TreeWAS – Variant ID: rs7765175

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H02.4 Ptosis of eyelid	0.506	0.494	0.000
H02.6 Xanthelasma of eyelid	0.460	0.540	0.000
H02 Other disorders of eyelid	0.456	0.544	0.000
H02.9 Disorder of eyelid, unspecified	0.437	0.563	0.000
H02.8 Other specified disorders of eyelid	0.350	0.650	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.327	0.673	0.000
H02.2 Lagophthalmos	0.280	0.720	0.000
H02.3 Blepharochalasis	0.233	0.767	0.000
H02.5 Other disorders affecting eyelid function	0.204	0.796	0.000
C15.5 Lower third of oesophagus	0.124	0.876	0.000
C15 Malignant neoplasm of oesophagus	0.121	0.879	0.000
C15.9 Oesophagus, unspecified	0.119	0.881	0.000
C15.4 Middle third of oesophagus	0.110	0.889	0.000
H02.1 Ectropion of eyelid	0.105	0.895	0.000
C15.1 Thoracic part of oesophagus	0.102	0.898	0.000
C15.0 Cervical part of oesophagus	0.089	0.911	0.000
C15.8 Overlapping lesion of oesophagus	0.087	0.913	0.000
C15.2 Abdominal part of oesophagus	0.087	0.913	0.000
C15.3 Upper third of oesophagus	0.079	0.921	0.000
J81 Pulmonary oedema	0.062	0.938	0.000
H02.0 Entropion and trichiasis of eyelid	0.053	0.947	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.029	0.971	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.026	0.974	0.000
C34.3 Lower lobe, bronchus or lung	0.024	0.976	0.000
H06.2 Dysthyroid exophthalmos	0.024	0.976	0.000
C34 Malignant neoplasm of bronchus and lung	0.023	0.977	0.000
C34.0 Main bronchus	0.022	0.978	0.000
C34.9 Bronchus or lung, unspecified	0.020	0.980	0.000
H83.0 Labyrinthitis	0.020	0.980	0.000
H83 Other diseases of inner ear	0.020	0.980	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.019	0.981	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.019	0.981	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.019	0.981	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.981	0.019
H03 Disorders of eyelid in diseases classified elsewhere	0.018	0.982	0.000
C34.2 Middle lobe, bronchus or lung	0.018	0.982	0.000
H83.3 Noise effects on inner ear	0.018	0.982	0.000
H05 Disorders of orbit	0.017	0.983	0.000
H83.8 Other specified diseases of inner ear	0.017	0.983	0.000
E10.3 With ophthalmic complications	0.016	0.984	0.000
H80.9 Otosclerosis, unspecified	0.016	0.984	0.000
H04 Disorders of lachrymal system	0.016	0.984	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.016	0.984	0.000
C34.8 Overlapping lesion of bronchus and lung	0.016	0.984	0.000
H80 Otosclerosis	0.015	0.985	0.000
H83.9 Disease of inner ear, unspecified	0.015	0.985	0.000
E10 Insulin-dependent diabetes mellitus	0.015	0.985	0.000
H80-H83 Diseases of inner ear	0.015	0.985	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.015	0.985	0.000
E10.2 With renal complications	0.015	0.985	0.000
C34.1 Upper lobe, bronchus or lung	0.015	0.985	0.000
H83.2 Labyrinthine dysfunction	0.014	0.986	0.000
H83.1 Labyrinthine fistula	0.014	0.986	0.000
E10.4 With neurological complications	0.014	0.986	0.000
H05.1 Chronic inflammatory disorders of orbit	0.013	0.987	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.013	0.987	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.013	0.987	0.000
E10.6 With other specified complications	0.013	0.987	0.000
H04.1 Other disorders of lachrymal gland	0.013	0.987	0.000
H05.9 Disorder of orbit, unspecified	0.013	0.987	0.000
H05.2 Exophthalmic conditions	0.013	0.987	0.000
H04.4 Chronic inflammation of lachrymal passages	0.012	0.987	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.012	0.987	0.000
H05.3 Deformity of orbit	0.012	0.987	0.000
E10.7 With multiple complications	0.012	0.988	0.000
H04.9 Disorder of lachrymal system, unspecified	0.012	0.988	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.012	0.988	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.012	0.988	0.000
H05.4 Enophthalmos	0.012	0.988	0.000
H04.0 Dacryoadenitis	0.012	0.988	0.000
E10.8 With unspecified complications	0.012	0.988	0.000
E10.9 Without complications	0.012	0.988	0.000
H04.6 Other changes in lachrymal passages	0.011	0.989	0.000
F20.0 Paranoid schizophrenia	0.000	0.989	0.011
H04.8 Other disorders of lachrymal system	0.011	0.989	0.000
H80.8 Other otosclerosis	0.011	0.989	0.000
H80.2 Cochlear otosclerosis	0.011	0.989	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.011	0.989	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.011	0.989	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.011	0.989	0.000
E10.5 With peripheral circulatory complications	0.011	0.989	0.000
H04.2 Epiphora	0.011	0.989	0.000
C32 Malignant neoplasm of larynx	0.011	0.989	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.010	0.990	0.000
F20.9 Schizophrenia, unspecified	0.000	0.990	0.010
Z63.7 Other stressful life events affecting family and household	0.000	0.990	0.010
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.010	0.990	0.000
N36.2 Urethral caruncle	0.010	0.990	0.000
H05.8 Other disorders of orbit	0.010	0.990	0.000
E10.0 With coma	0.010	0.990	0.000
F20 Schizophrenia	0.000	0.990	0.010
Z63.4 Disappearance and death of family member	0.000	0.990	0.010
Z63 Other problems related to primary support group, including family circumstances	0.000	0.990	0.010
C31 Malignant neoplasm of accessory sinuses	0.009	0.990	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.009	0.991	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.009	0.991	0.000
H00 Hordeolum and chalazion	0.009	0.991	0.000
C32.0 Glottis	0.009	0.991	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.009	0.991	0.000
C32.9 Larynx, unspecified	0.009	0.991	0.000
H81 Disorders of vestibular function	0.009	0.991	0.000
H05.0 Acute inflammation of orbit	0.009	0.991	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.009	0.991	0.000
Z63.0 Problems in relationship with spouse or partner	0.000	0.991	0.009
C33 Malignant neoplasm of trachea	0.008	0.992	0.000
H81.2 Vestibular neuronitis	0.008	0.992	0.000
M47.2 Other spondylosis with radiculopathy	0.008	0.992	0.000
H81.9 Disorder of vestibular function, unspecified	0.008	0.992	0.000
C32.8 Overlapping lesion of larynx	0.008	0.992	0.000
C32.3 Laryngeal cartilage	0.008	0.992	0.000
C32.2 Subglottis	0.008	0.992	0.000
N36.0 Urethral fistula	0.008	0.992	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.992	0.008
I34.1 Mitral (valve) prolapse	0.000	0.992	0.008
C31.0 Maxillary sinus	0.008	0.992	0.000
C37 Malignant neoplasm of thymus	0.007	0.992	0.000
Z63.6 Dependent relative needing care at home	0.000	0.992	0.007
C38.4 Pleura	0.007	0.993	0.000
N36 Other disorders of urethra	0.007	0.993	0.000
C32.1 Supraglottis	0.007	0.993	0.000
F20.6 Simple schizophrenia	0.000	0.993	0.007
F20.4 Postschizophrenic depression	0.000	0.993	0.007
F20.3 Undifferentiated schizophrenia	0.000	0.993	0.007
F20.1 Hebephrenic schizophrenia	0.000	0.993	0.007
F20.5 Residual schizophrenia	0.000	0.993	0.007
Z63.9 Problem related to primary support group, unspecified	0.000	0.993	0.007
Z63.3 Absence of family member	0.000	0.993	0.007
Z63.2 Inadequate family support	0.000	0.993	0.007
Z63.1 Problems in relationship with parents and in-laws	0.000	0.993	0.007
C30.0 Nasal cavity	0.007	0.993	0.000
C31.9 Accessory sinus, unspecified	0.007	0.993	0.000
C31.8 Overlapping lesion of accessory sinuses	0.007	0.993	0.000
C31.3 Sphenoidal sinus	0.007	0.993	0.000
C31.2 Frontal sinus	0.007	0.993	0.000
C31.1 Ethmoidal sinus	0.007	0.993	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.007	0.993	0.000
C38.2 Posterior mediastinum	0.007	0.993	0.000
C38.1 Anterior mediastinum	0.007	0.993	0.000
C38.0 Heart	0.007	0.993	0.000
C38.3 Mediastinum, part unspecified	0.007	0.993	0.000
C30.1 Middle ear	0.007	0.993	0.000
F20.2 Catatonic schizophrenia	0.000	0.993	0.007
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.007	0.993	0.000
Z63.5 Disruption of family by separation and divorce	0.000	0.993	0.007
C39.9 Ill-defined sites within the respiratory system	0.007	0.993	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.007	0.993	0.000
C39.0 Upper respiratory tract, part unspecified	0.007	0.993	0.000
H81.4 Vertigo of central origin	0.007	0.993	0.000
F20.8 Other schizophrenia	0.000	0.993	0.006
R61.9 Hyperhidrosis, unspecified	0.007	0.993	0.000
H81.8 Other disorders of vestibular function	0.006	0.994	0.000
E10.1 With ketoacidosis	0.006	0.994	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.006	0.994	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.006	0.994	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.006	0.994	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.006	0.994	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.006	0.994	0.000
H81.3 Other peripheral vertigo	0.006	0.994	0.000
N36.8 Other specified disorders of urethra	0.006	0.994	0.000
N36.1 Urethral diverticulum	0.006	0.994	0.000
S82.50 Fracture of medial malleolus (closed)	0.006	0.994	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.005	0.995	0.000
Z36.8 Other antenatal screening	0.000	0.995	0.005
R22.3 Localised swelling, mass and lump, upper limb	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.005
H33.0 Retinal detachment with retinal break	0.005	0.995	0.000
J80 Adult respiratory distress syndrome	0.005	0.995	0.000
H01 Other inflammation of eyelid	0.005	0.995	0.000
H81.1 Benign paroxysmal vertigo	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.995	0.005
U80.1 Methicillin resistant agent	0.005	0.995	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.005	0.995	0.000
L91.0 Keloid scar	0.005	0.995	0.000
K85.9 Acute pancreatitis, unspecified	0.005	0.995	0.000
N36.3 Prolapsed urethral mucosa	0.005	0.995	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
C51.9 Vulva, unspecified	0.004	0.995	0.000
J84 Other interstitial pulmonary diseases	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
Y60.0 During surgical operation	0.004	0.996	0.000
U80 Agent resistant to penicillin and related antibiotics	0.004	0.996	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
N36.9 Urethral disorder, unspecified	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
U80.8 Agent resistant to other penicillin-related antibiotic	0.004	0.996	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.004	0.996	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
K70.4 Alcoholic hepatic failure	0.000	0.996	0.004
D47.2 Monoclonal gammopathy	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
U80.0 Penicillin resistant agent	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.996	0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.996	0.004
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
Q82.5 Congenital nonneoplastic naevus	0.004	0.996	0.000
F22 Persistent delusional disorders	0.000	0.996	0.003
H01.1 Non-infectious dermatoses of eyelid	0.003	0.996	0.001
J84.8 Other specified interstitial pulmonary diseases	0.003	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.003
K04.8 Radicular cyst	0.003	0.997	0.000
L91.8 Other hypertrophic disorders of skin	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
J84.0 Alveolar and parietoalveolar conditions	0.003	0.997	0.000
K50.8 Other Crohn's disease	0.000	0.997	0.003
S12.1 Fracture of second cervical vertebra	0.000	0.997	0.003
L91 Hypertrophic disorders of skin	0.003	0.997	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.997	0.003
Z36 Antenatal screening	0.000	0.997	0.003
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
F28 Other nonorganic psychotic disorders	0.000	0.997	0.003
F24 Induced delusional disorder	0.000	0.997	0.003
F21 Schizotypal disorder	0.000	0.997	0.003
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
F29 Unspecified nonorganic psychosis	0.000	0.997	0.003
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
F22.0 Delusional disorder	0.000	0.997	0.003
H18.4 Corneal degeneration	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.003	0.997	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.997	0.003
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
F22.8 Other persistent delusional disorders	0.000	0.997	0.003
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.997	0.003
S12 Fracture of neck	0.000	0.997	0.003
F23 Acute and transient psychotic disorders	0.000	0.997	0.003
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.997	0.003
S12.9 Fracture of neck, part unspecified	0.000	0.997	0.003
H01.9 Inflammation of eyelid, unspecified	0.002	0.997	0.001
H66.9 Otitis media, unspecified	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
S12.2 Fracture of other specified cervical vertebra	0.000	0.997	0.003
S12.11 Fracture of second cervical vertebra (open)	0.000	0.997	0.003
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
H01.8 Other specified inflammation of eyelid	0.002	0.997	0.001
R63.0 Anorexia	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.000	0.997	0.003
H66.0 Acute suppurative otitis media	0.002	0.997	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.997	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.997	0.000
H70 Mastoiditis and related conditions	0.002	0.997	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.997	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.997	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.002
Y60.9 During unspecified surgical and medical care	0.002	0.997	0.000
Y60.8 During other surgical and medical care	0.002	0.997	0.000
Y60.7 During administration of enema	0.002	0.997	0.000
Y60.3 During injection or immunisation	0.002	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.002	0.997	0.000
Y60.1 During infusion or transfusion	0.002	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
L91.9 Hypertrophic disorder of skin, unspecified	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
K85 Acute pancreatitis	0.002	0.998	0.000
R61 Hyperhidrosis	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
K70 Alcoholic liver disease	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.998	0.002
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
Y60.5 During heart catheterisation	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.000	0.998	0.002
R63.5 Abnormal weight gain	0.000	0.998	0.002
S12.0 Fracture of first cervical vertebra	0.000	0.998	0.002
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.998	0.002
S12.8 Fracture of other parts of neck	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.998	0.002
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.998	0.002
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
S12.91 Fracture of neck, part unspecified (open)	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.998	0.002
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.998	0.002
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
F25 Schizoaffective disorders	0.000	0.998	0.002
H70.1 Chronic mastoiditis	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
C51.0 Labium majus	0.002	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
Z98.1 Arthrodesis status	0.002	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
R61.1 Generalised hyperhidrosis	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
K85.8 Other acute pancreatitis	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
S12.01 Fracture of first cervical vertebra (open)	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.000	0.998	0.002
C51.8 Overlapping lesion of vulva	0.002	0.998	0.000
C51.2 Clitoris	0.002	0.998	0.000
C51.1 Labium minus	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
S12.81 Fracture of other parts of neck (open)	0.000	0.998	0.002
S12.80 Fracture of other parts of neck (closed)	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
E28 Ovarian dysfunction	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
H01.0 Blepharitis	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
X60.8 Other specified place	0.000	0.998	0.002
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.002	0.998	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.002	0.998	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.002	0.998	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.002	0.998	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.002	0.998	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.002	0.998	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.002	0.998	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.002	0.998	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.002	0.998	0.000
S05.8 Other injuries of eye and orbit	0.000	0.998	0.002
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.000	0.998	0.002
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.998	0.002
Q82 Other congenital malformations of skin	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.998	0.002
S91.0 Open wound of ankle	0.002	0.998	0.000
N63 Unspecified lump in breast	0.002	0.998	0.000
R61.0 Localised hyperhidrosis	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
J43.9 Emphysema, unspecified	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H68.0 Eustachian salpingitis	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
R46.2 Strange and inexplicable behaviour	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
F10.4 Withdrawal state with delirium	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
S92.7 Multiple fractures of foot	0.001	0.998	0.000
X60.2 School, other institution and public administrative area	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.000	0.998	0.001
H69.0 Patulous Eustachian tube	0.001	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
X68.9 Unspecified place	0.000	0.998	0.002
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.000	0.998	0.002
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.001
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.998	0.001
H92.0 Otalgia	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
M79.18 Myalgia (Other)	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
R46.4 Slowness and poor responsiveness	0.000	0.998	0.001
R46 Symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
H65.4 Other chronic nonsuppurative otitis media	0.001	0.998	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.002	0.998	0.000
S92.4 Fracture of great toe	0.001	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.998	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.001
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.999	0.001
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.001	0.999	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.999	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.000	0.999	0.001
Z58 Problems related to physical environment	0.000	0.999	0.001
H60-H62 Diseases of external ear	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.999	0.000
C92 Myeloid leukaemia	0.001	0.999	0.000
Z89 Acquired absence of limb	0.001	0.999	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.999	0.001
K04.4 Acute apical periodontitis of pulpal origin	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.999	0.000
U50 Level of care administered to neonates	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations