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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77475581
log Bayes Factor = 28.0873
Chromosome 7   position 3,375,369  (GRCh37) Explore rs77475581 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
M45-M49 Spondylopathies
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.995 0.005 0.000
E78.0 Pure hypercholesterolaemia
0.994 0.006 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.994 0.006 0.000
M47 Spondylosis
0.994 0.006 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
R07 Pain in throat and chest
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
R07.3 Other chest pain
0.988 0.012 0.000
M23 Internal derangement of knee
0.988 0.012 0.000
R50-R69 General symptoms and signs
0.986 0.014 0.000
I44 Atrioventricular and left bundle-branch block
0.985 0.015 0.000
M47.8 Other spondylosis
0.984 0.016 0.000
K70-K77 Diseases of liver
0.983 0.017 0.000
I20 Angina pectoris
0.982 0.018 0.000
H30-H36 Disorders of choroid and retina
0.979 0.021 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
B95-B98 Bacterial, viral and other infectious agents
0.975 0.025 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.975 0.025 0.000
I20.0 Unstable angina
0.974 0.026 0.000
I45 Other conduction disorders
0.974 0.026 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.970 0.030 0.000
M47.86 Other spondylosis (Lumbar region)
0.969 0.031 0.000
M23.3 Other meniscus derangements
0.961 0.039 0.000
E10-E14 Diabetes mellitus
0.960 0.040 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.960 0.040 0.000
R69 Unknown and unspecified causes of morbidity
0.959 0.041 0.000
I50 Heart failure
0.955 0.045 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.949 0.051 0.000
Chapter XXI Factors influencing health status and contact with health services
0.947 0.053 0.000
B25-B34 Other viral diseases
0.947 0.053 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.946 0.054 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.945 0.055 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.945 0.055 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.944 0.056 0.000
K65-K67 Diseases of peritoneum
0.942 0.057 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.940 0.060 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.939 0.061 0.000
I45.1 Other and unspecified right bundle-branch block
0.937 0.063 0.000
I25.2 Old myocardial infarction
0.936 0.064 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.936 0.064 0.000
A30-A49 Other bacterial diseases
0.934 0.066 0.000
E83 Disorders of mineral metabolism
0.932 0.068 0.000
K02 Dental caries
0.928 0.072 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.927 0.073 0.000
K76 Other diseases of liver
0.926 0.074 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.924 0.076 0.000
Chapter VIII Diseases of the ear and mastoid process
0.923 0.077 0.000
H35 Other retinal disorders
0.921 0.079 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.920 0.080 0.000
R51 Headache
0.920 0.080 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.920 0.080 0.000
Chapter XIV Diseases of the genitourinary system
0.920 0.080 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.916 0.084 0.000
I44.0 Atrioventricular block, first degree
0.913 0.087 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.912 0.088 0.000
H53-H54 Visual disturbances and blindness
0.911 0.089 0.000
B34 Viral infection of unspecified site
0.909 0.091 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.907 0.093 0.000
E83.5 Disorders of calcium metabolism
0.907 0.093 0.000
M47.2 Other spondylosis with radiculopathy
0.902 0.098 0.000
K08 Other disorders of teeth and supporting structures
0.897 0.103 0.000
E11 Non-insulin-dependent diabetes mellitus
0.896 0.104 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.895 0.105 0.000
K70 Alcoholic liver disease
0.892 0.108 0.000
F41 Other anxiety disorders
0.891 0.109 0.000
F10.1 Harmful use
0.891 0.109 0.000
R73 Elevated blood glucose level
0.890 0.110 0.000
I50.0 Congestive heart failure
0.889 0.111 0.000
A41 Other septicaemia
0.886 0.114 0.000
I46 Cardiac arrest
0.884 0.116 0.000
I60-I69 Cerebrovascular diseases
0.884 0.116 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.882 0.118 0.000
R07.1 Chest pain on breathing
0.882 0.118 0.000
B34.9 Viral infection, unspecified
0.882 0.118 0.000
M23.8 Other internal derangements of knee
0.882 0.118 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.880 0.120 0.000
M35 Other systemic involvement of connective tissue
0.880 0.120 0.000
H52 Disorders of refraction and accommodation
0.879 0.121 0.000
K02.9 Dental caries, unspecified
0.878 0.122 0.000
R52 Pain, not elsewhere classified
0.877 0.123 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.875 0.125 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.872 0.128 0.000
I05-I09 Chronic rheumatic heart diseases
0.871 0.129 0.000
I44.1 Atrioventricular block, second degree
0.868 0.132 0.000
K66 Other disorders of peritoneum
0.866 0.134 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.864 0.136 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.862 0.138 0.000
E16 Other disorders of pancreatic internal secretion
0.862 0.138 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.861 0.139 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.860 0.140 0.000
R41.0 Disorientation, unspecified
0.860 0.140 0.000
M48 Other spondylopathies
0.857 0.143 0.000
N30-N39 Other diseases of urinary system
0.857 0.143 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.851 0.149 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.850 0.150 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.849 0.151 0.000
K74 Fibrosis and cirrhosis of liver
0.849 0.151 0.000
M80-M85 Disorders of bone density and structure
0.849 0.151 0.000
I24 Other acute ischaemic heart diseases
0.849 0.151 0.000
R73.9 Hyperglycaemia, unspecified
0.848 0.152 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.848 0.152 0.000
E00-E07 Disorders of thyroid gland
0.848 0.152 0.000
N10-N16 Renal tubulo-interstitial diseases
0.848 0.152 0.000
A41.9 Septicaemia, unspecified
0.847 0.153 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.845 0.155 0.000
H65-H75 Diseases of middle ear and mastoid
0.844 0.156 0.000
Chapter II Neoplasms
0.844 0.156 0.000
D50-D53 Nutritional anaemias
0.842 0.158 0.000
H53 Visual disturbances
0.841 0.159 0.000
I50.9 Heart failure, unspecified
0.841 0.159 0.000
H55-H59 Other disorders of eye and adnexa
0.840 0.160 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.839 0.161 0.000
H33 Retinal detachments and breaks
0.839 0.161 0.000
Chapter X Diseases of the respiratory system
0.837 0.163 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.837 0.163 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.836 0.164 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.832 0.168 0.000
I42 Cardiomyopathy
0.832 0.168 0.000
I44.2 Atrioventricular block, complete
0.831 0.169 0.000
I45.6 Preexcitation syndrome
0.831 0.169 0.000
E20-E35 Disorders of other endocrine glands
0.830 0.170 0.000
E14 Unspecified diabetes mellitus
0.829 0.171 0.000
N25-N29 Other disorders of kidney and ureter
0.828 0.172 0.000
Y43 Primarily systemic agents
0.828 0.172 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.826 0.174 0.000
M24 Other specific joint derangements
0.825 0.175 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.825 0.175 0.000
H52.1 Myopia
0.821 0.179 0.000
E16.2 Hypoglycaemia, unspecified
0.821 0.179 0.000
N30 Cystitis
0.819 0.181 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.819 0.181 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.813 0.187 0.000
B35-B49 Mycoses
0.812 0.188 0.000
I44.7 Left bundle-branch block, unspecified
0.811 0.189 0.000
R54 Senility
0.811 0.189 0.000
K66.0 Peritoneal adhesions
0.811 0.189 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.810 0.190 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.810 0.190 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.809 0.191 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.809 0.191 0.000
R07.4 Chest pain, unspecified
0.809 0.191 0.000
K65 Peritonitis
0.808 0.192 0.000
K76.9 Liver disease, unspecified
0.807 0.193 0.000
H34 Retinal vascular occlusions
0.807 0.193 0.000
I49 Other cardiac arrhythmias
0.806 0.194 0.000
M86-M90 Other osteopathies
0.805 0.195 0.000
N13 Obstructive and reflux uropathy
0.803 0.197 0.000
M91-M94 Chondropathies
0.802 0.197 0.000
B99-B99 Other infectious diseases
0.800 0.200 0.000
F20 Schizophrenia
0.799 0.201 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.799 0.201 0.000
H10-H13 Disorders of conjunctiva
0.798 0.202 0.000
R40 Somnolence, stupor and coma
0.797 0.203 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.795 0.205 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.795 0.205 0.000
R01 Cardiac murmurs and other cardiac sounds
0.794 0.206 0.000
S00-S09 Injuries to the head
0.793 0.207 0.000
W00-W19 Falls
0.791 0.209 0.000
F10.0 Acute intoxication
0.790 0.210 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.789 0.211 0.000
K26 Duodenal ulcer
0.787 0.213 0.000
I30 Acute pericarditis
0.786 0.214 0.000
D69 Purpura and other haemorrhagic conditions
0.786 0.214 0.000
H60-H62 Diseases of external ear
0.785 0.215 0.000
H72 Perforation of tympanic membrane
0.783 0.217 0.000
Chapter VI Diseases of the nervous system
0.783 0.217 0.000
B15-B19 Viral hepatitis
0.783 0.217 0.000
D10-D36 Benign neoplasms
0.782 0.218 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.781 0.219 0.000
D51 Vitamin B12 deficiency anaemia
0.780 0.220 0.000
K29 Gastritis and duodenitis
0.780 0.220 0.000
E13 Other specified diabetes mellitus
0.779 0.221 0.000
K25 Gastric ulcer
0.777 0.223 0.000
R59 Enlarged lymph nodes
0.777 0.223 0.000
I38 Endocarditis, valve unspecified
0.777 0.223 0.000
Y44 Agents primarily affecting blood constituents
0.777 0.223 0.000
I31 Other diseases of pericardium
0.775 0.225 0.000
I21 Acute myocardial infarction
0.775 0.225 0.000
S40-S49 Injuries to the shoulder and upper arm
0.774 0.226 0.000
A80-A89 Viral infections of the central nervous system
0.773 0.226 0.000
F30-F39 Mood [affective] disorders
0.773 0.227 0.000
N35 Urethral stricture
0.771 0.229 0.000
F60-F69 Disorders of adult personality and behaviour
0.770 0.230 0.000
H43-H45 Disorders of vitreous body and globe
0.769 0.231 0.000
M47.9 Spondylosis, unspecified
0.769 0.231 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
K08.3 Retained dental root
0.768 0.232 0.000
H53.0 Amblyopia ex anopsia
0.767 0.233 0.000
Chapter XXII Codes for special purposes
0.767 0.233 0.000
F41.9 Anxiety disorder, unspecified
0.767 0.233 0.000
H35.3 Degeneration of macula and posterior pole
0.766 0.234 0.000
N72 Inflammatory disease of cervix uteri
0.766 0.234 0.000
H36 Retinal disorders in diseases classified elsewhere
0.766 0.234 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.766 0.234 0.000
K70.9 Alcoholic liver disease, unspecified
0.764 0.236 0.000
D80-D89 Certain disorders involving the immune mechanism
0.764 0.236 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.763 0.237 0.000
Y52 Agents primarily affecting the cardiovascular system
0.763 0.237 0.000
R52.1 Chronic intractable pain
0.762 0.238 0.000
E11.9 Without complications
0.762 0.238 0.000
H35.0 Background retinopathy and retinal vascular changes
0.761 0.239 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.761 0.239 0.000
M35.3 Polymyalgia rheumatica
0.759 0.241 0.000
K00 Disorders of tooth development and eruption
0.759 0.241 0.000
Y57 Other and unspecified drugs and medicaments
0.758 0.242 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.758 0.242 0.000
K30 Dyspepsia
0.758 0.242 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.756 0.244 0.000
E14.3 With ophthalmic complications
0.756 0.244 0.000
E78.2 Mixed hyperlipidaemia
0.755 0.244 0.000
Y40 Systemic antibiotics
0.755 0.245 0.000
H33.0 Retinal detachment with retinal break
0.755 0.245 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.754 0.246 0.000
I08 Multiple valve diseases
0.754 0.246 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.754 0.246 0.000
E86 Volume depletion
0.753 0.247 0.000
I22 Subsequent myocardial infarction
0.753 0.247 0.000
H52.0 Hypermetropia
0.753 0.247 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.753 0.247 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.753 0.247 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.752 0.248 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.751 0.249 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.751 0.249 0.000
N00-N08 Glomerular diseases
0.751 0.249 0.000
K02.8 Other dental caries
0.750 0.250 0.000
I46.9 Cardiac arrest, unspecified
0.750 0.250 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.750 0.250 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.750 0.250 0.000
H35.6 Retinal haemorrhage
0.749 0.251 0.000
H35.8 Other specified retinal disorders
0.749 0.251 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.748 0.252 0.000
R56 Convulsions, not elsewhere classified
0.747 0.253 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.745 0.255 0.000
M21 Other acquired deformities of limbs
0.744 0.256 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.744 0.256 0.000
I20.1 Angina pectoris with documented spasm
0.743 0.257 0.000
K76.8 Other specified diseases of liver
0.742 0.258 0.000
F41.1 Generalised anxiety disorder
0.742 0.258 0.000
F10.4 Withdrawal state with delirium
0.742 0.258 0.000
I60 Subarachnoid haemorrhage
0.741 0.259 0.000
S50-S59 Injuries to the elbow and forearm
0.741 0.259 0.000
E11.1 With ketoacidosis
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
I10-I15 Hypertensive diseases
0.739 0.261 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.738 0.262 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.736 0.264 0.000
Z72 Problems related to lifestyle
0.736 0.264 0.000
K11 Diseases of salivary glands
0.734 0.266 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.734 0.266 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.733 0.267 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.732 0.268 0.000
K70.3 Alcoholic cirrhosis of liver
0.732 0.268 0.000
K10 Other diseases of jaws
0.731 0.269 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.730 0.269 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.731 0.269 0.000
K76.6 Portal hypertension
0.730 0.270 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.730 0.270 0.000
I46.0 Cardiac arrest with successful resuscitation
0.730 0.270 0.000
M31 Other necrotising vasculopathies
0.730 0.270 0.000
Y42.7 Androgens and anabolic congeners
0.730 0.270 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.729 0.270 0.000
Y84.8 Other medical procedures
0.729 0.271 0.000
N30.9 Cystitis, unspecified
0.729 0.271 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.729 0.271 0.000
K29.6 Other gastritis
0.727 0.273 0.000
D32 Benign neoplasm of meninges
0.727 0.273 0.000
J09-J18 Influenza and pneumonia
0.726 0.274 0.000
R52.9 Pain, unspecified
0.725 0.275 0.000
I42.0 Dilated cardiomyopathy
0.724 0.276 0.000
F40 Phobic anxiety disorders
0.724 0.276 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.722 0.277 0.000
J90-J94 Other diseases of pleura
0.722 0.278 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.721 0.279 0.000
N28.1 Cyst of kidney, acquired
0.721 0.279 0.000
E07 Other disorders of thyroid
0.719 0.281 0.000
F41.2 Mixed anxiety and depressive disorder
0.719 0.281 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.718 0.282 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.718 0.282 0.000
R57 Shock, not elsewhere classified
0.718 0.282 0.000
W20-W49 Exposure to inanimate mechanical forces
0.717 0.282 0.000
K29.1 Other acute gastritis
0.717 0.283 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.283 0.000
H57 Other disorders of eye and adnexa
0.716 0.284 0.000
K14 Diseases of tongue
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
R61 Hyperhidrosis
0.715 0.285 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
R00 Abnormalities of heart beat
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.285 0.000
M65-M68 Disorders of synovium and tendon
0.715 0.285 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.285 0.000
R04 Haemorrhage from respiratory passages
0.715 0.285 0.000
I67 Other cerebrovascular diseases
0.714 0.286 0.000
N30.2 Other chronic cystitis
0.714 0.286 0.000
H18 Other disorders of cornea
0.714 0.286 0.000
E11.5 With peripheral circulatory complications
0.714 0.286 0.000
E78.8 Other disorders of lipoprotein metabolism
0.713 0.287 0.000
E78.6 Lipoprotein deficiency
0.713 0.287 0.000
E78.4 Other hyperlipidaemia
0.713 0.287 0.000
E78.3 Hyperchylomicronaemia
0.713 0.287 0.000
E78.1 Pure hyperglyceridaemia
0.713 0.287 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.713 0.287 0.000
M47.1 Other spondylosis with myelopathy
0.712 0.287 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.712 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.711 0.288 0.000
M35.0 Sicca syndrome [Sjogren]
0.711 0.289 0.000
K01 Embedded and impacted teeth
0.711 0.289 0.000
F99-F99 Unspecified mental disorder
0.711 0.289 0.000
E11.3 With ophthalmic complications
0.710 0.290 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.710 0.290 0.000
R45 Symptoms and signs involving emotional state
0.709 0.291 0.000
M80 Osteoporosis with pathological fracture
0.709 0.291 0.000
N35.9 Urethral stricture, unspecified
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
K31 Other diseases of stomach and duodenum
0.709 0.291 0.000
E05.9 Thyrotoxicosis, unspecified
0.709 0.291 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.708 0.292 0.000
M23.9 Internal derangement of knee, unspecified
0.708 0.292 0.000
M23.5 Chronic instability of knee
0.708 0.292 0.000
M23.1 Discoid meniscus (congenital)
0.708 0.292 0.000
M23.0 Cystic meniscus
0.708 0.292 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.708 0.292 0.000
R09.0 Asphyxia
0.707 0.292 0.000
M23.4 Loose body in knee
0.707 0.293 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.707 0.293 0.000
R62 Lack of expected normal physiological development
0.707 0.293 0.000
R64 Cachexia
0.707 0.293 0.000
R58 Haemorrhage, not elsewhere classified
0.707 0.293 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.707 0.293 0.000
I44.6 Other and unspecified fascicular block
0.706 0.294 0.000
I44.5 Left posterior fascicular block
0.706 0.294 0.000
I44.4 Left anterior fascicular block
0.706 0.294 0.000
I44.3 Other and unspecified atrioventricular block
0.706 0.294 0.000
M47.89 Other spondylosis (Site unspecified)
0.706 0.294 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.706 0.294 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.706 0.294 0.000
M47.84 Other spondylosis (Thoracic region)
0.706 0.294 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.706 0.294 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.706 0.294 0.000
Z04 Examination and observation for other reasons
0.705 0.295 0.000
Y43.3 Other antineoplastic drugs
0.705 0.295 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.705 0.295 0.000
K04 Diseases of pulp and periapical tissues
0.705 0.295 0.000
B07 Viral warts
0.705 0.295 0.000
M24.1 Other articular cartilage disorders
0.705 0.295 0.000
K77 Liver disorders in diseases classified elsewhere
0.704 0.295 0.000
K75 Other inflammatory liver diseases
0.704 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.704 0.295 0.000
K71 Toxic liver disease
0.704 0.295 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.704 0.296 0.000
M45 Ankylosing spondylitis
0.703 0.297 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.703 0.297 0.000
I27 Other pulmonary heart diseases
0.703 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.298 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.702 0.298 0.000
H31 Other disorders of choroid
0.702 0.298 0.000
H30 Chorioretinal inflammation
0.702 0.298 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.701 0.299 0.000
H61 Other disorders of external ear
0.701 0.299 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
I25.4 Coronary artery aneurysm
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.701 0.299 0.000
I63 Cerebral infarction
0.700 0.300 0.000
F10.3 Withdrawal state
0.700 0.300 0.000
J95-J99 Other diseases of the respiratory system
0.699 0.301 0.000
K03 Other diseases of hard tissues of teeth
0.699 0.301 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.699 0.301 0.000
I45.9 Conduction disorder, unspecified
0.698 0.302 0.000
I45.8 Other specified conduction disorders
0.698 0.302 0.000
I45.5 Other specified heart block
0.698 0.302 0.000
I45.4 Nonspecific intraventricular block
0.698 0.302 0.000
I45.3 Trifascicular block
0.698 0.302 0.000
I45.2 Bifascicular block
0.698 0.302 0.000
I45.0 Right fascicular block
0.698 0.302 0.000
K09 Cysts of oral region, not elsewhere classified
0.698 0.302 0.000
R53 Malaise and fatigue
0.698 0.302 0.000
M48.0 Spinal stenosis
0.697 0.303 0.000
D23 Other benign neoplasms of skin
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.695 0.305 0.000
Y58 Bacterial vaccines
0.695 0.305 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.695 0.305 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.695 0.305 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.695 0.305 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.695 0.305 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.695 0.305 0.000
Y48 Anaesthetics and therapeutic gases
0.695 0.305 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.695 0.305 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.695 0.305 0.000
F45 Somatoform disorders
0.694 0.306 0.000
K74.5 Biliary cirrhosis, unspecified
0.694 0.306 0.000
R40.0 Somnolence
0.694 0.306 0.000
R73.0 Abnormal glucose tolerance test
0.693 0.306 0.000
Y84.1 Kidney dialysis
0.692 0.308 0.000
M25 Other joint disorders, not elsewhere classified
0.692 0.308 0.000
K70.4 Alcoholic hepatic failure
0.691 0.309 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.690 0.310 0.000
M47.82 Other spondylosis (Cervical region)
0.690 0.310 0.000
K12 Stomatitis and related lesions
0.690 0.310 0.000
E83.3 Disorders of phosphorus metabolism
0.690 0.310 0.000
R94 Abnormal results of function studies
0.690 0.310 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.690 0.310 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.689 0.311 0.000
M23.37 Other meniscus derangements-Capsular lig
0.689 0.311 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.689 0.311 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.689 0.311 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.689 0.311 0.000
K65.8 Other peritonitis
0.689 0.311 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.689 0.311 0.000
E12 Malnutrition-related diabetes mellitus
0.688 0.312 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.688 0.312 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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