TreeWAS – Variant ID: rs7762246

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.831	0.169
M48.06 Spinal stenosis (Lumbar region)	0.000	0.980	0.020
M48.02 Spinal stenosis (Cervical region)	0.000	0.982	0.018
M48.0 Spinal stenosis	0.000	0.983	0.017
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.987	0.013
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.988	0.012
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.988	0.012
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.988	0.012
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.988	0.012
M48.04 Spinal stenosis (Thoracic region)	0.000	0.989	0.011
M48.09 Spinal stenosis (Site unspecified)	0.000	0.989	0.011
C78.7 Secondary malignant neoplasm of liver	0.010	0.990	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.990	0.010
Z09.8 Follow-up examination after other treatment for other conditions	0.010	0.990	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.009	0.991	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.009	0.991	0.000
C78.2 Secondary malignant neoplasm of pleura	0.009	0.991	0.000
S72.10 Pertrochanteric fracture (closed)	0.008	0.992	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.008	0.992	0.000
D09.0 Bladder	0.008	0.992	0.000
D26.0 Cervix uteri	0.007	0.993	0.000
R07.0 Pain in throat	0.000	0.993	0.007
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.007	0.993	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.006	0.993	0.000
N64.9 Disorder of breast, unspecified	0.006	0.994	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.994	0.006
R47.1 Dysarthria and anarthria	0.005	0.995	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.995	0.005
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.005
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.995	0.000
D26.1 Corpus uteri	0.005	0.995	0.000
R44.3 Hallucinations, unspecified	0.000	0.995	0.005
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.995	0.005
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.995	0.005
N48.6 Balanitis xerotica obliterans	0.000	0.995	0.005
D26 Other benign neoplasms of uterus	0.005	0.995	0.000
S72.1 Pertrochanteric fracture	0.004	0.995	0.000
N94.6 Dysmenorrhoea, unspecified	0.000	0.996	0.004
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.004	0.996	0.000
N94.1 Dyspareunia	0.000	0.996	0.004
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.996	0.004
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.996	0.004
J92.9 Pleural plaque without asbestos	0.004	0.996	0.000
Z94.0 Kidney transplant status	0.000	0.996	0.004
R44.0 Auditory hallucinations	0.000	0.996	0.004
M48 Other spondylopathies	0.000	0.996	0.004
Y44.2 Anticoagulants	0.004	0.996	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.996	0.003
J92.0 Pleural plaque with presence of asbestos	0.004	0.996	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.000	0.996	0.004
D26.7 Other parts of uterus	0.003	0.996	0.000
S72.11 Pertrochanteric fracture (open)	0.003	0.996	0.000
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.997	0.003
C78.0 Secondary malignant neoplasm of lung	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.997	0.003
R44.1 Visual hallucinations	0.000	0.997	0.003
N99.5 Malfunction of external stoma of urinary tract	0.000	0.997	0.003
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.000	0.997	0.003
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.997	0.003
J92 Pleural plaque	0.003	0.997	0.000
D26.9 Uterus, unspecified	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.003
R44.2 Other hallucinations	0.000	0.997	0.003
R45.1 Restlessness and agitation	0.000	0.997	0.003
H26.8 Other specified cataract	0.000	0.997	0.003
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.997	0.003
M48.4 Fatigue fracture of vertebra	0.000	0.997	0.003
M48.3 Traumatic spondylopathy	0.000	0.997	0.003
M48.2 Kissing spine	0.000	0.997	0.003
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.997	0.003
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.997	0.003
N94.2 Vaginismus	0.000	0.997	0.003
N94.0 Mittelschmerz	0.000	0.997	0.003
N99.1 Postprocedural urethral stricture	0.000	0.997	0.003
D09.9 Carcinoma in situ, unspecified	0.003	0.997	0.000
D09.7 Carcinoma in situ of other specified sites	0.003	0.997	0.000
D09.3 Thyroid and other endocrine glands	0.003	0.997	0.000
D09.2 Eye	0.003	0.997	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.997	0.003
M48.8 Other specified spondylopathies	0.000	0.997	0.002
N48.0 Leukoplakia of penis	0.000	0.997	0.003
D09.1 Other and unspecified urinary organs	0.003	0.997	0.000
M48.9 Spondylopathy, unspecified	0.000	0.997	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.997	0.003
D69 Purpura and other haemorrhagic conditions	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.997	0.003
N48 Other disorders of penis	0.000	0.997	0.003
Z03.1 Observation for suspected malignant neoplasm	0.000	0.997	0.003
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
N48.2 Other inflammatory disorders of penis	0.000	0.998	0.002
N94.4 Primary dysmenorrhoea	0.000	0.998	0.002
N99.2 Postprocedural adhesions of vagina	0.000	0.998	0.002
K76.9 Liver disease, unspecified	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.998	0.002
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.000	0.998	0.002
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.998	0.002
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.998	0.002
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.998	0.002
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.998	0.002
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.998	0.002
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.998	0.002
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.998	0.002
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.998	0.002
M48.29 Kissing spine (Site unspecified)	0.000	0.998	0.002
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.27 Kissing spine (Lumbosacral region)	0.000	0.998	0.002
M48.26 Kissing spine (Lumbar region)	0.000	0.998	0.002
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.998	0.002
M48.24 Kissing spine (Thoracic region)	0.000	0.998	0.002
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.998	0.002
M48.22 Kissing spine (Cervical region)	0.000	0.998	0.002
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.998	0.002
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.998	0.002
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.998	0.002
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.998	0.002
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.998	0.002
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.998	0.002
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.998	0.002
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.998	0.002
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.998	0.002
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.998	0.002
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.998	0.002
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.998	0.002
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.998	0.002
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.998	0.002
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.998	0.002
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.998	0.002
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.998	0.002
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.998	0.002
D69.0 Allergic purpura	0.000	0.998	0.002
N94.5 Secondary dysmenorrhoea	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.998	0.002
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.998	0.002
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.998	0.002
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.998	0.002
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.998	0.002
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.998	0.002
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.998	0.002
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.998	0.002
D51.2 Transcobalamin II deficiency	0.000	0.998	0.002
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.998	0.002
M48.99 Spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
N48.5 Ulcer of penis	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.000	0.998	0.002
M40.26 Other and unspecified kyphosis (Lumbar region)	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
N48.9 Disorder of penis, unspecified	0.000	0.998	0.002
R45.2 Unhappiness	0.000	0.998	0.002
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.998	0.002
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
T86.1 Kidney transplant failure and rejection	0.000	0.998	0.002
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.998	0.002
N48.3 Priapism	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
K76.7 Hepatorenal syndrome	0.002	0.998	0.000
N18.0 End-stage renal disease	0.000	0.998	0.002
K76.6 Portal hypertension	0.002	0.998	0.000
M40.2 Other and unspecified kyphosis	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
N94.3 Premenstrual tension syndrome	0.000	0.998	0.002
R45.0 Nervousness	0.000	0.998	0.002
H54 Blindness and low vision	0.002	0.998	0.000
K76 Other diseases of liver	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
L91.8 Other hypertrophic disorders of skin	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.000	0.998	0.002
T86.0 Bone-marrow transplant rejection	0.000	0.998	0.002
S72 Fracture of femur	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
K73.9 Chronic hepatitis, unspecified	0.002	0.998	0.000
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.002
R45.3 Demoralisation and apathy	0.000	0.998	0.002
M40.24 Other and unspecified kyphosis (Thoracic region)	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
R45.6 Physical violence	0.000	0.998	0.002
Z94.4 Liver transplant status	0.000	0.998	0.002
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.998	0.001
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.998	0.001
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.998	0.001
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.998	0.001
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.998	0.001
H54.5 Low vision, one eye	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
N99.0 Postprocedural renal failure	0.000	0.998	0.001
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.002	0.998	0.000
R00.0 Tachycardia, unspecified	0.000	0.998	0.002
R45.4 Irritability and anger	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.998	0.002
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.001	0.998	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.001	0.998	0.000
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.001	0.998	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.001	0.998	0.000
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.001	0.998	0.000
Z94 Transplanted organ and tissue status	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
Z94.7 Corneal transplant status	0.000	0.998	0.002
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
H54.3 Unqualified visual loss, both eyes	0.001	0.998	0.000
H54.2 Low vision, both eyes	0.001	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
N88.2 Stricture and stenosis of cervix uteri	0.000	0.998	0.002
R45.5 Hostility	0.000	0.998	0.001
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
K76.5 Hepatic veno-occlusive disease	0.001	0.998	0.000
K76.4 Peliosis hepatis	0.001	0.998	0.000
K76.3 Infarction of liver	0.001	0.998	0.000
K76.2 Central haemorrhagic necrosis of liver	0.001	0.998	0.000
O80.0 Spontaneous vertex delivery	0.000	0.998	0.002
R26.3 Immobility	0.000	0.998	0.002
N48.1 Balanoposthitis	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.998	0.001
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.001	0.998	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.001	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.001	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.001	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.001	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.001	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.001	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.001	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.001	0.998	0.000
T42.1 Iminostilbenes	0.001	0.998	0.000
C20 Malignant neoplasm of rectum	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
H65.3 Chronic mucoid otitis media	0.000	0.998	0.002
M23.4 Loose body in knee	0.000	0.998	0.001
S72.9 Fracture of femur, part unspecified	0.001	0.998	0.000
S72.8 Fractures of other parts of femur	0.001	0.998	0.000
S72.7 Multiple fractures of femur	0.001	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
D37.5 Rectum	0.002	0.998	0.000
H11.1 Conjunctival degenerations and deposits	0.001	0.998	0.000
K70.1 Alcoholic hepatitis	0.001	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.998	0.000
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.001	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
D73.0 Hyposplenism	0.001	0.999	0.000
Z91.6 Personal history of other physical trauma	0.000	0.999	0.001
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
D41.4 Bladder	0.001	0.999	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.001	0.999	0.000
R26.0 Ataxic gait	0.000	0.999	0.001
R46.2 Strange and inexplicable behaviour	0.000	0.999	0.001
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.999	0.001
Z94.6 Bone transplant status	0.000	0.999	0.001
Z94.5 Skin transplant status	0.000	0.999	0.001
Z94.3 Heart and lungs transplant status	0.000	0.999	0.001
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.999	0.000
Y44.7 Plasma substitutes	0.001	0.999	0.000
Y44.6 Natural blood and blood products	0.001	0.999	0.000
Y44.5 Thrombolytic drugs	0.001	0.999	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.999	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.999	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.999	0.000
K20 Oesophagitis	0.000	0.999	0.001
K38.1 Appendicular concretions	0.001	0.999	0.000
K86.8 Other specified diseases of pancreas	0.001	0.999	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
D73.3 Abscess of spleen	0.001	0.999	0.000
K56.1 Intussusception	0.000	0.999	0.001
R26.1 Paralytic gait	0.000	0.999	0.001
D75.0 Familial erythrocytosis	0.001	0.999	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.999	0.001
Q66.7 Pes cavus	0.001	0.999	0.000
R63.0 Anorexia	0.000	0.999	0.001
D75 Other diseases of blood and blood-forming organs	0.001	0.999	0.000
M23.47 Loose body in knee-Capsular lig	0.000	0.999	0.001
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.999	0.001
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.999	0.001
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.999	0.001
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.999	0.001
M23.40 Loose body in knee-Mult sites	0.000	0.999	0.001
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.001	0.999	0.001
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.999	0.000
D73.9 Disease of spleen, unspecified	0.001	0.999	0.000
D73.8 Other diseases of spleen	0.001	0.999	0.000
D73.2 Chronic congestive splenomegaly	0.001	0.999	0.000
G59.0 Diabetic mononeuropathy	0.000	0.999	0.001
K14.0 Glossitis	0.000	0.999	0.001
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
T40.2 Other opioids	0.001	0.999	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.999	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.999	0.000
T42.3 Barbiturates	0.001	0.999	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.999	0.000
R46 Symptoms and signs involving appearance and behaviour	0.000	0.999	0.001
D73.4 Cyst of spleen	0.001	0.999	0.000
K73 Chronic hepatitis, not elsewhere classified	0.001	0.999	0.000
D73.1 Hypersplenism	0.001	0.999	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.999	0.001
Q66.2 Metatarsus varus	0.001	0.999	0.000
S72.2 Subtrochanteric fracture	0.001	0.999	0.000
S82.3 Fracture of lower end of tibia	0.001	0.999	0.000
M23.46 Loose body in knee-O/unsp lat men	0.000	0.999	0.001
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.999	0.001
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
Q66 Congenital deformities of feet	0.001	0.999	0.000
C45.7 Mesothelioma of other sites	0.000	0.999	0.001
D75.1 Secondary polycythaemia	0.001	0.999	0.000
E11.4 With neurological complications	0.000	0.999	0.001
H35.0 Background retinopathy and retinal vascular changes	0.001	0.999	0.000
H54.4 Blindness, one eye	0.001	0.999	0.000
L90.0 Lichen sclerosus et atrophicus	0.001	0.999	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.999	0.001
C45 Mesothelioma	0.000	0.999	0.001
D37.1 Stomach	0.001	0.999	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.001	0.999	0.000
K70.4 Alcoholic hepatic failure	0.001	0.999	0.000
M43.0 Spondylolysis	0.001	0.999	0.000
M40.56 Lordosis, unspecified (Lumbar region)	0.001	0.999	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.001	0.999	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.999	0.001
Z94.2 Lung transplant status	0.000	0.999	0.001
Q76 Congenital malformations of spine and bony thorax	0.001	0.999	0.000
N99-N99 Other disorders of the genitourinary system	0.000	0.999	0.001
S72.31 Fracture of shaft of femur (open)	0.001	0.999	0.000
S82.60 Fracture of lateral malleolus (closed)	0.001	0.999	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
E85.4 Organ-limited amyloidosis	0.001	0.999	0.000
M40.5 Lordosis, unspecified	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
M40 Kyphosis and lordosis	0.001	0.999	0.000
T86 Failure and rejection of transplanted organs and tissues	0.000	0.999	0.001
C80.9 Malignant neoplasm, unspecified	0.001	0.999	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.001	0.999	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.001	0.999	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.001	0.999	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.999	0.001
R46.6 Undue concern and preoccupation with stressful events	0.000	0.999	0.001
R46.5 Suspiciousness and marked evasiveness	0.000	0.999	0.001
R46.3 Overactivity	0.000	0.999	0.001
R46.1 Bizarre personal appearance	0.000	0.999	0.001
R46.0 Very low level of personal hygiene	0.000	0.999	0.001
S43.0 Dislocation of shoulder joint	0.001	0.999	0.000
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.001	0.999	0.000
R46.4 Slowness and poor responsiveness	0.000	0.999	0.001
R48.0 Dyslexia and alexia	0.001	0.999	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
Z94.1 Heart transplant status	0.000	0.999	0.001
M53.86 Other specified dorsopathies (Lumbar region)	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.000	0.999	0.001
C45.1 Mesothelioma of peritoneum	0.000	0.999	0.001
M31.3 Wegener's granulomatosis	0.000	0.999	0.001
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
S71.1 Open wound of thigh	0.000	0.999	0.001
Z36.9 Antenatal screening, unspecified	0.000	0.999	0.001
B25 Cytomegaloviral disease	0.000	0.999	0.001
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.999	0.001
M43.09 Spondylolysis (Site unspecified)	0.001	0.999	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.001	0.999	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.001	0.999	0.000
M43.04 Spondylolysis (Thoracic region)	0.001	0.999	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.001	0.999	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.001	0.999	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.001	0.999	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.001	0.999	0.000
K70 Alcoholic liver disease	0.001	0.999	0.000
N64 Other disorders of breast	0.001	0.999	0.000
M23.43 Loose body in knee-Med lig/oth men	0.000	0.999	0.001
M40.59 Lordosis, unspecified (Site unspecified)	0.001	0.999	0.000
M40.58 Lordosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M40.57 Lordosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M40.55 Lordosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M40.54 Lordosis, unspecified (Thoracic region)	0.001	0.999	0.000
M40.53 Lordosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M40.52 Lordosis, unspecified (Cervical region)	0.001	0.999	0.000
M40.51 Lordosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M40.50 Lordosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.999	0.001
M40.4 Other lordosis	0.001	0.999	0.000
M40.3 Flatback syndrome	0.001	0.999	0.000
M40.1 Other secondary kyphosis	0.001	0.999	0.000
M40.0 Postural kyphosis	0.001	0.999	0.000
N48.8 Other specified disorders of penis	0.000	0.999	0.001
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.999	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.999	0.000
Q76.7 Congenital malformation of sternum	0.001	0.999	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.999	0.000
Q76.5 Cervical rib	0.001	0.999	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.999	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.999	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.999	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.999	0.001
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.999	0.001
T86.3 Heart-lung transplant failure and rejection	0.000	0.999	0.001
T86.2 Heart transplant failure and rejection	0.000	0.999	0.001
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.999	0.001
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.999	0.001
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.999	0.001
B25.8 Other cytomegaloviral diseases	0.000	0.999	0.001
B25.2 Cytomegaloviral pancreatitis	0.000	0.999	0.001
B25.1 Cytomegaloviral hepatitis	0.000	0.999	0.001
B25.0 Cytomegaloviral pneumonitis	0.000	0.999	0.001
E11.5 With peripheral circulatory complications	0.000	0.999	0.001
G90.9 Disorder of autonomic nervous system, unspecified	0.001	0.999	0.000
K13.5 Oral submucous fibrosis	0.001	0.999	0.000
K70.9 Alcoholic liver disease, unspecified	0.001	0.999	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.999	0.000
N64.4 Mastodynia	0.001	0.999	0.000
N64.3 Galactorrhoea not associated with childbirth	0.001	0.999	0.000
N64.2 Atrophy of breast	0.001	0.999	0.000
N64.0 Fissure and fistula of nipple	0.001	0.999	0.000
W06.0 Home	0.001	0.999	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.999	0.001
N63 Unspecified lump in breast	0.000	0.999	0.001
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.001	0.999	0.000
M40.09 Postural kyphosis (Site unspecified)	0.001	0.999	0.000
M40.08 Postural kyphosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M40.07 Postural kyphosis (Lumbosacral region)	0.001	0.999	0.000
M40.06 Postural kyphosis (Lumbar region)	0.001	0.999	0.000
M40.05 Postural kyphosis (Thoracolumbar region)	0.001	0.999	0.000
M40.04 Postural kyphosis (Thoracic region)	0.001	0.999	0.000
M40.03 Postural kyphosis (Cervicothoracic region)	0.001	0.999	0.000
M40.02 Postural kyphosis (Cervical region)	0.001	0.999	0.000
M40.01 Postural kyphosis (Occipito-atlanto-axial region)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations