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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78060082
log Bayes Factor = 21.2631
Chromosome 10   position 81,065,375  (GRCh37) Explore rs78060082 on Ensembl!
Variant rs78060082 is part of Cluster X0088

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
J45 Asthma
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
J45.9 Asthma, unspecified
0.989 0.011 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.988 0.012 0.000
E65-E68 Obesity and other hyperalimentation
0.983 0.017 0.000
E66 Obesity
0.978 0.022 0.000
M15-M19 Arthrosis
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.974 0.026 0.000
K40-K46 Hernia
0.974 0.026 0.000
K42 Umbilical hernia
0.966 0.034 0.000
J20-J22 Other acute lower respiratory infections
0.963 0.037 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.962 0.038 0.000
E66.9 Obesity, unspecified
0.960 0.040 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.959 0.041 0.000
Chapter XXI Factors influencing health status and contact with health services
0.958 0.042 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.958 0.042 0.000
K70-K77 Diseases of liver
0.956 0.044 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.952 0.048 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.950 0.050 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.943 0.057 0.000
Chapter VII Diseases of the eye and adnexa
0.938 0.062 0.000
Chapter XIV Diseases of the genitourinary system
0.937 0.063 0.000
J09-J18 Influenza and pneumonia
0.937 0.063 0.000
J22 Unspecified acute lower respiratory infection
0.936 0.064 0.000
M17 Gonarthrosis [arthrosis of knee]
0.936 0.064 0.000
G40-G47 Episodic and paroxysmal disorders
0.935 0.065 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.933 0.067 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.928 0.072 0.000
K35-K38 Diseases of appendix
0.925 0.075 0.000
E66.8 Other obesity
0.923 0.077 0.000
G62 Other polyneuropathies
0.922 0.078 0.000
Chapter I Certain infectious and parasitic diseases
0.921 0.079 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
M05-M14 Inflammatory polyarthropathies
0.918 0.082 0.000
I30-I52 Other forms of heart disease
0.918 0.082 0.000
M50-M54 Other dorsopathies
0.917 0.083 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.914 0.086 0.000
M17.9 Gonarthrosis, unspecified
0.912 0.088 0.000
E10-E14 Diabetes mellitus
0.912 0.088 0.000
J43 Emphysema
0.908 0.092 0.000
Z86 Personal history of certain other diseases
0.905 0.095 0.000
Z86.4 Personal history of psychoactive substance abuse
0.905 0.095 0.000
G47 Sleep disorders
0.905 0.095 0.000
I45 Other conduction disorders
0.901 0.099 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.898 0.102 0.000
J18 Pneumonia, organism unspecified
0.891 0.109 0.000
Z85 Personal history of malignant neoplasm
0.888 0.112 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.888 0.112 0.000
Chapter VIII Diseases of the ear and mastoid process
0.887 0.113 0.000
K35 Acute appendicitis
0.887 0.113 0.000
K75 Other inflammatory liver diseases
0.883 0.117 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.878 0.122 0.000
E20-E35 Disorders of other endocrine glands
0.874 0.126 0.000
Z90.7 Acquired absence of genital organ(s)
0.874 0.126 0.000
S00-S09 Injuries to the head
0.873 0.127 0.000
Chapter XX External causes of morbidity and mortality
0.871 0.129 0.000
H43-H45 Disorders of vitreous body and globe
0.869 0.131 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.869 0.131 0.000
T81 Complications of procedures, not elsewhere classified
0.869 0.131 0.000
K65-K67 Diseases of peritoneum
0.868 0.132 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.867 0.133 0.000
M06 Other rheumatoid arthritis
0.866 0.134 0.000
S80-S89 Injuries to the knee and lower leg
0.863 0.137 0.000
K08 Other disorders of teeth and supporting structures
0.858 0.142 0.000
G62.8 Other specified polyneuropathies
0.858 0.142 0.000
I45.1 Other and unspecified right bundle-branch block
0.857 0.143 0.000
G47.3 Sleep apnoea
0.855 0.145 0.000
M18 Arthrosis of first carpometacarpal joint
0.854 0.146 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.853 0.147 0.000
E14 Unspecified diabetes mellitus
0.852 0.148 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.852 0.148 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.851 0.149 0.000
I47 Paroxysmal tachycardia
0.849 0.151 0.000
G90-G99 Other disorders of the nervous system
0.848 0.152 0.000
G82 Paraplegia and tetraplegia
0.846 0.153 0.000
G81 Hemiplegia
0.845 0.155 0.000
J43.9 Emphysema, unspecified
0.842 0.158 0.000
D50-D53 Nutritional anaemias
0.842 0.158 0.000
S20-S29 Injuries to the thorax
0.841 0.159 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.840 0.160 0.000
S50-S59 Injuries to the elbow and forearm
0.839 0.161 0.000
G62.9 Polyneuropathy, unspecified
0.834 0.166 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.833 0.167 0.000
M31 Other necrotising vasculopathies
0.833 0.167 0.000
J60-J70 Lung diseases due to external agents
0.828 0.172 0.000
H43 Disorders of vitreous body
0.828 0.172 0.000
M50 Cervical disk disorders
0.828 0.172 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.821 0.179 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.819 0.181 0.000
M06.9 Rheumatoid arthritis, unspecified
0.818 0.182 0.000
A30-A49 Other bacterial diseases
0.816 0.184 0.000
J18.1 Lobar pneumonia, unspecified
0.812 0.188 0.000
M65-M68 Disorders of synovium and tendon
0.811 0.189 0.000
K41 Femoral hernia
0.809 0.191 0.000
E14.9 Without complications
0.807 0.193 0.000
K90-K93 Other diseases of the digestive system
0.806 0.194 0.000
I70 Atherosclerosis
0.805 0.195 0.000
J18.9 Pneumonia, unspecified
0.804 0.196 0.000
N92 Excessive, frequent and irregular menstruation
0.803 0.197 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.803 0.197 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.802 0.198 0.000
M21 Other acquired deformities of limbs
0.801 0.199 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.800 0.200 0.000
M24 Other specific joint derangements
0.799 0.201 0.000
M40-M43 Deforming dorsopathies
0.798 0.202 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.798 0.202 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.797 0.203 0.000
G47.8 Other sleep disorders
0.796 0.204 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.790 0.210 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.788 0.212 0.000
K76 Other diseases of liver
0.786 0.214 0.000
I47.1 Supraventricular tachycardia
0.786 0.214 0.000
S01 Open wound of head
0.785 0.215 0.000
N60-N64 Disorders of breast
0.785 0.215 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.784 0.216 0.000
K70 Alcoholic liver disease
0.783 0.217 0.000
Z98 Other postsurgical states
0.783 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.782 0.218 0.000
I45.6 Preexcitation syndrome
0.782 0.218 0.000
K75.9 Inflammatory liver disease, unspecified
0.782 0.218 0.000
N10-N16 Renal tubulo-interstitial diseases
0.782 0.218 0.000
K66 Other disorders of peritoneum
0.780 0.220 0.000
K35.9 Acute appendicitis, unspecified
0.778 0.222 0.000
Z86.0 Personal history of other neoplasms
0.778 0.222 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.777 0.223 0.000
S81 Open wound of lower leg
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.777 0.223 0.000
K07 Dentofacial anomalies [including malocclusion]
0.775 0.225 0.000
J45.0 Predominantly allergic asthma
0.773 0.227 0.000
G82.2 Paraplegia, unspecified
0.773 0.227 0.000
K35.8 Acute appendicitis, other and unspecified
0.772 0.228 0.000
H40-H42 Glaucoma
0.771 0.229 0.000
H43.8 Other disorders of vitreous body
0.770 0.230 0.000
G81.9 Hemiplegia, unspecified
0.770 0.230 0.000
I38 Endocarditis, valve unspecified
0.769 0.231 0.000
T86 Failure and rejection of transplanted organs and tissues
0.769 0.231 0.000
N30-N39 Other diseases of urinary system
0.768 0.232 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.767 0.233 0.000
M86-M90 Other osteopathies
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.765 0.235 0.000
M31.6 Other giant cell arteritis
0.765 0.235 0.000
M45-M49 Spondylopathies
0.764 0.236 0.000
I71 Aortic aneurysm and dissection
0.763 0.237 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.763 0.237 0.000
D51 Vitamin B12 deficiency anaemia
0.763 0.237 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.763 0.237 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.761 0.239 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.760 0.240 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.760 0.240 0.000
M17.5 Other secondary gonarthrosis
0.758 0.242 0.000
N86 Erosion and ectropion of cervix uteri
0.758 0.242 0.000
N72 Inflammatory disease of cervix uteri
0.757 0.243 0.000
J42 Unspecified chronic bronchitis
0.755 0.245 0.000
I78 Diseases of capillaries
0.754 0.246 0.000
I60-I69 Cerebrovascular diseases
0.753 0.247 0.000
M80-M85 Disorders of bone density and structure
0.753 0.247 0.000
B95-B98 Bacterial, viral and other infectious agents
0.752 0.248 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
K43 Ventral hernia
0.749 0.251 0.000
M00-M03 Infectious arthropathies
0.749 0.251 0.000
T79-T79 Certain early complications of trauma
0.748 0.252 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.748 0.252 0.000
M50.2 Other cervical disk displacement
0.748 0.252 0.000
K12 Stomatitis and related lesions
0.747 0.253 0.000
H10-H13 Disorders of conjunctiva
0.747 0.253 0.000
Z89 Acquired absence of limb
0.747 0.253 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.747 0.253 0.000
S60-S69 Injuries to the wrist and hand
0.744 0.256 0.000
T66-T78 Other and unspecified effects of external causes
0.744 0.256 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.742 0.258 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.742 0.258 0.000
D50 Iron deficiency anaemia
0.741 0.259 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.739 0.261 0.000
I77 Other disorders of arteries and arterioles
0.738 0.262 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.737 0.263 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.736 0.264 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.736 0.264 0.000
K08.3 Retained dental root
0.735 0.265 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.733 0.267 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.730 0.270 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.730 0.270 0.000
I51 Complications and ill-defined descriptions of heart disease
0.729 0.271 0.000
N88 Other noninflammatory disorders of cervix uteri
0.729 0.271 0.000
I72 Other aneurysm
0.727 0.273 0.000
M19 Other arthrosis
0.727 0.273 0.000
G83 Other paralytic syndromes
0.726 0.274 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.725 0.275 0.000
I33 Acute and subacute endocarditis
0.721 0.279 0.000
I30 Acute pericarditis
0.721 0.279 0.000
I45.2 Bifascicular block
0.719 0.280 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.719 0.281 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.719 0.281 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N00-N08 Glomerular diseases
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
S01.0 Open wound of scalp
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
M51 Other intervertebral disk disorders
0.715 0.285 0.000
N17-N19 Renal failure
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.285 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.714 0.286 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.713 0.287 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.713 0.287 0.000
J45.8 Mixed asthma
0.713 0.287 0.000
J45.1 Nonallergic asthma
0.713 0.287 0.000
K74 Fibrosis and cirrhosis of liver
0.712 0.288 0.000
G44 Other headache syndromes
0.712 0.288 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.712 0.288 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.710 0.290 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.709 0.291 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.291 0.000
J10 Influenza due to identified influenza virus
0.708 0.292 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.707 0.293 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.707 0.293 0.000
Z83 Family history of other specific disorders
0.707 0.293 0.000
Z72 Problems related to lifestyle
0.707 0.293 0.000
E67 Other hyperalimentation
0.705 0.295 0.000
E68 Sequelae of hyperalimentation
0.705 0.295 0.000
E65 Localised adiposity
0.705 0.295 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.704 0.296 0.000
M17.0 Primary gonarthrosis, bilateral
0.704 0.296 0.000
M16 Coxarthrosis [arthrosis of hip]
0.704 0.296 0.000
H43.3 Other vitreous opacities
0.704 0.296 0.000
G40 Epilepsy
0.704 0.296 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.704 0.296 0.000
K75.8 Other specified inflammatory liver diseases
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.702 0.297 0.000
M34 Systemic sclerosis
0.702 0.298 0.000
K75.4 Autoimmune hepatitis
0.702 0.298 0.000
E11 Non-insulin-dependent diabetes mellitus
0.702 0.298 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.702 0.298 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.701 0.299 0.000
E66.1 Drug-induced obesity
0.701 0.299 0.000
E66.0 Obesity due to excess calories
0.701 0.299 0.000
H65 Nonsuppurative otitis media
0.701 0.299 0.000
K92 Other diseases of digestive system
0.701 0.299 0.000
M15 Polyarthrosis
0.700 0.299 0.000
H20 Iridocyclitis
0.701 0.299 0.000
S20 Superficial injury of thorax
0.700 0.300 0.000
K02 Dental caries
0.700 0.300 0.000
J46 Status asthmaticus
0.699 0.301 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.699 0.301 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.699 0.301 0.000
I00-I02 Acute rheumatic fever
0.698 0.301 0.000
K45 Other abdominal hernia
0.698 0.302 0.000
Z98.8 Other specified postsurgical states
0.697 0.303 0.000
Z85.6 Personal history of leukaemia
0.697 0.303 0.000
N60 Benign mammary dysplasia
0.697 0.303 0.000
M67 Other disorders of synovium and tendon
0.697 0.303 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.696 0.303 0.000
H55-H59 Other disorders of eye and adnexa
0.695 0.305 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.695 0.305 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.694 0.305 0.000
S52 Fracture of forearm
0.694 0.306 0.000
Z99.8 Dependence on other enabling machines and devices
0.694 0.306 0.000
E26 Hyperaldosteronism
0.693 0.307 0.000
Z04 Examination and observation for other reasons
0.693 0.307 0.000
K42.1 Umbilical hernia with gangrene
0.692 0.307 0.000
S81.8 Open wound of other parts of lower leg
0.692 0.308 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.692 0.308 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.691 0.309 0.000
M21.3 Wrist or foot drop (acquired)
0.690 0.310 0.000
J21 Acute bronchiolitis
0.690 0.310 0.000
J20 Acute bronchitis
0.690 0.310 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.690 0.310 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.690 0.310 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.690 0.310 0.000
N97 Female infertility
0.689 0.311 0.000
B35-B49 Mycoses
0.689 0.311 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.689 0.311 0.000
H80-H83 Diseases of inner ear
0.688 0.311 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.688 0.312 0.000
K07.6 Temporomandibular joint disorders
0.687 0.313 0.000
I45.9 Conduction disorder, unspecified
0.687 0.313 0.000
K66.0 Peritoneal adhesions
0.686 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.685 0.315 0.000
K73 Chronic hepatitis, not elsewhere classified
0.685 0.315 0.000
K71 Toxic liver disease
0.685 0.315 0.000
M05 Seropositive rheumatoid arthritis
0.685 0.315 0.000
A41 Other septicaemia
0.685 0.315 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.685 0.315 0.000
I73 Other peripheral vascular diseases
0.684 0.316 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.683 0.317 0.000
K10 Other diseases of jaws
0.682 0.318 0.000
G61 Inflammatory polyneuropathy
0.682 0.318 0.000
G60 Hereditary and idiopathic neuropathy
0.682 0.318 0.000
G64 Other disorders of peripheral nervous system
0.682 0.318 0.000
M54 Dorsalgia
0.682 0.318 0.000
M24.1 Other articular cartilage disorders
0.682 0.318 0.000
A49 Bacterial infection of unspecified site
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.682 0.318 0.000
D50.9 Iron deficiency anaemia, unspecified
0.682 0.318 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.681 0.319 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.681 0.319 0.000
G80 Infantile cerebral palsy
0.681 0.319 0.000
N13 Obstructive and reflux uropathy
0.680 0.320 0.000
K46 Unspecified abdominal hernia
0.679 0.321 0.000
I69 Sequelae of cerebrovascular disease
0.678 0.322 0.000
M06.0 Seronegative rheumatoid arthritis
0.677 0.322 0.000
E29 Testicular dysfunction
0.677 0.323 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.677 0.323 0.000
E50-E64 Other nutritional deficiencies
0.676 0.324 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.676 0.324 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.676 0.324 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.676 0.324 0.000
T82.3 Mechanical complication of other vascular grafts
0.676 0.324 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.676 0.324 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.676 0.324 0.000
M53 Other dorsopathies, not elsewhere classified
0.675 0.324 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.674 0.325 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.674 0.326 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.674 0.326 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.674 0.326 0.000
M25 Other joint disorders, not elsewhere classified
0.674 0.326 0.000
G30-G32 Other degenerative diseases of the nervous system
0.673 0.326 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.672 0.327 0.000
K09 Cysts of oral region, not elsewhere classified
0.672 0.328 0.000
J17 Pneumonia in diseases classified elsewhere
0.671 0.328 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.671 0.328 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.671 0.328 0.000
J12 Viral pneumonia, not elsewhere classified
0.671 0.328 0.000
J11 Influenza, virus not identified
0.671 0.328 0.000
J14 Pneumonia due to Haemophilus influenzae
0.671 0.328 0.000
J09 Influenza due to certain identified influenza virus
0.671 0.328 0.000
H30-H36 Disorders of choroid and retina
0.672 0.328 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.671 0.328 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.671 0.329 0.000
M17.3 Other posttraumatic gonarthrosis
0.671 0.329 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.671 0.329 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.670 0.330 0.000
G41 Status epilepticus
0.670 0.330 0.000
I74 Arterial embolism and thrombosis
0.670 0.330 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.669 0.331 0.000
Z12 Special screening examination for neoplasms
0.668 0.332 0.000
W20-W49 Exposure to inanimate mechanical forces
0.668 0.332 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.666 0.333 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.666 0.334 0.000
I34 Nonrheumatic mitral valve disorders
0.666 0.334 0.000
M50.1 Cervical disk disorder with radiculopathy
0.665 0.335 0.000
M22 Disorders of patella
0.665 0.335 0.000
N92.5 Other specified irregular menstruation
0.665 0.335 0.000
M13 Other arthritis
0.665 0.335 0.000
K38 Other diseases of appendix
0.663 0.336 0.000
K36 Other appendicitis
0.663 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
I47.2 Ventricular tachycardia
0.663 0.337 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.662 0.337 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.662 0.338 0.000
V10-V19 Pedal cyclist injured in transport accident
0.662 0.338 0.000
G62.2 Polyneuropathy due to other toxic agents
0.661 0.339 0.000
G62.1 Alcoholic polyneuropathy
0.661 0.339 0.000
G62.0 Drug-induced polyneuropathy
0.661 0.339 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.661 0.339 0.000
I95 Hypotension
0.660 0.340 0.000
B99-B99 Other infectious diseases
0.660 0.340 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.660 0.340 0.000
B65-B83 Helminthiases
0.660 0.340 0.000
B50-B64 Protozoal diseases
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
B15-B19 Viral hepatitis
0.660 0.340 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.660 0.340 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
A75-A79 Rickettsioses
0.660 0.340 0.000
A70-A74 Other diseases caused by chlamydiae
0.660 0.340 0.000
A65-A69 Other spirochaetal diseases
0.660 0.340 0.000
A20-A28 Certain zoonotic bacterial diseases
0.660 0.340 0.000
A15-A19 Tuberculosis
0.660 0.340 0.000
Z02 Examination and encounter for administrative purposes
0.660 0.340 0.000
Z72.1 Alcohol use
0.660 0.340 0.000
Z74 Problems related to care-provider dependency
0.660 0.340 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.659 0.341 0.000
M14 Arthropathies in other diseases classified elsewhere
0.658 0.341 0.000
M12 Other specific arthropathies
0.658 0.341 0.000
M11 Other crystal arthropathies
0.658 0.341 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.658 0.341 0.000
M08 Juvenile arthritis
0.658 0.341 0.000
N39 Other disorders of urinary system
0.659 0.341 0.000
I52 Other heart disorders in diseases classified elsewhere
0.658 0.342 0.000
I48 Atrial fibrillation and flutter
0.658 0.342 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.658 0.342 0.000
I41 Myocarditis in diseases classified elsewhere
0.658 0.342 0.000
I40 Acute myocarditis
0.658 0.342 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.658 0.342 0.000
I37 Pulmonary valve disorders
0.658 0.342 0.000
I36 Nonrheumatic tricuspid valve disorders
0.658 0.342 0.000
I32 Pericarditis in diseases classified elsewhere
0.658 0.342 0.000
N88.2 Stricture and stenosis of cervix uteri
0.656 0.344 0.000
Z84 Family history of other conditions
0.656 0.344 0.000
Z81 Family history of mental and behavioural disorders
0.656 0.344 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.654 0.346 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.654 0.346 0.000
E13 Other specified diabetes mellitus
0.654 0.346 0.000
E12 Malnutrition-related diabetes mellitus
0.654 0.346 0.000
S06 Intracranial injury
0.654 0.346 0.000
N92.4 Excessive bleeding in the premenopausal period
0.654 0.346 0.000
I31 Other diseases of pericardium
0.654 0.346 0.000
V80-V89 Other land transport accidents
0.653 0.347 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.653 0.347 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.652 0.348 0.000
K35.3 Acute appendicitis with localized peritonitis
0.652 0.348 0.000
M07 Psoriatic and enteropathic arthropathies
0.651 0.348 0.000
G47.9 Sleep disorder, unspecified
0.651 0.349 0.000
J43.8 Other emphysema
0.651 0.349 0.000
J43.2 Centrilobular emphysema
0.651 0.349 0.000
J43.1 Panlobular emphysema
0.651 0.349 0.000
J43.0 MacLeod's syndrome
0.651 0.349 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.651 0.349 0.000
H40 Glaucoma
0.651 0.349 0.000
Z99.3 Dependence on wheelchair
0.651 0.349 0.000
E27 Other disorders of adrenal gland
0.650 0.350 0.000
K72 Hepatic failure, not elsewhere classified
0.649 0.350 0.000
G47.4 Narcolepsy and cataplexy
0.649 0.351 0.000
G47.2 Disorders of the sleep-wake schedule
0.649 0.351 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.649 0.351 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.649 0.351 0.000
S51 Open wound of forearm
0.649 0.351 0.000
S09 Other and unspecified injuries of head
0.648 0.352 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.647 0.353 0.000
K76.6 Portal hypertension
0.647 0.353 0.000
T82.1 Mechanical complication of cardiac electronic device
0.647 0.353 0.000
H18 Other disorders of cornea
0.647 0.353 0.000
Z98.0 Intestinal bypass and anastomosis status
0.647 0.353 0.000
I45.8 Other specified conduction disorders
0.646 0.354 0.000
I45.5 Other specified heart block
0.646 0.354 0.000
I45.4 Nonspecific intraventricular block
0.646 0.354 0.000
I45.3 Trifascicular block
0.646 0.354 0.000
I45.0 Right fascicular block
0.646 0.354 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.646 0.354 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.644 0.356 0.000
N76 Other inflammation of vagina and vulva
0.644 0.356 0.000
K03 Other diseases of hard tissues of teeth
0.644 0.356 0.000
K00 Disorders of tooth development and eruption
0.644 0.356 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.643 0.356 0.000
N75 Diseases of Bartholin's gland
0.643 0.357 0.000
Z13 Special screening examination for other diseases and disorders
0.642 0.358 0.000
J69 Pneumonitis due to solids and liquids
0.641 0.359 0.000
Z90.1 Acquired absence of breast(s)
0.640 0.360 0.000
M19.0 Primary arthrosis of other joints
0.639 0.361 0.000
J18.8 Other pneumonia, organism unspecified
0.639 0.361 0.000
J18.2 Hypostatic pneumonia, unspecified
0.639 0.361 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.638 0.362 0.000
N84 Polyp of female genital tract
0.637 0.363 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.637 0.363 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.637 0.363 0.000
D55-D59 Haemolytic anaemias
0.636 0.363 0.000
M41 Scoliosis
0.636 0.363 0.000
K70.4 Alcoholic hepatic failure
0.636 0.364 0.000
S00 Superficial injury of head
0.636 0.364 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.636 0.364 0.000
S89 Other and unspecified injuries of lower leg
0.636 0.364 0.000
D80-D89 Certain disorders involving the immune mechanism
0.635 0.365 0.000
Y60.0 During surgical operation
0.635 0.365 0.000
K76.9 Liver disease, unspecified
0.634 0.366 0.000
K75.0 Abscess of liver
0.634 0.366 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.633 0.367 0.000
K75.2 Nonspecific reactive hepatitis
0.633 0.367 0.000
K75.1 Phlebitis of portal vein
0.633 0.367 0.000
Z73 Problems related to life-management difficulty
0.632 0.368 0.000
M24.0 Loose body in joint
0.632 0.368 0.000
N70 Salpingitis and oophoritis
0.631 0.368 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.631 0.369 0.000
W00-W19 Falls
0.631 0.369 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.631 0.369 0.000
K66.8 Other specified disorders of peritoneum
0.631 0.369 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.629 0.371 0.000
Z90.8 Acquired absence of other organs
0.629 0.371 0.000
E23 Hypofunction and other disorders of pituitary gland
0.629 0.371 0.000
E21.0 Primary hyperparathyroidism
0.629 0.371 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.629 0.371 0.000
K83 Other diseases of biliary tract
0.628 0.372 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.628 0.372 0.000
M21.0 Valgus deformity, not elsewhere classified
0.627 0.373 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.627 0.373 0.000
E34 Other endocrine disorders
0.627 0.373 0.000
E32 Diseases of thymus
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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