolapsed urethral mucosa
0.617 0.383 0.000
L73 Other follicular disorders
0.617 0.383 0.000
I05 Rheumatic mitral valve diseases
0.616 0.384 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.616 0.384 0.000
S37 Injury of urinary and pelvic organs
0.616 0.384 0.000
S36 Injury of intra-abdominal organs
0.616 0.384 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.616 0.384 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.616 0.384 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.616 0.384 0.000
S31 Open wound of abdomen, lower back and pelvis
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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