TreeWAS – Variant ID: rs7775835

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K40 Inguinal hernia	0.000	0.001	0.999
K90 Intestinal malabsorption	0.999	0.001	0.000
M20-M25 Other joint disorders	0.999	0.001	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
N40 Hyperplasia of prostate	0.000	0.001	0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.999	0.001	0.000
Chapter VII Diseases of the eye and adnexa	0.999	0.001	0.000
Chapter XI Diseases of the digestive system	0.999	0.001	0.001
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
C15-C26 Malignant neoplasms of digestive organs	0.999	0.001	0.000
D80-D89 Certain disorders involving the immune mechanism	0.999	0.001	0.000
K70-K77 Diseases of liver	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.998	0.002	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.002	0.998
K90-K93 Other diseases of the digestive system	0.998	0.002	0.001
E27 Other disorders of adrenal gland	0.998	0.002	0.000
K44 Diaphragmatic hernia	0.000	0.003	0.997
K40-K46 Hernia	0.001	0.003	0.997
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.997	0.003	0.000
M35 Other systemic involvement of connective tissue	0.997	0.003	0.000
M35.0 Sicca syndrome [Sjogren]	0.997	0.003	0.000
K75 Other inflammatory liver diseases	0.997	0.003	0.000
D86 Sarcoidosis	0.996	0.004	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.996	0.004	0.000
H25-H28 Disorders of lens	0.996	0.004	0.000
E27.1 Primary adrenocortical insufficiency	0.996	0.004	0.000
K75.4 Autoimmune hepatitis	0.995	0.005	0.000
H26 Other cataract	0.995	0.005	0.000
E10.3 With ophthalmic complications	0.994	0.006	0.000
H26.9 Cataract, unspecified	0.994	0.006	0.000
L50-L54 Urticaria and erythema	0.991	0.009	0.000
E14 Unspecified diabetes mellitus	0.990	0.010	0.000
D86.9 Sarcoidosis, unspecified	0.989	0.011	0.000
H43-H45 Disorders of vitreous body and globe	0.988	0.012	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.012	0.988
C25 Malignant neoplasm of pancreas	0.988	0.012	0.000
E10.2 With renal complications	0.980	0.020	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.980	0.020	0.000
M15-M19 Arthrosis	0.980	0.020	0.000
H43 Disorders of vitreous body	0.979	0.021	0.000
M65-M68 Disorders of synovium and tendon	0.977	0.023	0.000
C15 Malignant neoplasm of oesophagus	0.971	0.029	0.000
M20.1 Hallux valgus (acquired)	0.000	0.031	0.969
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.969	0.031	0.000
M17 Gonarthrosis [arthrosis of knee]	0.969	0.031	0.000
M70-M79 Other soft tissue disorders	0.969	0.031	0.000
L50 Urticaria	0.968	0.032	0.000
H43.1 Vitreous haemorrhage	0.967	0.033	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.967	0.033	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.967	0.033	0.000
E14.3 With ophthalmic complications	0.966	0.034	0.000
M72 Fibroblastic disorders	0.966	0.034	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.966	0.034	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.035	0.965
M20 Acquired deformities of fingers and toes	0.002	0.043	0.955
M67 Other disorders of synovium and tendon	0.957	0.043	0.000
K72 Hepatic failure, not elsewhere classified	0.956	0.044	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.045	0.955
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.953	0.047	0.000
R39 Other symptoms and signs involving the urinary system	0.000	0.048	0.952
E10.1 With ketoacidosis	0.950	0.050	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.051	0.949
Q38-Q45 Other congenital malformations of the digestive system	0.943	0.057	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.942	0.058	0.000
C25.9 Pancreas, unspecified	0.941	0.059	0.000
H26.4 After-cataract	0.937	0.063	0.000
M67.8 Other specified disorders of synovium and tendon	0.937	0.063	0.000
M17.1 Other primary gonarthrosis	0.935	0.065	0.000
L50.9 Urticaria, unspecified	0.932	0.068	0.000
L40-L45 Papulosquamous disorders	0.930	0.070	0.000
C85.1 B-cell lymphoma, unspecified	0.928	0.072	0.000
M17.9 Gonarthrosis, unspecified	0.927	0.073	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.926	0.074	0.000
D86.0 Sarcoidosis of lung	0.923	0.077	0.000
C81 Hodgkin's disease	0.920	0.080	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.080	0.920
K73 Chronic hepatitis, not elsewhere classified	0.918	0.082	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.912	0.088	0.000
L52 Erythema nodosum	0.902	0.098	0.000
K72.9 Hepatic failure, unspecified	0.901	0.099	0.000
L43 Lichen planus	0.897	0.103	0.000
E13 Other specified diabetes mellitus	0.896	0.104	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.895	0.105	0.000
M24 Other specific joint derangements	0.895	0.105	0.000
C15.4 Middle third of oesophagus	0.894	0.106	0.000
C25.3 Pancreatic duct	0.892	0.108	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.891	0.109	0.000
Chapter XX External causes of morbidity and mortality	0.891	0.109	0.000
N40-N51 Diseases of male genital organs	0.000	0.110	0.890
M05-M14 Inflammatory polyarthropathies	0.889	0.111	0.000
E10.4 With neurological complications	0.888	0.112	0.000
M34 Systemic sclerosis	0.884	0.116	0.000
L10-L14 Bullous disorders	0.879	0.120	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.879	0.121	0.000
L43.9 Lichen planus, unspecified	0.879	0.121	0.000
D61 Other aplastic anaemias	0.873	0.127	0.000
M18 Arthrosis of first carpometacarpal joint	0.873	0.127	0.000
E50-E64 Other nutritional deficiencies	0.871	0.129	0.000
N42 Other disorders of prostate	0.000	0.129	0.871
D00-D09 In situ neoplasms	0.871	0.129	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.869	0.131	0.000
H30-H36 Disorders of choroid and retina	0.863	0.137	0.000
L53 Other erythematous conditions	0.858	0.142	0.000
C04 Malignant neoplasm of floor of mouth	0.858	0.142	0.000
M60-M63 Disorders of muscles	0.856	0.144	0.000
E24 Cushing's syndrome	0.855	0.145	0.000
K35-K38 Diseases of appendix	0.855	0.145	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.854	0.146	0.000
V20-V29 Motorcycle rider injured in transport accident	0.851	0.149	0.000
Q50-Q56 Congenital malformations of genital organs	0.851	0.149	0.000
H53-H54 Visual disturbances and blindness	0.850	0.150	0.000
E20 Hypoparathyroidism	0.846	0.154	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.846	0.154	0.000
H27 Other disorders of lens	0.846	0.154	0.000
K75.8 Other specified inflammatory liver diseases	0.842	0.158	0.000
C34 Malignant neoplasm of bronchus and lung	0.841	0.159	0.000
M76 Enthesopathies of lower limb, excluding foot	0.841	0.159	0.000
L50.0 Allergic urticaria	0.840	0.160	0.000
E14.9 Without complications	0.839	0.161	0.000
D83 Common variable immunodeficiency	0.839	0.161	0.000
K46 Unspecified abdominal hernia	0.000	0.162	0.837
G35 Multiple sclerosis	0.837	0.163	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.836	0.164	0.000
Chapter VI Diseases of the nervous system	0.834	0.166	0.000
L89 Decubitus ulcer	0.833	0.167	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.832	0.168	0.000
M22 Disorders of patella	0.832	0.168	0.000
W20-W49 Exposure to inanimate mechanical forces	0.831	0.169	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.831	0.169	0.000
N42.8 Other specified disorders of prostate	0.000	0.178	0.822
L97 Ulcer of lower limb, not elsewhere classified	0.822	0.178	0.000
E13.9 Without complications	0.822	0.178	0.000
K90.9 Intestinal malabsorption, unspecified	0.821	0.179	0.000
C15.3 Upper third of oesophagus	0.820	0.180	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.001	0.184	0.815
D06 Carcinoma in situ of cervix uteri	0.814	0.186	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.813	0.187	0.000
Q43 Other congenital malformations of intestine	0.812	0.188	0.000
K35 Acute appendicitis	0.812	0.188	0.000
M23 Internal derangement of knee	0.812	0.188	0.000
H54 Blindness and low vision	0.812	0.188	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.812	0.188	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.811	0.189	0.000
M07 Psoriatic and enteropathic arthropathies	0.810	0.190	0.000
E10.7 With multiple complications	0.810	0.190	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.810	0.190	0.000
C07 Malignant neoplasm of parotid gland	0.810	0.190	0.000
K72.0 Acute and subacute hepatic failure	0.809	0.191	0.000
K35.9 Acute appendicitis, unspecified	0.808	0.192	0.000
H26.1 Traumatic cataract	0.805	0.195	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.805	0.195	0.000
L94 Other localised connective tissue disorders	0.803	0.197	0.000
C34.3 Lower lobe, bronchus or lung	0.800	0.200	0.000
C15.0 Cervical part of oesophagus	0.799	0.201	0.000
C15.9 Oesophagus, unspecified	0.799	0.201	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.799	0.201	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.798	0.202	0.000
H43.8 Other disorders of vitreous body	0.798	0.202	0.000
Q44.6 Cystic disease of liver	0.798	0.202	0.000
C16 Malignant neoplasm of stomach	0.797	0.203	0.000
E10.5 With peripheral circulatory complications	0.796	0.204	0.000
C25.1 Body of pancreas	0.794	0.206	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.792	0.208	0.000
K73.9 Chronic hepatitis, unspecified	0.792	0.208	0.000
E10.0 With coma	0.789	0.211	0.000
M11 Other crystal arthropathies	0.787	0.213	0.000
W22 Striking against or struck by other objects	0.787	0.213	0.000
C18 Malignant neoplasm of colon	0.786	0.214	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.786	0.214	0.000
V23.4 Driver injured in traffic accident	0.786	0.214	0.000
N41 Inflammatory diseases of prostate	0.000	0.214	0.786
D80 Immunodeficiency with predominantly antibody defects	0.784	0.216	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.783	0.216	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.781	0.219	0.000
C13 Malignant neoplasm of hypopharynx	0.780	0.220	0.000
M15 Polyarthrosis	0.777	0.223	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.777	0.223	0.000
C84.5 Other and unspecified T-cell lymphomas	0.775	0.225	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.225	0.775
H36 Retinal disorders in diseases classified elsewhere	0.774	0.225	0.000
D06.9 Cervix, unspecified	0.774	0.226	0.000
C23 Malignant neoplasm of gallbladder	0.773	0.227	0.000
D86.8 Sarcoidosis of other and combined sites	0.773	0.227	0.000
H46 Optic neuritis	0.773	0.227	0.000
C84.0 Mycosis fungoides	0.772	0.228	0.000
H34 Retinal vascular occlusions	0.772	0.228	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.771	0.229	0.000
D61.9 Aplastic anaemia, unspecified	0.769	0.231	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.769	0.231	0.000
C25.2 Tail of pancreas	0.768	0.231	0.000
M31 Other necrotising vasculopathies	0.768	0.232	0.000
C81.9 Hodgkin's disease, unspecified	0.765	0.235	0.000
D55-D59 Haemolytic anaemias	0.765	0.235	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.238	0.762
C95 Leukaemia of unspecified cell type	0.762	0.238	0.000
L20-L30 Dermatitis and eczema	0.762	0.238	0.000
K90.8 Other intestinal malabsorption	0.761	0.238	0.000
H44 Disorders of globe	0.759	0.241	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.758	0.242	0.000
X20-X29 Contact with venomous animals and plants	0.756	0.244	0.000
E14.6 With other specified complications	0.756	0.244	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.756	0.244	0.000
M10 Gout	0.755	0.245	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.245	0.755
M07.3 Other psoriatic arthropathies	0.754	0.246	0.000
K75.9 Inflammatory liver disease, unspecified	0.754	0.246	0.000
M34.1 CR(E)ST syndrome	0.754	0.246	0.000
E53 Deficiency of other B group vitamins	0.753	0.247	0.000
M62 Other disorders of muscle	0.752	0.248	0.000
E14.5 With peripheral circulatory complications	0.752	0.248	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.248	0.752
C81.2 Mixed cellularity	0.751	0.249	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.750	0.250	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.750	0.250	0.000
Q45 Other congenital malformations of digestive system	0.749	0.251	0.000
C43 Malignant melanoma of skin	0.749	0.251	0.000
D84 Other immunodeficiencies	0.749	0.251	0.000
L13 Other bullous disorders	0.747	0.253	0.000
M91-M94 Chondropathies	0.746	0.253	0.000
C04.0 Anterior floor of mouth	0.745	0.255	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.744	0.256	0.000
E14.8 With unspecified complications	0.744	0.256	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.743	0.257	0.000
C81.0 Lymphocytic predominance	0.743	0.257	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.743	0.257	0.000
L84 Corns and callosities	0.743	0.257	0.000
N48 Other disorders of penis	0.000	0.258	0.742
Q44.5 Other congenital malformations of bile ducts	0.741	0.259	0.000
Chapter IX Diseases of the circulatory system	0.741	0.259	0.000
C18.9 Colon, unspecified	0.741	0.259	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.741	0.259	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.740	0.260	0.000
M67.4 Ganglion	0.739	0.261	0.000
Q40 Other congenital malformations of upper alimentary tract	0.739	0.261	0.000
K74 Fibrosis and cirrhosis of liver	0.739	0.261	0.000
H47.2 Optic atrophy	0.738	0.262	0.000
W50-W64 Exposure to animate mechanical forces	0.738	0.262	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.738	0.262	0.000
M67.0 Short Achilles tendon (acquired)	0.738	0.262	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.263	0.737
M66 Spontaneous rupture of synovium and tendon	0.737	0.263	0.000
E20.9 Hypoparathyroidism, unspecified	0.736	0.264	0.000
M22.3 Other derangements of patella	0.736	0.264	0.000
M00-M03 Infectious arthropathies	0.736	0.264	0.000
L93 Lupus erythematosus	0.735	0.265	0.000
C03 Malignant neoplasm of gum	0.734	0.266	0.000
L50.1 Idiopathic urticaria	0.732	0.268	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.732	0.268	0.000
C25.0 Head of pancreas	0.730	0.269	0.000
C83.3 Large cell (diffuse)	0.730	0.270	0.000
M76.6 Achilles tendinitis	0.730	0.270	0.000
E16.1 Other hypoglycaemia	0.730	0.270	0.000
D86.3 Sarcoidosis of skin	0.729	0.270	0.000
H54.4 Blindness, one eye	0.729	0.271	0.000
E21.3 Hyperparathyroidism, unspecified	0.727	0.273	0.000
E14.4 With neurological complications	0.727	0.273	0.000
M32 Systemic lupus erythematosus	0.727	0.273	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.274	0.726
H43.2 Crystalline deposits in vitreous body	0.726	0.274	0.000
M65 Synovitis and tenosynovitis	0.726	0.274	0.000
D83.9 Common variable immunodeficiency, unspecified	0.725	0.275	0.000
E14.1 With ketoacidosis	0.723	0.277	0.000
C05 Malignant neoplasm of palate	0.723	0.277	0.000
V01-V09 Pedestrian injured in transport accident	0.722	0.278	0.000
H43.9 Disorder of vitreous body, unspecified	0.721	0.279	0.000
H34.8 Other retinal vascular occlusions	0.721	0.279	0.000
E23 Hypofunction and other disorders of pituitary gland	0.721	0.279	0.000
E24.2 Drug-induced Cushing's syndrome	0.719	0.281	0.000
D04 Carcinoma in situ of skin	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.283	0.717
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.283	0.717
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.716	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.716	0.283	0.000
K90.1 Tropical sprue	0.716	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.716	0.284	0.000
C94 Other leukaemias of specified cell type	0.716	0.284	0.000
C86 Other specified types of T/NK-cell lymphoma	0.716	0.284	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.284	0.716
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E31 Polyglandular dysfunction	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
D82 Immunodeficiency associated with other major defects	0.716	0.284	0.000
D81 Combined immunodeficiencies	0.716	0.284	0.000
K77 Liver disorders in diseases classified elsewhere	0.716	0.284	0.000
K71 Toxic liver disease	0.716	0.284	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.715	0.284	0.001
E27.5 Adrenomedullary hyperfunction	0.715	0.284	0.000
E27.0 Other adrenocortical overactivity	0.715	0.284	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.715	0.285	0.000
K44.1 Diaphragmatic hernia with gangrene	0.000	0.285	0.715
C85.0 Lymphosarcoma	0.715	0.285	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.715	0.285	0.000
M35.8 Other specified systemic involvement of connective tissue	0.715	0.285	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.715	0.285	0.000
M35.5 Multifocal fibrosclerosis	0.715	0.285	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.715	0.285	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.715	0.285	0.000
K75.2 Nonspecific reactive hepatitis	0.715	0.285	0.000
K75.1 Phlebitis of portal vein	0.715	0.285	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.714	0.285	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.714	0.286	0.000
M11.2 Other chondrocalcinosis	0.714	0.286	0.000
H26.3 Drug-induced cataract	0.713	0.286	0.000
I77 Other disorders of arteries and arterioles	0.713	0.287	0.000
E24.0 Pituitary-dependent Cushing's disease	0.712	0.288	0.000
M17.3 Other posttraumatic gonarthrosis	0.711	0.289	0.000
H36.0 Diabetic retinopathy	0.711	0.289	0.000
L54 Erythema in diseases classified elsewhere	0.711	0.289	0.000
N48.1 Balanoposthitis	0.000	0.289	0.711
E14.7 With multiple complications	0.710	0.290	0.000
E14.2 Withrenal complications	0.710	0.290	0.000
E14.0 With coma	0.710	0.290	0.000
C04.9 Floor of mouth, unspecified	0.710	0.290	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.709	0.291	0.000
Q39 Congenital malformations of oesophagus	0.708	0.292	0.000
C25.8 Overlapping lesion of pancreas	0.708	0.292	0.000
C25.7 Other parts of pancreas	0.708	0.292	0.000
C25.4 Endocrine pancreas	0.708	0.292	0.000
C81.1 Nodular sclerosis	0.707	0.293	0.000
H43.3 Other vitreous opacities	0.706	0.294	0.000
L11 Other acantholytic disorders	0.705	0.295	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.704	0.296	0.000
E27.2 Addisonian crisis	0.703	0.296	0.000
I73 Other peripheral vascular diseases	0.703	0.297	0.000
E10.8 With unspecified complications	0.703	0.297	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.703	0.297	0.000
H43.0 Vitreous prolapse	0.702	0.298	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.702	0.298	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.701	0.299	0.000
E40-E46 Malnutrition	0.701	0.299	0.000
E10.6 With other specified complications	0.699	0.301	0.000
E03.8 Other specified hypothyroidism	0.699	0.301	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.698	0.301	0.000
M33 Dermatopolymyositis	0.698	0.302	0.000
C60-C63 Malignant neoplasms of male genital organs	0.698	0.302	0.000
M35.1 Other overlap syndromes	0.697	0.303	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.697	0.303	0.000
I74 Arterial embolism and thrombosis	0.697	0.303	0.000
C15.8 Overlapping lesion of oesophagus	0.696	0.303	0.000
C15.2 Abdominal part of oesophagus	0.696	0.303	0.000
C15.1 Thoracic part of oesophagus	0.696	0.303	0.000
C01 Malignant neoplasm of base of tongue	0.696	0.304	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.696	0.304	0.000
C17 Malignant neoplasm of small intestine	0.696	0.304	0.000
C11 Malignant neoplasm of nasopharynx	0.696	0.304	0.000
C93 Monocytic leukaemia	0.695	0.305	0.000
Q35-Q37 Cleft lip and cleft palate	0.695	0.305	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.695	0.305	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.695	0.305	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.695	0.305	0.000
L89.2 Stage III decubitus ulcer	0.695	0.305	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.695	0.305	0.000
M34.8 Other forms of systemic sclerosis	0.694	0.305	0.000
K41 Femoral hernia	0.000	0.306	0.694
H54.7 Unspecified visual loss	0.694	0.306	0.000
L50.6 Contact urticaria	0.694	0.306	0.000
L50.5 Cholinergic urticaria	0.694	0.306	0.000
L50.4 Vibratory urticaria	0.694	0.306	0.000
L50.3 Dermatographic urticaria	0.694	0.306	0.000
L50.2 Urticaria due to cold and heat	0.694	0.306	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.694	0.306	0.000
M35.7 Hypermobility syndrome	0.693	0.306	0.000
W45 Foreign body or object entering through skin	0.693	0.306	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.693	0.307	0.000
Q00-Q07 Congenital malformations of the nervous system	0.693	0.307	0.000
M72.9 Fibroblastic disorder, unspecified	0.693	0.307	0.000
M72.8 Other fibroblastic disorders	0.693	0.307	0.000
M72.6 Necrotizing fasciitis	0.693	0.307	0.000
M72.5 Fasciitis, not elsewhere classified	0.693	0.307	0.000
M72.4 Pseudosarcomatous fibromatosis	0.693	0.307	0.000
M72.3 Nodular fasciitis	0.693	0.307	0.000
M72.1 Knuckle pads	0.693	0.307	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.693	0.307	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.693	0.307	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.693	0.307	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.693	0.307	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.693	0.307	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.693	0.307	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.693	0.307	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.693	0.307	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.693	0.307	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.693	0.307	0.000
M24.2 Disorder of ligament	0.692	0.308	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.308	0.692
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.692	0.308	0.000
L51 Erythema multiforme	0.692	0.308	0.000
L53.9 Erythematous condition, unspecified	0.692	0.308	0.000
D09 Carcinoma in situ of other and unspecified sites	0.688	0.312	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.688	0.312	0.000
M71 Other bursopathies	0.688	0.312	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.687	0.313	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.686	0.314	0.000
M67.3 Transient synovitis	0.686	0.314	0.000
K72.1 Chronic hepatic failure	0.686	0.314	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.685	0.315	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.683	0.317	0.000
C00 Malignant neoplasm of lip	0.683	0.317	0.000
N46 Male infertility	0.000	0.317	0.683
R39.2 Extrarenal uraemia	0.000	0.317	0.683
N42.2 Atrophy of prostate	0.000	0.318	0.682
H27.0 Aphakia	0.682	0.318	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.682	0.318	0.000
E21.0 Primary hyperparathyroidism	0.682	0.318	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.682	0.318	0.000
G70-G73 Diseases of myoneural junction and muscle	0.681	0.319	0.000
N48.4 Impotence of organic origin	0.000	0.319	0.681
D86.1 Sarcoidosis of lymph nodes	0.681	0.319	0.000
E53.8 Deficiency of other specified B group vitamins	0.680	0.320	0.000
C88 Malignant immunoproliferative diseases	0.679	0.320	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.321	0.679
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.679	0.321	0.000
L30 Other dermatitis	0.678	0.322	0.000
C02.9 Tongue, unspecified	0.676	0.324	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.676	0.324	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.676	0.324	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.676	0.324	0.000
M30 Polyarteritis nodosa and related conditions	0.676	0.324	0.000
H31 Other disorders of choroid	0.676	0.324	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.676	0.324	0.000
Q43.8 Other specified congenital malformations of intestine	0.675	0.324	0.000
M34.9 Systemic sclerosis, unspecified	0.675	0.325	0.000
L80 Vitiligo	0.674	0.326	0.000
D62 Acute posthaemorrhagic anaemia	0.674	0.326	0.000
L53.0 Toxic erythema	0.674	0.326	0.000
H47.3 Other disorders of optic disk	0.674	0.326	0.000
H27.8 Other specified disorders of lens	0.674	0.326	0.000
L53.8 Other specified erythematous conditions	0.674	0.326	0.000
E34 Other endocrine disorders	0.673	0.327	0.000
Q43.3 Congenital malformations of intestinal fixation	0.672	0.328	0.000
E06 Thyroiditis	0.672	0.328	0.000
I60-I69 Cerebrovascular diseases	0.672	0.328	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.672	0.328	0.000
Q53 Undescended testicle	0.671	0.329	0.000
W22.9 Unspecified place	0.670	0.330	0.000
E27.9 Disorder of adrenal gland, unspecified	0.669	0.331	0.000
I73.9 Peripheral vascular disease, unspecified	0.669	0.331	0.000
W22.3 Sports and athletics area	0.668	0.332	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.668	0.332	0.000
M24.5 Contracture of joint	0.667	0.332	0.000
X00-X09 Exposure to smoke, fire and flames	0.667	0.332	0.000
C34.0 Main bronchus	0.667	0.333	0.000
L44 Other papulosquamous disorders	0.667	0.333	0.000
L41 Parapsoriasis	0.667	0.333	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.667	0.333	0.000
L94.2 Calcinosis cutis	0.666	0.334	0.000
Q51 Congenital malformations of uterus and cervix	0.665	0.335	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.664	0.336	0.000
M17.0 Primary gonarthrosis, bilateral	0.663	0.337	0.000
E55 Vitamin D deficiency	0.662	0.338	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations