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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77492256
log Bayes Factor = 13.3135
Chromosome 2   position 180,294,914  (GRCh37) Explore rs77492256 on Ensembl!
Variant rs77492256 is part of Cluster X0170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
I20 Angina pectoris
0.991 0.009 0.000
B95-B98 Bacterial, viral and other infectious agents
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
T81 Complications of procedures, not elsewhere classified
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
M23 Internal derangement of knee
0.985 0.015 0.000
M20 Acquired deformities of fingers and toes
0.983 0.017 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.981 0.019 0.000
I20.9 Angina pectoris, unspecified
0.979 0.021 0.000
I25 Chronic ischaemic heart disease
0.974 0.026 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.969 0.031 0.000
M20.5 Other deformities of toe(s) (acquired)
0.953 0.047 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.948 0.052 0.000
M70-M79 Other soft tissue disorders
0.946 0.054 0.000
T66-T78 Other and unspecified effects of external causes
0.943 0.057 0.000
H25-H28 Disorders of lens
0.943 0.057 0.000
I30-I52 Other forms of heart disease
0.942 0.058 0.000
M25 Other joint disorders, not elsewhere classified
0.937 0.063 0.000
Chapter VIII Diseases of the ear and mastoid process
0.935 0.065 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.933 0.067 0.000
M22 Disorders of patella
0.930 0.070 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.929 0.071 0.000
Chapter VI Diseases of the nervous system
0.929 0.071 0.000
H25 Senile cataract
0.928 0.072 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.925 0.075 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.921 0.079 0.000
H25.1 Senile nuclear cataract
0.918 0.082 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.918 0.082 0.000
I20.8 Other forms of angina pectoris
0.917 0.083 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.914 0.086 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.906 0.094 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.906 0.094 0.000
T78 Adverse effects, not elsewhere classified
0.903 0.097 0.000
M23.3 Other meniscus derangements
0.902 0.098 0.000
H53-H54 Visual disturbances and blindness
0.901 0.099 0.000
M20.4 Other hammer toe(s) (acquired)
0.899 0.101 0.000
M25.7 Osteophyte
0.897 0.103 0.000
S60-S69 Injuries to the wrist and hand
0.896 0.104 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.895 0.105 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.891 0.109 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.889 0.111 0.000
M77 Other enthesopathies
0.889 0.111 0.000
Chapter XXII Codes for special purposes
0.887 0.113 0.000
W00-W19 Falls
0.883 0.117 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.883 0.117 0.000
I44 Atrioventricular and left bundle-branch block
0.876 0.124 0.000
M05-M14 Inflammatory polyarthropathies
0.871 0.129 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.864 0.136 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.864 0.136 0.000
I21 Acute myocardial infarction
0.861 0.139 0.000
B25-B34 Other viral diseases
0.861 0.139 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.859 0.141 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.859 0.141 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.856 0.144 0.000
M25.77 Osteophyte (Ankle and foot)
0.852 0.148 0.000
M65-M68 Disorders of synovium and tendon
0.843 0.157 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.843 0.157 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.842 0.158 0.000
I31 Other diseases of pericardium
0.840 0.160 0.000
G20-G26 Extrapyramidal and movement disorders
0.840 0.160 0.000
Y83.6 Removal of other organ (partial) (total)
0.839 0.161 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.839 0.161 0.000
G90-G99 Other disorders of the nervous system
0.836 0.164 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.835 0.165 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.833 0.167 0.000
M22.8 Other disorders of patella
0.832 0.167 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.832 0.168 0.000
I60-I69 Cerebrovascular diseases
0.832 0.168 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.830 0.170 0.000
I44.2 Atrioventricular block, complete
0.829 0.171 0.000
B15-B19 Viral hepatitis
0.828 0.172 0.000
M21 Other acquired deformities of limbs
0.827 0.173 0.000
H52 Disorders of refraction and accommodation
0.823 0.177 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.821 0.179 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.820 0.180 0.000
S10-S19 Injuries to the neck
0.820 0.180 0.000
M86-M90 Other osteopathies
0.817 0.183 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.811 0.188 0.000
H53 Visual disturbances
0.809 0.191 0.000
M91-M94 Chondropathies
0.809 0.191 0.000
T78.4 Allergy, unspecified
0.804 0.195 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.799 0.201 0.000
H60-H62 Diseases of external ear
0.798 0.201 0.000
I35 Nonrheumatic aortic valve disorders
0.798 0.202 0.000
G93 Other disorders of brain
0.798 0.202 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.794 0.206 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.794 0.206 0.000
H90-H95 Other disorders of ear
0.794 0.206 0.000
M20.1 Hallux valgus (acquired)
0.794 0.206 0.000
T78.3 Angioneurotic oedema
0.793 0.207 0.000
O80-O84 Delivery
0.790 0.210 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.787 0.213 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.787 0.213 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.786 0.214 0.000
M24 Other specific joint derangements
0.786 0.214 0.000
B35-B49 Mycoses
0.785 0.215 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.783 0.217 0.000
H43-H45 Disorders of vitreous body and globe
0.783 0.217 0.000
Y86 Sequelae of other accidents
0.776 0.224 0.000
M60-M63 Disorders of muscles
0.775 0.225 0.000
H80-H83 Diseases of inner ear
0.774 0.226 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.771 0.229 0.000
I25.2 Old myocardial infarction
0.771 0.229 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.770 0.230 0.000
H25.8 Other senile cataract
0.769 0.231 0.000
D80-D89 Certain disorders involving the immune mechanism
0.768 0.232 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.767 0.233 0.000
B34 Viral infection of unspecified site
0.764 0.236 0.000
M77.1 Lateral epicondylitis
0.763 0.237 0.000
I20.1 Angina pectoris with documented spasm
0.762 0.237 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.761 0.239 0.000
S70-S79 Injuries to the hip and thigh
0.761 0.239 0.000
M23.4 Loose body in knee
0.760 0.240 0.000
T79-T79 Certain early complications of trauma
0.760 0.240 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.759 0.241 0.000
S61 Open wound of wrist and hand
0.754 0.246 0.000
I25.5 Ischaemic cardiomyopathy
0.750 0.249 0.000
W19 Unspecified fall
0.750 0.250 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.750 0.250 0.000
M31 Other necrotising vasculopathies
0.750 0.250 0.000
M77.4 Metatarsalgia
0.749 0.251 0.000
I71 Aortic aneurysm and dissection
0.746 0.254 0.000
H52.1 Myopia
0.746 0.254 0.000
S40-S49 Injuries to the shoulder and upper arm
0.746 0.254 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.745 0.255 0.000
O00-O08 Pregnancy with abortive outcome
0.744 0.256 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.743 0.257 0.000
M22.4 Chondromalacia patellae
0.742 0.258 0.000
I05-I09 Chronic rheumatic heart diseases
0.742 0.258 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.741 0.259 0.000
M22.2 Patellofemoral disorders
0.741 0.259 0.000
I31.3 Pericardial effusion (noninflammatory)
0.740 0.260 0.000
Y40 Systemic antibiotics
0.740 0.260 0.000
O60-O75 Complications of labour and delivery
0.739 0.261 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.738 0.262 0.000
M23.8 Other internal derangements of knee
0.738 0.262 0.000
M80-M85 Disorders of bone density and structure
0.738 0.262 0.000
G30-G32 Other degenerative diseases of the nervous system
0.737 0.263 0.000
G25 Other extrapyramidal and movement disorders
0.736 0.264 0.000
Y83.5 Amputation of limb(s)
0.735 0.265 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.735 0.265 0.000
Y83.4 Other reconstructive surgery
0.733 0.267 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.733 0.267 0.000
Chapter XIV Diseases of the genitourinary system
0.733 0.267 0.000
I33 Acute and subacute endocarditis
0.733 0.267 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.733 0.267 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.732 0.268 0.000
D70 Agranulocytosis
0.732 0.268 0.000
H54 Blindness and low vision
0.728 0.272 0.000
H55-H59 Other disorders of eye and adnexa
0.727 0.273 0.000
T78.2 Anaphylactic shock, unspecified
0.725 0.275 0.000
M77.0 Medial epicondylitis
0.723 0.277 0.000
H50 Other strabismus
0.721 0.279 0.000
G57 Mononeuropathies of lower limb
0.720 0.280 0.000
I22 Subsequent myocardial infarction
0.718 0.282 0.000
I45 Other conduction disorders
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.283 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.716 0.284 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.716 0.284 0.000
M79.1 Myalgia
0.715 0.285 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.715 0.285 0.000
T92 Sequelae of injuries of upper limb
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.713 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.286 0.000
B65-B83 Helminthiases
0.713 0.286 0.000
B50-B64 Protozoal diseases
0.713 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.286 0.000
A75-A79 Rickettsioses
0.713 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.286 0.000
A65-A69 Other spirochaetal diseases
0.713 0.286 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.286 0.000
A15-A19 Tuberculosis
0.713 0.286 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.713 0.287 0.000
S80-S89 Injuries to the knee and lower leg
0.711 0.289 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.710 0.290 0.000
X60-X84 Intentional self-harm
0.710 0.290 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
T81.9 Unspecified complication of procedure
0.709 0.291 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.709 0.291 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.709 0.291 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.709 0.291 0.000
S61.1 Open wound of finger(s) with damage to nail
0.709 0.291 0.000
I44.1 Atrioventricular block, second degree
0.708 0.292 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
O85-O92 Complications predominantly related to the puerperium
0.707 0.293 0.000
M65 Synovitis and tenosynovitis
0.707 0.293 0.000
I74 Arterial embolism and thrombosis
0.707 0.293 0.000
W17 Other fall from one level to another
0.706 0.294 0.000
M23.9 Internal derangement of knee, unspecified
0.706 0.294 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.706 0.294 0.000
M23.5 Chronic instability of knee
0.706 0.294 0.000
M23.1 Discoid meniscus (congenital)
0.706 0.294 0.000
M23.0 Cystic meniscus
0.706 0.294 0.000
H53.9 Visual disturbance, unspecified
0.705 0.295 0.000
M20.3 Other deformity of hallux (acquired)
0.705 0.295 0.000
H25.9 Senile cataract, unspecified
0.705 0.295 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.703 0.297 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.703 0.297 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.703 0.297 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.703 0.297 0.000
I24 Other acute ischaemic heart diseases
0.702 0.298 0.000
I44.0 Atrioventricular block, first degree
0.702 0.298 0.000
H10-H13 Disorders of conjunctiva
0.701 0.299 0.000
Y83.9 Surgical procedure, unspecified
0.701 0.299 0.000
M05 Seropositive rheumatoid arthritis
0.701 0.299 0.000
G93.3 Postviral fatigue syndrome
0.700 0.300 0.000
I25.6 Silent myocardial ischaemia
0.698 0.301 0.000
I25.4 Coronary artery aneurysm
0.698 0.301 0.000
I25.3 Aneurysm of heart
0.698 0.301 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.698 0.301 0.000
M20.0 Deformity of finger(s)
0.698 0.302 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.697 0.303 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.697 0.303 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.695 0.305 0.000
B34.9 Viral infection, unspecified
0.695 0.305 0.000
M25.76 Osteophyte (Lower leg)
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.305 0.000
S20-S29 Injuries to the thorax
0.694 0.306 0.000
G20 Parkinson's disease
0.693 0.307 0.000
I30 Acute pericarditis
0.691 0.309 0.000
N20-N23 Urolithiasis
0.690 0.310 0.000
M79.7 Fibromyalgia
0.690 0.310 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.688 0.312 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.688 0.312 0.000
D50-D53 Nutritional anaemias
0.687 0.313 0.000
I38 Endocarditis, valve unspecified
0.686 0.314 0.000
I35.8 Other aortic valve disorders
0.686 0.314 0.000
I73 Other peripheral vascular diseases
0.686 0.314 0.000
W20-W49 Exposure to inanimate mechanical forces
0.685 0.315 0.000
I60 Subarachnoid haemorrhage
0.685 0.315 0.000
T88.4 Failed or difficult intubation
0.684 0.316 0.000
D86 Sarcoidosis
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.682 0.318 0.000
M10 Gout
0.682 0.318 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.681 0.318 0.000
W06 Fall involving bed
0.681 0.319 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.681 0.319 0.000
H60 Otitis externa
0.681 0.319 0.000
S90-S99 Injuries to the ankle and foot
0.680 0.320 0.000
M71 Other bursopathies
0.679 0.321 0.000
M76 Enthesopathies of lower limb, excluding foot
0.678 0.322 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.678 0.322 0.000
S62 Fracture at wrist and hand level
0.677 0.323 0.000
I34 Nonrheumatic mitral valve disorders
0.677 0.323 0.000
N20 Calculus of kidney and ureter
0.676 0.324 0.000
T75 Effects of other external causes
0.676 0.324 0.000
T74 Maltreatment syndromes
0.676 0.324 0.000
T73 Effects of other deprivation
0.676 0.324 0.000
T70 Effects of air pressure and water pressure
0.676 0.324 0.000
T69 Other effects of reduced temperature
0.676 0.324 0.000
T67 Effects of heat and light
0.676 0.324 0.000
T71 Asphyxiation
0.676 0.324 0.000
T68 Hypothermia
0.676 0.324 0.000
T66 Unspecified effects of radiation
0.676 0.324 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.676 0.324 0.000
H27 Other disorders of lens
0.676 0.324 0.000
I52 Other heart disorders in diseases classified elsewhere
0.676 0.324 0.000
I48 Atrial fibrillation and flutter
0.676 0.324 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.676 0.324 0.000
I41 Myocarditis in diseases classified elsewhere
0.676 0.324 0.000
I40 Acute myocarditis
0.676 0.324 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.676 0.324 0.000
I37 Pulmonary valve disorders
0.676 0.324 0.000
I36 Nonrheumatic tricuspid valve disorders
0.676 0.324 0.000
I32 Pericarditis in diseases classified elsewhere
0.676 0.324 0.000
O80 Single spontaneous delivery
0.675 0.325 0.000
S69 Other and unspecified injuries of wrist and hand
0.674 0.326 0.000
H53.0 Amblyopia ex anopsia
0.674 0.326 0.000
L03 Cellulitis
0.673 0.327 0.000
G93.9 Disorder of brain, unspecified
0.673 0.327 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.673 0.327 0.000
M25.9 Joint disorder, unspecified
0.672 0.328 0.000
M25.8 Other specified joint disorders
0.672 0.328 0.000
M25.3 Other instability of joint
0.672 0.328 0.000
M25.2 Flail joint
0.672 0.328 0.000
M25.1 Fistula of joint
0.672 0.328 0.000
M25.0 Haemarthrosis
0.672 0.328 0.000
M94 Other disorders of cartilage
0.672 0.328 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.670 0.330 0.000
M77.9 Enthesopathy, unspecified
0.670 0.330 0.000
B18 Chronic viral hepatitis
0.670 0.330 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.330 0.000
M40-M43 Deforming dorsopathies
0.669 0.330 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.669 0.331 0.000
I31.9 Disease of pericardium, unspecified
0.667 0.333 0.000
M22.1 Recurrent subluxation of patella
0.667 0.333 0.000
M22.9 Disorder of patella, unspecified
0.667 0.333 0.000
M22.3 Other derangements of patella
0.667 0.333 0.000
M22.0 Recurrent dislocation of patella
0.667 0.333 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.667 0.333 0.000
G57.6 Lesion of plantar nerve
0.667 0.333 0.000
W19.9 Unspecified place
0.667 0.333 0.000
G70-G73 Diseases of myoneural junction and muscle
0.666 0.334 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.666 0.334 0.000
H25.2 Senile cataract, morgagnian type
0.665 0.335 0.000
M06 Other rheumatoid arthritis
0.665 0.335 0.000
Y83.0 Surgical operation with transplant of whole organ
0.663 0.337 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.663 0.337 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.662 0.338 0.000
N10-N16 Renal tubulo-interstitial diseases
0.662 0.338 0.000
S60 Superficial injury of wrist and hand
0.661 0.339 0.000
I61 Intracerebral haemorrhage
0.661 0.339 0.000
I42 Cardiomyopathy
0.660 0.340 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.660 0.340 0.000
H65-H75 Diseases of middle ear and mastoid
0.660 0.340 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.659 0.341 0.000
H04 Disorders of lachrymal system
0.659 0.341 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.658 0.342 0.000
I49 Other cardiac arrhythmias
0.658 0.342 0.000
M21.1 Varus deformity, not elsewhere classified
0.658 0.342 0.000
I47 Paroxysmal tachycardia
0.657 0.343 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.657 0.343 0.000
M21.3 Wrist or foot drop (acquired)
0.656 0.344 0.000
Q80-Q89 Other congenital malformations
0.656 0.344 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.655 0.345 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.655 0.345 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.655 0.345 0.000
G93.2 Benign intracranial hypertension
0.655 0.345 0.000
N20.0 Calculus of kidney
0.654 0.346 0.000
S64 Injury of nerves at wrist and hand level
0.654 0.346 0.000
M25.74 Osteophyte (Hand)
0.652 0.348 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.652 0.348 0.000
B17 Other acute viral hepatitis
0.651 0.349 0.000
H51 Other disorders of binocular movement
0.650 0.350 0.000
H49 Paralytic strabismus
0.650 0.350 0.000
M79.8 Other specified soft tissue disorders
0.650 0.350 0.000
I67 Other cerebrovascular diseases
0.650 0.350 0.000
D55-D59 Haemolytic anaemias
0.649 0.350 0.000
T82.3 Mechanical complication of other vascular grafts
0.649 0.351 0.000
I77 Other disorders of arteries and arterioles
0.649 0.351 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.648 0.351 0.000
S19 Other and unspecified injuries of neck
0.648 0.352 0.000
I63 Cerebral infarction
0.648 0.352 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.648 0.352 0.000
Q60-Q64 Congenital malformations of the urinary system
0.648 0.352 0.000
T78.9 Adverse effect, unspecified
0.647 0.353 0.000
T78.8 Other adverse effects, not elsewhere classified
0.647 0.353 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.647 0.353 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.647 0.353 0.000
M67 Other disorders of synovium and tendon
0.647 0.353 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.647 0.353 0.000
M23.37 Other meniscus derangements-Capsular lig
0.647 0.353 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.647 0.353 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.647 0.353 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.647 0.353 0.000
S10 Superficial injury of neck
0.646 0.354 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.645 0.355 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.645 0.355 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.645 0.355 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.645 0.355 0.000
H52.2 Astigmatism
0.644 0.355 0.000
H93 Other disorders of ear, not elsewhere classified
0.644 0.356 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.644 0.356 0.000
O82 Single delivery by Caesarean section
0.643 0.357 0.000
M25.79 Osteophyte (Site unspecified)
0.643 0.357 0.000
M25.73 Osteophyte (Forearm)
0.643 0.357 0.000
M25.72 Osteophyte (Upper arm)
0.643 0.357 0.000
M25.71 Osteophyte (Shoulder region)
0.643 0.357 0.000
M25.70 Osteophyte (Multiple sites)
0.643 0.357 0.000
U80 Agent resistant to penicillin and related antibiotics
0.643 0.357 0.000
S63.6 Sprain and strain of finger(s)
0.643 0.357 0.000
Y83.3 Surgical operation with formation of external stoma
0.642 0.358 0.000
S67 Crushing injury of wrist and hand
0.642 0.358 0.000
S65 Injury of blood vessels at wrist and hand level
0.642 0.358 0.000
M25.5 Pain in joint
0.642 0.358 0.000
H53.8 Other visual disturbances
0.641 0.359 0.000
W13 Fall from, out of or through building or structure
0.640 0.360 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.640 0.360 0.000
M13 Other arthritis
0.640 0.360 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.639 0.361 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.637 0.362 0.000
M77.5 Other enthesopathy of foot
0.637 0.362 0.000
M77.3 Calcaneal spur
0.637 0.362 0.000
M77.2 Periarthritis of wrist
0.637 0.362 0.000
M11 Other crystal arthropathies
0.637 0.363 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.636 0.364 0.000
H90 Conductive and sensorineural hearing loss
0.636 0.364 0.000
I70 Atherosclerosis
0.636 0.364 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.636 0.364 0.000
M07 Psoriatic and enteropathic arthropathies
0.634 0.366 0.000
B37 Candidiasis
0.634 0.366 0.000
W18 Other fall on same level
0.633 0.367 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.633 0.367 0.000
W15 Fall from cliff
0.633 0.367 0.000
W14 Fall from tree
0.633 0.367 0.000
W12 Fall on and from scaffolding
0.633 0.367 0.000
W11 Fall on and from ladder
0.633 0.367 0.000
W10 Fall on and from stairs and steps
0.633 0.367 0.000
W09 Fall involving playground equipment
0.633 0.367 0.000
W08 Fall involving other furniture
0.633 0.367 0.000
W07 Fall involving chair
0.633 0.367 0.000
W05 Fall involving wheelchair
0.633 0.367 0.000
W04 Fall while being carried or supported by other persons
0.633 0.367 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.633 0.367 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.633 0.367 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.633 0.367 0.000
W00 Fall on same level involving ice and snow
0.633 0.367 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.633 0.367 0.000
I72 Other aneurysm
0.633 0.367 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.633 0.367 0.000
M90 Osteopathies in diseases classified elsewhere
0.632 0.367 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.632 0.368 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.629 0.371 0.000
I44.6 Other and unspecified fascicular block
0.628 0.372 0.000
I44.5 Left posterior fascicular block
0.628 0.372 0.000
I44.4 Left anterior fascicular block
0.628 0.372 0.000
I44.3 Other and unspecified atrioventricular block
0.628 0.372 0.000
H83 Other diseases of inner ear
0.628 0.372 0.000
G51 Facial nerve disorders
0.627 0.373 0.000
G30 Alzheimer's disease
0.626 0.374 0.000
L40-L45 Papulosquamous disorders
0.626 0.374 0.000
M89 Other disorders of bone
0.625 0.374 0.000
T93 Sequelae of injuries of lower limb
0.625 0.375 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.624 0.375 0.000
M14 Arthropathies in other diseases classified elsewhere
0.624 0.376 0.000
M12 Other specific arthropathies
0.624 0.376 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.624 0.376 0.000
M08 Juvenile arthritis
0.624 0.376 0.000
I25.1 Atherosclerotic heart disease
0.624 0.376 0.000
S68 Traumatic amputation of wrist and hand
0.623 0.377 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.622 0.377 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.622 0.378 0.000
G93.6 Cerebral oedema
0.621 0.379 0.000
M25.4 Effusion of joint
0.621 0.379 0.000
U89 Agent resistant to other and unspecified antibiotics
0.620 0.380 0.000
Y89 Sequelae of other external causes
0.619 0.380 0.000
Y88 Sequelae of surgical and medical care as external cause
0.619 0.380 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.619 0.380 0.000
Y85 Sequelae of transport accidents
0.619 0.380 0.000
D86.0 Sarcoidosis of lung
0.619 0.381 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.618 0.382 0.000
H53.4 Visual field defects
0.617 0.383 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.617 0.383 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.617 0.383 0.000
B33 Other viral diseases, not elsewhere classified
0.617 0.383 0.000
B30 Viral conjunctivitis
0.617 0.383 0.000
B27 Infectious mononucleosis
0.617 0.383 0.000
B26 Mumps
0.617 0.383 0.000
B25 Cytomegaloviral disease
0.617 0.383 0.000
N25-N29 Other disorders of kidney and ureter
0.617 0.383 0.000
H50.9 Strabismus, unspecified
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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