TreeWAS – Variant ID: rs7754443

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.006	0.994
M45 Ankylosing spondylitis	0.000	0.034	0.966
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.057	0.943
L40.0 Psoriasis vulgaris	0.000	0.065	0.935
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.106	0.894
L40.8 Other psoriasis	0.000	0.202	0.798
L40.3 Pustulosis palmaris et plantaris	0.000	0.245	0.755
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
L40.1 Generalised pustular psoriasis	0.000	0.283	0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.307	0.693
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.307	0.693
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.307	0.693
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.307	0.693
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.307	0.693
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.307	0.693
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.307	0.693
E03 Other hypothyroidism	0.000	0.349	0.651
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.406	0.594
M07.3 Other psoriatic arthropathies	0.000	0.427	0.573
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.435	0.565
E03.8 Other specified hypothyroidism	0.000	0.440	0.560
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.445	0.555
E03.5 Myxoedema coma	0.000	0.533	0.467
E03.4 Atrophy of thyroid (acquired)	0.000	0.533	0.467
E03.3 Postinfectious hypothyroidism	0.000	0.533	0.467
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.557	0.443
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.576	0.424
M07.38 Other psoriatic arthropathies (Other)	0.000	0.589	0.411
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.589	0.411
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.589	0.411
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.589	0.411
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.589	0.411
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.589	0.411
E03.1 Congenital hypothyroidism without goitre	0.000	0.591	0.409
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.595	0.405
G35 Multiple sclerosis	0.000	0.701	0.299
K90 Intestinal malabsorption	0.000	0.741	0.259
M07 Psoriatic and enteropathic arthropathies	0.001	0.757	0.242
L40-L45 Papulosquamous disorders	0.000	0.784	0.216
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.787	0.213
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.789	0.211
G30-G32 Other degenerative diseases of the nervous system	0.000	0.795	0.205
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.798	0.202
G31.2 Degeneration of nervous system due to alcohol	0.000	0.811	0.189
G31.8 Other specified degenerative diseases of nervous system	0.000	0.812	0.188
Chapter VI Diseases of the nervous system	0.000	0.812	0.188
K90.3 Pancreatic steatorrhoea	0.000	0.814	0.186
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.814	0.186
K90.1 Tropical sprue	0.000	0.814	0.186
G30 Alzheimer's disease	0.000	0.815	0.185
K90.8 Other intestinal malabsorption	0.000	0.819	0.181
M07.6 Other enteropathic arthropathies	0.001	0.826	0.174
M07.5 Arthropathy in ulcerative colitis	0.001	0.826	0.174
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.001	0.826	0.174
M07.2 Psoriatic spondylitis	0.001	0.826	0.174
M07.1 Arthritis mutilans	0.001	0.826	0.174
M07.0 Distal interphalangeal psoriatic arthropathy	0.001	0.826	0.174
G31.0 Circumscribed brain atrophy	0.000	0.828	0.172
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.829	0.171
G30.9 Alzheimer's disease, unspecified	0.000	0.834	0.166
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.843	0.157
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.843	0.157
G62 Other polyneuropathies	0.000	0.845	0.155
L44 Other papulosquamous disorders	0.000	0.845	0.155
L41 Parapsoriasis	0.000	0.845	0.155
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.845	0.155
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.846	0.154
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.848	0.152
K90.9 Intestinal malabsorption, unspecified	0.000	0.848	0.152
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.849	0.151
L42 Pityriasis rosea	0.000	0.850	0.150
G70-G73 Diseases of myoneural junction and muscle	0.000	0.851	0.149
G62.9 Polyneuropathy, unspecified	0.000	0.852	0.148
G30.1 Alzheimer's disease with late onset	0.000	0.857	0.143
G36 Other acute disseminated demyelination	0.000	0.858	0.142
G83 Other paralytic syndromes	0.000	0.860	0.140
G30.0 Alzheimer's disease with early onset	0.000	0.862	0.138
G61 Inflammatory polyneuropathy	0.000	0.865	0.135
G83.4 Cauda equina syndrome	0.000	0.868	0.132
G60 Hereditary and idiopathic neuropathy	0.000	0.868	0.132
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.869	0.131
G30.8 Other Alzheimer's disease	0.000	0.870	0.130
G03 Meningitis due to other and unspecified causes	0.000	0.872	0.128
G00 Bacterial meningitis, not elsewhere classified	0.000	0.874	0.126
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.001	0.875	0.125
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.001	0.875	0.125
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.001	0.875	0.125
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.001	0.875	0.125
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.001	0.875	0.125
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.001	0.875	0.125
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.001	0.875	0.125
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.001	0.875	0.125
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.001	0.875	0.125
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.001	0.875	0.125
M07.19 Arthritis mutilans (Site unspecified)	0.001	0.875	0.125
M07.18 Arthritis mutilans (Other)	0.001	0.875	0.125
M07.17 Arthritis mutilans (Ankle and foot)	0.001	0.875	0.125
M07.16 Arthritis mutilans (Lower leg)	0.001	0.875	0.125
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.001	0.875	0.125
M07.14 Arthritis mutilans (Hand)	0.001	0.875	0.125
M07.13 Arthritis mutilans (Forearm)	0.001	0.875	0.125
M07.12 Arthritis mutilans (Upper arm)	0.001	0.875	0.125
M07.11 Arthritis mutilans (Shoulder region)	0.001	0.875	0.125
M07.10 Arthritis mutilans (Multiple sites)	0.001	0.875	0.125
M07.29 Psoriatic spondylitis (Site unspecified)	0.001	0.875	0.125
M07.28 Psoriatic spondylitis (Other)	0.001	0.875	0.125
M07.27 Psoriatic spondylitis (Ankle and foot)	0.001	0.875	0.125
M07.26 Psoriatic spondylitis (Lower leg)	0.001	0.875	0.125
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.001	0.875	0.125
M07.24 Psoriatic spondylitis (Hand)	0.001	0.875	0.125
M07.23 Psoriatic spondylitis (Forearm)	0.001	0.875	0.125
M07.22 Psoriatic spondylitis (Upper arm)	0.001	0.875	0.125
M07.21 Psoriatic spondylitis (Shoulder region)	0.001	0.875	0.125
M07.20 Psoriatic spondylitis (Multiple sites)	0.001	0.875	0.125
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.001	0.875	0.125
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.001	0.875	0.125
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.001	0.875	0.125
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.001	0.875	0.125
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.001	0.875	0.125
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.001	0.875	0.125
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.001	0.875	0.125
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.001	0.875	0.125
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.001	0.875	0.125
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.001	0.875	0.125
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.001	0.875	0.125
M07.58 Arthropathy in ulcerative colitis (Other)	0.001	0.875	0.125
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.001	0.875	0.125
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.001	0.875	0.125
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.001	0.875	0.125
M07.54 Arthropathy in ulcerative colitis (Hand)	0.001	0.875	0.125
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.001	0.875	0.125
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.001	0.875	0.125
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.001	0.875	0.125
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.001	0.875	0.125
M07.69 Other enteropathic arthropathies (Site unspecified)	0.001	0.875	0.125
M07.68 Other enteropathic arthropathies (Other)	0.001	0.875	0.125
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.001	0.875	0.125
M07.66 Other enteropathic arthropathies (Lower leg)	0.001	0.875	0.125
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.001	0.875	0.125
M07.64 Other enteropathic arthropathies (Hand)	0.001	0.875	0.125
M07.63 Other enteropathic arthropathies (Forearm)	0.001	0.875	0.125
M07.62 Other enteropathic arthropathies (Upper arm)	0.001	0.875	0.125
M07.61 Other enteropathic arthropathies (Shoulder region)	0.001	0.875	0.125
M07.60 Other enteropathic arthropathies (Multiple sites)	0.001	0.875	0.125
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.876	0.124
G62.1 Alcoholic polyneuropathy	0.000	0.877	0.123
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.877	0.123
G64 Other disorders of peripheral nervous system	0.000	0.877	0.123
N39.3 Stress incontinence	0.121	0.879	0.000
G71 Primary disorders of muscles	0.000	0.879	0.121
G83.9 Paralytic syndrome, unspecified	0.000	0.880	0.120
D64.9 Anaemia, unspecified	0.000	0.881	0.119
G61.8 Other inflammatory polyneuropathies	0.000	0.882	0.118
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.882	0.118
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.887	0.113
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.887	0.113
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.887	0.113
D64 Other anaemias	0.000	0.888	0.112
G62.2 Polyneuropathy due to other toxic agents	0.000	0.888	0.111
L41.9 Parapsoriasis, unspecified	0.000	0.889	0.111
L41.8 Other parapsoriasis	0.000	0.889	0.111
L41.5 Retiform parapsoriasis	0.000	0.889	0.111
L41.4 Large plaque parapsoriasis	0.000	0.889	0.111
L41.3 Small plaque parapsoriasis	0.000	0.889	0.111
L41.2 Lymphomatoid papulosis	0.000	0.889	0.111
L41.1 Pityriasis lichenoides chronica	0.000	0.889	0.111
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.889	0.111
L44.9 Papulosquamous disorder, unspecified	0.000	0.889	0.111
L44.8 Other specified papulosquamous disorders	0.000	0.889	0.111
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.889	0.111
L44.3 Lichen ruber moniliformis	0.000	0.889	0.111
L44.2 Lichen striatus	0.000	0.889	0.111
L44.1 Lichen nitidus	0.000	0.889	0.111
L44.0 Pityriasis rubra pilaris	0.000	0.889	0.111
G60.0 Hereditary motor and sensory neuropathy	0.000	0.889	0.111
G81 Hemiplegia	0.000	0.889	0.111
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.891	0.109
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.891	0.109
G72 Other myopathies	0.000	0.892	0.108
G03.9 Meningitis, unspecified	0.000	0.893	0.107
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.893	0.107
G62.8 Other specified polyneuropathies	0.000	0.894	0.106
G06.1 Intraspinal abscess and granuloma	0.000	0.895	0.105
G06.0 Intracranial abscess and granuloma	0.000	0.895	0.105
G70 Myasthenia gravis and other myoneural disorders	0.000	0.895	0.105
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.895	0.105
G83.1 Monoplegia of lower limb	0.000	0.896	0.104
D50 Iron deficiency anaemia	0.000	0.897	0.103
G36.9 Acute disseminated demyelination, unspecified	0.000	0.898	0.102
G36.8 Other specified acute disseminated demyelination	0.000	0.898	0.102
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.898	0.102
D60-D64 Aplastic and other anaemias	0.000	0.898	0.102
D50-D53 Nutritional anaemias	0.000	0.898	0.102
G00.1 Pneumococcal meningitis	0.000	0.898	0.102
G83.5 Locked-in syndrome	0.000	0.899	0.101
G83.3 Monoplegia, unspecified	0.000	0.899	0.101
G83.0 Diplegia of upper limbs	0.000	0.899	0.101
D50.9 Iron deficiency anaemia, unspecified	0.000	0.900	0.100
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.900	0.100
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.902	0.098
G61.1 Serum neuropathy	0.000	0.903	0.097
D64.8 Other specified anaemias	0.000	0.903	0.097
D61 Other aplastic anaemias	0.000	0.904	0.096
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.905	0.095
G60.3 Idiopathic progressive neuropathy	0.000	0.905	0.095
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.905	0.095
G60.1 Refsum's disease	0.000	0.905	0.095
D61.9 Aplastic anaemia, unspecified	0.000	0.906	0.094
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.907	0.093
G00.9 Bacterial meningitis, unspecified	0.000	0.907	0.092
G82 Paraplegia and tetraplegia	0.000	0.907	0.093
G03.8 Meningitis due to other specified causes	0.000	0.908	0.092
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.908	0.092
G03.1 Chronic meningitis	0.000	0.908	0.092
G03.0 Nonpyogenic meningitis	0.000	0.908	0.092
G36.0 Neuromyelitis optica [Devic]	0.000	0.908	0.092
D50.8 Other iron deficiency anaemias	0.000	0.908	0.092
G06.2 Extradural and subdural abscess, unspecified	0.000	0.908	0.091
G81.1 Spastic hemiplegia	0.000	0.909	0.091
G61.0 Guillain-Barre syndrome	0.000	0.910	0.090
G00.8 Other bacterial meningitis	0.000	0.910	0.090
G00.3 Staphylococcal meningitis	0.000	0.910	0.090
G00.2 Streptococcal meningitis	0.000	0.910	0.090
G00.0 Haemophilus meningitis	0.000	0.910	0.090
G83.8 Other specified paralytic syndromes	0.000	0.910	0.090
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.910	0.090
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.910	0.089
D51 Vitamin B12 deficiency anaemia	0.000	0.911	0.089
G37 Other demyelinating diseases of central nervous system	0.000	0.912	0.088
D80-D89 Certain disorders involving the immune mechanism	0.000	0.913	0.087
G12 Spinal muscular atrophy and related syndromes	0.000	0.913	0.087
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.913	0.087
G71.9 Primary disorder of muscle, unspecified	0.000	0.913	0.087
G71.8 Other primary disorders of muscles	0.000	0.913	0.087
G71.2 Congenital myopathies	0.000	0.913	0.087
G71.1 Myotonic disorders	0.000	0.913	0.087
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.915	0.085
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.915	0.085
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.915	0.085
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.915	0.085
D52 Folate deficiency anaemia	0.000	0.915	0.085
G80 Infantile cerebral palsy	0.000	0.916	0.084
G72.9 Myopathy, unspecified	0.000	0.917	0.083
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.918	0.081
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.918	0.081
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.918	0.081
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.918	0.081
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.918	0.081
G63.1 Polyneuropathy in neoplastic disease	0.000	0.918	0.081
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.918	0.081
D64.4 Congenital dyserythropoietic anaemia	0.000	0.919	0.081
D64.3 Other sideroblastic anaemias	0.000	0.919	0.081
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.919	0.081
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.919	0.081
D64.0 Hereditary sideroblastic anaemia	0.000	0.919	0.081
G70.0 Myasthenia gravis	0.000	0.920	0.080
G81.0 Flaccid hemiplegia	0.000	0.920	0.079
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.921	0.079
G72.8 Other specified myopathies	0.000	0.921	0.079
G62.0 Drug-induced polyneuropathy	0.000	0.921	0.079
G72.0 Drug-induced myopathy	0.000	0.921	0.078
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.922	0.078
D80 Immunodeficiency with predominantly antibody defects	0.000	0.922	0.078
G71.0 Muscular dystrophy	0.000	0.922	0.078
G72.3 Periodic paralysis	0.000	0.922	0.078
G72.2 Myopathy due to other toxic agents	0.000	0.922	0.078
G72.1 Alcoholic myopathy	0.000	0.922	0.078
D53 Other nutritional anaemias	0.000	0.923	0.077
M45-M49 Spondylopathies	0.000	0.923	0.077
G73.7 Myopathy other diseases classified elsewhere	0.000	0.923	0.077
G73.6 Myopathy in metabolic diseases	0.000	0.923	0.077
G73.5 Myopathy in endocrine diseases	0.000	0.923	0.077
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.923	0.077
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.923	0.077
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.923	0.077
G73.1 Eaton-Lambert syndrome	0.000	0.923	0.077
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.923	0.077
G82.1 Spastic paraplegia	0.000	0.923	0.077
G70.8 Other specified myoneural disorders	0.000	0.924	0.076
G70.2 Congenital and developmental myasthenia	0.000	0.924	0.076
G70.1 Toxic myoneural disorders	0.000	0.924	0.076
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.925	0.075
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.926	0.074
D50.1 Sideropenic dysphagia	0.000	0.926	0.074
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.927	0.073
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.927	0.073
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.927	0.072
G11 Hereditary ataxia	0.000	0.928	0.072
D52.9 Folate deficiency anaemia, unspecified	0.000	0.928	0.072
G63.2 Diabetic polyneuropathy	0.000	0.928	0.072
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.928	0.072
G02.1 Meningitis in mycoses	0.000	0.928	0.072
G12.2 Motor neuron disease	0.000	0.929	0.071
G83.2 Monoplegia of upper limb	0.000	0.929	0.071
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.929	0.071
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.929	0.071
G04.1 Tropical spastic paraplegia	0.000	0.929	0.071
D61.8 Other specified aplastic anaemias	0.000	0.931	0.069
D61.3 Idiopathic aplastic anaemia	0.000	0.931	0.069
D61.2 Aplastic anaemia due to other external agents	0.000	0.931	0.069
G70.9 Myoneural disorder, unspecified	0.000	0.932	0.068
G14 Postpolio syndrome	0.000	0.932	0.068
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.932	0.068
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.933	0.067
G82.3 Flaccid tetraplegia	0.000	0.933	0.066
G82.0 Flaccid paraplegia	0.000	0.933	0.066
D86 Sarcoidosis	0.000	0.934	0.066
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.934	0.066
D61.0 Constitutional aplastic anaemia	0.000	0.935	0.065
D55-D59 Haemolytic anaemias	0.000	0.935	0.065
G82.4 Spastic tetraplegia	0.000	0.935	0.064
G82.5 Tetraplegia, unspecified	0.000	0.936	0.064
D51.2 Transcobalamin II deficiency	0.000	0.936	0.064
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.936	0.064
G81.9 Hemiplegia, unspecified	0.000	0.936	0.064
G80.2 Infantile hemiplegia	0.000	0.936	0.064
D83 Common variable immunodeficiency	0.000	0.936	0.063
G37.5 Concentric sclerosis [Balo]	0.000	0.937	0.063
G37.4 Subacute necrotising myelitis	0.000	0.937	0.063
G37.2 Central pontine myelinolysis	0.000	0.937	0.063
G37.1 Central demyelination of corpus callosum	0.000	0.937	0.063
G37.0 Diffuse sclerosis	0.000	0.937	0.063
L43 Lichen planus	0.001	0.937	0.062
D61.1 Drug-induced aplastic anaemia	0.000	0.937	0.063
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.937	0.063
D81 Combined immunodeficiencies	0.000	0.937	0.063
G12.9 Spinal muscular atrophy, unspecified	0.000	0.937	0.062
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.937	0.062
G12.1 Other inherited spinal muscular atrophy	0.000	0.937	0.062
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.937	0.062
G80.0 Spastic cerebral palsy	0.000	0.937	0.062
D84 Other immunodeficiencies	0.000	0.938	0.061
D52.8 Other folate deficiency anaemias	0.000	0.939	0.061
D52.1 Drug-induced folate deficiency anaemia	0.000	0.939	0.061
D52.0 Dietary folate deficiency anaemia	0.000	0.939	0.061
G80.8 Other infantile cerebral palsy	0.000	0.939	0.060
G80.4 Ataxic cerebral palsy	0.000	0.939	0.060
G80.3 Dyskinetic cerebral palsy	0.000	0.939	0.060
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.940	0.060
D53.9 Nutritional anaemia, unspecified	0.000	0.940	0.060
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.941	0.058
G10 Huntington's disease	0.000	0.941	0.058
R31 Unspecified haematuria	0.059	0.941	0.000
D86.3 Sarcoidosis of skin	0.000	0.941	0.059
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.941	0.059
D86.0 Sarcoidosis of lung	0.000	0.942	0.058
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.942	0.058
G04.0 Acute disseminated encephalitis	0.000	0.942	0.057
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.000	0.944	0.056
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.000	0.944	0.056
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.000	0.944	0.056
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.000	0.944	0.056
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.944	0.056
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.944	0.056
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.944	0.056
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.944	0.056
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.944	0.056
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.944	0.056
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.944	0.056
D53.8 Other specified nutritional anaemias	0.000	0.944	0.056
D53.2 Scorbutic anaemia	0.000	0.944	0.056
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.944	0.056
D53.0 Protein deficiency anaemia	0.000	0.944	0.056
D82 Immunodeficiency associated with other major defects	0.000	0.944	0.055
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.944	0.055
G11.4 Hereditary spastic paraplegia	0.000	0.945	0.055
M46 Other inflammatory spondylopathies	0.000	0.945	0.055
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.945	0.055
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.946	0.054
D89.1 Cryoglobulinaemia	0.000	0.946	0.054
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.947	0.053
D60.8 Other acquired pure red cell aplasias	0.000	0.947	0.053
D60.1 Transient acquired pure red cell aplasia	0.000	0.947	0.053
D60.0 Chronic acquired pure red cell aplasia	0.000	0.947	0.053
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.947	0.052
D89.3 Immune reconstitution syndrome	0.000	0.947	0.052
G80.1 Spastic diplegia	0.000	0.948	0.052
G11.8 Other hereditary ataxias	0.000	0.948	0.052
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.948	0.052
G11.2 Late-onset cerebellar ataxia	0.000	0.948	0.052
G11.0 Congenital nonprogressive ataxia	0.000	0.948	0.052
G20-G26 Extrapyramidal and movement disorders	0.000	0.949	0.051
D59 Acquired haemolytic anaemia	0.000	0.950	0.050
D84.9 Immunodeficiency, unspecified	0.000	0.950	0.050
D86.1 Sarcoidosis of lymph nodes	0.000	0.951	0.049
E00-E07 Disorders of thyroid gland	0.000	0.951	0.049
G11.1 Early-onset cerebellar ataxia	0.000	0.952	0.048
M49 Spondylopathies in diseases classified elsewhere	0.000	0.952	0.047
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.953	0.047
D83.9 Common variable immunodeficiency, unspecified	0.000	0.953	0.046
D55 Anaemia due to enzyme disorders	0.000	0.953	0.046
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.954	0.046
G11.9 Hereditary ataxia, unspecified	0.000	0.954	0.046
D62 Acute posthaemorrhagic anaemia	0.000	0.954	0.046
D83.8 Other common variable immunodeficiencies	0.000	0.954	0.046
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.954	0.046
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.954	0.046
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.954	0.046
L43.3 Subacute (active) lichen planus	0.001	0.955	0.044
L43.2 Lichenoid drug reaction	0.001	0.955	0.044
L43.1 Bullous lichen planus	0.001	0.955	0.044
L43.0 Hypertrophic lichen planus	0.001	0.955	0.044
D81.9 Combined immunodeficiency, unspecified	0.000	0.955	0.045
D81.8 Other combined immunodeficiencies	0.000	0.955	0.045
D81.7 Major histocompatibility complex class II deficiency	0.000	0.955	0.045
D81.6 Major histocompatibility complex class I deficiency	0.000	0.955	0.045
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.955	0.045
D81.4 Nezelof's syndrome	0.000	0.955	0.045
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.955	0.045
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.955	0.045
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.955	0.045
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.955	0.045
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.955	0.045
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.956	0.044
D58 Other hereditary haemolytic anaemias	0.000	0.956	0.044
D56 Thalassaemia	0.000	0.956	0.044
D57 Sickle-cell disorders	0.000	0.956	0.043
D84.1 Defects in the complement system	0.000	0.957	0.043
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.957	0.042
M46.0 Spinal enthesopathy	0.000	0.957	0.042
G90-G99 Other disorders of the nervous system	0.000	0.959	0.041
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.960	0.040
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.960	0.040
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.960	0.040
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.960	0.040
D82.2 Immunodeficiency with short-limbed stature	0.000	0.960	0.040
D82.0 Wiskott-Aldrich syndrome	0.000	0.960	0.040
M46.2 Osteomyelitis of vertebra	0.000	0.960	0.040
D59.1 Other autoimmune haemolytic anaemias	0.000	0.960	0.040
M46.8 Other specified inflammatory spondylopathies	0.000	0.960	0.040
M46.5 Other infective spondylopathies	0.000	0.960	0.040
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.961	0.039
G80.9 Infantile cerebral palsy, unspecified	0.000	0.962	0.038
E07 Other disorders of thyroid	0.000	0.962	0.038
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.962	0.038
G25 Other extrapyramidal and movement disorders	0.000	0.962	0.038
D86.9 Sarcoidosis, unspecified	0.000	0.963	0.037
G21 Secondary Parkinsonism	0.000	0.963	0.037
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.963	0.037
G22 Parkinsonism in diseases classified elsewhere	0.000	0.963	0.037
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.963	0.037
D59.8 Other acquired haemolytic anaemias	0.000	0.964	0.036
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.964	0.036
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.964	0.036
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.964	0.036
D59.3 Haemolytic-uraemic syndrome	0.000	0.964	0.036
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.964	0.036
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.964	0.036
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.964	0.036
D84.8 Other specified immunodeficiencies	0.000	0.964	0.036
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.964	0.036
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.965	0.035
E00 Congenital iodine-deficiency syndrome	0.000	0.965	0.035
E07.8 Other specified disorders of thyroid	0.000	0.965	0.035
M48 Other spondylopathies	0.000	0.965	0.035
G23 Other degenerative diseases of basal ganglia	0.000	0.965	0.034
G93 Other disorders of brain	0.000	0.965	0.035
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.966	0.034
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.966	0.034
M49.4 Neuropathic spondylopathy	0.000	0.966	0.034
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.966	0.034
M49.2 Enterobacterial spondylitis	0.000	0.966	0.034
M49.1 Brucella spondylitis	0.000	0.966	0.034
M49.0 Tuberculosis of spine	0.000	0.966	0.034
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.966	0.034
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.966	0.034
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.966	0.034
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.966	0.034
K75 Other inflammatory liver diseases	0.000	0.966	0.034
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.966	0.034
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.966	0.033
D55.8 Other anaemias due to enzyme disorders	0.000	0.966	0.033
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.966	0.033
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.966	0.033
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.966	0.033
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.966	0.033
G93.0 Cerebral cysts	0.000	0.966	0.034
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.966	0.033
M46.06 Spinal enthesopathy (Lumbar region)	0.000	0.967	0.033
K75.8 Other specified inflammatory liver diseases	0.000	0.967	0.033
G82.2 Paraplegia, unspecified	0.000	0.967	0.033
D82.1 Di George's syndrome	0.000	0.967	0.033
D58.0 Hereditary spherocytosis	0.000	0.967	0.033
D56.1 Beta thalassaemia	0.000	0.968	0.032
K75.4 Autoimmune hepatitis	0.000	0.968	0.032
K75.0 Abscess of liver	0.000	0.968	0.032
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.968	0.032
D58.1 Hereditary elliptocytosis	0.000	0.968	0.032
D56.9 Thalassaemia, unspecified	0.000	0.968	0.031
D56.8 Other thalassaemias	0.000	0.968	0.031
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.968	0.031
D56.2 Delta-beta thalassaemia	0.000	0.968	0.031
D56.0 Alpha thalassaemia	0.000	0.968	0.031
D57.8 Other sickle-cell disorders	0.000	0.968	0.031

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations