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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78165376
log Bayes Factor = 8.53544
Chromosome 3   position 177,552,699  (GRCh37) Explore rs78165376 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.996 0.004 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
M45-M49 Spondylopathies
0.992 0.008 0.000
M47 Spondylosis
0.991 0.009 0.000
M47.8 Other spondylosis
0.990 0.010 0.000
I27 Other pulmonary heart diseases
0.990 0.010 0.000
S60-S69 Injuries to the wrist and hand
0.988 0.012 0.000
K70-K77 Diseases of liver
0.985 0.015 0.000
M47.82 Other spondylosis (Cervical region)
0.981 0.019 0.000
S02 Fracture of skull and facial bones
0.977 0.023 0.000
I27.0 Primary pulmonary hypertension
0.977 0.023 0.000
I26 Pulmonary embolism
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.972 0.028 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.968 0.032 0.000
K70 Alcoholic liver disease
0.968 0.032 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.965 0.035 0.000
K76 Other diseases of liver
0.960 0.040 0.000
W00-W19 Falls
0.960 0.040 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.959 0.041 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.958 0.042 0.000
S09 Other and unspecified injuries of head
0.954 0.046 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.951 0.049 0.000
M86-M90 Other osteopathies
0.948 0.052 0.000
W19 Unspecified fall
0.941 0.059 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.941 0.059 0.000
K76.9 Liver disease, unspecified
0.937 0.063 0.000
K70.9 Alcoholic liver disease, unspecified
0.932 0.068 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.927 0.073 0.000
K50-K52 Noninfective enteritis and colitis
0.924 0.076 0.000
K74 Fibrosis and cirrhosis of liver
0.923 0.077 0.000
Y40 Systemic antibiotics
0.922 0.078 0.000
K76.6 Portal hypertension
0.922 0.078 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.917 0.083 0.000
S60 Superficial injury of wrist and hand
0.914 0.086 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.911 0.089 0.000
S09.9 Unspecified injury of head
0.910 0.090 0.000
Y42.5 Other oestrogens and progestogens
0.900 0.100 0.000
W19.2 School, other institution and public administrative area
0.897 0.103 0.000
M80-M85 Disorders of bone density and structure
0.893 0.107 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.892 0.108 0.000
R50-R69 General symptoms and signs
0.889 0.111 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
K75 Other inflammatory liver diseases
0.886 0.114 0.000
R94 Abnormal results of function studies
0.886 0.114 0.000
K51 Ulcerative colitis
0.883 0.117 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.880 0.120 0.000
M47.89 Other spondylosis (Site unspecified)
0.879 0.121 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.876 0.124 0.000
Y40.8 Other systemic antibiotics
0.873 0.127 0.000
I27.2 Other secondary pulmonary hypertension
0.868 0.132 0.000
I30-I52 Other forms of heart disease
0.865 0.135 0.000
S02.2 Fracture of nasal bones
0.862 0.138 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.861 0.139 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.860 0.140 0.000
M47.86 Other spondylosis (Lumbar region)
0.857 0.143 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.856 0.143 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.855 0.145 0.000
S02.4 Fracture of malar and maxillary bones
0.854 0.146 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.852 0.148 0.000
S50-S59 Injuries to the elbow and forearm
0.852 0.148 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.851 0.149 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.851 0.149 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.851 0.149 0.000
R94.5 Abnormal results of liver function studies
0.849 0.151 0.000
S90-S99 Injuries to the ankle and foot
0.848 0.152 0.000
I42 Cardiomyopathy
0.844 0.156 0.000
M50-M54 Other dorsopathies
0.841 0.159 0.000
K72 Hepatic failure, not elsewhere classified
0.838 0.162 0.000
T98 Sequelae of other and unspecified effects of external causes
0.837 0.163 0.000
K74.3 Primary biliary cirrhosis
0.837 0.163 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
S02.8 Fractures of other skull and facial bones
0.836 0.164 0.000
Y52 Agents primarily affecting the cardiovascular system
0.836 0.164 0.000
R60 Oedema, not elsewhere classified
0.835 0.165 0.000
V40-V49 Car occupant injured in transport accident
0.832 0.168 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.829 0.171 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.829 0.171 0.000
I38 Endocarditis, valve unspecified
0.826 0.174 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.825 0.175 0.000
T00-T07 Injuries involving multiple body regions
0.825 0.175 0.000
S05 Injury of eye and orbit
0.820 0.180 0.000
I95 Hypotension
0.820 0.180 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.819 0.181 0.000
M46 Other inflammatory spondylopathies
0.818 0.182 0.000
M81 Osteoporosis without pathological fracture
0.816 0.184 0.000
R94.3 Abnormal results of cardiovascular function studies
0.815 0.185 0.000
S61 Open wound of wrist and hand
0.814 0.186 0.000
S10-S19 Injuries to the neck
0.813 0.187 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.813 0.187 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.812 0.188 0.000
A00-A09 Intestinal infectious diseases
0.812 0.188 0.000
K70.4 Alcoholic hepatic failure
0.808 0.192 0.000
R47-R49 Symptoms and signs involving speech and voice
0.807 0.193 0.000
K73 Chronic hepatitis, not elsewhere classified
0.805 0.195 0.000
M86 Osteomyelitis
0.804 0.196 0.000
S00 Superficial injury of head
0.804 0.196 0.000
M90 Osteopathies in diseases classified elsewhere
0.803 0.197 0.000
K50 Crohn's disease [regional enteritis]
0.802 0.198 0.000
R60.0 Localised oedema
0.801 0.199 0.000
M50 Cervical disk disorders
0.801 0.199 0.000
X60-X84 Intentional self-harm
0.800 0.200 0.000
Y43 Primarily systemic agents
0.796 0.204 0.000
T31 Burns classified according to extent of body surface involved
0.795 0.205 0.000
I80 Phlebitis and thrombophlebitis
0.795 0.205 0.000
T93 Sequelae of injuries of lower limb
0.794 0.206 0.000
R54 Senility
0.792 0.208 0.000
A30-A49 Other bacterial diseases
0.792 0.208 0.000
M88 Paget's disease of bone [osteitis deformans]
0.791 0.208 0.000
S40-S49 Injuries to the shoulder and upper arm
0.791 0.209 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.789 0.211 0.000
I28 Other diseases of pulmonary vessels
0.788 0.212 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.787 0.213 0.000
K70.3 Alcoholic cirrhosis of liver
0.786 0.214 0.000
T20 Burn and corrosion of head and neck
0.786 0.214 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.786 0.214 0.000
M91-M94 Chondropathies
0.785 0.215 0.000
R57 Shock, not elsewhere classified
0.784 0.216 0.000
Q60-Q64 Congenital malformations of the urinary system
0.784 0.216 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.783 0.217 0.000
W19.3 Sports and athletics area
0.782 0.217 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.782 0.218 0.000
S02.20 Fracture of nasal bones (closed)
0.780 0.220 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.780 0.220 0.000
T91 Sequelae of injuries of neck and trunk
0.779 0.221 0.000
K74.6 Other and unspecified cirrhosis of liver
0.778 0.222 0.000
R63 Symptoms and signs concerning food and fluid intake
0.777 0.223 0.000
K75.8 Other specified inflammatory liver diseases
0.776 0.224 0.000
R55 Syncope and collapse
0.776 0.224 0.000
S09.8 Other specified injuries of head
0.772 0.227 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.772 0.228 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.772 0.228 0.000
M47.1 Other spondylosis with myelopathy
0.772 0.228 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.768 0.232 0.000
S68 Traumatic amputation of wrist and hand
0.768 0.232 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.768 0.232 0.000
M00-M03 Infectious arthropathies
0.766 0.234 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.765 0.235 0.000
W50-W64 Exposure to animate mechanical forces
0.764 0.236 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.764 0.236 0.000
M47.84 Other spondylosis (Thoracic region)
0.762 0.238 0.000
I95.9 Hypotension, unspecified
0.762 0.238 0.000
T23 Burn and corrosion of wrist and hand
0.760 0.240 0.000
A04 Other bacterial intestinal infections
0.760 0.240 0.000
T90 Sequelae of injuries of head
0.760 0.240 0.000
M50.3 Other cervical disk degeneration
0.760 0.240 0.000
M47.9 Spondylosis, unspecified
0.759 0.241 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.759 0.241 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.759 0.241 0.000
W14 Fall from tree
0.759 0.241 0.000
T21 Burn and corrosion of trunk
0.759 0.241 0.000
Y48 Anaesthetics and therapeutic gases
0.758 0.242 0.000
W19.4 Street and highway
0.758 0.242 0.000
K51.5 Mucosal proctocolitis
0.758 0.242 0.000
W20-W49 Exposure to inanimate mechanical forces
0.757 0.243 0.000
K75.4 Autoimmune hepatitis
0.756 0.244 0.000
Y54.3 Benzothiadiazine derivatives
0.755 0.245 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.753 0.247 0.000
R47 Speech disturbances, not elsewhere classified
0.752 0.248 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.751 0.249 0.000
K51.4 Pseudopolyposis of colon
0.750 0.250 0.000
Q50-Q56 Congenital malformations of genital organs
0.750 0.250 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.750 0.250 0.000
M89 Other disorders of bone
0.750 0.250 0.000
S02.6 Fracture of mandible
0.749 0.251 0.000
Chapter VI Diseases of the nervous system
0.749 0.251 0.000
A41 Other septicaemia
0.748 0.252 0.000
I42.9 Cardiomyopathy, unspecified
0.747 0.253 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.747 0.253 0.000
V80-V89 Other land transport accidents
0.747 0.253 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.747 0.253 0.000
S36 Injury of intra-abdominal organs
0.747 0.253 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.745 0.254 0.000
I27.8 Other specified pulmonary heart diseases
0.745 0.255 0.000
S02.3 Fracture of orbital floor
0.744 0.256 0.000
R68 Other general symptoms and signs
0.743 0.257 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.743 0.257 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.743 0.257 0.000
I49 Other cardiac arrhythmias
0.743 0.257 0.000
S60.8 Other superficial injuries of wrist and hand
0.742 0.258 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.741 0.259 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.740 0.260 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.739 0.261 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.739 0.261 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.738 0.262 0.000
S37 Injury of urinary and pelvic organs
0.737 0.263 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.736 0.264 0.000
I27.9 Pulmonary heart disease, unspecified
0.736 0.264 0.000
K70.1 Alcoholic hepatitis
0.735 0.265 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.734 0.266 0.000
I42.0 Dilated cardiomyopathy
0.734 0.266 0.000
M81.9 Osteoporosis, unspecified
0.734 0.266 0.000
T31.0 Burns involving less than 10% of body surface
0.734 0.266 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.732 0.268 0.000
Y45.0 Opioids and related analgesics
0.730 0.270 0.000
S61.0 Open wound of finger(s) without damage to nail
0.730 0.270 0.000
S65 Injury of blood vessels at wrist and hand level
0.730 0.270 0.000
R52 Pain, not elsewhere classified
0.730 0.270 0.000
R42 Dizziness and giddiness
0.729 0.271 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.729 0.271 0.000
I85 Oesophageal varices
0.728 0.272 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.725 0.275 0.000
M60-M63 Disorders of muscles
0.723 0.277 0.000
S80-S89 Injuries to the knee and lower leg
0.723 0.277 0.000
Chapter X Diseases of the respiratory system
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.722 0.278 0.000
W19.1 Residential institution
0.722 0.278 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.721 0.279 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.721 0.279 0.000
K50.8 Other Crohn's disease
0.720 0.280 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.719 0.281 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Y59 Other and unspecified vaccines and biological substances
0.716 0.284 0.000
Y58 Bacterial vaccines
0.716 0.284 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.716 0.284 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.716 0.284 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.715 0.285 0.000
I34 Nonrheumatic mitral valve disorders
0.715 0.285 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
S40 Superficial injury of shoulder and upper arm
0.714 0.286 0.000
K74.5 Biliary cirrhosis, unspecified
0.713 0.287 0.000
M49 Spondylopathies in diseases classified elsewhere
0.711 0.288 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
B35-B49 Mycoses
0.711 0.289 0.000
M40-M43 Deforming dorsopathies
0.710 0.290 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.710 0.290 0.000
I05-I09 Chronic rheumatic heart diseases
0.710 0.290 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.709 0.290 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.709 0.290 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.709 0.290 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.709 0.290 0.000
I27.1 Kyphoscoliotic heart disease
0.709 0.290 0.000
X59 Exposure to unspecified factor
0.709 0.291 0.000
K77 Liver disorders in diseases classified elsewhere
0.706 0.294 0.000
K71 Toxic liver disease
0.706 0.294 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.706 0.294 0.000
S02.1 Fracture of base of skull
0.705 0.295 0.000
R47.0 Dysphasia and aphasia
0.704 0.296 0.000
I31 Other diseases of pericardium
0.703 0.297 0.000
W10 Fall on and from stairs and steps
0.701 0.299 0.000
Q27 Other congenital malformations of peripheral vascular system
0.701 0.299 0.000
S02.7 Multiple fractures involving skull and facial bones
0.700 0.299 0.000
M90.7 Fracture of bone in neoplastic disease
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
S30.0 Contusion of lower back and pelvis
0.696 0.304 0.000
K90-K93 Other diseases of the digestive system
0.696 0.304 0.000
M84 Disorders of continuity of bone
0.696 0.304 0.000
S67 Crushing injury of wrist and hand
0.696 0.304 0.000
G90-G99 Other disorders of the nervous system
0.696 0.304 0.000
R94.4 Abnormal results of kidney function studies
0.694 0.305 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.694 0.306 0.000
Y42.9 Other and unspecified hormone antagonists
0.694 0.306 0.000
Y42.4 Oral contraceptives
0.694 0.306 0.000
Y42.2 Antithyroid drugs
0.694 0.306 0.000
Y42.1 Thyroid hormones and substitutes
0.694 0.306 0.000
Q21 Congenital malformations of cardiac septa
0.694 0.306 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.694 0.306 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.694 0.306 0.000
S50 Superficial injury of forearm
0.693 0.307 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.692 0.308 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.692 0.308 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.692 0.308 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.692 0.308 0.000
S31 Open wound of abdomen, lower back and pelvis
0.692 0.308 0.000
K72.0 Acute and subacute hepatic failure
0.691 0.309 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.691 0.309 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.691 0.309 0.000
Y57 Other and unspecified drugs and medicaments
0.690 0.310 0.000
W18 Other fall on same level
0.689 0.310 0.000
R50 Fever of unknown origin
0.689 0.311 0.000
K76.5 Hepatic veno-occlusive disease
0.688 0.311 0.000
K76.4 Peliosis hepatis
0.688 0.311 0.000
K76.3 Infarction of liver
0.688 0.311 0.000
K76.2 Central haemorrhagic necrosis of liver
0.688 0.311 0.000
K76.1 Chronic passive congestion of liver
0.688 0.311 0.000
Q24 Other congenital malformations of heart
0.688 0.311 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.688 0.312 0.000
W15 Fall from cliff
0.688 0.312 0.000
W12 Fall on and from scaffolding
0.688 0.312 0.000
W11 Fall on and from ladder
0.688 0.312 0.000
W09 Fall involving playground equipment
0.688 0.312 0.000
W05 Fall involving wheelchair
0.688 0.312 0.000
W04 Fall while being carried or supported by other persons
0.688 0.312 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.688 0.312 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.688 0.312 0.000
W00 Fall on same level involving ice and snow
0.688 0.312 0.000
A04.5 Campylobacter enteritis
0.688 0.312 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.687 0.312 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.687 0.312 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.687 0.312 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.687 0.312 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.687 0.312 0.000
S19 Other and unspecified injuries of neck
0.687 0.313 0.000
W19.9 Unspecified place
0.687 0.313 0.000
T95 Sequelae of burns, corrosions and frostbite
0.687 0.313 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.687 0.313 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.687 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.313 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.313 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.313 0.000
S00.5 Superficial injury of lip and oral cavity
0.687 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.685 0.315 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.685 0.315 0.000
S09.7 Multiple injuries of head
0.684 0.316 0.000
S09.2 Traumatic rupture of ear drum
0.684 0.316 0.000
S09.1 Injury of muscle and tendon of head
0.684 0.316 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.684 0.316 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.684 0.316 0.000
M53 Other dorsopathies, not elsewhere classified
0.684 0.316 0.000
K76.7 Hepatorenal syndrome
0.684 0.316 0.000
R57.2 Septic shock
0.683 0.317 0.000
Chapter XXII Codes for special purposes
0.683 0.317 0.000
X78 Intentional self-harm by sharp object
0.682 0.318 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.682 0.318 0.000
W08 Fall involving other furniture
0.681 0.319 0.000
Q28 Other congenital malformations of circulatory system
0.681 0.319 0.000
S60.2 Contusion of other parts of wrist and hand
0.681 0.319 0.000
S51 Open wound of forearm
0.680 0.320 0.000
M88.9 Paget's disease of bone, unspecified
0.679 0.321 0.000
S00.4 Superficial injury of ear
0.679 0.321 0.000
R63.0 Anorexia
0.678 0.322 0.000
M86.9 Osteomyelitis, unspecified
0.676 0.324 0.000
S89 Other and unspecified injuries of lower leg
0.676 0.324 0.000
T20.2 Burn of second degree of head and neck
0.675 0.325 0.000
R45 Symptoms and signs involving emotional state
0.675 0.325 0.000
W19.8 Other specified place
0.674 0.326 0.000
W19.5 Trade and service area
0.674 0.326 0.000
W19.0 Home
0.674 0.326 0.000
W19.7 Farm
0.674 0.326 0.000
W19.6 Industrial and construction area
0.674 0.326 0.000
T25 Burn and corrosion of ankle and foot
0.674 0.326 0.000
M87 Osteonecrosis
0.673 0.327 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.672 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.672 0.327 0.000
M50.8 Other cervical disk disorders
0.672 0.328 0.000
M85 Other disorders of bone density and structure
0.672 0.328 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.671 0.329 0.000
S54 Injury of nerves at forearm level
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.671 0.329 0.000
W13 Fall from, out of or through building or structure
0.670 0.330 0.000
M50.0 Cervical disk disorder with myelopathy
0.670 0.330 0.000
K70.0 Alcoholic fatty liver
0.670 0.330 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.669 0.331 0.000
S64 Injury of nerves at wrist and hand level
0.669 0.331 0.000
Y86 Sequelae of other accidents
0.669 0.331 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.668 0.332 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
W17 Other fall from one level to another
0.667 0.333 0.000
R64 Cachexia
0.667 0.333 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.333 0.000
K72.9 Hepatic failure, unspecified
0.666 0.334 0.000
S32 Fracture of lumbar spine and pelvis
0.665 0.335 0.000
S00.8 Superficial injury of other parts of head
0.663 0.337 0.000
B44 Aspergillosis
0.662 0.338 0.000
K74.4 Secondary biliary cirrhosis
0.662 0.338 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.662 0.338 0.000
K74.1 Hepatic sclerosis
0.662 0.338 0.000
R58 Haemorrhage, not elsewhere classified
0.661 0.339 0.000
Y40.7 Antifungal antibiotics, systemically used
0.661 0.339 0.000
Y40.6 Rifamycins
0.661 0.339 0.000
Y40.5 Aminoglycosides
0.661 0.339 0.000
Y40.4 Tetracyclines
0.661 0.339 0.000
Y40.2 Chloramphenicol group
0.661 0.339 0.000
Y85 Sequelae of transport accidents
0.660 0.340 0.000
T01 Open wounds involving multiple body regions
0.658 0.342 0.000
T92 Sequelae of injuries of upper limb
0.657 0.343 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.657 0.343 0.000
A15-A19 Tuberculosis
0.656 0.344 0.000
S60.7 Multiple superficial injuries of wrist and hand
0.655 0.345 0.000
S60.1 Contusion of finger(s) with damage to nail
0.655 0.345 0.000
S60.0 Contusion of finger(s) without damage to nail
0.655 0.345 0.000
Y65 Other misadventures during surgical and medical care
0.655 0.345 0.000
R52.0 Acute pain
0.654 0.346 0.000
Y45.2 Propionic acid derivatives
0.654 0.346 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.653 0.347 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.653 0.347 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.653 0.347 0.000
S06 Intracranial injury
0.652 0.347 0.000
R87 Abnormal findings in specimens from female genital organs
0.652 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
M45 Ankylosing spondylitis
0.651 0.349 0.000
I46 Cardiac arrest
0.649 0.351 0.000
I49.8 Other specified cardiac arrhythmias
0.649 0.351 0.000
T02 Fractures involving multiple body regions
0.649 0.351 0.000
M89.8 Other specified disorders of bone
0.649 0.351 0.000
I42.8 Other cardiomyopathies
0.648 0.352 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.647 0.353 0.000
Q80-Q89 Other congenital malformations
0.647 0.353 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.647 0.353 0.000
K51.2 Ulcerative (chronic) proctitis
0.646 0.354 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.646 0.354 0.000
M20-M25 Other joint disorders
0.646 0.354 0.000
S99 Other and unspecified injuries of ankle and foot
0.646 0.354 0.000
I95.8 Other hypotension
0.645 0.355 0.000
W07 Fall involving chair
0.645 0.355 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.645 0.355 0.000
A80-A89 Viral infections of the central nervous system
0.644 0.356 0.000
I31.9 Disease of pericardium, unspecified
0.643 0.357 0.000
S20-S29 Injuries to the thorax
0.642 0.357 0.000
S89.9 Unspecified injury of lower leg
0.642 0.358 0.000
S30.1 Contusion of abdominal wall
0.641 0.359 0.000
Y45.5 4-Aminophenol derivatives
0.641 0.359 0.000
M83 Adult osteomalacia
0.640 0.360 0.000
M94 Other disorders of cartilage
0.640 0.360 0.000
J30-J39 Other diseases of upper respiratory tract
0.639 0.361 0.000
I28.8 Other specified diseases of pulmonary vessels
0.638 0.362 0.000
R62 Lack of expected normal physiological development
0.638 0.362 0.000
B99-B99 Other infectious diseases
0.637 0.362 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.637 0.363 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.637 0.363 0.000
B50-B64 Protozoal diseases
0.637 0.363 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.637 0.363 0.000
A75-A79 Rickettsioses
0.637 0.363 0.000
A70-A74 Other diseases caused by chlamydiae
0.637 0.363 0.000
A65-A69 Other spirochaetal diseases
0.637 0.363 0.000
A20-A28 Certain zoonotic bacterial diseases
0.637 0.363 0.000
I42.6 Alcoholic cardiomyopathy
0.637 0.363 0.000
M81.0 Postmenopausal osteoporosis
0.636 0.363 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.636 0.364 0.000
I86 Varicose veins of other sites
0.636 0.364 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.636 0.364 0.000
K75.2 Nonspecific reactive hepatitis
0.636 0.364 0.000
K75.1 Phlebitis of portal vein
0.636 0.364 0.000
R94.7 Abnormal results of other endocrine function studies
0.635 0.365 0.000
R94.6 Abnormal results of thyroid function studies
0.635 0.365 0.000
R94.2 Abnormal results of pulmonary function studies
0.635 0.365 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.635 0.365 0.000
R94.0 Abnormal results of function studies of central nervous system
0.635 0.365 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.635 0.365 0.000
K50.0 Crohn's disease of small intestine
0.635 0.365 0.000
Y45.1 Salicylates
0.635 0.365 0.000
Y43.1 Antineoplastic antimetabolites
0.633 0.366 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.633 0.367 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.633 0.367 0.000
S63.6 Sprain and strain of finger(s)
0.632 0.368 0.000
T32 Corrosions classified according to extent of body surface involved
0.631 0.369 0.000
T30 Burn and corrosion, body region unspecified
0.631 0.369 0.000
T29 Burns and corrosions of multiple body regions
0.631 0.369 0.000
Y43.0 Antiallergic and antiemetic drugs
0.631 0.369 0.000
Y40.3 Macrolides
0.631 0.369 0.000
K75.0 Abscess of liver
0.630 0.369 0.000
Y42.7 Androgens and anabolic congeners
0.630 0.370 0.000
S00.0 Superficial injury of scalp
0.629 0.370 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.628 0.372 0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis
0.628 0.372 0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)
0.628 0.372 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.628 0.372 0.000
T21.2 Burn of second degree of trunk
0.628 0.372 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.628 0.372 0.000
A40 Streptococcal septicaemia
0.628 0.372 0.000
G90 Disorders of autonomic nervous system
0.628 0.372 0.000
S40.0 Contusion of shoulder and upper arm
0.628 0.372 0.000
R47.1 Dysarthria and anarthria
0.627 0.373 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.627 0.373 0.000
K91.4 Colostomy and enterostomy malfunction
0.626 0.374 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.625 0.375 0.000
T23.2 Burn of second degree of wrist and hand
0.625 0.375 0.000
I95.0 Idiopathic hypotension
0.625 0.375 0.000
S02.0 Fracture of vault of skull
0.625 0.375 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.625 0.375 0.000
T91.1 Sequelae of fracture of spine
0.624 0.376 0.000
S69 Other and unspecified injuries of wrist and hand
0.624 0.376 0.000
R63.3 Feeding difficulties and mismanagement
0.624 0.376 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.623 0.377 0.000
J98 Other respiratory disorders
0.623 0.377 0.000
I85.0 Oesophageal varices with bleeding
0.622 0.378 0.000
S92 Fracture of foot, except ankle
0.622 0.378 0.000
M86.6 Other chronic osteomyelitis
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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