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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78018806
log Bayes Factor = 19.3765
Chromosome 13   position 103,238,877  (GRCh37) Explore rs78018806 on Ensembl!
Variant rs78018806 is part of Cluster X0091

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J90 Pleural effusion, not elsewhere classified
1.000 0.000 0.000
J90-J94 Other diseases of pleura
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
J18 Pneumonia, organism unspecified
0.998 0.002 0.000
J18.1 Lobar pneumonia, unspecified
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
M80-M85 Disorders of bone density and structure
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.983 0.017 0.000
C15-C26 Malignant neoplasms of digestive organs
0.977 0.023 0.000
J40-J47 Chronic lower respiratory diseases
0.974 0.026 0.000
D10-D36 Benign neoplasms
0.974 0.026 0.000
N40-N51 Diseases of male genital organs
0.973 0.027 0.000
Chapter XIV Diseases of the genitourinary system
0.971 0.029 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.967 0.033 0.000
I50 Heart failure
0.964 0.036 0.000
D24 Benign neoplasm of breast
0.961 0.039 0.000
S00-S09 Injuries to the head
0.959 0.041 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.959 0.041 0.000
M06 Other rheumatoid arthritis
0.956 0.044 0.000
I50.0 Congestive heart failure
0.955 0.045 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.955 0.045 0.000
M81 Osteoporosis without pathological fracture
0.946 0.054 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.942 0.058 0.000
N43 Hydrocele and spermatocele
0.942 0.058 0.000
F60-F69 Disorders of adult personality and behaviour
0.941 0.059 0.000
M06.9 Rheumatoid arthritis, unspecified
0.933 0.067 0.000
I51 Complications and ill-defined descriptions of heart disease
0.930 0.070 0.000
C15 Malignant neoplasm of oesophagus
0.927 0.073 0.000
Chapter VIII Diseases of the ear and mastoid process
0.926 0.074 0.000
M81.9 Osteoporosis, unspecified
0.921 0.079 0.000
N43.3 Hydrocele, unspecified
0.921 0.079 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.916 0.084 0.000
D11 Benign neoplasm of major salivary glands
0.910 0.090 0.000
L40-L45 Papulosquamous disorders
0.902 0.098 0.000
N48 Other disorders of penis
0.901 0.099 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.901 0.099 0.000
J44 Other chronic obstructive pulmonary disease
0.901 0.099 0.000
J93 Pneumothorax
0.900 0.100 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.900 0.100 0.000
F60 Specific personality disorders
0.899 0.101 0.000
C20 Malignant neoplasm of rectum
0.898 0.102 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.895 0.105 0.000
C71 Malignant neoplasm of brain
0.892 0.108 0.000
J47 Bronchiectasis
0.885 0.115 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.885 0.115 0.000
M07 Psoriatic and enteropathic arthropathies
0.884 0.115 0.000
D22 Melanocytic naevi
0.884 0.116 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.883 0.117 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.883 0.117 0.000
S40-S49 Injuries to the shoulder and upper arm
0.881 0.119 0.000
Chapter XX External causes of morbidity and mortality
0.878 0.122 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.877 0.123 0.000
I45 Other conduction disorders
0.874 0.126 0.000
M85 Other disorders of bone density and structure
0.874 0.126 0.000
C79 Secondary malignant neoplasm of other sites
0.873 0.127 0.000
J95-J99 Other diseases of the respiratory system
0.871 0.129 0.000
I60-I69 Cerebrovascular diseases
0.871 0.129 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.870 0.130 0.000
E70-E90 Metabolic disorders
0.870 0.130 0.000
S32 Fracture of lumbar spine and pelvis
0.868 0.132 0.000
C15.5 Lower third of oesophagus
0.865 0.135 0.000
D11.0 Parotid gland
0.865 0.135 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.863 0.137 0.000
H90-H95 Other disorders of ear
0.862 0.138 0.000
M84 Disorders of continuity of bone
0.862 0.138 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.862 0.138 0.000
M05 Seropositive rheumatoid arthritis
0.860 0.140 0.000
D26 Other benign neoplasms of uterus
0.858 0.142 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.857 0.143 0.000
S06 Intracranial injury
0.852 0.148 0.000
L40 Psoriasis
0.850 0.150 0.000
I46 Cardiac arrest
0.847 0.153 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.844 0.156 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.842 0.158 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.842 0.158 0.000
D22.5 Melanocytic naevi of trunk
0.841 0.159 0.000
N30-N39 Other diseases of urinary system
0.841 0.159 0.000
S70-S79 Injuries to the hip and thigh
0.839 0.161 0.000
F60.9 Personality disorder, unspecified
0.839 0.161 0.000
N10-N16 Renal tubulo-interstitial diseases
0.838 0.162 0.000
S09 Other and unspecified injuries of head
0.835 0.165 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.834 0.166 0.000
I51.7 Cardiomegaly
0.834 0.166 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.832 0.168 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.828 0.172 0.000
H65-H75 Diseases of middle ear and mastoid
0.827 0.173 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.826 0.174 0.000
N41 Inflammatory diseases of prostate
0.826 0.174 0.000
E20-E35 Disorders of other endocrine glands
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.826 0.174 0.000
J18.9 Pneumonia, unspecified
0.825 0.175 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.824 0.176 0.000
N48.6 Balanitis xerotica obliterans
0.823 0.177 0.000
D00-D09 In situ neoplasms
0.821 0.179 0.000
F43 Reaction to severe stress, and adjustment disorders
0.821 0.179 0.000
M86-M90 Other osteopathies
0.819 0.180 0.000
N40 Hyperplasia of prostate
0.817 0.183 0.000
S20-S29 Injuries to the thorax
0.816 0.184 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.816 0.184 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.815 0.185 0.000
L20-L30 Dermatitis and eczema
0.814 0.186 0.000
M07.3 Other psoriatic arthropathies
0.814 0.186 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.812 0.188 0.000
N30 Cystitis
0.807 0.193 0.000
J46 Status asthmaticus
0.806 0.193 0.000
S01 Open wound of head
0.805 0.195 0.000
L89 Decubitus ulcer
0.805 0.195 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.802 0.198 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.799 0.201 0.000
C16 Malignant neoplasm of stomach
0.798 0.201 0.000
L40.9 Psoriasis, unspecified
0.798 0.202 0.000
F80-F89 Disorders of psychological development
0.797 0.203 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.794 0.206 0.000
M85.8 Other specified disorders of bone density and structure
0.793 0.207 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.793 0.207 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.790 0.210 0.000
J14 Pneumonia due to Haemophilus influenzae
0.790 0.210 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.790 0.210 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.790 0.210 0.000
E83 Disorders of mineral metabolism
0.789 0.211 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.787 0.213 0.000
Chapter I Certain infectious and parasitic diseases
0.786 0.214 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.786 0.214 0.000
J11 Influenza, virus not identified
0.784 0.216 0.000
I35 Nonrheumatic aortic valve disorders
0.782 0.218 0.000
H90 Conductive and sensorineural hearing loss
0.781 0.219 0.000
J91 Pleural effusion in conditions classified elsewhere
0.780 0.220 0.000
M65-M68 Disorders of synovium and tendon
0.779 0.221 0.000
N46 Male infertility
0.778 0.222 0.000
F60.3 Emotionally unstable personality disorder
0.776 0.224 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.776 0.224 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.776 0.224 0.000
I26 Pulmonary embolism
0.775 0.225 0.000
F43.0 Acute stress reaction
0.773 0.227 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.772 0.228 0.000
S05 Injury of eye and orbit
0.771 0.229 0.000
J98 Other respiratory disorders
0.767 0.233 0.000
C78.2 Secondary malignant neoplasm of pleura
0.767 0.233 0.000
T66-T78 Other and unspecified effects of external causes
0.766 0.234 0.000
J42 Unspecified chronic bronchitis
0.766 0.234 0.000
N30.9 Cystitis, unspecified
0.765 0.235 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.765 0.235 0.000
F40 Phobic anxiety disorders
0.763 0.237 0.000
C71.9 Brain, unspecified
0.762 0.238 0.000
N50 Other disorders of male genital organs
0.761 0.239 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.761 0.239 0.000
M91-M94 Chondropathies
0.761 0.239 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.760 0.240 0.000
N48.4 Impotence of organic origin
0.759 0.241 0.000
S31 Open wound of abdomen, lower back and pelvis
0.759 0.241 0.000
I05-I09 Chronic rheumatic heart diseases
0.758 0.241 0.000
J93.8 Other pneumothorax
0.758 0.242 0.000
M60-M63 Disorders of muscles
0.757 0.243 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.755 0.245 0.000
S50-S59 Injuries to the elbow and forearm
0.755 0.245 0.000
S10-S19 Injuries to the neck
0.755 0.245 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.754 0.246 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.754 0.246 0.000
C15.9 Oesophagus, unspecified
0.752 0.248 0.000
C71.1 Frontal lobe
0.752 0.248 0.000
D22.4 Melanocytic naevi of scalp and neck
0.751 0.249 0.000
L89.1 Stage II decubitus ulcer
0.750 0.249 0.000
C71.3 Parietal lobe
0.750 0.250 0.000
J00-J06 Acute upper respiratory infections
0.750 0.250 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.749 0.250 0.000
I47 Paroxysmal tachycardia
0.748 0.252 0.000
D16 Benign neoplasm of bone and articular cartilage
0.747 0.253 0.000
S60-S69 Injuries to the wrist and hand
0.746 0.254 0.000
F17.1 Harmful use
0.746 0.254 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.744 0.256 0.000
I36 Nonrheumatic tricuspid valve disorders
0.743 0.257 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.743 0.257 0.000
I51.6 Cardiovascular disease, unspecified
0.742 0.258 0.000
M40-M43 Deforming dorsopathies
0.741 0.259 0.000
I69 Sequelae of cerebrovascular disease
0.741 0.259 0.000
L85 Other epidermal thickening
0.740 0.260 0.000
F99-F99 Unspecified mental disorder
0.737 0.263 0.000
M06.0 Seronegative rheumatoid arthritis
0.737 0.263 0.000
J20-J22 Other acute lower respiratory infections
0.736 0.263 0.000
D26.1 Corpus uteri
0.735 0.265 0.000
S42 Fracture of shoulder and upper arm
0.735 0.265 0.000
I45.9 Conduction disorder, unspecified
0.734 0.266 0.000
I20-I25 Ischaemic heart diseases
0.734 0.266 0.000
I51.8 Other ill-defined heart diseases
0.733 0.267 0.000
M80 Osteoporosis with pathological fracture
0.733 0.267 0.000
N45 Orchitis and epididymitis
0.732 0.267 0.000
T93 Sequelae of injuries of lower limb
0.732 0.268 0.000
M84.0 Malunion of fracture
0.732 0.268 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.730 0.270 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.729 0.271 0.000
J86 Pyothorax
0.729 0.271 0.000
J84 Other interstitial pulmonary diseases
0.729 0.271 0.000
E87.7 Fluid overload
0.728 0.272 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.728 0.272 0.000
J81 Pulmonary oedema
0.728 0.272 0.000
N36 Other disorders of urethra
0.728 0.272 0.000
D27 Benign neoplasm of ovary
0.727 0.273 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.727 0.273 0.000
I65.2 Occlusion and stenosis of carotid artery
0.726 0.274 0.000
I38 Endocarditis, valve unspecified
0.726 0.274 0.000
S32.5 Fracture of pubis
0.725 0.275 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.725 0.275 0.000
C69 Malignant neoplasm of eye and adnexa
0.724 0.276 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.723 0.276 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.723 0.277 0.000
S09.9 Unspecified injury of head
0.723 0.277 0.000
C64-C68 Malignant neoplasms of urinary tract
0.722 0.278 0.000
I46.9 Cardiac arrest, unspecified
0.722 0.278 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.721 0.279 0.000
J93.9 Pneumothorax, unspecified
0.721 0.279 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.719 0.280 0.000
H93 Other disorders of ear, not elsewhere classified
0.719 0.281 0.000
J93.1 Other spontaneous pneumothorax
0.719 0.281 0.000
I30 Acute pericarditis
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.718 0.281 0.000
D10 Benign neoplasm of mouth and pharynx
0.718 0.282 0.000
L81 Other disorders of pigmentation
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
F22 Persistent delusional disorders
0.717 0.283 0.000
J17 Pneumonia in diseases classified elsewhere
0.716 0.284 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.716 0.284 0.000
J12 Viral pneumonia, not elsewhere classified
0.716 0.284 0.000
J09 Influenza due to certain identified influenza virus
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
J18.8 Other pneumonia, organism unspecified
0.715 0.284 0.000
J18.2 Hypostatic pneumonia, unspecified
0.715 0.284 0.000
E83.5 Disorders of calcium metabolism
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
J10 Influenza due to identified influenza virus
0.713 0.286 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.712 0.288 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.712 0.288 0.000
C80 Malignant neoplasm without specification of site
0.711 0.289 0.000
E27 Other disorders of adrenal gland
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
I42 Cardiomyopathy
0.709 0.291 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
M83 Adult osteomalacia
0.708 0.292 0.000
M82 Osteoporosis in diseases classified elsewhere
0.708 0.292 0.000
I51.4 Myocarditis, unspecified
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
Chapter VI Diseases of the nervous system
0.707 0.293 0.000
M81.98 Osteoporosis, unspecified (Other)
0.707 0.293 0.000
I27 Other pulmonary heart diseases
0.705 0.295 0.000
M14 Arthropathies in other diseases classified elsewhere
0.705 0.295 0.000
M12 Other specific arthropathies
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
M08 Juvenile arthritis
0.705 0.295 0.000
L43 Lichen planus
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
S40 Superficial injury of shoulder and upper arm
0.703 0.297 0.000
E88 Other metabolic disorders
0.702 0.298 0.000
J40 Bronchitis, not specified as acute or chronic
0.701 0.298 0.000
J43 Emphysema
0.701 0.299 0.000
C21 Malignant neoplasm of anus and anal canal
0.701 0.299 0.000
C17 Malignant neoplasm of small intestine
0.701 0.299 0.000
C23 Malignant neoplasm of gallbladder
0.701 0.299 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.700 0.300 0.000
D04 Carcinoma in situ of skin
0.700 0.300 0.000
D32 Benign neoplasm of meninges
0.700 0.300 0.000
E86 Volume depletion
0.700 0.300 0.000
I45.5 Other specified heart block
0.699 0.301 0.000
S32.1 Fracture of sacrum
0.699 0.301 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.698 0.301 0.000
J41 Simple and mucopurulent chronic bronchitis
0.698 0.302 0.000
S20 Superficial injury of thorax
0.698 0.302 0.000
D31 Benign neoplasm of eye and adnexa
0.698 0.302 0.000
D30 Benign neoplasm of urinary organs
0.698 0.302 0.000
D29 Benign neoplasm of male genital organs
0.698 0.302 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.698 0.302 0.000
D19 Benign neoplasm of mesothelial tissue
0.698 0.302 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.698 0.302 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.697 0.303 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.697 0.303 0.000
N44 Torsion of testis
0.697 0.303 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.697 0.303 0.000
E87.6 Hypokalaemia
0.697 0.303 0.000
F01 Vascular dementia
0.696 0.304 0.000
F29 Unspecified nonorganic psychosis
0.695 0.304 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.694 0.306 0.000
L29 Pruritus
0.694 0.306 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.694 0.306 0.000
I33 Acute and subacute endocarditis
0.693 0.306 0.000
C15.4 Middle third of oesophagus
0.693 0.307 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.693 0.307 0.000
M89 Other disorders of bone
0.693 0.307 0.000
D26.0 Cervix uteri
0.692 0.308 0.000
F00 Dementia in Alzheimer's disease
0.692 0.308 0.000
W50-W64 Exposure to animate mechanical forces
0.692 0.308 0.000
S01.5 Open wound of lip and oral cavity
0.692 0.308 0.000
D13.2 Duodenum
0.691 0.309 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.689 0.311 0.000
S08 Traumatic amputation of part of head
0.688 0.312 0.000
S07 Crushing injury of head
0.688 0.312 0.000
S04 Injury of cranial nerves
0.688 0.312 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.688 0.312 0.000
L10-L14 Bullous disorders
0.687 0.313 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.687 0.313 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.687 0.313 0.000
J60-J70 Lung diseases due to external agents
0.687 0.313 0.000
N48.8 Other specified disorders of penis
0.686 0.313 0.000
L40.5 Arthropathic psoriasis
0.686 0.314 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.686 0.314 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.686 0.314 0.000
E83.3 Disorders of phosphorus metabolism
0.686 0.314 0.000
M06.8 Other specified rheumatoid arthritis
0.685 0.314 0.000
M06.4 Inflammatory polyarthropathy
0.685 0.314 0.000
M06.3 Rheumatoid nodule
0.685 0.314 0.000
M06.2 Rheumatoid bursitis
0.685 0.314 0.000
M06.1 Adult-onset Still's disease
0.685 0.314 0.000
S01.9 Open wound of head, part unspecified
0.685 0.315 0.000
I05 Rheumatic mitral valve diseases
0.685 0.315 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.684 0.316 0.000
S37 Injury of urinary and pelvic organs
0.684 0.316 0.000
S36 Injury of intra-abdominal organs
0.684 0.316 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.684 0.316 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.684 0.316 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.684 0.316 0.000
T17 Foreign body in respiratory tract
0.684 0.316 0.000
C77.1 Intrathoracic lymph nodes
0.684 0.316 0.000
I51.9 Heart disease, unspecified
0.684 0.316 0.000
T51 Toxic effect of alcohol
0.684 0.316 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.683 0.317 0.000
N30.8 Other cystitis
0.683 0.317 0.000
S80-S89 Injuries to the knee and lower leg
0.683 0.317 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.682 0.317 0.000
I63 Cerebral infarction
0.681 0.319 0.000
D34 Benign neoplasm of thyroid gland
0.681 0.319 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.681 0.319 0.000
S06.5 Traumatic subdural haemorrhage
0.681 0.319 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.680 0.319 0.000
C34 Malignant neoplasm of bronchus and lung
0.680 0.320 0.000
H65 Nonsuppurative otitis media
0.680 0.320 0.000
M81.8 Other osteoporosis
0.678 0.321 0.000
M81.6 Localised osteoporosis [Lequesne]
0.678 0.321 0.000
M81.5 Idiopathic osteoporosis
0.678 0.321 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.678 0.321 0.000
M81.2 Osteoporosis of disuse
0.678 0.321 0.000
M81.1 Postoophorectomy osteoporosis
0.678 0.321 0.000
M81.0 Postmenopausal osteoporosis
0.678 0.321 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.678 0.322 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.678 0.322 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.677 0.322 0.000
I45.1 Other and unspecified right bundle-branch block
0.677 0.323 0.000
E20 Hypoparathyroidism
0.676 0.324 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.676 0.324 0.000
C70 Malignant neoplasm of meninges
0.676 0.324 0.000
N43.4 Spermatocele
0.676 0.324 0.000
N43.2 Other hydrocele
0.676 0.324 0.000
N43.1 Infected hydrocele
0.676 0.324 0.000
N43.0 Encysted hydrocele
0.676 0.324 0.000
E50-E64 Other nutritional deficiencies
0.676 0.324 0.000
J94 Other pleural conditions
0.675 0.325 0.000
S06.2 Diffuse brain injury
0.675 0.325 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.675 0.325 0.000
H90.3 Sensorineural hearing loss, bilateral
0.674 0.325 0.000
F68 Other disorders of adult personality and behaviour
0.674 0.326 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.674 0.326 0.000
F65 Disorders of sexual preference
0.674 0.326 0.000
F64 Gender identity disorders
0.674 0.326 0.000
F63 Habit and impulse disorders
0.674 0.326 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.674 0.326 0.000
F69 Unspecified disorder of adult personality and behaviour
0.674 0.326 0.000
F61 Mixed and other personality disorders
0.674 0.326 0.000
I25 Chronic ischaemic heart disease
0.674 0.326 0.000
J80 Adult respiratory distress syndrome
0.673 0.327 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.672 0.328 0.000
C81 Hodgkin's disease
0.671 0.329 0.000
I45.3 Trifascicular block
0.671 0.329 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.670 0.329 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.670 0.330 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.669 0.331 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.669 0.331 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.669 0.331 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.669 0.331 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.669 0.331 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
S32.3 Fracture of ilium
0.667 0.333 0.000
C71.2 Temporal lobe
0.667 0.333 0.000
I51.5 Myocardial degeneration
0.667 0.333 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.667 0.333 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.667 0.333 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.667 0.333 0.000
I51.0 Cardiac septal defect, acquired
0.667 0.333 0.000
S72 Fracture of femur
0.666 0.334 0.000
S61 Open wound of wrist and hand
0.666 0.334 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.666 0.334 0.000
F10.0 Acute intoxication
0.666 0.334 0.000
T91 Sequelae of injuries of neck and trunk
0.665 0.335 0.000
F40.2 Specific (isolated) phobias
0.665 0.335 0.000
W00-W19 Falls
0.665 0.335 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.665 0.335 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.664 0.335 0.000
C15.8 Overlapping lesion of oesophagus
0.664 0.336 0.000
C15.3 Upper third of oesophagus
0.664 0.336 0.000
C15.2 Abdominal part of oesophagus
0.664 0.336 0.000
C15.1 Thoracic part of oesophagus
0.664 0.336 0.000
C15.0 Cervical part of oesophagus
0.664 0.336 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.664 0.336 0.000
I25.2 Old myocardial infarction
0.664 0.336 0.000
H72 Perforation of tympanic membrane
0.664 0.336 0.000
L90 Atrophic disorders of skin
0.662 0.338 0.000
F25 Schizoaffective disorders
0.661 0.339 0.000
C45 Mesothelioma
0.661 0.339 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.660 0.340 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.660 0.340 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.660 0.340 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.660 0.340 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.660 0.340 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.660 0.340 0.000
S32.4 Fracture of acetabulum
0.660 0.340 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.659 0.341 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.659 0.341 0.000
L85.8 Other specified epidermal thickening
0.659 0.341 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.341 0.000
N11 Chronic tubulo-interstitial nephritis
0.658 0.342 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.657 0.343 0.000
S71 Open wound of hip and thigh
0.657 0.343 0.000
M10 Gout
0.657 0.343 0.000
C26.0 Intestinal tract, part unspecified
0.656 0.344 0.000
E29 Testicular dysfunction
0.655 0.344 0.000
S42.2 Fracture of upper end of humerus
0.655 0.345 0.000
I46.0 Cardiac arrest with successful resuscitation
0.655 0.345 0.000
C77.0 Lymph nodes of head, face and neck
0.655 0.345 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.654 0.346 0.000
D11.9 Major salivary gland, unspecified
0.653 0.347 0.000
D11.7 Other major salivary glands
0.653 0.347 0.000
F23 Acute and transient psychotic disorders
0.652 0.348 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.652 0.348 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.652 0.348 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.651 0.349 0.000
C77.2 Intra-abdominal lymph nodes
0.650 0.350 0.000
D13.1 Stomach
0.649 0.351 0.000
E65-E68 Obesity and other hyperalimentation
0.649 0.351 0.000
S06.3 Focal brain injury
0.648 0.352 0.000
J86.9 Pyothorax without fistula
0.648 0.352 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.648 0.352 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.648 0.352 0.000
Y95 Nosocomial condition
0.648 0.352 0.000
C16.9 Stomach, unspecified
0.647 0.353 0.000
L44 Other papulosquamous disorders
0.647 0.353 0.000
L41 Parapsoriasis
0.647 0.353 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.647 0.353 0.000
L42 Pityriasis rosea
0.647 0.353 0.000
S32.0 Fracture of lumbar vertebra
0.647 0.353 0.000
N48.9 Disorder of penis, unspecified
0.646 0.354 0.000
N48.5 Ulcer of penis
0.646 0.354 0.000
N48.3 Priapism
0.646 0.354 0.000
N48.2 Other inflammatory disorders of penis
0.646 0.354 0.000
N41.0 Acute prostatitis
0.646 0.354 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.646 0.354 0.000
F48 Other neurotic disorders
0.646 0.354 0.000
F44 Dissociative [conversion] disorders
0.646 0.354 0.000
F42 Obsessive-compulsive disorder
0.646 0.354 0.000
J93.0 Spontaneous tension pneumothorax
0.646 0.354 0.000
B99-B99 Other infectious diseases
0.646 0.354 0.000
S09.8 Other specified injuries of head
0.645 0.355 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.645 0.355 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.645 0.355 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.645 0.355 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.645 0.355 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.645 0.355 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.645 0.355 0.000
F11 Mental and behavioural disorders due to use of opioids
0.645 0.355 0.000
F60.8 Other specific personality disorders
0.645 0.355 0.000
F60.7 Dependent personality disorder
0.645 0.355 0.000
F60.6 Anxious [avoidant] personality disorder
0.645 0.355 0.000
F60.5 Anankastic personality disorder
0.645 0.355 0.000
F60.4 Histrionic personality disorder
0.645 0.355 0.000
F60.2 Dissocial personality disorder
0.645 0.355 0.000
F60.1 Schizoid personality disorder
0.645 0.355 0.000
F60.0 Paranoid personality disorder
0.645 0.355 0.000
A30-A49 Other bacterial diseases
0.645 0.355 0.000
N00-N08 Glomerular diseases
0.644 0.356 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.644 0.356 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.644 0.356 0.000
H71 Cholesteatoma of middle ear
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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