TreeWAS – Variant ID: rs7759127

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
L40 Psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.109	0.891
L40.4 Guttate psoriasis	0.000	0.283	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.283	0.716
L40.2 Acrodermatitis continua	0.000	0.283	0.716
L40.1 Generalised pustular psoriasis	0.000	0.283	0.716
L40.8 Other psoriasis	0.000	0.328	0.672
E03 Other hypothyroidism	0.498	0.501	0.001
K90 Intestinal malabsorption	0.000	0.550	0.450
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.410	0.590	0.000
L40-L45 Papulosquamous disorders	0.000	0.600	0.400
E03.5 Myxoedema coma	0.357	0.642	0.001
E03.4 Atrophy of thyroid (acquired)	0.357	0.642	0.001
E03.3 Postinfectious hypothyroidism	0.357	0.642	0.001
E03.1 Congenital hypothyroidism without goitre	0.357	0.642	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.357	0.642	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.646	0.354
E03.8 Other specified hypothyroidism	0.327	0.673	0.001
K90.3 Pancreatic steatorrhoea	0.000	0.677	0.323
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.677	0.323
K90.1 Tropical sprue	0.000	0.677	0.323
K90.8 Other intestinal malabsorption	0.000	0.682	0.318
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.704	0.296
L43 Lichen planus	0.000	0.713	0.287
L44 Other papulosquamous disorders	0.000	0.713	0.287
L41 Parapsoriasis	0.000	0.713	0.287
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.713	0.287
L42 Pityriasis rosea	0.000	0.722	0.277
L43.8 Other lichen planus	0.000	0.783	0.217
L43.3 Subacute (active) lichen planus	0.000	0.794	0.206
L43.2 Lichenoid drug reaction	0.000	0.794	0.206
L43.1 Bullous lichen planus	0.000	0.794	0.206
L43.0 Hypertrophic lichen planus	0.000	0.794	0.206
L41.9 Parapsoriasis, unspecified	0.000	0.794	0.206
L41.8 Other parapsoriasis	0.000	0.794	0.206
L41.5 Retiform parapsoriasis	0.000	0.794	0.206
L41.4 Large plaque parapsoriasis	0.000	0.794	0.206
L41.3 Small plaque parapsoriasis	0.000	0.794	0.206
L41.2 Lymphomatoid papulosis	0.000	0.794	0.206
L41.1 Pityriasis lichenoides chronica	0.000	0.794	0.206
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.794	0.206
L44.9 Papulosquamous disorder, unspecified	0.000	0.794	0.206
L44.8 Other specified papulosquamous disorders	0.000	0.794	0.206
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.794	0.206
L44.3 Lichen ruber moniliformis	0.000	0.794	0.206
L44.2 Lichen striatus	0.000	0.794	0.206
L44.1 Lichen nitidus	0.000	0.794	0.206
L44.0 Pityriasis rubra pilaris	0.000	0.794	0.206
L43.9 Lichen planus, unspecified	0.000	0.807	0.193
I84.9 Unspecified haemorrhoids without complication	0.078	0.922	0.000
M25.5 Pain in joint	0.000	0.924	0.076
M25.51 Pain in joint (Shoulder region)	0.000	0.924	0.076
M25.54 Pain in joint (Hand)	0.000	0.926	0.074
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.933	0.067
M25.59 Pain in joint (Site unspecified)	0.000	0.935	0.065
M25.58 Pain in joint (Other)	0.000	0.938	0.062
M25 Other joint disorders, not elsewhere classified	0.000	0.941	0.059
M25.9 Joint disorder, unspecified	0.000	0.947	0.053
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.948	0.052
M25.50 Pain in joint (Multiple sites)	0.000	0.948	0.052
M25.56 Pain in joint (Lower leg)	0.000	0.948	0.052
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.950	0.050
M25.7 Osteophyte	0.000	0.950	0.050
M25.57 Pain in joint (Ankle and foot)	0.000	0.950	0.050
M25.52 Pain in joint (Upper arm)	0.000	0.951	0.049
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.952	0.048
M25.53 Pain in joint (Forearm)	0.000	0.952	0.048
M25.8 Other specified joint disorders	0.000	0.956	0.044
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.957	0.043
M25.2 Flail joint	0.000	0.957	0.043
M25.1 Fistula of joint	0.000	0.957	0.043
M25.71 Osteophyte (Shoulder region)	0.000	0.958	0.042
M25.76 Osteophyte (Lower leg)	0.000	0.958	0.042
M25.77 Osteophyte (Ankle and foot)	0.000	0.958	0.042
M25.84 Other specified joint disorders (Hand)	0.000	0.959	0.041
M25.0 Haemarthrosis	0.000	0.959	0.041
M25.74 Osteophyte (Hand)	0.000	0.960	0.040
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.961	0.039
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.962	0.038
M25.98 Joint disorder, unspecified (Other)	0.000	0.962	0.038
M25.94 Joint disorder, unspecified (Hand)	0.000	0.962	0.038
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.962	0.038
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.962	0.038
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.962	0.038
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.962	0.038
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.962	0.038
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.963	0.037
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.963	0.037
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.963	0.037
K90-K93 Other diseases of the digestive system	0.000	0.963	0.037
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.964	0.036
M25.79 Osteophyte (Site unspecified)	0.000	0.964	0.036
M25.73 Osteophyte (Forearm)	0.000	0.964	0.036
M25.70 Osteophyte (Multiple sites)	0.000	0.964	0.036
M25.3 Other instability of joint	0.000	0.964	0.036
M25.72 Osteophyte (Upper arm)	0.000	0.964	0.036
M25.86 Other specified joint disorders (Lower leg)	0.000	0.964	0.036
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.965	0.035
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.966	0.034
M25.4 Effusion of joint	0.000	0.968	0.032
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.968	0.032
M25.82 Other specified joint disorders (Upper arm)	0.000	0.968	0.032
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.968	0.032
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.969	0.031
M25.19 Fistula of joint (Site unspecified)	0.000	0.969	0.031
M25.18 Fistula of joint (Other)	0.000	0.969	0.031
M25.17 Fistula of joint (Ankle and foot)	0.000	0.969	0.031
M25.16 Fistula of joint (Lower leg)	0.000	0.969	0.031
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.969	0.031
M25.14 Fistula of joint (Hand)	0.000	0.969	0.031
M25.13 Fistula of joint (Forearm)	0.000	0.969	0.031
M25.12 Fistula of joint (Upper arm)	0.000	0.969	0.031
M25.11 Fistula of joint (Shoulder region)	0.000	0.969	0.031
M25.10 Fistula of joint (Multiple sites)	0.000	0.969	0.031
M25.29 Flail joint (Site unspecified)	0.000	0.969	0.031
M25.28 Flail joint (Other)	0.000	0.969	0.031
M25.27 Flail joint (Ankle and foot)	0.000	0.969	0.031
M25.26 Flail joint (Lower leg)	0.000	0.969	0.031
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.969	0.031
M25.24 Flail joint (Hand)	0.000	0.969	0.031
M25.23 Flail joint (Forearm)	0.000	0.969	0.031
M25.22 Flail joint (Upper arm)	0.000	0.969	0.031
M25.21 Flail joint (Shoulder region)	0.000	0.969	0.031
M25.20 Flail joint (Multiple sites)	0.000	0.969	0.031
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.969	0.031
D70 Agranulocytosis	0.000	0.969	0.031
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.970	0.030
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.970	0.030
D75 Other diseases of blood and blood-forming organs	0.000	0.970	0.030
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.970	0.030
M25.09 Haemarthrosis (Site unspecified)	0.000	0.970	0.029
M25.08 Haemarthrosis (Other)	0.000	0.970	0.029
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.970	0.029
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.970	0.029
M25.04 Haemarthrosis (Hand)	0.000	0.970	0.029
M25.03 Haemarthrosis (Forearm)	0.000	0.970	0.029
M25.02 Haemarthrosis (Upper arm)	0.000	0.970	0.029
M25.01 Haemarthrosis (Shoulder region)	0.000	0.970	0.029
M25.00 Haemarthrosis (Multiple sites)	0.000	0.970	0.029
M25.83 Other specified joint disorders (Forearm)	0.000	0.972	0.028
E00-E07 Disorders of thyroid gland	0.025	0.972	0.003
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.972	0.028
M25.46 Effusion of joint (Lower leg)	0.000	0.972	0.028
M25.37 Other instability of joint (Ankle and foot)	0.000	0.972	0.028
M25.06 Haemarthrosis (Lower leg)	0.000	0.972	0.027
D72 Other disorders of white blood cells	0.000	0.973	0.027
D73 Diseases of spleen	0.000	0.973	0.027
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.973	0.027
M25.36 Other instability of joint (Lower leg)	0.000	0.973	0.026
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.974	0.026
D75.2 Essential thrombocytosis	0.000	0.974	0.026
M25.39 Other instability of joint (Site unspecified)	0.000	0.974	0.026
M25.38 Other instability of joint (Other)	0.000	0.974	0.026
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.974	0.026
M25.32 Other instability of joint (Upper arm)	0.000	0.974	0.026
M25.30 Other instability of joint (Multiple sites)	0.000	0.974	0.026
D72.8 Other specified disorders of white blood cells	0.000	0.974	0.026
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.974	0.026
M25.88 Other specified joint disorders (Other)	0.000	0.974	0.025
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.974	0.025
D73.0 Hyposplenism	0.000	0.974	0.025
M25.43 Effusion of joint (Forearm)	0.000	0.975	0.025
M25.31 Other instability of joint (Shoulder region)	0.000	0.976	0.024
M25.34 Other instability of joint (Hand)	0.000	0.977	0.023
M25.49 Effusion of joint (Site unspecified)	0.000	0.977	0.023
M25.48 Effusion of joint (Other)	0.000	0.977	0.023
M25.41 Effusion of joint (Shoulder region)	0.000	0.977	0.023
M25.33 Other instability of joint (Forearm)	0.000	0.977	0.023
D75.1 Secondary polycythaemia	0.000	0.977	0.023
D74 Methaemoglobinaemia	0.000	0.978	0.022
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.978	0.022
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.978	0.022
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.978	0.022
E07 Other disorders of thyroid	0.020	0.978	0.002
D12.8 Rectum	0.021	0.979	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.979	0.021
M25.42 Effusion of joint (Upper arm)	0.000	0.979	0.020
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.018	0.980	0.002
E00 Congenital iodine-deficiency syndrome	0.018	0.980	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.018	0.980	0.002
D75.0 Familial erythrocytosis	0.000	0.980	0.020
M25.44 Effusion of joint (Hand)	0.000	0.980	0.020
M25.40 Effusion of joint (Multiple sites)	0.000	0.980	0.020
D72.9 Disorder of white blood cells, unspecified	0.000	0.980	0.020
D72.0 Genetic anomalies of leukocytes	0.000	0.980	0.020
D73.9 Disease of spleen, unspecified	0.000	0.980	0.020
D73.8 Other diseases of spleen	0.000	0.980	0.020
D73.4 Cyst of spleen	0.000	0.980	0.020
D73.3 Abscess of spleen	0.000	0.980	0.020
D73.2 Chronic congestive splenomegaly	0.000	0.980	0.020
D73.1 Hypersplenism	0.000	0.980	0.020
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.980	0.019
K93.1 Megacolon in Chagas' disease	0.000	0.980	0.019
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.980	0.019
M25.78 Osteophyte (Other)	0.000	0.981	0.019
E07.9 Disorder of thyroid, unspecified	0.018	0.982	0.000
D73.5 Infarction of spleen	0.000	0.983	0.017
S64.4 Injury of digital nerve of other finger	0.017	0.983	0.000
D72.1 Eosinophilia	0.000	0.984	0.016
D74.9 Methaemoglobinaemia, unspecified	0.000	0.984	0.016
D74.8 Other methaemoglobinaemias	0.000	0.984	0.016
D74.0 Congenital methaemoglobinaemia	0.000	0.984	0.016
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.984	0.016
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.984	0.016
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.984	0.016
D76.3 Other histiocytosis syndromes	0.000	0.984	0.016
E07.1 Dyshormogenetic goitre	0.015	0.984	0.001
E07.0 Hypersecretion of calcitonin	0.015	0.984	0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.013	0.985	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.013	0.985	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.013	0.985	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.013	0.985	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.013	0.985	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.013	0.985	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.013	0.985	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.013	0.985	0.002
E07.8 Other specified disorders of thyroid	0.013	0.986	0.001
M25.47 Effusion of joint (Ankle and foot)	0.000	0.986	0.014
E06 Thyroiditis	0.010	0.987	0.003
I47.2 Ventricular tachycardia	0.013	0.987	0.000
R47.0 Dysphasia and aphasia	0.000	0.987	0.013
E66.8 Other obesity	0.000	0.987	0.013
I47 Paroxysmal tachycardia	0.012	0.988	0.000
R94.3 Abnormal results of cardiovascular function studies	0.012	0.988	0.000
I47.1 Supraventricular tachycardia	0.012	0.988	0.000
S64 Injury of nerves at wrist and hand level	0.012	0.988	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.012	0.988	0.000
D86 Sarcoidosis	0.000	0.989	0.011
S61.0 Open wound of finger(s) without damage to nail	0.011	0.989	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.990	0.010
S61.8 Open wound of other parts of wrist and hand	0.010	0.990	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.990	0.010
D86.8 Sarcoidosis of other and combined sites	0.000	0.990	0.010
D86.0 Sarcoidosis of lung	0.000	0.990	0.010
D80-D89 Certain disorders involving the immune mechanism	0.000	0.990	0.010
D12.5 Sigmoid colon	0.010	0.990	0.000
E66 Obesity	0.000	0.990	0.010
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.990	0.010
S61 Open wound of wrist and hand	0.010	0.990	0.000
S60-S69 Injuries to the wrist and hand	0.010	0.990	0.000
C71.9 Brain, unspecified	0.010	0.990	0.000
I47.0 Reentry ventricular arrhythmia	0.010	0.990	0.000
E06.5 Other chronic thyroiditis	0.007	0.990	0.002
E06.4 Drug-induced thyroiditis	0.007	0.990	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.007	0.990	0.002
E06.1 Subacute thyroiditis	0.007	0.990	0.002
E06.0 Acute thyroiditis	0.007	0.990	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.009	0.990	0.000
S60.8 Other superficial injuries of wrist and hand	0.009	0.990	0.000
C18.7 Sigmoid colon	0.009	0.991	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.009	0.991	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.991	0.009
E66.0 Obesity due to excess calories	0.000	0.991	0.009
S64.2 Injury of radial nerve at wrist and hand level	0.009	0.991	0.000
S60 Superficial injury of wrist and hand	0.009	0.991	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.991	0.009
S64.1 Injury of median nerve at wrist and hand level	0.009	0.991	0.000
C71.0 Cerebrum, except lobes and ventricles	0.009	0.991	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.009	0.991	0.000
S64.8 Injury of other nerves at wrist and hand level	0.009	0.991	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.009	0.991	0.000
D12.7 Rectosigmoid junction	0.009	0.991	0.000
D12.4 Descending colon	0.009	0.991	0.000
D86.3 Sarcoidosis of skin	0.000	0.991	0.009
C71 Malignant neoplasm of brain	0.009	0.991	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.991	0.008
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.991	0.008
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.992	0.008
S68 Traumatic amputation of wrist and hand	0.008	0.992	0.000
M20-M25 Other joint disorders	0.000	0.992	0.008
S60.9 Superficial injury of wrist and hand, unspecified	0.008	0.992	0.000
C71.2 Temporal lobe	0.008	0.992	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.992	0.008
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.992	0.004
D50-D53 Nutritional anaemias	0.000	0.992	0.008
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.992	0.008
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.992	0.007
S62 Fracture at wrist and hand level	0.008	0.992	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.993	0.007
D82 Immunodeficiency associated with other major defects	0.000	0.993	0.007
D81 Combined immunodeficiencies	0.000	0.993	0.007
E66.1 Drug-induced obesity	0.000	0.993	0.007
K91.1 Postgastric surgery syndromes	0.000	0.993	0.007
E06.9 Thyroiditis, unspecified	0.004	0.993	0.003
K91.5 Postcholecystectomy syndrome	0.000	0.993	0.007
S68.0 Traumatic amputation of thumb (complete)(partial)	0.007	0.993	0.000
M21 Other acquired deformities of limbs	0.000	0.993	0.007
D83 Common variable immunodeficiency	0.000	0.993	0.007
E06.3 Autoimmune thyroiditis	0.005	0.993	0.002
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.007	0.993	0.000
D41.4 Bladder	0.007	0.993	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.007	0.993	0.000
S60.1 Contusion of finger(s) with damage to nail	0.007	0.993	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.007	0.993	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.993	0.007
J98.4 Other disorders of lung	0.007	0.993	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.007	0.993	0.000
D55-D59 Haemolytic anaemias	0.000	0.993	0.007
D84 Other immunodeficiencies	0.000	0.993	0.007
M24 Other specific joint derangements	0.000	0.993	0.007
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.993	0.007
E65-E68 Obesity and other hyperalimentation	0.000	0.993	0.007
S65 Injury of blood vessels at wrist and hand level	0.007	0.993	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.993	0.007
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.993	0.006
D53 Other nutritional anaemias	0.000	0.993	0.007
M24.0 Loose body in joint	0.000	0.993	0.007
M32 Systemic lupus erythematosus	0.000	0.993	0.006
C71.7 Brain stem	0.006	0.993	0.000
C71.6 Cerebellum	0.006	0.993	0.000
C71.5 Cerebral ventricle	0.006	0.993	0.000
C71.4 Occipital lobe	0.006	0.993	0.000
C71.3 Parietal lobe	0.006	0.993	0.000
M31 Other necrotising vasculopathies	0.000	0.993	0.006
D12.9 Anus and anal canal	0.006	0.994	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.994	0.006
S62.7 Multiple fractures of fingers	0.006	0.994	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.994	0.006
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.006	0.994	0.000
M34 Systemic sclerosis	0.000	0.994	0.006
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.006	0.994	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.006	0.994	0.000
S67 Crushing injury of wrist and hand	0.006	0.994	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.006	0.994	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.994	0.006
M30 Polyarteritis nodosa and related conditions	0.000	0.994	0.006
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.994	0.006
M24.1 Other articular cartilage disorders	0.000	0.994	0.006
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.006	0.994	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.006	0.994	0.000
S68.4 Traumatic amputation of hand at wrist level	0.006	0.994	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.006	0.994	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.994	0.006
S62.5 Fracture of thumb	0.006	0.994	0.000
E04 Other non-toxic goitre	0.005	0.994	0.001
C77.2 Intra-abdominal lymph nodes	0.006	0.994	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.994	0.006
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.994	0.006
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.994	0.006
D12.2 Ascending colon	0.006	0.994	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.994	0.006
M24.01 Loose body in joint (Shoulder region)	0.000	0.994	0.006
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.994	0.006
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.994	0.006
D51.2 Transcobalamin II deficiency	0.000	0.994	0.006
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.994	0.006
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.006	0.994	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.994	0.006
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.994	0.006
E05.8 Other thyrotoxicosis	0.002	0.994	0.003
E05.5 Thyroid crisis or storm	0.002	0.994	0.003
E05.4 Thyrotoxicosis factitia	0.002	0.994	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.994	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.994	0.003
S60.2 Contusion of other parts of wrist and hand	0.006	0.994	0.000
S60.0 Contusion of finger(s) without damage to nail	0.006	0.994	0.000
S62.70 Multiple fractures of fingers (closed)	0.006	0.994	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.994	0.006
E65 Localised adiposity	0.000	0.994	0.006
C18 Malignant neoplasm of colon	0.006	0.994	0.000
M31.6 Other giant cell arteritis	0.000	0.994	0.006
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.994	0.005
D89.3 Immune reconstitution syndrome	0.000	0.994	0.005
D89.1 Cryoglobulinaemia	0.000	0.994	0.005
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.994	0.005
S62.1 Fracture of other carpal bone(s)	0.006	0.994	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.006	0.994	0.000
M33 Dermatopolymyositis	0.000	0.994	0.006
S62.4 Multiple fractures of metacarpal bones	0.006	0.994	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.994	0.005
D81.8 Other combined immunodeficiencies	0.000	0.994	0.005
D81.7 Major histocompatibility complex class II deficiency	0.000	0.994	0.005
D81.6 Major histocompatibility complex class I deficiency	0.000	0.994	0.005
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.994	0.005
D81.4 Nezelof's syndrome	0.000	0.994	0.005
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.994	0.005
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.994	0.005
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.994	0.005
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.994	0.005
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.994	0.005
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.994	0.005
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.994	0.005
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.994	0.005
D82.2 Immunodeficiency with short-limbed stature	0.000	0.994	0.005
D82.1 Di George's syndrome	0.000	0.994	0.005
D82.0 Wiskott-Aldrich syndrome	0.000	0.994	0.005
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.994	0.005
M21.4 Flat foot [pes planus] (acquired)	0.000	0.994	0.005
D12.1 Appendix	0.005	0.994	0.000
C71.8 Overlapping lesion of brain	0.005	0.994	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.994	0.005
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.995	0.004
M21.9 Acquired deformity of limb, unspecified	0.000	0.995	0.005
M21.8 Other specified acquired deformities of limbs	0.000	0.995	0.005
M21.7 Unequal limb length (acquired)	0.000	0.995	0.005
S63.5 Sprain and strain of wrist	0.005	0.995	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.005	0.995	0.000
C71.1 Frontal lobe	0.005	0.995	0.000
F43.1 Posttraumatic stress disorder	0.005	0.995	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.995	0.005
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.995	0.005
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.995	0.005
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.995	0.005
S63.0 Dislocation of wrist	0.005	0.995	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.005	0.995	0.000
S63.1 Dislocation finger	0.005	0.995	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.005	0.995	0.000
S63.2 Multiple dislocations of fingers	0.005	0.995	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.005	0.995	0.000
S64.3 Injury of digital nerve of thumb	0.005	0.995	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.995	0.005
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.995	0.005
E11.4 With neurological complications	0.000	0.995	0.005
K91.4 Colostomy and enterostomy malfunction	0.000	0.995	0.005
M34.9 Systemic sclerosis, unspecified	0.000	0.995	0.005
S69 Other and unspecified injuries of wrist and hand	0.005	0.995	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.995	0.005
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.005	0.995	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.995	0.005
S62.3 Fracture of other metacarpal bone	0.005	0.995	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.005	0.995	0.000
S62.2 Fracture of first metacarpal bone	0.005	0.995	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.005	0.995	0.000
D57 Sickle-cell disorders	0.000	0.995	0.005
D55 Anaemia due to enzyme disorders	0.000	0.995	0.005
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.995	0.005
C18.1 Appendix	0.005	0.995	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.995	0.005
D84.8 Other specified immunodeficiencies	0.000	0.995	0.005
D84.1 Defects in the complement system	0.000	0.995	0.005
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.995	0.005
M24.9 Joint derangement, unspecified	0.000	0.995	0.005
M24.6 Ankylosis of joint	0.000	0.995	0.005
S62.0 Fracture of navicular [scaphoid] bone of hand	0.005	0.995	0.000
S65.1 Injury of radial artery at wrist and hand level	0.005	0.995	0.000
S62.50 Fracture of thumb (closed)	0.005	0.995	0.000
C18.0 Caecum	0.005	0.995	0.000
M21.6 Other acquired deformities of ankle and foot	0.000	0.995	0.005
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.005	0.995	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.005	0.995	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.005	0.995	0.000
S65.4 Injury of blood vessel(s) of thumb	0.005	0.995	0.000
S65.3 Injury of deep palmar arch	0.005	0.995	0.000
S65.2 Injury of superficial palmar arch	0.005	0.995	0.000
E67 Other hyperalimentation	0.000	0.995	0.005
E68 Sequelae of hyperalimentation	0.000	0.995	0.005
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.995	0.005
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.995	0.005
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.995	0.005
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.995	0.005
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.995	0.005
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.995	0.005
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.995	0.005
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.995	0.005
D83.9 Common variable immunodeficiency, unspecified	0.000	0.995	0.005
I42.8 Other cardiomyopathies	0.005	0.995	0.000
D56 Thalassaemia	0.000	0.995	0.005
M34.8 Other forms of systemic sclerosis	0.000	0.995	0.005
S65.5 Injury of blood vessel(s) of other finger	0.005	0.995	0.000
D53.8 Other specified nutritional anaemias	0.000	0.995	0.005
D53.2 Scorbutic anaemia	0.000	0.995	0.005
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.995	0.005
D53.0 Protein deficiency anaemia	0.000	0.995	0.005
S61.7 Multiple open wounds of wrist and hand	0.005	0.995	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.995	0.005
D58 Other hereditary haemolytic anaemias	0.000	0.995	0.005
M24.09 Loose body in joint (Site unspecified)	0.000	0.995	0.005
M24.08 Loose body in joint (Other)	0.000	0.995	0.005
M24.06 Loose body in joint-Lower leg	0.000	0.995	0.005
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.995	0.005
M24.04 Loose body in joint (Hand)	0.000	0.995	0.005
M24.03 Loose body in joint (Forearm)	0.000	0.995	0.005
M24.00 Loose body in joint (Multiple sites)	0.000	0.995	0.005
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.995	0.005
M32.8 Other forms of systemic lupus erythematosus	0.000	0.995	0.005
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.995	0.005
M31.8 Other specified necrotising vasculopathies	0.000	0.995	0.005
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.995	0.005
M31.2 Lethal midline granuloma	0.000	0.995	0.005
M31.1 Thrombotic microangiopathy	0.000	0.995	0.005
M31.0 Hypersensitivity angiitis	0.000	0.995	0.005
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.995	0.005
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.995	0.005
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.995	0.005
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.995	0.005
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.995	0.005
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.995	0.005
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.995	0.005
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.995	0.005
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.995	0.005
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.995	0.005
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.005	0.995	0.000
D59 Acquired haemolytic anaemia	0.000	0.995	0.005
C18.6 Descending colon	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations