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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7770592
log Bayes Factor = 38.6096
Chromosome 6   position 29,395,747  (GRCh37) Explore rs7770592 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.008 0.992
E10.9 Without complications
0.000 0.012 0.988
E10.2 With renal complications
0.000 0.033 0.967
E10.1 With ketoacidosis
0.000 0.047 0.953
E10-E14 Diabetes mellitus
0.000 0.050 0.950
E13 Other specified diabetes mellitus
0.000 0.072 0.928
E13.9 Without complications
0.000 0.087 0.913
E10.4 With neurological complications
0.000 0.089 0.911
E10.0 With coma
0.000 0.203 0.797
E14 Unspecified diabetes mellitus
0.000 0.242 0.758
E10.6 With other specified complications
0.000 0.248 0.752
E10.5 With peripheral circulatory complications
0.000 0.257 0.743
E10.7 With multiple complications
0.000 0.277 0.723
E12 Malnutrition-related diabetes mellitus
0.000 0.319 0.681
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.320 0.680
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.326 0.674
E16 Other disorders of pancreatic internal secretion
0.000 0.330 0.670
E16.2 Hypoglycaemia, unspecified
0.000 0.334 0.666
E13.8 With unspecified complications
0.000 0.334 0.665
E13.7 With multiple complications
0.000 0.334 0.665
E13.6 With other specified complications
0.000 0.334 0.665
E13.5 With peripheral circulatory complications
0.000 0.334 0.665
E13.4 With neurological complications
0.000 0.334 0.665
E13.2 With renal complications
0.000 0.334 0.665
E13.1 With ketoacidosis
0.000 0.334 0.665
E13.0 With coma
0.000 0.334 0.665
E13.3 With ophthalmic complications
0.000 0.338 0.662
E00-E07 Disorders of thyroid gland
0.000 0.361 0.639
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.365 0.635
E05.9 Thyrotoxicosis, unspecified
0.000 0.372 0.628
E14.9 Without complications
0.000 0.384 0.616
E14.2 Withrenal complications
0.000 0.411 0.589
E14.4 With neurological complications
0.000 0.427 0.573
E16.1 Other hypoglycaemia
0.000 0.431 0.569
E14.8 With unspecified complications
0.000 0.445 0.555
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.447 0.553
E14.7 With multiple complications
0.000 0.456 0.544
E14.6 With other specified complications
0.000 0.456 0.544
E14.5 With peripheral circulatory complications
0.000 0.456 0.544
E14.0 With coma
0.000 0.456 0.544
E14.1 With ketoacidosis
0.000 0.457 0.543
E05.8 Other thyrotoxicosis
0.000 0.458 0.542
E10.8 With unspecified complications
0.000 0.469 0.530
K51 Ulcerative colitis
0.513 0.487 0.000
K51.9 Ulcerative colitis, unspecified
0.502 0.498 0.000
K90 Intestinal malabsorption
0.000 0.503 0.497
K51.4 Pseudopolyposis of colon
0.497 0.503 0.000
K51.2 Ulcerative (chronic) proctitis
0.492 0.508 0.000
E12.9 Without complications
0.000 0.511 0.488
E12.8 With unspecified complications
0.000 0.511 0.488
E12.7 With multiple complications
0.000 0.511 0.488
E12.6 With other specified complications
0.000 0.511 0.488
E12.5 With peripheral circulatory complications
0.000 0.511 0.488
E12.4 With neurological complications
0.000 0.511 0.488
E12.3 With ophthalmic complications
0.000 0.511 0.488
E12.2 With renal complications
0.000 0.511 0.488
E12.1 With ketoacidosis
0.000 0.511 0.488
E12.0 With coma
0.000 0.511 0.488
E15 Nondiabetic hypoglycaemic coma
0.000 0.517 0.483
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.519 0.481
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.519 0.481
E16.4 Abnormal secretion of gastrin
0.000 0.519 0.481
E16.3 Increased secretion of glucagon
0.000 0.519 0.481
K51.3 Ulcerative (chronic) rectosigmoiditis
0.480 0.520 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.525 0.475
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.542 0.458
E00 Congenital iodine-deficiency syndrome
0.000 0.542 0.458
E05.5 Thyroid crisis or storm
0.000 0.544 0.456
E05.4 Thyrotoxicosis factitia
0.000 0.544 0.456
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.544 0.456
E40-E46 Malnutrition
0.000 0.555 0.445
K51.0 Ulcerative (chronic) enterocolitis
0.436 0.564 0.000
E14.3 With ophthalmic complications
0.000 0.564 0.436
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.564 0.436
E07 Other disorders of thyroid
0.000 0.576 0.424
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.604 0.396
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.611 0.389
K51.1 Ulcerative (chronic) ileocolitis
0.379 0.621 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.627 0.373
E11 Non-insulin-dependent diabetes mellitus
0.000 0.628 0.372
K51.5 Mucosal proctocolitis
0.371 0.629 0.000
K51.8 Other ulcerative colitis
0.367 0.633 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.643 0.357
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.643 0.357
K90.1 Tropical sprue
0.000 0.643 0.357
K90.9 Intestinal malabsorption, unspecified
0.000 0.644 0.356
E04 Other non-toxic goitre
0.000 0.649 0.351
K90.8 Other intestinal malabsorption
0.000 0.653 0.347
E20-E35 Disorders of other endocrine glands
0.000 0.655 0.345
E03 Other hypothyroidism
0.000 0.657 0.343
E04.9 Non-toxic goitre, unspecified
0.000 0.659 0.341
E07.8 Other specified disorders of thyroid
0.000 0.666 0.334
E11.2 With renal complications
0.000 0.667 0.333
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.671 0.329
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.671 0.329
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.671 0.329
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.671 0.329
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.671 0.329
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.671 0.329
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.671 0.329
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.671 0.329
E06 Thyroiditis
0.000 0.675 0.325
E50-E64 Other nutritional deficiencies
0.000 0.678 0.322
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.681 0.319
E45 Retarded development following protein-energy malnutrition
0.000 0.681 0.319
E43 Unspecified severe protein-energy malnutrition
0.000 0.681 0.319
E42 Marasmic kwashiorkor
0.000 0.681 0.319
E41 Nutritional marasmus
0.000 0.681 0.319
E40 Kwashiorkor
0.000 0.681 0.319
E11.0 With coma
0.000 0.689 0.311
E23 Hypofunction and other disorders of pituitary gland
0.000 0.691 0.309
E07.1 Dyshormogenetic goitre
0.000 0.696 0.304
E07.0 Hypersecretion of calcitonin
0.000 0.696 0.304
E11.6 With other specified complications
0.000 0.699 0.301
E20 Hypoparathyroidism
0.000 0.715 0.285
E24 Cushing's syndrome
0.000 0.716 0.284
E46 Unspecified protein-energy malnutrition
0.000 0.724 0.276
E23.0 Hypopituitarism
0.000 0.726 0.274
E03.8 Other specified hypothyroidism
0.000 0.728 0.272
E23.2 Diabetes insipidus
0.000 0.731 0.269
E11.7 With multiple complications
0.000 0.733 0.267
E03.1 Congenital hypothyroidism without goitre
0.000 0.740 0.259
E06.9 Thyroiditis, unspecified
0.000 0.742 0.258
E51 Thiamine deficiency
0.000 0.747 0.252
E04.8 Other specified non-toxic goitre
0.000 0.748 0.252
E29 Testicular dysfunction
0.000 0.752 0.248
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.752 0.248
E32 Diseases of thymus
0.000 0.752 0.248
E30 Disorders of puberty, not elsewhere classified
0.000 0.752 0.248
E25 Adrenogenital disorders
0.000 0.752 0.248
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.753 0.247
E03.5 Myxoedema coma
0.000 0.754 0.246
E03.4 Atrophy of thyroid (acquired)
0.000 0.754 0.246
E03.3 Postinfectious hypothyroidism
0.000 0.754 0.246
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.754 0.246
E20.9 Hypoparathyroidism, unspecified
0.000 0.759 0.241
E56 Other vitamin deficiencies
0.000 0.759 0.241
E11.1 With ketoacidosis
0.000 0.762 0.238
E24.9 Cushing's syndrome, unspecified
0.000 0.765 0.235
E06.4 Drug-induced thyroiditis
0.000 0.767 0.233
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.767 0.233
E06.1 Subacute thyroiditis
0.000 0.767 0.233
E06.0 Acute thyroiditis
0.000 0.767 0.233
E65-E68 Obesity and other hyperalimentation
0.000 0.768 0.232
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.769 0.231
E63 Other nutritional deficiencies
0.000 0.769 0.231
E50 Vitamin A deficiency
0.000 0.769 0.231
E60 Dietary zinc deficiency
0.000 0.769 0.231
E59 Dietary selenium deficiency
0.000 0.769 0.231
E54 Ascorbic acid deficiency
0.000 0.769 0.231
E52 Niacin deficiency [pellagra]
0.000 0.769 0.231
E22 Hyperfunction of pituitary gland
0.000 0.770 0.230
E11.5 With peripheral circulatory complications
0.000 0.771 0.229
E44.1 Mild protein-energy malnutrition
0.000 0.771 0.229
E44.0 Moderate protein-energy malnutrition
0.000 0.771 0.229
E11.4 With neurological complications
0.000 0.771 0.229
E31 Polyglandular dysfunction
0.000 0.774 0.226
E28 Ovarian dysfunction
0.000 0.775 0.225
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.778 0.222
E23.1 Drug-induced hypopituitarism
0.000 0.778 0.222
E11.8 With unspecified complications
0.000 0.779 0.221
E07.9 Disorder of thyroid, unspecified
0.000 0.780 0.220
E24.2 Drug-induced Cushing's syndrome
0.000 0.787 0.213
E58 Dietary calcium deficiency
0.000 0.793 0.207
E83 Disorders of mineral metabolism
0.207 0.793 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.795 0.205
E20.8 Other hypoparathyroidism
0.000 0.796 0.204
E20.1 Pseudohypoparathyroidism
0.000 0.796 0.204
E20.0 Idiopathic hypoparathyroidism
0.000 0.796 0.204
E53 Deficiency of other B group vitamins
0.000 0.796 0.204
E24.8 Other Cushing's syndrome
0.000 0.796 0.204
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.796 0.204
E24.3 Ectopic ACTH syndrome
0.000 0.796 0.204
E24.1 Nelson's syndrome
0.000 0.796 0.204
E24.0 Pituitary-dependent Cushing's disease
0.000 0.796 0.204
E26 Hyperaldosteronism
0.000 0.797 0.203
E51.2 Wernicke's encephalopathy
0.000 0.797 0.202
E55 Vitamin D deficiency
0.000 0.805 0.195
E23.6 Other disorders of pituitary gland
0.000 0.808 0.192
E34 Other endocrine disorders
0.000 0.810 0.190
E06.5 Other chronic thyroiditis
0.000 0.812 0.187
E56.1 Deficiency of vitamin K
0.000 0.818 0.182
E51.9 Thiamine deficiency, unspecified
0.000 0.819 0.181
E51.8 Other manifestations of thiamine deficiency
0.000 0.819 0.181
E51.1 Beriberi
0.000 0.819 0.181
E22.0 Acromegaly and pituitary gigantism
0.000 0.820 0.180
E29.1 Testicular hypofunction
0.000 0.821 0.179
E29.9 Testicular dysfunction, unspecified
0.000 0.822 0.178
E29.8 Other testicular dysfunction
0.000 0.822 0.178
E29.0 Testicular hyperfunction
0.000 0.822 0.178
E25.9 Adrenogenital disorder, unspecified
0.000 0.822 0.178
E25.8 Other adrenogenital disorders
0.000 0.822 0.178
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.822 0.178
E30.9 Disorder of puberty, unspecified
0.000 0.822 0.178
E30.8 Other disorders of puberty
0.000 0.822 0.178
E30.1 Precocious puberty
0.000 0.822 0.178
E30.0 Delayed puberty
0.000 0.822 0.178
E32.9 Disease of thymus, unspecified
0.000 0.822 0.178
E32.8 Other diseases of thymus
0.000 0.822 0.178
E32.1 Abscess of thymus
0.000 0.822 0.178
E32.0 Persistent hyperplasia of thymus
0.000 0.822 0.178
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.822 0.178
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.822 0.178
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.822 0.178
E28.3 Primary ovarian failure
0.000 0.823 0.177
E53.9 Vitamin B deficiency, unspecified
0.000 0.825 0.175
E56.9 Vitamin deficiency, unspecified
0.000 0.827 0.173
E56.8 Deficiency of other vitamins
0.000 0.827 0.173
E56.0 Deficiency of vitamin E
0.000 0.827 0.173
E67 Other hyperalimentation
0.000 0.833 0.166
E68 Sequelae of hyperalimentation
0.000 0.833 0.166
E50.9 Vitamin A deficiency, unspecified
0.000 0.834 0.166
E50.8 Other manifestations of vitamin A deficiency
0.000 0.834 0.166
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.834 0.166
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.834 0.166
E50.5 Vitamin A deficiency with night blindness
0.000 0.834 0.166
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.834 0.166
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.834 0.166
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.834 0.166
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.834 0.166
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.834 0.166
E63.9 Nutritional deficiency, unspecified
0.000 0.834 0.166
E63.8 Other specified nutritional deficiencies
0.000 0.834 0.166
E63.1 Imbalance of constituents of food intake
0.000 0.834 0.166
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.834 0.166
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.834 0.166
E64.8 Sequelae of other nutritional deficiencies
0.000 0.834 0.166
E64.3 Sequelae of rickets
0.000 0.834 0.166
E64.2 Sequelae of vitamin C deficiency
0.000 0.834 0.166
E64.1 Sequelae of vitamin A deficiency
0.000 0.834 0.166
E64.0 Sequelae of protein-energy malnutrition
0.000 0.834 0.166
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.835 0.165
E22.8 Other hyperfunction of pituitary gland
0.000 0.835 0.165
E27 Other disorders of adrenal gland
0.000 0.836 0.164
E04.0 Non-toxic diffuse goitre
0.001 0.836 0.163
E31.9 Polyglandular dysfunction, unspecified
0.000 0.838 0.162
E31.8 Other polyglandular dysfunction
0.000 0.838 0.162
E31.1 Polyglandular hyperfunction
0.000 0.838 0.162
E28.9 Ovarian dysfunction, unspecified
0.000 0.838 0.161
E28.8 Other ovarian dysfunction
0.000 0.838 0.161
E28.1 Androgen excess
0.000 0.838 0.161
E28.0 Oestrogen excess
0.000 0.838 0.161
E61 Deficiency of other nutrient elements
0.000 0.840 0.160
E83.3 Disorders of phosphorus metabolism
0.158 0.842 0.000
E22.1 Hyperprolactinaemia
0.000 0.846 0.154
E83.9 Disorder of mineral metabolism, unspecified
0.148 0.851 0.000
E83.8 Other disorders of mineral metabolism
0.148 0.851 0.000
E83.2 Disorders of zinc metabolism
0.148 0.851 0.000
E83.0 Disorders of copper metabolism
0.148 0.851 0.000
E53.1 Pyridoxine deficiency
0.000 0.853 0.147
E53.0 Riboflavin deficiency
0.000 0.853 0.147
E26.9 Hyperaldosteronism, unspecified
0.000 0.854 0.146
E26.8 Other hyperaldosteronism
0.000 0.854 0.146
E26.1 Secondary hyperaldosteronism
0.000 0.854 0.146
E31.0 Autoimmune polyglandular failure
0.000 0.860 0.140
E55.0 Rickets, active
0.000 0.860 0.140
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.860 0.140
E34.5 Androgen resistance syndrome
0.000 0.864 0.136
E34.4 Constitutional tall stature
0.000 0.864 0.136
E34.3 Short stature, not elsewhere classified
0.000 0.864 0.136
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.864 0.136
E34.1 Other hypersecretion of intestinal hormones
0.000 0.864 0.136
E27.1 Primary adrenocortical insufficiency
0.000 0.867 0.133
E34.8 Other specified endocrine disorders
0.000 0.868 0.132
E65 Localised adiposity
0.000 0.870 0.130
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.872 0.128
E34.9 Endocrine disorder, unspecified
0.000 0.874 0.126
E11.3 With ophthalmic complications
0.000 0.880 0.120
E67.8 Other specified hyperalimentation
0.000 0.880 0.119
E67.3 Hypervitaminosis D
0.000 0.880 0.119
E67.2 Megavitamin-B6 syndrome
0.000 0.880 0.119
E67.1 Hypercarotenaemia
0.000 0.880 0.119
E67.0 Hypervitaminosis A
0.000 0.880 0.119
E27.5 Adrenomedullary hyperfunction
0.000 0.882 0.118
E27.0 Other adrenocortical overactivity
0.000 0.882 0.118
E06.3 Autoimmune thyroiditis
0.000 0.883 0.117
E83.4 Disorders of magnesium metabolism
0.117 0.883 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.883 0.117
E61.9 Deficiency of nutrient element, unspecified
0.000 0.885 0.115
E61.8 Deficiency of other specified nutrient elements
0.000 0.885 0.115
E61.7 Deficiency of multiple nutrient elements
0.000 0.885 0.115
E61.6 Vanadium deficiency
0.000 0.885 0.115
E61.5 Molybdenum deficiency
0.000 0.885 0.115
E61.4 Chromium deficiency
0.000 0.885 0.115
E61.3 Manganese deficiency
0.000 0.885 0.115
E61.0 Copper deficiency
0.000 0.885 0.115
E28.2 Polycystic ovarian syndrome
0.000 0.889 0.111
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.890 0.110
E27.9 Disorder of adrenal gland, unspecified
0.000 0.894 0.106
E55.9 Vitamin D deficiency, unspecified
0.000 0.896 0.103
E26.0 Primary hyperaldosteronism
0.000 0.898 0.101
E34.0 Carcinoid syndrome
0.000 0.898 0.101
E61.2 Magnesium deficiency
0.000 0.901 0.099
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.905 0.095
E21.3 Hyperparathyroidism, unspecified
0.000 0.907 0.093
E21.4 Other specified disorders of parathyroid gland
0.000 0.908 0.092
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.910 0.090
E21.2 Other hyperparathyroidism
0.000 0.912 0.088
E27.2 Addisonian crisis
0.000 0.915 0.084
E83.5 Disorders of calcium metabolism
0.080 0.920 0.000
K50-K52 Noninfective enteritis and colitis
0.078 0.922 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.922 0.077
E61.1 Iron deficiency
0.000 0.926 0.074
K50 Crohn's disease [regional enteritis]
0.051 0.949 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.953 0.046
K50.9 Crohn's disease, unspecified
0.042 0.958 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.961 0.039
K50.0 Crohn's disease of small intestine
0.039 0.961 0.000
K90-K93 Other diseases of the digestive system
0.001 0.969 0.030
K50.1 Crohn's disease of large intestine
0.030 0.970 0.000
E04.2 Non-toxic multinodular goitre
0.001 0.972 0.028
K50.8 Other Crohn's disease
0.026 0.974 0.000
E66 Obesity
0.000 0.975 0.025
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.025 0.975 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.977 0.023
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.978 0.022
E11.9 Without complications
0.000 0.978 0.022
H54.0 Blindness, both eyes
0.000 0.979 0.021
E21.0 Primary hyperparathyroidism
0.000 0.979 0.021
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.018 0.982 0.000
J38.3 Other diseases of vocal cords
0.018 0.982 0.000
E66.1 Drug-induced obesity
0.000 0.982 0.018
J38.7 Other diseases of larynx
0.018 0.982 0.000
J38.4 Oedema of larynx
0.018 0.982 0.000
J38.2 Nodules of vocal cords
0.018 0.982 0.000
C43.5 Malignant melanoma of trunk
0.000 0.983 0.017
H54 Blindness and low vision
0.000 0.984 0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.984 0.016
K93.1 Megacolon in Chagas' disease
0.001 0.984 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.984 0.016
J38.5 Laryngeal spasm
0.015 0.985 0.000
H54.9 Unspecified visual impairment (binocular)
0.000 0.985 0.015
E66.0 Obesity due to excess calories
0.000 0.986 0.014
H54.6 Unqualified visual loss, one eye
0.000 0.986 0.014
H54.7 Unspecified visual loss
0.000 0.987 0.013
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.987 0.013
H54.5 Low vision, one eye
0.000 0.987 0.013
H54.3 Unqualified visual loss, both eyes
0.000 0.988 0.012
I83 Varicose veins of lower extremities
0.012 0.988 0.000
V18.0 Driver injured in nontraffic accident
0.011 0.989 0.000
J38.1 Polyp of vocal cord and larynx
0.011 0.989 0.000
H54.4 Blindness, one eye
0.000 0.989 0.011
H54.1 Blindness, one eye, low vision, other eye
0.000 0.989 0.011
K04.5 Chronic apical periodontitis
0.011 0.989 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.989 0.011
J38.6 Stenosis of larynx
0.010 0.990 0.000
H54.2 Low vision, both eyes
0.000 0.990 0.010
S64.0 Injury of ulnar nerve at wrist and hand level
0.010 0.990 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.010 0.990 0.000
E66.8 Other obesity
0.000 0.991 0.009
I83.1 Varicose veins of lower extremities with inflammation
0.009 0.991 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.991 0.009
J38.0 Paralysis of vocal cords and larynx
0.008 0.991 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.992 0.008
Z99.1 Dependence on respirator
0.000 0.992 0.008
C43 Malignant melanoma of skin
0.000 0.992 0.008
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.993 0.007
A08 Viral and other specified intestinal infections
0.000 0.993 0.007
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.993 0.007
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.993 0.007
I83.0 Varicose veins of lower extremities with ulcer
0.007 0.993 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.994 0.006
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.994 0.006
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.994 0.006
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.994 0.006
K52 Other non-infective gastro-enteritis and colitis
0.006 0.994 0.000
C43.4 Malignant melanoma of scalp and neck
0.000 0.994 0.006
C43.8 Overlapping malignant melanoma of skin
0.000 0.994 0.006
C43.0 Malignant melanoma of lip
0.000 0.994 0.006
A08.3 Other viral enteritis
0.000 0.994 0.006
N18.5 Chronic kidney disease, stage 5
0.000 0.994 0.006
C43.9 Malignant melanoma of skin, unspecified
0.000 0.994 0.006
J81 Pulmonary oedema
0.000 0.994 0.006
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.994 0.006
V18 Pedal cyclist injured in noncollision transport accident
0.006 0.994 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.994 0.005
A08.5 Other specified intestinal infections
0.000 0.994 0.005
A08.2 Adenoviral enteritis
0.000 0.994 0.005
A08.0 Rotaviral enteritis
0.000 0.994 0.005
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.995 0.005
M25.76 Osteophyte (Lower leg)
0.000 0.995 0.005
S64 Injury of nerves at wrist and hand level
0.005 0.995 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.995 0.005
E70-E90 Metabolic disorders
0.001 0.995 0.004
H53-H54 Visual disturbances and blindness
0.000 0.995 0.005
Z99.8 Dependence on other enabling machines and devices
0.000 0.995 0.005
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.995 0.005
F45.8 Other somatoform disorders
0.000 0.995 0.005
S64.2 Injury of radial nerve at wrist and hand level
0.005 0.995 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.995 0.005
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.995 0.005
K52.0 Gastro-enteritis and colitis due to radiation
0.005 0.995 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.005 0.995 0.000
S64.1 Injury of median nerve at wrist and hand level
0.005 0.995 0.000
N60.2 Fibroadenosis of breast
0.005 0.995 0.000
H53.2 Diplopia
0.000 0.996 0.004
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.996 0.004
E73 Lactose intolerance
0.001 0.996 0.004
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.996 0.004
V18.5 Passenger injured in traffic accident
0.004 0.996 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.004 0.996 0.000
V18.4 Driver injured in traffic accident
0.004 0.996 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.996 0.004
E79 Disorders of purine and pyrimidine metabolism
0.001 0.996 0.003
X41.9 Unspecified place
0.004 0.996 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.004 0.996 0.000
V18.1 Passenger injured in nontraffic accident
0.004 0.996 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.004 0.996 0.000
S64.8 Injury of other nerves at wrist and hand level
0.004 0.996 0.000
N18.0 End-stage renal disease
0.000 0.996 0.004
S64.4 Injury of digital nerve of other finger
0.004 0.996 0.000
S42.10 Fracture of scapula (closed)
0.000 0.996 0.004
N87.9 Dysplasia of cervix uteri, unspecified
0.004 0.996 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.996 0.003
K92.1 Melaena
0.004 0.996 0.000
E77 Disorders of glycoprotein metabolism
0.001 0.996 0.003
E76 Disorders of glycosaminoglycan metabolism
0.001 0.996 0.003
E72 Other disorders of amino-acid metabolism
0.001 0.996 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.996 0.003
E70 Disorders of aromatic amino-acid metabolism
0.001 0.996 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.996 0.003
V18.3 Person injured while boarding or alighting
0.004 0.996 0.000
E74 Other disorders of carbohydrate metabolism
0.001 0.996 0.003
N18 Chronic renal failure
0.000 0.996 0.004
Z99.2 Dependence on renal dialysis
0.000 0.996 0.004
E73.9 Lactose intolerance, unspecified
0.000 0.996 0.004
E84 Cystic fibrosis
0.001 0.996 0.003
J35.8 Other chronic diseases of tonsils and adenoids
0.004 0.996 0.000
N85.1 Endometrial adenomatous hyperplasia
0.000 0.996 0.004
S64.7 Injury of multiple nerves at wrist and hand level
0.004 0.996 0.000
L53.9 Erythematous condition, unspecified
0.004 0.996 0.000
D30.3 Bladder
0.004 0.996 0.000
K92 Other diseases of digestive system
0.003 0.996 0.001
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.004 0.996 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.996 0.004
Z99.4 Dependence on artificial heart
0.000 0.996 0.004
Z99.0 Dependence on aspirator
0.000 0.996 0.004
K14.8 Other diseases of tongue
0.000 0.996 0.004
K52.1 Toxic gastro-enteritis and colitis
0.004 0.996 0.000
K92.0 Haematemesis
0.004 0.996 0.000
L43.9 Lichen planus, unspecified
0.000 0.996 0.004
R01.1 Cardiac murmur, unspecified
0.000 0.996 0.004
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.996 0.003
M62.82 Other specified disorders of muscle (Upper arm)
0.000 0.996 0.003
C15.5 Lower third of oesophagus
0.000 0.996 0.004
M25.71 Osteophyte (Shoulder region)
0.000 0.997 0.003
K52.3 Indeterminate colitis
0.003 0.997 0.000
E73.8 Other lactose intolerance
0.001 0.997 0.003
E73.1 Secondary lactase deficiency
0.001 0.997 0.003
E73.0 Congenital lactase deficiency
0.001 0.997 0.003
Q23.1 Congenital insufficiency of aortic valve
0.003 0.997 0.000
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
Q23 Congenital malformations of aortic and mitral valves
0.003 0.997 0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.003 0.997 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.003 0.997 0.000
M62.8 Other specified disorders of muscle
0.000 0.997 0.003
C50.3 Lower-inner quadrant of breast
0.000 0.997 0.003
Q23.0 Congenital stenosis of aortic valve
0.003 0.997 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.997 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.997 0.003
E79.1 Lesch-Nyhan syndrome
0.001 0.997 0.003
O43.8 Other placental disorders
0.000 0.997 0.003
E85 Amyloidosis
0.001 0.997 0.002
E75.5 Other lipid storage disorders
0.001 0.997 0.003
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.000 0.997 0.003
D47.4 Osteomyelofibrosis
0.000 0.997 0.003
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.997 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.997 0.002
E70.3 Albinism
0.001 0.997 0.002
E70.2 Disorders of tyrosine metabolism
0.001 0.997 0.002
E70.1 Other hyperphenylalaninaemias
0.001 0.997 0.002
E70.0 Classical phenylketonuria
0.001 0.997 0.002
E71.3 Disorders of fatty-acid metabolism
0.001 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.997 0.002
E71.0 Maple-syrup-urine disease
0.001 0.997 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.997 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.997 0.002
E72.5 Disorders of glycine metabolism
0.001 0.997 0.002
E72.4 Disorders of ornithine metabolism
0.001 0.997 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.997 0.002
E72.2 Disorders of urea cycle metabolism
0.001 0.997 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.997 0.002
E72.0 Disorders of amino-acid transport
0.001 0.997 0.002
E75.6 Lipid storage disorder, unspecified
0.001 0.997 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.997 0.002
E75.3 Sphingolipidosis, unspecified
0.001 0.997 0.002
E75.1 Other gangliosidosis
0.001 0.997 0.002
E75.0 GM2 gangliosidosis
0.001 0.997 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.997 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.997 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.997 0.002
E76.2 Other mucopolysaccharidoses
0.001 0.997 0.002
E76.1 Mucopolysaccharidosis, type II
0.001 0.997 0.002
E76.0 Mucopolysaccharidosis, type I
0.001 0.997 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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