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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7750795
log Bayes Factor = 20.1405
Chromosome 6   position 27,440,004  (GRCh37) Explore rs7750795 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.553 0.447
E10.9 Without complications
0.000 0.560 0.440
E10.6 With other specified complications
0.000 0.595 0.404
E10.5 With peripheral circulatory complications
0.000 0.598 0.402
E10.4 With neurological complications
0.000 0.604 0.396
E10.3 With ophthalmic complications
0.000 0.610 0.390
E10.1 With ketoacidosis
0.000 0.623 0.377
E10.8 With unspecified complications
0.000 0.638 0.362
E10.2 With renal complications
0.000 0.667 0.333
E10.0 With coma
0.000 0.679 0.321
E10.7 With multiple complications
0.000 0.679 0.320
E10-E14 Diabetes mellitus
0.000 0.715 0.285
K90 Intestinal malabsorption
0.000 0.764 0.236
E13 Other specified diabetes mellitus
0.000 0.765 0.235
E83 Disorders of mineral metabolism
0.000 0.771 0.229
E12 Malnutrition-related diabetes mellitus
0.000 0.795 0.205
E13.9 Without complications
0.000 0.799 0.201
E11 Non-insulin-dependent diabetes mellitus
0.000 0.811 0.189
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.814 0.186
E70-E90 Metabolic disorders
0.000 0.815 0.185
E88 Other metabolic disorders
0.000 0.822 0.178
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.826 0.174
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.828 0.172
K90.3 Pancreatic steatorrhoea
0.000 0.830 0.170
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.830 0.170
K90.1 Tropical sprue
0.000 0.830 0.170
E13.8 With unspecified complications
0.000 0.831 0.168
E13.7 With multiple complications
0.000 0.831 0.168
E13.6 With other specified complications
0.000 0.831 0.168
E13.5 With peripheral circulatory complications
0.000 0.831 0.168
E13.4 With neurological complications
0.000 0.831 0.168
E13.2 With renal complications
0.000 0.831 0.168
E13.1 With ketoacidosis
0.000 0.831 0.168
E13.0 With coma
0.000 0.831 0.168
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.834 0.166
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.836 0.164
E83.8 Other disorders of mineral metabolism
0.000 0.836 0.164
E83.2 Disorders of zinc metabolism
0.000 0.836 0.164
E83.0 Disorders of copper metabolism
0.000 0.836 0.164
E13.3 With ophthalmic complications
0.000 0.837 0.163
E16 Other disorders of pancreatic internal secretion
0.000 0.838 0.162
K90.8 Other intestinal malabsorption
0.000 0.838 0.161
E11.2 With renal complications
0.000 0.840 0.160
E14 Unspecified diabetes mellitus
0.000 0.841 0.159
E11.0 With coma
0.000 0.843 0.157
E16.2 Hypoglycaemia, unspecified
0.000 0.844 0.156
E11.4 With neurological complications
0.000 0.847 0.153
E40-E46 Malnutrition
0.000 0.851 0.149
E14.3 With ophthalmic complications
0.000 0.853 0.147
E12.9 Without complications
0.000 0.853 0.147
E12.8 With unspecified complications
0.000 0.853 0.147
E12.7 With multiple complications
0.000 0.853 0.147
E12.6 With other specified complications
0.000 0.853 0.147
E12.5 With peripheral circulatory complications
0.000 0.853 0.147
E12.4 With neurological complications
0.000 0.853 0.147
E12.3 With ophthalmic complications
0.000 0.853 0.147
E12.2 With renal complications
0.000 0.853 0.147
E12.1 With ketoacidosis
0.000 0.853 0.147
E12.0 With coma
0.000 0.853 0.147
E11.1 With ketoacidosis
0.000 0.857 0.143
E85 Amyloidosis
0.000 0.857 0.143
E88.8 Other specified metabolic disorders
0.000 0.859 0.141
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.859 0.141
E11.8 With unspecified complications
0.000 0.860 0.140
E88.2 Lipomatosis, not elsewhere classified
0.000 0.860 0.139
E11.7 With multiple complications
0.000 0.864 0.136
E11.5 With peripheral circulatory complications
0.000 0.865 0.135
E88.3 Tumour lysis syndrome
0.000 0.866 0.134
E84 Cystic fibrosis
0.000 0.867 0.133
E77 Disorders of glycoprotein metabolism
0.000 0.867 0.133
E76 Disorders of glycosaminoglycan metabolism
0.000 0.867 0.133
E72 Other disorders of amino-acid metabolism
0.000 0.867 0.133
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.867 0.133
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.867 0.133
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.869 0.131
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.872 0.128
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.873 0.127
E11.6 With other specified complications
0.000 0.876 0.124
E70 Disorders of aromatic amino-acid metabolism
0.000 0.876 0.124
E15 Nondiabetic hypoglycaemic coma
0.000 0.876 0.123
E46 Unspecified protein-energy malnutrition
0.000 0.878 0.121
E14.5 With peripheral circulatory complications
0.000 0.880 0.120
E88.9 Metabolic disorder, unspecified
0.000 0.881 0.119
E79 Disorders of purine and pyrimidine metabolism
0.000 0.882 0.117
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.884 0.116
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.884 0.116
E16.4 Abnormal secretion of gastrin
0.000 0.884 0.116
E16.3 Increased secretion of glucagon
0.000 0.884 0.116
E85.9 Amyloidosis, unspecified
0.000 0.885 0.115
E14.7 With multiple complications
0.000 0.886 0.114
E14.2 Withrenal complications
0.000 0.886 0.114
E14.0 With coma
0.000 0.886 0.114
E83.3 Disorders of phosphorus metabolism
0.000 0.886 0.114
E14.6 With other specified complications
0.000 0.892 0.108
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.893 0.107
E45 Retarded development following protein-energy malnutrition
0.000 0.893 0.107
E43 Unspecified severe protein-energy malnutrition
0.000 0.893 0.107
E42 Marasmic kwashiorkor
0.000 0.893 0.107
E41 Nutritional marasmus
0.000 0.893 0.107
E40 Kwashiorkor
0.000 0.893 0.107
E14.4 With neurological complications
0.000 0.896 0.104
E85.4 Organ-limited amyloidosis
0.000 0.896 0.104
E14.1 With ketoacidosis
0.000 0.896 0.103
E85.8 Other amyloidosis
0.000 0.897 0.102
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.897 0.102
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.897 0.102
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.897 0.102
E65-E68 Obesity and other hyperalimentation
0.000 0.898 0.102
E73 Lactose intolerance
0.000 0.899 0.101
E11.3 With ophthalmic complications
0.000 0.902 0.098
E85.3 Secondary systemic amyloidosis
0.000 0.902 0.097
E74 Other disorders of carbohydrate metabolism
0.000 0.904 0.096
E71.3 Disorders of fatty-acid metabolism
0.000 0.905 0.095
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.905 0.095
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.905 0.095
E71.0 Maple-syrup-urine disease
0.000 0.905 0.095
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.905 0.095
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.905 0.095
E72.5 Disorders of glycine metabolism
0.000 0.905 0.095
E72.4 Disorders of ornithine metabolism
0.000 0.905 0.095
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.905 0.095
E72.2 Disorders of urea cycle metabolism
0.000 0.905 0.095
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.905 0.095
E72.0 Disorders of amino-acid transport
0.000 0.905 0.095
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.905 0.095
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.905 0.095
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.905 0.095
E76.2 Other mucopolysaccharidoses
0.000 0.905 0.095
E76.1 Mucopolysaccharidosis, type II
0.000 0.905 0.095
E76.0 Mucopolysaccharidosis, type I
0.000 0.905 0.095
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.905 0.095
E77.8 Other disorders of glycoprotein metabolism
0.000 0.905 0.095
E77.1 Defects in glycoprotein degradation
0.000 0.905 0.095
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.905 0.095
E84.9 Cystic fibrosis, unspecified
0.000 0.905 0.095
E84.8 Cystic fibrosis with other manifestations
0.000 0.905 0.095
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.905 0.095
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.905 0.095
E80.4 Gilbert's syndrome
0.000 0.905 0.095
E75.6 Lipid storage disorder, unspecified
0.000 0.908 0.092
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.908 0.092
E75.3 Sphingolipidosis, unspecified
0.000 0.908 0.092
E75.2 Other sphingolipidosis
0.000 0.908 0.092
E75.1 Other gangliosidosis
0.000 0.908 0.092
E75.0 GM2 gangliosidosis
0.000 0.908 0.092
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.908 0.091
E80.5 Crigler-Najjar syndrome
0.000 0.908 0.091
E80.3 Defects of catalase and peroxydase
0.000 0.908 0.091
E80.1 Porphyria cutanea tarda
0.000 0.908 0.091
E80.0 Hereditary erythropoietic porphyria
0.000 0.908 0.091
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.909 0.091
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.911 0.089
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.911 0.089
E70.2 Disorders of tyrosine metabolism
0.000 0.911 0.089
E70.1 Other hyperphenylalaninaemias
0.000 0.911 0.089
E70.0 Classical phenylketonuria
0.000 0.911 0.089
E80.6 Other disorders of bilirubin metabolism
0.000 0.911 0.089
E75.5 Other lipid storage disorders
0.000 0.913 0.087
E80.2 Other porphyria
0.000 0.915 0.085
E16.1 Other hypoglycaemia
0.000 0.915 0.084
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.915 0.084
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.915 0.084
E79.1 Lesch-Nyhan syndrome
0.000 0.915 0.084
E14.8 With unspecified complications
0.000 0.918 0.082
E65 Localised adiposity
0.000 0.919 0.081
E70.3 Albinism
0.000 0.920 0.080
K90.9 Intestinal malabsorption, unspecified
0.000 0.922 0.077
E44.1 Mild protein-energy malnutrition
0.000 0.923 0.077
E44.0 Moderate protein-energy malnutrition
0.000 0.923 0.077
E83.4 Disorders of magnesium metabolism
0.000 0.924 0.076
E67 Other hyperalimentation
0.000 0.927 0.073
E68 Sequelae of hyperalimentation
0.000 0.927 0.073
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.927 0.073
E73.8 Other lactose intolerance
0.000 0.927 0.072
E73.1 Secondary lactase deficiency
0.000 0.927 0.072
E73.0 Congenital lactase deficiency
0.000 0.927 0.072
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.929 0.071
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.930 0.070
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.930 0.069
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.931 0.069
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.931 0.069
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.931 0.069
E74.2 Disorders of galactose metabolism
0.000 0.931 0.069
E74.1 Disorders of fructose metabolism
0.000 0.931 0.069
E89.4 Postprocedural ovarian failure
0.000 0.931 0.069
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.932 0.068
E50-E64 Other nutritional deficiencies
0.000 0.933 0.067
E89.2 Postprocedural hypoparathyroidism
0.000 0.933 0.066
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.934 0.066
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.934 0.066
E89.5 Postprocedural testicular hypofunction
0.000 0.934 0.066
E89.1 Postprocedural hypoinsulinaemia
0.000 0.934 0.066
E74.0 Glycogen storage disease
0.000 0.938 0.062
E87.0 Hyperosmolality and hypernatraemia
0.000 0.940 0.060
E87.5 Hyperkalaemia
0.000 0.940 0.060
E87.3 Alkalosis
0.000 0.943 0.057
E78.2 Mixed hyperlipidaemia
0.000 0.945 0.055
E78.4 Other hyperlipidaemia
0.000 0.946 0.054
E67.8 Other specified hyperalimentation
0.000 0.947 0.053
E67.3 Hypervitaminosis D
0.000 0.947 0.053
E67.2 Megavitamin-B6 syndrome
0.000 0.947 0.053
E67.1 Hypercarotenaemia
0.000 0.947 0.053
E67.0 Hypervitaminosis A
0.000 0.947 0.053
E89.0 Postprocedural hypothyroidism
0.000 0.947 0.053
E78.3 Hyperchylomicronaemia
0.000 0.948 0.052
E87.7 Fluid overload
0.000 0.949 0.051
E78.1 Pure hyperglyceridaemia
0.000 0.949 0.051
E87.4 Mixed disorder of acid-base balance
0.000 0.950 0.050
E78.6 Lipoprotein deficiency
0.000 0.950 0.050
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.952 0.048
E63 Other nutritional deficiencies
0.000 0.952 0.048
E50 Vitamin A deficiency
0.000 0.952 0.048
E60 Dietary zinc deficiency
0.000 0.952 0.048
E59 Dietary selenium deficiency
0.000 0.952 0.048
E54 Ascorbic acid deficiency
0.000 0.952 0.048
E52 Niacin deficiency [pellagra]
0.000 0.952 0.048
E00-E07 Disorders of thyroid gland
0.000 0.952 0.048
E58 Dietary calcium deficiency
0.000 0.952 0.048
E56 Other vitamin deficiencies
0.000 0.953 0.046
E53 Deficiency of other B group vitamins
0.000 0.954 0.046
E51 Thiamine deficiency
0.000 0.954 0.046
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.954 0.045
E20-E35 Disorders of other endocrine glands
0.000 0.957 0.043
E73.9 Lactose intolerance, unspecified
0.001 0.959 0.041
E55 Vitamin D deficiency
0.000 0.959 0.040
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.961 0.039
E83.5 Disorders of calcium metabolism
0.000 0.963 0.037
R31 Unspecified haematuria
0.037 0.963 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.964 0.036
E07 Other disorders of thyroid
0.000 0.965 0.035
E50.9 Vitamin A deficiency, unspecified
0.000 0.965 0.035
E50.8 Other manifestations of vitamin A deficiency
0.000 0.965 0.035
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.965 0.035
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.965 0.035
E50.5 Vitamin A deficiency with night blindness
0.000 0.965 0.035
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.965 0.035
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.965 0.035
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.965 0.035
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.965 0.035
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.965 0.035
E63.9 Nutritional deficiency, unspecified
0.000 0.965 0.035
E63.8 Other specified nutritional deficiencies
0.000 0.965 0.035
E63.1 Imbalance of constituents of food intake
0.000 0.965 0.035
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.965 0.035
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.965 0.035
E64.8 Sequelae of other nutritional deficiencies
0.000 0.965 0.035
E64.3 Sequelae of rickets
0.000 0.965 0.035
E64.2 Sequelae of vitamin C deficiency
0.000 0.965 0.035
E64.1 Sequelae of vitamin A deficiency
0.000 0.965 0.035
E64.0 Sequelae of protein-energy malnutrition
0.000 0.965 0.035
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.965 0.035
E00 Congenital iodine-deficiency syndrome
0.000 0.965 0.035
E87.2 Acidosis
0.000 0.965 0.035
E89.3 Postprocedural hypopituitarism
0.000 0.966 0.034
E20 Hypoparathyroidism
0.000 0.966 0.034
E56.9 Vitamin deficiency, unspecified
0.000 0.966 0.033
E56.8 Deficiency of other vitamins
0.000 0.966 0.033
E56.0 Deficiency of vitamin E
0.000 0.966 0.033
E53.1 Pyridoxine deficiency
0.000 0.967 0.033
E53.0 Riboflavin deficiency
0.000 0.967 0.033
E51.9 Thiamine deficiency, unspecified
0.000 0.967 0.033
E51.8 Other manifestations of thiamine deficiency
0.000 0.967 0.033
E51.1 Beriberi
0.000 0.967 0.033
E27.1 Primary adrenocortical insufficiency
0.000 0.967 0.033
E26 Hyperaldosteronism
0.000 0.967 0.033
E06 Thyroiditis
0.000 0.968 0.032
E27 Other disorders of adrenal gland
0.000 0.968 0.032
E56.1 Deficiency of vitamin K
0.000 0.968 0.032
E29 Testicular dysfunction
0.000 0.968 0.032
E24 Cushing's syndrome
0.000 0.969 0.031
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.969 0.031
E32 Diseases of thymus
0.000 0.969 0.031
E31 Polyglandular dysfunction
0.000 0.969 0.031
E30 Disorders of puberty, not elsewhere classified
0.000 0.969 0.031
E25 Adrenogenital disorders
0.000 0.969 0.031
E14.9 Without complications
0.000 0.969 0.031
E51.2 Wernicke's encephalopathy
0.000 0.969 0.031
E04 Other non-toxic goitre
0.000 0.970 0.030
E55.0 Rickets, active
0.000 0.971 0.029
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.971 0.028
E34 Other endocrine disorders
0.000 0.972 0.028
E53.8 Deficiency of other specified B group vitamins
0.000 0.972 0.028
E20.9 Hypoparathyroidism, unspecified
0.000 0.973 0.027
E07.9 Disorder of thyroid, unspecified
0.000 0.973 0.027
E23 Hypofunction and other disorders of pituitary gland
0.000 0.973 0.027
E24.2 Drug-induced Cushing's syndrome
0.000 0.973 0.027
E07.1 Dyshormogenetic goitre
0.000 0.974 0.025
E07.0 Hypersecretion of calcitonin
0.000 0.974 0.025
E04.9 Non-toxic goitre, unspecified
0.000 0.974 0.026
E26.0 Primary hyperaldosteronism
0.000 0.975 0.025
E86 Volume depletion
0.000 0.975 0.025
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.975 0.025
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.975 0.025
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.975 0.025
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.975 0.025
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.975 0.025
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.975 0.025
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.975 0.025
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.975 0.025
E61 Deficiency of other nutrient elements
0.001 0.975 0.024
E20.8 Other hypoparathyroidism
0.000 0.975 0.024
E20.1 Pseudohypoparathyroidism
0.000 0.975 0.024
E20.0 Idiopathic hypoparathyroidism
0.000 0.975 0.024
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.975 0.024
E07.8 Other specified disorders of thyroid
0.000 0.976 0.024
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.976 0.024
E28 Ovarian dysfunction
0.000 0.976 0.024
E23.2 Diabetes insipidus
0.000 0.976 0.024
E26.9 Hyperaldosteronism, unspecified
0.000 0.976 0.024
E26.8 Other hyperaldosteronism
0.000 0.976 0.024
E26.1 Secondary hyperaldosteronism
0.000 0.976 0.024
E29.1 Testicular hypofunction
0.000 0.976 0.023
E78.8 Other disorders of lipoprotein metabolism
0.000 0.977 0.023
E06.5 Other chronic thyroiditis
0.000 0.977 0.023
E06.4 Drug-induced thyroiditis
0.000 0.977 0.023
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.977 0.023
E06.1 Subacute thyroiditis
0.000 0.977 0.023
E06.0 Acute thyroiditis
0.000 0.977 0.023
E27.5 Adrenomedullary hyperfunction
0.000 0.977 0.023
E27.0 Other adrenocortical overactivity
0.000 0.977 0.023
E29.9 Testicular dysfunction, unspecified
0.000 0.977 0.023
E29.8 Other testicular dysfunction
0.000 0.977 0.023
E29.0 Testicular hyperfunction
0.000 0.977 0.023
E04.0 Non-toxic diffuse goitre
0.000 0.977 0.023
E24.8 Other Cushing's syndrome
0.000 0.977 0.023
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.977 0.023
E24.3 Ectopic ACTH syndrome
0.000 0.977 0.023
E24.1 Nelson's syndrome
0.000 0.977 0.023
E06.3 Autoimmune thyroiditis
0.000 0.977 0.023
E25.9 Adrenogenital disorder, unspecified
0.000 0.977 0.022
E25.8 Other adrenogenital disorders
0.000 0.977 0.022
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.977 0.022
E30.9 Disorder of puberty, unspecified
0.000 0.977 0.022
E30.8 Other disorders of puberty
0.000 0.977 0.022
E30.1 Precocious puberty
0.000 0.977 0.022
E30.0 Delayed puberty
0.000 0.977 0.022
E31.9 Polyglandular dysfunction, unspecified
0.000 0.977 0.022
E31.8 Other polyglandular dysfunction
0.000 0.977 0.022
E31.1 Polyglandular hyperfunction
0.000 0.977 0.022
E31.0 Autoimmune polyglandular failure
0.000 0.977 0.022
E32.9 Disease of thymus, unspecified
0.000 0.977 0.022
E32.8 Other diseases of thymus
0.000 0.977 0.022
E32.1 Abscess of thymus
0.000 0.977 0.022
E32.0 Persistent hyperplasia of thymus
0.000 0.977 0.022
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.977 0.022
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.977 0.022
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.977 0.022
E24.0 Pituitary-dependent Cushing's disease
0.000 0.978 0.022
E04.8 Other specified non-toxic goitre
0.000 0.978 0.022
E06.9 Thyroiditis, unspecified
0.000 0.978 0.022
E03 Other hypothyroidism
0.000 0.978 0.022
E55.9 Vitamin D deficiency, unspecified
0.000 0.978 0.021
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.979 0.021
G31.8 Other specified degenerative diseases of nervous system
0.000 0.980 0.020
E34.5 Androgen resistance syndrome
0.000 0.980 0.020
E34.4 Constitutional tall stature
0.000 0.980 0.020
E34.3 Short stature, not elsewhere classified
0.000 0.980 0.020
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.980 0.020
E34.1 Other hypersecretion of intestinal hormones
0.000 0.980 0.020
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.980 0.020
E34.0 Carcinoid syndrome
0.000 0.980 0.020
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.980 0.019
E23.1 Drug-induced hypopituitarism
0.000 0.980 0.019
E27.2 Addisonian crisis
0.000 0.981 0.019
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.981 0.019
E05.8 Other thyrotoxicosis
0.000 0.981 0.019
E34.8 Other specified endocrine disorders
0.000 0.981 0.019
E34.9 Endocrine disorder, unspecified
0.000 0.981 0.019
E23.7 Disorder of pituitary gland, unspecified
0.000 0.981 0.019
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.982 0.018
E61.9 Deficiency of nutrient element, unspecified
0.001 0.982 0.017
E61.8 Deficiency of other specified nutrient elements
0.001 0.982 0.017
E61.7 Deficiency of multiple nutrient elements
0.001 0.982 0.017
E61.6 Vanadium deficiency
0.001 0.982 0.017
E61.5 Molybdenum deficiency
0.001 0.982 0.017
E61.4 Chromium deficiency
0.001 0.982 0.017
E61.3 Manganese deficiency
0.001 0.982 0.017
E61.0 Copper deficiency
0.001 0.982 0.017
E66 Obesity
0.000 0.982 0.018
G31.0 Circumscribed brain atrophy
0.000 0.982 0.018
G30 Alzheimer's disease
0.000 0.982 0.018
E24.9 Cushing's syndrome, unspecified
0.000 0.982 0.018
E05.5 Thyroid crisis or storm
0.000 0.982 0.018
E05.4 Thyrotoxicosis factitia
0.000 0.982 0.018
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.982 0.018
E28.9 Ovarian dysfunction, unspecified
0.000 0.982 0.017
E28.8 Other ovarian dysfunction
0.000 0.982 0.017
E28.1 Androgen excess
0.000 0.982 0.017
E28.0 Oestrogen excess
0.000 0.982 0.017
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.983 0.017
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.983 0.017
E28.2 Polycystic ovarian syndrome
0.000 0.983 0.017
E23.6 Other disorders of pituitary gland
0.000 0.983 0.017
G30-G32 Other degenerative diseases of the nervous system
0.000 0.983 0.017
G30.9 Alzheimer's disease, unspecified
0.000 0.983 0.017
E03.8 Other specified hypothyroidism
0.000 0.983 0.017
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.984 0.016
G30.0 Alzheimer's disease with early onset
0.000 0.984 0.016
K90-K93 Other diseases of the digestive system
0.000 0.984 0.016
E04.1 Non-toxic single thyroid nodule
0.000 0.984 0.016
E03.5 Myxoedema coma
0.000 0.984 0.016
E03.4 Atrophy of thyroid (acquired)
0.000 0.984 0.016
E03.3 Postinfectious hypothyroidism
0.000 0.984 0.016
E03.1 Congenital hypothyroidism without goitre
0.000 0.984 0.016
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.984 0.016
E27.8 Other specified disorders of adrenal gland
0.000 0.985 0.015
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.985 0.015
E04.2 Non-toxic multinodular goitre
0.000 0.985 0.015
M25.57 Pain in joint (Ankle and foot)
0.000 0.985 0.015
E22 Hyperfunction of pituitary gland
0.000 0.985 0.015
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.985 0.015
G30.8 Other Alzheimer's disease
0.000 0.986 0.014
E61.2 Magnesium deficiency
0.001 0.986 0.013
E87.6 Hypokalaemia
0.000 0.986 0.014
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.987 0.013
E66.1 Drug-induced obesity
0.000 0.987 0.013
G30.1 Alzheimer's disease with late onset
0.000 0.987 0.013
M25.5 Pain in joint
0.000 0.987 0.013
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.987 0.013
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.988 0.012
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.988 0.012
E27.9 Disorder of adrenal gland, unspecified
0.001 0.988 0.011
E66.0 Obesity due to excess calories
0.000 0.988 0.011
G31.2 Degeneration of nervous system due to alcohol
0.000 0.989 0.011
G44.2 Tension-type headache
0.011 0.989 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.989 0.011
E22.8 Other hyperfunction of pituitary gland
0.000 0.989 0.011
M25.58 Pain in joint (Other)
0.000 0.989 0.011
E28.3 Primary ovarian failure
0.001 0.989 0.010
M25.52 Pain in joint (Upper arm)
0.000 0.989 0.011
M25.51 Pain in joint (Shoulder region)
0.000 0.989 0.011
E22.1 Hyperprolactinaemia
0.000 0.990 0.010
E21.4 Other specified disorders of parathyroid gland
0.000 0.991 0.009
E21.2 Other hyperparathyroidism
0.000 0.991 0.009
E23.0 Hypopituitarism
0.000 0.991 0.009
M25.54 Pain in joint (Hand)
0.000 0.991 0.009
M25.53 Pain in joint (Forearm)
0.000 0.991 0.009
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.991 0.009
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.991 0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.991 0.009
K93.1 Megacolon in Chagas' disease
0.000 0.991 0.009
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.991 0.009
E11.9 Without complications
0.000 0.992 0.008
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.992 0.008
E21.3 Hyperparathyroidism, unspecified
0.000 0.992 0.008
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.993 0.007
K22.8 Other specified diseases of oesophagus
0.007 0.993 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.993 0.006
E21.0 Primary hyperparathyroidism
0.000 0.993 0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.993 0.006
M25.59 Pain in joint (Site unspecified)
0.000 0.994 0.006
E61.1 Iron deficiency
0.002 0.994 0.005
G44 Other headache syndromes
0.006 0.994 0.000
N60.1 Diffuse cystic mastopathy
0.000 0.994 0.006
K02.9 Dental caries, unspecified
0.000 0.994 0.006
K56.4 Other impaction of intestine
0.005 0.995 0.000
G44.8 Other specified headache syndromes
0.005 0.995 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.005 0.995 0.000
K02.8 Other dental caries
0.000 0.995 0.005
G44.0 Cluster headache syndrome
0.005 0.995 0.000
G44.1 Vascular headache, not elsewhere classified
0.004 0.995 0.000
K02 Dental caries
0.000 0.995 0.005
G44.4 Drug-induced headache, not elsewhere classified
0.004 0.995 0.000
G82.5 Tetraplegia, unspecified
0.000 0.995 0.005
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.004 0.996 0.000
G44.3 Chronic posttraumatic headache
0.004 0.996 0.000
G82.4 Spastic tetraplegia
0.000 0.996 0.004
M41.9 Scoliosis, unspecified
0.004 0.996 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
K56.2 Volvulus
0.004 0.996 0.000
G82 Paraplegia and tetraplegia
0.000 0.996 0.004
K56 Paralytic ileus and intestinal obstruction without hernia
0.004 0.996 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.996 0.004
K02.1 Caries of dentin
0.000 0.996 0.004
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
G82.1 Spastic paraplegia
0.000 0.996 0.004
Z34.9 Supervision of normal pregnancy, unspecified
0.004 0.996 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.004 0.996 0.000
G71.1 Myotonic disorders
0.000 0.996 0.004
M67.8 Other specified disorders of synovium and tendon
0.000 0.996 0.004
M25.50 Pain in joint (Multiple sites)
0.000 0.996 0.003
K02.5 Caries with pulp exposure
0.000 0.996 0.003
K02.4 Odontoclasia
0.000 0.996 0.003
K02.3 Arrested dental caries
0.000 0.996 0.003
K02.2 Caries of cementum
0.000 0.996 0.003
K02.0 Caries limited to enamel
0.000 0.996 0.003
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.003 0.996 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.004 0.996 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
C71.2 Temporal lobe
0.003 0.997 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.997 0.003
N04.9 Unspecified
0.000 0.997 0.003
M79.10 Myalgia (Multiple sites)
0.003 0.997 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.003 0.997 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.003 0.997 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.003 0.997 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.003 0.997 0.000
K56.3 Gallstone ileus
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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