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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7745413
log Bayes Factor = 16.7491
Chromosome 6   position 29,915,469  (GRCh37) Explore rs7745413 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.004 0.996
L40.9 Psoriasis, unspecified
0.000 0.005 0.995
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.010 0.990
L40 Psoriasis
0.000 0.012 0.988
L40.5 Arthropathic psoriasis
0.000 0.018 0.982
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.047 0.953
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.117 0.883
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.123 0.877
E06 Thyroiditis
0.000 0.126 0.874
E16 Other disorders of pancreatic internal secretion
0.000 0.127 0.873
E16.2 Hypoglycaemia, unspecified
0.000 0.127 0.873
E89.0 Postprocedural hypothyroidism
0.000 0.156 0.844
L40.8 Other psoriasis
0.000 0.158 0.842
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.166 0.834
E70-E90 Metabolic disorders
0.000 0.174 0.826
L40.0 Psoriasis vulgaris
0.000 0.229 0.771
E06.9 Thyroiditis, unspecified
0.000 0.264 0.736
E03.8 Other specified hypothyroidism
0.000 0.272 0.728
E06.3 Autoimmune thyroiditis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E03.1 Congenital hypothyroidism without goitre
0.000 0.285 0.715
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.286 0.714
E00 Congenital iodine-deficiency syndrome
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E07 Other disorders of thyroid
0.000 0.288 0.712
E83 Disorders of mineral metabolism
0.000 0.290 0.710
L40.4 Guttate psoriasis
0.000 0.291 0.709
L40.3 Pustulosis palmaris et plantaris
0.000 0.291 0.709
L40.2 Acrodermatitis continua
0.000 0.291 0.709
L40.1 Generalised pustular psoriasis
0.000 0.291 0.709
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.297 0.703
E83.1 Disorders of iron metabolism
0.000 0.303 0.697
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.327 0.673
E89.2 Postprocedural hypoparathyroidism
0.000 0.333 0.667
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.338 0.661
E15 Nondiabetic hypoglycaemic coma
0.000 0.371 0.629
E06.5 Other chronic thyroiditis
0.000 0.373 0.626
E06.4 Drug-induced thyroiditis
0.000 0.373 0.626
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.373 0.626
E06.1 Subacute thyroiditis
0.000 0.373 0.626
E06.0 Acute thyroiditis
0.000 0.373 0.626
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.374 0.626
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.374 0.626
E16.4 Abnormal secretion of gastrin
0.000 0.374 0.626
E16.3 Increased secretion of glucagon
0.000 0.374 0.626
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.384 0.616
E10-E14 Diabetes mellitus
0.000 0.402 0.598
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.402 0.598
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.402 0.598
E89.5 Postprocedural testicular hypofunction
0.000 0.402 0.598
E89.1 Postprocedural hypoinsulinaemia
0.000 0.402 0.598
E05.8 Other thyrotoxicosis
0.000 0.404 0.596
E84 Cystic fibrosis
0.000 0.408 0.592
E77 Disorders of glycoprotein metabolism
0.000 0.408 0.592
E76 Disorders of glycosaminoglycan metabolism
0.000 0.408 0.592
E72 Other disorders of amino-acid metabolism
0.000 0.408 0.592
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.408 0.592
E70 Disorders of aromatic amino-acid metabolism
0.000 0.408 0.592
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.408 0.592
E16.1 Other hypoglycaemia
0.000 0.410 0.590
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.411 0.589
E89.3 Postprocedural hypopituitarism
0.000 0.427 0.573
E74 Other disorders of carbohydrate metabolism
0.000 0.433 0.567
E89.4 Postprocedural ovarian failure
0.000 0.433 0.567
E80.4 Gilbert's syndrome
0.000 0.436 0.564
E40-E46 Malnutrition
0.000 0.440 0.560
E07.9 Disorder of thyroid, unspecified
0.000 0.443 0.557
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.446 0.554
E79 Disorders of purine and pyrimidine metabolism
0.000 0.457 0.543
E13 Other specified diabetes mellitus
0.000 0.474 0.526
E73 Lactose intolerance
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.512
E07.1 Dyshormogenetic goitre
0.000 0.490 0.510
E07.0 Hypersecretion of calcitonin
0.000 0.490 0.510
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.491 0.509
E83.8 Other disorders of mineral metabolism
0.000 0.491 0.509
E83.2 Disorders of zinc metabolism
0.000 0.491 0.509
E83.0 Disorders of copper metabolism
0.000 0.491 0.509
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.517 0.483
E80.6 Other disorders of bilirubin metabolism
0.000 0.517 0.483
E80.5 Crigler-Najjar syndrome
0.000 0.517 0.483
E80.3 Defects of catalase and peroxydase
0.000 0.517 0.483
E80.2 Other porphyria
0.000 0.517 0.483
E80.1 Porphyria cutanea tarda
0.000 0.517 0.483
E80.0 Hereditary erythropoietic porphyria
0.000 0.517 0.483
E11 Non-insulin-dependent diabetes mellitus
0.000 0.523 0.477
E83.3 Disorders of phosphorus metabolism
0.000 0.524 0.476
E85 Amyloidosis
0.000 0.525 0.475
E13.9 Without complications
0.000 0.525 0.475
K90 Intestinal malabsorption
0.000 0.529 0.471
L40-L45 Papulosquamous disorders
0.000 0.529 0.471
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.544 0.455
E07.8 Other specified disorders of thyroid
0.000 0.553 0.447
E65-E68 Obesity and other hyperalimentation
0.000 0.555 0.445
E11.3 With ophthalmic complications
0.000 0.560 0.440
E11.5 With peripheral circulatory complications
0.000 0.571 0.429
E12 Malnutrition-related diabetes mellitus
0.000 0.571 0.429
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.575 0.425
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.575 0.425
E70.3 Albinism
0.000 0.575 0.425
E70.2 Disorders of tyrosine metabolism
0.000 0.575 0.425
E70.1 Other hyperphenylalaninaemias
0.000 0.575 0.425
E70.0 Classical phenylketonuria
0.000 0.575 0.425
E71.3 Disorders of fatty-acid metabolism
0.000 0.575 0.425
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.575 0.425
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.575 0.425
E71.0 Maple-syrup-urine disease
0.000 0.575 0.425
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.575 0.425
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.575 0.425
E72.5 Disorders of glycine metabolism
0.000 0.575 0.425
E72.4 Disorders of ornithine metabolism
0.000 0.575 0.425
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.575 0.425
E72.2 Disorders of urea cycle metabolism
0.000 0.575 0.425
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.575 0.425
E72.0 Disorders of amino-acid transport
0.000 0.575 0.425
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.575 0.425
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.575 0.425
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.575 0.425
E76.2 Other mucopolysaccharidoses
0.000 0.575 0.425
E76.1 Mucopolysaccharidosis, type II
0.000 0.575 0.425
E76.0 Mucopolysaccharidosis, type I
0.000 0.575 0.425
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.575 0.425
E77.8 Other disorders of glycoprotein metabolism
0.000 0.575 0.425
E77.1 Defects in glycoprotein degradation
0.000 0.575 0.425
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.575 0.425
E84.9 Cystic fibrosis, unspecified
0.000 0.575 0.425
E84.8 Cystic fibrosis with other manifestations
0.000 0.575 0.425
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.575 0.425
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.575 0.425
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.593 0.407
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.593 0.407
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.593 0.407
E74.2 Disorders of galactose metabolism
0.000 0.593 0.407
E74.1 Disorders of fructose metabolism
0.000 0.593 0.407
E74.0 Glycogen storage disease
0.000 0.593 0.407
E11.1 With ketoacidosis
0.000 0.595 0.405
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.598 0.401
E45 Retarded development following protein-energy malnutrition
0.000 0.598 0.401
E43 Unspecified severe protein-energy malnutrition
0.000 0.598 0.401
E42 Marasmic kwashiorkor
0.000 0.598 0.401
E41 Nutritional marasmus
0.000 0.598 0.401
E40 Kwashiorkor
0.000 0.598 0.401
E75.6 Lipid storage disorder, unspecified
0.000 0.602 0.397
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.602 0.397
E75.3 Sphingolipidosis, unspecified
0.000 0.602 0.397
E75.2 Other sphingolipidosis
0.000 0.602 0.397
E75.1 Other gangliosidosis
0.000 0.602 0.397
E75.0 GM2 gangliosidosis
0.000 0.602 0.397
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.611 0.389
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.611 0.389
E79.1 Lesch-Nyhan syndrome
0.000 0.611 0.389
E83.4 Disorders of magnesium metabolism
0.000 0.611 0.389
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.617 0.383
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.618 0.381
E13.8 With unspecified complications
0.000 0.622 0.377
E13.7 With multiple complications
0.000 0.622 0.377
E13.6 With other specified complications
0.000 0.622 0.377
E13.5 With peripheral circulatory complications
0.000 0.622 0.377
E13.4 With neurological complications
0.000 0.622 0.377
E13.3 With ophthalmic complications
0.000 0.622 0.377
E13.2 With renal complications
0.000 0.622 0.377
E13.1 With ketoacidosis
0.000 0.622 0.377
E13.0 With coma
0.000 0.622 0.377
E04 Other non-toxic goitre
0.000 0.624 0.376
K90.9 Intestinal malabsorption, unspecified
0.000 0.626 0.374
E73.8 Other lactose intolerance
0.000 0.630 0.370
E73.1 Secondary lactase deficiency
0.000 0.630 0.370
E73.0 Congenital lactase deficiency
0.000 0.630 0.370
E11.4 With neurological complications
0.000 0.640 0.360
E75.5 Other lipid storage disorders
0.000 0.640 0.360
L43 Lichen planus
0.000 0.641 0.359
E88 Other metabolic disorders
0.000 0.650 0.349
E11.7 With multiple complications
0.000 0.658 0.342
L42 Pityriasis rosea
0.000 0.658 0.342
E85.8 Other amyloidosis
0.000 0.659 0.341
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.659 0.341
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.659 0.341
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.659 0.341
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.660 0.340
K90.3 Pancreatic steatorrhoea
0.000 0.662 0.338
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.662 0.338
K90.1 Tropical sprue
0.000 0.662 0.338
L44 Other papulosquamous disorders
0.000 0.662 0.338
L41 Parapsoriasis
0.000 0.662 0.338
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.662 0.338
E85.4 Organ-limited amyloidosis
0.000 0.668 0.332
E46 Unspecified protein-energy malnutrition
0.000 0.672 0.328
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.673 0.327
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.673 0.327
K90.8 Other intestinal malabsorption
0.000 0.674 0.326
E10 Insulin-dependent diabetes mellitus
0.000 0.675 0.325
E11.8 With unspecified complications
0.000 0.677 0.323
E67 Other hyperalimentation
0.000 0.681 0.319
E68 Sequelae of hyperalimentation
0.000 0.681 0.319
E85.3 Secondary systemic amyloidosis
0.000 0.684 0.316
E12.9 Without complications
0.000 0.692 0.308
E12.8 With unspecified complications
0.000 0.692 0.308
E12.7 With multiple complications
0.000 0.692 0.308
E12.6 With other specified complications
0.000 0.692 0.308
E12.5 With peripheral circulatory complications
0.000 0.692 0.308
E12.4 With neurological complications
0.000 0.692 0.308
E12.3 With ophthalmic complications
0.000 0.692 0.308
E12.2 With renal complications
0.000 0.692 0.308
E12.1 With ketoacidosis
0.000 0.692 0.308
E12.0 With coma
0.000 0.692 0.308
L43.9 Lichen planus, unspecified
0.000 0.697 0.303
E78.1 Pure hyperglyceridaemia
0.000 0.701 0.299
E73.9 Lactose intolerance, unspecified
0.000 0.706 0.294
E50-E64 Other nutritional deficiencies
0.000 0.710 0.290
E65 Localised adiposity
0.000 0.711 0.289
E44.1 Mild protein-energy malnutrition
0.000 0.712 0.288
E44.0 Moderate protein-energy malnutrition
0.000 0.712 0.288
E78.6 Lipoprotein deficiency
0.000 0.712 0.287
E11.2 With renal complications
0.000 0.716 0.284
E20-E35 Disorders of other endocrine glands
0.000 0.717 0.283
E85.9 Amyloidosis, unspecified
0.000 0.724 0.276
E78.3 Hyperchylomicronaemia
0.000 0.726 0.274
E11.6 With other specified complications
0.000 0.730 0.270
E78.4 Other hyperlipidaemia
0.000 0.730 0.270
E04.8 Other specified non-toxic goitre
0.000 0.730 0.269
E10.5 With peripheral circulatory complications
0.000 0.731 0.269
E78.8 Other disorders of lipoprotein metabolism
0.000 0.732 0.268
E04.0 Non-toxic diffuse goitre
0.000 0.735 0.265
E11.0 With coma
0.000 0.738 0.262
L43.3 Subacute (active) lichen planus
0.000 0.743 0.257
L43.2 Lichenoid drug reaction
0.000 0.743 0.257
L43.1 Bullous lichen planus
0.000 0.743 0.257
L43.0 Hypertrophic lichen planus
0.000 0.743 0.257
E34 Other endocrine disorders
0.000 0.744 0.256
E10.0 With coma
0.000 0.747 0.253
E88.9 Metabolic disorder, unspecified
0.000 0.749 0.251
E88.8 Other specified metabolic disorders
0.000 0.749 0.251
E88.3 Tumour lysis syndrome
0.000 0.749 0.251
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.757 0.243
L41.9 Parapsoriasis, unspecified
0.000 0.758 0.242
L41.8 Other parapsoriasis
0.000 0.758 0.242
L41.5 Retiform parapsoriasis
0.000 0.758 0.242
L41.4 Large plaque parapsoriasis
0.000 0.758 0.242
L41.3 Small plaque parapsoriasis
0.000 0.758 0.242
L41.2 Lymphomatoid papulosis
0.000 0.758 0.242
L41.1 Pityriasis lichenoides chronica
0.000 0.758 0.242
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.758 0.242
L44.9 Papulosquamous disorder, unspecified
0.000 0.758 0.242
L44.8 Other specified papulosquamous disorders
0.000 0.758 0.242
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.758 0.242
L44.3 Lichen ruber moniliformis
0.000 0.758 0.242
L44.2 Lichen striatus
0.000 0.758 0.242
L44.1 Lichen nitidus
0.000 0.758 0.242
L44.0 Pityriasis rubra pilaris
0.000 0.758 0.242
E04.9 Non-toxic goitre, unspecified
0.000 0.758 0.242
E34.9 Endocrine disorder, unspecified
0.000 0.761 0.239
E10.6 With other specified complications
0.000 0.761 0.239
E10.7 With multiple complications
0.000 0.766 0.233
E78.5 Hyperlipidaemia, unspecified
0.000 0.767 0.233
E10.1 With ketoacidosis
0.000 0.769 0.231
E67.8 Other specified hyperalimentation
0.000 0.771 0.229
E67.3 Hypervitaminosis D
0.000 0.771 0.229
E67.2 Megavitamin-B6 syndrome
0.000 0.771 0.229
E67.1 Hypercarotenaemia
0.000 0.771 0.229
E67.0 Hypervitaminosis A
0.000 0.771 0.229
E10.3 With ophthalmic complications
0.000 0.778 0.222
E10.2 With renal complications
0.000 0.778 0.222
E10.8 With unspecified complications
0.000 0.782 0.218
E20 Hypoparathyroidism
0.000 0.787 0.213
L43.8 Other lichen planus
0.000 0.787 0.212
E28 Ovarian dysfunction
0.000 0.788 0.212
E10.4 With neurological complications
0.000 0.789 0.210
E78.2 Mixed hyperlipidaemia
0.000 0.791 0.208
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.792 0.208
E63 Other nutritional deficiencies
0.000 0.792 0.208
E56 Other vitamin deficiencies
0.000 0.792 0.208
E50 Vitamin A deficiency
0.000 0.792 0.208
E60 Dietary zinc deficiency
0.000 0.792 0.208
E59 Dietary selenium deficiency
0.000 0.792 0.208
E54 Ascorbic acid deficiency
0.000 0.792 0.208
E52 Niacin deficiency [pellagra]
0.000 0.792 0.208
E24 Cushing's syndrome
0.000 0.792 0.208
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.797 0.203
E32 Diseases of thymus
0.000 0.797 0.203
E31 Polyglandular dysfunction
0.000 0.797 0.203
E30 Disorders of puberty, not elsewhere classified
0.000 0.797 0.203
E25 Adrenogenital disorders
0.000 0.797 0.203
E51 Thiamine deficiency
0.000 0.798 0.202
E26 Hyperaldosteronism
0.000 0.798 0.202
E04.2 Non-toxic multinodular goitre
0.000 0.802 0.198
E29 Testicular dysfunction
0.000 0.807 0.193
E66 Obesity
0.000 0.810 0.190
E58 Dietary calcium deficiency
0.000 0.812 0.188
E88.2 Lipomatosis, not elsewhere classified
0.001 0.813 0.186
E14 Unspecified diabetes mellitus
0.000 0.816 0.184
E34.5 Androgen resistance syndrome
0.000 0.816 0.184
E34.4 Constitutional tall stature
0.000 0.816 0.184
E34.3 Short stature, not elsewhere classified
0.000 0.816 0.184
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.816 0.184
E34.1 Other hypersecretion of intestinal hormones
0.000 0.816 0.184
E61 Deficiency of other nutrient elements
0.000 0.817 0.183
E34.8 Other specified endocrine disorders
0.000 0.819 0.181
E28.3 Primary ovarian failure
0.000 0.821 0.179
E34.0 Carcinoid syndrome
0.000 0.822 0.178
E04.1 Non-toxic single thyroid nodule
0.000 0.827 0.173
E55 Vitamin D deficiency
0.000 0.836 0.164
E20.9 Hypoparathyroidism, unspecified
0.000 0.837 0.163
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.842 0.158
E24.9 Cushing's syndrome, unspecified
0.000 0.844 0.156
E20.8 Other hypoparathyroidism
0.000 0.847 0.153
E20.1 Pseudohypoparathyroidism
0.000 0.847 0.153
E20.0 Idiopathic hypoparathyroidism
0.000 0.847 0.153
E28.9 Ovarian dysfunction, unspecified
0.000 0.848 0.152
E28.8 Other ovarian dysfunction
0.000 0.848 0.152
E28.1 Androgen excess
0.000 0.848 0.152
E28.0 Oestrogen excess
0.000 0.848 0.152
E24.2 Drug-induced Cushing's syndrome
0.000 0.849 0.150
E50.9 Vitamin A deficiency, unspecified
0.000 0.850 0.149
E50.8 Other manifestations of vitamin A deficiency
0.000 0.850 0.149
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.850 0.149
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.850 0.149
E50.5 Vitamin A deficiency with night blindness
0.000 0.850 0.149
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.850 0.149
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.850 0.149
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.850 0.149
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.850 0.149
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.850 0.149
E56.9 Vitamin deficiency, unspecified
0.000 0.850 0.149
E56.8 Deficiency of other vitamins
0.000 0.850 0.149
E56.1 Deficiency of vitamin K
0.000 0.850 0.149
E56.0 Deficiency of vitamin E
0.000 0.850 0.149
E63.9 Nutritional deficiency, unspecified
0.000 0.850 0.149
E63.8 Other specified nutritional deficiencies
0.000 0.850 0.149
E63.1 Imbalance of constituents of food intake
0.000 0.850 0.149
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.850 0.149
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.850 0.149
E64.8 Sequelae of other nutritional deficiencies
0.000 0.850 0.149
E64.3 Sequelae of rickets
0.000 0.850 0.149
E64.2 Sequelae of vitamin C deficiency
0.000 0.850 0.149
E64.1 Sequelae of vitamin A deficiency
0.000 0.850 0.149
E64.0 Sequelae of protein-energy malnutrition
0.000 0.850 0.149
E24.8 Other Cushing's syndrome
0.000 0.850 0.149
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.850 0.149
E24.3 Ectopic ACTH syndrome
0.000 0.850 0.149
E24.1 Nelson's syndrome
0.000 0.850 0.149
E22 Hyperfunction of pituitary gland
0.000 0.850 0.149
E66.8 Other obesity
0.000 0.852 0.148
E24.0 Pituitary-dependent Cushing's disease
0.000 0.853 0.147
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.854 0.146
E25.9 Adrenogenital disorder, unspecified
0.000 0.854 0.146
E25.8 Other adrenogenital disorders
0.000 0.854 0.146
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.854 0.146
E30.9 Disorder of puberty, unspecified
0.000 0.854 0.146
E30.8 Other disorders of puberty
0.000 0.854 0.146
E30.1 Precocious puberty
0.000 0.854 0.146
E30.0 Delayed puberty
0.000 0.854 0.146
E31.9 Polyglandular dysfunction, unspecified
0.000 0.854 0.146
E31.8 Other polyglandular dysfunction
0.000 0.854 0.146
E31.1 Polyglandular hyperfunction
0.000 0.854 0.146
E31.0 Autoimmune polyglandular failure
0.000 0.854 0.146
E32.9 Disease of thymus, unspecified
0.000 0.854 0.146
E32.8 Other diseases of thymus
0.000 0.854 0.146
E32.1 Abscess of thymus
0.000 0.854 0.146
E32.0 Persistent hyperplasia of thymus
0.000 0.854 0.146
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.854 0.146
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.854 0.146
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.854 0.146
E51.9 Thiamine deficiency, unspecified
0.000 0.855 0.145
E51.8 Other manifestations of thiamine deficiency
0.000 0.855 0.145
E51.1 Beriberi
0.000 0.855 0.145
E26.9 Hyperaldosteronism, unspecified
0.000 0.855 0.145
E26.8 Other hyperaldosteronism
0.000 0.855 0.145
E26.1 Secondary hyperaldosteronism
0.000 0.855 0.145
E26.0 Primary hyperaldosteronism
0.000 0.856 0.144
E14.3 With ophthalmic complications
0.000 0.860 0.140
E51.2 Wernicke's encephalopathy
0.000 0.861 0.139
E61.2 Magnesium deficiency
0.000 0.861 0.139
E23 Hypofunction and other disorders of pituitary gland
0.000 0.861 0.139
E29.9 Testicular dysfunction, unspecified
0.000 0.861 0.138
E29.8 Other testicular dysfunction
0.000 0.861 0.138
E29.0 Testicular hyperfunction
0.000 0.861 0.138
E66.1 Drug-induced obesity
0.000 0.863 0.136
E53 Deficiency of other B group vitamins
0.000 0.867 0.133
E14.8 With unspecified complications
0.000 0.868 0.132
E14.7 With multiple complications
0.000 0.868 0.132
E14.6 With other specified complications
0.000 0.868 0.132
E14.5 With peripheral circulatory complications
0.000 0.868 0.132
E14.4 With neurological complications
0.000 0.868 0.132
E14.0 With coma
0.000 0.868 0.132
E61.9 Deficiency of nutrient element, unspecified
0.000 0.869 0.131
E61.8 Deficiency of other specified nutrient elements
0.000 0.869 0.131
E61.7 Deficiency of multiple nutrient elements
0.000 0.869 0.131
E61.6 Vanadium deficiency
0.000 0.869 0.131
E61.5 Molybdenum deficiency
0.000 0.869 0.131
E61.4 Chromium deficiency
0.000 0.869 0.131
E61.3 Manganese deficiency
0.000 0.869 0.131
E61.0 Copper deficiency
0.000 0.869 0.131
E29.1 Testicular hypofunction
0.000 0.872 0.128
E28.2 Polycystic ovarian syndrome
0.000 0.881 0.119
E14.1 With ketoacidosis
0.000 0.881 0.118
E55.0 Rickets, active
0.000 0.882 0.118
E23.2 Diabetes insipidus
0.000 0.887 0.112
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.893 0.107
E22.8 Other hyperfunction of pituitary gland
0.000 0.893 0.107
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.893 0.106
E14.2 Withrenal complications
0.001 0.896 0.103
E66.0 Obesity due to excess calories
0.000 0.900 0.100
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.900 0.100
E23.1 Drug-induced hypopituitarism
0.000 0.900 0.100
E10.9 Without complications
0.000 0.900 0.100
E27 Other disorders of adrenal gland
0.000 0.902 0.098
E23.6 Other disorders of pituitary gland
0.000 0.902 0.098
E53.1 Pyridoxine deficiency
0.000 0.904 0.095
E53.0 Riboflavin deficiency
0.000 0.904 0.095
E22.1 Hyperprolactinaemia
0.000 0.907 0.093
E61.1 Iron deficiency
0.000 0.908 0.092
E83.5 Disorders of calcium metabolism
0.000 0.911 0.089
E53.9 Vitamin B deficiency, unspecified
0.000 0.913 0.087
E23.7 Disorder of pituitary gland, unspecified
0.000 0.916 0.084
E22.0 Acromegaly and pituitary gigantism
0.000 0.921 0.079
E55.9 Vitamin D deficiency, unspecified
0.000 0.927 0.073
E27.5 Adrenomedullary hyperfunction
0.000 0.929 0.070
E27.0 Other adrenocortical overactivity
0.000 0.929 0.070
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.001 0.934 0.065
E27.1 Primary adrenocortical insufficiency
0.000 0.935 0.065
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.936 0.063
E27.8 Other specified disorders of adrenal gland
0.000 0.937 0.063
E27.2 Addisonian crisis
0.000 0.937 0.062
E27.9 Disorder of adrenal gland, unspecified
0.000 0.940 0.059
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.941 0.059
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.948 0.052
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.949 0.050
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.953 0.047
E21.4 Other specified disorders of parathyroid gland
0.001 0.953 0.047
E21.2 Other hyperparathyroidism
0.001 0.953 0.047
E53.8 Deficiency of other specified B group vitamins
0.000 0.959 0.041
E87.2 Acidosis
0.000 0.959 0.041
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.960 0.040
E21.3 Hyperparathyroidism, unspecified
0.000 0.961 0.039
E87.3 Alkalosis
0.000 0.961 0.039
E87.4 Mixed disorder of acid-base balance
0.000 0.963 0.036
E23.0 Hypopituitarism
0.001 0.964 0.036
E87.0 Hyperosmolality and hypernatraemia
0.000 0.965 0.035
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.966 0.034
K90-K93 Other diseases of the digestive system
0.000 0.969 0.031
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.970 0.029
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.975 0.025
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.977 0.023
E66.9 Obesity, unspecified
0.000 0.978 0.022
E86 Volume depletion
0.000 0.978 0.021
I70 Atherosclerosis
0.000 0.979 0.021
I70.0 Atherosclerosis of aorta
0.000 0.982 0.018
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.982 0.018
R60.9 Oedema, unspecified
0.000 0.983 0.017
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.983 0.016
K93.1 Megacolon in Chagas' disease
0.000 0.983 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.983 0.016
I70.1 Atherosclerosis of renal artery
0.000 0.983 0.016
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.984 0.016
I70.9 Generalised and unspecified atherosclerosis
0.000 0.984 0.015
I70.8 Atherosclerosis of other arteries
0.000 0.984 0.015
L20-L30 Dermatitis and eczema
0.000 0.985 0.015
L28 Lichen simplex chronicus and prurigo
0.000 0.986 0.014
R60.0 Localised oedema
0.000 0.986 0.014
R60 Oedema, not elsewhere classified
0.000 0.986 0.013
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.987 0.013
E87.7 Fluid overload
0.000 0.987 0.013
L10-L14 Bullous disorders
0.000 0.987 0.013
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.987 0.013
L50-L54 Urticaria and erythema
0.000 0.987 0.013
L30 Other dermatitis
0.000 0.987 0.013
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.988 0.012
L28.0 Lichen simplex chronicus
0.000 0.988 0.012
H66.9 Otitis media, unspecified
0.012 0.988 0.000
L21 Seborrhoeic dermatitis
0.000 0.988 0.012
L52 Erythema nodosum
0.000 0.988 0.012
L28.1 Prurigo nodularis
0.000 0.988 0.011
L25 Unspecified contact dermatitis
0.000 0.988 0.011
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.989 0.011
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.989 0.011
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.989 0.011
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.989 0.011
R44.3 Hallucinations, unspecified
0.000 0.989 0.011
L20 Atopic dermatitis
0.000 0.989 0.011
L24 Irritant contact dermatitis
0.000 0.989 0.011
L26 Exfoliative dermatitis
0.000 0.989 0.011
L22 Diaper [napkin] dermatitis
0.000 0.989 0.011
R31 Unspecified haematuria
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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