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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77455275
log Bayes Factor = 13.8714
Chromosome 1   position 24,627,899  (GRCh37) Explore rs77455275 on Ensembl!
Variant rs77455275 is part of Cluster X0019

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.999 0.001 0.000
Z87 Personal history of other diseases and conditions
0.998 0.002 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.992 0.008 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.985 0.015 0.000
K55-K64 Other diseases of intestines
0.982 0.018 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.970 0.030 0.000
N30-N39 Other diseases of urinary system
0.965 0.035 0.000
N81 Female genital prolapse
0.965 0.035 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.963 0.037 0.000
K63 Other diseases of intestine
0.963 0.037 0.000
N30 Cystitis
0.959 0.041 0.000
Z90.7 Acquired absence of genital organ(s)
0.957 0.043 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.956 0.044 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.953 0.047 0.000
M15-M19 Arthrosis
0.952 0.048 0.000
Chapter X Diseases of the respiratory system
0.940 0.060 0.000
Chapter V Mental and behavioural disorders
0.940 0.060 0.000
K50-K52 Noninfective enteritis and colitis
0.939 0.061 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.937 0.063 0.000
N81.1 Cystocele
0.936 0.064 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.935 0.065 0.000
Z91.5 Personal history of self-harm
0.929 0.071 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.925 0.075 0.000
K63.8 Other specified diseases of intestine
0.924 0.076 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.920 0.080 0.000
M50-M54 Other dorsopathies
0.918 0.082 0.000
N81.2 Incomplete uterovaginal prolapse
0.917 0.083 0.000
O00-O08 Pregnancy with abortive outcome
0.908 0.092 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.907 0.093 0.000
W00-W19 Falls
0.901 0.099 0.000
Z87.0 Personal history of diseases of the respiratory system
0.898 0.102 0.000
N30.2 Other chronic cystitis
0.897 0.103 0.000
Z87.8 Personal history of other specified conditions
0.896 0.104 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.892 0.108 0.000
S80-S89 Injuries to the knee and lower leg
0.889 0.111 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.889 0.111 0.000
Z98 Other postsurgical states
0.888 0.112 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.888 0.112 0.000
N17-N19 Renal failure
0.886 0.114 0.000
N30.9 Cystitis, unspecified
0.885 0.115 0.000
K60 Fissure and fistula of anal and rectal regions
0.883 0.117 0.000
Z95.1 Presence of aortocoronary bypass graft
0.882 0.118 0.000
M54 Dorsalgia
0.881 0.119 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.878 0.122 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.876 0.124 0.000
N72 Inflammatory disease of cervix uteri
0.876 0.124 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.876 0.124 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.874 0.126 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.874 0.126 0.000
Chapter VII Diseases of the eye and adnexa
0.870 0.130 0.000
N94.1 Dyspareunia
0.867 0.133 0.000
J95-J99 Other diseases of the respiratory system
0.866 0.134 0.000
Chapter I Certain infectious and parasitic diseases
0.866 0.134 0.000
S20-S29 Injuries to the thorax
0.864 0.136 0.000
N93 Other abnormal uterine and vaginal bleeding
0.860 0.140 0.000
K52 Other non-infective gastro-enteritis and colitis
0.858 0.142 0.000
K63.3 Ulcer of intestine
0.858 0.142 0.000
N89 Other noninflammatory disorders of vagina
0.857 0.143 0.000
Chapter VIII Diseases of the ear and mastoid process
0.857 0.143 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.856 0.144 0.000
K57 Diverticular disease of intestine
0.855 0.145 0.000
N32 Other disorders of bladder
0.852 0.148 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.851 0.149 0.000
M19 Other arthrosis
0.850 0.150 0.000
D68 Other coagulation defects
0.846 0.154 0.000
Chapter IX Diseases of the circulatory system
0.838 0.162 0.000
N00-N08 Glomerular diseases
0.835 0.165 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.834 0.166 0.000
N30.8 Other cystitis
0.833 0.167 0.000
N80 Endometriosis
0.833 0.167 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.832 0.168 0.000
Z93 Artificial opening status
0.832 0.168 0.000
M54.9 Dorsalgia, unspecified
0.831 0.169 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.831 0.169 0.000
M80-M85 Disorders of bone density and structure
0.830 0.170 0.000
L40-L45 Papulosquamous disorders
0.828 0.172 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.827 0.173 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.826 0.174 0.000
Z90.0 Acquired absence of part of head and neck
0.824 0.176 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.822 0.178 0.000
O60-O75 Complications of labour and delivery
0.821 0.179 0.000
H43-H45 Disorders of vitreous body and globe
0.821 0.179 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
J60-J70 Lung diseases due to external agents
0.817 0.183 0.000
N10-N16 Renal tubulo-interstitial diseases
0.815 0.185 0.000
E20-E35 Disorders of other endocrine glands
0.814 0.186 0.000
Z91.6 Personal history of other physical trauma
0.814 0.186 0.000
J98 Other respiratory disorders
0.811 0.189 0.000
Z98.0 Intestinal bypass and anastomosis status
0.811 0.189 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.810 0.190 0.000
M45-M49 Spondylopathies
0.809 0.191 0.000
O03 Spontaneous abortion
0.807 0.193 0.000
I20-I25 Ischaemic heart diseases
0.806 0.194 0.000
K01 Embedded and impacted teeth
0.804 0.196 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.804 0.196 0.000
K60.2 Anal fissure, unspecified
0.801 0.199 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.800 0.200 0.000
M16 Coxarthrosis [arthrosis of hip]
0.799 0.201 0.000
I25 Chronic ischaemic heart disease
0.798 0.202 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.796 0.203 0.000
J90-J94 Other diseases of pleura
0.793 0.207 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.793 0.207 0.000
N94.6 Dysmenorrhoea, unspecified
0.790 0.210 0.000
S90-S99 Injuries to the ankle and foot
0.789 0.211 0.000
O04 Medical abortion
0.789 0.211 0.000
A30-A49 Other bacterial diseases
0.787 0.213 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.787 0.213 0.000
K65-K67 Diseases of peritoneum
0.787 0.213 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.786 0.214 0.000
K55 Vascular disorders of intestine
0.785 0.215 0.000
H43 Disorders of vitreous body
0.785 0.215 0.000
N70 Salpingitis and oophoritis
0.784 0.216 0.000
M19.0 Primary arthrosis of other joints
0.782 0.218 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.782 0.218 0.000
M20-M25 Other joint disorders
0.776 0.224 0.000
S81 Open wound of lower leg
0.775 0.225 0.000
M91-M94 Chondropathies
0.774 0.226 0.000
N30.0 Acute cystitis
0.773 0.227 0.000
V10-V19 Pedal cyclist injured in transport accident
0.772 0.227 0.000
F10.0 Acute intoxication
0.770 0.229 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.770 0.230 0.000
E10-E14 Diabetes mellitus
0.770 0.230 0.000
M54.2 Cervicalgia
0.770 0.230 0.000
S82 Fracture of lower leg, including ankle
0.769 0.231 0.000
S10-S19 Injuries to the neck
0.769 0.231 0.000
M17 Gonarthrosis [arthrosis of knee]
0.768 0.232 0.000
Y86 Sequelae of other accidents
0.767 0.233 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.766 0.234 0.000
N94.3 Premenstrual tension syndrome
0.765 0.235 0.000
M40-M43 Deforming dorsopathies
0.765 0.235 0.000
Y57 Other and unspecified drugs and medicaments
0.765 0.235 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.762 0.238 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.761 0.239 0.000
N76 Other inflammation of vagina and vulva
0.761 0.239 0.000
N25-N29 Other disorders of kidney and ureter
0.761 0.239 0.000
N81.5 Vaginal enterocele
0.758 0.242 0.000
W18 Other fall on same level
0.756 0.244 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.755 0.245 0.000
K51 Ulcerative colitis
0.755 0.245 0.000
M18 Arthrosis of first carpometacarpal joint
0.755 0.245 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
S60-S69 Injuries to the wrist and hand
0.751 0.249 0.000
J00-J06 Acute upper respiratory infections
0.750 0.250 0.000
Z33 Pregnant state, incidental
0.750 0.250 0.000
S00-S09 Injuries to the head
0.749 0.251 0.000
M00-M03 Infectious arthropathies
0.748 0.251 0.000
V80-V89 Other land transport accidents
0.748 0.251 0.000
K50 Crohn's disease [regional enteritis]
0.748 0.252 0.000
Z36 Antenatal screening
0.748 0.252 0.000
N81.9 Female genital prolapse, unspecified
0.748 0.252 0.000
K58 Irritable bowel syndrome
0.747 0.253 0.000
T42.4 Benzodiazepines
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.746 0.254 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.746 0.254 0.000
L40 Psoriasis
0.746 0.254 0.000
T79-T79 Certain early complications of trauma
0.745 0.255 0.000
K63.5 Polyp of colon
0.744 0.256 0.000
H43.8 Other disorders of vitreous body
0.742 0.258 0.000
Z95.2 Presence of prosthetic heart valve
0.742 0.258 0.000
K01.1 Impacted teeth
0.742 0.258 0.000
N93.0 Postcoital and contact bleeding
0.741 0.259 0.000
D68.9 Coagulation defect, unspecified
0.740 0.260 0.000
M25 Other joint disorders, not elsewhere classified
0.739 0.261 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.736 0.264 0.000
W20-W49 Exposure to inanimate mechanical forces
0.735 0.265 0.000
W19 Unspecified fall
0.735 0.265 0.000
K83 Other diseases of biliary tract
0.734 0.266 0.000
O36 Maternal care for other known or suspected foetal problems
0.734 0.266 0.000
N99-N99 Other disorders of the genitourinary system
0.734 0.266 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.733 0.267 0.000
J98.1 Pulmonary collapse
0.732 0.267 0.000
N80.0 Endometriosis of uterus
0.732 0.268 0.000
D69 Purpura and other haemorrhagic conditions
0.731 0.269 0.000
M86-M90 Other osteopathies
0.731 0.269 0.000
N32.3 Diverticulum of bladder
0.730 0.270 0.000
J69 Pneumonitis due to solids and liquids
0.729 0.270 0.000
M16.9 Coxarthrosis, unspecified
0.729 0.271 0.000
N17 Acute renal failure
0.729 0.271 0.000
D68.5 Primary Thrombophilia
0.727 0.272 0.000
N75 Diseases of Bartholin's gland
0.727 0.273 0.000
N32.9 Bladder disorder, unspecified
0.726 0.274 0.000
X60-X84 Intentional self-harm
0.726 0.274 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.726 0.274 0.000
F10.1 Harmful use
0.726 0.274 0.000
Y40 Systemic antibiotics
0.725 0.275 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.725 0.275 0.000
K35-K38 Diseases of appendix
0.724 0.276 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.723 0.277 0.000
H65-H75 Diseases of middle ear and mastoid
0.723 0.277 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.722 0.278 0.000
N19 Unspecified renal failure
0.720 0.280 0.000
M51 Other intervertebral disk disorders
0.720 0.280 0.000
N89.5 Stricture and atresia of vagina
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
E23 Hypofunction and other disorders of pituitary gland
0.717 0.283 0.000
Z90.8 Acquired absence of other organs
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.715 0.284 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.715 0.285 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.715 0.285 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.715 0.285 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.712 0.288 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
S70-S79 Injuries to the hip and thigh
0.711 0.289 0.000
I25.2 Old myocardial infarction
0.711 0.289 0.000
W13 Fall from, out of or through building or structure
0.709 0.291 0.000
O40 Polyhydramnios
0.709 0.291 0.000
N98 Complications associated with artificial fertilisation
0.708 0.292 0.000
N91 Absent, scanty and rare menstruation
0.708 0.292 0.000
N82 Fistulae involving female genital tract
0.708 0.292 0.000
N96 Habitual aborter
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.706 0.294 0.000
Z91.7 Personal history of female genital mutilation
0.706 0.294 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.706 0.294 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.706 0.294 0.000
Z91.2 Personal history of poor personal hygiene
0.706 0.294 0.000
L85 Other epidermal thickening
0.705 0.295 0.000
N81.8 Other female genital prolapse
0.704 0.296 0.000
D80-D89 Certain disorders involving the immune mechanism
0.704 0.296 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.704 0.296 0.000
E14 Unspecified diabetes mellitus
0.704 0.296 0.000
Z95.0 Presence of cardiac pacemaker
0.704 0.296 0.000
O04.9 Complete or unspecified, without complication
0.703 0.297 0.000
O42 Premature rupture of membranes
0.702 0.298 0.000
N30.3 Trigonitis
0.702 0.298 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.701 0.299 0.000
O47 False labour
0.700 0.300 0.000
N30.1 Interstitial cystitis (chronic)
0.700 0.300 0.000
D60-D64 Aplastic and other anaemias
0.699 0.301 0.000
K00 Disorders of tooth development and eruption
0.699 0.301 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.697 0.303 0.000
O85-O92 Complications predominantly related to the puerperium
0.695 0.305 0.000
N71 Inflammatory disease of uterus, except cervix
0.694 0.306 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.694 0.306 0.000
A41 Other septicaemia
0.694 0.306 0.000
I24 Other acute ischaemic heart diseases
0.694 0.306 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.693 0.307 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.693 0.307 0.000
N37 Urethral disorders in diseases classified elsewhere
0.692 0.308 0.000
N34 Urethritis and urethral syndrome
0.692 0.308 0.000
N33 Bladder disorders in diseases classified elsewhere
0.692 0.308 0.000
N81.0 Female urethrocele
0.692 0.308 0.000
Y88 Sequelae of surgical and medical care as external cause
0.692 0.308 0.000
M25.5 Pain in joint
0.691 0.309 0.000
K02 Dental caries
0.691 0.309 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.691 0.309 0.000
Z95.3 Presence of xenogenic heart valve
0.691 0.309 0.000
N18 Chronic renal failure
0.691 0.309 0.000
K14 Diseases of tongue
0.691 0.309 0.000
K63.4 Enteroptosis
0.690 0.309 0.000
K63.2 Fistula of intestine
0.690 0.309 0.000
K63.1 Perforation of intestine (nontraumatic)
0.690 0.309 0.000
K63.0 Abscess of intestine
0.690 0.309 0.000
M54.22 Cervicalgia (Cervical region)
0.690 0.310 0.000
Z93.2 Ileostomy status
0.689 0.311 0.000
M17.9 Gonarthrosis, unspecified
0.689 0.311 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.689 0.311 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.689 0.311 0.000
K60.3 Anal fistula
0.688 0.312 0.000
F20 Schizophrenia
0.688 0.312 0.000
N30.4 Irradiation cystitis
0.687 0.312 0.000
N32.1 Vesicointestinal fistula
0.686 0.314 0.000
L40.9 Psoriasis, unspecified
0.686 0.314 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.685 0.315 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.685 0.315 0.000
O03.9 Complete or unspecified, without complication
0.684 0.316 0.000
K66 Other disorders of peritoneum
0.684 0.316 0.000
M45 Ankylosing spondylitis
0.684 0.316 0.000
O70 Perineal laceration during delivery
0.683 0.317 0.000
M53 Other dorsopathies, not elsewhere classified
0.683 0.317 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.683 0.317 0.000
N94.5 Secondary dysmenorrhoea
0.683 0.317 0.000
N94.4 Primary dysmenorrhoea
0.683 0.317 0.000
N94.2 Vaginismus
0.683 0.317 0.000
N94.0 Mittelschmerz
0.683 0.317 0.000
M15 Polyarthrosis
0.683 0.317 0.000
H04 Disorders of lachrymal system
0.680 0.320 0.000
H80-H83 Diseases of inner ear
0.680 0.320 0.000
F10.2 Dependence syndrome
0.680 0.320 0.000
Z90.3 Acquired absence of part of stomach
0.680 0.320 0.000
N80.9 Endometriosis, unspecified
0.679 0.321 0.000
Y52 Agents primarily affecting the cardiovascular system
0.678 0.321 0.000
N83.2 Other and unspecified ovarian cysts
0.678 0.322 0.000
Z95.4 Presence of other heart-valve replacement
0.677 0.323 0.000
K86 Other diseases of pancreas
0.676 0.324 0.000
S22.4 Multiple fractures of ribs
0.676 0.324 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.676 0.324 0.000
E27 Other disorders of adrenal gland
0.676 0.324 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.675 0.324 0.000
Z97 Presence of other devices
0.675 0.325 0.000
W06 Fall involving bed
0.674 0.325 0.000
T66-T78 Other and unspecified effects of external causes
0.674 0.326 0.000
F99-F99 Unspecified mental disorder
0.674 0.326 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.674 0.326 0.000
F80-F89 Disorders of psychological development
0.674 0.326 0.000
F70-F79 Mental retardation
0.674 0.326 0.000
F60-F69 Disorders of adult personality and behaviour
0.674 0.326 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.674 0.326 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.674 0.326 0.000
A00-A09 Intestinal infectious diseases
0.674 0.326 0.000
N81.3 Complete uterovaginal prolapse
0.673 0.326 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.673 0.327 0.000
Q50-Q56 Congenital malformations of genital organs
0.673 0.327 0.000
Z29 Need for other prophylactic measures
0.672 0.328 0.000
K04 Diseases of pulp and periapical tissues
0.672 0.328 0.000
L10-L14 Bullous disorders
0.672 0.328 0.000
H53-H54 Visual disturbances and blindness
0.672 0.328 0.000
O03.4 Incomplete, without complication
0.672 0.328 0.000
K83.1 Obstruction of bile duct
0.671 0.329 0.000
N80.2 Endometriosis of Fallopian tube
0.671 0.329 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.329 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.329 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.329 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.329 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.670 0.329 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.329 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.329 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.329 0.000
T36 Poisoning by systemic antibiotics
0.670 0.329 0.000
Z35 Supervision of high-risk pregnancy
0.670 0.329 0.000
S81.8 Open wound of other parts of lower leg
0.670 0.330 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.670 0.330 0.000
D68.0 Von Willebrand's disease
0.668 0.332 0.000
M84 Disorders of continuity of bone
0.668 0.332 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.668 0.332 0.000
N73 Other female pelvic inflammatory diseases
0.667 0.333 0.000
O62 Abnormalities of forces of labour
0.667 0.333 0.000
Z34 Supervision of normal pregnancy
0.667 0.333 0.000
J69.0 Pneumonitis due to food and vomit
0.667 0.333 0.000
O02 Other abnormal products of conception
0.666 0.334 0.000
N04 Nephrotic syndrome
0.666 0.334 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.666 0.334 0.000
K09 Cysts of oral region, not elsewhere classified
0.665 0.335 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.664 0.336 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.663 0.337 0.000
D55-D59 Haemolytic anaemias
0.663 0.337 0.000
K55.0 Acute vascular disorders of intestine
0.663 0.337 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.663 0.337 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.663 0.337 0.000
D68.2 Hereditary deficiency of other clotting factors
0.662 0.338 0.000
E40-E46 Malnutrition
0.662 0.338 0.000
W19.9 Unspecified place
0.661 0.339 0.000
K40-K46 Hernia
0.661 0.339 0.000
N70.1 Chronic salpingitis and oophoritis
0.661 0.339 0.000
M54.1 Radiculopathy
0.660 0.340 0.000
K63.9 Disease of intestine, unspecified
0.659 0.341 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.659 0.341 0.000
N13 Obstructive and reflux uropathy
0.659 0.341 0.000
L50-L54 Urticaria and erythema
0.659 0.341 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.658 0.342 0.000
O80-O84 Delivery
0.658 0.342 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.658 0.342 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.658 0.342 0.000
W07 Fall involving chair
0.657 0.343 0.000
J09-J18 Influenza and pneumonia
0.657 0.343 0.000
T51 Toxic effect of alcohol
0.656 0.344 0.000
B95-B98 Bacterial, viral and other infectious agents
0.656 0.344 0.000
O41 Other disorders of amniotic fluid and membranes
0.656 0.344 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.656 0.344 0.000
H43.3 Other vitreous opacities
0.656 0.344 0.000
K12 Stomatitis and related lesions
0.655 0.345 0.000
N32.0 Bladder-neck obstruction
0.655 0.345 0.000
M25.54 Pain in joint (Hand)
0.655 0.345 0.000
A49 Bacterial infection of unspecified site
0.653 0.347 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.653 0.347 0.000
E14.9 Without complications
0.652 0.348 0.000
E50-E64 Other nutritional deficiencies
0.652 0.348 0.000
J91 Pleural effusion in conditions classified elsewhere
0.651 0.349 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.651 0.349 0.000
O07 Failed attempted abortion
0.651 0.349 0.000
O06 Unspecified abortion
0.651 0.349 0.000
O05 Other abortion
0.651 0.349 0.000
O01 Hydatidiform mole
0.651 0.349 0.000
O00 Ectopic pregnancy
0.651 0.349 0.000
Z22 Carrier of infectious disease
0.651 0.349 0.000
I22 Subsequent myocardial infarction
0.651 0.349 0.000
K13 Other diseases of lip and oral mucosa
0.651 0.349 0.000
M65-M68 Disorders of synovium and tendon
0.650 0.350 0.000
H10-H13 Disorders of conjunctiva
0.650 0.350 0.000
O36.8 Maternal care for other specified foetal problems
0.650 0.350 0.000
Z90.1 Acquired absence of breast(s)
0.648 0.352 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.648 0.352 0.000
K70-K77 Diseases of liver
0.648 0.352 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.647 0.353 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.647 0.353 0.000
S20 Superficial injury of thorax
0.646 0.354 0.000
W17 Other fall from one level to another
0.646 0.354 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.646 0.354 0.000
W15 Fall from cliff
0.646 0.354 0.000
W14 Fall from tree
0.646 0.354 0.000
W12 Fall on and from scaffolding
0.646 0.354 0.000
W11 Fall on and from ladder
0.646 0.354 0.000
W10 Fall on and from stairs and steps
0.646 0.354 0.000
W09 Fall involving playground equipment
0.646 0.354 0.000
W08 Fall involving other furniture
0.646 0.354 0.000
W05 Fall involving wheelchair
0.646 0.354 0.000
W04 Fall while being carried or supported by other persons
0.646 0.354 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.646 0.354 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.646 0.354 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.646 0.354 0.000
W00 Fall on same level involving ice and snow
0.646 0.354 0.000
Y85 Sequelae of transport accidents
0.646 0.354 0.000
K50.9 Crohn's disease, unspecified
0.645 0.355 0.000
Z93.0 Tracheostomy status
0.645 0.355 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.644 0.356 0.000
Z36.8 Other antenatal screening
0.644 0.356 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.643 0.357 0.000
S68 Traumatic amputation of wrist and hand
0.642 0.358 0.000
A41.9 Septicaemia, unspecified
0.641 0.359 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.641 0.359 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.641 0.359 0.000
K10 Other diseases of jaws
0.640 0.360 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.640 0.360 0.000
K03 Other diseases of hard tissues of teeth
0.640 0.360 0.000
J40-J47 Chronic lower respiratory diseases
0.639 0.361 0.000
Z98.1 Arthrodesis status
0.638 0.361 0.000
Y57.9 Drug or medicament, unspecified
0.638 0.362 0.000
H65 Nonsuppurative otitis media
0.638 0.362 0.000
N92 Excessive, frequent and irregular menstruation
0.638 0.362 0.000
J90 Pleural effusion, not elsewhere classified
0.638 0.362 0.000
S89 Other and unspecified injuries of lower leg
0.637 0.363 0.000
S88 Traumatic amputation of lower leg
0.637 0.363 0.000
S87 Crushing injury of lower leg
0.637 0.363 0.000
S86 Injury of muscle and tendon at lower leg level
0.637 0.363 0.000
S85 Injury of blood vessels at lower leg level
0.637 0.363 0.000
S84 Injury of nerves at lower leg level
0.637 0.363 0.000
O48 Prolonged pregnancy
0.637 0.363 0.000
Z99.1 Dependence on respirator
0.637 0.363 0.000
Y59 Other and unspecified vaccines and biological substances
0.637 0.363 0.000
Y58 Bacterial vaccines
0.637 0.363 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.637 0.363 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.637 0.363 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.637 0.363 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.637 0.363 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.637 0.363 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.637 0.363 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
Y48 Anaesthetics and therapeutic gases
0.637 0.363 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.637 0.363 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.637 0.363 0.000
Y44 Agents primarily affecting blood constituents
0.637 0.363 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.637 0.363 0.000
S82.4 Fracture of fibula alone
0.637 0.363 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.637 0.363 0.000
D67 Hereditary factor IX deficiency
0.637 0.363 0.000
D66 Hereditary factor VIII deficiency
0.637 0.363 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.637 0.363 0.000
H30-H36 Disorders of choroid and retina
0.636 0.364 0.000
D69.6 Thrombocytopenia, unspecified
0.635 0.365 0.000
M80 Osteoporosis with pathological fracture
0.634 0.366 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.634 0.366 0.000
K60.5 Anorectal fistula
0.633 0.367 0.000
K60.4 Rectal fistula
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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