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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7776351
log Bayes Factor = 84.9325
Chromosome 6   position 27,726,731  (GRCh37) Explore rs7776351 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.001 0.999
R31 Unspecified haematuria
0.000 0.004 0.996
K40 Inguinal hernia
0.000 0.009 0.991
E14 Unspecified diabetes mellitus
0.990 0.010 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.988 0.012 0.000
E16 Other disorders of pancreatic internal secretion
0.980 0.020 0.000
N40-N51 Diseases of male genital organs
0.000 0.025 0.975
E16.2 Hypoglycaemia, unspecified
0.974 0.026 0.000
N41 Inflammatory diseases of prostate
0.000 0.027 0.973
E20-E35 Disorders of other endocrine glands
0.964 0.036 0.000
N45 Orchitis and epididymitis
0.000 0.046 0.954
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.057 0.943
E23 Hypofunction and other disorders of pituitary gland
0.943 0.057 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.058 0.942
N41.1 Chronic prostatitis
0.000 0.071 0.929
E14.3 With ophthalmic complications
0.918 0.082 0.000
E10.3 With ophthalmic complications
0.912 0.088 0.000
E14.9 Without complications
0.907 0.093 0.000
E10.2 With renal complications
0.899 0.101 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.898 0.102 0.000
N41.0 Acute prostatitis
0.000 0.109 0.891
E23.2 Diabetes insipidus
0.889 0.111 0.000
E10.1 With ketoacidosis
0.878 0.122 0.000
E07 Other disorders of thyroid
0.868 0.132 0.000
E10.6 With other specified complications
0.858 0.142 0.000
E23.0 Hypopituitarism
0.838 0.162 0.000
E14.4 With neurological complications
0.834 0.166 0.000
E21.3 Hyperparathyroidism, unspecified
0.829 0.171 0.000
N46 Male infertility
0.000 0.176 0.824
E10.4 With neurological complications
0.824 0.176 0.000
E14.6 With other specified complications
0.822 0.178 0.000
E10.7 With multiple complications
0.818 0.182 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.812 0.188 0.000
N42 Other disorders of prostate
0.000 0.210 0.790
E21.0 Primary hyperparathyroidism
0.781 0.219 0.000
E10.0 With coma
0.779 0.221 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.777 0.223 0.000
K90 Intestinal malabsorption
0.767 0.232 0.000
N44 Torsion of testis
0.000 0.250 0.750
N42.8 Other specified disorders of prostate
0.000 0.257 0.743
E16.0 Drug-induced hypoglycaemia without coma
0.742 0.258 0.000
E14.2 Withrenal complications
0.741 0.259 0.000
E07.9 Disorder of thyroid, unspecified
0.740 0.260 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.738 0.262 0.000
E23.7 Disorder of pituitary gland, unspecified
0.731 0.269 0.000
E14.8 With unspecified complications
0.730 0.270 0.000
E31 Polyglandular dysfunction
0.722 0.277 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.279 0.721
E20 Hypoparathyroidism
0.720 0.280 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E24 Cushing's syndrome
0.713 0.286 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.712 0.288 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.290 0.710
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.290 0.710
E14.7 With multiple complications
0.710 0.290 0.000
E14.0 With coma
0.710 0.290 0.000
E15 Nondiabetic hypoglycaemic coma
0.709 0.291 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.707 0.293 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.703 0.297 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.703 0.297 0.000
E16.4 Abnormal secretion of gastrin
0.703 0.297 0.000
E16.3 Increased secretion of glucagon
0.703 0.297 0.000
E16.1 Other hypoglycaemia
0.700 0.300 0.000
N41.3 Prostatocystitis
0.000 0.302 0.698
N41.2 Abscess of prostate
0.000 0.302 0.698
E23.6 Other disorders of pituitary gland
0.694 0.306 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.691 0.309 0.000
E32 Diseases of thymus
0.691 0.309 0.000
E30 Disorders of puberty, not elsewhere classified
0.691 0.309 0.000
E34 Other endocrine disorders
0.689 0.310 0.000
E07.8 Other specified disorders of thyroid
0.686 0.314 0.000
E10.5 With peripheral circulatory complications
0.686 0.314 0.000
E25 Adrenogenital disorders
0.681 0.319 0.000
E10.8 With unspecified complications
0.678 0.321 0.000
E13 Other specified diabetes mellitus
0.676 0.324 0.000
E21.2 Other hyperparathyroidism
0.676 0.324 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.676 0.324 0.000
E23.1 Drug-induced hypopituitarism
0.676 0.324 0.000
E03.8 Other specified hypothyroidism
0.671 0.329 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.337 0.663
E14.1 With ketoacidosis
0.660 0.340 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.355 0.645
E21.4 Other specified disorders of parathyroid gland
0.644 0.356 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.632 0.368 0.000
E40-E46 Malnutrition
0.631 0.369 0.000
E28 Ovarian dysfunction
0.627 0.373 0.000
E07.1 Dyshormogenetic goitre
0.622 0.378 0.000
E07.0 Hypersecretion of calcitonin
0.622 0.378 0.000
E29 Testicular dysfunction
0.603 0.397 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.599 0.401 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.407 0.593
E06 Thyroiditis
0.589 0.411 0.000
E27 Other disorders of adrenal gland
0.583 0.417 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.420 0.580
E24.2 Drug-induced Cushing's syndrome
0.572 0.428 0.000
N42.0 Calculus of prostate
0.000 0.429 0.571
N42.3 Dysplasia of prostate
0.000 0.433 0.567
E53 Deficiency of other B group vitamins
0.555 0.445 0.000
K90.3 Pancreatic steatorrhoea
0.550 0.449 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.550 0.449 0.000
K90.1 Tropical sprue
0.550 0.449 0.000
E31.0 Autoimmune polyglandular failure
0.549 0.451 0.000
E20.9 Hypoparathyroidism, unspecified
0.545 0.455 0.000
E26 Hyperaldosteronism
0.536 0.463 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.531 0.468 0.000
E34.8 Other specified endocrine disorders
0.531 0.469 0.000
E13.3 With ophthalmic complications
0.530 0.470 0.000
E05.8 Other thyrotoxicosis
0.529 0.471 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.471 0.529
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.527 0.472 0.000
K90.8 Other intestinal malabsorption
0.523 0.477 0.000
E27.1 Primary adrenocortical insufficiency
0.521 0.479 0.000
E31.9 Polyglandular dysfunction, unspecified
0.518 0.482 0.000
E31.8 Other polyglandular dysfunction
0.518 0.482 0.000
E31.1 Polyglandular hyperfunction
0.518 0.482 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.483 0.517
E20.8 Other hypoparathyroidism
0.516 0.483 0.000
E20.1 Pseudohypoparathyroidism
0.516 0.483 0.000
E20.0 Idiopathic hypoparathyroidism
0.516 0.483 0.000
E24.0 Pituitary-dependent Cushing's disease
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E24.8 Other Cushing's syndrome
0.512 0.488 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.512 0.488 0.000
E24.3 Ectopic ACTH syndrome
0.512 0.488 0.000
E24.1 Nelson's syndrome
0.512 0.488 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.492 0.508
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.492 0.508
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.492 0.508
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.492 0.508
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.498 0.502
E53.8 Deficiency of other specified B group vitamins
0.497 0.503 0.000
E34.9 Endocrine disorder, unspecified
0.497 0.503 0.000
E30.9 Disorder of puberty, unspecified
0.496 0.504 0.000
E30.8 Other disorders of puberty
0.496 0.504 0.000
E30.1 Precocious puberty
0.496 0.504 0.000
E30.0 Delayed puberty
0.496 0.504 0.000
E32.9 Disease of thymus, unspecified
0.496 0.504 0.000
E32.8 Other diseases of thymus
0.496 0.504 0.000
E32.1 Abscess of thymus
0.496 0.504 0.000
E32.0 Persistent hyperplasia of thymus
0.496 0.504 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.496 0.504 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.496 0.504 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.496 0.504 0.000
E34.5 Androgen resistance syndrome
0.494 0.505 0.000
E34.4 Constitutional tall stature
0.494 0.505 0.000
E34.3 Short stature, not elsewhere classified
0.494 0.505 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.494 0.505 0.000
E34.1 Other hypersecretion of intestinal hormones
0.494 0.505 0.000
E25.9 Adrenogenital disorder, unspecified
0.488 0.511 0.000
E25.8 Other adrenogenital disorders
0.488 0.511 0.000
E58 Dietary calcium deficiency
0.488 0.512 0.000
E13.8 With unspecified complications
0.485 0.515 0.000
E13.7 With multiple complications
0.485 0.515 0.000
E13.6 With other specified complications
0.485 0.515 0.000
E13.5 With peripheral circulatory complications
0.485 0.515 0.000
E13.4 With neurological complications
0.485 0.515 0.000
E13.2 With renal complications
0.485 0.515 0.000
E13.1 With ketoacidosis
0.485 0.515 0.000
E13.0 With coma
0.485 0.515 0.000
E22 Hyperfunction of pituitary gland
0.481 0.519 0.000
E28.3 Primary ovarian failure
0.481 0.519 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.478 0.521 0.000
E51 Thiamine deficiency
0.478 0.522 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.478 0.522 0.000
E63 Other nutritional deficiencies
0.478 0.522 0.000
E56 Other vitamin deficiencies
0.478 0.522 0.000
E50 Vitamin A deficiency
0.478 0.522 0.000
E60 Dietary zinc deficiency
0.478 0.522 0.000
E59 Dietary selenium deficiency
0.478 0.522 0.000
E54 Ascorbic acid deficiency
0.478 0.522 0.000
E52 Niacin deficiency [pellagra]
0.478 0.522 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.525 0.475
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.525 0.475
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.525 0.475
E44 Protein-energy malnutrition of moderate and mild degree
0.452 0.548 0.000
E45 Retarded development following protein-energy malnutrition
0.452 0.548 0.000
E43 Unspecified severe protein-energy malnutrition
0.452 0.548 0.000
E42 Marasmic kwashiorkor
0.452 0.548 0.000
E41 Nutritional marasmus
0.452 0.548 0.000
E40 Kwashiorkor
0.452 0.548 0.000
E24.9 Cushing's syndrome, unspecified
0.452 0.548 0.000
E11 Non-insulin-dependent diabetes mellitus
0.451 0.549 0.000
E28.9 Ovarian dysfunction, unspecified
0.449 0.551 0.000
E28.8 Other ovarian dysfunction
0.449 0.551 0.000
E28.1 Androgen excess
0.449 0.551 0.000
E28.0 Oestrogen excess
0.449 0.551 0.000
E34.0 Carcinoid syndrome
0.444 0.556 0.000
K90.9 Intestinal malabsorption, unspecified
0.436 0.564 0.000
E29.9 Testicular dysfunction, unspecified
0.432 0.568 0.000
E29.8 Other testicular dysfunction
0.432 0.568 0.000
E29.0 Testicular hyperfunction
0.432 0.568 0.000
E06.9 Thyroiditis, unspecified
0.432 0.568 0.000
E06.5 Other chronic thyroiditis
0.422 0.577 0.000
E06.4 Drug-induced thyroiditis
0.422 0.577 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.422 0.577 0.000
E06.1 Subacute thyroiditis
0.422 0.577 0.000
E06.0 Acute thyroiditis
0.422 0.577 0.000
E27.9 Disorder of adrenal gland, unspecified
0.421 0.579 0.000
E11.5 With peripheral circulatory complications
0.421 0.579 0.000
E27.5 Adrenomedullary hyperfunction
0.418 0.582 0.000
E27.0 Other adrenocortical overactivity
0.418 0.582 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.412 0.587 0.000
E11.3 With ophthalmic complications
0.407 0.593 0.000
E22.1 Hyperprolactinaemia
0.403 0.597 0.000
N42.2 Atrophy of prostate
0.000 0.598 0.402
N49.2 Inflammatory disorders of scrotum
0.000 0.598 0.401
E53.1 Pyridoxine deficiency
0.398 0.602 0.000
E53.0 Riboflavin deficiency
0.398 0.602 0.000
E55 Vitamin D deficiency
0.389 0.611 0.000
E26.9 Hyperaldosteronism, unspecified
0.385 0.615 0.000
E26.8 Other hyperaldosteronism
0.385 0.615 0.000
E26.1 Secondary hyperaldosteronism
0.385 0.615 0.000
E11.6 With other specified complications
0.383 0.617 0.000
E27.2 Addisonian crisis
0.381 0.619 0.000
E13.9 Without complications
0.374 0.626 0.000
E61 Deficiency of other nutrient elements
0.374 0.626 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.371 0.628 0.000
E46 Unspecified protein-energy malnutrition
0.366 0.634 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.345 0.655 0.000
E22.8 Other hyperfunction of pituitary gland
0.345 0.655 0.000
E29.1 Testicular hypofunction
0.344 0.656 0.000
E51.2 Wernicke's encephalopathy
0.343 0.657 0.000
E51.9 Thiamine deficiency, unspecified
0.343 0.657 0.000
E51.8 Other manifestations of thiamine deficiency
0.343 0.657 0.000
E51.1 Beriberi
0.343 0.657 0.000
E50.9 Vitamin A deficiency, unspecified
0.343 0.657 0.000
E50.8 Other manifestations of vitamin A deficiency
0.343 0.657 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.343 0.657 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.343 0.657 0.000
E50.5 Vitamin A deficiency with night blindness
0.343 0.657 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.343 0.657 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.343 0.657 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.343 0.657 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.343 0.657 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.343 0.657 0.000
E56.9 Vitamin deficiency, unspecified
0.343 0.657 0.000
E56.8 Deficiency of other vitamins
0.343 0.657 0.000
E56.1 Deficiency of vitamin K
0.343 0.657 0.000
E56.0 Deficiency of vitamin E
0.343 0.657 0.000
E63.9 Nutritional deficiency, unspecified
0.343 0.657 0.000
E63.8 Other specified nutritional deficiencies
0.343 0.657 0.000
E63.1 Imbalance of constituents of food intake
0.343 0.657 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.343 0.657 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.343 0.657 0.000
E64.8 Sequelae of other nutritional deficiencies
0.343 0.657 0.000
E64.3 Sequelae of rickets
0.343 0.657 0.000
E64.2 Sequelae of vitamin C deficiency
0.343 0.657 0.000
E64.1 Sequelae of vitamin A deficiency
0.343 0.657 0.000
E64.0 Sequelae of protein-energy malnutrition
0.343 0.657 0.000
E53.9 Vitamin B deficiency, unspecified
0.341 0.659 0.000
N43 Hydrocele and spermatocele
0.000 0.661 0.339
E65-E68 Obesity and other hyperalimentation
0.335 0.665 0.000
E28.2 Polycystic ovarian syndrome
0.332 0.668 0.000
E44.1 Mild protein-energy malnutrition
0.324 0.675 0.000
E44.0 Moderate protein-energy malnutrition
0.324 0.675 0.000
E11.7 With multiple complications
0.323 0.676 0.000
E11.0 With coma
0.319 0.681 0.000
K40-K46 Hernia
0.000 0.716 0.284
E55.0 Rickets, active
0.279 0.721 0.000
K44 Diaphragmatic hernia
0.000 0.723 0.277
E06.3 Autoimmune thyroiditis
0.276 0.724 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.728 0.272
E61.9 Deficiency of nutrient element, unspecified
0.268 0.732 0.000
E61.8 Deficiency of other specified nutrient elements
0.268 0.732 0.000
E61.7 Deficiency of multiple nutrient elements
0.268 0.732 0.000
E61.6 Vanadium deficiency
0.268 0.732 0.000
E61.5 Molybdenum deficiency
0.268 0.732 0.000
E61.4 Chromium deficiency
0.268 0.732 0.000
E61.3 Manganese deficiency
0.268 0.732 0.000
E61.0 Copper deficiency
0.268 0.732 0.000
E11.8 With unspecified complications
0.265 0.734 0.000
E11.1 With ketoacidosis
0.245 0.755 0.000
N43.2 Other hydrocele
0.000 0.757 0.243
N43.1 Infected hydrocele
0.000 0.757 0.243
N43.0 Encysted hydrocele
0.000 0.757 0.243
E67 Other hyperalimentation
0.240 0.760 0.000
E68 Sequelae of hyperalimentation
0.240 0.760 0.000
E61.1 Iron deficiency
0.231 0.769 0.000
E26.0 Primary hyperaldosteronism
0.230 0.769 0.001
N42.9 Disorder of prostate, unspecified
0.000 0.777 0.223
E61.2 Magnesium deficiency
0.218 0.781 0.000
E22.0 Acromegaly and pituitary gigantism
0.209 0.790 0.001
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.793 0.207
K44.1 Diaphragmatic hernia with gangrene
0.000 0.801 0.199
K41 Femoral hernia
0.000 0.808 0.192
N43.4 Spermatocele
0.000 0.808 0.191
E55.9 Vitamin D deficiency, unspecified
0.189 0.810 0.000
K46 Unspecified abdominal hernia
0.000 0.815 0.185
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.178 0.822 0.001
E65 Localised adiposity
0.176 0.824 0.000
E67.8 Other specified hyperalimentation
0.172 0.827 0.000
E67.3 Hypervitaminosis D
0.172 0.827 0.000
E67.2 Megavitamin-B6 syndrome
0.172 0.827 0.000
E67.1 Hypercarotenaemia
0.172 0.827 0.000
E67.0 Hypervitaminosis A
0.172 0.827 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.839 0.161
N50 Other disorders of male genital organs
0.000 0.843 0.157
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.859 0.141
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.862 0.138
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.862 0.138
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.862 0.138
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.862 0.138
E27.8 Other specified disorders of adrenal gland
0.131 0.865 0.003
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.867 0.133
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.872 0.128
K42 Umbilical hernia
0.000 0.878 0.122
E11.2 With renal complications
0.121 0.878 0.001
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.881 0.118
N50.9 Disorder of male genital organs, unspecified
0.000 0.882 0.118
K45 Other abdominal hernia
0.001 0.890 0.109
E83 Disorders of mineral metabolism
0.002 0.894 0.104
N50.0 Atrophy of testis
0.000 0.907 0.093
K42.1 Umbilical hernia with gangrene
0.000 0.913 0.087
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.916 0.084
E04 Other non-toxic goitre
0.083 0.916 0.000
E83.3 Disorders of phosphorus metabolism
0.001 0.918 0.081
K45.1 Other specified abdominal hernia with gangrene
0.001 0.921 0.078
N48 Other disorders of penis
0.000 0.922 0.078
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.922 0.078
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.924 0.075
E83.8 Other disorders of mineral metabolism
0.001 0.924 0.075
E83.2 Disorders of zinc metabolism
0.001 0.924 0.075
E83.0 Disorders of copper metabolism
0.001 0.924 0.075
K43 Ventral hernia
0.000 0.931 0.069
I83 Varicose veins of lower extremities
0.000 0.932 0.068
N48.4 Impotence of organic origin
0.000 0.939 0.061
E04.8 Other specified non-toxic goitre
0.060 0.940 0.000
N48.2 Other inflammatory disorders of penis
0.000 0.941 0.059
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.944 0.055
K90-K93 Other diseases of the digestive system
0.050 0.945 0.005
N48.5 Ulcer of penis
0.000 0.947 0.052
N48.1 Balanoposthitis
0.000 0.947 0.052
E66 Obesity
0.051 0.949 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.950 0.050
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.950 0.050
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.950 0.050
K43.4 Parastomal hernia with gangrene
0.000 0.950 0.050
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.950 0.050
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.950 0.050
K43.1 Ventral hernia with gangrene
0.000 0.950 0.050
N48.0 Leukoplakia of penis
0.000 0.951 0.049
E04.0 Non-toxic diffuse goitre
0.047 0.953 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.957 0.043
N43.3 Hydrocele, unspecified
0.000 0.958 0.042
E11.4 With neurological complications
0.040 0.958 0.001
K93 Disorders of other digestive organs in diseases classified elsewhere
0.036 0.960 0.004
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.960 0.040
E04.9 Non-toxic goitre, unspecified
0.039 0.961 0.000
N48.3 Priapism
0.000 0.961 0.038
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.961 0.037
E66.1 Drug-induced obesity
0.036 0.963 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.034 0.966 0.000
N48.9 Disorder of penis, unspecified
0.000 0.967 0.033
E83.4 Disorders of magnesium metabolism
0.001 0.968 0.031
E66.0 Obesity due to excess calories
0.030 0.970 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.026 0.971 0.003
K93.1 Megacolon in Chagas' disease
0.026 0.971 0.003
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.026 0.971 0.003
N84.1 Polyp of cervix uteri
0.000 0.972 0.028
K92.0 Haematemesis
0.000 0.973 0.027
K92 Other diseases of digestive system
0.002 0.976 0.023
N48.8 Other specified disorders of penis
0.000 0.976 0.024
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.977 0.023
K92.9 Disease of digestive system, unspecified
0.000 0.978 0.022
N50.1 Vascular disorders of male genital organs
0.000 0.978 0.021
R47.0 Dysphasia and aphasia
0.021 0.979 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.980 0.020
E11.9 Without complications
0.020 0.980 0.000
N48.6 Balanitis xerotica obliterans
0.000 0.982 0.018
K31.7 Polyp of stomach and duodenum
0.000 0.983 0.017
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.984 0.016
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.985 0.015
E66.8 Other obesity
0.015 0.985 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.986 0.014
G25 Other extrapyramidal and movement disorders
0.000 0.987 0.013
K92.8 Other specified diseases of digestive system
0.002 0.987 0.011
K62.0 Anal polyp
0.012 0.988 0.000
G25.3 Myoclonus
0.000 0.988 0.012
E04.1 Non-toxic single thyroid nodule
0.011 0.988 0.001
K31.4 Gastric diverticulum
0.000 0.989 0.011
C80.9 Malignant neoplasm, unspecified
0.000 0.989 0.011
K31 Other diseases of stomach and duodenum
0.000 0.989 0.011
R27.0 Ataxia, unspecified
0.000 0.989 0.011
G25.2 Other specified forms of tremor
0.000 0.989 0.011
K75.4 Autoimmune hepatitis
0.011 0.989 0.000
G25.0 Essential tremor
0.000 0.990 0.010
R47 Speech disturbances, not elsewhere classified
0.010 0.990 0.000
N60.0 Solitary cyst of breast
0.000 0.990 0.010
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.990 0.010
E04.2 Non-toxic multinodular goitre
0.010 0.990 0.000
G24.9 Dystonia, unspecified
0.000 0.990 0.010
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.990 0.010
S20.2 Contusion of thorax
0.010 0.990 0.000
G24 Dystonia
0.000 0.990 0.010
S20 Superficial injury of thorax
0.010 0.990 0.000
R47.1 Dysarthria and anarthria
0.010 0.990 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.990 0.010
G25.5 Other chorea
0.000 0.990 0.010
G25.4 Drug-induced chorea
0.000 0.990 0.010
G25.1 Drug-induced tremor
0.000 0.990 0.010
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.990 0.010
L29.0 Pruritus ani
0.000 0.991 0.009
C80 Malignant neoplasm without specification of site
0.000 0.991 0.009
S20.8 Superficial injuries of other and unspecified parts of thorax
0.009 0.991 0.000
E83.5 Disorders of calcium metabolism
0.001 0.991 0.008
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.991 0.009
S20.3 Other superficial injuries of front wall of thorax
0.009 0.991 0.000
G24.5 Blepharospasm
0.000 0.991 0.009
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.991 0.008
G20-G26 Extrapyramidal and movement disorders
0.000 0.992 0.008
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.992 0.008
K31.0 Acute dilatation of stomach
0.000 0.992 0.008
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.992 0.008
K31.6 Fistula of stomach and duodenum
0.000 0.992 0.008
G24.8 Other dystonia
0.000 0.992 0.008
R27.8 Other and unspecified lack of coordination
0.000 0.992 0.008
R27 Other lack of coordination
0.000 0.992 0.008
K31.3 Pylorospasm, not elsewhere classified
0.000 0.992 0.008
E70-E90 Metabolic disorders
0.006 0.992 0.002
K75.8 Other specified inflammatory liver diseases
0.008 0.992 0.000
S20-S29 Injuries to the thorax
0.008 0.992 0.000
S21 Open wound of thorax
0.008 0.992 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.006 0.992 0.001
K31.5 Obstruction of duodenum
0.000 0.993 0.007
K75 Other inflammatory liver diseases
0.007 0.993 0.000
G24.4 Idiopathic orofacial dystonia
0.000 0.993 0.007
G24.3 Spasmodic torticollis
0.000 0.993 0.007
G24.2 Idiopathic nonfamilial dystonia
0.000 0.993 0.007
G24.1 Idiopathic familial dystonia
0.000 0.993 0.007
G24.0 Drug-induced dystonia
0.000 0.993 0.007
S20.7 Multiple superficial injuries of thorax
0.007 0.993 0.000
S20.0 Contusion of breast
0.007 0.993 0.000
S20.4 Other superficial injuries of back wall of thorax
0.007 0.993 0.000
S20.1 Other and unspecified superficial injuries of breast
0.007 0.993 0.000
S21.9 Open wound of thorax, part unspecified
0.007 0.993 0.000
S21.1 Open wound of front wall of thorax
0.007 0.993 0.000
G21 Secondary Parkinsonism
0.000 0.994 0.006
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.994 0.006
G22 Parkinsonism in diseases classified elsewhere
0.000 0.994 0.006
S21.2 Open wound of back wall of thorax
0.006 0.994 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.006 0.994 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.005 0.994 0.001
S27 Injury of other and unspecified intrathoracic organs
0.006 0.994 0.000
S24 Injury of nerves and spinal cord at thorax level
0.006 0.994 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.005 0.994 0.001
E84 Cystic fibrosis
0.004 0.994 0.001
E77 Disorders of glycoprotein metabolism
0.004 0.994 0.002
E76 Disorders of glycosaminoglycan metabolism
0.004 0.994 0.002
E72 Other disorders of amino-acid metabolism
0.004 0.994 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.004 0.994 0.002
E70 Disorders of aromatic amino-acid metabolism
0.004 0.994 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.004 0.994 0.002
G23 Other degenerative diseases of basal ganglia
0.000 0.994 0.006
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.994 0.006
E85 Amyloidosis
0.004 0.994 0.002
S21.8 Open wound of other parts of thorax
0.006 0.994 0.000
S21.7 Multiple open wounds of thoracic wall
0.006 0.994 0.000
S21.0 Open wound of breast
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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