TreeWAS – Variant ID: rs7770731

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.848	0.152
I08 Multiple valve diseases	0.000	0.850	0.150
I08.0 Disorders of both mitral and aortic valves	0.000	0.854	0.146
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.865	0.135
I08.9 Multiple valve disease, unspecified	0.000	0.891	0.109
I05-I09 Chronic rheumatic heart diseases	0.000	0.894	0.106
I08.8 Other multiple valve diseases	0.000	0.896	0.103
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.899	0.101
I05 Rheumatic mitral valve diseases	0.000	0.910	0.090
I09 Other rheumatic heart diseases	0.000	0.910	0.090
I07 Rheumatic tricuspid valve diseases	0.000	0.920	0.080
I09.9 Rheumatic heart disease, unspecified	0.000	0.922	0.078
I05.2 Mitral stenosis with insufficiency	0.000	0.926	0.074
G47.9 Sleep disorder, unspecified	0.000	0.928	0.072
I06 Rheumatic aortic valve diseases	0.000	0.928	0.072
I05.9 Mitral valve disease, unspecified	0.000	0.931	0.069
I05.1 Rheumatic mitral insufficiency	0.000	0.931	0.069
I05.0 Mitral stenosis	0.000	0.934	0.066
I05.8 Other mitral valve diseases	0.000	0.935	0.065
I09.8 Other specified rheumatic heart diseases	0.000	0.935	0.065
I09.2 Chronic rheumatic pericarditis	0.000	0.935	0.065
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.935	0.065
I09.0 Rheumatic myocarditis	0.000	0.935	0.065
D25.1 Intramural leiomyoma of uterus	0.061	0.939	0.000
I07.1 Tricuspid insufficiency	0.000	0.939	0.061
I07.9 Tricuspid valve disease, unspecified	0.000	0.943	0.057
I07.8 Other tricuspid valve diseases	0.000	0.943	0.057
I07.2 Tricuspid stenosis with insufficiency	0.000	0.943	0.057
I07.0 Tricuspid stenosis	0.000	0.943	0.057
I06.0 Rheumatic aortic stenosis	0.000	0.947	0.053
I06.8 Other rheumatic aortic valve diseases	0.000	0.948	0.051
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.948	0.051
I06.1 Rheumatic aortic insufficiency	0.000	0.948	0.051
G47 Sleep disorders	0.000	0.954	0.046
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.955	0.045
D25.2 Subserosal leiomyoma of uterus	0.044	0.956	0.000
D25 Leiomyoma of uterus	0.042	0.958	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.959	0.041
G47.8 Other sleep disorders	0.000	0.961	0.039
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.962	0.038
G47.4 Narcolepsy and cataplexy	0.000	0.963	0.037
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.966	0.034
G47.2 Disorders of the sleep-wake schedule	0.000	0.967	0.033
D25.0 Submucous leiomyoma of uterus	0.025	0.975	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.976	0.024
Z99.1 Dependence on respirator	0.000	0.979	0.021
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.982	0.018
Z99.2 Dependence on renal dialysis	0.000	0.982	0.018
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.983	0.017
A49 Bacterial infection of unspecified site	0.000	0.983	0.017
A49.9 Bacterial infection, unspecified	0.000	0.984	0.016
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.984	0.016
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.985	0.015
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.986	0.014
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.986	0.014
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.987	0.013
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.987	0.013
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.987	0.013
Z99.3 Dependence on wheelchair	0.000	0.987	0.013
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.987	0.013
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.987	0.012
Z99.4 Dependence on artificial heart	0.000	0.987	0.012
Z99.0 Dependence on aspirator	0.000	0.987	0.012
A49.3 Mycoplasma infection, unspecified	0.000	0.988	0.012
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.988	0.012
A49.1 Streptococcal infection, unspecified	0.000	0.988	0.012
A49.8 Other bacterial infections of unspecified site	0.000	0.988	0.012
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.988	0.012
Z99.8 Dependence on other enabling machines and devices	0.000	0.988	0.012
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.988	0.012
Z36.8 Other antenatal screening	0.012	0.988	0.000
G47.3 Sleep apnoea	0.000	0.989	0.011
T82.1 Mechanical complication of cardiac electronic device	0.000	0.989	0.011
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.989	0.011
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.990	0.010
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.991	0.009
I50.1 Left ventricular failure	0.000	0.991	0.009
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.991	0.009
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.008	0.992	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.992	0.008
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.992	0.008
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.992	0.008
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.992	0.008
T82.3 Mechanical complication of other vascular grafts	0.000	0.992	0.008
I67.8 Other specified cerebrovascular diseases	0.000	0.992	0.008
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.993	0.007
N87.1 Moderate cervical dysplasia	0.007	0.993	0.000
I50 Heart failure	0.000	0.993	0.007
I67 Other cerebrovascular diseases	0.000	0.993	0.007
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.993	0.007
T88.5 Other complications of anaesthesia	0.000	0.993	0.007
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.993	0.007
T87.4 Infection of amputation stump	0.000	0.993	0.006
T87 Complications peculiar to reattachment and amputation	0.000	0.994	0.006
M06.9 Rheumatoid arthritis, unspecified	0.006	0.994	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.994	0.006
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.006	0.994	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.006	0.994	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.994	0.006
T88.4 Failed or difficult intubation	0.000	0.994	0.006
T87.6 Other and unspecified complications of amputation stump	0.000	0.994	0.006
I50.0 Congestive heart failure	0.000	0.994	0.006
T87.3 Neuroma of amputation stump	0.000	0.994	0.006
J36 Peritonsillar abscess	0.006	0.994	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.006	0.994	0.000
I50.9 Heart failure, unspecified	0.000	0.994	0.006
G31.8 Other specified degenerative diseases of nervous system	0.005	0.995	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.995	0.005
I67.2 Cerebral atherosclerosis	0.000	0.995	0.005
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.995	0.005
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.995	0.005
I67.5 Moyamoya disease	0.000	0.995	0.005
I67.4 Hypertensive encephalopathy	0.000	0.995	0.005
I67.3 Progressive vascular leukoencephalopathy	0.000	0.995	0.005
I69 Sequelae of cerebrovascular disease	0.000	0.995	0.005
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.000	0.995	0.005
T87.5 Necrosis of amputation stump	0.000	0.995	0.005
T87.2 Complications of other reattached body part	0.000	0.995	0.005
T87.1 Complications of reattached (part of) lower extremity	0.000	0.995	0.005
T87.0 Complications of reattached (part of) upper extremity	0.000	0.995	0.005
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.995	0.005
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.995	0.005
T88.2 Shock due to anaesthesia	0.000	0.995	0.005
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.995	0.005
T88.0 Infection following immunisation	0.000	0.995	0.005
I45.8 Other specified conduction disorders	0.000	0.995	0.005
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.005	0.995	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.996	0.004
T88.9 Complication of surgical and medical care, unspecified	0.000	0.996	0.004
I45.9 Conduction disorder, unspecified	0.000	0.996	0.004
I45 Other conduction disorders	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.000	0.996	0.004
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.996	0.004
M06.98 Rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
I60-I69 Cerebrovascular diseases	0.000	0.996	0.004
Chapter IX Diseases of the circulatory system	0.000	0.996	0.004
I42 Cardiomyopathy	0.000	0.996	0.004
D25.9 Leiomyoma of uterus, unspecified	0.004	0.996	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.996	0.004
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.996	0.004
I63 Cerebral infarction	0.000	0.996	0.004
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.996	0.004
I42.2 Other hypertrophic cardiomyopathy	0.000	0.996	0.004
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
I45.4 Nonspecific intraventricular block	0.000	0.996	0.004
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.996	0.004
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.001	0.996	0.003
M06 Other rheumatoid arthritis	0.004	0.996	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.996	0.004
K81.9 Cholecystitis, unspecified	0.000	0.996	0.004
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.996	0.004
I46.0 Cardiac arrest with successful resuscitation	0.000	0.996	0.004
J92.9 Pleural plaque without asbestos	0.004	0.996	0.000
I45.5 Other specified heart block	0.000	0.996	0.004
J92.0 Pleural plaque with presence of asbestos	0.004	0.996	0.000
I30-I52 Other forms of heart disease	0.000	0.996	0.004
M06.3 Rheumatoid nodule	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.000	0.997	0.003
I45.0 Right fascicular block	0.000	0.997	0.003
T86 Failure and rejection of transplanted organs and tissues	0.000	0.997	0.003
M06.32 Rheumatoid nodule (Upper arm)	0.003	0.997	0.000
I45.3 Trifascicular block	0.000	0.997	0.003
I70 Atherosclerosis	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.000	0.997	0.003
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.000	0.997	0.003
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.997	0.003
I34 Nonrheumatic mitral valve disorders	0.000	0.997	0.003
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.003
I45.6 Preexcitation syndrome	0.000	0.997	0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.997	0.003
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.997	0.003
I42.5 Other restrictive cardiomyopathy	0.000	0.997	0.003
I42.4 Endocardial fibroelastosis	0.000	0.997	0.003
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.997	0.003
M06.8 Other specified rheumatoid arthritis	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
I46 Cardiac arrest	0.000	0.997	0.003
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
I00-I02 Acute rheumatic fever	0.000	0.997	0.003
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.997	0.003
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.997	0.003
I45.2 Bifascicular block	0.000	0.997	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.997	0.003
V23.4 Driver injured in traffic accident	0.003	0.997	0.000
M06.4 Inflammatory polyarthropathy	0.003	0.997	0.000
H33.0 Retinal detachment with retinal break	0.000	0.997	0.003
I70.0 Atherosclerosis of aorta	0.000	0.997	0.003
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.003
J92 Pleural plaque	0.003	0.997	0.000
M06.2 Rheumatoid bursitis	0.003	0.997	0.000
M06.1 Adult-onset Still's disease	0.003	0.997	0.000
S62.5 Fracture of thumb	0.000	0.997	0.003
L27 Dermatitis due to substances taken internally	0.000	0.997	0.003
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.997	0.003
S62.51 Fracture of thumb (open)	0.000	0.997	0.003
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.997	0.003
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
T80.6 Other serum reactions	0.000	0.997	0.003
T80.5 Anaphylactic shock due to serum	0.000	0.997	0.003
T80.4 Rh incompatibility reaction	0.000	0.997	0.003
T80.3 ABO incompatibility reaction	0.000	0.997	0.003
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
Z45.8 Adjustment and management of other implanted devices	0.000	0.997	0.003
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.997	0.003
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
O70.1 Second degree perineal laceration during delivery	0.003	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.997	0.003
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
T86.4 Liver transplant failure and rejection	0.000	0.997	0.003
I36 Nonrheumatic tricuspid valve disorders	0.000	0.997	0.003
I28 Other diseases of pulmonary vessels	0.000	0.997	0.003
I52 Other heart disorders in diseases classified elsewhere	0.000	0.997	0.003
I48 Atrial fibrillation and flutter	0.000	0.997	0.003
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.997	0.003
I41 Myocarditis in diseases classified elsewhere	0.000	0.997	0.003
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.997	0.003
I32 Pericarditis in diseases classified elsewhere	0.000	0.997	0.003
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.997	0.003
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.997	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.997	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.997	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.997	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.997	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.997	0.000
S60 Superficial injury of wrist and hand	0.000	0.997	0.003
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.997	0.003
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.997	0.003
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.997	0.003
T86.3 Heart-lung transplant failure and rejection	0.000	0.997	0.003
T86.2 Heart transplant failure and rejection	0.000	0.997	0.003
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.997	0.003
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.003
T86.0 Bone-marrow transplant rejection	0.000	0.997	0.003
I28.8 Other specified diseases of pulmonary vessels	0.000	0.997	0.003
T86.1 Kidney transplant failure and rejection	0.000	0.997	0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.997	0.003
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.997	0.003
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.003
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.997	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.997	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.997	0.002
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.997	0.003
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.997	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.997	0.002
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.997	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.997	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.997	0.002
M06.88 Other specified rheumatoid arthritis (Other)	0.002	0.997	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.002	0.997	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.997	0.000
I49.3 Ventricular premature depolarisation	0.000	0.997	0.003
Z36 Antenatal screening	0.003	0.997	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.997	0.000
I71.0 Dissection of aorta [any part]	0.000	0.997	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.997	0.002
Z98.0 Intestinal bypass and anastomosis status	0.000	0.997	0.003
I02 Rheumatic chorea	0.000	0.997	0.002
I01 Rheumatic fever with heart involvement	0.000	0.997	0.002
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.997	0.000
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
G40-G47 Episodic and paroxysmal disorders	0.000	0.997	0.003
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.997	0.002
I63.8 Other cerebral infarction	0.000	0.997	0.002
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.997	0.000
I35.8 Other aortic valve disorders	0.000	0.997	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.997	0.002
S60.8 Other superficial injuries of wrist and hand	0.000	0.997	0.002
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.002
I37 Pulmonary valve disorders	0.000	0.998	0.002
L84 Corns and callosities	0.002	0.998	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.998	0.002
I30 Acute pericarditis	0.000	0.998	0.002
I00 Rheumatic fever without mention of heart involvement	0.000	0.998	0.002
I27 Other pulmonary heart diseases	0.000	0.998	0.002
N04.9 Unspecified	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.998	0.002
M06.48 Inflammatory polyarthropathy (Other)	0.002	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.002	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.002	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.002	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.000	0.998	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.998	0.002
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
S60-S69 Injuries to the wrist and hand	0.000	0.998	0.002
I40 Acute myocarditis	0.000	0.998	0.002
I72 Other aneurysm	0.000	0.998	0.002
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.998	0.000
M06.18 Adult-onset Still's disease (Other)	0.002	0.998	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.002	0.998	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.002	0.998	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.002	0.998	0.000
M06.14 Adult-onset Still's disease (Hand)	0.002	0.998	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.002	0.998	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.002	0.998	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.002	0.998	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.002	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.002	0.998	0.000
M06.28 Rheumatoid bursitis (Other)	0.002	0.998	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.002	0.998	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.002	0.998	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.002	0.998	0.000
M06.24 Rheumatoid bursitis (Hand)	0.002	0.998	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.002	0.998	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.002	0.998	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.002	0.998	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.998	0.002
L27.8 Dermatitis due to other substances taken internally	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
S60.0 Contusion of finger(s) without damage to nail	0.000	0.998	0.002
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
I35 Nonrheumatic aortic valve disorders	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.998	0.002
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.998	0.002
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.998	0.002
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
G40 Epilepsy	0.000	0.998	0.002
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.998	0.002
I28.1 Aneurysm of pulmonary artery	0.000	0.998	0.002
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.998	0.002
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.998	0.002
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.998	0.002
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.998	0.002
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.998	0.002
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.998	0.002
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.998	0.002
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.998	0.002
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.998	0.002
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.998	0.002
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.998	0.002
I48.4 Atypical atrial flutter	0.000	0.998	0.002
I48.3 Typical atrial flutter	0.000	0.998	0.002
I48.2 Chronic atrial fibrillation	0.000	0.998	0.002
I48.1 Persistent atrial fibrillation	0.000	0.998	0.002
I48.0 Paroxysmal atrial fibrillation	0.000	0.998	0.002
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.998	0.002
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
I49 Other cardiac arrhythmias	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.998	0.002
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.998	0.002
I46.1 Sudden cardiac death, so described	0.000	0.998	0.002
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.000	0.998	0.002
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C44.1 Skin of eyelid, including canthus	0.002	0.998	0.000
L27.2 Dermatitis due to ingested food	0.000	0.998	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.998	0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.998	0.002
I79.1 Aortitis in diseases classified elsewhere	0.000	0.998	0.002
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.998	0.002
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.002
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.998	0.002
I72.0 Aneurysm of carotid artery	0.000	0.998	0.002
Z03.3 Observation for suspected nervous system disorder	0.000	0.998	0.002
Z36.0 Antenatal screening for chromosomal anomalies	0.002	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.002
I30.1 Infective pericarditis	0.000	0.998	0.002
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
I33 Acute and subacute endocarditis	0.000	0.998	0.002
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
G43.1 Migraine with aura [classical migraine]	0.000	0.998	0.002
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.998	0.002
I01.8 Other acute rheumatic heart disease	0.000	0.998	0.002
I01.2 Acute rheumatic myocarditis	0.000	0.998	0.002
I01.1 Acute rheumatic endocarditis	0.000	0.998	0.002
I01.0 Acute rheumatic pericarditis	0.000	0.998	0.002
I02.9 Rheumatic chorea without heart involvement	0.000	0.998	0.002
I02.0 Rheumatic chorea with heart involvement	0.000	0.998	0.002
I31 Other diseases of pericardium	0.000	0.998	0.002
N87.2 Severe cervical dysplasia, not elsewhere classified	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.000	0.998	0.002
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.998	0.002
I37.9 Pulmonary valve disorder, unspecified	0.000	0.998	0.002
I37.8 Other pulmonary valve disorders	0.000	0.998	0.002
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.998	0.002
I37.0 Pulmonary valve stenosis	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.001	0.998	0.001
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
I40.8 Other acute myocarditis	0.000	0.998	0.002
I40.1 Isolated myocarditis	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.998	0.002
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.000	0.998	0.002
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.000	0.998	0.002
S60.1 Contusion of finger(s) with damage to nail	0.000	0.998	0.002
I97.1 Other functional disturbances following cardiac surgery	0.000	0.998	0.002
S60.2 Contusion of other parts of wrist and hand	0.000	0.998	0.002
A46 Erysipelas	0.000	0.998	0.002
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.998	0.002
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
I49.2 Junctional premature depolarisation	0.000	0.998	0.002
N87 Dysplasia of cervix uteri	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
G40.9 Epilepsy, unspecified	0.000	0.998	0.002
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.000	0.998	0.002
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.998	0.002
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
I40.0 Infective myocarditis	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
S61.0 Open wound of finger(s) without damage to nail	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
E07 Other disorders of thyroid	0.000	0.998	0.002
G40.5 Special epileptic syndromes	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.000	0.998	0.002
I33.9 Acute endocarditis, unspecified	0.000	0.998	0.001
I72.2 Aneurysm of renal artery	0.000	0.998	0.002
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.998	0.002
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.002
G46.4 Cerebellar stroke syndrome	0.000	0.998	0.002
I31.9 Disease of pericardium, unspecified	0.000	0.998	0.002
I31.8 Other specified diseases of pericardium	0.000	0.998	0.002
I31.2 Haemopericardium, not elsewhere classified	0.000	0.998	0.002
I31.1 Chronic constrictive pericarditis	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
R40.0 Somnolence	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations