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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7750000
log Bayes Factor = 14.2462
Chromosome 6   position 33,103,321  (GRCh37) Explore rs7750000 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E03 Other hypothyroidism
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.005 0.995
E03.9 Hypothyroidism, unspecified
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.037 0.963
E04 Other non-toxic goitre
0.000 0.045 0.955
E06 Thyroiditis
0.000 0.048 0.952
E16 Other disorders of pancreatic internal secretion
0.000 0.061 0.939
E16.2 Hypoglycaemia, unspecified
0.000 0.073 0.927
E10.2 With renal complications
0.000 0.073 0.927
E10.4 With neurological complications
0.000 0.080 0.920
E10.5 With peripheral circulatory complications
0.000 0.080 0.920
E06.3 Autoimmune thyroiditis
0.000 0.093 0.907
E04.1 Non-toxic single thyroid nodule
0.000 0.101 0.899
E11 Non-insulin-dependent diabetes mellitus
0.000 0.133 0.867
E04.2 Non-toxic multinodular goitre
0.000 0.137 0.863
E50-E64 Other nutritional deficiencies
0.000 0.146 0.854
E10.6 With other specified complications
0.000 0.189 0.811
E11.4 With neurological complications
0.000 0.195 0.805
E11.3 With ophthalmic complications
0.000 0.203 0.797
E53 Deficiency of other B group vitamins
0.000 0.216 0.784
E10.0 With coma
0.000 0.235 0.765
E06.9 Thyroiditis, unspecified
0.000 0.243 0.757
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.244 0.756
E11.1 With ketoacidosis
0.000 0.249 0.751
E53.8 Deficiency of other specified B group vitamins
0.000 0.250 0.750
E10.8 With unspecified complications
0.000 0.258 0.742
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.275 0.725
E20-E35 Disorders of other endocrine glands
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.286 0.714
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.714
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.286 0.714
E27 Other disorders of adrenal gland
0.000 0.297 0.703
E04.0 Non-toxic diffuse goitre
0.000 0.301 0.699
E27.1 Primary adrenocortical insufficiency
0.000 0.307 0.693
E15 Nondiabetic hypoglycaemic coma
0.000 0.309 0.691
E04.8 Other specified non-toxic goitre
0.000 0.315 0.685
E06.5 Other chronic thyroiditis
0.000 0.317 0.682
E06.4 Drug-induced thyroiditis
0.000 0.317 0.682
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.317 0.682
E06.1 Subacute thyroiditis
0.000 0.317 0.682
E06.0 Acute thyroiditis
0.000 0.317 0.682
E11.2 With renal complications
0.000 0.322 0.678
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.326 0.673
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.326 0.673
E16.4 Abnormal secretion of gastrin
0.000 0.326 0.673
E16.3 Increased secretion of glucagon
0.000 0.326 0.673
E55 Vitamin D deficiency
0.000 0.336 0.664
E20 Hypoparathyroidism
0.000 0.344 0.656
E14 Unspecified diabetes mellitus
0.000 0.358 0.642
E11.6 With other specified complications
0.000 0.364 0.636
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.365 0.635
E16.1 Other hypoglycaemia
0.000 0.367 0.633
E11.0 With coma
0.000 0.371 0.629
E11.7 With multiple complications
0.000 0.378 0.622
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.383 0.617
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.387 0.612
E63 Other nutritional deficiencies
0.000 0.387 0.612
E56 Other vitamin deficiencies
0.000 0.387 0.612
E50 Vitamin A deficiency
0.000 0.387 0.612
E60 Dietary zinc deficiency
0.000 0.387 0.612
E59 Dietary selenium deficiency
0.000 0.387 0.612
E58 Dietary calcium deficiency
0.000 0.387 0.612
E54 Ascorbic acid deficiency
0.000 0.387 0.612
E52 Niacin deficiency [pellagra]
0.000 0.387 0.612
E20.9 Hypoparathyroidism, unspecified
0.000 0.393 0.607
E51 Thiamine deficiency
0.000 0.398 0.602
K90.0 Coeliac disease
0.000 0.411 0.589
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.429 0.571
E53.1 Pyridoxine deficiency
0.000 0.438 0.562
E53.0 Riboflavin deficiency
0.000 0.438 0.562
K91.4 Colostomy and enterostomy malfunction
0.000 0.441 0.559
E14.3 With ophthalmic complications
0.000 0.443 0.557
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.454 0.546
K90 Intestinal malabsorption
0.000 0.459 0.541
K90-K93 Other diseases of the digestive system
0.000 0.470 0.530
E27.2 Addisonian crisis
0.000 0.471 0.529
E55.9 Vitamin D deficiency, unspecified
0.000 0.472 0.528
E13 Other specified diabetes mellitus
0.000 0.472 0.527
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.480 0.520
E32 Diseases of thymus
0.000 0.480 0.520
E31 Polyglandular dysfunction
0.000 0.480 0.520
E30 Disorders of puberty, not elsewhere classified
0.000 0.480 0.520
E25 Adrenogenital disorders
0.000 0.480 0.520
E22 Hyperfunction of pituitary gland
0.000 0.480 0.520
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E04.9 Non-toxic goitre, unspecified
0.000 0.490 0.510
E40-E46 Malnutrition
0.001 0.491 0.508
E27.5 Adrenomedullary hyperfunction
0.000 0.496 0.504
E27.0 Other adrenocortical overactivity
0.000 0.496 0.504
E27.9 Disorder of adrenal gland, unspecified
0.000 0.497 0.503
E26 Hyperaldosteronism
0.000 0.503 0.497
E55.0 Rickets, active
0.000 0.524 0.476
E11.8 With unspecified complications
0.000 0.525 0.475
E20.8 Other hypoparathyroidism
0.000 0.529 0.470
E20.1 Pseudohypoparathyroidism
0.000 0.529 0.470
E20.0 Idiopathic hypoparathyroidism
0.000 0.529 0.470
E03.8 Other specified hypothyroidism
0.000 0.531 0.468
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.532 0.468
E14.1 With ketoacidosis
0.000 0.533 0.467
E14.7 With multiple complications
0.000 0.539 0.461
E14.6 With other specified complications
0.000 0.539 0.461
E14.2 Withrenal complications
0.000 0.539 0.461
E14.0 With coma
0.000 0.539 0.461
E28 Ovarian dysfunction
0.000 0.540 0.460
E14.8 With unspecified complications
0.000 0.544 0.456
E07 Other disorders of thyroid
0.000 0.544 0.456
E53.9 Vitamin B deficiency, unspecified
0.000 0.547 0.453
E14.5 With peripheral circulatory complications
0.000 0.554 0.446
E34 Other endocrine disorders
0.000 0.557 0.443
E50.9 Vitamin A deficiency, unspecified
0.000 0.561 0.439
E50.8 Other manifestations of vitamin A deficiency
0.000 0.561 0.439
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.561 0.439
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.561 0.439
E50.5 Vitamin A deficiency with night blindness
0.000 0.561 0.439
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.561 0.439
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.561 0.439
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.561 0.439
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.561 0.439
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.561 0.439
E56.9 Vitamin deficiency, unspecified
0.000 0.561 0.439
E56.8 Deficiency of other vitamins
0.000 0.561 0.439
E56.1 Deficiency of vitamin K
0.000 0.561 0.439
E56.0 Deficiency of vitamin E
0.000 0.561 0.439
E63.9 Nutritional deficiency, unspecified
0.000 0.561 0.439
E63.8 Other specified nutritional deficiencies
0.000 0.561 0.439
E63.1 Imbalance of constituents of food intake
0.000 0.561 0.439
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.561 0.439
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.561 0.439
E64.8 Sequelae of other nutritional deficiencies
0.000 0.561 0.439
E64.3 Sequelae of rickets
0.000 0.561 0.439
E64.2 Sequelae of vitamin C deficiency
0.000 0.561 0.439
E64.1 Sequelae of vitamin A deficiency
0.000 0.561 0.439
E64.0 Sequelae of protein-energy malnutrition
0.000 0.561 0.439
K91.3 Postoperative intestinal obstruction
0.000 0.561 0.439
E29 Testicular dysfunction
0.000 0.562 0.438
E51.9 Thiamine deficiency, unspecified
0.000 0.568 0.432
E51.8 Other manifestations of thiamine deficiency
0.000 0.568 0.432
E51.1 Beriberi
0.000 0.568 0.432
E61 Deficiency of other nutrient elements
0.000 0.574 0.425
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.578 0.422
E51.2 Wernicke's encephalopathy
0.000 0.579 0.421
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.585 0.415
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.585 0.415
E65-E68 Obesity and other hyperalimentation
0.000 0.590 0.410
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.595 0.405
K90.8 Other intestinal malabsorption
0.000 0.600 0.399
K91.1 Postgastric surgery syndromes
0.000 0.605 0.395
K91.5 Postcholecystectomy syndrome
0.000 0.608 0.391
K90.3 Pancreatic steatorrhoea
0.000 0.612 0.388
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.612 0.388
K90.1 Tropical sprue
0.000 0.612 0.388
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.620 0.380
E13.8 With unspecified complications
0.000 0.621 0.378
E13.7 With multiple complications
0.000 0.621 0.378
E13.6 With other specified complications
0.000 0.621 0.378
E13.5 With peripheral circulatory complications
0.000 0.621 0.378
E13.4 With neurological complications
0.000 0.621 0.378
E13.3 With ophthalmic complications
0.000 0.621 0.378
E13.2 With renal complications
0.000 0.621 0.378
E13.1 With ketoacidosis
0.000 0.621 0.378
E13.0 With coma
0.000 0.621 0.378
E14.4 With neurological complications
0.000 0.622 0.377
E26.0 Primary hyperaldosteronism
0.000 0.625 0.374
E25.9 Adrenogenital disorder, unspecified
0.000 0.627 0.373
E25.8 Other adrenogenital disorders
0.000 0.627 0.373
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.627 0.373
E30.9 Disorder of puberty, unspecified
0.000 0.627 0.373
E30.8 Other disorders of puberty
0.000 0.627 0.373
E30.1 Precocious puberty
0.000 0.627 0.373
E30.0 Delayed puberty
0.000 0.627 0.373
E31.9 Polyglandular dysfunction, unspecified
0.000 0.627 0.373
E31.8 Other polyglandular dysfunction
0.000 0.627 0.373
E31.1 Polyglandular hyperfunction
0.000 0.627 0.373
E31.0 Autoimmune polyglandular failure
0.000 0.627 0.373
E32.9 Disease of thymus, unspecified
0.000 0.627 0.373
E32.8 Other diseases of thymus
0.000 0.627 0.373
E32.1 Abscess of thymus
0.000 0.627 0.373
E32.0 Persistent hyperplasia of thymus
0.000 0.627 0.373
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.627 0.373
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.627 0.373
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.627 0.373
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.627 0.373
E22.8 Other hyperfunction of pituitary gland
0.000 0.627 0.373
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.635 0.364
E45 Retarded development following protein-energy malnutrition
0.001 0.635 0.364
E43 Unspecified severe protein-energy malnutrition
0.001 0.635 0.364
E42 Marasmic kwashiorkor
0.001 0.635 0.364
E41 Nutritional marasmus
0.001 0.635 0.364
E40 Kwashiorkor
0.001 0.635 0.364
E28.3 Primary ovarian failure
0.000 0.635 0.365
E24 Cushing's syndrome
0.000 0.641 0.359
E26.8 Other hyperaldosteronism
0.000 0.644 0.356
E26.1 Secondary hyperaldosteronism
0.000 0.644 0.356
E27.8 Other specified disorders of adrenal gland
0.000 0.645 0.355
K90.9 Intestinal malabsorption, unspecified
0.000 0.646 0.354
E22.1 Hyperprolactinaemia
0.000 0.647 0.353
E22.0 Acromegaly and pituitary gigantism
0.000 0.663 0.337
E28.9 Ovarian dysfunction, unspecified
0.000 0.670 0.330
E28.8 Other ovarian dysfunction
0.000 0.670 0.330
E28.1 Androgen excess
0.000 0.670 0.330
E28.0 Oestrogen excess
0.000 0.670 0.330
E07.1 Dyshormogenetic goitre
0.000 0.673 0.327
E07.0 Hypersecretion of calcitonin
0.000 0.673 0.327
E34.5 Androgen resistance syndrome
0.000 0.682 0.318
E34.4 Constitutional tall stature
0.000 0.682 0.318
E34.3 Short stature, not elsewhere classified
0.000 0.682 0.318
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.682 0.318
E34.1 Other hypersecretion of intestinal hormones
0.000 0.682 0.318
E29.9 Testicular dysfunction, unspecified
0.000 0.686 0.314
E29.8 Other testicular dysfunction
0.000 0.686 0.314
E29.0 Testicular hyperfunction
0.000 0.686 0.314
E34.9 Endocrine disorder, unspecified
0.000 0.688 0.312
E26.9 Hyperaldosteronism, unspecified
0.000 0.691 0.308
E23 Hypofunction and other disorders of pituitary gland
0.000 0.692 0.308
E61.9 Deficiency of nutrient element, unspecified
0.000 0.695 0.305
E61.8 Deficiency of other specified nutrient elements
0.000 0.695 0.305
E61.7 Deficiency of multiple nutrient elements
0.000 0.695 0.305
E61.6 Vanadium deficiency
0.000 0.695 0.305
E61.5 Molybdenum deficiency
0.000 0.695 0.305
E61.4 Chromium deficiency
0.000 0.695 0.305
E61.3 Manganese deficiency
0.000 0.695 0.305
E61.0 Copper deficiency
0.000 0.695 0.305
E67 Other hyperalimentation
0.000 0.706 0.294
E68 Sequelae of hyperalimentation
0.000 0.706 0.294
E07.8 Other specified disorders of thyroid
0.000 0.706 0.294
E14.9 Without complications
0.000 0.707 0.293
E34.0 Carcinoid syndrome
0.000 0.711 0.289
E34.8 Other specified endocrine disorders
0.000 0.714 0.285
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.727 0.272
K93.1 Megacolon in Chagas' disease
0.000 0.727 0.272
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.727 0.272
E44.1 Mild protein-energy malnutrition
0.001 0.738 0.261
E44.0 Moderate protein-energy malnutrition
0.001 0.738 0.261
E61.2 Magnesium deficiency
0.000 0.738 0.261
E24.2 Drug-induced Cushing's syndrome
0.000 0.741 0.259
E24.8 Other Cushing's syndrome
0.000 0.742 0.257
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.742 0.257
E24.3 Ectopic ACTH syndrome
0.000 0.742 0.257
E24.1 Nelson's syndrome
0.000 0.742 0.257
E65 Localised adiposity
0.000 0.746 0.254
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.749 0.251
E23.6 Other disorders of pituitary gland
0.000 0.763 0.237
E29.1 Testicular hypofunction
0.000 0.768 0.232
E23.7 Disorder of pituitary gland, unspecified
0.000 0.778 0.222
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.779 0.221
E23.1 Drug-induced hypopituitarism
0.000 0.779 0.221
E67.8 Other specified hyperalimentation
0.000 0.789 0.211
E67.3 Hypervitaminosis D
0.000 0.789 0.211
E67.2 Megavitamin-B6 syndrome
0.000 0.789 0.211
E67.1 Hypercarotenaemia
0.000 0.789 0.211
E67.0 Hypervitaminosis A
0.000 0.789 0.211
E24.9 Cushing's syndrome, unspecified
0.000 0.796 0.204
E28.2 Polycystic ovarian syndrome
0.000 0.799 0.201
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.799 0.201
E61.1 Iron deficiency
0.000 0.800 0.200
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.809 0.191
E13.9 Without complications
0.001 0.809 0.190
E24.0 Pituitary-dependent Cushing's disease
0.001 0.814 0.185
E05.5 Thyroid crisis or storm
0.000 0.820 0.180
E05.4 Thyrotoxicosis factitia
0.000 0.820 0.180
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.820 0.180
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.820 0.180
E11.5 With peripheral circulatory complications
0.001 0.827 0.172
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.830 0.169
E05.8 Other thyrotoxicosis
0.000 0.831 0.169
E46 Unspecified protein-energy malnutrition
0.001 0.841 0.158
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.842 0.157
E23.0 Hypopituitarism
0.000 0.852 0.148
E07.9 Disorder of thyroid, unspecified
0.000 0.853 0.147
E21.4 Other specified disorders of parathyroid gland
0.000 0.855 0.144
E21.2 Other hyperparathyroidism
0.000 0.855 0.144
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.860 0.139
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.874 0.126
E21.0 Primary hyperparathyroidism
0.000 0.879 0.121
M06.9 Rheumatoid arthritis, unspecified
0.000 0.880 0.120
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.887 0.113
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.892 0.108
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.893 0.107
E23.2 Diabetes insipidus
0.001 0.895 0.104
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.900 0.100
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.902 0.098
E66 Obesity
0.000 0.902 0.098
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.905 0.095
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.905 0.095
M35.0 Sicca syndrome [Sjogren]
0.000 0.916 0.084
M35 Other systemic involvement of connective tissue
0.000 0.919 0.081
M35.3 Polymyalgia rheumatica
0.000 0.920 0.080
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.920 0.080
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.921 0.078
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.924 0.076
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.925 0.075
E05.9 Thyrotoxicosis, unspecified
0.000 0.925 0.075
M35.1 Other overlap syndromes
0.000 0.928 0.072
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.928 0.072
E66.1 Drug-induced obesity
0.000 0.930 0.070
E21.3 Hyperparathyroidism, unspecified
0.000 0.930 0.069
E66.0 Obesity due to excess calories
0.000 0.939 0.061
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.942 0.058
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.942 0.058
M35.5 Multifocal fibrosclerosis
0.000 0.942 0.058
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.942 0.058
M35.2 Behcet's disease
0.000 0.942 0.058
M35.7 Hypermobility syndrome
0.000 0.943 0.057
H36.0 Diabetic retinopathy
0.000 0.943 0.057
K92 Other diseases of digestive system
0.000 0.944 0.056
M35.8 Other specified systemic involvement of connective tissue
0.000 0.944 0.055
E66.8 Other obesity
0.000 0.953 0.047
M06 Other rheumatoid arthritis
0.000 0.955 0.045
K92.9 Disease of digestive system, unspecified
0.000 0.956 0.044
K92.8 Other specified diseases of digestive system
0.000 0.958 0.042
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.958 0.042
M06.3 Rheumatoid nodule
0.000 0.965 0.035
M06.4 Inflammatory polyarthropathy
0.000 0.967 0.033
M06.8 Other specified rheumatoid arthritis
0.000 0.968 0.032
M06.2 Rheumatoid bursitis
0.000 0.968 0.032
M06.1 Adult-onset Still's disease
0.000 0.968 0.032
E70-E90 Metabolic disorders
0.000 0.971 0.029
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.973 0.027
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.973 0.026
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.974 0.026
H36 Retinal disorders in diseases classified elsewhere
0.000 0.974 0.026
M06.34 Rheumatoid nodule (Hand)
0.000 0.974 0.025
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.975 0.025
M06.38 Rheumatoid nodule (Other)
0.000 0.975 0.025
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.975 0.025
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.975 0.025
M06.33 Rheumatoid nodule (Forearm)
0.000 0.975 0.025
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.975 0.025
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.975 0.025
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.976 0.024
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.976 0.024
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.976 0.024
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.976 0.024
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.976 0.024
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.976 0.024
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.976 0.024
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.976 0.024
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.976 0.023
M06.18 Adult-onset Still's disease (Other)
0.000 0.976 0.023
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.976 0.023
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.976 0.023
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.976 0.023
M06.14 Adult-onset Still's disease (Hand)
0.000 0.976 0.023
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.976 0.023
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.976 0.023
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.976 0.023
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.976 0.023
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.976 0.023
M06.28 Rheumatoid bursitis (Other)
0.000 0.976 0.023
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.976 0.023
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.976 0.023
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.976 0.023
M06.24 Rheumatoid bursitis (Hand)
0.000 0.976 0.023
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.976 0.023
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.976 0.023
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.976 0.023
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.976 0.023
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.976 0.023
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.976 0.023
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.976 0.023
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.976 0.023
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.976 0.023
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.976 0.023
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.976 0.023
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.976 0.023
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.976 0.023
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.976 0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.977 0.023
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.978 0.022
E79 Disorders of purine and pyrimidine metabolism
0.000 0.978 0.021
E77 Disorders of glycoprotein metabolism
0.000 0.979 0.021
E76 Disorders of glycosaminoglycan metabolism
0.000 0.979 0.021
E72 Other disorders of amino-acid metabolism
0.000 0.979 0.021
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.979 0.021
E70 Disorders of aromatic amino-acid metabolism
0.000 0.979 0.021
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.979 0.021
E83 Disorders of mineral metabolism
0.000 0.979 0.021
E74 Other disorders of carbohydrate metabolism
0.000 0.980 0.020
E84 Cystic fibrosis
0.000 0.980 0.020
E89.0 Postprocedural hypothyroidism
0.000 0.980 0.020
M06.0 Seronegative rheumatoid arthritis
0.000 0.980 0.020
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.980 0.020
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.981 0.019
E83.1 Disorders of iron metabolism
0.000 0.981 0.019
E89.3 Postprocedural hypopituitarism
0.000 0.982 0.018
E89.2 Postprocedural hypoparathyroidism
0.000 0.982 0.018
E73 Lactose intolerance
0.000 0.982 0.018
E83.4 Disorders of magnesium metabolism
0.000 0.983 0.017
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.983 0.017
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.983 0.017
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.983 0.017
E89.5 Postprocedural testicular hypofunction
0.000 0.983 0.017
E89.1 Postprocedural hypoinsulinaemia
0.000 0.983 0.017
E85 Amyloidosis
0.000 0.983 0.016
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.984 0.016
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.984 0.015
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.984 0.015
E79.1 Lesch-Nyhan syndrome
0.000 0.984 0.015
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.985 0.015
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.985 0.015
E70.3 Albinism
0.000 0.985 0.015
E70.2 Disorders of tyrosine metabolism
0.000 0.985 0.015
E70.1 Other hyperphenylalaninaemias
0.000 0.985 0.015
E70.0 Classical phenylketonuria
0.000 0.985 0.015
E71.3 Disorders of fatty-acid metabolism
0.000 0.985 0.015
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.985 0.015
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.985 0.015
E71.0 Maple-syrup-urine disease
0.000 0.985 0.015
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.985 0.015
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.985 0.015
E72.5 Disorders of glycine metabolism
0.000 0.985 0.015
E72.4 Disorders of ornithine metabolism
0.000 0.985 0.015
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.985 0.015
E72.2 Disorders of urea cycle metabolism
0.000 0.985 0.015
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.985 0.015
E72.0 Disorders of amino-acid transport
0.000 0.985 0.015
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.985 0.015
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.985 0.015
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.985 0.015
E76.2 Other mucopolysaccharidoses
0.000 0.985 0.015
E76.1 Mucopolysaccharidosis, type II
0.000 0.985 0.015
E76.0 Mucopolysaccharidosis, type I
0.000 0.985 0.015
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.985 0.015
E77.8 Other disorders of glycoprotein metabolism
0.000 0.985 0.015
E77.1 Defects in glycoprotein degradation
0.000 0.985 0.015
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.985 0.015
E11.9 Without complications
0.000 0.985 0.015
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.985 0.015
E83.8 Other disorders of mineral metabolism
0.000 0.985 0.015
E83.2 Disorders of zinc metabolism
0.000 0.985 0.015
E83.0 Disorders of copper metabolism
0.000 0.985 0.015
E89.4 Postprocedural ovarian failure
0.000 0.985 0.015
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.985 0.015
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.985 0.015
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.985 0.015
E74.2 Disorders of galactose metabolism
0.000 0.985 0.015
E74.1 Disorders of fructose metabolism
0.000 0.985 0.015
E74.0 Glycogen storage disease
0.000 0.985 0.015
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.985 0.015
E84.8 Cystic fibrosis with other manifestations
0.000 0.985 0.015
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.985 0.015
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.985 0.015
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.985 0.014
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.985 0.014
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.985 0.014
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.985 0.014
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.985 0.014
E75.6 Lipid storage disorder, unspecified
0.000 0.985 0.014
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.985 0.014
E75.3 Sphingolipidosis, unspecified
0.000 0.985 0.014
E75.2 Other sphingolipidosis
0.000 0.985 0.014
E75.1 Other gangliosidosis
0.000 0.985 0.014
E75.0 GM2 gangliosidosis
0.000 0.985 0.014
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.986 0.014
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.986 0.014
E84.9 Cystic fibrosis, unspecified
0.000 0.986 0.014
E88 Other metabolic disorders
0.000 0.986 0.013
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.986 0.013
E75.5 Other lipid storage disorders
0.000 0.987 0.013
E73.8 Other lactose intolerance
0.000 0.987 0.013
E73.1 Secondary lactase deficiency
0.000 0.987 0.013
E73.0 Congenital lactase deficiency
0.000 0.987 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.987 0.013
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.987 0.013
E83.3 Disorders of phosphorus metabolism
0.000 0.987 0.013
Z87.8 Personal history of other specified conditions
0.000 0.987 0.013
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.987 0.012
E80.5 Crigler-Najjar syndrome
0.000 0.987 0.012
E80.3 Defects of catalase and peroxydase
0.000 0.987 0.012
E80.2 Other porphyria
0.000 0.987 0.012
E80.0 Hereditary erythropoietic porphyria
0.000 0.987 0.012
E86 Volume depletion
0.000 0.987 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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