TreeWAS – Variant ID: rs77922938

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K83 Other diseases of biliary tract	0.000	0.609	0.391
K83.8 Other specified diseases of biliary tract	0.000	0.613	0.387
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.614	0.386
K86 Other diseases of pancreas	0.000	0.620	0.380
K83.1 Obstruction of bile duct	0.000	0.636	0.364
K82 Other diseases of gallbladder	0.000	0.638	0.362
K82.8 Other specified diseases of gallbladder	0.000	0.648	0.352
K86.1 Other chronic pancreatitis	0.000	0.658	0.342
K80 Cholelithiasis	0.000	0.662	0.338
K86.9 Disease of pancreas, unspecified	0.000	0.674	0.325
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.683	0.317
K86.2 Cyst of pancreas	0.000	0.689	0.311
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.696	0.304
K83.0 Cholangitis	0.000	0.697	0.302
K86.3 Pseudocyst of pancreas	0.000	0.705	0.295
K85 Acute pancreatitis	0.000	0.705	0.295
K80.4 Calculus of bile duct with cholecystitis	0.000	0.706	0.294
K80.8 Other cholelithiasis	0.000	0.719	0.281
K83.9 Disease of biliary tract, unspecified	0.000	0.719	0.281
K83.5 Biliary cyst	0.000	0.719	0.281
K83.4 Spasm of sphincter of Oddi	0.000	0.719	0.281
K83.3 Fistula of bile duct	0.000	0.719	0.281
K83.2 Perforation of bile duct	0.000	0.719	0.281
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.723	0.277
K86.8 Other specified diseases of pancreas	0.000	0.725	0.275
K82.1 Hydrops of gallbladder	0.000	0.732	0.268
K82.9 Disease of gallbladder, unspecified	0.000	0.740	0.259
K82.3 Fistula of gallbladder	0.000	0.740	0.259
K82.0 Obstruction of gallbladder	0.000	0.740	0.259
K82.2 Perforation of gallbladder	0.000	0.746	0.254
K80.3 Calculus of bile duct with cholangitis	0.000	0.758	0.242
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.766	0.234
K85.1 Biliary acute pancreatitis	0.000	0.769	0.231
K85.8 Other acute pancreatitis	0.000	0.788	0.212
K85.3 Drug-induced acute pancreatitis	0.000	0.788	0.212
K85.2 Alcohol-induced acute pancreatitis	0.000	0.788	0.212
K85.0 Idiopathic acute pancreatitis	0.000	0.788	0.212
K85.9 Acute pancreatitis, unspecified	0.000	0.790	0.210
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.801	0.198
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.801	0.198
K82.4 Cholesterolosis of gallbladder	0.000	0.805	0.195
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.826	0.174
T39.1 4-Aminophenol derivatives	0.000	0.827	0.173
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.827	0.173
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.827	0.173
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.836	0.163
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.846	0.154
T39.0 Salicylates	0.000	0.855	0.145
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.856	0.144
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.856	0.144
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.859	0.141
K81 Cholecystitis	0.000	0.865	0.135
T43.2 Other and unspecified antidepressants	0.000	0.867	0.133
T42.4 Benzodiazepines	0.000	0.867	0.133
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.869	0.131
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.876	0.124
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.876	0.124
T39.4 Antirheumatics, not elsewhere classified	0.000	0.876	0.124
T39.2 Pyrazolone derivatives	0.000	0.876	0.124
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.882	0.118
T40.2 Other opioids	0.000	0.882	0.117
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.889	0.111
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.889	0.111
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.889	0.111
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.889	0.111
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.889	0.111
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.889	0.111
T36 Poisoning by systemic antibiotics	0.000	0.889	0.111
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.890	0.110
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.892	0.108
T43.9 Psychotropic drug, unspecified	0.000	0.897	0.103
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.897	0.103
T43.6 Psychostimulants with abuse potential	0.000	0.897	0.103
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.897	0.103
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.897	0.103
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.898	0.101
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.898	0.101
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.898	0.101
T42.3 Barbiturates	0.000	0.898	0.101
T42.2 Succinimides and oxazolidinediones	0.000	0.898	0.101
T42.1 Iminostilbenes	0.000	0.898	0.101
T42.0 Hydantoin derivatives	0.000	0.898	0.101
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.900	0.100
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.901	0.099
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.903	0.097
K81.8 Other cholecystitis	0.000	0.903	0.097
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.904	0.095
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.905	0.094
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.906	0.094
T40.8 Lysergide [LSD]	0.000	0.906	0.094
T40.7 Cannabis (derivatives)	0.000	0.906	0.094
T40.5 Cocaine	0.000	0.906	0.094
T40.4 Other synthetic narcotics	0.000	0.906	0.094
T40.3 Methadone	0.000	0.906	0.094
T40.1 Heroin	0.000	0.906	0.094
T40.0 Opium	0.000	0.906	0.094
K81.1 Chronic cholecystitis	0.000	0.908	0.092
T40.6 Other and unspecified narcotics	0.000	0.915	0.084
T36.9 Systemic antibiotic, unspecified	0.000	0.920	0.080
T36.8 Other systemic antibiotics	0.000	0.920	0.080
T36.7 Antifungal antibiotics, systemically used	0.000	0.920	0.080
T36.6 Rifamycins	0.000	0.920	0.080
T36.5 Aminoglycosides	0.000	0.920	0.080
T36.4 Tetracyclines	0.000	0.920	0.080
T36.3 Macrolides	0.000	0.920	0.080
T36.2 Chloramphenicol group	0.000	0.920	0.080
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.920	0.080
T36.0 Penicillins	0.000	0.920	0.080
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.920	0.080
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.920	0.080
T37.5 Antiviral drugs	0.000	0.920	0.080
T37.4 Anthelminthics	0.000	0.920	0.080
T37.3 Other antiprotozoal drugs	0.000	0.920	0.080
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.920	0.080
T37.1 Antimycobacterial drugs	0.000	0.920	0.080
T37.0 Sulphonamides	0.000	0.920	0.080
T41.5 Therapeutic gases	0.000	0.920	0.080
T41.4 Anaesthetic, unspecified	0.000	0.920	0.080
T41.3 Local anaesthetics	0.000	0.920	0.080
T41.2 Other and unspecified general anaesthetics	0.000	0.920	0.080
T41.1 Intravenous anaesthetics	0.000	0.920	0.080
T41.0 Inhaled anaesthetics	0.000	0.920	0.080
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.920	0.080
T45.8 Other primarily systemic and haematological agents	0.000	0.920	0.080
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.920	0.080
T45.6 Fibrinolysis-affecting drugs	0.000	0.920	0.080
T45.5 Anticoagulants	0.000	0.920	0.080
T45.4 Iron and its compounds	0.000	0.920	0.080
T45.3 Enzymes, not elsewhere classified	0.000	0.920	0.080
T45.2 Vitamins, not elsewhere classified	0.000	0.920	0.080
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.920	0.080
T45.0 Antiallergic and antiemetic drugs	0.000	0.920	0.080
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.920	0.080
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.920	0.080
T47.7 Emetics	0.000	0.920	0.080
T47.6 Antidiarrhoeal drugs	0.000	0.920	0.080
T47.5 Digestants	0.000	0.920	0.080
T47.4 Other laxatives	0.000	0.920	0.080
T47.3 Saline and osmotic laxatives	0.000	0.920	0.080
T47.2 Stimulant laxatives	0.000	0.920	0.080
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.920	0.080
T47.0 Histamine H(2)-receptor antagonists	0.000	0.920	0.080
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.920	0.080
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.920	0.080
T48.5 Anti-common-cold drugs	0.000	0.920	0.080
T48.4 Expectorants	0.000	0.920	0.080
T48.3 Antitussives	0.000	0.920	0.080
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.920	0.080
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.920	0.080
T48.0 Oxytocic drugs	0.000	0.920	0.080
T49.9 Topical agent, unspecified	0.000	0.920	0.080
T49.8 Other topical agents	0.000	0.920	0.080
T49.7 Dental drugs, topically applied	0.000	0.920	0.080
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.920	0.080
T49.5 Ophthalmological drugs and preparations	0.000	0.920	0.080
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.920	0.080
T49.3 Emollients, demulcents and protectants	0.000	0.920	0.080
T49.2 Local astringents and local detergents	0.000	0.920	0.080
T49.1 Antipruritics	0.000	0.920	0.080
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.920	0.080
T38.9 Other and unspecified hormone antagonists	0.000	0.921	0.079
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.921	0.079
T38.7 Androgens and anabolic congeners	0.000	0.921	0.079
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.921	0.079
T38.5 Other oestrogens and progestogens	0.000	0.921	0.079
T38.4 Oral contraceptives	0.000	0.921	0.079
T38.2 Antithyroid drugs	0.000	0.921	0.079
T38.1 Thyroid hormones and substitutes	0.000	0.921	0.079
T38.0 Glucocorticoids and synthetic analogues	0.000	0.921	0.079
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.921	0.079
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.922	0.077
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.922	0.077
T46.7 Peripheral vasodilators	0.000	0.922	0.077
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.922	0.077
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.922	0.077
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.922	0.077
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.922	0.077
T46.1 Calcium-channel blockers	0.000	0.922	0.077
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.922	0.077
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.926	0.074
K81.0 Acute cholecystitis	0.000	0.929	0.071
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.931	0.069
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.931	0.069
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.931	0.069
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.931	0.069
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.931	0.069
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.931	0.069
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.931	0.069
T44.0 Anticholinesterase agents	0.000	0.931	0.069
T50.8 Diagnostic agents	0.000	0.932	0.068
T50.7 Analeptics and opioid receptor antagonists	0.000	0.932	0.068
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.932	0.068
T50.5 Appetite depressants	0.000	0.932	0.068
T50.4 Drugs affecting uric acid metabolism	0.000	0.932	0.068
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.932	0.068
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.932	0.068
T50.1 Loop [high-ceiling] diuretics	0.000	0.932	0.068
T50.0 Mineralocorticoids and their antagonists	0.000	0.932	0.068
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.936	0.064
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.940	0.059
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.948	0.051
R10.2 Pelvic and perineal pain	0.000	0.949	0.051
R10.4 Other and unspecified abdominal pain	0.000	0.951	0.049
R10 Abdominal and pelvic pain	0.000	0.952	0.048
R10.0 Acute abdomen	0.000	0.956	0.044
K81.9 Cholecystitis, unspecified	0.001	0.961	0.039
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.000	0.964	0.036
R12 Heartburn	0.000	0.968	0.032
R14 Flatulence and related conditions	0.000	0.969	0.031
R17 Unspecified jaundice	0.000	0.969	0.030
R19 Other symptoms and signs involving the digestive system and abdomen	0.000	0.971	0.029
R15 Faecal incontinence	0.000	0.972	0.028
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.973	0.027
R11 Nausea and vomiting	0.000	0.973	0.027
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.975	0.025
Z87.1 Personal history of diseases of the digestive system	0.000	0.975	0.025
R18 Ascites	0.000	0.977	0.023
R19.6 Halitosis	0.000	0.979	0.021
R19.3 Abdominal rigidity	0.000	0.979	0.021
R19.2 Visible peristalsis	0.000	0.979	0.021
R19.1 Abnormal bowel sounds	0.000	0.979	0.021
R19.5 Other fecal abnormalities	0.000	0.981	0.019
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.000	0.981	0.019
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.982	0.018
R16.1 Splenomegaly, not elsewhere classified	0.000	0.982	0.018
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.982	0.018
R19.4 Change in bowel habit	0.000	0.983	0.017
R10.1 Pain localised to upper abdomen	0.000	0.987	0.013
R10.3 Pain localised to other parts of lower abdomen	0.000	0.988	0.012
Z88.6 Personal history of allergy to analgesic agent	0.000	0.989	0.011
R13 Dysphagia	0.000	0.993	0.007
Z71.3 Dietary counselling and surveillance	0.007	0.993	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.994	0.006
Z04.8 Examination and observation for other specified reasons	0.000	0.994	0.006
S09.9 Unspecified injury of head	0.000	0.994	0.006
N18 Chronic renal failure	0.000	0.995	0.005
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.005	0.995	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.995	0.005
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.005	0.995	0.000
Z04.3 Examination and observation following other accident	0.000	0.995	0.005
Z04 Examination and observation for other reasons	0.000	0.995	0.005
Z71.6 Tobacco abuse counselling	0.005	0.995	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.995	0.005
Z71.1 Person with feared complaint in whom no diagnosis is made	0.004	0.995	0.000
N18.0 End-stage renal disease	0.000	0.996	0.004
N18.2 Chronic kidney disease, stage 2	0.000	0.996	0.004
N18.8 Other chronic renal failure	0.000	0.996	0.004
N18.1 Chronic kidney disease, stage 1	0.000	0.996	0.004
Z04.1 Examination and observation following transport accident	0.000	0.996	0.004
Z71.7 Human immunodeficiency virus [HIV] counselling	0.004	0.996	0.000
Z71.5 Drug abuse counselling and surveillance	0.004	0.996	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.004	0.996	0.000
Z71.0 Person consulting on behalf of another person	0.004	0.996	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.996	0.004
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.996	0.004
Z71.8 Other specified counselling	0.004	0.996	0.000
N75.1 Abscess of Bartholin's gland	0.004	0.996	0.000
Z71.2 Person consulting for explanation of investigation findings	0.004	0.996	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.004	0.996	0.000
N75.0 Cyst of Bartholin's gland	0.004	0.996	0.000
Z04.6 General psychiatric examination, requested by authority	0.000	0.996	0.004
Z04.5 Examination and observation following other inflicted injury	0.000	0.996	0.004
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.996	0.004
Z04.2 Examination and observation following work accident	0.000	0.996	0.004
Z04.0 Blood-alcohol and blood-drug test	0.000	0.996	0.004
O03.4 Incomplete, without complication	0.003	0.997	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.997	0.003
Z90.4 Acquired absence of other parts of digestive tract	0.000	0.997	0.003
Z71.9 Counselling, unspecified	0.003	0.997	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
Z50.8 Care involving use of rehabilitation procedures	0.003	0.997	0.000
Z75 Problems related to medical facilities and other health care	0.003	0.997	0.000
S09 Other and unspecified injuries of head	0.000	0.997	0.003
O75.0 Maternal distress during labour and delivery	0.003	0.997	0.000
N19 Unspecified renal failure	0.000	0.997	0.003
I21.2 Acute transmural myocardial infarction of other sites	0.003	0.997	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.997	0.003
N75 Diseases of Bartholin's gland	0.003	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.003	0.997	0.000
Z74 Problems related to care-provider dependency	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.3 Other infection during labour	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.997	0.003
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.997	0.003
Z75.1 Person awaiting admission to adequate facility elsewhere	0.003	0.997	0.000
O75.8 Other specified complications of labour and delivery	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
N17-N19 Renal failure	0.000	0.997	0.003
Z73 Problems related to life-management difficulty	0.003	0.997	0.000
Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
Z75.5 Holiday relief care	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
Z75.2 Other waiting period for investigation and treatment	0.003	0.997	0.000
N41.1 Chronic prostatitis	0.000	0.997	0.003
Z73.9 Problem related to life-management difficulty, unspecified	0.003	0.997	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.997	0.003
Z70 Counselling related to sexual attitude, behaviour and orientation	0.003	0.997	0.000
T51.0 Ethanol	0.000	0.997	0.003
Z74.1 Need for assistance with personal care	0.003	0.997	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.002	0.997	0.000
Z75.8 Other problems related to medical facilities and other health care	0.002	0.997	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.002	0.997	0.000
Z75.0 Medical services not available in home	0.002	0.997	0.000
S09.8 Other specified injuries of head	0.000	0.997	0.002
S09.7 Multiple injuries of head	0.000	0.997	0.002
S09.2 Traumatic rupture of ear drum	0.000	0.997	0.002
S09.1 Injury of muscle and tendon of head	0.000	0.997	0.002
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.997	0.002
Z74.0 Reduced mobility	0.003	0.997	0.000
Z74.8 Other problems related to care-provider dependency	0.002	0.997	0.000
N41.0 Acute prostatitis	0.000	0.997	0.003
Z76.9 Persons encountering health services in unspecified circumstances	0.002	0.997	0.000
H18.4 Corneal degeneration	0.002	0.997	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.002	0.997	0.000
N75.8 Other diseases of Bartholin's gland	0.002	0.997	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.002	0.997	0.000
Z74.3 Need for continuous supervision	0.002	0.997	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.002	0.997	0.000
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
O03 Spontaneous abortion	0.002	0.998	0.000
O60-O75 Complications of labour and delivery	0.002	0.998	0.000
O71 Other obstetric trauma	0.002	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
Z73.5 Social role conflict, not elsewhere classified	0.002	0.998	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.002	0.998	0.000
Z73.2 Lack of relaxation and leisure	0.002	0.998	0.000
Z73.1 Accentuation of personality traits	0.002	0.998	0.000
Z73.0 Burn-out	0.002	0.998	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.002	0.998	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.002	0.998	0.000
Z76.5 Malingerer [conscious situation]	0.002	0.998	0.000
Z76.4 Other boarder in health-care facility	0.002	0.998	0.000
Z76.3 Healthy person accompanying sick person	0.002	0.998	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.002	0.998	0.000
Z76.1 Health supervision and care of foundling	0.002	0.998	0.000
Z76.0 Issue of repeat prescription	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.998	0.002
Z03.8 Observation for other suspected diseases and conditions	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
N41 Inflammatory diseases of prostate	0.000	0.998	0.002
H21.0 Hyphaema	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
O61 Failed induction of labour	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
Z70.9 Sex counselling, unspecified	0.002	0.998	0.000
Z70.8 Other sex counselling	0.002	0.998	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.002	0.998	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.002	0.998	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.002	0.998	0.000
Z70.0 Counselling related to sexual attitude	0.002	0.998	0.000
G12.2 Motor neuron disease	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
O62 Abnormalities of forces of labour	0.002	0.998	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O03.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O03.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O03.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
Z88.5 Personal history of allergy to narcotic agent	0.000	0.998	0.002
O74 Complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.002	0.998	0.000
O60 Preterm delivery	0.002	0.998	0.000
O62.3 Precipitate labour	0.002	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.002	0.998	0.000
O66 Other obstructed labour	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
O71.9 Obstetric trauma, unspecified	0.002	0.998	0.000
O71.7 Obstetric haematoma of pelvis	0.002	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.002	0.998	0.000
O71.5 Other obstetric injury to pelvic organs	0.002	0.998	0.000
O71.3 Obstetric laceration of cervix	0.002	0.998	0.000
O71.2 Postpartum inversion of uterus	0.002	0.998	0.000
O71.1 Rupture of uterus during labour	0.002	0.998	0.000
O71.0 Rupture of uterus before onset of labour	0.002	0.998	0.000
O73 Retained placenta and membranes, without haemorrhage	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.998	0.002
N41.3 Prostatocystitis	0.000	0.998	0.002
N41.2 Abscess of prostate	0.000	0.998	0.002
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.998	0.000
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
O61.8 Other failed induction of labour	0.002	0.998	0.000
O61.1 Failed instrumental induction of labour	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.002	0.998	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
K51 Ulcerative colitis	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
O63.2 Delayed delivery of second twin, triplet, etc.	0.002	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.998	0.002
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
O62.1 Secondary uterine inertia	0.002	0.998	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.002	0.998	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.998	0.002
O67.8 Other intrapartum haemorrhage	0.002	0.998	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
O60.3 Preterm delivery without spontaneous labour	0.001	0.998	0.000
O60.2 Preterm spontaneous labour with term delivery	0.001	0.998	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.001	0.998	0.000
O60.0 Preterm labour without delivery	0.001	0.998	0.000
O62.0 Primary inadequate contractions	0.002	0.998	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.001	0.998	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.001	0.998	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.001	0.998	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.001	0.998	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.001	0.998	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.001	0.998	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.001	0.998	0.000
O65.0 Obstructed labour due to deformed pelvis	0.001	0.998	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.001	0.998	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.001	0.998	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.001	0.998	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.001	0.998	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.001	0.998	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.001	0.998	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.001	0.998	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.001	0.998	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.001	0.998	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.001	0.998	0.000
S62.60 Fracture of other finger (closed)	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.002	0.998	0.000
O66.9 Obstructed labour, unspecified	0.002	0.998	0.000
O66.8 Other specified obstructed labour	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.002	0.998	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.002	0.998	0.000
X59.3 Sports and athletics area	0.002	0.998	0.000
O47 False labour	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
T51.8 Other alcohols	0.000	0.998	0.001
T51.3 Fusel oil	0.000	0.998	0.001
T51.2 2-Propanol	0.000	0.998	0.001
T51.1 Methanol	0.000	0.998	0.001
E83.5 Disorders of calcium metabolism	0.002	0.998	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
O72 Postpartum haemorrhage	0.002	0.998	0.000
F10.2 Dependence syndrome	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.001	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
K51.4 Pseudopolyposis of colon	0.000	0.998	0.002
S01.5 Open wound of lip and oral cavity	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
I21.0 Acute transmural myocardial infarction of anterior wall	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.001	0.998	0.000
H17.1 Other central corneal opacity	0.001	0.998	0.000
H17.0 Adherent leukoma	0.001	0.998	0.000
K51.8 Other ulcerative colitis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations