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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77662038
log Bayes Factor = 13.6756
Chromosome 12   position 83,497,229  (GRCh37) Explore rs77662038 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
B95-B98 Bacterial, viral and other infectious agents
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
M05-M14 Inflammatory polyarthropathies
0.979 0.021 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
Chapter IX Diseases of the circulatory system
0.965 0.035 0.000
M06 Other rheumatoid arthritis
0.964 0.036 0.000
R50-R69 General symptoms and signs
0.963 0.037 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.963 0.037 0.000
M70-M79 Other soft tissue disorders
0.959 0.041 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.953 0.047 0.000
D00-D09 In situ neoplasms
0.952 0.048 0.000
F30-F39 Mood [affective] disorders
0.952 0.048 0.000
R50 Fever of unknown origin
0.949 0.051 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.943 0.057 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.943 0.057 0.000
M06.9 Rheumatoid arthritis, unspecified
0.942 0.058 0.000
Chapter XX External causes of morbidity and mortality
0.942 0.058 0.000
R50.9 Fever, unspecified
0.940 0.060 0.000
M20-M25 Other joint disorders
0.937 0.063 0.000
I10-I15 Hypertensive diseases
0.936 0.064 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.936 0.064 0.000
G62 Other polyneuropathies
0.936 0.064 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.934 0.066 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.932 0.068 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.928 0.072 0.000
R63 Symptoms and signs concerning food and fluid intake
0.927 0.073 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.923 0.077 0.000
F31 Bipolar affective disorder
0.923 0.077 0.000
T81 Complications of procedures, not elsewhere classified
0.921 0.079 0.000
A00-A09 Intestinal infectious diseases
0.919 0.081 0.000
C51-C58 Malignant neoplasms of female genital organs
0.913 0.087 0.000
M23 Internal derangement of knee
0.906 0.094 0.000
G62.9 Polyneuropathy, unspecified
0.905 0.095 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.903 0.097 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.901 0.099 0.000
I12 Hypertensive renal disease
0.900 0.100 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.899 0.101 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.898 0.102 0.000
M50-M54 Other dorsopathies
0.898 0.102 0.000
Chapter VII Diseases of the eye and adnexa
0.897 0.103 0.000
F31.9 Bipolar affective disorder, unspecified
0.896 0.104 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.890 0.110 0.000
G40-G47 Episodic and paroxysmal disorders
0.888 0.112 0.000
S70-S79 Injuries to the hip and thigh
0.886 0.114 0.000
M80-M85 Disorders of bone density and structure
0.884 0.116 0.000
M79.6 Pain in limb
0.881 0.119 0.000
Chapter VIII Diseases of the ear and mastoid process
0.877 0.123 0.000
R26 Abnormalities of gait and mobility
0.875 0.125 0.000
D05 Carcinoma in situ of breast
0.875 0.125 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.875 0.125 0.000
M65-M68 Disorders of synovium and tendon
0.874 0.126 0.000
G90-G99 Other disorders of the nervous system
0.874 0.126 0.000
G30-G32 Other degenerative diseases of the nervous system
0.872 0.128 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.870 0.130 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.869 0.131 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.868 0.132 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.866 0.134 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.863 0.137 0.000
G40 Epilepsy
0.861 0.139 0.000
F03 Unspecified dementia
0.857 0.143 0.000
G81 Hemiplegia
0.857 0.143 0.000
I80 Phlebitis and thrombophlebitis
0.857 0.143 0.000
S90-S99 Injuries to the ankle and foot
0.852 0.148 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.852 0.148 0.000
O00-O08 Pregnancy with abortive outcome
0.850 0.150 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.846 0.154 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.843 0.157 0.000
G40.9 Epilepsy, unspecified
0.838 0.162 0.000
M79.8 Other specified soft tissue disorders
0.837 0.163 0.000
H90-H95 Other disorders of ear
0.837 0.163 0.000
M45-M49 Spondylopathies
0.836 0.164 0.000
I12.0 Hypertensive renal disease with renal failure
0.836 0.164 0.000
M06.0 Seronegative rheumatoid arthritis
0.835 0.165 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.834 0.166 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.833 0.167 0.000
M86-M90 Other osteopathies
0.831 0.169 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.830 0.170 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.824 0.176 0.000
W00-W19 Falls
0.822 0.178 0.000
R52 Pain, not elsewhere classified
0.820 0.180 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.820 0.180 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.819 0.181 0.000
C56 Malignant neoplasm of ovary
0.818 0.182 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.816 0.184 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.814 0.186 0.000
M81 Osteoporosis without pathological fracture
0.813 0.187 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.813 0.187 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.813 0.187 0.000
R63.0 Anorexia
0.811 0.189 0.000
H53-H54 Visual disturbances and blindness
0.807 0.193 0.000
G81.9 Hemiplegia, unspecified
0.806 0.194 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.806 0.194 0.000
F00 Dementia in Alzheimer's disease
0.805 0.195 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.804 0.196 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.802 0.198 0.000
X60-X84 Intentional self-harm
0.801 0.199 0.000
I12.9 Hypertensive renal disease without renal failure
0.798 0.202 0.000
Chapter XXII Codes for special purposes
0.797 0.203 0.000
A04 Other bacterial intestinal infections
0.795 0.205 0.000
M23.3 Other meniscus derangements
0.795 0.205 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.794 0.206 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.794 0.206 0.000
R68 Other general symptoms and signs
0.793 0.206 0.000
O04 Medical abortion
0.793 0.207 0.000
I95 Hypotension
0.792 0.208 0.000
M40-M43 Deforming dorsopathies
0.791 0.209 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.790 0.210 0.000
C71 Malignant neoplasm of brain
0.788 0.212 0.000
D04 Carcinoma in situ of skin
0.785 0.215 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
I10 Essential (primary) hypertension
0.784 0.216 0.000
M79.7 Fibromyalgia
0.782 0.218 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.780 0.220 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.779 0.221 0.000
S50-S59 Injuries to the elbow and forearm
0.778 0.222 0.000
M50 Cervical disk disorders
0.776 0.224 0.000
B15-B19 Viral hepatitis
0.774 0.226 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.773 0.227 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.773 0.227 0.000
R57 Shock, not elsewhere classified
0.772 0.228 0.000
Chapter X Diseases of the respiratory system
0.772 0.228 0.000
G30 Alzheimer's disease
0.771 0.229 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.771 0.229 0.000
T66-T78 Other and unspecified effects of external causes
0.770 0.230 0.000
G62.8 Other specified polyneuropathies
0.768 0.232 0.000
R55 Syncope and collapse
0.767 0.233 0.000
R47-R49 Symptoms and signs involving speech and voice
0.767 0.233 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.766 0.234 0.000
S80-S89 Injuries to the knee and lower leg
0.766 0.234 0.000
M81.9 Osteoporosis, unspecified
0.762 0.238 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.761 0.239 0.000
R63.4 Abnormal weight loss
0.760 0.240 0.000
R60 Oedema, not elsewhere classified
0.760 0.240 0.000
G20-G26 Extrapyramidal and movement disorders
0.759 0.241 0.000
D05.1 Intraductal carcinoma in situ
0.759 0.241 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.759 0.241 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.757 0.243 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.757 0.243 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.757 0.243 0.000
G70-G73 Diseases of myoneural junction and muscle
0.756 0.244 0.000
S60-S69 Injuries to the wrist and hand
0.755 0.245 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.754 0.246 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.753 0.247 0.000
O04.9 Complete or unspecified, without complication
0.752 0.248 0.000
S20-S29 Injuries to the thorax
0.751 0.248 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.750 0.250 0.000
M91-M94 Chondropathies
0.750 0.250 0.000
S70 Superficial injury of hip and thigh
0.750 0.250 0.000
H54 Blindness and low vision
0.750 0.250 0.000
D03 Melanoma in situ
0.748 0.252 0.000
M24 Other specific joint derangements
0.748 0.252 0.000
D09 Carcinoma in situ of other and unspecified sites
0.745 0.255 0.000
F60-F69 Disorders of adult personality and behaviour
0.743 0.257 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.743 0.257 0.000
S40-S49 Injuries to the shoulder and upper arm
0.742 0.258 0.000
M79.0 Rheumatism, unspecified
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
G80 Infantile cerebral palsy
0.741 0.259 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.739 0.261 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.738 0.262 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.738 0.262 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.737 0.263 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.737 0.263 0.000
F33 Recurrent depressive disorder
0.737 0.263 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.264 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.736 0.264 0.000
M05 Seropositive rheumatoid arthritis
0.733 0.266 0.000
R54 Senility
0.732 0.268 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.732 0.268 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.730 0.270 0.000
M65 Synovitis and tenosynovitis
0.730 0.270 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.727 0.273 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.727 0.273 0.000
C92 Myeloid leukaemia
0.726 0.274 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.726 0.274 0.000
G93 Other disorders of brain
0.726 0.274 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.725 0.275 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.725 0.275 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.725 0.275 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.724 0.276 0.000
M72 Fibroblastic disorders
0.724 0.276 0.000
R52.9 Pain, unspecified
0.723 0.277 0.000
M25 Other joint disorders, not elsewhere classified
0.723 0.277 0.000
I95.2 Hypotension due to drugs
0.723 0.277 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.721 0.279 0.000
C53 Malignant neoplasm of cervix uteri
0.721 0.279 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.721 0.279 0.000
M31 Other necrotising vasculopathies
0.721 0.279 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.721 0.279 0.000
M67 Other disorders of synovium and tendon
0.720 0.280 0.000
M23.4 Loose body in knee
0.718 0.282 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
H91 Other hearing loss
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S79 Other and unspecified injuries of hip and thigh
0.716 0.284 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
W20-W49 Exposure to inanimate mechanical forces
0.715 0.285 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.285 0.000
O03 Spontaneous abortion
0.714 0.286 0.000
H25-H28 Disorders of lens
0.714 0.286 0.000
M07 Psoriatic and enteropathic arthropathies
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.712 0.288 0.000
H93 Other disorders of ear, not elsewhere classified
0.712 0.288 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.712 0.288 0.000
Q50-Q56 Congenital malformations of genital organs
0.711 0.288 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.711 0.289 0.000
M79.69 Pain in limb (Site unspecified)
0.710 0.290 0.000
I05-I09 Chronic rheumatic heart diseases
0.710 0.290 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.708 0.292 0.000
H43-H45 Disorders of vitreous body and globe
0.708 0.292 0.000
G61 Inflammatory polyneuropathy
0.706 0.293 0.000
M10 Gout
0.706 0.293 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
C78.2 Secondary malignant neoplasm of pleura
0.705 0.295 0.000
C80 Malignant neoplasm without specification of site
0.705 0.295 0.000
M77 Other enthesopathies
0.704 0.296 0.000
M71 Other bursopathies
0.702 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.702 0.298 0.000
T86 Failure and rejection of transplanted organs and tissues
0.702 0.298 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.702 0.298 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
M12 Other specific arthropathies
0.702 0.298 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
C79 Secondary malignant neoplasm of other sites
0.701 0.298 0.000
S92 Fracture of foot, except ankle
0.701 0.299 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.701 0.299 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.701 0.299 0.000
D46 Myelodysplastic syndromes
0.700 0.300 0.000
M21 Other acquired deformities of limbs
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.699 0.300 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.699 0.301 0.000
G30.9 Alzheimer's disease, unspecified
0.699 0.301 0.000
I95.9 Hypotension, unspecified
0.699 0.301 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
D10-D36 Benign neoplasms
0.699 0.301 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.698 0.302 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.698 0.302 0.000
T79-T79 Certain early complications of trauma
0.697 0.303 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.697 0.303 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.697 0.303 0.000
R27 Other lack of coordination
0.697 0.303 0.000
M79.62 Pain in limb (Upper arm)
0.696 0.303 0.000
Q43 Other congenital malformations of intestine
0.696 0.304 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.695 0.305 0.000
M79.60 Pain in limb (Multiple sites)
0.694 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.306 0.000
C54 Malignant neoplasm of corpus uteri
0.692 0.308 0.000
I00-I02 Acute rheumatic fever
0.692 0.308 0.000
G95 Other diseases of spinal cord
0.692 0.308 0.000
M06.8 Other specified rheumatoid arthritis
0.691 0.309 0.000
M06.4 Inflammatory polyarthropathy
0.691 0.309 0.000
M06.3 Rheumatoid nodule
0.691 0.309 0.000
M06.2 Rheumatoid bursitis
0.691 0.309 0.000
M06.1 Adult-onset Still's disease
0.691 0.309 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.691 0.309 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.690 0.309 0.000
R62 Lack of expected normal physiological development
0.690 0.309 0.000
R64 Cachexia
0.690 0.309 0.000
R58 Haemorrhage, not elsewhere classified
0.690 0.309 0.000
X78 Intentional self-harm by sharp object
0.690 0.310 0.000
G60 Hereditary and idiopathic neuropathy
0.690 0.310 0.000
G64 Other disorders of peripheral nervous system
0.690 0.310 0.000
A30-A49 Other bacterial diseases
0.690 0.310 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.689 0.311 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.689 0.311 0.000
Y52 Agents primarily affecting the cardiovascular system
0.688 0.312 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.688 0.312 0.000
M23.5 Chronic instability of knee
0.688 0.312 0.000
M76 Enthesopathies of lower limb, excluding foot
0.688 0.312 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.312 0.000
M13 Other arthritis
0.687 0.313 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.686 0.313 0.000
R56 Convulsions, not elsewhere classified
0.686 0.314 0.000
T17 Foreign body in respiratory tract
0.685 0.315 0.000
H90 Conductive and sensorineural hearing loss
0.684 0.315 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.684 0.316 0.000
S99 Other and unspecified injuries of ankle and foot
0.684 0.316 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.683 0.317 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.683 0.317 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.683 0.317 0.000
F38 Other mood [affective] disorders
0.682 0.317 0.000
F34 Persistent mood [affective] disorders
0.682 0.317 0.000
F30 Manic episode
0.682 0.317 0.000
F39 Unspecified mood [affective] disorder
0.682 0.317 0.000
M87 Osteonecrosis
0.682 0.318 0.000
I87 Other disorders of veins
0.682 0.318 0.000
M54 Dorsalgia
0.682 0.318 0.000
R50.8 Other specified fever
0.680 0.319 0.000
R50.2 Drug-induced fever
0.680 0.319 0.000
R50.1 Persistent fever
0.680 0.319 0.000
M79.9 Soft tissue disorder, unspecified
0.676 0.324 0.000
M79.5 Residual foreign body in soft tissue
0.676 0.324 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.676 0.324 0.000
M79.3 Panniculitis, unspecified
0.676 0.324 0.000
M79.2 Neuralgia and neuritis, unspecified
0.676 0.324 0.000
M79.1 Myalgia
0.676 0.324 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.676 0.324 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.675 0.325 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.675 0.325 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.675 0.325 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.675 0.325 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.675 0.325 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.675 0.325 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.675 0.325 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.675 0.325 0.000
Y35-Y36 Legal intervention and operations of war
0.675 0.325 0.000
Y10-Y34 Event of undetermined intent
0.675 0.325 0.000
Y00-Y09 Assault
0.675 0.325 0.000
X85-X99 Assault
0.675 0.325 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.675 0.325 0.000
X50-X57 Overexertion, travel and privation
0.675 0.325 0.000
X30-X39 Exposure to forces of nature
0.675 0.325 0.000
X20-X29 Contact with venomous animals and plants
0.675 0.325 0.000
X10-X19 Contact with heat and hot substances
0.675 0.325 0.000
X00-X09 Exposure to smoke, fire and flames
0.675 0.325 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.675 0.325 0.000
W75-W84 Other accidental threats to breathing
0.675 0.325 0.000
W65-W74 Accidental drowning and submersion
0.675 0.325 0.000
W50-W64 Exposure to animate mechanical forces
0.675 0.325 0.000
V98-V99 Other and unspecified transport accidents
0.675 0.325 0.000
V95-V97 Air and space transport accidents
0.675 0.325 0.000
V90-V94 Water transport accidents
0.675 0.325 0.000
V70-V79 Bus occupant injured in transport accident
0.675 0.325 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.675 0.325 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.675 0.325 0.000
V40-V49 Car occupant injured in transport accident
0.675 0.325 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.675 0.325 0.000
V01-V09 Pedestrian injured in transport accident
0.675 0.325 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.672 0.328 0.000
M34 Systemic sclerosis
0.672 0.328 0.000
M33 Dermatopolymyositis
0.672 0.328 0.000
M32 Systemic lupus erythematosus
0.672 0.328 0.000
M30 Polyarteritis nodosa and related conditions
0.672 0.328 0.000
I15 Secondary hypertension
0.671 0.329 0.000
I13 Hypertensive heart and renal disease
0.671 0.329 0.000
I11 Hypertensive heart disease
0.671 0.329 0.000
R50.0 Fever with chills
0.671 0.329 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.671 0.329 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.671 0.329 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.671 0.329 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.671 0.329 0.000
G62.2 Polyneuropathy due to other toxic agents
0.671 0.329 0.000
G62.1 Alcoholic polyneuropathy
0.671 0.329 0.000
G62.0 Drug-induced polyneuropathy
0.671 0.329 0.000
C71.9 Brain, unspecified
0.671 0.329 0.000
H10-H13 Disorders of conjunctiva
0.671 0.329 0.000
F22 Persistent delusional disorders
0.670 0.330 0.000
O16 Unspecified maternal hypertension
0.670 0.330 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.669 0.331 0.000
W07 Fall involving chair
0.669 0.331 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.668 0.332 0.000
F02 Dementia in other diseases classified elsewhere
0.668 0.332 0.000
F01 Vascular dementia
0.668 0.332 0.000
F09 Unspecified organic or symptomatic mental disorder
0.668 0.332 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.668 0.332 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.667 0.333 0.000
H40-H42 Glaucoma
0.667 0.333 0.000
M51 Other intervertebral disk disorders
0.667 0.333 0.000
M79.79 Fibromyalgia (Site unspecified)
0.666 0.334 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.666 0.334 0.000
S72 Fracture of femur
0.666 0.334 0.000
H92 Otalgia and effusion of ear
0.666 0.334 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.666 0.334 0.000
G83 Other paralytic syndromes
0.665 0.334 0.000
G82 Paraplegia and tetraplegia
0.665 0.334 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.665 0.335 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.665 0.335 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.664 0.335 0.000
R63.5 Abnormal weight gain
0.664 0.335 0.000
R63.3 Feeding difficulties and mismanagement
0.664 0.335 0.000
R63.2 Polyphagia
0.664 0.335 0.000
R63.1 Polydipsia
0.664 0.335 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.664 0.336 0.000
R29.6 Tendency to fall, not elsewhere classified
0.663 0.337 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.662 0.338 0.000
F31.8 Other bipolar affective disorders
0.662 0.338 0.000
F31.7 Bipolar affective disorder, currently in remission
0.662 0.338 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.662 0.338 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.662 0.338 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.662 0.338 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.662 0.338 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.662 0.338 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.662 0.338 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.661 0.338 0.000
M11 Other crystal arthropathies
0.661 0.339 0.000
I78 Diseases of capillaries
0.661 0.339 0.000
B35-B49 Mycoses
0.661 0.339 0.000
R26.3 Immobility
0.660 0.340 0.000
D06 Carcinoma in situ of cervix uteri
0.660 0.340 0.000
T81.9 Unspecified complication of procedure
0.660 0.340 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.660 0.340 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.660 0.340 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.660 0.340 0.000
A07 Other protozoal intestinal diseases
0.659 0.341 0.000
A06 Amoebiasis
0.659 0.341 0.000
A05 Other bacterial foodborne intoxications
0.659 0.341 0.000
A03 Shigellosis
0.659 0.341 0.000
A02 Other Salmonella infections
0.659 0.341 0.000
A01 Typhoid and paratyphoid fevers
0.659 0.341 0.000
A00 Cholera
0.659 0.341 0.000
F23 Acute and transient psychotic disorders
0.658 0.342 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.658 0.342 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.657 0.343 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.656 0.344 0.000
I72 Other aneurysm
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.654 0.345 0.000
C51 Malignant neoplasm of vulva
0.654 0.345 0.000
C58 Malignant neoplasm of placenta
0.654 0.345 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.654 0.345 0.000
C52 Malignant neoplasm of vagina
0.654 0.345 0.000
F41 Other anxiety disorders
0.654 0.346 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.654 0.346 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.653 0.347 0.000
F29 Unspecified nonorganic psychosis
0.653 0.347 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.653 0.347 0.000
M46 Other inflammatory spondylopathies
0.652 0.347 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.652 0.348 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.652 0.348 0.000
J90-J94 Other diseases of pleura
0.652 0.348 0.000
S82 Fracture of lower leg, including ankle
0.652 0.348 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.650 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.650 0.350 0.000
M23.9 Internal derangement of knee, unspecified
0.650 0.350 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.650 0.350 0.000
M23.1 Discoid meniscus (congenital)
0.650 0.350 0.000
M23.0 Cystic meniscus
0.650 0.350 0.000
I99 Other and unspecified disorders of circulatory system
0.650 0.350 0.000
M48 Other spondylopathies
0.649 0.351 0.000
A04.8 Other specified bacterial intestinal infections
0.649 0.351 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.648 0.352 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.648 0.352 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.648 0.352 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.648 0.352 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.648 0.352 0.000
A08 Viral and other specified intestinal infections
0.647 0.353 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.646 0.353 0.000
O85-O92 Complications predominantly related to the puerperium
0.646 0.354 0.000
M79.67 Pain in limb (Ankle and foot)
0.646 0.354 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.644 0.356 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.644 0.356 0.000
Q80-Q89 Other congenital malformations
0.644 0.356 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.644 0.356 0.000
Q60-Q64 Congenital malformations of the urinary system
0.644 0.356 0.000
Q35-Q37 Cleft lip and cleft palate
0.644 0.356 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.356 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.642 0.358 0.000
W10 Fall on and from stairs and steps
0.642 0.358 0.000
M79.64 Pain in limb (Hand)
0.641 0.359 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.640 0.359 0.000
Y57 Other and unspecified drugs and medicaments
0.640 0.360 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.640 0.360 0.000
D04.6 Skin of upper limb, including shoulder
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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