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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77727170
log Bayes Factor = 12.9342
Chromosome 6   position 141,312,506  (GRCh37) Explore rs77727170 on Ensembl!
Variant rs77727170 is part of Cluster X0110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
J30-J39 Other diseases of upper respiratory tract
0.994 0.006 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.992 0.008 0.000
S00-S09 Injuries to the head
0.989 0.011 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.984 0.016 0.000
R50-R69 General symptoms and signs
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.982 0.018 0.000
R63 Symptoms and signs concerning food and fluid intake
0.981 0.019 0.000
R63.4 Abnormal weight loss
0.979 0.021 0.000
I60-I69 Cerebrovascular diseases
0.976 0.024 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.971 0.029 0.000
J95-J99 Other diseases of the respiratory system
0.963 0.037 0.000
J38.3 Other diseases of vocal cords
0.961 0.039 0.000
I69 Sequelae of cerebrovascular disease
0.960 0.040 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.956 0.044 0.000
J38.1 Polyp of vocal cord and larynx
0.954 0.046 0.000
Chapter VII Diseases of the eye and adnexa
0.948 0.052 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.946 0.054 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.946 0.054 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.945 0.055 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.944 0.056 0.000
T81 Complications of procedures, not elsewhere classified
0.943 0.057 0.000
J98 Other respiratory disorders
0.937 0.063 0.000
H02 Other disorders of eyelid
0.937 0.063 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.933 0.067 0.000
J90-J94 Other diseases of pleura
0.933 0.067 0.000
S20-S29 Injuries to the thorax
0.928 0.072 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.923 0.077 0.000
J09-J18 Influenza and pneumonia
0.922 0.078 0.000
G81 Hemiplegia
0.922 0.078 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.911 0.089 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.909 0.091 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.908 0.092 0.000
G90-G99 Other disorders of the nervous system
0.905 0.095 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.902 0.098 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.901 0.099 0.000
Chapter XXII Codes for special purposes
0.899 0.101 0.000
M50-M54 Other dorsopathies
0.898 0.102 0.000
S06 Intracranial injury
0.896 0.104 0.000
S01 Open wound of head
0.892 0.108 0.000
M54 Dorsalgia
0.890 0.110 0.000
G81.9 Hemiplegia, unspecified
0.886 0.114 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.885 0.115 0.000
J20-J22 Other acute lower respiratory infections
0.883 0.117 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.880 0.120 0.000
M54.5 Low back pain
0.878 0.122 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.876 0.124 0.000
G57 Mononeuropathies of lower limb
0.875 0.125 0.000
J00-J06 Acute upper respiratory infections
0.875 0.125 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.873 0.127 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.872 0.128 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.870 0.130 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.870 0.130 0.000
G58 Other mononeuropathies
0.870 0.130 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.869 0.131 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.864 0.136 0.000
J36 Peritonsillar abscess
0.863 0.137 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.863 0.137 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.860 0.140 0.000
R61 Hyperhidrosis
0.860 0.140 0.000
H02.0 Entropion and trichiasis of eyelid
0.859 0.141 0.000
G82 Paraplegia and tetraplegia
0.853 0.147 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.852 0.148 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.849 0.151 0.000
H02.8 Other specified disorders of eyelid
0.848 0.152 0.000
J98.1 Pulmonary collapse
0.846 0.154 0.000
R50 Fever of unknown origin
0.846 0.154 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.845 0.155 0.000
S00 Superficial injury of head
0.844 0.156 0.000
S40-S49 Injuries to the shoulder and upper arm
0.844 0.156 0.000
J86 Pyothorax
0.842 0.158 0.000
J90 Pleural effusion, not elsewhere classified
0.841 0.159 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.838 0.162 0.000
I67 Other cerebrovascular diseases
0.834 0.166 0.000
J38.7 Other diseases of larynx
0.831 0.169 0.000
H02.6 Xanthelasma of eyelid
0.830 0.170 0.000
H02.1 Ectropion of eyelid
0.829 0.171 0.000
G54 Nerve root and plexus disorders
0.828 0.172 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.826 0.174 0.000
I63 Cerebral infarction
0.823 0.177 0.000
H04 Disorders of lachrymal system
0.823 0.177 0.000
I69.3 Sequelae of cerebral infarction
0.821 0.179 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.821 0.179 0.000
G40-G47 Episodic and paroxysmal disorders
0.820 0.180 0.000
T66-T78 Other and unspecified effects of external causes
0.819 0.181 0.000
M54.59 Low back pain (Site unspecified)
0.819 0.181 0.000
S01.0 Open wound of scalp
0.819 0.181 0.000
J98.4 Other disorders of lung
0.818 0.182 0.000
D60-D64 Aplastic and other anaemias
0.817 0.183 0.000
R29.6 Tendency to fall, not elsewhere classified
0.816 0.184 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.815 0.185 0.000
R47-R49 Symptoms and signs involving speech and voice
0.814 0.186 0.000
S90-S99 Injuries to the ankle and foot
0.814 0.186 0.000
R56 Convulsions, not elsewhere classified
0.813 0.187 0.000
I95 Hypotension
0.813 0.187 0.000
R26 Abnormalities of gait and mobility
0.811 0.189 0.000
T79-T79 Certain early complications of trauma
0.811 0.189 0.000
S32 Fracture of lumbar spine and pelvis
0.802 0.198 0.000
H18 Other disorders of cornea
0.800 0.200 0.000
S02 Fracture of skull and facial bones
0.800 0.200 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.799 0.201 0.000
G20-G26 Extrapyramidal and movement disorders
0.798 0.202 0.000
S05 Injury of eye and orbit
0.798 0.202 0.000
R60 Oedema, not elsewhere classified
0.797 0.203 0.000
J22 Unspecified acute lower respiratory infection
0.796 0.204 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.794 0.206 0.000
S80-S89 Injuries to the knee and lower leg
0.793 0.207 0.000
H02.4 Ptosis of eyelid
0.792 0.208 0.000
M54.56 Low back pain (Lumbar region)
0.792 0.208 0.000
J38.2 Nodules of vocal cords
0.791 0.209 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.790 0.210 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.789 0.211 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.784 0.216 0.000
S01.8 Open wound of other parts of head
0.783 0.216 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.782 0.218 0.000
T86 Failure and rejection of transplanted organs and tissues
0.782 0.218 0.000
Chapter I Certain infectious and parasitic diseases
0.780 0.220 0.000
I95.9 Hypotension, unspecified
0.778 0.222 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.777 0.223 0.000
J93 Pneumothorax
0.774 0.226 0.000
R61.9 Hyperhidrosis, unspecified
0.771 0.229 0.000
G57.6 Lesion of plantar nerve
0.771 0.229 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.769 0.231 0.000
M54.57 Low back pain (Lumbosacral region)
0.768 0.232 0.000
J91 Pleural effusion in conditions classified elsewhere
0.766 0.234 0.000
S00.0 Superficial injury of scalp
0.765 0.235 0.000
S06.5 Traumatic subdural haemorrhage
0.764 0.236 0.000
J60-J70 Lung diseases due to external agents
0.762 0.238 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.761 0.239 0.000
J98.8 Other specified respiratory disorders
0.761 0.239 0.000
J86.9 Pyothorax without fistula
0.760 0.240 0.000
J18 Pneumonia, organism unspecified
0.759 0.241 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.757 0.243 0.000
T93 Sequelae of injuries of lower limb
0.756 0.244 0.000
I67.9 Cerebrovascular disease, unspecified
0.753 0.247 0.000
R50.9 Fever, unspecified
0.751 0.249 0.000
T88.4 Failed or difficult intubation
0.750 0.250 0.000
J38.0 Paralysis of vocal cords and larynx
0.749 0.251 0.000
M50 Cervical disk disorders
0.745 0.255 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.745 0.255 0.000
J38.4 Oedema of larynx
0.744 0.256 0.000
G58.8 Other specified mononeuropathies
0.743 0.257 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.743 0.257 0.000
M54.2 Cervicalgia
0.741 0.259 0.000
H18.5 Hereditary corneal dystrophies
0.741 0.259 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.739 0.260 0.000
G35 Multiple sclerosis
0.739 0.261 0.000
S70-S79 Injuries to the hip and thigh
0.739 0.261 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.739 0.261 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.737 0.263 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.737 0.263 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.736 0.264 0.000
S06.0 Concussion
0.735 0.265 0.000
J33 Nasal polyp
0.735 0.265 0.000
S22.0 Fracture of thoracic vertebra
0.733 0.267 0.000
D80-D89 Certain disorders involving the immune mechanism
0.732 0.268 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.731 0.269 0.000
G91 Hydrocephalus
0.731 0.269 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.730 0.270 0.000
S29 Other and unspecified injuries of thorax
0.729 0.271 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.728 0.272 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.728 0.272 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.727 0.273 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.727 0.273 0.000
T81.9 Unspecified complication of procedure
0.723 0.277 0.000
G44 Other headache syndromes
0.722 0.278 0.000
G30-G32 Other degenerative diseases of the nervous system
0.721 0.279 0.000
S10-S19 Injuries to the neck
0.720 0.280 0.000
J11 Influenza, virus not identified
0.719 0.281 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.719 0.281 0.000
R52 Pain, not elsewhere classified
0.719 0.281 0.000
J00 Acute nasopharyngitis [common cold]
0.719 0.281 0.000
D75 Other diseases of blood and blood-forming organs
0.718 0.282 0.000
G90 Disorders of autonomic nervous system
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.717 0.283 0.000
H05 Disorders of orbit
0.717 0.283 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.715 0.285 0.000
R55 Syncope and collapse
0.713 0.287 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.713 0.287 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
M05-M14 Inflammatory polyarthropathies
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.287 0.000
J37 Chronic laryngitis and laryngotracheitis
0.712 0.288 0.000
J38.6 Stenosis of larynx
0.711 0.289 0.000
J38.5 Laryngeal spasm
0.711 0.289 0.000
I63.9 Cerebral infarction, unspecified
0.711 0.289 0.000
S09 Other and unspecified injuries of head
0.710 0.290 0.000
G58.9 Mononeuropathy, unspecified
0.710 0.290 0.000
S08 Traumatic amputation of part of head
0.709 0.291 0.000
S07 Crushing injury of head
0.709 0.291 0.000
S04 Injury of cranial nerves
0.709 0.291 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.709 0.291 0.000
S82 Fracture of lower leg, including ankle
0.708 0.292 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.707 0.292 0.000
R27 Other lack of coordination
0.707 0.293 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.706 0.294 0.000
G52 Disorders of other cranial nerves
0.706 0.294 0.000
J86.0 Pyothorax with fistula
0.706 0.294 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.705 0.295 0.000
R62 Lack of expected normal physiological development
0.705 0.295 0.000
R57 Shock, not elsewhere classified
0.705 0.295 0.000
R64 Cachexia
0.705 0.295 0.000
R58 Haemorrhage, not elsewhere classified
0.705 0.295 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
R59 Enlarged lymph nodes
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.704 0.296 0.000
R63.5 Abnormal weight gain
0.704 0.296 0.000
R63.3 Feeding difficulties and mismanagement
0.704 0.296 0.000
R63.2 Polyphagia
0.704 0.296 0.000
R63.1 Polydipsia
0.704 0.296 0.000
G83 Other paralytic syndromes
0.703 0.296 0.000
H01 Other inflammation of eyelid
0.702 0.297 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.702 0.298 0.000
S27 Injury of other and unspecified intrathoracic organs
0.702 0.298 0.000
T88.5 Other complications of anaesthesia
0.701 0.298 0.000
I61 Intracerebral haemorrhage
0.701 0.299 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.700 0.300 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.700 0.300 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.700 0.300 0.000
S42 Fracture of shoulder and upper arm
0.700 0.300 0.000
G50 Disorders of trigeminal nerve
0.699 0.300 0.000
G95 Other diseases of spinal cord
0.699 0.301 0.000
Q60-Q64 Congenital malformations of the urinary system
0.698 0.302 0.000
M54.4 Lumbago with sciatica
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.302 0.000
S20 Superficial injury of thorax
0.697 0.302 0.000
G82.2 Paraplegia, unspecified
0.697 0.303 0.000
Chapter VIII Diseases of the ear and mastoid process
0.696 0.304 0.000
G80 Infantile cerebral palsy
0.696 0.304 0.000
G37 Other demyelinating diseases of central nervous system
0.696 0.304 0.000
S60-S69 Injuries to the wrist and hand
0.695 0.305 0.000
G62 Other polyneuropathies
0.695 0.305 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.694 0.306 0.000
I05-I09 Chronic rheumatic heart diseases
0.694 0.306 0.000
R56.8 Other and unspecified convulsions
0.691 0.309 0.000
M40-M43 Deforming dorsopathies
0.691 0.309 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.691 0.309 0.000
J96 Respiratory failure, not elsewhere classified
0.691 0.309 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.691 0.309 0.000
G61 Inflammatory polyneuropathy
0.690 0.310 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
R26.0 Ataxic gait
0.689 0.311 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.688 0.312 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.688 0.312 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.688 0.312 0.000
M60-M63 Disorders of muscles
0.688 0.312 0.000
G57.8 Other mononeuropathies of lower limb
0.688 0.312 0.000
D73 Diseases of spleen
0.687 0.313 0.000
R49 Voice disturbances
0.687 0.313 0.000
G82.5 Tetraplegia, unspecified
0.686 0.314 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.686 0.314 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.686 0.314 0.000
H55-H59 Other disorders of eye and adnexa
0.685 0.315 0.000
I67.8 Other specified cerebrovascular diseases
0.685 0.315 0.000
S06.8 Other intracranial injuries
0.684 0.315 0.000
S01.1 Open wound of eyelid and periocular area
0.684 0.316 0.000
G93 Other disorders of brain
0.683 0.317 0.000
T31 Burns classified according to extent of body surface involved
0.683 0.317 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.682 0.318 0.000
U80 Agent resistant to penicillin and related antibiotics
0.682 0.318 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.681 0.319 0.000
S22.4 Multiple fractures of ribs
0.680 0.319 0.000
D70 Agranulocytosis
0.680 0.320 0.000
G51 Facial nerve disorders
0.680 0.320 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.680 0.320 0.000
M00-M03 Infectious arthropathies
0.679 0.321 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.679 0.321 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.678 0.321 0.000
D55-D59 Haemolytic anaemias
0.678 0.322 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.678 0.322 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.677 0.323 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.677 0.323 0.000
M54.1 Radiculopathy
0.676 0.324 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.676 0.324 0.000
I30-I52 Other forms of heart disease
0.676 0.324 0.000
G70-G73 Diseases of myoneural junction and muscle
0.676 0.324 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.675 0.325 0.000
H04.2 Epiphora
0.674 0.326 0.000
G54.0 Brachial plexus disorders
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.673 0.327 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.673 0.327 0.000
J98.9 Respiratory disorder, unspecified
0.672 0.328 0.000
J98.6 Disorders of diaphragm
0.672 0.328 0.000
J98.3 Compensatory emphysema
0.672 0.328 0.000
J98.2 Interstitial emphysema
0.672 0.328 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.672 0.328 0.000
H02.2 Lagophthalmos
0.672 0.328 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.672 0.328 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.330 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.670 0.330 0.000
J15.1 Pneumonia due to Pseudomonas
0.668 0.332 0.000
J94 Other pleural conditions
0.666 0.334 0.000
G82.1 Spastic paraplegia
0.666 0.334 0.000
M54.50 Low back pain (Multiple sites in spine)
0.665 0.334 0.000
H53-H54 Visual disturbances and blindness
0.665 0.334 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.665 0.335 0.000
S26 Injury of heart
0.665 0.335 0.000
S25 Injury of blood vessels of thorax
0.665 0.335 0.000
S24 Injury of nerves and spinal cord at thorax level
0.665 0.335 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.665 0.335 0.000
S21 Open wound of thorax
0.665 0.335 0.000
J93.9 Pneumothorax, unspecified
0.665 0.335 0.000
G20 Parkinson's disease
0.665 0.335 0.000
M80-M85 Disorders of bone density and structure
0.664 0.336 0.000
T91 Sequelae of injuries of neck and trunk
0.662 0.338 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.661 0.338 0.000
T85.2 Mechanical complication of intraocular lens
0.661 0.338 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.661 0.338 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.661 0.338 0.000
R25 Abnormal involuntary movements
0.661 0.339 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.661 0.339 0.000
J17 Pneumonia in diseases classified elsewhere
0.661 0.339 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.661 0.339 0.000
J12 Viral pneumonia, not elsewhere classified
0.661 0.339 0.000
J10 Influenza due to identified influenza virus
0.661 0.339 0.000
J14 Pneumonia due to Haemophilus influenzae
0.661 0.339 0.000
J09 Influenza due to certain identified influenza virus
0.661 0.339 0.000
G81.1 Spastic hemiplegia
0.661 0.339 0.000
G81.0 Flaccid hemiplegia
0.661 0.339 0.000
S05.8 Other injuries of eye and orbit
0.660 0.340 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.660 0.340 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.660 0.340 0.000
I60 Subarachnoid haemorrhage
0.659 0.341 0.000
H10-H13 Disorders of conjunctiva
0.659 0.341 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.659 0.341 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.658 0.342 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.658 0.342 0.000
J18.9 Pneumonia, unspecified
0.657 0.343 0.000
M86-M90 Other osteopathies
0.656 0.344 0.000
J02 Acute pharyngitis
0.656 0.344 0.000
D61 Other aplastic anaemias
0.655 0.344 0.000
J34 Other disorders of nose and nasal sinuses
0.655 0.345 0.000
M50.2 Other cervical disk displacement
0.655 0.345 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.654 0.346 0.000
R68 Other general symptoms and signs
0.653 0.347 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.653 0.347 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.651 0.348 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.651 0.348 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.651 0.349 0.000
T90 Sequelae of injuries of head
0.651 0.349 0.000
J85 Abscess of lung and mediastinum
0.651 0.349 0.000
I62 Other nontraumatic intracranial haemorrhage
0.651 0.349 0.000
S06.2 Diffuse brain injury
0.650 0.350 0.000
S82.6 Fracture of lateral malleolus
0.649 0.351 0.000
T78 Adverse effects, not elsewhere classified
0.649 0.351 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.649 0.351 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.649 0.351 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.649 0.351 0.000
G92 Toxic encephalopathy
0.649 0.351 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.649 0.351 0.000
R50.8 Other specified fever
0.649 0.351 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.649 0.351 0.000
S02.2 Fracture of nasal bones
0.648 0.352 0.000
T86.1 Kidney transplant failure and rejection
0.648 0.352 0.000
J04 Acute laryngitis and tracheitis
0.647 0.353 0.000
M45-M49 Spondylopathies
0.647 0.353 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.646 0.354 0.000
S36 Injury of intra-abdominal organs
0.646 0.354 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.646 0.354 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.646 0.354 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.646 0.354 0.000
S31 Open wound of abdomen, lower back and pelvis
0.646 0.354 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.646 0.354 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.645 0.355 0.000
T93.2 Sequelae of other fractures of lower limb
0.645 0.355 0.000
S40 Superficial injury of shoulder and upper arm
0.644 0.356 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.644 0.356 0.000
D63.0 Anaemia in neoplastic disease
0.643 0.357 0.000
S06.9 Intracranial injury, unspecified
0.643 0.357 0.000
S06.7 Intracranial injury with prolonged coma
0.643 0.357 0.000
S06.4 Epidural haemorrhage
0.643 0.357 0.000
S06.3 Focal brain injury
0.643 0.357 0.000
S06.1 Traumatic cerebral oedema
0.643 0.357 0.000
T68 Hypothermia
0.643 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.642 0.358 0.000
J20 Acute bronchitis
0.641 0.359 0.000
M53 Other dorsopathies, not elsewhere classified
0.640 0.360 0.000
S01.7 Multiple open wounds of head
0.639 0.361 0.000
S01.4 Open wound of cheek and temporomandibular area
0.639 0.361 0.000
J06.9 Acute upper respiratory infection, unspecified
0.639 0.361 0.000
M54.8 Other dorsalgia
0.638 0.362 0.000
M54.6 Pain in thoracic spine
0.638 0.362 0.000
M54.0 Panniculitis affecting regions of neck and back
0.638 0.362 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.364 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.635 0.365 0.000
I99 Other and unspecified disorders of circulatory system
0.635 0.365 0.000
R60.1 Generalised oedema
0.634 0.366 0.000
S91 Open wound of ankle and foot
0.634 0.366 0.000
R54 Senility
0.633 0.366 0.000
J21 Acute bronchiolitis
0.633 0.367 0.000
H18.9 Disorder of cornea, unspecified
0.632 0.368 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.632 0.368 0.000
H02.9 Disorder of eyelid, unspecified
0.631 0.369 0.000
J33.8 Other polyp of sinus
0.631 0.369 0.000
U51 Admission status on psychiatric patients
0.630 0.370 0.000
M54.55 Low back pain (Thoracolumbar region)
0.629 0.371 0.000
M54.54 Low back pain-Thoracic
0.629 0.371 0.000
M54.53 Low back pain-Cervicothoracic
0.629 0.371 0.000
M54.52 Low back pain-Cervical
0.629 0.371 0.000
M54.51 Low back pain-Occipit-atl-axl
0.629 0.371 0.000
S32.3 Fracture of ilium
0.628 0.372 0.000
H02.5 Other disorders affecting eyelid function
0.628 0.372 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.627 0.373 0.000
G57.5 Tarsal tunnel syndrome
0.627 0.373 0.000
G57.4 Lesion of medial popliteal nerve
0.627 0.373 0.000
G57.3 Lesion of lateral popliteal nerve
0.627 0.373 0.000
G57.2 Lesion of femoral nerve
0.627 0.373 0.000
G57.1 Meralgia paraesthetica
0.627 0.373 0.000
G57.0 Lesion of sciatic nerve
0.627 0.373 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.627 0.373 0.000
J01 Acute sinusitis
0.627 0.373 0.000
I27 Other pulmonary heart diseases
0.626 0.373 0.000
T98 Sequelae of other and unspecified effects of external causes
0.626 0.374 0.000
T95 Sequelae of burns, corrosions and frostbite
0.626 0.374 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.626 0.374 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.626 0.374 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.626 0.374 0.000
M54.9 Dorsalgia, unspecified
0.626 0.374 0.000
T88.9 Complication of surgical and medical care, unspecified
0.625 0.374 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.625 0.374 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.625 0.374 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.625 0.374 0.000
T88.2 Shock due to anaesthesia
0.625 0.374 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.625 0.374 0.000
T88.0 Infection following immunisation
0.625 0.374 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.625 0.375 0.000
T92 Sequelae of injuries of upper limb
0.624 0.375 0.000
G36 Other acute disseminated demyelination
0.624 0.376 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.624 0.376 0.000
R29.4 Clicking hip
0.624 0.376 0.000
R29.3 Abnormal posture
0.624 0.376 0.000
R29.2 Abnormal reflex
0.624 0.376 0.000
R29.1 Meningismus
0.624 0.376 0.000
R29.0 Tetany
0.624 0.376 0.000
G58.7 Mononeuritis multiplex
0.624 0.376 0.000
G58.0 Intercostal neuropathy
0.624 0.376 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.623 0.377 0.000
Q80-Q89 Other congenital malformations
0.623 0.377 0.000
Q35-Q37 Cleft lip and cleft palate
0.623 0.377 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.623 0.377 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.623 0.377 0.000
Q00-Q07 Congenital malformations of the nervous system
0.623 0.377 0.000
R82 Other abnormal findings in urine
0.623 0.377 0.000
H20 Iridocyclitis
0.623 0.377 0.000
J69 Pneumonitis due to solids and liquids
0.622 0.378 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.621 0.378 0.000
S00.1 Contusion of eyelid and periocular area
0.621 0.378 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.620 0.380 0.000
H00 Hordeolum and chalazion
0.620 0.380 0.000
S06.00 Concussion (without open intracranial wound)
0.619 0.381 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.619 0.381 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.619 0.381 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.618 0.381 0.000
H21 Other disorders of iris and ciliary body
0.618 0.381 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.618 0.381 0.000
H17 Corneal scars and opacities
0.618 0.381 0.000
H16 Keratitis
0.618 0.381 0.000
H15 Disorders of sclera
0.618 0.381 0.000
S00.8 Superficial injury of other parts of head
0.617 0.383 0.000
S82.2 Fracture of shaft of tibia
0.617 0.383 0.000
R61.1 Generalised hyperhidrosis
0.617 0.383 0.000
R61.0 Localised hyperhidrosis
0.617 0.383 0.000
S32.5 Fracture of pubis
0.616 0.384 0.000
S22.3 Fracture of rib
0.615 0.384 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.615 0.385 0.000
Q50-Q56 Congenital malformations of genital organs
0.615 0.385 0.000
S32.1 Fracture of sacrum
0.614 0.386 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.614 0.386 0.000
G44.8 Other specified headache syndromes
0.614 0.386 0.000
D50-D53 Nutritional anaemias
0.613 0.387 0.000
S32.4 Fracture of acetabulum
0.613 0.387 0.000
G40 Epilepsy
0.613 0.387 0.000
I63.8 Other cerebral infarction
0.612 0.387 0.000
G82.4 Spastic tetraplegia
0.612 0.388 0.000
G82.3 Flaccid tetraplegia
0.612 0.388 0.000
G82.0 Flaccid paraplegia
0.612 0.388 0.000
G56 Mononeuropathies of upper limb
0.612 0.388 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.611 0.389 0.000
D74 Methaemoglobinaemia
0.611 0.389 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.611 0.389 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.611 0.389 0.000
J30 Vasomotor and allergic rhinitis
0.610 0.389 0.000
G41 Status epilepticus
0.610 0.390 0.000
S92 Fracture of foot, except ankle
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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