TreeWAS – Variant ID: rs7748270

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
E10.9 Without complications	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
D86 Sarcoidosis	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
M06.3 Rheumatoid nodule	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.000	1.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.000	1.000
D86.0 Sarcoidosis of lung	0.000	0.000	1.000
E11.9 Without complications	1.000	0.000	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.000	1.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
J32.9 Chronic sinusitis, unspecified	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
M06.0 Seronegative rheumatoid arthritis	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.999	0.001	0.000
J32 Chronic sinusitis	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.001	0.999
D69.6 Thrombocytopenia, unspecified	0.000	0.001	0.999
J30-J39 Other diseases of upper respiratory tract	0.999	0.001	0.000
M45 Ankylosing spondylitis	0.998	0.002	0.000
M06.34 Rheumatoid nodule (Hand)	0.998	0.002	0.000
M45-M49 Spondylopathies	0.998	0.002	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.998	0.002	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.998	0.002	0.000
L40 Psoriasis	0.998	0.002	0.000
N40 Hyperplasia of prostate	0.998	0.002	0.000
N40-N51 Diseases of male genital organs	0.997	0.003	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.997	0.003	0.000
D68 Other coagulation defects	0.000	0.003	0.997
M65-M68 Disorders of synovium and tendon	0.996	0.004	0.000
M65 Synovitis and tenosynovitis	0.995	0.005	0.000
E10.3 With ophthalmic complications	0.995	0.005	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.995	0.005	0.000
N48 Other disorders of penis	0.994	0.006	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.991	0.009	0.000
E10.1 With ketoacidosis	0.990	0.010	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.986	0.014	0.000
D50-D53 Nutritional anaemias	0.000	0.015	0.985
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.985	0.015	0.000
E10.4 With neurological complications	0.984	0.016	0.000
R31 Unspecified haematuria	0.984	0.016	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.984	0.016	0.000
K90 Intestinal malabsorption	0.001	0.017	0.983
L40.5 Arthropathic psoriasis	0.983	0.017	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.017	0.983
M20-M25 Other joint disorders	0.982	0.018	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.979	0.021	0.000
J33.8 Other polyp of sinus	0.978	0.022	0.000
K50 Crohn's disease [regional enteritis]	0.978	0.022	0.000
M35.3 Polymyalgia rheumatica	0.977	0.023	0.000
K50.8 Other Crohn's disease	0.977	0.023	0.000
M35 Other systemic involvement of connective tissue	0.975	0.024	0.002
L40-L45 Papulosquamous disorders	0.975	0.025	0.000
N48.6 Balanitis xerotica obliterans	0.973	0.027	0.000
J33.0 Polyp of nasal cavity	0.972	0.028	0.000
N48.0 Leukoplakia of penis	0.970	0.030	0.000
K50.9 Crohn's disease, unspecified	0.970	0.030	0.000
J35 Chronic diseases of tonsils and adenoids	0.968	0.032	0.000
D69.4 Other primary thrombocytopenia	0.000	0.032	0.968
M07 Psoriatic and enteropathic arthropathies	0.967	0.033	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.966	0.034	0.000
D52 Folate deficiency anaemia	0.000	0.036	0.964
K50.1 Crohn's disease of large intestine	0.960	0.040	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.959	0.041	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.957	0.043	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.957	0.043	0.000
D68.5 Primary Thrombophilia	0.000	0.043	0.957
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.956	0.044	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.810	0.044	0.145
E10.5 With peripheral circulatory complications	0.955	0.045	0.000
N42 Other disorders of prostate	0.954	0.046	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.954	0.046	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.047	0.953
D52.9 Folate deficiency anaemia, unspecified	0.000	0.051	0.949
L43 Lichen planus	0.948	0.052	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.947	0.053	0.000
M20 Acquired deformities of fingers and toes	0.947	0.053	0.000
E10.8 With unspecified complications	0.946	0.054	0.000
M07.3 Other psoriatic arthropathies	0.945	0.055	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.944	0.056	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.059	0.941
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.940	0.060	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.938	0.062	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.065	0.935
J35.8 Other chronic diseases of tonsils and adenoids	0.934	0.066	0.000
E11.1 With ketoacidosis	0.933	0.067	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.930	0.070	0.000
N42.8 Other specified disorders of prostate	0.930	0.070	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.924	0.076	0.000
E13 Other specified diabetes mellitus	0.923	0.077	0.000
J45.9 Asthma, unspecified	0.920	0.080	0.000
D68.8 Other specified coagulation defects	0.000	0.082	0.918
N49.2 Inflammatory disorders of scrotum	0.918	0.082	0.000
J35.1 Hypertrophy of tonsils	0.917	0.083	0.000
N42.2 Atrophy of prostate	0.908	0.092	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.092	0.908
E10.6 With other specified complications	0.904	0.096	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.096	0.904
M30 Polyarteritis nodosa and related conditions	0.900	0.100	0.000
L43.9 Lichen planus, unspecified	0.899	0.101	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.104	0.896
M20.5 Other deformities of toe(s) (acquired)	0.896	0.104	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.896	0.104	0.000
N48.9 Disorder of penis, unspecified	0.895	0.105	0.000
M31 Other necrotising vasculopathies	0.895	0.105	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.892	0.108	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.109	0.891
J32.4 Chronic pansinusitis	0.888	0.112	0.000
D68.9 Coagulation defect, unspecified	0.000	0.113	0.887
M25 Other joint disorders, not elsewhere classified	0.887	0.113	0.000
M25.4 Effusion of joint	0.886	0.114	0.000
M25.46 Effusion of joint (Lower leg)	0.886	0.114	0.000
C82.0 Small cleaved cell, follicular	0.885	0.114	0.000
J45 Asthma	0.882	0.118	0.000
J32.1 Chronic frontal sinusitis	0.881	0.119	0.000
Chapter X Diseases of the respiratory system	0.870	0.130	0.000
J40-J47 Chronic lower respiratory diseases	0.869	0.131	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.137	0.863
M07.39 Other psoriatic arthropathies (Site unspecified)	0.863	0.137	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.139	0.861
M14 Arthropathies in other diseases classified elsewhere	0.860	0.140	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.857	0.143	0.000
M20.1 Hallux valgus (acquired)	0.852	0.148	0.000
M31.6 Other giant cell arteritis	0.851	0.149	0.000
M00-M03 Infectious arthropathies	0.849	0.151	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.847	0.153	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.153	0.847
E13.9 Without complications	0.844	0.156	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.844	0.156	0.000
K50.0 Crohn's disease of small intestine	0.844	0.156	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.841	0.159	0.000
D68.0 Von Willebrand's disease	0.000	0.159	0.841
M05.8 Other seropositive rheumatoid arthritis	0.839	0.161	0.000
C82.3 Follicular lymphoma grade IIIa	0.834	0.166	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.833	0.167	0.000
D69.0 Allergic purpura	0.000	0.169	0.831
M46 Other inflammatory spondylopathies	0.826	0.174	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.826	0.174	0.000
K90.8 Other intestinal malabsorption	0.000	0.177	0.823
M06.30 Rheumatoid nodule (Multiple sites)	0.820	0.180	0.000
# Top node	0.817	0.182	0.001
Chapter XII Diseases of the skin and subcutaneous tissue	0.817	0.183	0.000
J33.1 Polypoid sinus degeneration	0.815	0.185	0.000
E11.0 With coma	0.813	0.187	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.810	0.190	0.000
M06.33 Rheumatoid nodule (Forearm)	0.809	0.191	0.000
D55-D59 Haemolytic anaemias	0.000	0.191	0.809
M05.1 Rheumatoid lung disease	0.808	0.192	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.807	0.193	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.807	0.193	0.000
N48.5 Ulcer of penis	0.806	0.194	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.806	0.194	0.000
M06.4 Inflammatory polyarthropathy	0.804	0.196	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.198	0.802
J32.2 Chronic ethmoidal sinusitis	0.798	0.202	0.000
M08 Juvenile arthritis	0.792	0.208	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.792	0.208	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.789	0.210	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.716	0.211	0.074
L43.0 Hypertrophic lichen planus	0.789	0.211	0.000
E78.0 Pure hypercholesterolaemia	0.789	0.211	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.788	0.212	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.785	0.215	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.785	0.215	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.784	0.216	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.217	0.783
M14.6 Neuropathic arthropathy	0.781	0.219	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.779	0.221	0.000
M25.40 Effusion of joint (Multiple sites)	0.776	0.224	0.000
J46 Status asthmaticus	0.775	0.225	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.227	0.773
L02 Cutaneous abscess, furuncle and carbuncle	0.772	0.228	0.000
L43.8 Other lichen planus	0.770	0.230	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.231	0.769
M66 Spontaneous rupture of synovium and tendon	0.768	0.231	0.000
M06.8 Other specified rheumatoid arthritis	0.767	0.233	0.000
D86.3 Sarcoidosis of skin	0.000	0.233	0.767
D68.4 Acquired coagulation factor deficiency	0.000	0.234	0.766
M46.1 Sacro-iliitis, not elsewhere classified	0.758	0.242	0.000
E11.6 With other specified complications	0.757	0.243	0.000
C82.4 Follicular lymphoma grade IIIb	0.756	0.244	0.000
J35.2 Hypertrophy of adenoids	0.756	0.244	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.756	0.244	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.754	0.246	0.000
C82.2 Large cell, follicular	0.753	0.246	0.000
E10.0 With coma	0.753	0.247	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.750	0.249	0.000
M12 Other specific arthropathies	0.747	0.253	0.000
L40.4 Guttate psoriasis	0.747	0.253	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.744	0.256	0.000
M00 Pyogenic arthritis	0.744	0.256	0.000
M65.1 Other infective (teno)synovitis	0.741	0.258	0.000
E11.8 With unspecified complications	0.741	0.259	0.000
E14 Unspecified diabetes mellitus	0.740	0.260	0.000
M31.7 Microscopic polyangiitis	0.739	0.261	0.000
M07.38 Other psoriatic arthropathies (Other)	0.739	0.261	0.000
E13.3 With ophthalmic complications	0.738	0.262	0.000
M11 Other crystal arthropathies	0.738	0.262	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.737	0.263	0.000
L05 Pilonidal cyst	0.737	0.263	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.736	0.264	0.000
L40.1 Generalised pustular psoriasis	0.734	0.266	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.269	0.731
D59 Acquired haemolytic anaemia	0.000	0.270	0.730
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.725	0.275	0.000
M20.0 Deformity of finger(s)	0.724	0.276	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.723	0.277	0.000
N48.2 Other inflammatory disorders of penis	0.722	0.278	0.000
N42.3 Dysplasia of prostate	0.721	0.279	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.280	0.720
M65.2 Calcific tendinitis	0.718	0.282	0.000
J09-J18 Influenza and pneumonia	0.718	0.282	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.717	0.283	0.000
M06.38 Rheumatoid nodule (Other)	0.717	0.283	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.717	0.283	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.283	0.717
E11.7 With multiple complications	0.717	0.283	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.717	0.283	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.717	0.283	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
M49 Spondylopathies in diseases classified elsewhere	0.717	0.283	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.716	0.284	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.716	0.284	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.716	0.284	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.716	0.284	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.716	0.284	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.716	0.284	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.716	0.284	0.000
L40.2 Acrodermatitis continua	0.715	0.285	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.285	0.715
L05.0 Pilonidal cyst with abscess	0.715	0.285	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.714	0.285	0.000
M65.0 Abscess of tendon sheath	0.714	0.286	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.713	0.287	0.000
E05.8 Other thyrotoxicosis	0.000	0.291	0.709
L41 Parapsoriasis	0.708	0.291	0.000
K90.3 Pancreatic steatorrhoea	0.001	0.295	0.705
K90.2 Blind loop syndrome, not elsewhere classified	0.001	0.295	0.705
K90.1 Tropical sprue	0.001	0.295	0.705
D89.3 Immune reconstitution syndrome	0.000	0.295	0.705
M30.8 Other conditions related to polyarteritis nodosa	0.704	0.296	0.000
E40-E46 Malnutrition	0.629	0.296	0.075
C82.6 Cutaneous follicle centre lymphoma	0.702	0.298	0.000
C82.5 Diffuse follicle centre lymphoma	0.702	0.298	0.000
D89.1 Cryoglobulinaemia	0.000	0.300	0.700
M35.9 Systemic involvement of connective tissue, unspecified	0.699	0.300	0.001
M35.6 Relapsing panniculitis [Weber-Christian]	0.699	0.300	0.001
M35.5 Multifocal fibrosclerosis	0.699	0.300	0.001
M35.4 Diffuse (eosinophilic) fasciitis	0.699	0.300	0.001
D68.6 Other Thrombophilia	0.000	0.300	0.700
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.301	0.699
L45 Papulosquamous disorders in diseases classified elsewhere	0.699	0.301	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.698	0.302	0.000
L40.8 Other psoriasis	0.696	0.304	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.694	0.306	0.000
E10.7 With multiple complications	0.693	0.306	0.000
M07.5 Arthropathy in ulcerative colitis	0.693	0.307	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.693	0.307	0.000
M07.2 Psoriatic spondylitis	0.693	0.307	0.000
M07.1 Arthritis mutilans	0.693	0.307	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.693	0.307	0.000
M25.47 Effusion of joint (Ankle and foot)	0.692	0.308	0.000
D52.8 Other folate deficiency anaemias	0.000	0.309	0.691
D52.1 Drug-induced folate deficiency anaemia	0.000	0.309	0.691
D52.0 Dietary folate deficiency anaemia	0.000	0.309	0.691
M30.0 Polyarteritis nodosa	0.691	0.309	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.688	0.312	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.688	0.312	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.688	0.312	0.000
L44 Other papulosquamous disorders	0.687	0.313	0.000
D67 Hereditary factor IX deficiency	0.000	0.315	0.685
L40.3 Pustulosis palmaris et plantaris	0.684	0.315	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.316	0.682
L42 Pityriasis rosea	0.681	0.319	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.319	0.681
M25.6 Stiffness of joint, not elsewhere classified	0.680	0.320	0.000
D84 Other immunodeficiencies	0.000	0.320	0.680
L43.3 Subacute (active) lichen planus	0.680	0.320	0.000
L43.2 Lichenoid drug reaction	0.680	0.320	0.000
L43.1 Bullous lichen planus	0.680	0.320	0.000
M07.6 Other enteropathic arthropathies	0.678	0.322	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.322	0.678
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.678	0.322	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.677	0.322	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.677	0.322	0.000
E27 Other disorders of adrenal gland	0.000	0.323	0.677
T36-T50 Poisoning by drugs, medicaments and biological substances	0.677	0.323	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.676	0.324	0.000
D51.2 Transcobalamin II deficiency	0.000	0.325	0.675
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.325	0.675
M31.4 Aortic arch syndrome [Takayasu]	0.674	0.326	0.000
E10.2 With renal complications	0.673	0.326	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.672	0.328	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.329	0.671
M20.4 Other hammer toe(s) (acquired)	0.670	0.330	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.670	0.330	0.000
J42 Unspecified chronic bronchitis	0.670	0.330	0.000
E16 Other disorders of pancreatic internal secretion	0.648	0.330	0.022
M05.2 Rheumatoid vasculitis	0.670	0.330	0.000
L40.0 Psoriasis vulgaris	0.670	0.330	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.667	0.333	0.000
M65.8 Other synovitis and tenosynovitis	0.667	0.333	0.000
N44 Torsion of testis	0.665	0.335	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.665	0.335	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.337	0.663
E13.8 With unspecified complications	0.661	0.338	0.000
E13.7 With multiple complications	0.661	0.338	0.000
E13.6 With other specified complications	0.661	0.338	0.000
E13.5 With peripheral circulatory complications	0.661	0.338	0.000
E13.4 With neurological complications	0.661	0.338	0.000
E13.2 With renal complications	0.661	0.338	0.000
E13.1 With ketoacidosis	0.661	0.338	0.000
E13.0 With coma	0.661	0.338	0.000
M25.8 Other specified joint disorders	0.661	0.339	0.000
E14.6 With other specified complications	0.660	0.340	0.000
M66.3 Spontaneous rupture of flexor tendons	0.659	0.341	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.658	0.342	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.658	0.342	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.658	0.342	0.000
M35.1 Other overlap syndromes	0.655	0.344	0.001
M35.8 Other specified systemic involvement of connective tissue	0.654	0.344	0.001
J45.1 Nonallergic asthma	0.654	0.346	0.000
D69.1 Qualitative platelet defects	0.000	0.346	0.653
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.652	0.348	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.349	0.651
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.645	0.355	0.000
M30.2 Juvenile polyarteritis	0.645	0.355	0.000
J32.0 Chronic maxillary sinusitis	0.644	0.356	0.000
M08.0 Juvenile rheumatoid arthritis	0.643	0.356	0.000
M14.2 Diabetic arthropathy	0.643	0.356	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.642	0.358	0.000
M31.2 Lethal midline granuloma	0.642	0.358	0.000
S32.50 Fracture of pubis (closed)	0.640	0.360	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.640	0.360	0.000
N48.3 Priapism	0.638	0.361	0.000
M25.2 Flail joint	0.636	0.364	0.000
M25.1 Fistula of joint	0.636	0.364	0.000
M00.9 Pyogenic arthritis, unspecified	0.636	0.364	0.000
M25.49 Effusion of joint (Site unspecified)	0.635	0.365	0.000
M25.48 Effusion of joint (Other)	0.635	0.365	0.000
S32.5 Fracture of pubis	0.635	0.365	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.634	0.366	0.000
M31.9 Necrotising vasculopathy, unspecified	0.633	0.367	0.000
J45.8 Mixed asthma	0.633	0.367	0.000
J43 Emphysema	0.632	0.368	0.000
S32 Fracture of lumbar spine and pelvis	0.632	0.368	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.632	0.368	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.630	0.369	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.630	0.370	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.629	0.371	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.629	0.371	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.628	0.372	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.627	0.373	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.626	0.374	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.374	0.626
M45.X6 Ankylosing spondylitis (Lumbar region)	0.625	0.374	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.624	0.376	0.000
M86-M90 Other osteopathies	0.622	0.377	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.622	0.378	0.000
J32.3 Chronic sphenoidal sinusitis	0.621	0.378	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.621	0.379	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.620	0.380	0.000
M31.8 Other specified necrotising vasculopathies	0.619	0.381	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.619	0.381	0.000
N48.1 Balanoposthitis	0.619	0.381	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.618	0.382	0.000
M14.4 Arthropathy in amyloidosis	0.616	0.383	0.000
M14.3 Lipoid dermatoarthritis	0.616	0.383	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.616	0.383	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.616	0.383	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.384	0.615
M11.2 Other chondrocalcinosis	0.615	0.385	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.614	0.386	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.614	0.386	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.614	0.386	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.614	0.386	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.614	0.386	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.614	0.386	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.614	0.386	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.614	0.386	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.613	0.387	0.000
E11.5 With peripheral circulatory complications	0.612	0.388	0.000
T38.1 Thyroid hormones and substitutes	0.610	0.389	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.609	0.391	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.609	0.391	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.606	0.394	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.606	0.394	0.000
J37 Chronic laryngitis and laryngotracheitis	0.603	0.397	0.000
M25.41 Effusion of joint (Shoulder region)	0.602	0.398	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.602	0.398	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.602	0.398	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.602	0.398	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.602	0.398	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.602	0.398	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.602	0.398	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.602	0.398	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.602	0.398	0.000
M02 Reactive arthropathies	0.601	0.399	0.000
J41 Simple and mucopurulent chronic bronchitis	0.599	0.401	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.597	0.402	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.597	0.403	0.000
E16.2 Hypoglycaemia, unspecified	0.593	0.406	0.001
E20-E35 Disorders of other endocrine glands	0.008	0.407	0.585
M46.8 Other specified inflammatory spondylopathies	0.592	0.407	0.000
M46.5 Other infective spondylopathies	0.592	0.407	0.000
L04 Acute lymphadenitis	0.592	0.408	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.409	0.591
E27.2 Addisonian crisis	0.000	0.409	0.590
D83 Common variable immunodeficiency	0.000	0.410	0.589
N48.4 Impotence of organic origin	0.589	0.411	0.000
M25.44 Effusion of joint (Hand)	0.589	0.411	0.000
M66.2 Spontaneous rupture of extensor tendons	0.588	0.412	0.000
M35.2 Behcet's disease	0.586	0.412	0.001
D66 Hereditary factor VIII deficiency	0.000	0.413	0.587
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.586	0.414	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.584	0.416	0.000
M46.2 Osteomyelitis of vertebra	0.583	0.417	0.000
E14.0 With coma	0.581	0.419	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.581	0.419	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.580	0.420	0.001
D55 Anaemia due to enzyme disorders	0.000	0.420	0.580
M25.42 Effusion of joint (Upper arm)	0.580	0.420	0.000
M05.18 Rheumatoid lung disease (Other)	0.579	0.421	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.579	0.421	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.579	0.421	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.579	0.421	0.000
M05.14 Rheumatoid lung disease (Hand)	0.579	0.421	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.579	0.421	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.579	0.421	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.579	0.421	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.579	0.421	0.000
M25.43 Effusion of joint (Forearm)	0.579	0.421	0.000
J12 Viral pneumonia, not elsewhere classified	0.579	0.421	0.000
M60-M63 Disorders of muscles	0.578	0.422	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.576	0.423	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.576	0.423	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.576	0.423	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.576	0.423	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.576	0.423	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.576	0.423	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.576	0.423	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.426	0.574
E11.4 With neurological complications	0.574	0.426	0.000
M46.0 Spinal enthesopathy	0.571	0.429	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.571	0.429	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.570	0.430	0.000
M08.9 Juvenile arthritis, unspecified	0.568	0.432	0.000
M08.8 Other juvenile arthritis	0.568	0.432	0.000
M08.4 Pauciarticular juvenile arthritis	0.568	0.432	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.568	0.432	0.000
M08.2 Juvenile arthritis with systemic onset	0.568	0.432	0.000
M08.1 Juvenile ankylosing spondylitis	0.568	0.432	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.566	0.434	0.000
E15 Nondiabetic hypoglycaemic coma	0.513	0.434	0.053
L00 Staphylococcal scalded skin syndrome	0.565	0.435	0.000
M25.9 Joint disorder, unspecified	0.564	0.435	0.000
M12.3 Palindromic rheumatism	0.564	0.436	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.562	0.437	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.562	0.438	0.000
D57 Sickle-cell disorders	0.000	0.439	0.561
M88 Paget's disease of bone [osteitis deformans]	0.560	0.440	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.560	0.440	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.559	0.440	0.000
D56 Thalassaemia	0.000	0.441	0.559
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.556	0.443	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.556	0.444	0.000
M31.1 Thrombotic microangiopathy	0.555	0.444	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations