TreeWAS – Variant ID: rs7816613

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.929	0.071
T43.2 Other and unspecified antidepressants	0.000	0.931	0.069
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.931	0.069
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.933	0.067
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.935	0.065
T39.0 Salicylates	0.000	0.937	0.063
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.938	0.062
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.941	0.059
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.943	0.057
T39.1 4-Aminophenol derivatives	0.000	0.943	0.057
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.945	0.055
T42.4 Benzodiazepines	0.000	0.947	0.053
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.948	0.052
T43.9 Psychotropic drug, unspecified	0.000	0.949	0.051
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.949	0.051
T43.6 Psychostimulants with abuse potential	0.000	0.949	0.051
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.949	0.051
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.949	0.051
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.952	0.048
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.952	0.048
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.952	0.048
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.952	0.048
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.952	0.047
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.953	0.047
T36 Poisoning by systemic antibiotics	0.000	0.953	0.047
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.953	0.046
T39.4 Antirheumatics, not elsewhere classified	0.000	0.953	0.046
T39.2 Pyrazolone derivatives	0.000	0.953	0.046
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.955	0.045
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.955	0.045
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.955	0.045
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.955	0.045
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.955	0.045
T42.3 Barbiturates	0.000	0.955	0.045
T42.2 Succinimides and oxazolidinediones	0.000	0.955	0.045
T42.1 Iminostilbenes	0.000	0.955	0.045
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.956	0.044
T42.0 Hydantoin derivatives	0.000	0.956	0.044
T46.1 Calcium-channel blockers	0.000	0.957	0.043
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.957	0.043
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.958	0.042
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.958	0.042
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.958	0.042
T46.7 Peripheral vasodilators	0.000	0.958	0.042
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.958	0.042
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.958	0.042
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.958	0.042
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.958	0.042
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.958	0.042
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.959	0.041
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.959	0.041
D50.8 Other iron deficiency anaemias	0.037	0.963	0.000
T40.4 Other synthetic narcotics	0.000	0.965	0.035
T41.5 Therapeutic gases	0.000	0.965	0.035
T41.4 Anaesthetic, unspecified	0.000	0.965	0.035
T41.3 Local anaesthetics	0.000	0.965	0.035
T41.2 Other and unspecified general anaesthetics	0.000	0.965	0.035
T41.1 Intravenous anaesthetics	0.000	0.965	0.035
T41.0 Inhaled anaesthetics	0.000	0.965	0.035
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.965	0.035
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.965	0.035
T48.5 Anti-common-cold drugs	0.000	0.965	0.035
T48.4 Expectorants	0.000	0.965	0.035
T48.3 Antitussives	0.000	0.965	0.035
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.965	0.035
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.965	0.035
T48.0 Oxytocic drugs	0.000	0.965	0.035
T49.9 Topical agent, unspecified	0.000	0.965	0.035
T49.8 Other topical agents	0.000	0.965	0.035
T49.7 Dental drugs, topically applied	0.000	0.965	0.035
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.965	0.035
T49.5 Ophthalmological drugs and preparations	0.000	0.965	0.035
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.965	0.035
T49.3 Emollients, demulcents and protectants	0.000	0.965	0.035
T49.2 Local astringents and local detergents	0.000	0.965	0.035
T49.1 Antipruritics	0.000	0.965	0.035
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.965	0.035
T50.8 Diagnostic agents	0.000	0.965	0.035
T50.7 Analeptics and opioid receptor antagonists	0.000	0.965	0.035
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.965	0.035
T50.5 Appetite depressants	0.000	0.965	0.035
T50.4 Drugs affecting uric acid metabolism	0.000	0.965	0.035
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.965	0.035
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.965	0.035
T50.1 Loop [high-ceiling] diuretics	0.000	0.965	0.035
T50.0 Mineralocorticoids and their antagonists	0.000	0.965	0.035
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.965	0.035
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.966	0.034
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.966	0.034
T47.7 Emetics	0.000	0.966	0.034
T47.6 Antidiarrhoeal drugs	0.000	0.966	0.034
T47.5 Digestants	0.000	0.966	0.034
T47.4 Other laxatives	0.000	0.966	0.034
T47.3 Saline and osmotic laxatives	0.000	0.966	0.034
T47.2 Stimulant laxatives	0.000	0.966	0.034
T47.0 Histamine H(2)-receptor antagonists	0.000	0.966	0.034
T38.9 Other and unspecified hormone antagonists	0.000	0.966	0.034
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.966	0.034
T38.7 Androgens and anabolic congeners	0.000	0.966	0.034
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.966	0.034
T38.5 Other oestrogens and progestogens	0.000	0.966	0.034
T38.4 Oral contraceptives	0.000	0.966	0.034
T38.2 Antithyroid drugs	0.000	0.966	0.034
T38.1 Thyroid hormones and substitutes	0.000	0.966	0.034
T38.0 Glucocorticoids and synthetic analogues	0.000	0.966	0.034
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.966	0.034
T36.9 Systemic antibiotic, unspecified	0.000	0.966	0.034
T36.8 Other systemic antibiotics	0.000	0.966	0.034
T36.7 Antifungal antibiotics, systemically used	0.000	0.966	0.034
T36.6 Rifamycins	0.000	0.966	0.034
T36.5 Aminoglycosides	0.000	0.966	0.034
T36.4 Tetracyclines	0.000	0.966	0.034
T36.3 Macrolides	0.000	0.966	0.034
T36.2 Chloramphenicol group	0.000	0.966	0.034
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.966	0.034
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.966	0.033
T45.5 Anticoagulants	0.000	0.967	0.033
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.968	0.032
T45.8 Other primarily systemic and haematological agents	0.000	0.968	0.032
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.968	0.032
T45.6 Fibrinolysis-affecting drugs	0.000	0.968	0.032
T45.4 Iron and its compounds	0.000	0.968	0.032
T45.3 Enzymes, not elsewhere classified	0.000	0.968	0.032
T45.2 Vitamins, not elsewhere classified	0.000	0.968	0.032
T36.0 Penicillins	0.000	0.968	0.032
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.968	0.032
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.968	0.032
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.968	0.032
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.968	0.032
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.968	0.032
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.968	0.032
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.968	0.032
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.968	0.032
T44.0 Anticholinesterase agents	0.000	0.968	0.032
T45.0 Antiallergic and antiemetic drugs	0.000	0.968	0.032
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.969	0.031
T37.5 Antiviral drugs	0.000	0.969	0.031
T37.4 Anthelminthics	0.000	0.969	0.031
T37.3 Other antiprotozoal drugs	0.000	0.969	0.031
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.969	0.031
T37.1 Antimycobacterial drugs	0.000	0.969	0.031
T37.0 Sulphonamides	0.000	0.969	0.031
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.969	0.031
T40.8 Lysergide [LSD]	0.000	0.969	0.031
T40.7 Cannabis (derivatives)	0.000	0.969	0.031
T40.5 Cocaine	0.000	0.969	0.031
T40.3 Methadone	0.000	0.969	0.031
T40.1 Heroin	0.000	0.969	0.031
T40.0 Opium	0.000	0.969	0.031
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.971	0.028
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.972	0.028
N81.4 Uterovaginal prolapse, unspecified	0.028	0.972	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.974	0.025
T40.2 Other opioids	0.000	0.974	0.025
T40.6 Other and unspecified narcotics	0.000	0.976	0.023
N81.6 Rectocele	0.020	0.980	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.980	0.020
N81 Female genital prolapse	0.015	0.985	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.986	0.014
I60.9 Subarachnoid haemorrhage, unspecified	0.012	0.988	0.000
I60 Subarachnoid haemorrhage	0.012	0.988	0.000
Z93.2 Ileostomy status	0.011	0.989	0.000
I31 Other diseases of pericardium	0.000	0.989	0.011
N81.1 Cystocele	0.011	0.989	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.990	0.010
N81.0 Female urethrocele	0.010	0.990	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.010	0.990	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.990	0.010
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.010	0.990	0.000
I60.8 Other subarachnoid haemorrhage	0.010	0.990	0.000
N81.8 Other female genital prolapse	0.010	0.990	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.010	0.990	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.010	0.990	0.000
N81.5 Vaginal enterocele	0.010	0.990	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.009	0.990	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.009	0.991	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.991	0.009
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.009	0.991	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.008	0.991	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.008	0.991	0.000
I31.8 Other specified diseases of pericardium	0.000	0.992	0.008
I31.2 Haemopericardium, not elsewhere classified	0.000	0.992	0.008
I31.1 Chronic constrictive pericarditis	0.000	0.992	0.008
I31.0 Chronic adhesive pericarditis	0.000	0.992	0.008
N81.9 Female genital prolapse, unspecified	0.008	0.992	0.000
N81.3 Complete uterovaginal prolapse	0.008	0.992	0.000
T51.0 Ethanol	0.000	0.992	0.008
C34.3 Lower lobe, bronchus or lung	0.000	0.992	0.007
C34.2 Middle lobe, bronchus or lung	0.000	0.993	0.007
Z91.5 Personal history of self-harm	0.000	0.993	0.007
C34.0 Main bronchus	0.000	0.993	0.007
C34.8 Overlapping lesion of bronchus and lung	0.000	0.993	0.006
Q65.8 Other congenital deformities of hip	0.006	0.994	0.000
I12.0 Hypertensive renal disease with renal failure	0.006	0.994	0.000
T51 Toxic effect of alcohol	0.000	0.995	0.005
D50 Iron deficiency anaemia	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
J02 Acute pharyngitis	0.000	0.995	0.005
N81.2 Incomplete uterovaginal prolapse	0.005	0.995	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.005	0.995	0.000
E22.1 Hyperprolactinaemia	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
Y85.0 Sequelae of motor-vehicle accident	0.004	0.996	0.000
I12 Hypertensive renal disease	0.004	0.996	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.004	0.996	0.000
T51.8 Other alcohols	0.000	0.996	0.004
T51.3 Fusel oil	0.000	0.996	0.004
T51.2 2-Propanol	0.000	0.996	0.004
T51.1 Methanol	0.000	0.996	0.004
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
I12.9 Hypertensive renal disease without renal failure	0.004	0.996	0.000
T51.9 Alcohol, unspecified	0.000	0.996	0.004
D50.1 Sideropenic dysphagia	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.004	0.996	0.000
Q65.6 Unstable hip	0.004	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.004	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.004	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.004	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.004	0.996	0.000
C32 Malignant neoplasm of larynx	0.000	0.996	0.004
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.996	0.004
J02.0 Streptococcal pharyngitis	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
C32.9 Larynx, unspecified	0.000	0.996	0.004
C34.1 Upper lobe, bronchus or lung	0.000	0.996	0.004
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
E10.3 With ophthalmic complications	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
E10.9 Without complications	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
T63.4 Venom of other arthropods	0.000	0.997	0.003
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
C32.1 Supraglottis	0.000	0.997	0.003
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q07.0 Arnold-Chiari syndrome	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
T63 Toxic effect of contact with venomous animals	0.000	0.997	0.003
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
Q82.5 Congenital nonneoplastic naevus	0.003	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.997	0.003
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.997	0.003
C31 Malignant neoplasm of accessory sinuses	0.000	0.997	0.003
C33 Malignant neoplasm of trachea	0.000	0.997	0.003
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.997	0.003
E10.1 With ketoacidosis	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.003	0.997	0.000
C32.8 Overlapping lesion of larynx	0.000	0.997	0.003
C32.3 Laryngeal cartilage	0.000	0.997	0.003
C32.2 Subglottis	0.000	0.997	0.003
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
C37 Malignant neoplasm of thymus	0.000	0.997	0.003
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.000	0.997	0.003
E10.7 With multiple complications	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q82.9 Congenital malformation of skin, unspecified	0.003	0.997	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.003	0.997	0.000
Q82.3 Incontinentia pigmenti	0.003	0.997	0.000
Q82.2 Mastocytosis	0.003	0.997	0.000
Q82.1 Xeroderma pigmentosum	0.003	0.997	0.000
Q82.0 Hereditary lymphoedema	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.997	0.000
Q68.3 Congenital bowing of femur	0.002	0.997	0.000
Q68.2 Congenital deformity of knee	0.002	0.997	0.000
Q68.1 Congenital deformity of hand	0.002	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.997	0.000
Q69.9 Polydactyly, unspecified	0.002	0.997	0.000
Q69.2 Accessory toe(s)	0.002	0.997	0.000
Q69.1 Accessory thumb(s)	0.002	0.997	0.000
Q69.0 Accessory finger(s)	0.002	0.997	0.000
Q70.9 Syndactyly, unspecified	0.002	0.997	0.000
Q70.4 Polysyndactyly	0.002	0.997	0.000
Q70.3 Webbed toes	0.002	0.997	0.000
Q70.2 Fused toes	0.002	0.997	0.000
Q70.1 Webbed fingers	0.002	0.997	0.000
Q70.0 Fused fingers	0.002	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.997	0.000
Q71.6 Lobster-claw hand	0.002	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.997	0.000
Q72.7 Split foot	0.002	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.997	0.000
Q75.3 Macrocephaly	0.002	0.997	0.000
Q75.2 Hypertelorism	0.002	0.997	0.000
Q75.1 Craniofacial dysostosis	0.002	0.997	0.000
Q75.0 Craniosynostosis	0.002	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.997	0.000
Q77.5 Diastrophic dysplasia	0.002	0.997	0.000
Q77.4 Achondroplasia	0.002	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.997	0.000
Q77.2 Short rib syndrome	0.002	0.997	0.000
Q77.1 Thanatophoric short stature	0.002	0.997	0.000
Q77.0 Achondrogenesis	0.002	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.997	0.000
Q78.6 Multiple congenital exostoses	0.002	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.997	0.000
Q78.4 Enchondromatosis	0.002	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.997	0.000
Q78.2 Osteopetrosis	0.002	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
T58 Toxic effect of carbon monoxide	0.000	0.997	0.003
Q12 Congenital lens malformations	0.003	0.997	0.000
T56 Toxic effect of metals	0.000	0.997	0.003
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.997	0.003
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q04 Other congenital malformations of brain	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.000	0.997	0.002
T63.8 Toxic effect of contact with other venomous animals	0.000	0.997	0.002
T63.6 Toxic effect of contact with other marine animals	0.000	0.997	0.002
T63.5 Toxic effect of contact with fish	0.000	0.997	0.002
T63.3 Venom of spider	0.000	0.997	0.002
T63.2 Venom of scorpion	0.000	0.997	0.002
T63.1 Venom of other reptiles	0.000	0.997	0.002
T63.0 Snake venom	0.000	0.997	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
C31.9 Accessory sinus, unspecified	0.000	0.997	0.002
C31.8 Overlapping lesion of accessory sinuses	0.000	0.997	0.002
C31.3 Sphenoidal sinus	0.000	0.997	0.002
C31.2 Frontal sinus	0.000	0.997	0.002
C31.1 Ethmoidal sinus	0.000	0.997	0.002
C31.0 Maxillary sinus	0.000	0.997	0.002
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.997	0.002
C38.4 Pleura	0.000	0.997	0.002
C38.3 Mediastinum, part unspecified	0.000	0.997	0.002
C38.2 Posterior mediastinum	0.000	0.997	0.002
C38.1 Anterior mediastinum	0.000	0.997	0.002
C38.0 Heart	0.000	0.997	0.002
C39.9 Ill-defined sites within the respiratory system	0.000	0.997	0.002
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.997	0.002
C39.0 Upper respiratory tract, part unspecified	0.000	0.997	0.002
E24 Cushing's syndrome	0.003	0.997	0.000
T65 Toxic effect of other and unspecified substances	0.000	0.997	0.002
T62 Toxic effect of other noxious substances eaten as food	0.000	0.997	0.002
T61 Toxic effect of noxious substances eaten as seafood	0.000	0.997	0.002
T60 Toxic effect of pesticides	0.000	0.997	0.002
T57 Toxic effect of other inorganic substances	0.000	0.997	0.002
T54 Toxic effect of corrosive substances	0.000	0.997	0.002
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.997	0.002
T52 Toxic effect of organic solvents	0.000	0.997	0.002
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.997	0.002
T55 Toxic effect of soaps and detergents	0.000	0.997	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.003	0.997	0.000
I05.0 Mitral stenosis	0.000	0.997	0.003
K50.8 Other Crohn's disease	0.000	0.997	0.003
Q17 Other congenital malformations of ear	0.002	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
Q25 Congenital malformations of great arteries	0.002	0.997	0.000
N94.6 Dysmenorrhoea, unspecified	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.997	0.000
Q15 Other congenital malformations of eye	0.002	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations