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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77911647
log Bayes Factor = 25.709
Chromosome 9   position 37,580,543  (GRCh37) Explore rs77911647 on Ensembl!
Variant rs77911647 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Z85 Personal history of malignant neoplasm
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
C44 Other malignant neoplasms of skin
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
Z92 Personal history of medical treatment
0.996 0.004 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
R50-R69 General symptoms and signs
0.991 0.009 0.000
N30-N39 Other diseases of urinary system
0.990 0.010 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.988 0.012 0.000
R55 Syncope and collapse
0.985 0.015 0.000
C44.5 Skin of trunk
0.984 0.016 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.983 0.017 0.000
Z92.3 Personal history of irradiation
0.981 0.019 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.980 0.020 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.971 0.029 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.970 0.030 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.970 0.030 0.000
Z93 Artificial opening status
0.967 0.033 0.000
N10-N16 Renal tubulo-interstitial diseases
0.965 0.035 0.000
S60-S69 Injuries to the wrist and hand
0.964 0.036 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.956 0.044 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.954 0.046 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.953 0.047 0.000
Chapter XX External causes of morbidity and mortality
0.951 0.049 0.000
D50-D53 Nutritional anaemias
0.944 0.056 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.943 0.057 0.000
C43 Malignant melanoma of skin
0.942 0.058 0.000
N13 Obstructive and reflux uropathy
0.941 0.059 0.000
N17-N19 Renal failure
0.941 0.059 0.000
Chapter VI Diseases of the nervous system
0.933 0.067 0.000
C64-C68 Malignant neoplasms of urinary tract
0.931 0.069 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.930 0.070 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
N35 Urethral stricture
0.928 0.072 0.000
Chapter I Certain infectious and parasitic diseases
0.928 0.072 0.000
S80-S89 Injuries to the knee and lower leg
0.927 0.073 0.000
C44.7 Skin of lower limb, including hip
0.926 0.074 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.925 0.075 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.924 0.076 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.924 0.076 0.000
N39 Other disorders of urinary system
0.923 0.077 0.000
D60-D64 Aplastic and other anaemias
0.920 0.080 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.919 0.081 0.000
F30-F39 Mood [affective] disorders
0.918 0.082 0.000
Z51 Other medical care
0.917 0.083 0.000
C79 Secondary malignant neoplasm of other sites
0.917 0.083 0.000
R60 Oedema, not elsewhere classified
0.912 0.088 0.000
C44.2 Skin of ear and external auricular canal
0.908 0.092 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.906 0.094 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.901 0.099 0.000
Chapter VII Diseases of the eye and adnexa
0.900 0.100 0.000
R13 Dysphagia
0.900 0.100 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.898 0.102 0.000
Z51.5 Palliative care
0.897 0.103 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.893 0.107 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.889 0.111 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.888 0.112 0.000
S82 Fracture of lower leg, including ankle
0.888 0.112 0.000
N35.9 Urethral stricture, unspecified
0.884 0.116 0.000
Z94 Transplanted organ and tissue status
0.882 0.118 0.000
Chapter X Diseases of the respiratory system
0.882 0.118 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.880 0.120 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.880 0.120 0.000
D51 Vitamin B12 deficiency anaemia
0.878 0.122 0.000
F10.2 Dependence syndrome
0.877 0.123 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.876 0.124 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.874 0.126 0.000
N18 Chronic renal failure
0.873 0.127 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.872 0.128 0.000
C67 Malignant neoplasm of bladder
0.872 0.128 0.000
H30-H36 Disorders of choroid and retina
0.872 0.128 0.000
G30-G32 Other degenerative diseases of the nervous system
0.871 0.129 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.870 0.130 0.000
Z50 Care involving use of rehabilitation procedures
0.868 0.132 0.000
A30-A49 Other bacterial diseases
0.868 0.132 0.000
S62 Fracture at wrist and hand level
0.867 0.133 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.865 0.135 0.000
F10.0 Acute intoxication
0.864 0.136 0.000
R56 Convulsions, not elsewhere classified
0.863 0.137 0.000
R60.0 Localised oedema
0.861 0.139 0.000
N32 Other disorders of bladder
0.860 0.140 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.858 0.142 0.000
F10.1 Harmful use
0.858 0.142 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.857 0.143 0.000
Z92.0 Personal history of contraception
0.857 0.143 0.000
R47-R49 Symptoms and signs involving speech and voice
0.856 0.144 0.000
S82.8 Fractures of other parts of lower leg
0.855 0.145 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.854 0.146 0.000
D70 Agranulocytosis
0.850 0.150 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.849 0.151 0.000
R54 Senility
0.848 0.152 0.000
Z87 Personal history of other diseases and conditions
0.848 0.152 0.000
T39.0 Salicylates
0.847 0.153 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.843 0.157 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.842 0.158 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.842 0.158 0.000
Chapter VIII Diseases of the ear and mastoid process
0.842 0.158 0.000
Z49 Care involving dialysis
0.840 0.160 0.000
N13.3 Other and unspecified hydronephrosis
0.835 0.165 0.000
E70-E90 Metabolic disorders
0.834 0.166 0.000
N39.4 Other specified urinary incontinence
0.833 0.167 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.833 0.167 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.832 0.168 0.000
Z93.1 Gastrostomy status
0.831 0.169 0.000
C34 Malignant neoplasm of bronchus and lung
0.831 0.169 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.831 0.169 0.000
S90-S99 Injuries to the ankle and foot
0.827 0.173 0.000
Z93.5 Cystostomy status
0.826 0.174 0.000
R50 Fever of unknown origin
0.824 0.176 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.823 0.177 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.820 0.180 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.820 0.180 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.819 0.181 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.818 0.182 0.000
D61 Other aplastic anaemias
0.818 0.182 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.818 0.182 0.000
A41 Other septicaemia
0.817 0.183 0.000
M15-M19 Arthrosis
0.817 0.183 0.000
C83.3 Large cell (diffuse)
0.816 0.184 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.815 0.185 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.813 0.187 0.000
G90-G99 Other disorders of the nervous system
0.812 0.188 0.000
D10-D36 Benign neoplasms
0.812 0.188 0.000
Y40 Systemic antibiotics
0.812 0.188 0.000
Z93.6 Other artificial openings of urinary tract status
0.811 0.189 0.000
Z35 Supervision of high-risk pregnancy
0.811 0.189 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.809 0.190 0.000
F99-F99 Unspecified mental disorder
0.808 0.192 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.807 0.193 0.000
N25-N29 Other disorders of kidney and ureter
0.807 0.193 0.000
C79.2 Secondary malignant neoplasm of skin
0.806 0.194 0.000
H35 Other retinal disorders
0.806 0.194 0.000
R12 Heartburn
0.803 0.197 0.000
M16 Coxarthrosis [arthrosis of hip]
0.802 0.198 0.000
Z98 Other postsurgical states
0.801 0.199 0.000
E10-E14 Diabetes mellitus
0.800 0.200 0.000
N20-N23 Urolithiasis
0.799 0.200 0.000
S62.3 Fracture of other metacarpal bone
0.799 0.201 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.799 0.201 0.000
C44.0 Skin of lip
0.798 0.202 0.000
E20-E35 Disorders of other endocrine glands
0.798 0.202 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.797 0.203 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.797 0.203 0.000
T66-T78 Other and unspecified effects of external causes
0.796 0.204 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.796 0.204 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.795 0.205 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.795 0.205 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.794 0.206 0.000
D50 Iron deficiency anaemia
0.793 0.207 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.792 0.208 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.790 0.210 0.000
D80-D89 Certain disorders involving the immune mechanism
0.788 0.212 0.000
S60 Superficial injury of wrist and hand
0.785 0.215 0.000
F33 Recurrent depressive disorder
0.783 0.217 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.783 0.217 0.000
N60-N64 Disorders of breast
0.782 0.218 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.781 0.219 0.000
B07 Viral warts
0.781 0.219 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.781 0.219 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.780 0.220 0.000
C44.3 Skin of other and unspecified parts of face
0.780 0.220 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.778 0.222 0.000
N18.9 Chronic renal failure, unspecified
0.778 0.222 0.000
R11 Nausea and vomiting
0.777 0.223 0.000
J20-J22 Other acute lower respiratory infections
0.777 0.223 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.776 0.224 0.000
C77.9 Lymph node, unspecified
0.775 0.225 0.000
F32 Depressive episode
0.775 0.225 0.000
Z43 Attention to artificial openings
0.774 0.225 0.000
F10.3 Withdrawal state
0.774 0.226 0.000
N00-N08 Glomerular diseases
0.774 0.226 0.000
D23 Other benign neoplasms of skin
0.772 0.228 0.000
M16.9 Coxarthrosis, unspecified
0.772 0.228 0.000
R56.8 Other and unspecified convulsions
0.771 0.229 0.000
F10.4 Withdrawal state with delirium
0.771 0.229 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.770 0.230 0.000
C92 Myeloid leukaemia
0.770 0.230 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.769 0.231 0.000
Z94.8 Other transplanted organ and tissue status
0.768 0.232 0.000
R63 Symptoms and signs concerning food and fluid intake
0.767 0.233 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.766 0.233 0.000
F60-F69 Disorders of adult personality and behaviour
0.766 0.234 0.000
C34.1 Upper lobe, bronchus or lung
0.765 0.235 0.000
N30 Cystitis
0.764 0.236 0.000
Z51.8 Other specified medical care
0.763 0.237 0.000
H33 Retinal detachments and breaks
0.763 0.237 0.000
D50.9 Iron deficiency anaemia, unspecified
0.760 0.240 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.759 0.241 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.759 0.241 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.758 0.242 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.758 0.242 0.000
N39.0 Urinary tract infection, site not specified
0.757 0.243 0.000
N32.9 Bladder disorder, unspecified
0.757 0.243 0.000
Z45 Adjustment and management of implanted device
0.756 0.244 0.000
Z81 Family history of mental and behavioural disorders
0.756 0.244 0.000
T87 Complications peculiar to reattachment and amputation
0.756 0.244 0.000
Z50.1 Other physical therapy
0.755 0.245 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.755 0.245 0.000
C78.7 Secondary malignant neoplasm of liver
0.754 0.246 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.752 0.248 0.000
H55-H59 Other disorders of eye and adnexa
0.752 0.248 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.751 0.249 0.000
S40-S49 Injuries to the shoulder and upper arm
0.750 0.250 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.750 0.250 0.000
G20-G26 Extrapyramidal and movement disorders
0.750 0.250 0.000
R68 Other general symptoms and signs
0.749 0.250 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.749 0.251 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.748 0.252 0.000
R59 Enlarged lymph nodes
0.748 0.252 0.000
Y40.0 Penicillins
0.747 0.253 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.747 0.253 0.000
E83 Disorders of mineral metabolism
0.746 0.254 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.745 0.255 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.255 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.744 0.256 0.000
D61.9 Aplastic anaemia, unspecified
0.744 0.256 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.743 0.257 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.743 0.257 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.742 0.258 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.742 0.258 0.000
C43.9 Malignant melanoma of skin, unspecified
0.741 0.258 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.742 0.258 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.741 0.259 0.000
N17 Acute renal failure
0.740 0.260 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.739 0.261 0.000
A41.9 Septicaemia, unspecified
0.738 0.262 0.000
C66 Malignant neoplasm of ureter
0.737 0.263 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.736 0.264 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.735 0.265 0.000
D72 Other disorders of white blood cells
0.735 0.265 0.000
Z22 Carrier of infectious disease
0.735 0.265 0.000
D00-D09 In situ neoplasms
0.734 0.266 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.733 0.267 0.000
N39.8 Other specified disorders of urinary system
0.733 0.267 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.732 0.268 0.000
Z85.6 Personal history of leukaemia
0.731 0.269 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.730 0.270 0.000
H60-H62 Diseases of external ear
0.729 0.271 0.000
Z92.8 Personal history of other medical treatment
0.728 0.272 0.000
Z51.1 Chemotherapy session for neoplasm
0.728 0.272 0.000
W00-W19 Falls
0.728 0.272 0.000
C60-C63 Malignant neoplasms of male genital organs
0.727 0.273 0.000
N99-N99 Other disorders of the genitourinary system
0.727 0.273 0.000
Z93.0 Tracheostomy status
0.726 0.274 0.000
T82.3 Mechanical complication of other vascular grafts
0.726 0.274 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.726 0.274 0.000
N18.0 End-stage renal disease
0.725 0.275 0.000
D62 Acute posthaemorrhagic anaemia
0.725 0.275 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.725 0.275 0.000
X60-X84 Intentional self-harm
0.725 0.275 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.724 0.276 0.000
M70-M79 Other soft tissue disorders
0.724 0.276 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.723 0.276 0.000
C44.4 Skin of scalp and neck
0.723 0.277 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.722 0.277 0.000
N18.5 Chronic kidney disease, stage 5
0.722 0.278 0.000
C80 Malignant neoplasm without specification of site
0.721 0.278 0.000
J09-J18 Influenza and pneumonia
0.721 0.279 0.000
N19 Unspecified renal failure
0.720 0.280 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.720 0.280 0.000
J30-J39 Other diseases of upper respiratory tract
0.720 0.280 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.719 0.281 0.000
F31 Bipolar affective disorder
0.718 0.282 0.000
Z50.2 Alcohol rehabilitation
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C67.4 Posterior wall of bladder
0.717 0.283 0.000
Z50.5 Speech therapy
0.717 0.283 0.000
O60-O75 Complications of labour and delivery
0.717 0.283 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.717 0.283 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.717 0.283 0.000
Z93.2 Ileostomy status
0.717 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.716 0.284 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.716 0.284 0.000
C44.8 Overlapping lesion of skin
0.716 0.284 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.716 0.284 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.284 0.000
F80-F89 Disorders of psychological development
0.715 0.284 0.000
F70-F79 Mental retardation
0.715 0.284 0.000
D55-D59 Haemolytic anaemias
0.715 0.285 0.000
R47 Speech disturbances, not elsewhere classified
0.715 0.285 0.000
Z92.9 Personal history of medical treatment, unspecified
0.714 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.714 0.285 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.714 0.286 0.000
C43.5 Malignant melanoma of trunk
0.713 0.287 0.000
S64 Injury of nerves at wrist and hand level
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
N13.4 Hydroureter
0.713 0.287 0.000
D23.3 Skin of other and unspecified parts of face
0.712 0.288 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.711 0.289 0.000
R62 Lack of expected normal physiological development
0.711 0.289 0.000
R57 Shock, not elsewhere classified
0.711 0.289 0.000
R64 Cachexia
0.711 0.289 0.000
R58 Haemorrhage, not elsewhere classified
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.711 0.289 0.000
N37 Urethral disorders in diseases classified elsewhere
0.710 0.290 0.000
N34 Urethritis and urethral syndrome
0.710 0.290 0.000
N33 Bladder disorders in diseases classified elsewhere
0.710 0.290 0.000
Z50.8 Care involving use of rehabilitation procedures
0.710 0.290 0.000
M05-M14 Inflammatory polyarthropathies
0.710 0.290 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.709 0.291 0.000
C67.3 Anterior wall of bladder
0.709 0.291 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.708 0.292 0.000
R42 Dizziness and giddiness
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.706 0.294 0.000
Z10 Routine general health check-up of defined subpopulation
0.705 0.295 0.000
M50-M54 Other dorsopathies
0.704 0.296 0.000
R18 Ascites
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.704 0.296 0.000
Z98.8 Other specified postsurgical states
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.703 0.297 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.703 0.297 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.703 0.297 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.703 0.297 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.703 0.297 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.703 0.297 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.703 0.297 0.000
F11 Mental and behavioural disorders due to use of opioids
0.703 0.297 0.000
M65-M68 Disorders of synovium and tendon
0.703 0.297 0.000
J22 Unspecified acute lower respiratory infection
0.703 0.297 0.000
N32.1 Vesicointestinal fistula
0.702 0.298 0.000
Z49.0 Preparatory care for dialysis
0.702 0.298 0.000
Z49.1 Extracorporeal dialysis
0.701 0.299 0.000
Z54 Convalescence
0.701 0.299 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.701 0.299 0.000
F03 Unspecified dementia
0.700 0.300 0.000
Z45.2 Adjustment and management of vascular access device
0.699 0.301 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.699 0.301 0.000
C67.1 Dome of bladder
0.699 0.301 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.698 0.301 0.000
Z94.0 Kidney transplant status
0.698 0.301 0.000
S92 Fracture of foot, except ankle
0.698 0.302 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
S68 Traumatic amputation of wrist and hand
0.698 0.302 0.000
D24 Benign neoplasm of breast
0.697 0.303 0.000
N30.8 Other cystitis
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.696 0.304 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.696 0.304 0.000
F10.9 Unspecified mental and behavioural disorder
0.695 0.305 0.000
F10.8 Other mental and behavioural disorders
0.695 0.305 0.000
F10.7 Residual and late-onset psychotic disorder
0.695 0.305 0.000
F10.6 Amnesic syndrome
0.695 0.305 0.000
F10.5 Psychotic disorder
0.695 0.305 0.000
Z73 Problems related to life-management difficulty
0.695 0.305 0.000
C67.2 Lateral wall of bladder
0.694 0.306 0.000
Z40 Prophylactic surgery
0.694 0.306 0.000
Z41 Procedures for purposes other than remedying health state
0.694 0.306 0.000
M16.0 Primary coxarthrosis, bilateral
0.694 0.306 0.000
Z93.9 Artificial opening status, unspecified
0.693 0.307 0.000
Z93.8 Other artificial opening status
0.693 0.307 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.693 0.307 0.000
D75 Other diseases of blood and blood-forming organs
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.693 0.307 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.692 0.308 0.000
N15 Other renal tubulo-interstitial diseases
0.692 0.308 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.692 0.308 0.000
N11 Chronic tubulo-interstitial nephritis
0.692 0.308 0.000
Q60-Q64 Congenital malformations of the urinary system
0.692 0.308 0.000
H10-H13 Disorders of conjunctiva
0.691 0.309 0.000
S67 Crushing injury of wrist and hand
0.691 0.309 0.000
S65 Injury of blood vessels at wrist and hand level
0.691 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.691 0.309 0.000
S69 Other and unspecified injuries of wrist and hand
0.691 0.309 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.690 0.310 0.000
Z33 Pregnant state, incidental
0.690 0.310 0.000
T86 Failure and rejection of transplanted organs and tissues
0.688 0.311 0.000
Z13 Special screening examination for other diseases and disorders
0.687 0.313 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.686 0.314 0.000
C77.1 Intrathoracic lymph nodes
0.686 0.314 0.000
Z57 Occupational exposure to risk-factors
0.686 0.314 0.000
S82.0 Fracture of patella
0.686 0.314 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.686 0.314 0.000
C95 Leukaemia of unspecified cell type
0.686 0.314 0.000
C94 Other leukaemias of specified cell type
0.686 0.314 0.000
C93 Monocytic leukaemia
0.686 0.314 0.000
C88 Malignant immunoproliferative diseases
0.686 0.314 0.000
C86 Other specified types of T/NK-cell lymphoma
0.686 0.314 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.686 0.314 0.000
C81 Hodgkin's disease
0.686 0.314 0.000
S82.2 Fracture of shaft of tibia
0.685 0.315 0.000
T79-T79 Certain early complications of trauma
0.685 0.315 0.000
R49 Voice disturbances
0.685 0.315 0.000
Z44 Fitting and adjustment of external prosthetic device
0.684 0.316 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.684 0.316 0.000
N18.4 Chronic kidney disease, stage 4
0.683 0.316 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.683 0.317 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.683 0.317 0.000
A80-A89 Viral infections of the central nervous system
0.682 0.317 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.682 0.318 0.000
Y35-Y36 Legal intervention and operations of war
0.682 0.318 0.000
Y10-Y34 Event of undetermined intent
0.682 0.318 0.000
Y00-Y09 Assault
0.682 0.318 0.000
X85-X99 Assault
0.682 0.318 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.682 0.318 0.000
X50-X57 Overexertion, travel and privation
0.682 0.318 0.000
X30-X39 Exposure to forces of nature
0.682 0.318 0.000
X20-X29 Contact with venomous animals and plants
0.682 0.318 0.000
X10-X19 Contact with heat and hot substances
0.682 0.318 0.000
X00-X09 Exposure to smoke, fire and flames
0.682 0.318 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.682 0.318 0.000
W75-W84 Other accidental threats to breathing
0.682 0.318 0.000
W65-W74 Accidental drowning and submersion
0.682 0.318 0.000
W50-W64 Exposure to animate mechanical forces
0.682 0.318 0.000
V98-V99 Other and unspecified transport accidents
0.682 0.318 0.000
V95-V97 Air and space transport accidents
0.682 0.318 0.000
V90-V94 Water transport accidents
0.682 0.318 0.000
V80-V89 Other land transport accidents
0.682 0.318 0.000
V70-V79 Bus occupant injured in transport accident
0.682 0.318 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.682 0.318 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.682 0.318 0.000
V40-V49 Car occupant injured in transport accident
0.682 0.318 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.682 0.318 0.000
V01-V09 Pedestrian injured in transport accident
0.682 0.318 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.682 0.318 0.000
S82.6 Fracture of lateral malleolus
0.682 0.318 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.681 0.319 0.000
L40-L45 Papulosquamous disorders
0.681 0.319 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.681 0.319 0.000
J95-J99 Other diseases of the respiratory system
0.680 0.320 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.680 0.320 0.000
J00-J06 Acute upper respiratory infections
0.679 0.320 0.000
Z97 Presence of other devices
0.679 0.321 0.000
F00 Dementia in Alzheimer's disease
0.679 0.321 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.679 0.321 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.679 0.321 0.000
C77.3 Axillary and upper limb lymph nodes
0.678 0.322 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.678 0.322 0.000
N39.3 Stress incontinence
0.678 0.322 0.000
D53 Other nutritional anaemias
0.677 0.323 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.677 0.323 0.000
D52 Folate deficiency anaemia
0.676 0.324 0.000
C43.8 Overlapping malignant melanoma of skin
0.675 0.325 0.000
C43.4 Malignant melanoma of scalp and neck
0.675 0.325 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.675 0.325 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.675 0.325 0.000
C43.0 Malignant melanoma of lip
0.675 0.325 0.000
C77.8 Lymph nodes of multiple regions
0.675 0.325 0.000
N13.8 Other obstructive and reflux uropathy
0.675 0.325 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.675 0.325 0.000
N13.6 Pyonephrosis
0.675 0.325 0.000
M86-M90 Other osteopathies
0.675 0.325 0.000
T43.2 Other and unspecified antidepressants
0.674 0.326 0.000
H33.0 Retinal detachment with retinal break
0.673 0.327 0.000
D35.1 Parathyroid gland
0.673 0.327 0.000
Z87.0 Personal history of diseases of the respiratory system
0.672 0.328 0.000
E40-E46 Malnutrition
0.672 0.328 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.671 0.328 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.671 0.329 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.671 0.329 0.000
D23.6 Skin of upper limb, including shoulder
0.671 0.329 0.000
F99 Mental disorder, not otherwise specified
0.671 0.329 0.000
B15-B19 Viral hepatitis
0.671 0.329 0.000
C67.9 Bladder, unspecified
0.671 0.329 0.000
C44.6 Skin of upper limb, including shoulder
0.670 0.330 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.670 0.330 0.000
Z52 Donors of organs and tissues
0.670 0.330 0.000
H36 Retinal disorders in diseases classified elsewhere
0.669 0.331 0.000
Z51.3 Blood transfusion without reported diagnosis
0.669 0.331 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.668 0.332 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.668 0.332 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.668 0.332 0.000
H65-H75 Diseases of middle ear and mastoid
0.668 0.332 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.667 0.333 0.000
C65 Malignant neoplasm of renal pelvis
0.667 0.333 0.000
R50.9 Fever, unspecified
0.667 0.333 0.000
G30 Alzheimer's disease
0.666 0.334 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
M00-M03 Infectious arthropathies
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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