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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7762253
log Bayes Factor = 33.492
Chromosome 6   position 29,676,823  (GRCh37) Explore rs7762253 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.053 0.947
E05.9 Thyrotoxicosis, unspecified
0.000 0.055 0.945
E00-E07 Disorders of thyroid gland
0.000 0.068 0.932
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.070 0.930
E06 Thyroiditis
0.000 0.075 0.925
E03 Other hypothyroidism
0.000 0.094 0.906
E06.3 Autoimmune thyroiditis
0.000 0.101 0.899
E03.9 Hypothyroidism, unspecified
0.000 0.106 0.894
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.114 0.886
E06.9 Thyroiditis, unspecified
0.000 0.130 0.870
G37 Other demyelinating diseases of central nervous system
0.000 0.137 0.863
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.160 0.840
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.182 0.818
E06.5 Other chronic thyroiditis
0.000 0.282 0.717
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.288 0.712
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.291 0.709
E07 Other disorders of thyroid
0.000 0.313 0.687
E05.5 Thyroid crisis or storm
0.000 0.321 0.679
E05.4 Thyrotoxicosis factitia
0.000 0.321 0.679
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.321 0.679
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.321 0.679
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.332 0.668
E00 Congenital iodine-deficiency syndrome
0.000 0.332 0.668
E06.4 Drug-induced thyroiditis
0.000 0.337 0.663
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.337 0.663
E06.0 Acute thyroiditis
0.000 0.337 0.663
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.339 0.661
E03.5 Myxoedema coma
0.000 0.350 0.650
E03.4 Atrophy of thyroid (acquired)
0.000 0.350 0.650
E03.3 Postinfectious hypothyroidism
0.000 0.350 0.650
G36 Other acute disseminated demyelination
0.000 0.364 0.636
G37.5 Concentric sclerosis [Balo]
0.000 0.381 0.618
G37.4 Subacute necrotising myelitis
0.000 0.381 0.618
G37.2 Central pontine myelinolysis
0.000 0.381 0.618
G37.1 Central demyelination of corpus callosum
0.000 0.381 0.618
G37.0 Diffuse sclerosis
0.000 0.381 0.618
E06.1 Subacute thyroiditis
0.000 0.403 0.597
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.421 0.579
E07.8 Other specified disorders of thyroid
0.000 0.445 0.555
E03.1 Congenital hypothyroidism without goitre
0.000 0.452 0.547
E03.8 Other specified hypothyroidism
0.000 0.456 0.544
E05.8 Other thyrotoxicosis
0.000 0.462 0.538
E07.1 Dyshormogenetic goitre
0.000 0.507 0.493
E07.0 Hypersecretion of calcitonin
0.000 0.507 0.493
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.521 0.479
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.521 0.479
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.521 0.479
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.521 0.479
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.521 0.479
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.521 0.479
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.521 0.479
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.521 0.479
E02 Subclinical iodine-deficiency hypothyroidism
0.001 0.526 0.474
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.535 0.465
G36.0 Neuromyelitis optica [Devic]
0.000 0.543 0.457
G36.9 Acute disseminated demyelination, unspecified
0.000 0.544 0.456
G36.8 Other specified acute disseminated demyelination
0.000 0.544 0.456
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.544 0.456
E07.9 Disorder of thyroid, unspecified
0.000 0.572 0.428
I71 Aortic aneurysm and dissection
0.000 0.578 0.422
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.614 0.386
I73 Other peripheral vascular diseases
0.000 0.636 0.364
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.642 0.358
I73.9 Peripheral vascular disease, unspecified
0.000 0.648 0.352
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.653 0.347
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.657 0.343
I74 Arterial embolism and thrombosis
0.000 0.670 0.330
I72 Other aneurysm
0.000 0.675 0.325
E83 Disorders of mineral metabolism
0.000 0.681 0.319
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.683 0.317
K90 Intestinal malabsorption
0.000 0.688 0.312
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.697 0.303
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.697 0.303
I70 Atherosclerosis
0.000 0.701 0.299
I72.4 Aneurysm of artery of lower extremity
0.000 0.708 0.292
I74.8 Embolism and thrombosis of other arteries
0.000 0.715 0.285
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.715 0.285
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.716 0.284
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.717 0.283
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.718 0.282
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.720 0.280
I84.9 Unspecified haemorrhoids without complication
0.280 0.720 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.733 0.267
E83.3 Disorders of phosphorus metabolism
0.000 0.738 0.262
I72.9 Aneurysm of unspecified site
0.000 0.743 0.257
I72.1 Aneurysm of artery of upper extremity
0.000 0.745 0.255
I71.0 Dissection of aorta [any part]
0.000 0.746 0.254
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.746 0.254
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.750 0.250
I73.8 Other specified peripheral vascular diseases
0.000 0.751 0.249
I79.1 Aortitis in diseases classified elsewhere
0.000 0.754 0.246
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.754 0.246
I72.8 Aneurysm of other specified arteries
0.000 0.755 0.245
I70.8 Atherosclerosis of other arteries
0.000 0.760 0.239
I77 Other disorders of arteries and arterioles
0.000 0.767 0.233
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.767 0.233
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.767 0.233
K90.9 Intestinal malabsorption, unspecified
0.000 0.768 0.232
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.771 0.229
E83.8 Other disorders of mineral metabolism
0.000 0.771 0.229
E83.2 Disorders of zinc metabolism
0.000 0.771 0.229
E83.0 Disorders of copper metabolism
0.000 0.771 0.229
K90.8 Other intestinal malabsorption
0.000 0.774 0.226
I72.2 Aneurysm of renal artery
0.000 0.775 0.225
I70.0 Atherosclerosis of aorta
0.000 0.775 0.225
K90.3 Pancreatic steatorrhoea
0.000 0.776 0.224
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.776 0.224
K90.1 Tropical sprue
0.000 0.776 0.224
I73.0 Raynaud's syndrome
0.000 0.779 0.221
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.780 0.220
I70.1 Atherosclerosis of renal artery
0.000 0.782 0.218
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.783 0.217
I70.9 Generalised and unspecified atherosclerosis
0.000 0.789 0.211
I77.2 Rupture of artery
0.000 0.791 0.209
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.801 0.199
I77.8 Other specified disorders of arteries and arterioles
0.000 0.802 0.198
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.803 0.197
E83.5 Disorders of calcium metabolism
0.000 0.813 0.187
M35.0 Sicca syndrome [Sjogren]
0.000 0.818 0.182
I72.3 Aneurysm of iliac artery
0.000 0.819 0.180
I72.0 Aneurysm of carotid artery
0.000 0.825 0.175
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.825 0.175
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.828 0.172
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.829 0.171
I77.5 Necrosis of artery
0.000 0.833 0.167
I77.4 Coeliac artery compression syndrome
0.000 0.833 0.167
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.833 0.167
I77.3 Arterial fibromuscular dysplasia
0.000 0.834 0.166
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.839 0.161
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.841 0.159
E70-E90 Metabolic disorders
0.000 0.841 0.159
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.842 0.158
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.843 0.157
E89.0 Postprocedural hypothyroidism
0.000 0.843 0.157
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.844 0.156
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.845 0.155
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.849 0.151
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.853 0.147
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.853 0.147
I77.6 Arteritis, unspecified
0.000 0.857 0.143
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.858 0.142
E89.2 Postprocedural hypoparathyroidism
0.000 0.865 0.135
S06.3 Focal brain injury
0.000 0.875 0.125
E40-E46 Malnutrition
0.000 0.878 0.122
E89.4 Postprocedural ovarian failure
0.000 0.882 0.118
E76 Disorders of glycosaminoglycan metabolism
0.000 0.886 0.114
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.886 0.114
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.886 0.114
E73 Lactose intolerance
0.000 0.886 0.114
E70 Disorders of aromatic amino-acid metabolism
0.000 0.888 0.112
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.889 0.111
E89.1 Postprocedural hypoinsulinaemia
0.000 0.889 0.111
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.890 0.110
E77 Disorders of glycoprotein metabolism
0.000 0.891 0.109
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.891 0.109
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.891 0.108
E84 Cystic fibrosis
0.000 0.892 0.108
E74 Other disorders of carbohydrate metabolism
0.000 0.893 0.107
I78 Diseases of capillaries
0.000 0.894 0.106
I77.0 Arteriovenous fistula, acquired
0.000 0.896 0.104
S06 Intracranial injury
0.000 0.897 0.103
E04 Other non-toxic goitre
0.000 0.899 0.101
E72 Other disorders of amino-acid metabolism
0.000 0.900 0.100
I74.5 Embolism and thrombosis of iliac artery
0.000 0.900 0.100
S06.5 Traumatic subdural haemorrhage
0.000 0.901 0.099
E79 Disorders of purine and pyrimidine metabolism
0.000 0.902 0.097
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.903 0.097
E46 Unspecified protein-energy malnutrition
0.000 0.903 0.097
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.908 0.092
E80.6 Other disorders of bilirubin metabolism
0.000 0.908 0.092
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.910 0.090
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.911 0.089
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.912 0.088
E45 Retarded development following protein-energy malnutrition
0.000 0.912 0.088
E43 Unspecified severe protein-energy malnutrition
0.000 0.912 0.088
E42 Marasmic kwashiorkor
0.000 0.912 0.088
E41 Nutritional marasmus
0.000 0.912 0.088
E40 Kwashiorkor
0.000 0.912 0.088
K50.9 Crohn's disease, unspecified
0.086 0.914 0.000
E88 Other metabolic disorders
0.000 0.916 0.084
E80.1 Porphyria cutanea tarda
0.000 0.916 0.084
E89.5 Postprocedural testicular hypofunction
0.000 0.917 0.083
E84.9 Cystic fibrosis, unspecified
0.000 0.917 0.083
E75.5 Other lipid storage disorders
0.000 0.918 0.082
K50 Crohn's disease [regional enteritis]
0.082 0.918 0.000
E71.3 Disorders of fatty-acid metabolism
0.000 0.918 0.082
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.918 0.082
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.918 0.082
E71.0 Maple-syrup-urine disease
0.000 0.918 0.082
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.918 0.082
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.918 0.082
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.918 0.082
E76.2 Other mucopolysaccharidoses
0.000 0.918 0.082
E76.1 Mucopolysaccharidosis, type II
0.000 0.918 0.082
E76.0 Mucopolysaccharidosis, type I
0.000 0.918 0.082
E73.8 Other lactose intolerance
0.000 0.918 0.082
E73.1 Secondary lactase deficiency
0.000 0.918 0.082
E73.0 Congenital lactase deficiency
0.000 0.918 0.082
E73.9 Lactose intolerance, unspecified
0.000 0.918 0.081
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.919 0.080
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.919 0.080
E70.2 Disorders of tyrosine metabolism
0.000 0.919 0.080
E70.1 Other hyperphenylalaninaemias
0.000 0.919 0.080
E70.0 Classical phenylketonuria
0.000 0.919 0.080
K50.8 Other Crohn's disease
0.080 0.920 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.921 0.079
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.921 0.079
E75.3 Sphingolipidosis, unspecified
0.000 0.921 0.079
E75.1 Other gangliosidosis
0.000 0.921 0.079
E75.0 GM2 gangliosidosis
0.000 0.921 0.079
S06.1 Traumatic cerebral oedema
0.000 0.921 0.079
E70.3 Albinism
0.000 0.921 0.078
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.921 0.079
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.922 0.078
E77.1 Defects in glycoprotein degradation
0.000 0.922 0.078
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.922 0.078
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.922 0.078
E80.5 Crigler-Najjar syndrome
0.000 0.922 0.078
E80.3 Defects of catalase and peroxydase
0.000 0.922 0.078
E80.0 Hereditary erythropoietic porphyria
0.000 0.922 0.078
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.922 0.078
E84.8 Cystic fibrosis with other manifestations
0.000 0.922 0.078
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.922 0.078
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.923 0.077
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.923 0.077
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.923 0.077
E74.2 Disorders of galactose metabolism
0.000 0.923 0.077
E74.1 Disorders of fructose metabolism
0.000 0.923 0.077
M35 Other systemic involvement of connective tissue
0.000 0.924 0.076
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.924 0.076
E74.0 Glycogen storage disease
0.000 0.924 0.076
S06.7 Intracranial injury with prolonged coma
0.000 0.926 0.074
E77.8 Other disorders of glycoprotein metabolism
0.000 0.927 0.073
I77.1 Stricture of artery
0.000 0.927 0.073
E04.8 Other specified non-toxic goitre
0.000 0.927 0.073
E75.2 Other sphingolipidosis
0.000 0.928 0.072
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.928 0.072
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.928 0.072
E72.5 Disorders of glycine metabolism
0.000 0.928 0.072
E72.4 Disorders of ornithine metabolism
0.000 0.928 0.072
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.928 0.072
E72.2 Disorders of urea cycle metabolism
0.000 0.928 0.072
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.929 0.071
S06.9 Intracranial injury, unspecified
0.000 0.929 0.071
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.929 0.071
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.930 0.070
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.930 0.070
E79.1 Lesch-Nyhan syndrome
0.000 0.930 0.070
I78.9 Disease of capillaries, unspecified
0.000 0.930 0.070
E04.0 Non-toxic diffuse goitre
0.000 0.931 0.069
K51.2 Ulcerative (chronic) proctitis
0.069 0.931 0.000
E72.0 Disorders of amino-acid transport
0.000 0.931 0.068
K51 Ulcerative colitis
0.068 0.932 0.000
S06.0 Concussion
0.000 0.932 0.068
S06.4 Epidural haemorrhage
0.000 0.933 0.067
E80.2 Other porphyria
0.000 0.933 0.066
S06.8 Other intracranial injuries
0.000 0.933 0.066
K50-K52 Noninfective enteritis and colitis
0.066 0.934 0.000
M35.7 Hypermobility syndrome
0.000 0.935 0.065
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.935 0.064
S06.2 Diffuse brain injury
0.000 0.936 0.064
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.936 0.064
E88.9 Metabolic disorder, unspecified
0.000 0.937 0.063
E44.1 Mild protein-energy malnutrition
0.000 0.937 0.063
E44.0 Moderate protein-energy malnutrition
0.000 0.937 0.063
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.937 0.063
I78.8 Other diseases of capillaries
0.000 0.937 0.063
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.000 0.937 0.063
E89.3 Postprocedural hypopituitarism
0.000 0.938 0.062
E65-E68 Obesity and other hyperalimentation
0.000 0.939 0.061
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.940 0.060
E88.2 Lipomatosis, not elsewhere classified
0.000 0.941 0.059
K51.0 Ulcerative (chronic) enterocolitis
0.059 0.941 0.000
K51.5 Mucosal proctocolitis
0.059 0.941 0.000
E88.3 Tumour lysis syndrome
0.000 0.942 0.058
K50.0 Crohn's disease of small intestine
0.058 0.942 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.943 0.057
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.000 0.943 0.057
K51.8 Other ulcerative colitis
0.057 0.943 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.944 0.056
E86 Volume depletion
0.000 0.945 0.055
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.945 0.055
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.945 0.055
M35.5 Multifocal fibrosclerosis
0.000 0.945 0.055
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.945 0.055
E88.8 Other specified metabolic disorders
0.000 0.946 0.054
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.946 0.053
K51.1 Ulcerative (chronic) ileocolitis
0.054 0.946 0.000
M35.1 Other overlap syndromes
0.000 0.946 0.054
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.947 0.053
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.947 0.053
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.000 0.949 0.051
E80.4 Gilbert's syndrome
0.000 0.949 0.051
I78.1 Naevus, nonneoplastic
0.000 0.949 0.051
S06.01 Concussion (with open intracranial wound)
0.000 0.951 0.049
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.000 0.951 0.049
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.951 0.048
M35.8 Other specified systemic involvement of connective tissue
0.000 0.952 0.048
E50-E64 Other nutritional deficiencies
0.000 0.952 0.048
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.952 0.048
M35.2 Behcet's disease
0.000 0.953 0.047
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.954 0.046
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.954 0.046
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.954 0.045
K50.1 Crohn's disease of large intestine
0.046 0.954 0.000
E67 Other hyperalimentation
0.000 0.956 0.044
E68 Sequelae of hyperalimentation
0.000 0.956 0.044
M35.3 Polymyalgia rheumatica
0.000 0.957 0.043
K51.4 Pseudopolyposis of colon
0.043 0.957 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.957 0.043
S06.00 Concussion (without open intracranial wound)
0.000 0.957 0.043
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.958 0.042
E85 Amyloidosis
0.002 0.959 0.039
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.959 0.041
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.959 0.041
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.960 0.039
E65 Localised adiposity
0.000 0.962 0.038
E51 Thiamine deficiency
0.000 0.963 0.036
E04.9 Non-toxic goitre, unspecified
0.000 0.963 0.036
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.964 0.036
K51.3 Ulcerative (chronic) rectosigmoiditis
0.036 0.964 0.000
E56 Other vitamin deficiencies
0.000 0.965 0.035
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.965 0.035
E63 Other nutritional deficiencies
0.000 0.965 0.035
E50 Vitamin A deficiency
0.000 0.965 0.035
E60 Dietary zinc deficiency
0.000 0.965 0.035
E59 Dietary selenium deficiency
0.000 0.965 0.035
E52 Niacin deficiency [pellagra]
0.000 0.965 0.035
E78.4 Other hyperlipidaemia
0.000 0.966 0.034
K51.9 Ulcerative colitis, unspecified
0.034 0.966 0.000
E78.6 Lipoprotein deficiency
0.000 0.967 0.033
E78.3 Hyperchylomicronaemia
0.000 0.968 0.032
E67.8 Other specified hyperalimentation
0.000 0.968 0.032
E67.3 Hypervitaminosis D
0.000 0.968 0.032
E67.2 Megavitamin-B6 syndrome
0.000 0.968 0.032
E67.1 Hypercarotenaemia
0.000 0.968 0.032
E67.0 Hypervitaminosis A
0.000 0.968 0.032
E58 Dietary calcium deficiency
0.000 0.968 0.032
E55 Vitamin D deficiency
0.000 0.969 0.030
E54 Ascorbic acid deficiency
0.000 0.970 0.030
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.970 0.028
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.970 0.028
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.970 0.028
E85.8 Other amyloidosis
0.001 0.971 0.028
E51.2 Wernicke's encephalopathy
0.000 0.972 0.028
E51.9 Thiamine deficiency, unspecified
0.000 0.974 0.026
E51.8 Other manifestations of thiamine deficiency
0.000 0.974 0.026
E51.1 Beriberi
0.000 0.974 0.026
E78.2 Mixed hyperlipidaemia
0.000 0.974 0.026
E53 Deficiency of other B group vitamins
0.000 0.974 0.026
E78.1 Pure hyperglyceridaemia
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.974 0.026
M24.27 Disorder of ligament (Ankle and foot)
0.000 0.974 0.026
M24.2 Disorder of ligament
0.000 0.975 0.025
E56.1 Deficiency of vitamin K
0.000 0.975 0.025
E56.9 Vitamin deficiency, unspecified
0.000 0.975 0.025
E56.8 Deficiency of other vitamins
0.000 0.975 0.025
E56.0 Deficiency of vitamin E
0.000 0.975 0.025
M20-M25 Other joint disorders
0.000 0.975 0.025
E50.9 Vitamin A deficiency, unspecified
0.000 0.975 0.025
E50.8 Other manifestations of vitamin A deficiency
0.000 0.975 0.025
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.975 0.025
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.975 0.025
E50.5 Vitamin A deficiency with night blindness
0.000 0.975 0.025
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.975 0.025
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.975 0.025
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.975 0.025
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.975 0.025
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.975 0.025
E63.9 Nutritional deficiency, unspecified
0.000 0.975 0.025
E63.8 Other specified nutritional deficiencies
0.000 0.975 0.025
E63.1 Imbalance of constituents of food intake
0.000 0.975 0.025
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.975 0.025
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.975 0.025
E64.8 Sequelae of other nutritional deficiencies
0.000 0.975 0.025
E64.3 Sequelae of rickets
0.000 0.975 0.025
E64.2 Sequelae of vitamin C deficiency
0.000 0.975 0.025
E64.1 Sequelae of vitamin A deficiency
0.000 0.975 0.025
E64.0 Sequelae of protein-energy malnutrition
0.000 0.975 0.025
R31 Unspecified haematuria
0.025 0.975 0.000
M24 Other specific joint derangements
0.000 0.975 0.025
M31 Other necrotising vasculopathies
0.000 0.976 0.024
E85.3 Secondary systemic amyloidosis
0.002 0.977 0.021
E04.2 Non-toxic multinodular goitre
0.000 0.977 0.023
E55.0 Rickets, active
0.000 0.978 0.022
E10-E14 Diabetes mellitus
0.000 0.978 0.022
M24.21 Disorder of ligament (Shoulder region)
0.000 0.978 0.022
M22 Disorders of patella
0.000 0.978 0.022
E85.4 Organ-limited amyloidosis
0.002 0.978 0.020
M24.8 Other specific joint derangements, not elsewhere classified
0.000 0.979 0.021
M24.28 Disorder of ligament (Other)
0.000 0.979 0.021
M31.6 Other giant cell arteritis
0.000 0.979 0.021
E61 Deficiency of other nutrient elements
0.000 0.979 0.021
M32 Systemic lupus erythematosus
0.000 0.979 0.021
E16 Other disorders of pancreatic internal secretion
0.000 0.979 0.021
M31.1 Thrombotic microangiopathy
0.000 0.980 0.020
M34 Systemic sclerosis
0.000 0.980 0.020
M24.23 Disorder of ligament (Forearm)
0.000 0.980 0.020
M22.2 Patellofemoral disorders
0.000 0.981 0.019
E53.1 Pyridoxine deficiency
0.000 0.981 0.019
E53.0 Riboflavin deficiency
0.000 0.981 0.019
M24.0 Loose body in joint
0.000 0.981 0.019
M24.4 Recurrent dislocation and subluxation of joint
0.000 0.981 0.019
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.019
M31.9 Necrotising vasculopathy, unspecified
0.000 0.981 0.019
M22.3 Other derangements of patella
0.000 0.981 0.019
E20-E35 Disorders of other endocrine glands
0.000 0.981 0.019
M24.29 Disorder of ligament (Site unspecified)
0.000 0.981 0.018
M24.25 Disorder of ligament (Pelvic region and thigh)
0.000 0.981 0.018
M24.22 Disorder of ligament (Upper arm)
0.000 0.981 0.018
M24.20 Disorder of ligament (Multiple sites)
0.000 0.981 0.018
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.982 0.018
M34.8 Other forms of systemic sclerosis
0.000 0.982 0.018
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.982 0.018
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.982 0.018
E55.9 Vitamin D deficiency, unspecified
0.000 0.982 0.018
M22.4 Chondromalacia patellae
0.000 0.982 0.018
E53.9 Vitamin B deficiency, unspecified
0.000 0.983 0.017
E13 Other specified diabetes mellitus
0.000 0.983 0.017
M22.9 Disorder of patella, unspecified
0.000 0.983 0.017
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.000 0.983 0.017
M31.7 Microscopic polyangiitis
0.000 0.983 0.017
M31.2 Lethal midline granuloma
0.000 0.983 0.017
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.000 0.983 0.017
M24.7 Protrusio acetabuli
0.000 0.983 0.017
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.983 0.017
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.000 0.983 0.017
M24.9 Joint derangement, unspecified
0.000 0.983 0.017
E27.1 Primary adrenocortical insufficiency
0.000 0.983 0.017
M31.8 Other specified necrotising vasculopathies
0.000 0.983 0.017
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.000 0.983 0.017
M24.6 Ankylosis of joint
0.000 0.983 0.017
M24.07 Loose body in joint (Ankle and foot)
0.000 0.983 0.017
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.000 0.983 0.016
M30 Polyarteritis nodosa and related conditions
0.000 0.983 0.016
E20 Hypoparathyroidism
0.000 0.984 0.016
M31.0 Hypersensitivity angiitis
0.000 0.984 0.016
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.000 0.984 0.016
E12 Malnutrition-related diabetes mellitus
0.000 0.984 0.016
M33 Dermatopolymyositis
0.000 0.984 0.016
M24.04 Loose body in joint (Hand)
0.000 0.984 0.016
M22.1 Recurrent subluxation of patella
0.000 0.984 0.016
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.000 0.984 0.016
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.000 0.984 0.016
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.000 0.984 0.016
M24.24 Disorder of ligament (Hand)
0.000 0.984 0.015
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.000 0.984 0.015
M32.8 Other forms of systemic lupus erythematosus
0.000 0.984 0.015
E61.9 Deficiency of nutrient element, unspecified
0.000 0.985 0.015
E61.8 Deficiency of other specified nutrient elements
0.000 0.985 0.015
E61.7 Deficiency of multiple nutrient elements
0.000 0.985 0.015
E61.6 Vanadium deficiency
0.000 0.985 0.015
E61.5 Molybdenum deficiency
0.000 0.985 0.015
E61.4 Chromium deficiency
0.000 0.985 0.015
E61.3 Manganese deficiency
0.000 0.985 0.015
E61.0 Copper deficiency
0.000 0.985 0.015
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.000 0.985 0.015
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.985 0.015
E25 Adrenogenital disorders
0.000 0.985 0.015
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.985 0.015
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.985 0.015
E16.4 Abnormal secretion of gastrin
0.000 0.985 0.015
E16.3 Increased secretion of glucagon
0.000 0.985 0.015
E04.1 Non-toxic single thyroid nodule
0.000 0.985 0.015
M31.3 Wegener's granulomatosis
0.000 0.985 0.015
M34.0 Progressive systemic sclerosis
0.000 0.985 0.015
E27 Other disorders of adrenal gland
0.000 0.985 0.015
M24.05 Loose body in joint (Pelvic region and thigh)
0.000 0.985 0.015
E20.9 Hypoparathyroidism, unspecified
0.000 0.985 0.015
M24.5 Contracture of joint
0.000 0.985 0.015
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.985 0.014
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.985 0.014
E78.8 Other disorders of lipoprotein metabolism
0.000 0.986 0.014
M24.66 Ankylosis of joint (Lower leg)
0.000 0.986 0.014
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.000 0.986 0.014
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.000 0.986 0.014
M24.09 Loose body in joint (Site unspecified)
0.000 0.986 0.014
M24.08 Loose body in joint (Other)
0.000 0.986 0.014
M24.00 Loose body in joint (Multiple sites)
0.000 0.986 0.014
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.000 0.986 0.014
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.000 0.986 0.014
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.000 0.986 0.014
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.000 0.986 0.014
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.000 0.986 0.014
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.000 0.986 0.014
E31 Polyglandular dysfunction
0.000 0.986 0.014
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.000 0.986 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.013
E13.9 Without complications
0.000 0.986 0.014
M22.0 Recurrent dislocation of patella
0.000 0.986 0.014
E53.8 Deficiency of other specified B group vitamins
0.000 0.986 0.014
E85.9 Amyloidosis, unspecified
0.003 0.986 0.011
M24.01 Loose body in joint (Shoulder region)
0.000 0.986 0.014
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.986 0.013
E32 Diseases of thymus
0.000 0.986 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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