TreeWAS – Variant ID: rs7746082

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.9 Crohn's disease, unspecified	0.326	0.674	0.000
K50 Crohn's disease [regional enteritis]	0.315	0.685	0.000
K50.0 Crohn's disease of small intestine	0.304	0.696	0.000
K50.1 Crohn's disease of large intestine	0.281	0.719	0.000
K50.8 Other Crohn's disease	0.232	0.768	0.000
K50-K52 Noninfective enteritis and colitis	0.128	0.872	0.000
K51 Ulcerative colitis	0.109	0.891	0.000
K51.2 Ulcerative (chronic) proctitis	0.102	0.898	0.000
K51.5 Mucosal proctocolitis	0.100	0.900	0.000
E22 Hyperfunction of pituitary gland	0.082	0.918	0.000
E20-E35 Disorders of other endocrine glands	0.081	0.919	0.000
K51.8 Other ulcerative colitis	0.081	0.919	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.080	0.920	0.000
E22.0 Acromegaly and pituitary gigantism	0.080	0.920	0.000
E26 Hyperaldosteronism	0.077	0.923	0.000
E34 Other endocrine disorders	0.075	0.925	0.000
E26.0 Primary hyperaldosteronism	0.075	0.925	0.000
E22.1 Hyperprolactinaemia	0.071	0.929	0.000
E27 Other disorders of adrenal gland	0.071	0.929	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.069	0.931	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.069	0.931	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.068	0.932	0.000
E23 Hypofunction and other disorders of pituitary gland	0.067	0.933	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.067	0.933	0.000
E34.8 Other specified endocrine disorders	0.066	0.934	0.000
E20 Hypoparathyroidism	0.063	0.937	0.000
E34.9 Endocrine disorder, unspecified	0.062	0.938	0.000
E34.0 Carcinoid syndrome	0.061	0.939	0.000
E23.6 Other disorders of pituitary gland	0.059	0.941	0.000
E27.9 Disorder of adrenal gland, unspecified	0.059	0.941	0.000
E22.8 Other hyperfunction of pituitary gland	0.059	0.941	0.000
K51.9 Ulcerative colitis, unspecified	0.058	0.942	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.058	0.942	0.000
E32 Diseases of thymus	0.058	0.942	0.000
E31 Polyglandular dysfunction	0.058	0.942	0.000
E30 Disorders of puberty, not elsewhere classified	0.058	0.942	0.000
E24 Cushing's syndrome	0.057	0.943	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.057	0.943	0.000
K52 Other non-infective gastro-enteritis and colitis	0.057	0.943	0.000
E25 Adrenogenital disorders	0.056	0.944	0.000
E26.9 Hyperaldosteronism, unspecified	0.055	0.945	0.000
E26.8 Other hyperaldosteronism	0.055	0.945	0.000
E26.1 Secondary hyperaldosteronism	0.055	0.945	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.055	0.945	0.000
E29 Testicular dysfunction	0.055	0.945	0.000
E34.5 Androgen resistance syndrome	0.054	0.946	0.000
E34.4 Constitutional tall stature	0.054	0.946	0.000
E34.3 Short stature, not elsewhere classified	0.054	0.946	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.054	0.946	0.000
E34.1 Other hypersecretion of intestinal hormones	0.054	0.946	0.000
E23.7 Disorder of pituitary gland, unspecified	0.053	0.947	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.053	0.947	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.052	0.948	0.000
E27.5 Adrenomedullary hyperfunction	0.051	0.949	0.000
E27.0 Other adrenocortical overactivity	0.051	0.949	0.000
E20.9 Hypoparathyroidism, unspecified	0.050	0.950	0.000
E23.2 Diabetes insipidus	0.050	0.950	0.000
E24.2 Drug-induced Cushing's syndrome	0.049	0.951	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.048	0.951	0.000
E23.1 Drug-induced hypopituitarism	0.048	0.951	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.048	0.952	0.000
E27.8 Other specified disorders of adrenal gland	0.048	0.952	0.000
E20.8 Other hypoparathyroidism	0.045	0.955	0.000
E20.1 Pseudohypoparathyroidism	0.045	0.955	0.000
E20.0 Idiopathic hypoparathyroidism	0.045	0.955	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.045	0.955	0.000
K52.3 Indeterminate colitis	0.042	0.958	0.000
E27.2 Addisonian crisis	0.042	0.958	0.000
E30.9 Disorder of puberty, unspecified	0.042	0.958	0.000
E30.8 Other disorders of puberty	0.042	0.958	0.000
E30.1 Precocious puberty	0.042	0.958	0.000
E30.0 Delayed puberty	0.042	0.958	0.000
E31.9 Polyglandular dysfunction, unspecified	0.042	0.958	0.000
E31.8 Other polyglandular dysfunction	0.042	0.958	0.000
E31.1 Polyglandular hyperfunction	0.042	0.958	0.000
E31.0 Autoimmune polyglandular failure	0.042	0.958	0.000
E32.9 Disease of thymus, unspecified	0.042	0.958	0.000
E32.8 Other diseases of thymus	0.042	0.958	0.000
E32.1 Abscess of thymus	0.042	0.958	0.000
E32.0 Persistent hyperplasia of thymus	0.042	0.958	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.042	0.958	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.042	0.958	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.042	0.958	0.000
E24.8 Other Cushing's syndrome	0.041	0.959	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.041	0.959	0.000
E24.3 Ectopic ACTH syndrome	0.041	0.959	0.000
E24.1 Nelson's syndrome	0.041	0.959	0.000
E21.4 Other specified disorders of parathyroid gland	0.041	0.959	0.000
E21.2 Other hyperparathyroidism	0.041	0.959	0.000
E28 Ovarian dysfunction	0.041	0.959	0.000
E25.9 Adrenogenital disorder, unspecified	0.040	0.959	0.000
E25.8 Other adrenogenital disorders	0.040	0.959	0.000
E24.0 Pituitary-dependent Cushing's disease	0.040	0.960	0.000
E29.9 Testicular dysfunction, unspecified	0.040	0.960	0.000
E29.8 Other testicular dysfunction	0.040	0.960	0.000
E29.0 Testicular hyperfunction	0.040	0.960	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.038	0.961	0.000
E27.1 Primary adrenocortical insufficiency	0.038	0.962	0.000
E29.1 Testicular hypofunction	0.037	0.963	0.000
E23.0 Hypopituitarism	0.037	0.963	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.036	0.964	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.036	0.964	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.035	0.964	0.000
E28.9 Ovarian dysfunction, unspecified	0.029	0.970	0.000
E28.8 Other ovarian dysfunction	0.029	0.970	0.000
E28.1 Androgen excess	0.029	0.970	0.000
E28.0 Oestrogen excess	0.029	0.970	0.000
E24.9 Cushing's syndrome, unspecified	0.029	0.971	0.000
E21.0 Primary hyperparathyroidism	0.027	0.973	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.973	0.027
K51.4 Pseudopolyposis of colon	0.025	0.975	0.001
E28.2 Polycystic ovarian syndrome	0.024	0.976	0.000
E28.3 Primary ovarian failure	0.022	0.978	0.000
E21.3 Hyperparathyroidism, unspecified	0.018	0.982	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.016	0.984	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.987	0.013
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.987	0.013
Z95.2 Presence of prosthetic heart valve	0.000	0.987	0.013
K52.1 Toxic gastro-enteritis and colitis	0.009	0.989	0.002
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.989	0.011
Z95.3 Presence of xenogenic heart valve	0.000	0.991	0.009
H92.1 Otorrhoea	0.009	0.991	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.991	0.009
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.992	0.008
T43.6 Psychostimulants with abuse potential	0.007	0.993	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.993	0.000
M34.9 Systemic sclerosis, unspecified	0.007	0.993	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.007	0.993	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.993	0.007
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.994	0.006
T43.2 Other and unspecified antidepressants	0.006	0.994	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.994	0.006
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
T43.9 Psychotropic drug, unspecified	0.006	0.994	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
M34.8 Other forms of systemic sclerosis	0.006	0.994	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.994	0.006
M34 Systemic sclerosis	0.005	0.995	0.000
F20.9 Schizophrenia, unspecified	0.005	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
N42.8 Other specified disorders of prostate	0.000	0.995	0.005
T42.4 Benzodiazepines	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.995	0.005
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.995	0.005
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.995	0.005
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.995	0.005
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.995	0.005
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
T44.0 Anticholinesterase agents	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.005	0.995	0.000
O12.0 Gestational oedema	0.004	0.996	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.996	0.004
T40.4 Other synthetic narcotics	0.004	0.996	0.000
M34.1 CR(E)ST syndrome	0.004	0.996	0.000
L03.3 Cellulitis of trunk	0.004	0.996	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.004	0.996	0.000
M34.0 Progressive systemic sclerosis	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
R82.9 Other and unspecified abnormal finding in urine	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
T40.5 Cocaine	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
M79.7 Fibromyalgia	0.000	0.996	0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
J94.8 Other specified pleural conditions	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.996	0.000
T42.3 Barbiturates	0.003	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.996	0.000
T36.8 Other systemic antibiotics	0.003	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.996	0.000
T36.6 Rifamycins	0.003	0.996	0.000
T36.5 Aminoglycosides	0.003	0.996	0.000
T36.4 Tetracyclines	0.003	0.996	0.000
T36.2 Chloramphenicol group	0.003	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.996	0.000
F20 Schizophrenia	0.004	0.996	0.000
T36.3 Macrolides	0.003	0.996	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.997	0.003
H26.9 Cataract, unspecified	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.003	0.997	0.000
H92 Otalgia and effusion of ear	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
M79.78 Fibromyalgia (Other)	0.000	0.997	0.003
M79.77 Fibromyalgia (Ankle and foot)	0.000	0.997	0.003
M79.76 Fibromyalgia (Lower leg)	0.000	0.997	0.003
M79.75 Fibromyalgia (Pelvic region and thigh)	0.000	0.997	0.003
M79.74 Fibromyalgia (Hand)	0.000	0.997	0.003
M79.73 Fibromyalgia (Forearm)	0.000	0.997	0.003
M79.72 Fibromyalgia (Upper arm)	0.000	0.997	0.003
M79.71 Fibromyalgia (Shoulder region)	0.000	0.997	0.003
M79.70 Fibromyalgia (Multiple sites)	0.000	0.997	0.003
T42.1 Iminostilbenes	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
H04.2 Epiphora	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
Z74.0 Reduced mobility	0.000	0.997	0.003
F20.8 Other schizophrenia	0.003	0.997	0.000
F20.6 Simple schizophrenia	0.003	0.997	0.000
F20.4 Postschizophrenic depression	0.003	0.997	0.000
F20.3 Undifferentiated schizophrenia	0.003	0.997	0.000
F20.2 Catatonic schizophrenia	0.003	0.997	0.000
F20.1 Hebephrenic schizophrenia	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
O02.1 Missed abortion	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.003	0.997	0.000
F20.5 Residual schizophrenia	0.002	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
H04.4 Chronic inflammation of lachrymal passages	0.000	0.997	0.002
A41.8 Other specified septicaemia	0.000	0.997	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.002
H04 Disorders of lachrymal system	0.000	0.998	0.002
A41 Other septicaemia	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.000	0.998	0.002
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.002
Z74.1 Need for assistance with personal care	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
A41.9 Septicaemia, unspecified	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
L57.0 Actinic keratosis	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
H04.8 Other disorders of lachrymal system	0.000	0.998	0.002
L03.9 Cellulitis, unspecified	0.000	0.998	0.002
R06.2 Wheezing	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H04.6 Other changes in lachrymal passages	0.000	0.998	0.002
H04.0 Dacryoadenitis	0.000	0.998	0.002
A41.4 Septicaemia due to anaerobes	0.000	0.998	0.002
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
N42.2 Atrophy of prostate	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
Z74.8 Other problems related to care-provider dependency	0.000	0.998	0.002
Z74.3 Need for continuous supervision	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.001	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
N83.1 Corpus luteum cyst	0.000	0.998	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.000	0.998	0.002
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
H04.9 Disorder of lachrymal system, unspecified	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.001
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.998	0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.998	0.000
T45.5 Anticoagulants	0.001	0.998	0.001
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.998	0.000
O14.2 HELLP syndrome	0.001	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
H92.0 Otalgia	0.001	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.000	0.998	0.002
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.001	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.998	0.000
N76.0 Acute vaginitis	0.000	0.998	0.001
S10.9 Superficial injury of neck, part unspecified	0.001	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.999	0.000
N42 Other disorders of prostate	0.000	0.999	0.001
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.001	0.999	0.000
H25.9 Senile cataract, unspecified	0.000	0.999	0.001
S52.10 Fracture of upper end of radius (closed)	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
Z11.5 Special screening examination for other viral diseases	0.001	0.999	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.001	0.999	0.000
K76.9 Liver disease, unspecified	0.001	0.999	0.000
T51.0 Ethanol	0.001	0.999	0.000
R82 Other abnormal findings in urine	0.001	0.999	0.000
H02.5 Other disorders affecting eyelid function	0.000	0.999	0.001
J86.9 Pyothorax without fistula	0.000	0.999	0.001
L60.9 Nail disorder, unspecified	0.000	0.999	0.001
N89.5 Stricture and atresia of vagina	0.001	0.999	0.000
O86.4 Pyrexia of unknown origin following delivery	0.001	0.999	0.000
D73.0 Hyposplenism	0.001	0.999	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.000	0.999	0.001
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
F21 Schizotypal disorder	0.001	0.999	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.999	0.001
I97.1 Other functional disturbances following cardiac surgery	0.000	0.999	0.001
M79.2 Neuralgia and neuritis, unspecified	0.001	0.999	0.000
N90.6 Hypertrophy of vulva	0.000	0.999	0.001
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.001	0.999	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
F25 Schizoaffective disorders	0.001	0.999	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
N42.3 Dysplasia of prostate	0.000	0.999	0.001
X60.2 School, other institution and public administrative area	0.001	0.999	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.999	0.001
L11.0 Acquired keratosis follicularis	0.001	0.999	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.999	0.001
H27.0 Aphakia	0.000	0.999	0.001
K04.5 Chronic apical periodontitis	0.000	0.999	0.001
J20.9 Acute bronchitis, unspecified	0.000	0.999	0.001
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.001	0.999	0.000
R82.3 Haemoglobinuria	0.001	0.999	0.000
R82.2 Biliuria	0.001	0.999	0.000
R82.0 Chyluria	0.001	0.999	0.000
X60.8 Other specified place	0.001	0.999	0.000
X65.8 Other specified place	0.001	0.999	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.001	0.999	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.001	0.999	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.999	0.001
F22 Persistent delusional disorders	0.001	0.999	0.000
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
G95.2 Cord compression, unspecified	0.000	0.999	0.001
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.001	0.999	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
Z31.2 In vitro fertilisation	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.001	0.999	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.001	0.999	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.001	0.999	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.001	0.999	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.001	0.999	0.000
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
X62.0 Home	0.001	0.999	0.000
X62.8 Other specified place	0.001	0.999	0.000
X62.7 Farm	0.001	0.999	0.000
X62.6 Industrial and construction area	0.001	0.999	0.000
X62.5 Trade and service area	0.001	0.999	0.000
X62.4 Street and highway	0.001	0.999	0.000
X62.3 Sports and athletics area	0.001	0.999	0.000
X62.2 School, other institution and public administrative area	0.001	0.999	0.000
X62.1 Residential institution	0.001	0.999	0.000
M90 Osteopathies in diseases classified elsewhere	0.001	0.999	0.000
S82.50 Fracture of medial malleolus (closed)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations