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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7759666
log Bayes Factor = 11.2061
Chromosome 6   position 30,569,489  (GRCh37) Explore rs7759666 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10.9 Without complications
0.000 0.163 0.837
E10 Insulin-dependent diabetes mellitus
0.000 0.183 0.817
E10.1 With ketoacidosis
0.000 0.235 0.765
E10.3 With ophthalmic complications
0.000 0.262 0.738
E10.4 With neurological complications
0.000 0.298 0.702
E10.2 With renal complications
0.000 0.344 0.656
E10.5 With peripheral circulatory complications
0.000 0.376 0.624
E10.8 With unspecified complications
0.000 0.414 0.586
E10.7 With multiple complications
0.000 0.414 0.586
E10.6 With other specified complications
0.000 0.414 0.586
E10.0 With coma
0.000 0.414 0.586
K90 Intestinal malabsorption
0.000 0.801 0.198
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.833 0.167
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.836 0.164
C85.1 B-cell lymphoma, unspecified
0.000 0.845 0.155
E10-E14 Diabetes mellitus
0.000 0.848 0.152
K90.3 Pancreatic steatorrhoea
0.000 0.857 0.142
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.857 0.142
K90.1 Tropical sprue
0.000 0.857 0.142
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.862 0.138
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.862 0.138
C83.3 Large cell (diffuse)
0.000 0.866 0.134
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.868 0.132
K90.8 Other intestinal malabsorption
0.000 0.868 0.132
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.868 0.131
C83.0 Small cell (diffuse)
0.000 0.878 0.122
E13 Other specified diabetes mellitus
0.000 0.879 0.121
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.882 0.117
C85.0 Lymphosarcoma
0.000 0.882 0.117
C83.1 Small cleaved cell (diffuse)
0.000 0.884 0.116
C88 Malignant immunoproliferative diseases
0.000 0.886 0.114
E12 Malnutrition-related diabetes mellitus
0.000 0.891 0.109
C92 Myeloid leukaemia
0.000 0.893 0.107
C91 Lymphoid leukaemia
0.000 0.895 0.105
E13.9 Without complications
0.000 0.901 0.099
C93 Monocytic leukaemia
0.000 0.901 0.099
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.901 0.099
C95 Leukaemia of unspecified cell type
0.000 0.901 0.099
C94 Other leukaemias of specified cell type
0.000 0.901 0.099
C86 Other specified types of T/NK-cell lymphoma
0.000 0.901 0.099
C83.6 Undifferentiated (diffuse)
0.000 0.901 0.099
C83.5 Lymphoblastic (diffuse)
0.000 0.901 0.099
C83.4 Immunoblastic (diffuse)
0.000 0.901 0.099
C83.2 Mixed small and large cell (diffuse)
0.000 0.901 0.099
C83.7 Burkitt's tumour
0.000 0.902 0.098
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.902 0.097
C91.1 Chronic lymphocytic leukaemia
0.000 0.906 0.094
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.906 0.094
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.909 0.091
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.909 0.091
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.911 0.089
E13.8 With unspecified complications
0.000 0.913 0.087
E13.7 With multiple complications
0.000 0.913 0.087
E13.6 With other specified complications
0.000 0.913 0.087
E13.5 With peripheral circulatory complications
0.000 0.913 0.087
E13.4 With neurological complications
0.000 0.913 0.087
E13.3 With ophthalmic complications
0.000 0.913 0.087
E13.2 With renal complications
0.000 0.913 0.087
E13.1 With ketoacidosis
0.000 0.913 0.087
E13.0 With coma
0.000 0.913 0.087
E14 Unspecified diabetes mellitus
0.000 0.913 0.087
C92.0 Acute myeloid leukaemia
0.000 0.914 0.086
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.918 0.082
C88.7 Other malignant immunoproliferative diseases
0.000 0.918 0.082
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.918 0.082
C88.3 Immunoproliferative small intestinal disease
0.000 0.918 0.082
C88.2 Gamma heavy chain disease
0.000 0.918 0.082
C88.1 Alpha heavy chain disease
0.000 0.918 0.082
C92.1 Chronic myeloid leukaemia
0.000 0.919 0.081
E12.9 Without complications
0.000 0.922 0.078
E12.8 With unspecified complications
0.000 0.922 0.078
E12.7 With multiple complications
0.000 0.922 0.078
E12.6 With other specified complications
0.000 0.922 0.078
E12.5 With peripheral circulatory complications
0.000 0.922 0.078
E12.4 With neurological complications
0.000 0.922 0.078
E12.3 With ophthalmic complications
0.000 0.922 0.078
E12.2 With renal complications
0.000 0.922 0.078
E12.1 With ketoacidosis
0.000 0.922 0.078
E12.0 With coma
0.000 0.922 0.078
C92.9 Myeloid leukaemia, unspecified
0.000 0.923 0.077
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.923 0.077
C92.7 Other myeloid leukaemia
0.000 0.923 0.077
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.923 0.077
C92.5 Acute myelomonocytic leukaemia
0.000 0.923 0.077
C92.3 Myeloid sarcoma
0.000 0.923 0.077
C92.2 Subacute myeloid leukaemia
0.000 0.923 0.077
C91.9 Lymphoid leukaemia, unspecified
0.000 0.924 0.076
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.924 0.075
C91.7 Other lymphoid leukaemia
0.000 0.924 0.075
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.924 0.075
C91.3 Prolymphocytic leukaemia
0.000 0.924 0.075
C91.2 Subacute lymphocytic leukaemia
0.000 0.924 0.075
C90.2 Plasmacytoma, extramedullary
0.000 0.927 0.073
C91.4 Hairy-cell leukaemia
0.000 0.927 0.072
C93.1 Chronic monocytic leukaemia
0.000 0.928 0.072
C93.9 Monocytic leukaemia, unspecified
0.000 0.928 0.071
C93.7 Other monocytic leukaemia
0.000 0.928 0.071
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.928 0.071
C93.2 Subacute monocytic leukaemia
0.000 0.928 0.071
C93.0 Acute monocytic leukaemia
0.000 0.928 0.071
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.929 0.071
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.929 0.071
C86.4 Blastic NK-cell lymphoma
0.000 0.929 0.071
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.929 0.071
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.929 0.071
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.929 0.071
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.929 0.071
C94.7 Other specified leukaemias
0.000 0.929 0.071
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.929 0.071
C94.5 Acute myelofibrosis
0.000 0.929 0.071
C94.4 Acute panmyelosis
0.000 0.929 0.071
C94.3 Mast cell leukaemia
0.000 0.929 0.071
C94.2 Acute megakaryoblastic leukaemia
0.000 0.929 0.071
C94.1 Chronic erythraemia
0.000 0.929 0.071
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.929 0.071
C95.9 Leukaemia, unspecified
0.000 0.929 0.071
C95.7 Other leukaemia of unspecified cell type
0.000 0.929 0.071
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.929 0.071
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.929 0.071
C95.0 Acute leukaemia of unspecified cell type
0.000 0.929 0.071
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.929 0.071
C96.8 Histiocytic sarcoma
0.000 0.929 0.071
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.929 0.071
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.929 0.071
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.929 0.071
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.929 0.071
C96.3 True histiocytic lymphoma
0.000 0.929 0.071
C96.2 Malignant mast cell tumour
0.000 0.929 0.071
C96.1 Malignant histiocytosis
0.000 0.929 0.071
C96.0 Letterer-Siwe disease
0.000 0.929 0.071
E14.3 With ophthalmic complications
0.000 0.929 0.071
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.929 0.071
K90.9 Intestinal malabsorption, unspecified
0.001 0.930 0.070
C92.4 Acute promyelocytic leukaemia
0.000 0.930 0.070
C90.3 Solitary plasmacytoma
0.000 0.932 0.068
C84.5 Other and unspecified T-cell lymphomas
0.000 0.933 0.066
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.934 0.065
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.934 0.065
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.934 0.065
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.934 0.065
C84.3 Lymphoepithelioid lymphoma
0.000 0.934 0.065
C84.2 T-zone lymphoma
0.000 0.934 0.065
C84.1 Sezary's diease
0.000 0.934 0.065
C91.0 Acute lymphoblastic leukaemia
0.000 0.935 0.065
C84.0 Mycosis fungoides
0.000 0.937 0.063
E14.4 With neurological complications
0.000 0.937 0.063
C90.1 Plasma cell leukaemia
0.000 0.937 0.063
E14.7 With multiple complications
0.000 0.937 0.063
E14.6 With other specified complications
0.000 0.937 0.063
E14.5 With peripheral circulatory complications
0.000 0.937 0.063
E14.2 Withrenal complications
0.000 0.937 0.063
E14.0 With coma
0.000 0.937 0.063
C90.0 Multiple myeloma
0.000 0.938 0.062
C91.5 Adult T-cell leukaemia
0.000 0.939 0.061
E14.8 With unspecified complications
0.000 0.940 0.060
E14.1 With ketoacidosis
0.000 0.941 0.059
C84.4 Peripheral T-cell lymphoma
0.000 0.941 0.059
C81 Hodgkin's disease
0.001 0.946 0.054
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.946 0.053
R31 Unspecified haematuria
0.054 0.946 0.000
C82.6 Cutaneous follicle centre lymphoma
0.000 0.949 0.051
C82.5 Diffuse follicle centre lymphoma
0.000 0.949 0.051
C82.4 Follicular lymphoma grade IIIb
0.000 0.949 0.051
C82.3 Follicular lymphoma grade IIIa
0.000 0.949 0.051
E05.9 Thyrotoxicosis, unspecified
0.000 0.949 0.051
C82.0 Small cleaved cell, follicular
0.000 0.949 0.050
C82.2 Large cell, follicular
0.000 0.952 0.048
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.955 0.045
C81.7 Other Hodgkin's disease
0.001 0.961 0.039
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.001 0.961 0.039
C81.3 Lymphocytic depletion
0.001 0.961 0.039
C81.2 Mixed cellularity
0.001 0.961 0.039
C81.0 Lymphocytic predominance
0.000 0.962 0.038
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.963 0.037
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.966 0.034
E14.9 Without complications
0.000 0.969 0.031
C81.1 Nodular sclerosis
0.001 0.970 0.029
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.971 0.029
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.973 0.027
E05.8 Other thyrotoxicosis
0.000 0.973 0.027
E05.5 Thyroid crisis or storm
0.000 0.974 0.026
E05.4 Thyrotoxicosis factitia
0.000 0.974 0.026
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.974 0.026
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.978 0.022
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.978 0.022
E00-E07 Disorders of thyroid gland
0.000 0.979 0.021
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.981 0.019
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.019 0.981 0.000
C81.9 Hodgkin's disease, unspecified
0.001 0.981 0.018
E16 Other disorders of pancreatic internal secretion
0.000 0.983 0.017
D50.9 Iron deficiency anaemia, unspecified
0.000 0.983 0.017
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.984 0.016
E16.2 Hypoglycaemia, unspecified
0.000 0.984 0.016
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.985 0.015
E00 Congenital iodine-deficiency syndrome
0.000 0.985 0.015
E40-E46 Malnutrition
0.000 0.985 0.015
E15 Nondiabetic hypoglycaemic coma
0.000 0.986 0.014
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.986 0.014
E07 Other disorders of thyroid
0.000 0.987 0.013
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.987 0.013
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.987 0.012
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.987 0.012
E16.4 Abnormal secretion of gastrin
0.000 0.987 0.012
E16.3 Increased secretion of glucagon
0.000 0.987 0.012
E16.1 Other hypoglycaemia
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.988 0.012
K93.1 Megacolon in Chagas' disease
0.000 0.988 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.988 0.012
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.012 0.988 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.989 0.011
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.989 0.011
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.989 0.011
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.989 0.011
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.989 0.011
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.989 0.011
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.989 0.011
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.989 0.011
E06 Thyroiditis
0.000 0.989 0.011
T36-T50 Poisoning by drugs, medicaments and biological substances
0.011 0.989 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.989 0.011
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.989 0.011
E45 Retarded development following protein-energy malnutrition
0.000 0.989 0.011
E43 Unspecified severe protein-energy malnutrition
0.000 0.989 0.011
E42 Marasmic kwashiorkor
0.000 0.989 0.011
E41 Nutritional marasmus
0.000 0.989 0.011
E40 Kwashiorkor
0.000 0.989 0.011
E65-E68 Obesity and other hyperalimentation
0.000 0.989 0.011
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.010 0.990 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.010 0.990 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.990 0.010
E50-E64 Other nutritional deficiencies
0.000 0.990 0.010
T42.1 Iminostilbenes
0.010 0.990 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.010 0.990 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.010 0.990 0.000
E07.8 Other specified disorders of thyroid
0.000 0.990 0.010
E07.1 Dyshormogenetic goitre
0.000 0.990 0.010
E07.0 Hypersecretion of calcitonin
0.000 0.990 0.010
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.990 0.010
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.010 0.990 0.000
K91.3 Postoperative intestinal obstruction
0.000 0.991 0.009
T45.0 Antiallergic and antiemetic drugs
0.009 0.991 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.009 0.991 0.000
K91.1 Postgastric surgery syndromes
0.000 0.991 0.009
M45.X9 Ankylosing spondylitis (Site unspecified)
0.009 0.991 0.000
T39.4 Antirheumatics, not elsewhere classified
0.009 0.991 0.000
T39.2 Pyrazolone derivatives
0.009 0.991 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.009 0.991 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.009 0.991 0.000
T45.5 Anticoagulants
0.009 0.991 0.000
E65 Localised adiposity
0.000 0.991 0.008
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.008 0.991 0.000
T46.1 Calcium-channel blockers
0.008 0.991 0.000
E06.5 Other chronic thyroiditis
0.000 0.992 0.008
E06.4 Drug-induced thyroiditis
0.000 0.992 0.008
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.992 0.008
E06.1 Subacute thyroiditis
0.000 0.992 0.008
E06.0 Acute thyroiditis
0.000 0.992 0.008
T36 Poisoning by systemic antibiotics
0.008 0.992 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.008 0.992 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.008 0.992 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.008 0.992 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.008 0.992 0.000
R40.2 Coma, unspecified
0.000 0.992 0.008
K91.5 Postcholecystectomy syndrome
0.000 0.992 0.008
E44.1 Mild protein-energy malnutrition
0.000 0.992 0.008
E44.0 Moderate protein-energy malnutrition
0.000 0.992 0.008
T42.0 Hydantoin derivatives
0.008 0.992 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.992 0.008
E27.1 Primary adrenocortical insufficiency
0.000 0.992 0.008
T45.1 Antineoplastic and immunosuppressive drugs
0.008 0.992 0.000
E67 Other hyperalimentation
0.000 0.992 0.008
E68 Sequelae of hyperalimentation
0.000 0.992 0.008
T43.5 Other and unspecified antipsychotics and neuroleptics
0.008 0.992 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.008 0.992 0.000
T43.2 Other and unspecified antidepressants
0.008 0.992 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.008 0.992 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.008 0.992 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.008 0.992 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.008 0.992 0.000
T42.3 Barbiturates
0.008 0.992 0.000
T42.2 Succinimides and oxazolidinediones
0.008 0.992 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.008 0.992 0.000
T45.8 Other primarily systemic and haematological agents
0.008 0.992 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.008 0.992 0.000
T45.6 Fibrinolysis-affecting drugs
0.008 0.992 0.000
T45.4 Iron and its compounds
0.008 0.992 0.000
T45.3 Enzymes, not elsewhere classified
0.008 0.992 0.000
T45.2 Vitamins, not elsewhere classified
0.008 0.992 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.008 0.992 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.008 0.992 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.992 0.008
E03 Other hypothyroidism
0.000 0.992 0.008
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.992 0.007
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.007 0.992 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.993 0.007
E63 Other nutritional deficiencies
0.000 0.993 0.007
E56 Other vitamin deficiencies
0.000 0.993 0.007
E50 Vitamin A deficiency
0.000 0.993 0.007
E60 Dietary zinc deficiency
0.000 0.993 0.007
E59 Dietary selenium deficiency
0.000 0.993 0.007
E58 Dietary calcium deficiency
0.000 0.993 0.007
E54 Ascorbic acid deficiency
0.000 0.993 0.007
E52 Niacin deficiency [pellagra]
0.000 0.993 0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.007 0.993 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.007 0.993 0.000
T46.7 Peripheral vasodilators
0.007 0.993 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.007 0.993 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.007 0.993 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.993 0.007
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.993 0.007
T43.4 Butyrophenone and thioxanthene neuroleptics
0.007 0.993 0.000
D50 Iron deficiency anaemia
0.000 0.993 0.007
E27 Other disorders of adrenal gland
0.000 0.993 0.007
E51 Thiamine deficiency
0.000 0.993 0.007
E53 Deficiency of other B group vitamins
0.000 0.993 0.007
E20 Hypoparathyroidism
0.000 0.993 0.007
T43.9 Psychotropic drug, unspecified
0.007 0.993 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.007 0.993 0.000
T43.6 Psychostimulants with abuse potential
0.007 0.993 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.007 0.993 0.000
E06.9 Thyroiditis, unspecified
0.000 0.993 0.007
T43.3 Phenothiazine antipsychotics and neuroleptics
0.007 0.993 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.993 0.007
T46.4 Angiotensin-converting-enzyme inhibitors
0.007 0.993 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.006 0.993 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.007 0.993 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.007 0.993 0.000
N10 Acute tubulo-interstitial nephritis
0.007 0.993 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.006 0.993 0.000
E04 Other non-toxic goitre
0.000 0.993 0.007
T40.5 Cocaine
0.006 0.993 0.000
E28 Ovarian dysfunction
0.000 0.993 0.006
E06.3 Autoimmune thyroiditis
0.000 0.993 0.006
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.006 0.993 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.006 0.994 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.006 0.994 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.006 0.994 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.006 0.994 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.006 0.994 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.006 0.994 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.006 0.994 0.000
T44.0 Anticholinesterase agents
0.006 0.994 0.000
T50.8 Diagnostic agents
0.006 0.994 0.000
T50.7 Analeptics and opioid receptor antagonists
0.006 0.994 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.006 0.994 0.000
T50.5 Appetite depressants
0.006 0.994 0.000
T50.4 Drugs affecting uric acid metabolism
0.006 0.994 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.006 0.994 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.006 0.994 0.000
T50.1 Loop [high-ceiling] diuretics
0.006 0.994 0.000
T50.0 Mineralocorticoids and their antagonists
0.006 0.994 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.006 0.994 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.006 0.994 0.000
T47.7 Emetics
0.006 0.994 0.000
T47.6 Antidiarrhoeal drugs
0.006 0.994 0.000
T47.5 Digestants
0.006 0.994 0.000
T47.4 Other laxatives
0.006 0.994 0.000
T47.3 Saline and osmotic laxatives
0.006 0.994 0.000
T47.2 Stimulant laxatives
0.006 0.994 0.000
T47.0 Histamine H(2)-receptor antagonists
0.006 0.994 0.000
M45 Ankylosing spondylitis
0.006 0.994 0.000
T40.6 Other and unspecified narcotics
0.006 0.994 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.994 0.006
T36.9 Systemic antibiotic, unspecified
0.006 0.994 0.000
T36.8 Other systemic antibiotics
0.006 0.994 0.000
T36.7 Antifungal antibiotics, systemically used
0.006 0.994 0.000
T36.6 Rifamycins
0.006 0.994 0.000
T36.5 Aminoglycosides
0.006 0.994 0.000
T36.4 Tetracyclines
0.006 0.994 0.000
T36.3 Macrolides
0.006 0.994 0.000
T36.2 Chloramphenicol group
0.006 0.994 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.006 0.994 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.006 0.994 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.006 0.994 0.000
T37.5 Antiviral drugs
0.006 0.994 0.000
T37.4 Anthelminthics
0.006 0.994 0.000
T37.3 Other antiprotozoal drugs
0.006 0.994 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.006 0.994 0.000
T37.1 Antimycobacterial drugs
0.006 0.994 0.000
T37.0 Sulphonamides
0.006 0.994 0.000
T41.5 Therapeutic gases
0.006 0.994 0.000
T41.4 Anaesthetic, unspecified
0.006 0.994 0.000
T41.3 Local anaesthetics
0.006 0.994 0.000
T41.2 Other and unspecified general anaesthetics
0.006 0.994 0.000
T41.1 Intravenous anaesthetics
0.006 0.994 0.000
T41.0 Inhaled anaesthetics
0.006 0.994 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.006 0.994 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.006 0.994 0.000
T48.5 Anti-common-cold drugs
0.006 0.994 0.000
T48.4 Expectorants
0.006 0.994 0.000
T48.3 Antitussives
0.006 0.994 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.006 0.994 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.006 0.994 0.000
T48.0 Oxytocic drugs
0.006 0.994 0.000
T49.9 Topical agent, unspecified
0.006 0.994 0.000
T49.8 Other topical agents
0.006 0.994 0.000
T49.7 Dental drugs, topically applied
0.006 0.994 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.006 0.994 0.000
T49.5 Ophthalmological drugs and preparations
0.006 0.994 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.006 0.994 0.000
T49.3 Emollients, demulcents and protectants
0.006 0.994 0.000
T49.2 Local astringents and local detergents
0.006 0.994 0.000
T49.1 Antipruritics
0.006 0.994 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.006 0.994 0.000
T36.0 Penicillins
0.006 0.994 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.006 0.994 0.000
K61.0 Anal abscess
0.006 0.994 0.000
E55 Vitamin D deficiency
0.000 0.994 0.006
E29 Testicular dysfunction
0.000 0.994 0.006
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.994 0.006
E34 Other endocrine disorders
0.000 0.994 0.006
E32 Diseases of thymus
0.000 0.994 0.006
E31 Polyglandular dysfunction
0.000 0.994 0.006
E30 Disorders of puberty, not elsewhere classified
0.000 0.994 0.006
E25 Adrenogenital disorders
0.000 0.994 0.006
E20.9 Hypoparathyroidism, unspecified
0.000 0.994 0.006
E67.8 Other specified hyperalimentation
0.000 0.994 0.006
E67.3 Hypervitaminosis D
0.000 0.994 0.006
E67.2 Megavitamin-B6 syndrome
0.000 0.994 0.006
E67.1 Hypercarotenaemia
0.000 0.994 0.006
E67.0 Hypervitaminosis A
0.000 0.994 0.006
E28.2 Polycystic ovarian syndrome
0.000 0.994 0.006
T39.0 Salicylates
0.006 0.994 0.000
E26 Hyperaldosteronism
0.000 0.994 0.006
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.006 0.994 0.000
T40.8 Lysergide [LSD]
0.006 0.994 0.000
T40.7 Cannabis (derivatives)
0.006 0.994 0.000
T40.3 Methadone
0.006 0.994 0.000
T40.1 Heroin
0.006 0.994 0.000
T40.0 Opium
0.006 0.994 0.000
E03.5 Myxoedema coma
0.000 0.994 0.006
E03.4 Atrophy of thyroid (acquired)
0.000 0.994 0.006
E03.3 Postinfectious hypothyroidism
0.000 0.994 0.006
E03.1 Congenital hypothyroidism without goitre
0.000 0.994 0.006
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.994 0.006
E50.9 Vitamin A deficiency, unspecified
0.000 0.994 0.005
E50.8 Other manifestations of vitamin A deficiency
0.000 0.994 0.005
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.994 0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.994 0.005
E50.5 Vitamin A deficiency with night blindness
0.000 0.994 0.005
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.994 0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.994 0.005
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.994 0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.994 0.005
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.994 0.005
E56.9 Vitamin deficiency, unspecified
0.000 0.994 0.005
E56.8 Deficiency of other vitamins
0.000 0.994 0.005
E56.1 Deficiency of vitamin K
0.000 0.994 0.005
E56.0 Deficiency of vitamin E
0.000 0.994 0.005
E63.9 Nutritional deficiency, unspecified
0.000 0.994 0.005
E63.8 Other specified nutritional deficiencies
0.000 0.994 0.005
E63.1 Imbalance of constituents of food intake
0.000 0.994 0.005
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.994 0.005
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.994 0.005
E64.8 Sequelae of other nutritional deficiencies
0.000 0.994 0.005
E64.3 Sequelae of rickets
0.000 0.994 0.005
E64.2 Sequelae of vitamin C deficiency
0.000 0.994 0.005
E64.1 Sequelae of vitamin A deficiency
0.000 0.994 0.005
E64.0 Sequelae of protein-energy malnutrition
0.000 0.994 0.005
D50.1 Sideropenic dysphagia
0.000 0.994 0.005
N32.3 Diverticulum of bladder
0.006 0.994 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.995 0.005
J32.9 Chronic sinusitis, unspecified
0.005 0.995 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.995 0.005
E27.5 Adrenomedullary hyperfunction
0.000 0.995 0.005
E27.0 Other adrenocortical overactivity
0.000 0.995 0.005
E51.9 Thiamine deficiency, unspecified
0.000 0.995 0.005
E51.8 Other manifestations of thiamine deficiency
0.000 0.995 0.005
E51.1 Beriberi
0.000 0.995 0.005
E53.1 Pyridoxine deficiency
0.000 0.995 0.005
E53.0 Riboflavin deficiency
0.000 0.995 0.005
E04.0 Non-toxic diffuse goitre
0.000 0.995 0.005
E20.8 Other hypoparathyroidism
0.000 0.995 0.005
E20.1 Pseudohypoparathyroidism
0.000 0.995 0.005
E20.0 Idiopathic hypoparathyroidism
0.000 0.995 0.005
E61 Deficiency of other nutrient elements
0.000 0.995 0.005
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.995 0.005
E24 Cushing's syndrome
0.000 0.995 0.005
T38.1 Thyroid hormones and substitutes
0.005 0.995 0.000
T38.9 Other and unspecified hormone antagonists
0.005 0.995 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.005 0.995 0.000
T38.7 Androgens and anabolic congeners
0.005 0.995 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.005 0.995 0.000
T38.5 Other oestrogens and progestogens
0.005 0.995 0.000
T38.4 Oral contraceptives
0.005 0.995 0.000
T38.2 Antithyroid drugs
0.005 0.995 0.000
T38.0 Glucocorticoids and synthetic analogues
0.005 0.995 0.000
E34.0 Carcinoid syndrome
0.000 0.995 0.005
E51.2 Wernicke's encephalopathy
0.000 0.995 0.005
E04.8 Other specified non-toxic goitre
0.000 0.995 0.005
E27.2 Addisonian crisis
0.000 0.995 0.005
T40.4 Other synthetic narcotics
0.005 0.995 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.995 0.005
E28.8 Other ovarian dysfunction
0.000 0.995 0.005
E28.1 Androgen excess
0.000 0.995 0.005
E28.0 Oestrogen excess
0.000 0.995 0.005
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.995 0.005
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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