TreeWAS – Variant ID: rs7755802

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E03 Other hypothyroidism	0.000	0.005	0.995
E03.9 Hypothyroidism, unspecified	0.000	0.006	0.994
E05.9 Thyrotoxicosis, unspecified	0.000	0.009	0.991
L40.0 Psoriasis vulgaris	0.978	0.022	0.000
G35 Multiple sclerosis	0.000	0.047	0.953
E06 Thyroiditis	0.000	0.066	0.934
K90 Intestinal malabsorption	0.000	0.111	0.889
E06.3 Autoimmune thyroiditis	0.000	0.148	0.852
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.162	0.838
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.194	0.806
E06.9 Thyroiditis, unspecified	0.000	0.197	0.803
L40.1 Generalised pustular psoriasis	0.762	0.238	0.000
E03.8 Other specified hypothyroidism	0.000	0.256	0.744
E53.8 Deficiency of other specified B group vitamins	0.000	0.257	0.743
E53 Deficiency of other B group vitamins	0.000	0.260	0.740
E50-E64 Other nutritional deficiencies	0.000	0.268	0.732
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.270	0.730
K90.9 Intestinal malabsorption, unspecified	0.000	0.276	0.724
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
E03.5 Myxoedema coma	0.000	0.287	0.713
E03.4 Atrophy of thyroid (acquired)	0.000	0.287	0.713
E03.3 Postinfectious hypothyroidism	0.000	0.287	0.713
L40.4 Guttate psoriasis	0.711	0.289	0.000
K90.8 Other intestinal malabsorption	0.000	0.291	0.709
L40.8 Other psoriasis	0.697	0.302	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.308	0.692
E06.5 Other chronic thyroiditis	0.000	0.328	0.672
E06.4 Drug-induced thyroiditis	0.000	0.330	0.670
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.330	0.670
E06.0 Acute thyroiditis	0.000	0.330	0.670
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.339	0.661
E03.1 Congenital hypothyroidism without goitre	0.000	0.341	0.659
L40.3 Pustulosis palmaris et plantaris	0.658	0.342	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.345	0.655
G37 Other demyelinating diseases of central nervous system	0.000	0.361	0.639
K90.3 Pancreatic steatorrhoea	0.000	0.362	0.638
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.362	0.638
K90.1 Tropical sprue	0.000	0.362	0.638
E06.1 Subacute thyroiditis	0.000	0.364	0.636
E07 Other disorders of thyroid	0.000	0.365	0.635
E04 Other non-toxic goitre	0.000	0.383	0.617
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.390	0.610
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.421	0.579
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.431	0.569
E58 Dietary calcium deficiency	0.000	0.441	0.559
E05.8 Other thyrotoxicosis	0.000	0.444	0.556
E51 Thiamine deficiency	0.000	0.453	0.547
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.459	0.540
E04.0 Non-toxic diffuse goitre	0.000	0.468	0.532
E53.1 Pyridoxine deficiency	0.000	0.469	0.531
E53.0 Riboflavin deficiency	0.000	0.469	0.531
E56 Other vitamin deficiencies	0.000	0.474	0.526
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.475	0.525
E63 Other nutritional deficiencies	0.000	0.475	0.525
E50 Vitamin A deficiency	0.000	0.475	0.525
E60 Dietary zinc deficiency	0.000	0.475	0.525
E59 Dietary selenium deficiency	0.000	0.475	0.525
E52 Niacin deficiency [pellagra]	0.000	0.475	0.525
E61 Deficiency of other nutrient elements	0.000	0.485	0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.487	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.487	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.487	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.487	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.487	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.487	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.487	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.487	0.513
E04.2 Non-toxic multinodular goitre	0.000	0.491	0.509
E40-E46 Malnutrition	0.000	0.497	0.503
E54 Ascorbic acid deficiency	0.000	0.497	0.503
G36 Other acute disseminated demyelination	0.000	0.504	0.496
E07.8 Other specified disorders of thyroid	0.000	0.524	0.476
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.542	0.458
G37.5 Concentric sclerosis [Balo]	0.000	0.542	0.458
G37.4 Subacute necrotising myelitis	0.000	0.542	0.458
G37.2 Central pontine myelinolysis	0.000	0.542	0.458
G37.1 Central demyelination of corpus callosum	0.000	0.542	0.458
G37.0 Diffuse sclerosis	0.000	0.542	0.458
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.544	0.456
E07.1 Dyshormogenetic goitre	0.000	0.545	0.455
E07.0 Hypersecretion of calcitonin	0.000	0.545	0.455
E04.8 Other specified non-toxic goitre	0.000	0.557	0.442
E55 Vitamin D deficiency	0.000	0.569	0.431
E51.2 Wernicke's encephalopathy	0.000	0.586	0.413
L40-L45 Papulosquamous disorders	0.404	0.596	0.000
E70-E90 Metabolic disorders	0.000	0.600	0.400
E89.0 Postprocedural hypothyroidism	0.000	0.602	0.398
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.606	0.394
E51.9 Thiamine deficiency, unspecified	0.000	0.608	0.392
E51.8 Other manifestations of thiamine deficiency	0.000	0.608	0.392
E51.1 Beriberi	0.000	0.608	0.392
E61.1 Iron deficiency	0.000	0.622	0.378
E56.1 Deficiency of vitamin K	0.000	0.622	0.378
E56.9 Vitamin deficiency, unspecified	0.000	0.623	0.377
E56.8 Deficiency of other vitamins	0.000	0.623	0.377
E56.0 Deficiency of vitamin E	0.000	0.623	0.377
E50.9 Vitamin A deficiency, unspecified	0.000	0.623	0.377
E50.8 Other manifestations of vitamin A deficiency	0.000	0.623	0.377
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.623	0.377
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.623	0.377
E50.5 Vitamin A deficiency with night blindness	0.000	0.623	0.377
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.623	0.377
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.623	0.377
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.623	0.377
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.623	0.377
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.623	0.377
E63.9 Nutritional deficiency, unspecified	0.000	0.623	0.377
E63.8 Other specified nutritional deficiencies	0.000	0.623	0.377
E63.1 Imbalance of constituents of food intake	0.000	0.623	0.377
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.623	0.377
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.623	0.377
E64.8 Sequelae of other nutritional deficiencies	0.000	0.623	0.377
E64.3 Sequelae of rickets	0.000	0.623	0.377
E64.2 Sequelae of vitamin C deficiency	0.000	0.623	0.377
E64.1 Sequelae of vitamin A deficiency	0.000	0.623	0.377
E64.0 Sequelae of protein-energy malnutrition	0.000	0.623	0.377
E83.1 Disorders of iron metabolism	0.000	0.624	0.376
E83 Disorders of mineral metabolism	0.000	0.628	0.372
E61.9 Deficiency of nutrient element, unspecified	0.000	0.631	0.369
E61.8 Deficiency of other specified nutrient elements	0.000	0.631	0.369
E61.7 Deficiency of multiple nutrient elements	0.000	0.631	0.369
E61.6 Vanadium deficiency	0.000	0.631	0.369
E61.5 Molybdenum deficiency	0.000	0.631	0.369
E61.4 Chromium deficiency	0.000	0.631	0.369
E61.3 Manganese deficiency	0.000	0.631	0.369
E61.0 Copper deficiency	0.000	0.631	0.369
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.639	0.361
E45 Retarded development following protein-energy malnutrition	0.000	0.639	0.361
E43 Unspecified severe protein-energy malnutrition	0.000	0.639	0.361
E42 Marasmic kwashiorkor	0.000	0.639	0.361
E41 Nutritional marasmus	0.000	0.639	0.361
E40 Kwashiorkor	0.000	0.639	0.361
G36.9 Acute disseminated demyelination, unspecified	0.000	0.644	0.355
G36.8 Other specified acute disseminated demyelination	0.000	0.644	0.355
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.644	0.355
G36.0 Neuromyelitis optica [Devic]	0.000	0.645	0.355
E61.2 Magnesium deficiency	0.000	0.652	0.348
E07.9 Disorder of thyroid, unspecified	0.000	0.658	0.341
E46 Unspecified protein-energy malnutrition	0.000	0.659	0.340
E04.9 Non-toxic goitre, unspecified	0.000	0.672	0.328
E65-E68 Obesity and other hyperalimentation	0.000	0.673	0.327
E15 Nondiabetic hypoglycaemic coma	0.000	0.673	0.327
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.689	0.311
E55.0 Rickets, active	0.000	0.691	0.309
L42 Pityriasis rosea	0.301	0.699	0.000
L44 Other papulosquamous disorders	0.299	0.701	0.000
E84 Cystic fibrosis	0.000	0.709	0.291
L41 Parapsoriasis	0.289	0.710	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.289	0.710	0.000
E77 Disorders of glycoprotein metabolism	0.000	0.713	0.287
E76 Disorders of glycosaminoglycan metabolism	0.000	0.713	0.287
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.713	0.287
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.713	0.287
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.714	0.286
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.715	0.285
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.717	0.282
E89.1 Postprocedural hypoinsulinaemia	0.000	0.717	0.282
E10-E14 Diabetes mellitus	0.000	0.723	0.277
E79 Disorders of purine and pyrimidine metabolism	0.000	0.723	0.277
E70 Disorders of aromatic amino-acid metabolism	0.000	0.725	0.275
E88 Other metabolic disorders	0.000	0.729	0.271
E85 Amyloidosis	0.000	0.731	0.269
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.733	0.266
E83.8 Other disorders of mineral metabolism	0.000	0.733	0.266
E83.2 Disorders of zinc metabolism	0.000	0.733	0.266
E83.0 Disorders of copper metabolism	0.000	0.733	0.266
R31 Unspecified haematuria	0.262	0.738	0.000
E89.4 Postprocedural ovarian failure	0.000	0.739	0.261
E80.4 Gilbert's syndrome	0.000	0.740	0.260
E73 Lactose intolerance	0.000	0.740	0.260
E16 Other disorders of pancreatic internal secretion	0.000	0.741	0.259
E44.1 Mild protein-energy malnutrition	0.000	0.741	0.259
E44.0 Moderate protein-energy malnutrition	0.000	0.741	0.259
E72 Other disorders of amino-acid metabolism	0.000	0.742	0.258
L43 Lichen planus	0.256	0.744	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.746	0.254
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.748	0.252
E74 Other disorders of carbohydrate metabolism	0.000	0.751	0.249
E10 Insulin-dependent diabetes mellitus	0.000	0.758	0.242
E89.5 Postprocedural testicular hypofunction	0.000	0.759	0.240
E10.9 Without complications	0.000	0.760	0.240
E80.1 Porphyria cutanea tarda	0.000	0.762	0.238
E67 Other hyperalimentation	0.000	0.765	0.235
E68 Sequelae of hyperalimentation	0.000	0.765	0.235
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.766	0.234
E89.3 Postprocedural hypopituitarism	0.000	0.768	0.232
E65 Localised adiposity	0.000	0.774	0.226
L44.0 Pityriasis rubra pilaris	0.225	0.775	0.000
E80.6 Other disorders of bilirubin metabolism	0.000	0.776	0.224
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.777	0.223
E80.5 Crigler-Najjar syndrome	0.000	0.777	0.223
E80.3 Defects of catalase and peroxydase	0.000	0.777	0.223
E80.0 Hereditary erythropoietic porphyria	0.000	0.777	0.223
L44.9 Papulosquamous disorder, unspecified	0.215	0.785	0.000
L44.8 Other specified papulosquamous disorders	0.215	0.785	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.215	0.785	0.000
L44.3 Lichen ruber moniliformis	0.215	0.785	0.000
L44.2 Lichen striatus	0.215	0.785	0.000
L44.1 Lichen nitidus	0.215	0.785	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.786	0.214
E84.9 Cystic fibrosis, unspecified	0.000	0.788	0.212
E20-E35 Disorders of other endocrine glands	0.000	0.790	0.210
E10.3 With ophthalmic complications	0.000	0.790	0.210
E84.8 Cystic fibrosis with other manifestations	0.000	0.791	0.209
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.791	0.209
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.791	0.209
L41.9 Parapsoriasis, unspecified	0.208	0.792	0.000
L41.8 Other parapsoriasis	0.208	0.792	0.000
L41.5 Retiform parapsoriasis	0.208	0.792	0.000
L41.4 Large plaque parapsoriasis	0.208	0.792	0.000
L41.3 Small plaque parapsoriasis	0.208	0.792	0.000
L41.2 Lymphomatoid papulosis	0.208	0.792	0.000
L41.1 Pityriasis lichenoides chronica	0.208	0.792	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.208	0.792	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.792	0.208
E71.3 Disorders of fatty-acid metabolism	0.000	0.794	0.206
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.794	0.206
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.794	0.206
E71.0 Maple-syrup-urine disease	0.000	0.794	0.206
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.794	0.206
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.794	0.206
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.794	0.206
E76.2 Other mucopolysaccharidoses	0.000	0.794	0.206
E76.1 Mucopolysaccharidosis, type II	0.000	0.794	0.206
E76.0 Mucopolysaccharidosis, type I	0.000	0.794	0.206
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.794	0.206
E77.8 Other disorders of glycoprotein metabolism	0.000	0.794	0.206
E77.1 Defects in glycoprotein degradation	0.000	0.794	0.206
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.794	0.206
E85.4 Organ-limited amyloidosis	0.000	0.794	0.206
E88.3 Tumour lysis syndrome	0.000	0.800	0.199
E12 Malnutrition-related diabetes mellitus	0.000	0.801	0.199
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.801	0.199
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.801	0.199
E79.1 Lesch-Nyhan syndrome	0.000	0.801	0.199
E85.8 Other amyloidosis	0.000	0.801	0.199
E27.1 Primary adrenocortical insufficiency	0.000	0.802	0.198
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.803	0.197
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.803	0.197
E70.2 Disorders of tyrosine metabolism	0.000	0.803	0.197
E70.1 Other hyperphenylalaninaemias	0.000	0.803	0.197
E70.0 Classical phenylketonuria	0.000	0.803	0.197
E83.3 Disorders of phosphorus metabolism	0.000	0.804	0.196
E27 Other disorders of adrenal gland	0.000	0.805	0.195
E10.2 With renal complications	0.000	0.806	0.194
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.807	0.193
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.807	0.193
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.807	0.193
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.811	0.189
E73.8 Other lactose intolerance	0.000	0.814	0.186
E73.1 Secondary lactase deficiency	0.000	0.814	0.186
E73.0 Congenital lactase deficiency	0.000	0.814	0.186
E88.9 Metabolic disorder, unspecified	0.000	0.814	0.186
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.814	0.186
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.814	0.186
E16.4 Abnormal secretion of gastrin	0.000	0.814	0.186
E16.3 Increased secretion of glucagon	0.000	0.814	0.186
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.815	0.185
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.815	0.185
E72.5 Disorders of glycine metabolism	0.000	0.815	0.185
E72.4 Disorders of ornithine metabolism	0.000	0.815	0.185
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.815	0.185
E72.2 Disorders of urea cycle metabolism	0.000	0.815	0.185
E70.3 Albinism	0.000	0.815	0.185
L43.8 Other lichen planus	0.185	0.815	0.000
L43.3 Subacute (active) lichen planus	0.184	0.816	0.000
L43.2 Lichenoid drug reaction	0.184	0.816	0.000
L43.1 Bullous lichen planus	0.184	0.816	0.000
L43.0 Hypertrophic lichen planus	0.184	0.816	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.819	0.181
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.819	0.181
E75.3 Sphingolipidosis, unspecified	0.000	0.819	0.181
E75.1 Other gangliosidosis	0.000	0.819	0.181
E75.0 GM2 gangliosidosis	0.000	0.819	0.181
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.821	0.179
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.821	0.179
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.821	0.179
E74.2 Disorders of galactose metabolism	0.000	0.821	0.179
E74.1 Disorders of fructose metabolism	0.000	0.821	0.179
E74.0 Glycogen storage disease	0.000	0.821	0.179
E72.0 Disorders of amino-acid transport	0.000	0.822	0.178
E85.3 Secondary systemic amyloidosis	0.000	0.823	0.177
E88.8 Other specified metabolic disorders	0.000	0.824	0.176
E80.2 Other porphyria	0.000	0.824	0.176
E75.5 Other lipid storage disorders	0.000	0.829	0.171
E85.9 Amyloidosis, unspecified	0.000	0.830	0.170
E88.2 Lipomatosis, not elsewhere classified	0.000	0.831	0.169
E67.8 Other specified hyperalimentation	0.000	0.831	0.168
E67.3 Hypervitaminosis D	0.000	0.831	0.168
E67.2 Megavitamin-B6 syndrome	0.000	0.831	0.168
E67.1 Hypercarotenaemia	0.000	0.831	0.168
E67.0 Hypervitaminosis A	0.000	0.831	0.168
E10.5 With peripheral circulatory complications	0.000	0.833	0.167
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.835	0.165
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.837	0.163
E29 Testicular dysfunction	0.000	0.838	0.162
E22 Hyperfunction of pituitary gland	0.000	0.838	0.162
E13 Other specified diabetes mellitus	0.000	0.839	0.160
E20 Hypoparathyroidism	0.000	0.841	0.159
E73.9 Lactose intolerance, unspecified	0.000	0.841	0.159
E75.2 Other sphingolipidosis	0.000	0.841	0.158
E10.7 With multiple complications	0.000	0.845	0.155
E31 Polyglandular dysfunction	0.000	0.846	0.154
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.849	0.151
E32 Diseases of thymus	0.000	0.849	0.151
E30 Disorders of puberty, not elsewhere classified	0.000	0.849	0.151
L43.9 Lichen planus, unspecified	0.149	0.851	0.000
E22.1 Hyperprolactinaemia	0.000	0.854	0.146
E16.1 Other hypoglycaemia	0.000	0.857	0.143
E12.9 Without complications	0.000	0.857	0.143
E12.8 With unspecified complications	0.000	0.857	0.143
E12.7 With multiple complications	0.000	0.857	0.143
E12.6 With other specified complications	0.000	0.857	0.143
E12.5 With peripheral circulatory complications	0.000	0.857	0.143
E12.4 With neurological complications	0.000	0.857	0.143
E12.3 With ophthalmic complications	0.000	0.857	0.143
E12.2 With renal complications	0.000	0.857	0.143
E12.1 With ketoacidosis	0.000	0.857	0.143
E12.0 With coma	0.000	0.857	0.143
E10.1 With ketoacidosis	0.000	0.859	0.141
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.859	0.140
E27.5 Adrenomedullary hyperfunction	0.000	0.860	0.140
E27.0 Other adrenocortical overactivity	0.000	0.860	0.140
E14 Unspecified diabetes mellitus	0.000	0.862	0.138
E10.8 With unspecified complications	0.000	0.862	0.138
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.865	0.135
E26 Hyperaldosteronism	0.000	0.866	0.134
E25 Adrenogenital disorders	0.000	0.866	0.134
E10.6 With other specified complications	0.000	0.866	0.133
E16.2 Hypoglycaemia, unspecified	0.000	0.867	0.133
E20.9 Hypoparathyroidism, unspecified	0.000	0.867	0.133
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.868	0.132
E14.3 With ophthalmic complications	0.000	0.870	0.130
E29.1 Testicular hypofunction	0.000	0.872	0.128
E27.2 Addisonian crisis	0.000	0.873	0.126
E28 Ovarian dysfunction	0.000	0.877	0.122
E22.0 Acromegaly and pituitary gigantism	0.000	0.878	0.122
E10.4 With neurological complications	0.000	0.882	0.118
E29.9 Testicular dysfunction, unspecified	0.000	0.883	0.117
E29.8 Other testicular dysfunction	0.000	0.883	0.117
E29.0 Testicular hyperfunction	0.000	0.883	0.117
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.884	0.116
E22.8 Other hyperfunction of pituitary gland	0.000	0.884	0.116
E13.8 With unspecified complications	0.000	0.885	0.115
E13.7 With multiple complications	0.000	0.885	0.115
E13.6 With other specified complications	0.000	0.885	0.115
E13.5 With peripheral circulatory complications	0.000	0.885	0.115
E13.4 With neurological complications	0.000	0.885	0.115
E13.3 With ophthalmic complications	0.000	0.885	0.115
E13.2 With renal complications	0.000	0.885	0.115
E13.1 With ketoacidosis	0.000	0.885	0.115
E13.0 With coma	0.000	0.885	0.115
E20.8 Other hypoparathyroidism	0.000	0.886	0.114
E20.0 Idiopathic hypoparathyroidism	0.000	0.886	0.114
E10.0 With coma	0.000	0.886	0.113
E31.0 Autoimmune polyglandular failure	0.000	0.887	0.113
E34 Other endocrine disorders	0.000	0.889	0.111
E31.9 Polyglandular dysfunction, unspecified	0.000	0.890	0.110
E31.8 Other polyglandular dysfunction	0.000	0.890	0.110
E31.1 Polyglandular hyperfunction	0.000	0.890	0.110
E30.9 Disorder of puberty, unspecified	0.000	0.892	0.108
E30.8 Other disorders of puberty	0.000	0.892	0.108
E30.1 Precocious puberty	0.000	0.892	0.108
E30.0 Delayed puberty	0.000	0.892	0.108
E32.9 Disease of thymus, unspecified	0.000	0.892	0.108
E32.8 Other diseases of thymus	0.000	0.892	0.108
E32.1 Abscess of thymus	0.000	0.892	0.108
E32.0 Persistent hyperplasia of thymus	0.000	0.892	0.108
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.892	0.108
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.892	0.108
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.892	0.108
E83.5 Disorders of calcium metabolism	0.000	0.894	0.106
E83.4 Disorders of magnesium metabolism	0.000	0.898	0.102
E14.6 With other specified complications	0.000	0.898	0.102
E27.9 Disorder of adrenal gland, unspecified	0.000	0.899	0.101
E28.3 Primary ovarian failure	0.000	0.899	0.101
E14.7 With multiple complications	0.000	0.901	0.099
E14.0 With coma	0.000	0.901	0.099
E20.1 Pseudohypoparathyroidism	0.000	0.902	0.098
E14.8 With unspecified complications	0.000	0.903	0.097
E26.9 Hyperaldosteronism, unspecified	0.000	0.904	0.096
E26.8 Other hyperaldosteronism	0.000	0.904	0.096
E26.1 Secondary hyperaldosteronism	0.000	0.904	0.096
E25.9 Adrenogenital disorder, unspecified	0.000	0.904	0.096
E25.8 Other adrenogenital disorders	0.000	0.904	0.096
E14.5 With peripheral circulatory complications	0.000	0.904	0.095
E24 Cushing's syndrome	0.001	0.909	0.091
E23 Hypofunction and other disorders of pituitary gland	0.000	0.912	0.088
E28.9 Ovarian dysfunction, unspecified	0.000	0.912	0.088
E28.8 Other ovarian dysfunction	0.000	0.912	0.088
E28.1 Androgen excess	0.000	0.912	0.088
E28.0 Oestrogen excess	0.000	0.912	0.088
E14.2 Withrenal complications	0.000	0.916	0.084
E14.1 With ketoacidosis	0.000	0.916	0.084
E34.0 Carcinoid syndrome	0.000	0.918	0.082
E34.5 Androgen resistance syndrome	0.000	0.920	0.080
E34.4 Constitutional tall stature	0.000	0.920	0.080
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.920	0.080
E34.1 Other hypersecretion of intestinal hormones	0.000	0.920	0.080
E34.3 Short stature, not elsewhere classified	0.000	0.920	0.080
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.921	0.079
E26.0 Primary hyperaldosteronism	0.000	0.921	0.079
E86 Volume depletion	0.000	0.922	0.078
E13.9 Without complications	0.000	0.923	0.077
E27.8 Other specified disorders of adrenal gland	0.000	0.925	0.074
E14.4 With neurological complications	0.000	0.926	0.074
E04.1 Non-toxic single thyroid nodule	0.000	0.927	0.073
K90-K93 Other diseases of the digestive system	0.000	0.933	0.067
E24.0 Pituitary-dependent Cushing's disease	0.001	0.933	0.066
E23.7 Disorder of pituitary gland, unspecified	0.000	0.933	0.066
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.934	0.065
E24.3 Ectopic ACTH syndrome	0.001	0.934	0.065
E24.1 Nelson's syndrome	0.001	0.934	0.065
E34.8 Other specified endocrine disorders	0.000	0.935	0.065
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.936	0.063
E23.1 Drug-induced hypopituitarism	0.000	0.936	0.063
E66 Obesity	0.000	0.937	0.063
E24.2 Drug-induced Cushing's syndrome	0.001	0.937	0.062
F41.9 Anxiety disorder, unspecified	0.061	0.939	0.000
E24.8 Other Cushing's syndrome	0.001	0.939	0.060
E34.9 Endocrine disorder, unspecified	0.000	0.940	0.060
E23.2 Diabetes insipidus	0.000	0.943	0.057
E23.6 Other disorders of pituitary gland	0.000	0.944	0.056
F41 Other anxiety disorders	0.055	0.945	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.945	0.055
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.054	0.946	0.000
F41.2 Mixed anxiety and depressive disorder	0.053	0.947	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.952	0.048
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.952	0.048
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.952	0.048
E66.1 Drug-induced obesity	0.000	0.955	0.045
J47 Bronchiectasis	0.000	0.958	0.042
E66.8 Other obesity	0.000	0.959	0.041
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.960	0.040
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.961	0.039
F41.8 Other specified anxiety disorders	0.038	0.962	0.000
E21.2 Other hyperparathyroidism	0.000	0.963	0.036
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.965	0.035
K93.1 Megacolon in Chagas' disease	0.000	0.965	0.035
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.965	0.035
E21.4 Other specified disorders of parathyroid gland	0.000	0.967	0.033
F41.3 Other mixed anxiety disorders	0.031	0.969	0.000
E66.0 Obesity due to excess calories	0.000	0.970	0.029
E23.0 Hypopituitarism	0.000	0.972	0.028
M35 Other systemic involvement of connective tissue	0.000	0.972	0.028
E24.9 Cushing's syndrome, unspecified	0.002	0.975	0.024
E28.2 Polycystic ovarian syndrome	0.001	0.976	0.024
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.976	0.023
R30-R39 Symptoms and signs involving the urinary system	0.023	0.977	0.000
M35.7 Hypermobility syndrome	0.000	0.977	0.023
C32.0 Glottis	0.022	0.978	0.000
M35.1 Other overlap syndromes	0.000	0.978	0.022
R30 Pain associated with micturition	0.021	0.979	0.000
M35.2 Behcet's disease	0.000	0.979	0.021
R30.0 Dysuria	0.021	0.979	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.980	0.020
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.980	0.020
M35.5 Multifocal fibrosclerosis	0.000	0.980	0.020
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.980	0.020
R34 Anuria and oliguria	0.020	0.980	0.000
M35.3 Polymyalgia rheumatica	0.000	0.980	0.020
M35.8 Other specified systemic involvement of connective tissue	0.000	0.981	0.019
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.982	0.018
R30.1 Vesical tenesmus	0.017	0.982	0.000
D23.1 Skin of eyelid, including canthus	0.000	0.982	0.018
Q61 Cystic kidney disease	0.017	0.983	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.983	0.017
Q61.3 Polycystic kidney, unspecified	0.017	0.983	0.000
Q61.2 Polycystic kidney, adult type	0.017	0.983	0.000
Q61.0 Congenital single renal cyst	0.016	0.984	0.000
R39 Other symptoms and signs involving the urinary system	0.015	0.985	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.985	0.015
E87.0 Hyperosmolality and hypernatraemia	0.000	0.985	0.015
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.986	0.014
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.986	0.014
F41.1 Generalised anxiety disorder	0.014	0.986	0.000
R35 Polyuria	0.014	0.986	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.986	0.014
C32 Malignant neoplasm of larynx	0.014	0.986	0.000
R36 Urethral discharge	0.013	0.987	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.013	0.987	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.987	0.013
Q61.4 Renal dysplasia	0.013	0.987	0.000
Q61.9 Cystic kidney disease, unspecified	0.013	0.987	0.000
E87.6 Hypokalaemia	0.000	0.987	0.013
Q61.8 Other cystic kidney diseases	0.013	0.987	0.000
Q61.1 Polycystic kidney, infantile type	0.013	0.987	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations