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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77960360
log Bayes Factor = 18.2632
Chromosome 10   position 17,147,270  (GRCh37) Explore rs77960360 on Ensembl!
Variant rs77960360 is part of Cluster X0268

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
N17-N19 Renal failure
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.998 0.002 0.000
N18 Chronic renal failure
0.996 0.004 0.000
J90-J94 Other diseases of pleura
0.993 0.007 0.000
N18.9 Chronic renal failure, unspecified
0.987 0.013 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.985 0.015 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.982 0.018 0.000
R10.1 Pain localised to upper abdomen
0.979 0.021 0.000
R10 Abdominal and pelvic pain
0.978 0.022 0.000
K29 Gastritis and duodenitis
0.978 0.022 0.000
K80 Cholelithiasis
0.976 0.024 0.000
K29.8 Duodenitis
0.971 0.029 0.000
C78.7 Secondary malignant neoplasm of liver
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.968 0.032 0.000
C15-C26 Malignant neoplasms of digestive organs
0.967 0.033 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.967 0.033 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.966 0.034 0.000
R63 Symptoms and signs concerning food and fluid intake
0.963 0.037 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.963 0.037 0.000
J40-J47 Chronic lower respiratory diseases
0.957 0.043 0.000
C60-C63 Malignant neoplasms of male genital organs
0.956 0.044 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.951 0.049 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.949 0.051 0.000
Chapter I Certain infectious and parasitic diseases
0.945 0.055 0.000
R59 Enlarged lymph nodes
0.943 0.057 0.000
J92 Pleural plaque
0.941 0.059 0.000
N10-N16 Renal tubulo-interstitial diseases
0.937 0.063 0.000
R11 Nausea and vomiting
0.935 0.065 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.930 0.070 0.000
R63.4 Abnormal weight loss
0.928 0.072 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.924 0.076 0.000
C61 Malignant neoplasm of prostate
0.924 0.076 0.000
K20 Oesophagitis
0.923 0.077 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.917 0.083 0.000
K22 Other diseases of oesophagus
0.914 0.086 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.913 0.087 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.913 0.087 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.909 0.091 0.000
C18 Malignant neoplasm of colon
0.908 0.092 0.000
K04 Diseases of pulp and periapical tissues
0.908 0.092 0.000
K55-K64 Other diseases of intestines
0.905 0.095 0.000
K26 Duodenal ulcer
0.904 0.096 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.904 0.096 0.000
K70-K77 Diseases of liver
0.898 0.102 0.000
J90 Pleural effusion, not elsewhere classified
0.896 0.104 0.000
R79 Other abnormal findings of blood chemistry
0.893 0.107 0.000
J43 Emphysema
0.886 0.114 0.000
Chapter VIII Diseases of the ear and mastoid process
0.886 0.114 0.000
R50 Fever of unknown origin
0.885 0.115 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.883 0.117 0.000
R42 Dizziness and giddiness
0.882 0.118 0.000
R51 Headache
0.872 0.128 0.000
C79 Secondary malignant neoplasm of other sites
0.872 0.128 0.000
K50-K52 Noninfective enteritis and colitis
0.868 0.132 0.000
N84 Polyp of female genital tract
0.866 0.134 0.000
N18.5 Chronic kidney disease, stage 5
0.865 0.135 0.000
N72 Inflammatory disease of cervix uteri
0.864 0.136 0.000
J92.9 Pleural plaque without asbestos
0.863 0.137 0.000
C77.0 Lymph nodes of head, face and neck
0.859 0.141 0.000
J44 Other chronic obstructive pulmonary disease
0.858 0.142 0.000
N13 Obstructive and reflux uropathy
0.858 0.142 0.000
M45-M49 Spondylopathies
0.858 0.142 0.000
R59.0 Localised enlarged lymph nodes
0.856 0.144 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.854 0.146 0.000
J95-J99 Other diseases of the respiratory system
0.854 0.146 0.000
N84.1 Polyp of cervix uteri
0.853 0.147 0.000
Chapter XXII Codes for special purposes
0.848 0.152 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.847 0.153 0.000
J09-J18 Influenza and pneumonia
0.846 0.154 0.000
N00-N08 Glomerular diseases
0.844 0.156 0.000
M50-M54 Other dorsopathies
0.844 0.156 0.000
M05-M14 Inflammatory polyarthropathies
0.842 0.158 0.000
R12 Heartburn
0.841 0.159 0.000
R68 Other general symptoms and signs
0.840 0.160 0.000
N19 Unspecified renal failure
0.836 0.164 0.000
J43.9 Emphysema, unspecified
0.835 0.165 0.000
J91 Pleural effusion in conditions classified elsewhere
0.833 0.167 0.000
R59.1 Generalised enlarged lymph nodes
0.831 0.169 0.000
C78.2 Secondary malignant neoplasm of pleura
0.829 0.171 0.000
R52 Pain, not elsewhere classified
0.827 0.173 0.000
R21 Rash and other nonspecific skin eruption
0.826 0.174 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.826 0.174 0.000
K13 Other diseases of lip and oral mucosa
0.825 0.175 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.824 0.175 0.000
N18.0 End-stage renal disease
0.823 0.177 0.000
K51 Ulcerative colitis
0.822 0.178 0.000
C34 Malignant neoplasm of bronchus and lung
0.821 0.178 0.000
K04.8 Radicular cyst
0.819 0.181 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.817 0.183 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.817 0.183 0.000
J93 Pneumothorax
0.816 0.184 0.000
B95-B98 Bacterial, viral and other infectious agents
0.815 0.185 0.000
J92.0 Pleural plaque with presence of asbestos
0.814 0.185 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.814 0.186 0.000
K22.7 Barrett's oesophagus
0.814 0.186 0.000
C78.0 Secondary malignant neoplasm of lung
0.813 0.187 0.000
N86 Erosion and ectropion of cervix uteri
0.813 0.187 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.812 0.188 0.000
M20-M25 Other joint disorders
0.808 0.192 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.808 0.192 0.000
J94 Other pleural conditions
0.808 0.192 0.000
K29.5 Chronic gastritis, unspecified
0.798 0.202 0.000
M51 Other intervertebral disk disorders
0.796 0.204 0.000
R94 Abnormal results of function studies
0.795 0.205 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.793 0.207 0.000
J20-J22 Other acute lower respiratory infections
0.791 0.209 0.000
K76 Other diseases of liver
0.790 0.210 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.790 0.210 0.000
C18.7 Sigmoid colon
0.789 0.211 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.214 0.000
C80 Malignant neoplasm without specification of site
0.784 0.216 0.000
N18.3 Chronic kidney disease, stage 3
0.782 0.218 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.781 0.219 0.000
N95 Menopausal and other perimenopausal disorders
0.779 0.221 0.000
R53 Malaise and fatigue
0.778 0.221 0.000
C64-C68 Malignant neoplasms of urinary tract
0.778 0.222 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.775 0.225 0.000
J60-J70 Lung diseases due to external agents
0.774 0.226 0.000
K90-K93 Other diseases of the digestive system
0.774 0.226 0.000
R50.9 Fever, unspecified
0.771 0.229 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.769 0.231 0.000
C18.5 Splenic flexure
0.769 0.231 0.000
K62 Other diseases of anus and rectum
0.769 0.231 0.000
C20 Malignant neoplasm of rectum
0.768 0.232 0.000
K35-K38 Diseases of appendix
0.768 0.232 0.000
N17 Acute renal failure
0.768 0.232 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.766 0.233 0.000
K25 Gastric ulcer
0.765 0.235 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.764 0.235 0.000
R20 Disturbances of skin sensation
0.764 0.236 0.000
K51.9 Ulcerative colitis, unspecified
0.763 0.237 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.763 0.237 0.000
C18.4 Transverse colon
0.763 0.237 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.762 0.237 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.762 0.238 0.000
K02 Dental caries
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.761 0.239 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.759 0.241 0.000
C34.1 Upper lobe, bronchus or lung
0.757 0.243 0.000
K29.0 Acute haemorrhagic gastritis
0.755 0.245 0.000
M23 Internal derangement of knee
0.753 0.247 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.751 0.248 0.000
H90-H95 Other disorders of ear
0.751 0.249 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.751 0.249 0.000
B99-B99 Other infectious diseases
0.747 0.253 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.747 0.253 0.000
A30-A49 Other bacterial diseases
0.747 0.253 0.000
C25 Malignant neoplasm of pancreas
0.746 0.253 0.000
R41.0 Disorientation, unspecified
0.746 0.254 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.743 0.257 0.000
R40 Somnolence, stupor and coma
0.743 0.257 0.000
K04.6 Periapical abscess with sinus
0.743 0.257 0.000
R23 Other skin changes
0.742 0.258 0.000
N80 Endometriosis
0.742 0.258 0.000
R61 Hyperhidrosis
0.741 0.259 0.000
J40 Bronchitis, not specified as acute or chronic
0.741 0.259 0.000
K56.6 Other and unspecified intestinal obstruction
0.740 0.259 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.740 0.260 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.740 0.260 0.000
M47 Spondylosis
0.740 0.260 0.000
R94.5 Abnormal results of liver function studies
0.739 0.260 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.739 0.261 0.000
N71 Inflammatory disease of uterus, except cervix
0.736 0.264 0.000
C32 Malignant neoplasm of larynx
0.736 0.264 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.736 0.264 0.000
K74 Fibrosis and cirrhosis of liver
0.736 0.264 0.000
B25-B34 Other viral diseases
0.735 0.264 0.000
K26.5 Chronic or unspecified with perforation
0.735 0.265 0.000
J47 Bronchiectasis
0.734 0.266 0.000
K62.0 Anal polyp
0.734 0.266 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.733 0.266 0.000
K12 Stomatitis and related lesions
0.733 0.267 0.000
N10 Acute tubulo-interstitial nephritis
0.733 0.267 0.000
K11 Diseases of salivary glands
0.732 0.268 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.730 0.270 0.000
K29.4 Chronic atrophic gastritis
0.729 0.271 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.729 0.271 0.000
R54 Senility
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
N95.0 Postmenopausal bleeding
0.727 0.273 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.727 0.273 0.000
R68.8 Other specified general symptoms and signs
0.727 0.273 0.000
K75 Other inflammatory liver diseases
0.726 0.274 0.000
J98 Other respiratory disorders
0.725 0.275 0.000
N18.2 Chronic kidney disease, stage 2
0.725 0.275 0.000
M51.2 Other specified intervertebral disk displacement
0.725 0.275 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.725 0.275 0.000
B35-B49 Mycoses
0.724 0.276 0.000
N70 Salpingitis and oophoritis
0.722 0.278 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.721 0.279 0.000
C77.9 Lymph node, unspecified
0.721 0.279 0.000
R10.3 Pain localised to other parts of lower abdomen
0.720 0.280 0.000
K81 Cholecystitis
0.720 0.280 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R57 Shock, not elsewhere classified
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.716 0.284 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.715 0.285 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.715 0.285 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.715 0.285 0.000
K28 Gastrojejunal ulcer
0.715 0.285 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.715 0.285 0.000
N18.8 Other chronic renal failure
0.714 0.286 0.000
N18.4 Chronic kidney disease, stage 4
0.714 0.286 0.000
N18.1 Chronic kidney disease, stage 1
0.714 0.286 0.000
N25-N29 Other disorders of kidney and ureter
0.712 0.287 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.712 0.287 0.000
N13.6 Pyonephrosis
0.711 0.289 0.000
C18.9 Colon, unspecified
0.711 0.289 0.000
K27 Peptic ulcer, site unspecified
0.710 0.290 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
M40-M43 Deforming dorsopathies
0.709 0.290 0.000
R55 Syncope and collapse
0.710 0.290 0.000
H80-H83 Diseases of inner ear
0.709 0.290 0.000
N60-N64 Disorders of breast
0.708 0.291 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.708 0.292 0.000
K57 Diverticular disease of intestine
0.707 0.292 0.000
M86-M90 Other osteopathies
0.707 0.293 0.000
R50.0 Fever with chills
0.707 0.293 0.000
N13.3 Other and unspecified hydronephrosis
0.706 0.294 0.000
K92 Other diseases of digestive system
0.705 0.295 0.000
K26.7 Chronic without haemorrhage or perforation
0.705 0.295 0.000
J18 Pneumonia, organism unspecified
0.704 0.296 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.704 0.296 0.000
M10 Gout
0.704 0.296 0.000
K04.7 Periapical abscess without sinus
0.702 0.298 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.702 0.298 0.000
K29.9 Gastroduodenitis, unspecified
0.701 0.299 0.000
K29.3 Chronic superficial gastritis
0.701 0.299 0.000
K29.2 Alcoholic gastritis
0.701 0.299 0.000
R63.0 Anorexia
0.701 0.299 0.000
K80.3 Calculus of bile duct with cholangitis
0.700 0.300 0.000
K80.8 Other cholelithiasis
0.700 0.300 0.000
K05 Gingivitis and periodontal diseases
0.699 0.300 0.000
C77.5 Intrapelvic lymph nodes
0.699 0.301 0.000
C45 Mesothelioma
0.699 0.301 0.000
M13 Other arthritis
0.697 0.303 0.000
K85 Acute pancreatitis
0.697 0.303 0.000
B15-B19 Viral hepatitis
0.696 0.304 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.696 0.304 0.000
C62 Malignant neoplasm of testis
0.696 0.304 0.000
C22.0 Liver cell carcinoma
0.695 0.305 0.000
R10.0 Acute abdomen
0.695 0.305 0.000
N03 Chronic nephritic syndrome
0.694 0.305 0.000
H65-H75 Diseases of middle ear and mastoid
0.694 0.306 0.000
C22.9 Liver, unspecified
0.694 0.306 0.000
M91-M94 Chondropathies
0.694 0.306 0.000
M60-M63 Disorders of muscles
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.694 0.306 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.693 0.307 0.000
C21 Malignant neoplasm of anus and anal canal
0.693 0.307 0.000
C17 Malignant neoplasm of small intestine
0.693 0.307 0.000
C23 Malignant neoplasm of gallbladder
0.693 0.307 0.000
R46 Symptoms and signs involving appearance and behaviour
0.693 0.307 0.000
R45 Symptoms and signs involving emotional state
0.693 0.307 0.000
R43 Disturbances of smell and taste
0.693 0.307 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.693 0.307 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.691 0.309 0.000
R63.5 Abnormal weight gain
0.691 0.309 0.000
R63.3 Feeding difficulties and mismanagement
0.691 0.309 0.000
R63.2 Polyphagia
0.691 0.309 0.000
R63.1 Polydipsia
0.691 0.309 0.000
R73 Elevated blood glucose level
0.690 0.310 0.000
K10 Other diseases of jaws
0.690 0.310 0.000
K09 Cysts of oral region, not elsewhere classified
0.690 0.310 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.690 0.310 0.000
K03 Other diseases of hard tissues of teeth
0.690 0.310 0.000
K00 Disorders of tooth development and eruption
0.690 0.310 0.000
H90 Conductive and sensorineural hearing loss
0.689 0.311 0.000
K14 Diseases of tongue
0.688 0.312 0.000
K07 Dentofacial anomalies [including malocclusion]
0.688 0.312 0.000
J00-J06 Acute upper respiratory infections
0.688 0.312 0.000
K04.5 Chronic apical periodontitis
0.687 0.313 0.000
J41 Simple and mucopurulent chronic bronchitis
0.686 0.314 0.000
J42 Unspecified chronic bronchitis
0.686 0.314 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.686 0.314 0.000
C60 Malignant neoplasm of penis
0.686 0.314 0.000
R60 Oedema, not elsewhere classified
0.684 0.316 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.683 0.317 0.000
C77.1 Intrathoracic lymph nodes
0.683 0.317 0.000
S90-S99 Injuries to the ankle and foot
0.683 0.317 0.000
C77.4 Inguinal and lower limb lymph nodes
0.682 0.318 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.682 0.318 0.000
R77 Other abnormalities of plasma proteins
0.682 0.318 0.000
R76 Other abnormal immunological findings in serum
0.682 0.318 0.000
R74 Abnormal serum enzyme levels
0.682 0.318 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.682 0.318 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.682 0.318 0.000
R71 Abnormality of red blood cells
0.682 0.318 0.000
K76.8 Other specified diseases of liver
0.681 0.319 0.000
J93.9 Pneumothorax, unspecified
0.680 0.320 0.000
R52.1 Chronic intractable pain
0.678 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.677 0.323 0.000
B65-B83 Helminthiases
0.677 0.323 0.000
B50-B64 Protozoal diseases
0.677 0.323 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.677 0.323 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
A75-A79 Rickettsioses
0.677 0.323 0.000
A70-A74 Other diseases caused by chlamydiae
0.677 0.323 0.000
A65-A69 Other spirochaetal diseases
0.677 0.323 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.677 0.323 0.000
A20-A28 Certain zoonotic bacterial diseases
0.677 0.323 0.000
A15-A19 Tuberculosis
0.677 0.323 0.000
M48 Other spondylopathies
0.677 0.323 0.000
K83 Other diseases of biliary tract
0.677 0.323 0.000
K37 Unspecified appendicitis
0.677 0.323 0.000
N94.6 Dysmenorrhoea, unspecified
0.676 0.324 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.676 0.324 0.000
R18 Ascites
0.676 0.324 0.000
K22.1 Ulcer of oesophagus
0.676 0.324 0.000
L20-L30 Dermatitis and eczema
0.675 0.324 0.000
J94.8 Other specified pleural conditions
0.675 0.325 0.000
K58 Irritable bowel syndrome
0.674 0.325 0.000
K26.3 Acute without haemorrhage or perforation
0.674 0.326 0.000
K22.9 Disease of oesophagus, unspecified
0.674 0.326 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.673 0.327 0.000
R79.0 Abnormal level of blood mineral
0.672 0.328 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.672 0.328 0.000
N15 Other renal tubulo-interstitial diseases
0.672 0.328 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.672 0.328 0.000
N11 Chronic tubulo-interstitial nephritis
0.672 0.328 0.000
R56 Convulsions, not elsewhere classified
0.670 0.330 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.670 0.330 0.000
J46 Status asthmaticus
0.670 0.330 0.000
Chapter V Mental and behavioural disorders
0.670 0.330 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.669 0.331 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.669 0.331 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.669 0.331 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.668 0.332 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.668 0.332 0.000
D00-D09 In situ neoplasms
0.666 0.334 0.000
N20-N23 Urolithiasis
0.665 0.335 0.000
N99-N99 Other disorders of the genitourinary system
0.663 0.336 0.000
K40-K46 Hernia
0.663 0.337 0.000
K22.8 Other specified diseases of oesophagus
0.661 0.339 0.000
N85.1 Endometrial adenomatous hyperplasia
0.661 0.339 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.660 0.340 0.000
K51.2 Ulcerative (chronic) proctitis
0.660 0.340 0.000
T66-T78 Other and unspecified effects of external causes
0.660 0.340 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.660 0.340 0.000
C18.6 Descending colon
0.659 0.341 0.000
N13.4 Hydroureter
0.659 0.341 0.000
C79.2 Secondary malignant neoplasm of skin
0.658 0.342 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.658 0.342 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.658 0.342 0.000
T51 Toxic effect of alcohol
0.658 0.342 0.000
K80.4 Calculus of bile duct with cholecystitis
0.658 0.342 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.658 0.342 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.657 0.342 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.657 0.343 0.000
N76 Other inflammation of vagina and vulva
0.656 0.344 0.000
K22.5 Diverticulum of oesophagus, acquired
0.655 0.345 0.000
K22.3 Perforation of oesophagus
0.655 0.345 0.000
K22.0 Achalasia of cardia
0.655 0.345 0.000
N98 Complications associated with artificial fertilisation
0.655 0.345 0.000
N91 Absent, scanty and rare menstruation
0.655 0.345 0.000
N82 Fistulae involving female genital tract
0.655 0.345 0.000
N96 Habitual aborter
0.655 0.345 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.654 0.345 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.654 0.345 0.000
C31 Malignant neoplasm of accessory sinuses
0.654 0.345 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.654 0.345 0.000
C37 Malignant neoplasm of thymus
0.654 0.345 0.000
C33 Malignant neoplasm of trachea
0.654 0.345 0.000
C16 Malignant neoplasm of stomach
0.654 0.346 0.000
K92.0 Haematemesis
0.654 0.346 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.653 0.347 0.000
T79-T79 Certain early complications of trauma
0.651 0.348 0.000
T33-T35 Frostbite
0.651 0.348 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.651 0.348 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.651 0.348 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.651 0.348 0.000
T00-T07 Injuries involving multiple body regions
0.651 0.348 0.000
S10-S19 Injuries to the neck
0.651 0.348 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.651 0.349 0.000
C18.8 Overlapping lesion of colon
0.651 0.349 0.000
C18.3 Hepatic flexure
0.651 0.349 0.000
C18.1 Appendix
0.651 0.349 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.651 0.349 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.651 0.349 0.000
K04.3 Abnormal hard tissue formation in pulp
0.651 0.349 0.000
K04.2 Pulp degeneration
0.651 0.349 0.000
K04.1 Necrosis of pulp
0.651 0.349 0.000
K04.0 Pulpitis
0.651 0.349 0.000
J98.1 Pulmonary collapse
0.651 0.349 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.650 0.350 0.000
R59.9 Enlarged lymph nodes, unspecified
0.649 0.351 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.649 0.351 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.648 0.351 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.648 0.352 0.000
K26.4 Chronic or unspecified with haemorrhage
0.648 0.352 0.000
K26.2 Acute with both haemorrhage and perforation
0.648 0.352 0.000
K26.1 Acute with perforation
0.648 0.352 0.000
K26.0 Acute with haemorrhage
0.648 0.352 0.000
C77.8 Lymph nodes of multiple regions
0.648 0.352 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.648 0.352 0.000
N94.3 Premenstrual tension syndrome
0.648 0.352 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.647 0.353 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.646 0.354 0.000
L50-L54 Urticaria and erythema
0.645 0.355 0.000
R47-R49 Symptoms and signs involving speech and voice
0.644 0.356 0.000
K77 Liver disorders in diseases classified elsewhere
0.644 0.356 0.000
K73 Chronic hepatitis, not elsewhere classified
0.644 0.356 0.000
K72 Hepatic failure, not elsewhere classified
0.644 0.356 0.000
K71 Toxic liver disease
0.644 0.356 0.000
R94.4 Abnormal results of kidney function studies
0.644 0.356 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.644 0.356 0.000
C15 Malignant neoplasm of oesophagus
0.642 0.358 0.000
R52.9 Pain, unspecified
0.642 0.358 0.000
N80.9 Endometriosis, unspecified
0.642 0.358 0.000
M46 Other inflammatory spondylopathies
0.641 0.359 0.000
J22 Unspecified acute lower respiratory infection
0.641 0.359 0.000
K59 Other functional intestinal disorders
0.639 0.360 0.000
B91 Sequelae of poliomyelitis
0.639 0.361 0.000
T93 Sequelae of injuries of lower limb
0.639 0.361 0.000
K13.0 Diseases of lips
0.638 0.362 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.638 0.362 0.000
S80-S89 Injuries to the knee and lower leg
0.637 0.363 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.637 0.363 0.000
K62.1 Rectal polyp
0.636 0.364 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.636 0.364 0.000
K65-K67 Diseases of peritoneum
0.636 0.364 0.000
J43.8 Other emphysema
0.635 0.365 0.000
J43.2 Centrilobular emphysema
0.635 0.365 0.000
J43.1 Panlobular emphysema
0.635 0.365 0.000
J43.0 MacLeod's syndrome
0.635 0.365 0.000
K01 Embedded and impacted teeth
0.635 0.365 0.000
R50.8 Other specified fever
0.635 0.365 0.000
R50.2 Drug-induced fever
0.635 0.365 0.000
R50.1 Persistent fever
0.635 0.365 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.633 0.367 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.633 0.367 0.000
C22.1 Intrahepatic bile duct carcinoma
0.633 0.367 0.000
M31 Other necrotising vasculopathies
0.632 0.368 0.000
A41 Other septicaemia
0.632 0.368 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.631 0.369 0.000
N85.0 Endometrial glandular hyperplasia
0.631 0.369 0.000
K29.1 Other acute gastritis
0.630 0.370 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.630 0.370 0.000
L60-L75 Disorders of skin appendages
0.628 0.372 0.000
K55 Vascular disorders of intestine
0.626 0.374 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.626 0.374 0.000
K62.7 Radiation proctitis
0.625 0.375 0.000
C79.6 Secondary malignant neoplasm of ovary
0.625 0.375 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.625 0.375 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.625 0.375 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.625 0.375 0.000
U80 Agent resistant to penicillin and related antibiotics
0.623 0.376 0.000
J18.1 Lobar pneumonia, unspecified
0.623 0.377 0.000
K76.9 Liver disease, unspecified
0.623 0.377 0.000
N84.9 Polyp of female genital tract, unspecified
0.621 0.379 0.000
N84.8 Polyp of other parts of female genital tract
0.621 0.379 0.000
N84.3 Polyp of vulva
0.621 0.379 0.000
N84.2 Polyp of vagina
0.621 0.379 0.000
R40.0 Somnolence
0.620 0.380 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.620 0.380 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.619 0.381 0.000
M47.9 Spondylosis, unspecified
0.618 0.382 0.000
K61 Abscess of anal and rectal regions
0.618 0.382 0.000
K02.9 Dental caries, unspecified
0.616 0.384 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.615 0.384 0.000
N13.8 Other obstructive and reflux uropathy
0.615 0.385 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.615 0.385 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.615 0.385 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.615 0.385 0.000
C18.2 Ascending colon
0.615 0.385 0.000
M49 Spondylopathies in diseases classified elsewhere
0.615 0.385 0.000
M45 Ankylosing spondylitis
0.615 0.385 0.000
Q50-Q56 Congenital malformations of genital organs
0.615 0.385 0.000
K44 Diaphragmatic hernia
0.614 0.385 0.000
K82 Other diseases of gallbladder
0.614 0.386 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.612 0.388 0.000
J96 Respiratory failure, not elsewhere classified
0.612 0.388 0.000
M24 Other specific joint derangements
0.612 0.388 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.611 0.389 0.000
R17 Unspecified jaundice
0.610 0.390 0.000
K56.4 Other impaction of intestine
0.610 0.390 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.609 0.390 0.000
C32.0 Glottis
0.609 0.390 0.000
N88 Other noninflammatory disorders of cervix uteri
0.609 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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