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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7745656
log Bayes Factor = 113.272
Chromosome 6   position 32,680,970  (GRCh37) Explore rs7745656 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.002 0.998
Chapter X Diseases of the respiratory system
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.998 0.002 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.002 0.998
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.003 0.997
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.004 0.996
M05-M14 Inflammatory polyarthropathies
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
K90.0 Coeliac disease
0.000 0.006 0.994
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.017 0.983
J20-J22 Other acute lower respiratory infections
0.000 0.018 0.982
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.021 0.979
E10.5 With peripheral circulatory complications
0.000 0.022 0.978
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.023 0.977
E10.2 With renal complications
0.000 0.026 0.974
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.027 0.973
E05.9 Thyrotoxicosis, unspecified
0.000 0.029 0.971
J22 Unspecified acute lower respiratory infection
0.000 0.033 0.967
L40.0 Psoriasis vulgaris
0.966 0.034 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.036 0.964
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.040 0.960
E14 Unspecified diabetes mellitus
0.000 0.040 0.960
E16 Other disorders of pancreatic internal secretion
0.000 0.046 0.954
M06.3 Rheumatoid nodule
0.000 0.053 0.947
M06.0 Seronegative rheumatoid arthritis
0.000 0.053 0.947
J80 Adult respiratory distress syndrome
0.000 0.056 0.944
J81 Pulmonary oedema
0.000 0.057 0.943
E16.2 Hypoglycaemia, unspecified
0.000 0.058 0.942
E14.3 With ophthalmic complications
0.000 0.062 0.938
J84 Other interstitial pulmonary diseases
0.000 0.062 0.938
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.075 0.925
M35.1 Other overlap syndromes
0.000 0.079 0.921
E06 Thyroiditis
0.000 0.080 0.920
E04 Other non-toxic goitre
0.000 0.089 0.911
M06.34 Rheumatoid nodule (Hand)
0.000 0.092 0.908
E10.0 With coma
0.000 0.137 0.863
L40.4 Guttate psoriasis
0.860 0.140 0.000
E06.3 Autoimmune thyroiditis
0.000 0.147 0.853
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.147 0.853
E10.8 With unspecified complications
0.000 0.149 0.851
E50-E64 Other nutritional deficiencies
0.000 0.155 0.845
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.156 0.844
J95-J99 Other diseases of the respiratory system
0.000 0.165 0.835
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.168 0.832
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.174 0.826
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.175 0.825
E04.0 Non-toxic diffuse goitre
0.000 0.179 0.821
L40.1 Generalised pustular psoriasis
0.813 0.187 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.189 0.811
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.190 0.810
E04.2 Non-toxic multinodular goitre
0.000 0.204 0.796
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.204 0.796
M06.4 Inflammatory polyarthropathy
0.000 0.207 0.793
L40.8 Other psoriasis
0.790 0.210 0.000
M35.2 Behcet's disease
0.000 0.215 0.785
J42 Unspecified chronic bronchitis
0.000 0.220 0.780
J46 Status asthmaticus
0.000 0.222 0.778
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.223 0.777
J21 Acute bronchiolitis
0.000 0.223 0.777
E07 Other disorders of thyroid
0.000 0.226 0.774
L40.3 Pustulosis palmaris et plantaris
0.764 0.235 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.236 0.764
E10.6 With other specified complications
0.000 0.236 0.764
E20-E35 Disorders of other endocrine glands
0.000 0.245 0.755
J84.8 Other specified interstitial pulmonary diseases
0.000 0.248 0.752
J00-J06 Acute upper respiratory infections
0.000 0.251 0.749
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.252 0.747
J41 Simple and mucopurulent chronic bronchitis
0.000 0.255 0.745
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.261 0.739
E04.9 Non-toxic goitre, unspecified
0.000 0.271 0.729
E05.8 Other thyrotoxicosis
0.000 0.273 0.727
E27 Other disorders of adrenal gland
0.000 0.273 0.727
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.274 0.725
M12 Other specific arthropathies
0.000 0.275 0.725
E61 Deficiency of other nutrient elements
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.285 0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.285 0.715
M05.2 Rheumatoid vasculitis
0.000 0.285 0.715
M05.1 Rheumatoid lung disease
0.000 0.285 0.715
M05.0 Felty's syndrome
0.000 0.285 0.715
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.285 0.714
M08 Juvenile arthritis
0.000 0.285 0.714
E27.1 Primary adrenocortical insufficiency
0.000 0.286 0.714
E14.1 With ketoacidosis
0.000 0.295 0.705
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.296 0.703
E06.9 Thyroiditis, unspecified
0.000 0.297 0.703
E55 Vitamin D deficiency
0.000 0.298 0.702
E15 Nondiabetic hypoglycaemic coma
0.000 0.303 0.697
E14.5 With peripheral circulatory complications
0.000 0.303 0.697
M35.8 Other specified systemic involvement of connective tissue
0.000 0.304 0.696
J20 Acute bronchitis
0.000 0.312 0.688
E14.7 With multiple complications
0.000 0.312 0.688
E14.6 With other specified complications
0.000 0.312 0.688
E14.0 With coma
0.000 0.312 0.688
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.315 0.685
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.316 0.684
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.316 0.684
E16.4 Abnormal secretion of gastrin
0.000 0.316 0.684
E16.3 Increased secretion of glucagon
0.000 0.316 0.684
J33 Nasal polyp
0.000 0.318 0.682
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.319 0.681
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.320 0.679
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.321 0.679
M06.38 Rheumatoid nodule (Other)
0.000 0.321 0.679
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.321 0.679
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.321 0.679
M06.33 Rheumatoid nodule (Forearm)
0.000 0.321 0.679
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.321 0.679
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.321 0.679
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.321 0.679
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.321 0.679
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.321 0.679
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.321 0.679
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.321 0.679
J30-J39 Other diseases of upper respiratory tract
0.000 0.322 0.678
J84.0 Alveolar and parietoalveolar conditions
0.000 0.328 0.672
E14.8 With unspecified complications
0.000 0.332 0.668
E14.2 Withrenal complications
0.000 0.332 0.667
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.335 0.665
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.338 0.662
H36 Retinal disorders in diseases classified elsewhere
0.000 0.339 0.661
J33.9 Nasal polyp, unspecified
0.000 0.339 0.661
E06.5 Other chronic thyroiditis
0.000 0.340 0.660
E06.4 Drug-induced thyroiditis
0.000 0.340 0.660
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.340 0.660
E06.1 Subacute thyroiditis
0.000 0.340 0.660
E06.0 Acute thyroiditis
0.000 0.340 0.660
E14.9 Without complications
0.000 0.340 0.660
E04.8 Other specified non-toxic goitre
0.000 0.346 0.653
E40-E46 Malnutrition
0.000 0.356 0.644
E14.4 With neurological complications
0.000 0.358 0.642
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.361 0.639
J00 Acute nasopharyngitis [common cold]
0.000 0.361 0.639
J33.0 Polyp of nasal cavity
0.000 0.362 0.638
E27.8 Other specified disorders of adrenal gland
0.000 0.366 0.634
M35.7 Hypermobility syndrome
0.000 0.366 0.633
M14 Arthropathies in other diseases classified elsewhere
0.000 0.369 0.630
J21.9 Acute bronchiolitis, unspecified
0.000 0.370 0.630
J33.8 Other polyp of sinus
0.000 0.371 0.629
E28 Ovarian dysfunction
0.000 0.373 0.627
E07.8 Other specified disorders of thyroid
0.000 0.381 0.619
J99.0 Rheumatoid lung disease
0.000 0.385 0.615
M10 Gout
0.000 0.389 0.611
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.389 0.611
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.394 0.606
E63 Other nutritional deficiencies
0.000 0.394 0.606
E51 Thiamine deficiency
0.000 0.394 0.606
E50 Vitamin A deficiency
0.000 0.394 0.606
E60 Dietary zinc deficiency
0.000 0.394 0.606
E59 Dietary selenium deficiency
0.000 0.394 0.606
E54 Ascorbic acid deficiency
0.000 0.394 0.606
E52 Niacin deficiency [pellagra]
0.000 0.394 0.606
J98 Other respiratory disorders
0.000 0.397 0.603
E55.9 Vitamin D deficiency, unspecified
0.000 0.400 0.600
J96 Respiratory failure, not elsewhere classified
0.000 0.401 0.599
E61.1 Iron deficiency
0.000 0.403 0.597
J01 Acute sinusitis
0.000 0.405 0.595
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.406 0.594
E53 Deficiency of other B group vitamins
0.000 0.409 0.591
E56 Other vitamin deficiencies
0.000 0.412 0.588
J60-J70 Lung diseases due to external agents
0.000 0.414 0.586
E29 Testicular dysfunction
0.000 0.414 0.586
J43 Emphysema
0.000 0.423 0.577
E23 Hypofunction and other disorders of pituitary gland
0.000 0.424 0.576
E61.2 Magnesium deficiency
0.000 0.425 0.575
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.431 0.569
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.431 0.569
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.431 0.569
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.431 0.569
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.431 0.569
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.431 0.569
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.431 0.569
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.431 0.569
E26 Hyperaldosteronism
0.000 0.432 0.568
J09-J18 Influenza and pneumonia
0.000 0.437 0.563
J98.9 Respiratory disorder, unspecified
0.000 0.437 0.563
N48 Other disorders of penis
0.563 0.437 0.000
J41.0 Simple chronic bronchitis
0.000 0.437 0.562
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.442 0.558
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.443 0.557
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.443 0.557
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.443 0.557
E07.1 Dyshormogenetic goitre
0.000 0.445 0.555
E07.0 Hypersecretion of calcitonin
0.000 0.445 0.555
M12.3 Palindromic rheumatism
0.000 0.445 0.555
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.449 0.551
N48.1 Balanoposthitis
0.551 0.449 0.000
M20-M25 Other joint disorders
0.000 0.450 0.550
E34 Other endocrine disorders
0.000 0.451 0.549
N48.8 Other specified disorders of penis
0.548 0.452 0.000
J32 Chronic sinusitis
0.000 0.452 0.548
E07.9 Disorder of thyroid, unspecified
0.000 0.453 0.547
M11 Other crystal arthropathies
0.000 0.455 0.545
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.455 0.544
M34 Systemic sclerosis
0.000 0.456 0.544
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.459 0.541
E32 Diseases of thymus
0.000 0.459 0.541
E31 Polyglandular dysfunction
0.000 0.459 0.541
E30 Disorders of puberty, not elsewhere classified
0.000 0.459 0.541
E11 Non-insulin-dependent diabetes mellitus
0.000 0.465 0.535
J04 Acute laryngitis and tracheitis
0.000 0.465 0.535
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.466 0.534
J41.1 Mucopurulent chronic bronchitis
0.000 0.466 0.534
E16.1 Other hypoglycaemia
0.000 0.469 0.531
E58 Dietary calcium deficiency
0.000 0.471 0.529
N48.6 Balanitis xerotica obliterans
0.527 0.473 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.473 0.527
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.474 0.526
J40 Bronchitis, not specified as acute or chronic
0.000 0.475 0.525
E27.5 Adrenomedullary hyperfunction
0.000 0.479 0.521
E27.0 Other adrenocortical overactivity
0.000 0.479 0.521
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.480 0.519
M12.5 Traumatic arthropathy
0.000 0.480 0.519
M12.4 Intermittent hydrarthrosis
0.000 0.480 0.519
M12.1 Kaschin-Beck disease
0.000 0.480 0.519
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.480 0.519
J10 Influenza due to identified influenza virus
0.000 0.481 0.519
M34.9 Systemic sclerosis, unspecified
0.000 0.482 0.518
E61.9 Deficiency of nutrient element, unspecified
0.000 0.483 0.517
E61.8 Deficiency of other specified nutrient elements
0.000 0.483 0.517
E61.7 Deficiency of multiple nutrient elements
0.000 0.483 0.517
E61.6 Vanadium deficiency
0.000 0.483 0.517
E61.5 Molybdenum deficiency
0.000 0.483 0.517
E61.4 Chromium deficiency
0.000 0.483 0.517
E61.3 Manganese deficiency
0.000 0.483 0.517
E61.0 Copper deficiency
0.000 0.483 0.517
E11.3 With ophthalmic complications
0.000 0.484 0.516
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.487 0.513
M05.08 Felty's syndrome (Other)
0.000 0.487 0.513
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.487 0.513
M05.06 Felty's syndrome (Lower leg)
0.000 0.487 0.513
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.487 0.513
M05.04 Felty's syndrome (Hand)
0.000 0.487 0.513
M05.03 Felty's syndrome (Forearm)
0.000 0.487 0.513
M05.02 Felty's syndrome (Upper arm)
0.000 0.487 0.513
M05.01 Felty's syndrome (Shoulder region)
0.000 0.487 0.513
M05.00 Felty's syndrome (Multiple sites)
0.000 0.487 0.513
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.487 0.513
M05.18 Rheumatoid lung disease (Other)
0.000 0.487 0.513
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.487 0.513
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.487 0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.487 0.513
M05.14 Rheumatoid lung disease (Hand)
0.000 0.487 0.513
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.487 0.513
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.487 0.513
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.487 0.513
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.487 0.513
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.487 0.513
M05.28 Rheumatoid vasculitis (Other)
0.000 0.487 0.513
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.487 0.513
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.487 0.513
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.487 0.513
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.487 0.513
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.487 0.513
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.487 0.513
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.487 0.513
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.487 0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.487 0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.487 0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.487 0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.487 0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.487 0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.487 0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.487 0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.487 0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.487 0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.487 0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.487 0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.487 0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
J32.9 Chronic sinusitis, unspecified
0.000 0.487 0.513
M08.9 Juvenile arthritis, unspecified
0.000 0.488 0.512
M08.8 Other juvenile arthritis
0.000 0.488 0.512
M08.4 Pauciarticular juvenile arthritis
0.000 0.488 0.512
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.488 0.512
M08.2 Juvenile arthritis with systemic onset
0.000 0.488 0.512
M08.1 Juvenile ankylosing spondylitis
0.000 0.488 0.512
M08.0 Juvenile rheumatoid arthritis
0.000 0.488 0.512
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.488 0.512
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.488 0.512
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.488 0.512
M09.0 Juvenile arthritis in psoriasis
0.000 0.488 0.512
M10.0 Idiopathic gout
0.000 0.489 0.511
J20.9 Acute bronchitis, unspecified
0.000 0.492 0.508
J33.1 Polypoid sinus degeneration
0.000 0.493 0.507
E55.0 Rickets, active
0.000 0.496 0.503
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.498 0.502
J98.4 Other disorders of lung
0.000 0.500 0.500
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.500 0.500
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.502 0.498
E20 Hypoparathyroidism
0.000 0.503 0.496
J20.7 Acute bronchitis due to echovirus
0.000 0.506 0.493
J20.6 Acute bronchitis due to rhinovirus
0.000 0.506 0.493
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.506 0.493
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.506 0.493
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.506 0.493
J20.2 Acute bronchitis due to streptococcus
0.000 0.506 0.493
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.506 0.493
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.506 0.493
J98.1 Pulmonary collapse
0.000 0.510 0.490
M12.2 Villonodular synovitis (pigmented)
0.000 0.511 0.489
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.515 0.485
N48.0 Leukoplakia of penis
0.485 0.515 0.000
J06.9 Acute upper respiratory infection, unspecified
0.000 0.518 0.482
J37 Chronic laryngitis and laryngotracheitis
0.000 0.519 0.481
N48.4 Impotence of organic origin
0.475 0.525 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.526 0.474
J01.9 Acute sinusitis, unspecified
0.000 0.526 0.474
M34.8 Other forms of systemic sclerosis
0.000 0.527 0.473
L40-L45 Papulosquamous disorders
0.440 0.527 0.033
M34.1 CR(E)ST syndrome
0.000 0.528 0.472
J64 Unspecified pneumoconiosis
0.000 0.529 0.471
N48.2 Other inflammatory disorders of penis
0.470 0.530 0.000
E28.3 Primary ovarian failure
0.000 0.535 0.465
E29.1 Testicular hypofunction
0.000 0.536 0.464
N48.9 Disorder of penis, unspecified
0.463 0.537 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.538 0.462
E45 Retarded development following protein-energy malnutrition
0.000 0.538 0.462
E43 Unspecified severe protein-energy malnutrition
0.000 0.538 0.462
E42 Marasmic kwashiorkor
0.000 0.538 0.462
E41 Nutritional marasmus
0.000 0.538 0.462
E40 Kwashiorkor
0.000 0.538 0.462
J20.8 Acute bronchitis due to other specified organisms
0.000 0.539 0.461
E53.9 Vitamin B deficiency, unspecified
0.000 0.539 0.461
J02 Acute pharyngitis
0.000 0.540 0.460
E23.2 Diabetes insipidus
0.000 0.541 0.459
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.541 0.459
# Top node
0.000 0.542 0.458
J43.2 Centrilobular emphysema
0.000 0.544 0.456
E13 Other specified diabetes mellitus
0.001 0.545 0.454
E65-E68 Obesity and other hyperalimentation
0.000 0.545 0.455
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.548 0.452
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.548 0.452
M14.4 Arthropathy in amyloidosis
0.000 0.548 0.452
M14.3 Lipoid dermatoarthritis
0.000 0.548 0.452
M14.2 Diabetic arthropathy
0.000 0.548 0.452
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.548 0.452
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.548 0.452
G37 Other demyelinating diseases of central nervous system
0.000 0.549 0.451
E28.9 Ovarian dysfunction, unspecified
0.000 0.550 0.449
E28.8 Other ovarian dysfunction
0.000 0.550 0.449
E28.1 Androgen excess
0.000 0.550 0.449
E28.0 Oestrogen excess
0.000 0.550 0.449
M07 Psoriatic and enteropathic arthropathies
0.006 0.552 0.442
E11.1 With ketoacidosis
0.000 0.552 0.448
E22 Hyperfunction of pituitary gland
0.000 0.555 0.445
N48.5 Ulcer of penis
0.444 0.556 0.000
J01.0 Acute maxillary sinusitis
0.000 0.557 0.443
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.558 0.442
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.560 0.440
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.561 0.439
M10.4 Other secondary gout
0.000 0.562 0.438
M10.3 Gout due to impairment of renal function
0.000 0.562 0.438
M10.2 Drug-induced gout
0.000 0.562 0.438
M10.1 Lead-induced gout
0.000 0.562 0.438
G36 Other acute disseminated demyelination
0.000 0.562 0.438
J11 Influenza, virus not identified
0.000 0.563 0.437
E25 Adrenogenital disorders
0.000 0.564 0.436
M13 Other arthritis
0.000 0.565 0.435
E50.9 Vitamin A deficiency, unspecified
0.000 0.566 0.434
E50.8 Other manifestations of vitamin A deficiency
0.000 0.566 0.434
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.566 0.434
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.566 0.434
E50.5 Vitamin A deficiency with night blindness
0.000 0.566 0.434
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.566 0.434
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.566 0.434
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.566 0.434
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.566 0.434
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.566 0.434
E51.9 Thiamine deficiency, unspecified
0.000 0.566 0.434
E51.8 Other manifestations of thiamine deficiency
0.000 0.566 0.434
E51.2 Wernicke's encephalopathy
0.000 0.566 0.434
E51.1 Beriberi
0.000 0.566 0.434
E63.9 Nutritional deficiency, unspecified
0.000 0.566 0.434
E63.8 Other specified nutritional deficiencies
0.000 0.566 0.434
E63.1 Imbalance of constituents of food intake
0.000 0.566 0.434
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.566 0.434
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.566 0.434
E64.8 Sequelae of other nutritional deficiencies
0.000 0.566 0.434
E64.3 Sequelae of rickets
0.000 0.566 0.434
E64.2 Sequelae of vitamin C deficiency
0.000 0.566 0.434
E64.1 Sequelae of vitamin A deficiency
0.000 0.566 0.434
E64.0 Sequelae of protein-energy malnutrition
0.000 0.566 0.434
E26.0 Primary hyperaldosteronism
0.000 0.566 0.433
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.567 0.433
J98.3 Compensatory emphysema
0.000 0.568 0.432
J96.9 Respiratory failure, unspecified
0.000 0.570 0.429
J96.1 Chronic respiratory failure
0.000 0.570 0.429
J96.0 Acute respiratory failure
0.000 0.570 0.429
E34.0 Carcinoid syndrome
0.000 0.571 0.429
J01.8 Other acute sinusitis
0.000 0.573 0.427
J01.4 Acute pansinusitis
0.000 0.573 0.427
J01.3 Acute sphenoidal sinusitis
0.000 0.573 0.427
J01.2 Acute ethmoidal sinusitis
0.000 0.573 0.427
J01.1 Acute frontal sinusitis
0.000 0.573 0.427
J14 Pneumonia due to Haemophilus influenzae
0.000 0.574 0.426

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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