TreeWAS – Variant ID: rs78159609

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
# Top node	1.000	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	1.000	0.000
F10 Mental and behavioural disorders due to use of alcohol	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001
S00-S09 Injuries to the head	0.998	0.002
S80-S89 Injuries to the knee and lower leg	0.997	0.003
F10.1 Harmful use	0.997	0.003
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.988	0.012
T36-T50 Poisoning by drugs, medicaments and biological substances	0.987	0.013
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.987	0.013
S01 Open wound of head	0.986	0.014
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.981	0.019
Chapter VI Diseases of the nervous system	0.979	0.021
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.978	0.022
S82 Fracture of lower leg, including ankle	0.976	0.024
W00-W19 Falls	0.962	0.038
G20-G26 Extrapyramidal and movement disorders	0.950	0.050
F10.0 Acute intoxication	0.950	0.050
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.947	0.053
G20 Parkinson's disease	0.937	0.063
F10.2 Dependence syndrome	0.927	0.073
S70-S79 Injuries to the hip and thigh	0.920	0.080
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.909	0.091
T66-T78 Other and unspecified effects of external causes	0.908	0.092
S90-S99 Injuries to the ankle and foot	0.905	0.095
S01.8 Open wound of other parts of head	0.903	0.097
S81 Open wound of lower leg	0.902	0.098
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.899	0.101
S00 Superficial injury of head	0.898	0.102
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.891	0.109
Q20-Q28 Congenital malformations of the circulatory system	0.881	0.119
G00-G09 Inflammatory diseases of the central nervous system	0.880	0.120
S06 Intracranial injury	0.878	0.122
W19 Unspecified fall	0.878	0.122
Q60-Q64 Congenital malformations of the urinary system	0.872	0.128
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.871	0.129
S82.1 Fracture of upper end of tibia	0.870	0.130
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.867	0.133
G30-G32 Other degenerative diseases of the nervous system	0.867	0.133
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.866	0.134
S82.2 Fracture of shaft of tibia	0.862	0.138
F00-F09 Organic, including symptomatic, mental disorders	0.862	0.138
X60-X84 Intentional self-harm	0.856	0.144
W50-W64 Exposure to animate mechanical forces	0.856	0.144
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.853	0.147
G90-G99 Other disorders of the nervous system	0.852	0.148
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.846	0.154
Chapter XXII Codes for special purposes	0.844	0.156
S72 Fracture of femur	0.844	0.156
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.840	0.160
S01.1 Open wound of eyelid and periocular area	0.838	0.162
S01.9 Open wound of head, part unspecified	0.837	0.163
W13 Fall from, out of or through building or structure	0.837	0.163
F30-F39 Mood [affective] disorders	0.835	0.165
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.832	0.168
S01.0 Open wound of scalp	0.831	0.169
T78 Adverse effects, not elsewhere classified	0.829	0.171
S00.1 Contusion of eyelid and periocular area	0.826	0.174
T82.3 Mechanical complication of other vascular grafts	0.825	0.175
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.820	0.180
S01.3 Open wound of ear	0.819	0.181
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.818	0.182
V40-V49 Car occupant injured in transport accident	0.815	0.185
S81.8 Open wound of other parts of lower leg	0.813	0.187
F10.3 Withdrawal state	0.813	0.187
G04 Encephalitis, myelitis and encephalomyelitis	0.810	0.190
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.808	0.192
Q21 Congenital malformations of cardiac septa	0.807	0.193
S91 Open wound of ankle and foot	0.806	0.194
F60-F69 Disorders of adult personality and behaviour	0.806	0.194
S82.6 Fracture of lateral malleolus	0.805	0.195
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.805	0.195
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.804	0.196
S10-S19 Injuries to the neck	0.804	0.196
T84.1 Mechanical complication of internal fixation device of bones of limb	0.802	0.198
T20-T25 Burns and corrosions of external body surface, specified by site	0.800	0.200
T90 Sequelae of injuries of head	0.798	0.202
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.798	0.202
S82.10 Fracture of upper end of tibia (closed)	0.795	0.205
S01.2 Open wound of nose	0.793	0.207
Chapter I Certain infectious and parasitic diseases	0.787	0.213
S82.8 Fractures of other parts of lower leg	0.784	0.216
S50-S59 Injuries to the elbow and forearm	0.781	0.219
W20-W49 Exposure to inanimate mechanical forces	0.781	0.219
T92 Sequelae of injuries of upper limb	0.781	0.219
T82.0 Mechanical complication of heart valve prosthesis	0.780	0.220
F99-F99 Unspecified mental disorder	0.779	0.221
V80-V89 Other land transport accidents	0.779	0.221
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.779	0.221
S80 Superficial injury of lower leg	0.777	0.223
S82.3 Fracture of lower end of tibia	0.777	0.223
T91 Sequelae of injuries of neck and trunk	0.775	0.224
T51 Toxic effect of alcohol	0.774	0.226
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.774	0.226
T46 Poisoning by agents primarily affecting the cardiovascular system	0.771	0.229
T43.2 Other and unspecified antidepressants	0.771	0.229
S40-S49 Injuries to the shoulder and upper arm	0.770	0.229
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.769	0.231
S83.6 Sprain and strain of other and unspecified parts of knee	0.769	0.231
Q50-Q56 Congenital malformations of genital organs	0.768	0.232
S02 Fracture of skull and facial bones	0.768	0.232
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.766	0.234
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.764	0.236
Q61 Cystic kidney disease	0.763	0.236
T43.5 Other and unspecified antipsychotics and neuroleptics	0.763	0.237
F10.9 Unspecified mental and behavioural disorder	0.763	0.237
S06.6 Traumatic subarachnoid haemorrhage	0.760	0.240
Y40 Systemic antibiotics	0.759	0.241
G70-G73 Diseases of myoneural junction and muscle	0.757	0.243
X58-X59 Accidental exposure to other and unspecified factors	0.755	0.244
S71 Open wound of hip and thigh	0.754	0.246
G35-G37 Demyelinating diseases of the central nervous system	0.754	0.246
S82.5 Fracture of medial malleolus	0.753	0.247
W08 Fall involving other furniture	0.752	0.248
Y85 Sequelae of transport accidents	0.752	0.248
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.751	0.248
Y52 Agents primarily affecting the cardiovascular system	0.751	0.249
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.750	0.250
F80-F89 Disorders of psychological development	0.749	0.251
T79-T79 Certain early complications of trauma	0.749	0.251
T88 Other complications of surgical and medical care, not elsewhere classified	0.748	0.252
T80 Complications following infusion, transfusion and therapeutic injection	0.748	0.252
W13.9 Unspecified place	0.747	0.253
X40-X49 Accidental poisoning by and exposure to noxious substances	0.746	0.254
S05 Injury of eye and orbit	0.744	0.256
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.744	0.256
B35-B49 Mycoses	0.744	0.256
W19.2 School, other institution and public administrative area	0.743	0.257
W07 Fall involving chair	0.742	0.258
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.742	0.258
Q21.1 Atrial septal defect	0.741	0.259
F20 Schizophrenia	0.740	0.260
T93 Sequelae of injuries of lower limb	0.740	0.260
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.738	0.262
S01.7 Multiple open wounds of head	0.738	0.262
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.737	0.263
S83.2 Tear of meniscus, current	0.735	0.265
S82.20 Fracture of shaft of tibia (closed)	0.734	0.266
X20-X29 Contact with venomous animals and plants	0.732	0.267
G96 Other disorders of central nervous system	0.732	0.268
S81.9 Open wound of lower leg, part unspecified	0.731	0.269
W06 Fall involving bed	0.730	0.270
F11 Mental and behavioural disorders due to use of opioids	0.729	0.271
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.729	0.271
S89 Other and unspecified injuries of lower leg	0.728	0.272
G24 Dystonia	0.726	0.274
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.726	0.274
W19.1 Residential institution	0.725	0.275
Y49 Psychotropic drugs, not elsewhere classified	0.724	0.276
T78.3 Angioneurotic oedema	0.721	0.279
T98 Sequelae of other and unspecified effects of external causes	0.721	0.279
W19.4 Street and highway	0.719	0.281
F00 Dementia in Alzheimer's disease	0.719	0.281
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.719	0.281
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F10.8 Other mental and behavioural disorders	0.717	0.283
F10.7 Residual and late-onset psychotic disorder	0.717	0.283
F10.6 Amnesic syndrome	0.717	0.283
F10.5 Psychotic disorder	0.717	0.283
F18 Mental and behavioural disorders due to use of volatile solvents	0.717	0.283
F16 Mental and behavioural disorders due to use of hallucinogens	0.717	0.283
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.717	0.283
F14 Mental and behavioural disorders due to use of cocaine	0.717	0.283
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.716	0.283
Y10-Y34 Event of undetermined intent	0.716	0.283
Y00-Y09 Assault	0.716	0.283
X85-X99 Assault	0.716	0.283
X50-X57 Overexertion, travel and privation	0.716	0.283
X30-X39 Exposure to forces of nature	0.716	0.283
X10-X19 Contact with heat and hot substances	0.716	0.283
X00-X09 Exposure to smoke, fire and flames	0.716	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.283
W75-W84 Other accidental threats to breathing	0.716	0.283
W65-W74 Accidental drowning and submersion	0.716	0.283
V98-V99 Other and unspecified transport accidents	0.716	0.283
V95-V97 Air and space transport accidents	0.716	0.283
V90-V94 Water transport accidents	0.716	0.283
V70-V79 Bus occupant injured in transport accident	0.716	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.283
V01-V09 Pedestrian injured in transport accident	0.716	0.283
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.716	0.284
S08 Traumatic amputation of part of head	0.715	0.285
S07 Crushing injury of head	0.715	0.285
S04 Injury of cranial nerves	0.715	0.285
S03 Dislocation, sprain and strain of joints and ligaments of head	0.715	0.285
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.715	0.285
F29 Unspecified nonorganic psychosis	0.715	0.285
S88 Traumatic amputation of lower leg	0.715	0.285
S87 Crushing injury of lower leg	0.715	0.285
S85 Injury of blood vessels at lower leg level	0.715	0.285
S84 Injury of nerves at lower leg level	0.715	0.285
Q27 Other congenital malformations of peripheral vascular system	0.715	0.285
T78.2 Anaphylactic shock, unspecified	0.714	0.286
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.712	0.288
Y89 Sequelae of other external causes	0.712	0.288
W55 Bitten or struck by other mammals	0.711	0.289
G30 Alzheimer's disease	0.709	0.291
Y57 Other and unspecified drugs and medicaments	0.709	0.291
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.708	0.292
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.708	0.292
T41 Poisoning by anaesthetics and therapeutic gases	0.708	0.292
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.708	0.292
T36 Poisoning by systemic antibiotics	0.708	0.292
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.708	0.292
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.708	0.292
T82.4 Mechanical complication of vascular dialysis catheter	0.708	0.292
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.708	0.292
F03 Unspecified dementia	0.708	0.292
Q80-Q89 Other congenital malformations	0.707	0.293
S82.21 Fracture of shaft of tibia (open)	0.707	0.293
Y88 Sequelae of surgical and medical care as external cause	0.706	0.294
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.705	0.295
S86 Injury of muscle and tendon at lower leg level	0.704	0.296
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.701	0.299
Q35-Q37 Cleft lip and cleft palate	0.701	0.299
Q30-Q34 Congenital malformations of the respiratory system	0.701	0.299
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.299
S00.7 Multiple superficial injuries of head	0.701	0.299
Y43 Primarily systemic agents	0.700	0.300
S82.9 Fracture of lower leg, part unspecified	0.699	0.300
S82.7 Multiple fractures of lower leg	0.699	0.300
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.699	0.301
Q38-Q45 Other congenital malformations of the digestive system	0.699	0.301
Q00-Q07 Congenital malformations of the nervous system	0.698	0.302
S72.0 Fracture of neck of femur	0.697	0.303
B37 Candidiasis	0.697	0.303
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.696	0.304
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.696	0.304
S00.9 Superficial injury of head, part unspecified	0.695	0.305
S01.4 Open wound of cheek and temporomandibular area	0.695	0.305
W10 Fall on and from stairs and steps	0.694	0.305
T68 Hypothermia	0.694	0.306
Y85.9 Sequelae of other and unspecified transport accidents	0.693	0.306
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.693	0.307
Q63 Other congenital malformations of kidney	0.691	0.309
T40.2 Other opioids	0.691	0.309
W17 Other fall from one level to another	0.690	0.310
W16 Diving or jumping into water causing injury other than drowning or submersion	0.690	0.310
W15 Fall from cliff	0.690	0.310
W14 Fall from tree	0.690	0.310
W12 Fall on and from scaffolding	0.690	0.310
W11 Fall on and from ladder	0.690	0.310
W09 Fall involving playground equipment	0.690	0.310
W05 Fall involving wheelchair	0.690	0.310
W04 Fall while being carried or supported by other persons	0.690	0.310
W03 Other fall on same level due to collision with, or pushing by, another person	0.690	0.310
W01 Fall on same level from slipping, tripping and stumbling	0.690	0.310
W00 Fall on same level involving ice and snow	0.690	0.310
T82.1 Mechanical complication of cardiac electronic device	0.690	0.310
F12 Mental and behavioural disorders due to use of cannabinoids	0.689	0.310
T51.0 Ethanol	0.688	0.312
G91 Hydrocephalus	0.686	0.313
S72.1 Pertrochanteric fracture	0.686	0.314
S91.3 Open wound of other parts of foot	0.685	0.315
S90 Superficial injury of ankle and foot	0.685	0.315
T43.3 Phenothiazine antipsychotics and neuroleptics	0.684	0.316
Y48 Anaesthetics and therapeutic gases	0.683	0.316
F32 Depressive episode	0.683	0.317
S82.60 Fracture of lateral malleolus (closed)	0.683	0.317
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.682	0.318
S06.5 Traumatic subdural haemorrhage	0.682	0.318
G23 Other degenerative diseases of basal ganglia	0.681	0.318
G21 Secondary Parkinsonism	0.681	0.318
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.681	0.318
G22 Parkinsonism in diseases classified elsewhere	0.681	0.318
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.680	0.320
Y41 Other systemic anti-infectives and antiparasitics	0.679	0.321
T95 Sequelae of burns, corrosions and frostbite	0.679	0.321
T94 Sequelae of injuries involving multiple and unspecified body regions	0.679	0.321
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.679	0.321
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.679	0.321
V10-V19 Pedal cyclist injured in transport accident	0.678	0.321
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.675	0.325
T87 Complications peculiar to reattachment and amputation	0.674	0.326
T45.5 Anticoagulants	0.673	0.327
S91.1 Open wound of toe(s) without damage to nail	0.673	0.327
T40.4 Other synthetic narcotics	0.672	0.328
S00.2 Other superficial injuries of eyelid and periocular area	0.672	0.328
V20-V29 Motorcycle rider injured in transport accident	0.669	0.331
S00.5 Superficial injury of lip and oral cavity	0.669	0.331
W19.9 Unspecified place	0.668	0.332
W51 Striking against or bumped into by another person	0.668	0.332
S06.2 Diffuse brain injury	0.668	0.332
S79 Other and unspecified injuries of hip and thigh	0.667	0.332
F60 Specific personality disorders	0.667	0.333
S82.4 Fracture of fibula alone	0.666	0.334
Y95 Nosocomial condition	0.666	0.334
S42 Fracture of shoulder and upper arm	0.665	0.335
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.665	0.335
F19.1 Harmful use	0.663	0.336
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.662	0.338
S72.4 Fracture of lower end of femur	0.661	0.339
S78 Traumatic amputation of hip and thigh	0.659	0.340
S77 Crushing injury of hip and thigh	0.659	0.340
S76 Injury of muscle and tendon at hip and thigh level	0.659	0.340
S75 Injury of blood vessels at hip and thigh level	0.659	0.340
S74 Injury of nerves at hip and thigh level	0.659	0.340
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.659	0.340
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.658	0.342
V49 Car occupant injured in other and unspecified transport accidents	0.657	0.342
T23 Burn and corrosion of wrist and hand	0.657	0.342
Y52.4 Angiotensin-converting-enzyme inhibitors	0.654	0.346
U88 Agent resistant to multiple antibiotics	0.654	0.346
F30 Manic episode	0.654	0.346
Y60-Y69 Misadventures to patients during surgical and medical care	0.652	0.348
S83.7 Injury to multiple structures of knee	0.652	0.348
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.652	0.348
S83.3 Tear of articular cartilage of knee, current	0.652	0.348
S83.1 Dislocation of knee	0.652	0.348
S83.0 Dislocation of patella	0.652	0.348
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.652	0.348
T75 Effects of other external causes	0.651	0.349
T74 Maltreatment syndromes	0.651	0.349
T73 Effects of other deprivation	0.651	0.349
T70 Effects of air pressure and water pressure	0.651	0.349
T69 Other effects of reduced temperature	0.651	0.349
T67 Effects of heat and light	0.651	0.349
T71 Asphyxiation	0.651	0.349
T66 Unspecified effects of radiation	0.651	0.349
S99 Other and unspecified injuries of ankle and foot	0.649	0.351
S98 Traumatic amputation of ankle and foot	0.649	0.351
S97 Crushing injury of ankle and foot	0.649	0.351
S96 Injury of muscle and tendon at ankle and foot level	0.649	0.351
S95 Injury of blood vessels at ankle and foot level	0.649	0.351
S94 Injury of nerves at ankle and foot level	0.649	0.351
T86 Failure and rejection of transplanted organs and tissues	0.648	0.351
S06.0 Concussion	0.648	0.352
T09 Other injuries of spine and trunk, level unspecified	0.647	0.352
T90.2 Sequelae of fracture of skull and facial bones	0.647	0.353
S81.7 Multiple open wounds of lower leg	0.646	0.354
B37.9 Candidiasis, unspecified	0.646	0.354
S82.80 Fractures of other parts of lower leg (closed)	0.646	0.354
F01 Vascular dementia	0.645	0.355
F10.4 Withdrawal state with delirium	0.645	0.355
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.645	0.355
Y59 Other and unspecified vaccines and biological substances	0.645	0.355
Y58 Bacterial vaccines	0.645	0.355
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.645	0.355
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.645	0.355
Y53 Agents primarily affecting the gastro-intestinal system	0.645	0.355
Y50 Central nervous system stimulants, not elsewhere classified	0.645	0.355
Y47 Sedatives, hypnotics and antianxiety drugs	0.645	0.355
Y46 Antiepileptics and anti-Parkinsonism drugs	0.645	0.355
S72.3 Fracture of shaft of femur	0.644	0.356
S52 Fracture of forearm	0.644	0.356
S00.4 Superficial injury of ear	0.643	0.356
G37 Other demyelinating diseases of central nervous system	0.643	0.357
A30-A49 Other bacterial diseases	0.643	0.357
G90 Disorders of autonomic nervous system	0.642	0.358
W18 Other fall on same level	0.640	0.359
T14 Injury of unspecified body region	0.640	0.360
F17 Mental and behavioural disorders due to use of tobacco	0.640	0.360
T92.2 Sequelae of fracture at wrist and hand level	0.639	0.361
T43.9 Psychotropic drug, unspecified	0.639	0.361
T43.8 Other psychotropic drugs, not elsewhere classified	0.639	0.361
T43.6 Psychostimulants with abuse potential	0.639	0.361
T43.4 Butyrophenone and thioxanthene neuroleptics	0.639	0.361
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.639	0.361
S49 Other and unspecified injuries of shoulder and upper arm	0.639	0.361
Y79 Orthopaedic devices associated with adverse incidents	0.638	0.362
F22 Persistent delusional disorders	0.636	0.363
Q60 Renal agenesis and other reduction defects of kidney	0.636	0.364
S71.1 Open wound of thigh	0.636	0.364
S72.2 Subtrochanteric fracture	0.635	0.365
T93.1 Sequelae of fracture of femur	0.634	0.366
S82.30 Fracture of lower end of tibia (closed)	0.634	0.366
T88.5 Other complications of anaesthesia	0.633	0.367
S80.0 Contusion of knee	0.633	0.367
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.633	0.367
Q26 Congenital malformations of great veins	0.632	0.368
Q25 Congenital malformations of great arteries	0.632	0.368
Q24 Other congenital malformations of heart	0.632	0.368
Q22 Congenital malformations of pulmonary and tricuspid valves	0.632	0.368
Q20 Congenital malformations of cardiac chambers and connexions	0.632	0.368
T45.0 Antiallergic and antiemetic drugs	0.631	0.369
G06 Intracranial and intraspinal abscess and granuloma	0.631	0.369
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.631	0.369
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.631	0.369
G00 Bacterial meningitis, not elsewhere classified	0.631	0.369
G09 Sequelae of inflammatory diseases of central nervous system	0.631	0.369
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.631	0.369
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.631	0.369
G01 Meningitis in bacterial diseases classified elsewhere	0.631	0.369
S06.9 Intracranial injury, unspecified	0.630	0.370
S06.8 Other intracranial injuries	0.630	0.370
S06.7 Intracranial injury with prolonged coma	0.630	0.370
S06.4 Epidural haemorrhage	0.630	0.370
S06.1 Traumatic cerebral oedema	0.630	0.370
W19.8 Other specified place	0.630	0.370
W19.5 Trade and service area	0.630	0.370
W19.0 Home	0.630	0.370
W19.7 Farm	0.630	0.370
W19.6 Industrial and construction area	0.630	0.370
S09 Other and unspecified injuries of head	0.627	0.373
Q64 Other congenital malformations of urinary system	0.625	0.375
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.625	0.375
Q61.9 Cystic kidney disease, unspecified	0.624	0.376
F28 Other nonorganic psychotic disorders	0.624	0.376
F24 Induced delusional disorder	0.624	0.376
F21 Schizotypal disorder	0.624	0.376
S82.11 Fracture of upper end of tibia (open)	0.624	0.376
G03 Meningitis due to other and unspecified causes	0.624	0.376
G31.8 Other specified degenerative diseases of nervous system	0.623	0.377
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.623	0.377
Q21.0 Ventricular septal defect	0.623	0.377
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.623	0.377
Q18 Other congenital malformations of face and neck	0.622	0.378
V48 Car occupant injured in noncollision transport accident	0.622	0.378
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.622	0.378
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.622	0.378
S20-S29 Injuries to the thorax	0.622	0.378
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.622	0.378
G97.1 Other reaction to spinal and lumbar puncture	0.621	0.379
X78 Intentional self-harm by sharp object	0.621	0.379
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.621	0.379
T65 Toxic effect of other and unspecified substances	0.621	0.379
T62 Toxic effect of other noxious substances eaten as food	0.621	0.379
T61 Toxic effect of noxious substances eaten as seafood	0.621	0.379
T60 Toxic effect of pesticides	0.621	0.379
T57 Toxic effect of other inorganic substances	0.621	0.379
T56 Toxic effect of metals	0.621	0.379
T54 Toxic effect of corrosive substances	0.621	0.379
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.621	0.379
T52 Toxic effect of organic solvents	0.621	0.379
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.621	0.379
T58 Toxic effect of carbon monoxide	0.621	0.379
T55 Toxic effect of soaps and detergents	0.621	0.379
F99 Mental disorder, not otherwise specified	0.621	0.379
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.619	0.380
S82.0 Fracture of patella	0.619	0.381
T59 Toxic effect of other gases, fumes and vapours	0.619	0.381
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.618	0.382
F02 Dementia in other diseases classified elsewhere	0.618	0.382
F09 Unspecified organic or symptomatic mental disorder	0.618	0.382
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.618	0.382
F25 Schizoaffective disorders	0.617	0.382
F00.9 Dementia in Alzheimer's disease, unspecified	0.617	0.383
T46.1 Calcium-channel blockers	0.617	0.383
G80-G83 Cerebral palsy and other paralytic syndromes	0.616	0.384
S12 Fracture of neck	0.616	0.384
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.615	0.385
X84 Intentional self-harm by unspecified means	0.614	0.386
X83 Intentional self-harm by other specified means	0.614	0.386
X82 Intentional self-harm by crashing of motor vehicle	0.614	0.386
X81 Intentional self-harm by jumping or lying before moving object	0.614	0.386
X80 Intentional self-harm by jumping from a high place	0.614	0.386
X79 Intentional self-harm by blunt object	0.614	0.386
X77 Intentional self-harm by steam, hot vapours and hot objects	0.614	0.386
X76 Intentional self-harm by smoke, fire and flames	0.614	0.386
X75 Intentional self-harm by explosive material	0.614	0.386
X74 Intentional self-harm by other and unspecified firearm discharge	0.614	0.386
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.614	0.386
X72 Intentional self-harm by handgun discharge	0.614	0.386
X71 Intentional self-harm by drowning and submersion	0.614	0.386
X70 Intentional self-harm by hanging, strangulation and suffocation	0.614	0.386
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.614	0.386
X68 Intentional self-poisoning by and exposure to pesticides	0.614	0.386
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.614	0.386
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.614	0.386
X65 Intentional self-poisoning by and exposure to alcohol	0.614	0.386
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.614	0.386
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.614	0.386
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.614	0.386
W64 Exposure to other and unspecified animate mechanical forces	0.613	0.386
W60 Contact with plant thorns and spines and sharp leaves	0.613	0.386
W59 Bitten or crushed by other reptiles	0.613	0.386
W58 Bitten or struck by crocodile or alligator	0.613	0.386
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.613	0.386
W56 Contact with marine animal	0.613	0.386
W54 Bitten or struck by dog	0.613	0.386
W53 Bitten by rat	0.613	0.386
W52 Crushed, pushed and stepped on by crowd or human stampede	0.613	0.386
T90.9 Sequelae of unspecified injury of head	0.613	0.387
Q61.3 Polycystic kidney, unspecified	0.613	0.387
T63 Toxic effect of contact with venomous animals	0.612	0.388
W20 Struck by thrown, projected or falling object	0.612	0.388
G94 Other disorders of brain in diseases classified elsewhere	0.611	0.389
G98 Other disorders of nervous system, not elsewhere classified	0.611	0.389
G92 Toxic encephalopathy	0.611	0.389
G97.8 Other postprocedural disorders of nervous system	0.611	0.389
Q76 Congenital malformations of spine and bony thorax	0.610	0.390
T91.8 Sequelae of other specified injuries of neck and trunk	0.609	0.391
T51.9 Alcohol, unspecified	0.608	0.392
F05 Delirium, not induced by alcohol and other psychoactive substances	0.608	0.392
W55.8 Other specified place	0.608	0.392
S92 Fracture of foot, except ankle	0.607	0.393
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.607	0.393
T42.5 Mixed antiepileptics, not elsewhere classified	0.607	0.393
T42.3 Barbiturates	0.607	0.393
T42.2 Succinimides and oxazolidinediones	0.607	0.393

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations