TreeWAS – Variant ID: rs7781370

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.9 Osteoporosis, unspecified	0.000	0.632	0.368
M81 Osteoporosis without pathological fracture	0.000	0.637	0.363
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.639	0.361
M80-M85 Disorders of bone density and structure	0.000	0.648	0.352
M85 Other disorders of bone density and structure	0.000	0.656	0.344
M80 Osteoporosis with pathological fracture	0.000	0.661	0.339
M85.8 Other specified disorders of bone density and structure	0.000	0.665	0.335
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.669	0.331
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.675	0.325
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.684	0.316
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.685	0.315
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.693	0.307
M81.2 Osteoporosis of disuse	0.000	0.695	0.305
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.702	0.298
M81.4 Drug-induced osteoporosis	0.000	0.706	0.294
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.709	0.291
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.711	0.289
M85.6 Other cyst of bone	0.000	0.712	0.288
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.713	0.287
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.722	0.278
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.724	0.276
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.728	0.272
M85.2 Hyperostosis of skull	0.000	0.732	0.268
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.736	0.264
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.737	0.263
M81.1 Postoophorectomy osteoporosis	0.000	0.739	0.261
M80.8 Other osteoporosis with pathological fracture	0.000	0.740	0.260
M81.6 Localised osteoporosis [Lequesne]	0.000	0.740	0.260
M81.5 Idiopathic osteoporosis	0.000	0.740	0.260
M81.98 Osteoporosis, unspecified (Other)	0.000	0.740	0.260
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.743	0.257
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.745	0.255
M85.5 Aneurysmal bone cyst	0.000	0.753	0.246
M85.3 Osteitis condensans	0.000	0.753	0.246
M85.1 Skeletal fluorosis	0.000	0.753	0.246
M85.68 Other cyst of bone (Other)	0.000	0.755	0.245
M85.0 Fibrous dysplasia (monostotic)	0.000	0.756	0.244
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.757	0.243
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.757	0.243
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.757	0.243
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.759	0.241
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.759	0.241
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.759	0.241
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.761	0.239
M85.64 Other cyst of bone (Hand)	0.000	0.761	0.239
M81.0 Postmenopausal osteoporosis	0.000	0.762	0.238
M82 Osteoporosis in diseases classified elsewhere	0.000	0.764	0.236
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.765	0.235
M84 Disorders of continuity of bone	0.000	0.765	0.235
M83 Adult osteomalacia	0.000	0.766	0.234
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.767	0.233
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.767	0.233
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.767	0.233
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.767	0.233
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.767	0.233
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.767	0.233
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.767	0.233
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.767	0.233
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.767	0.233
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.767	0.233
M85.9 Disorder of bone density and structure, unspecified	0.000	0.769	0.231
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.771	0.229
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.773	0.227
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.775	0.225
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.777	0.223
M81.8 Other osteoporosis	0.000	0.777	0.223
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.780	0.220
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.781	0.218
M81.28 Osteoporosis of disuse (Other)	0.000	0.781	0.218
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.781	0.218
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.781	0.218
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.781	0.218
M81.24 Osteoporosis of disuse (Hand)	0.000	0.781	0.218
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.781	0.218
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.781	0.218
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.781	0.218
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.782	0.218
M85.66 Other cyst of bone (Lower leg)	0.000	0.784	0.216
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.785	0.215
M81.48 Drug-induced osteoporosis (Other)	0.000	0.789	0.211
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.789	0.211
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.789	0.211
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.789	0.211
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.789	0.211
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.789	0.211
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.789	0.211
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.789	0.211
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.791	0.208
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.791	0.208
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.791	0.208
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.791	0.208
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.791	0.208
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.791	0.208
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.791	0.208
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.791	0.208
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.791	0.208
M85.20 Hyperostosis of skull-Mult sites	0.000	0.792	0.208
M85.69 Other cyst of bone (Site unspecified)	0.000	0.793	0.206
M85.63 Other cyst of bone (Forearm)	0.000	0.793	0.206
M85.62 Other cyst of bone (Upper arm)	0.000	0.793	0.206
M85.61 Other cyst of bone (Shoulder region)	0.000	0.793	0.206
M85.60 Other cyst of bone (Multiple sites)	0.000	0.793	0.206
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.794	0.206
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.794	0.206
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.794	0.206
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.794	0.206
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.794	0.206
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.794	0.206
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.794	0.206
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.794	0.206
M85.4 Solitary bone cyst	0.000	0.794	0.205
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.799	0.201
M85.22 Hyperostosis of skull-Upper arm	0.000	0.799	0.200
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.806	0.194
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.807	0.193
M85.29 Hyperostosis of skull-Site unspec	0.000	0.807	0.192
M85.28 Hyperostosis of skull-Other	0.000	0.807	0.192
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.807	0.192
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.807	0.192
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.807	0.192
M85.24 Hyperostosis of skull-Hand	0.000	0.807	0.192
M85.23 Hyperostosis of skull-Forearm	0.000	0.807	0.192
M85.21 Hyperostosis of skull-Shldr region	0.000	0.807	0.192
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.809	0.190
M84.8 Other disorders of continuity of bone	0.000	0.811	0.189
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.812	0.187
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.813	0.187
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.813	0.187
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.813	0.187
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.813	0.187
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.813	0.187
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.813	0.187
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.813	0.187
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.813	0.187
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.813	0.187
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.813	0.187
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.813	0.187
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.813	0.187
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.813	0.187
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.813	0.187
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.813	0.187
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.813	0.187
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.813	0.187
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.813	0.187
M81.58 Idiopathic osteoporosis (Other)	0.000	0.813	0.187
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.813	0.187
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.813	0.187
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.813	0.187
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.813	0.187
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.813	0.187
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.813	0.187
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.813	0.187
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.813	0.187
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.813	0.187
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.813	0.187
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.813	0.187
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.813	0.187
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.813	0.187
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.813	0.187
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.813	0.187
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.813	0.187
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.813	0.187
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.813	0.187
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.814	0.186
M83.8 Other adult osteomalacia	0.000	0.819	0.181
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.821	0.179
M84.3 Stress fracture, not elsewhere classified	0.000	0.821	0.178
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.823	0.177
M85.18 Skeletal fluorosis (Other)	0.000	0.823	0.177
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.823	0.177
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.823	0.177
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.823	0.177
M85.14 Skeletal fluorosis (Hand)	0.000	0.823	0.177
M85.13 Skeletal fluorosis (Forearm)	0.000	0.823	0.177
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.823	0.177
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.823	0.177
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.823	0.177
M85.39 Osteitis condensans (Site unspecified)	0.000	0.823	0.177
M85.38 Osteitis condensans (Other)	0.000	0.823	0.177
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.823	0.177
M85.36 Osteitis condensans (Lower leg)	0.000	0.823	0.177
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.823	0.177
M85.34 Osteitis condensans (Hand)	0.000	0.823	0.177
M85.33 Osteitis condensans (Forearm)	0.000	0.823	0.177
M85.32 Osteitis condensans (Upper arm)	0.000	0.823	0.177
M85.31 Osteitis condensans (Shoulder region)	0.000	0.823	0.177
M85.30 Osteitis condensans (Multiple sites)	0.000	0.823	0.177
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.823	0.177
M85.58 Aneurysmal bone cyst (Other)	0.000	0.823	0.177
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.823	0.177
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.823	0.177
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.823	0.177
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.823	0.177
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.823	0.177
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.823	0.177
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.823	0.177
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.823	0.177
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.825	0.175
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.825	0.175
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.825	0.175
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.825	0.175
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.825	0.175
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.825	0.175
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.825	0.175
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.825	0.175
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.825	0.175
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.825	0.175
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.825	0.175
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.825	0.175
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.825	0.175
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.825	0.175
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.825	0.175
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.825	0.175
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.825	0.175
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.825	0.175
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.825	0.175
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.825	0.175
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.825	0.175
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.825	0.175
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.825	0.175
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.825	0.175
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.825	0.175
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.825	0.175
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.825	0.175
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.825	0.175
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.825	0.175
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.825	0.175
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.825	0.175
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.825	0.175
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.825	0.175
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.825	0.175
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.825	0.175
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.825	0.175
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.825	0.175
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.825	0.175
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.825	0.175
M84.0 Malunion of fracture	0.000	0.826	0.174
M84.2 Delayed union of fracture	0.000	0.829	0.171
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.829	0.170
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.829	0.170
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.829	0.170
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.829	0.170
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.829	0.170
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.829	0.170
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.829	0.170
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.829	0.170
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.830	0.169
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.830	0.169
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.830	0.169
M84.9 Disorder of continuity of bone, unspecified	0.000	0.831	0.169
M83.5 Other drug-induced osteomalacia in adults	0.000	0.832	0.168
M83.4 Aluminum bone disease	0.000	0.832	0.168
M83.2 Adult osteomalacia due to malabsorption	0.000	0.832	0.168
M83.0 Puerperal osteomalacia	0.000	0.832	0.168
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.834	0.166
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.834	0.166
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.834	0.166
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.834	0.166
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.834	0.166
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.834	0.166
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.834	0.166
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.834	0.165
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.835	0.165
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.835	0.165
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.835	0.164
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.835	0.164
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.835	0.164
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.835	0.164
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.835	0.164
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.835	0.164
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.839	0.161
M81.88 Other osteoporosis (Other)	0.000	0.840	0.160
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.840	0.160
M81.86 Other osteoporosis (Lower leg)	0.000	0.840	0.160
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.840	0.160
M81.84 Other osteoporosis (Hand)	0.000	0.840	0.160
M81.83 Other osteoporosis (Forearm)	0.000	0.840	0.160
M81.82 Other osteoporosis (Upper arm)	0.000	0.840	0.160
M81.81 Other osteoporosis (Shoulder region)	0.000	0.840	0.160
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.841	0.159
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.841	0.159
M83.1 Senile osteomalacia	0.000	0.842	0.157
M83.9 Adult osteomalacia, unspecified	0.000	0.843	0.157
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.843	0.157
M83.3 Adult osteomalacia due to malnutrition	0.000	0.844	0.155
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.846	0.154
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.846	0.154
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.846	0.154
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.846	0.154
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.846	0.154
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.846	0.154
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.846	0.154
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.846	0.154
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.846	0.154
M82.1 Osteoporosis in endocrine disorders	0.000	0.847	0.153
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.848	0.152
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.851	0.149
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.852	0.147
M85.48 Solitary bone cyst (Other)	0.000	0.852	0.147
M85.44 Solitary bone cyst (Hand)	0.000	0.852	0.147
M85.43 Solitary bone cyst (Forearm)	0.000	0.852	0.147
M85.42 Solitary bone cyst (Upper arm)	0.000	0.852	0.147
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.852	0.147
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.852	0.147
M81.89 Other osteoporosis (Site unspecified)	0.000	0.855	0.144
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.856	0.143
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.856	0.143
M81.80 Other osteoporosis (Multiple sites)	0.000	0.858	0.142
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.858	0.141
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.860	0.140
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.861	0.139
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.862	0.138
M85.46 Solitary bone cyst (Lower leg)	0.000	0.862	0.137
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.864	0.135
M84.88 Other disorders of continuity of bone (Other)	0.000	0.864	0.135
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.864	0.135
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.864	0.135
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.864	0.135
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.864	0.135
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.864	0.135
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.864	0.135
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.865	0.135
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.866	0.133
M84.03 Malunion of fracture (Forearm)	0.000	0.867	0.133
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.870	0.130
M83.88 Other adult osteomalacia (Other)	0.000	0.870	0.130
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.870	0.130
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.870	0.130
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.870	0.130
M83.84 Other adult osteomalacia (Hand)	0.000	0.870	0.130
M83.83 Other adult osteomalacia (Forearm)	0.000	0.870	0.130
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.870	0.130
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.870	0.130
M84.26 Delayed union of fracture (Lower leg)	0.000	0.870	0.130
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.871	0.129
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.872	0.128
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.872	0.128
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.872	0.128
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.872	0.128
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.872	0.128
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.872	0.128
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.872	0.128
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.872	0.128
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.872	0.128
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.873	0.126
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.875	0.125
M84.09 Malunion of fracture (Site unspecified)	0.000	0.875	0.125
M84.00 Malunion of fracture (Multiple sites)	0.000	0.875	0.125
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.875	0.125
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.876	0.124
M84.4 Pathological fracture, not elsewhere classified	0.000	0.877	0.123
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.877	0.123
M84.28 Delayed union of fracture (Other)	0.000	0.877	0.123
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.877	0.123
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.877	0.123
M84.24 Delayed union of fracture (Hand)	0.000	0.877	0.123
M84.23 Delayed union of fracture (Forearm)	0.000	0.877	0.123
M84.22 Delayed union of fracture (Upper arm)	0.000	0.877	0.123
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.877	0.123
M84.08 Malunion of fracture (Other)	0.000	0.877	0.123
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.000	0.878	0.122
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.000	0.878	0.122
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.000	0.878	0.122
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.000	0.878	0.122
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.000	0.878	0.122
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.000	0.878	0.122
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.000	0.878	0.122
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.000	0.878	0.122
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.000	0.878	0.122
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.000	0.878	0.122
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.000	0.878	0.122
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.000	0.878	0.122
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.000	0.878	0.122
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.000	0.878	0.122
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.000	0.878	0.122
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.000	0.878	0.122
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.000	0.878	0.122
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.000	0.878	0.122
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.000	0.878	0.122
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.000	0.878	0.122
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.879	0.121
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.879	0.121
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.879	0.121
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.879	0.121
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.879	0.121
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.879	0.121
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.879	0.121
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.879	0.121
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.879	0.121
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.879	0.121
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.879	0.120
M83.08 Puerperal osteomalacia (Other)	0.000	0.879	0.120
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.879	0.120
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.879	0.120
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.879	0.120
M83.04 Puerperal osteomalacia (Hand)	0.000	0.879	0.120
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.879	0.120
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.879	0.120
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.879	0.120
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.879	0.120
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.879	0.120
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.879	0.120
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.879	0.120
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.879	0.120
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.879	0.120
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.879	0.120
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.879	0.120
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.879	0.120
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.879	0.120
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.879	0.120
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.879	0.120
M83.48 Aluminium bone disease (Other)	0.000	0.879	0.120
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.879	0.120
M83.46 Aluminium bone disease (Lower leg)	0.000	0.879	0.120
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.879	0.120
M83.44 Aluminium bone disease (Hand)	0.000	0.879	0.120
M83.43 Aluminium bone disease (Forearm)	0.000	0.879	0.120
M83.42 Aluminium bone disease (Upper arm)	0.000	0.879	0.120
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.879	0.120
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.879	0.120
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.879	0.120
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.879	0.120
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.879	0.120
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.879	0.120
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.879	0.120
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.879	0.120
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.879	0.120
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.879	0.120
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.879	0.120
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.879	0.120
M84.06 Malunion of fracture (Lower leg)	0.000	0.881	0.119
M84.04 Malunion of fracture (Hand)	0.000	0.881	0.119
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.881	0.118
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.887	0.113
M83.18 Senile osteomalacia (Other)	0.000	0.887	0.113
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.887	0.113
M83.16 Senile osteomalacia (Lower leg)	0.000	0.887	0.113
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.887	0.113
M83.14 Senile osteomalacia (Hand)	0.000	0.887	0.113
M83.13 Senile osteomalacia (Forearm)	0.000	0.887	0.113
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.887	0.113
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.887	0.113
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.887	0.113
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.887	0.113
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.887	0.113
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.887	0.113
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.887	0.113
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.887	0.113
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.887	0.113
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.887	0.113
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.887	0.113
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.888	0.112
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.888	0.112
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.888	0.112
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.888	0.112
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.888	0.112
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.888	0.112
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.888	0.112
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.888	0.112
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.888	0.112
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.890	0.110
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.890	0.110
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.890	0.110
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.890	0.110
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.890	0.110
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.890	0.110
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.890	0.110
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.890	0.110
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.891	0.109
M84.01 Malunion of fracture (Shoulder region)	0.000	0.891	0.108
M83.12 Senile osteomalacia (Upper arm)	0.000	0.897	0.102
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.898	0.102
M84.02 Malunion of fracture (Upper arm)	0.000	0.900	0.100
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.900	0.100
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.900	0.100
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.900	0.099
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.905	0.094
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.905	0.094
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.910	0.090
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.911	0.089
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.911	0.088
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.911	0.088
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.911	0.088
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.911	0.088
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.911	0.088
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.913	0.086
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.913	0.087
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.915	0.085
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.917	0.083
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.924	0.076
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.934	0.065
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.938	0.062
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.942	0.057
E04.9 Non-toxic goitre, unspecified	0.024	0.976	0.000
E04.1 Non-toxic single thyroid nodule	0.023	0.977	0.000
E04 Other non-toxic goitre	0.020	0.980	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.982	0.018
K72.9 Hepatic failure, unspecified	0.018	0.982	0.000
S32.4 Fracture of acetabulum	0.000	0.983	0.017
S32 Fracture of lumbar spine and pelvis	0.000	0.984	0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations