TreeWAS – Variant ID: rs7823724

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter X Diseases of the respiratory system	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.988	0.012
Chapter XII Diseases of the skin and subcutaneous tissue	0.984	0.016
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.982	0.018
E70-E90 Metabolic disorders	0.978	0.022
Chapter VIII Diseases of the ear and mastoid process	0.974	0.026
L80-L99 Other disorders of the skin and subcutaneous tissue	0.970	0.030
Chapter I Certain infectious and parasitic diseases	0.969	0.031
J30-J39 Other diseases of upper respiratory tract	0.964	0.036
M45-M49 Spondylopathies	0.963	0.037
E87 Other disorders of fluid, electrolyte and acid-base balance	0.957	0.043
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.956	0.044
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.945	0.055
Chapter VI Diseases of the nervous system	0.939	0.061
M47 Spondylosis	0.935	0.065
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.935	0.065
E86 Volume depletion	0.931	0.069
H65-H75 Diseases of middle ear and mastoid	0.927	0.073
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.924	0.076
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.921	0.079
B95-B98 Bacterial, viral and other infectious agents	0.918	0.082
G40-G47 Episodic and paroxysmal disorders	0.917	0.083
M05-M14 Inflammatory polyarthropathies	0.900	0.100
Chapter V Mental and behavioural disorders	0.897	0.103
R42 Dizziness and giddiness	0.897	0.103
Chapter XX External causes of morbidity and mortality	0.890	0.110
T36-T50 Poisoning by drugs, medicaments and biological substances	0.888	0.112
J80-J84 Other respiratory diseases principally affecting the interstitium	0.888	0.112
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.884	0.116
M47.8 Other spondylosis	0.879	0.121
J35 Chronic diseases of tonsils and adenoids	0.868	0.132
J40-J47 Chronic lower respiratory diseases	0.863	0.137
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.862	0.138
J32 Chronic sinusitis	0.859	0.141
G43 Migraine	0.858	0.142
M13 Other arthritis	0.857	0.143
E87.1 Hypo-osmolality and hyponatraemia	0.855	0.145
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.852	0.148
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.849	0.151
E87.2 Acidosis	0.847	0.153
M47.9 Spondylosis, unspecified	0.843	0.157
E00-E07 Disorders of thyroid gland	0.840	0.160
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.839	0.161
M13.9 Arthritis, unspecified	0.827	0.173
Chapter XXII Codes for special purposes	0.825	0.175
S00-S09 Injuries to the head	0.825	0.175
M48 Other spondylopathies	0.824	0.176
A30-A49 Other bacterial diseases	0.822	0.178
H72 Perforation of tympanic membrane	0.819	0.181
M80-M85 Disorders of bone density and structure	0.817	0.183
G43.9 Migraine, unspecified	0.816	0.184
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.814	0.186
L97 Ulcer of lower limb, not elsewhere classified	0.814	0.186
J33 Nasal polyp	0.810	0.190
J95-J99 Other diseases of the respiratory system	0.810	0.190
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.810	0.190
E65-E68 Obesity and other hyperalimentation	0.810	0.190
J32.9 Chronic sinusitis, unspecified	0.808	0.192
G47 Sleep disorders	0.797	0.203
Y43 Primarily systemic agents	0.797	0.203
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.797	0.203
H66 Suppurative and unspecified otitis media	0.794	0.206
E87.5 Hyperkalaemia	0.791	0.209
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.790	0.210
H90-H95 Other disorders of ear	0.787	0.213
H80-H83 Diseases of inner ear	0.786	0.214
R91 Abnormal findings on diagnostic imaging of lung	0.786	0.214
E87.6 Hypokalaemia	0.785	0.215
E20-E35 Disorders of other endocrine glands	0.785	0.215
G45 Transient cerebral ischaemic attacks and related syndromes	0.784	0.216
M13.99 Arthritis, unspecified (Site unspecified)	0.782	0.218
M47.80 Other spondylosis (Multiple sites in spine)	0.781	0.219
B35-B49 Mycoses	0.779	0.221
J60-J70 Lung diseases due to external agents	0.772	0.228
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.771	0.229
L85 Other epidermal thickening	0.770	0.230
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.764	0.236
E04 Other non-toxic goitre	0.763	0.236
L81 Other disorders of pigmentation	0.762	0.238
J81 Pulmonary oedema	0.762	0.238
J00-J06 Acute upper respiratory infections	0.762	0.238
Y43.3 Other antineoplastic drugs	0.760	0.240
F40-F48 Neurotic, stress-related and somatoform disorders	0.759	0.241
L57 Skin changes due to chronic exposure to nonionising radiation	0.757	0.243
Chapter IX Diseases of the circulatory system	0.756	0.244
H70 Mastoiditis and related conditions	0.755	0.245
F60-F69 Disorders of adult personality and behaviour	0.754	0.246
L20-L30 Dermatitis and eczema	0.752	0.248
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.750	0.250
Chapter II Neoplasms	0.750	0.250
S90-S99 Injuries to the ankle and foot	0.745	0.255
E83 Disorders of mineral metabolism	0.745	0.255
J35.0 Chronic tonsillitis	0.743	0.257
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.741	0.259
S01 Open wound of head	0.741	0.259
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.740	0.260
L89 Decubitus ulcer	0.739	0.260
M86-M90 Other osteopathies	0.739	0.261
H65 Nonsuppurative otitis media	0.739	0.261
F30-F39 Mood [affective] disorders	0.739	0.261
M47.82 Other spondylosis (Cervical region)	0.736	0.264
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.736	0.264
L91 Hypertrophic disorders of skin	0.735	0.265
J84 Other interstitial pulmonary diseases	0.733	0.267
A00-A09 Intestinal infectious diseases	0.733	0.267
L90 Atrophic disorders of skin	0.731	0.268
H60-H62 Diseases of external ear	0.730	0.269
G47.3 Sleep apnoea	0.730	0.270
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.730	0.270
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.723	0.277
S80-S89 Injuries to the knee and lower leg	0.722	0.278
J09-J18 Influenza and pneumonia	0.722	0.278
J47 Bronchiectasis	0.720	0.280
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283
H72.9 Perforation of tympanic membrane, unspecified	0.716	0.284
M47.86 Other spondylosis (Lumbar region)	0.715	0.285
T66-T78 Other and unspecified effects of external causes	0.715	0.285
A50-A64 Infections with a predominantly sexual mode of transmission	0.715	0.285
M40-M43 Deforming dorsopathies	0.714	0.286
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.714	0.286
S50-S59 Injuries to the elbow and forearm	0.712	0.288
M15-M19 Arthrosis	0.711	0.289
E88 Other metabolic disorders	0.711	0.289
X40-X49 Accidental poisoning by and exposure to noxious substances	0.710	0.290
M47.92 Spondylosis, unspecified (Cervical region)	0.709	0.291
E40-E46 Malnutrition	0.709	0.291
F99-F99 Unspecified mental disorder	0.708	0.292
B15-B19 Viral hepatitis	0.708	0.292
R94 Abnormal results of function studies	0.707	0.293
G35-G37 Demyelinating diseases of the central nervous system	0.706	0.293
L10-L14 Bullous disorders	0.705	0.294
G90-G99 Other disorders of the nervous system	0.704	0.295
M91-M94 Chondropathies	0.704	0.296
M60-M63 Disorders of muscles	0.704	0.296
M00-M03 Infectious arthropathies	0.704	0.296
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.704	0.296
A41 Other septicaemia	0.703	0.297
E87.7 Fluid overload	0.703	0.297
L50-L54 Urticaria and erythema	0.702	0.298
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.701	0.299
E85 Amyloidosis	0.701	0.299
E84 Cystic fibrosis	0.701	0.299
E80 Disorders of porphyrin and bilirubin metabolism	0.701	0.299
E79 Disorders of purine and pyrimidine metabolism	0.701	0.299
E77 Disorders of glycoprotein metabolism	0.701	0.299
E76 Disorders of glycosaminoglycan metabolism	0.701	0.299
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.701	0.299
E74 Other disorders of carbohydrate metabolism	0.701	0.299
E73 Lactose intolerance	0.701	0.299
E72 Other disorders of amino-acid metabolism	0.701	0.299
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.701	0.299
E70 Disorders of aromatic amino-acid metabolism	0.701	0.299
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.701	0.299
T79-T79 Certain early complications of trauma	0.700	0.300
M81 Osteoporosis without pathological fracture	0.699	0.301
J40 Bronchitis, not specified as acute or chronic	0.699	0.301
H66.9 Otitis media, unspecified	0.698	0.302
R93 Abnormal findings on diagnostic imaging of other body structures	0.698	0.302
R47-R49 Symptoms and signs involving speech and voice	0.698	0.302
R44 Other symptoms and signs involving general sensations and perceptions	0.696	0.304
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.696	0.304
L95 Vasculitis limited to skin, not elsewhere classified	0.696	0.304
L94 Other localised connective tissue disorders	0.696	0.304
L93 Lupus erythematosus	0.696	0.304
L92 Granulomatous disorders of skin and subcutaneous tissue	0.696	0.304
L87 Transepidermal elimination disorders	0.696	0.304
L88 Pyoderma gangrenosum	0.696	0.304
L86 Keratoderma in diseases classified elsewhere	0.696	0.304
L84 Corns and callosities	0.696	0.304
L83 Acanthosis nigricans	0.696	0.304
L80 Vitiligo	0.696	0.304
R40 Somnolence, stupor and coma	0.696	0.304
L00-L08 Infections of the skin and subcutaneous tissue	0.695	0.305
B99-B99 Other infectious diseases	0.695	0.305
B90-B94 Sequelae of infectious and parasitic diseases	0.695	0.305
B85-B89 Pediculosis, acariasis and other infestations	0.695	0.305
B65-B83 Helminthiases	0.695	0.305
B50-B64 Protozoal diseases	0.695	0.305
B20-B24 Human immunodeficiency virus [HIV] disease	0.695	0.305
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.695	0.305
A80-A89 Viral infections of the central nervous system	0.695	0.305
A75-A79 Rickettsioses	0.695	0.305
A70-A74 Other diseases caused by chlamydiae	0.695	0.305
A65-A69 Other spirochaetal diseases	0.695	0.305
A20-A28 Certain zoonotic bacterial diseases	0.695	0.305
A15-A19 Tuberculosis	0.695	0.305
J35.8 Other chronic diseases of tonsils and adenoids	0.692	0.308
J37 Chronic laryngitis and laryngotracheitis	0.691	0.309
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.691	0.309
M49 Spondylopathies in diseases classified elsewhere	0.690	0.310
M46 Other inflammatory spondylopathies	0.690	0.310
M45 Ankylosing spondylitis	0.690	0.310
L57.0 Actinic keratosis	0.689	0.311
I30-I52 Other forms of heart disease	0.689	0.311
T39.1 4-Aminophenol derivatives	0.689	0.311
R21 Rash and other nonspecific skin eruption	0.688	0.311
J39 Other diseases of upper respiratory tract	0.688	0.312
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.687	0.313
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.686	0.314
E87.4 Mixed disorder of acid-base balance	0.686	0.314
E87.3 Alkalosis	0.686	0.314
E87.0 Hyperosmolality and hypernatraemia	0.686	0.314
T33-T35 Frostbite	0.685	0.315
T26-T28 Burns and corrosions confined to eye and internal organs	0.685	0.315
T20-T25 Burns and corrosions of external body surface, specified by site	0.685	0.315
T15-T19 Effects of foreign body entering through natural orifice	0.685	0.315
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.685	0.315
T00-T07 Injuries involving multiple body regions	0.685	0.315
S10-S19 Injuries to the neck	0.685	0.315
E50-E64 Other nutritional deficiencies	0.684	0.316
J20-J22 Other acute lower respiratory infections	0.684	0.316
E66 Obesity	0.682	0.318
G30-G32 Other degenerative diseases of the nervous system	0.681	0.319
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.681	0.319
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.681	0.319
S70-S79 Injuries to the hip and thigh	0.681	0.319
M48.0 Spinal stenosis	0.681	0.319
M47.96 Spondylosis, unspecified (Lumbar region)	0.679	0.321
J35.1 Hypertrophy of tonsils	0.678	0.321
R95-R99 Ill-defined and unknown causes of mortality	0.677	0.323
J36 Peritonsillar abscess	0.677	0.323
J44 Other chronic obstructive pulmonary disease	0.677	0.323
Q50-Q56 Congenital malformations of genital organs	0.677	0.323
R90 Abnormal findings on diagnostic imaging of central nervous system	0.676	0.324
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.675	0.325
G70-G73 Diseases of myoneural junction and muscle	0.673	0.327
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.673	0.327
G00-G09 Inflammatory diseases of the central nervous system	0.673	0.327
S60-S69 Injuries to the wrist and hand	0.672	0.328
M47.2 Other spondylosis with radiculopathy	0.671	0.329
M47.1 Other spondylosis with myelopathy	0.671	0.329
M47.0 Anterior spinal and vertebral artery compression syndromes	0.671	0.329
R45 Symptoms and signs involving emotional state	0.670	0.329
L98.7 Excessive and redundant skin and subcutaneous tissue	0.670	0.330
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.670	0.330
L98.5 Mucinosis of skin	0.670	0.330
L98.4 Chronic ulcer of skin, not elsewhere classified	0.670	0.330
L98.3 Eosinophilic cellulitis [Wells]	0.670	0.330
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.670	0.330
L98.1 Factitial dermatitis	0.670	0.330
J33.0 Polyp of nasal cavity	0.668	0.332
R41 Other symptoms and signs involving cognitive functions and awareness	0.668	0.332
F41 Other anxiety disorders	0.666	0.334
S20-S29 Injuries to the thorax	0.665	0.335
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.665	0.335
H74 Other disorders of middle ear and mastoid	0.665	0.335
H69 Other disorders of Eustachian tube	0.665	0.335
H68 Eustachian salpingitis and obstruction	0.665	0.335
H67 Otitis media in diseases classified elsewhere	0.665	0.335
S40-S49 Injuries to the shoulder and upper arm	0.664	0.336
M13.94 Arthritis, unspecified (Hand)	0.664	0.336
Y60-Y69 Misadventures to patients during surgical and medical care	0.664	0.336
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.663	0.337
M48.5 Collapsed vertebra, not elsewhere classified	0.663	0.337
F00-F09 Organic, including symptomatic, mental disorders	0.662	0.338
J30 Vasomotor and allergic rhinitis	0.662	0.338
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.661	0.339
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.660	0.339
R46 Symptoms and signs involving appearance and behaviour	0.660	0.340
R43 Disturbances of smell and taste	0.660	0.340
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.660	0.340
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.659	0.341
E05 Thyrotoxicosis [hyperthyroidism]	0.658	0.342
H73 Other disorders of tympanic membrane	0.658	0.342
G46 Vascular syndromes of brain in cerebrovascular diseases	0.657	0.343
G44 Other headache syndromes	0.657	0.343
G41 Status epilepticus	0.657	0.343
Y57 Other and unspecified drugs and medicaments	0.656	0.344
M11 Other crystal arthropathies	0.655	0.345
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.654	0.346
J95 Postprocedural respiratory disorders, not elsewhere classified	0.654	0.346
H92 Otalgia and effusion of ear	0.654	0.346
E04.9 Non-toxic goitre, unspecified	0.654	0.346
J38.3 Other diseases of vocal cords	0.653	0.347
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.653	0.347
F60 Specific personality disorders	0.652	0.348
Q60-Q64 Congenital malformations of the urinary system	0.652	0.348
G45.3 Amaurosis fugax	0.650	0.350
J42 Unspecified chronic bronchitis	0.650	0.350
E28 Ovarian dysfunction	0.648	0.351
M50-M54 Other dorsopathies	0.647	0.353
H72.0 Central perforation of tympanic membrane	0.646	0.354
M14 Arthropathies in other diseases classified elsewhere	0.646	0.354
M12 Other specific arthropathies	0.646	0.354
M09 Juvenile arthritis in diseases classified elsewhere	0.646	0.354
M08 Juvenile arthritis	0.646	0.354
M05 Seropositive rheumatoid arthritis	0.646	0.354
I95-I99 Other and unspecified disorders of the circulatory system	0.646	0.354
S01.1 Open wound of eyelid and periocular area	0.644	0.355
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.644	0.356
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.643	0.357
F80-F89 Disorders of psychological development	0.643	0.357
F70-F79 Mental retardation	0.643	0.357
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.643	0.357
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.643	0.357
B97 Viral agents as the cause of diseases classified to other chapters	0.642	0.358
M07 Psoriatic and enteropathic arthropathies	0.642	0.358
T43.2 Other and unspecified antidepressants	0.642	0.358
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.641	0.359
L98.0 Pyogenic granuloma	0.641	0.359
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.641	0.359
M13.96 Arthritis, unspecified (Lower leg)	0.641	0.359
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.640	0.360
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.638	0.362
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.638	0.362
Y35-Y36 Legal intervention and operations of war	0.638	0.362
Y10-Y34 Event of undetermined intent	0.638	0.362
Y00-Y09 Assault	0.638	0.362
X85-X99 Assault	0.638	0.362
X60-X84 Intentional self-harm	0.638	0.362
X58-X59 Accidental exposure to other and unspecified factors	0.638	0.362
X50-X57 Overexertion, travel and privation	0.638	0.362
X30-X39 Exposure to forces of nature	0.638	0.362
X20-X29 Contact with venomous animals and plants	0.638	0.362
X10-X19 Contact with heat and hot substances	0.638	0.362
X00-X09 Exposure to smoke, fire and flames	0.638	0.362
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.638	0.362
W75-W84 Other accidental threats to breathing	0.638	0.362
W65-W74 Accidental drowning and submersion	0.638	0.362
W50-W64 Exposure to animate mechanical forces	0.638	0.362
W20-W49 Exposure to inanimate mechanical forces	0.638	0.362
V98-V99 Other and unspecified transport accidents	0.638	0.362
V95-V97 Air and space transport accidents	0.638	0.362
V90-V94 Water transport accidents	0.638	0.362
V80-V89 Other land transport accidents	0.638	0.362
V70-V79 Bus occupant injured in transport accident	0.638	0.362
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.638	0.362
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.638	0.362
V40-V49 Car occupant injured in transport accident	0.638	0.362
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.638	0.362
V20-V29 Motorcycle rider injured in transport accident	0.638	0.362
V01-V09 Pedestrian injured in transport accident	0.638	0.362
A41.9 Septicaemia, unspecified	0.637	0.363
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.637	0.363
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.637	0.363
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.637	0.363
T46 Poisoning by agents primarily affecting the cardiovascular system	0.637	0.363
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.637	0.363
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.637	0.363
T41 Poisoning by anaesthetics and therapeutic gases	0.637	0.363
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.637	0.363
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.637	0.363
T36 Poisoning by systemic antibiotics	0.637	0.363
J82 Pulmonary eosinophilia, not elsewhere classified	0.636	0.364
J80 Adult respiratory distress syndrome	0.636	0.364
M13.90 Arthritis, unspecified (Multiple sites)	0.635	0.364
R92 Abnormal findings on diagnostic imaging of breast	0.634	0.366
E04.1 Non-toxic single thyroid nodule	0.634	0.366
J34 Other disorders of nose and nasal sinuses	0.634	0.366
J33.9 Nasal polyp, unspecified	0.633	0.367
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.633	0.367
S00 Superficial injury of head	0.633	0.367
B25-B34 Other viral diseases	0.633	0.367
S06 Intracranial injury	0.633	0.367
B44 Aspergillosis	0.631	0.369
H70.9 Mastoiditis, unspecified	0.631	0.369
L40-L45 Papulosquamous disorders	0.631	0.369
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.630	0.370
M47.89 Other spondylosis (Site unspecified)	0.630	0.370
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.630	0.370
M47.85 Other spondylosis (Thoracolumbar region)	0.630	0.370
M47.84 Other spondylosis (Thoracic region)	0.630	0.370
M47.83 Other spondylosis (Cervicothoracic region)	0.630	0.370
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.630	0.370
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.630	0.370
J90-J94 Other diseases of pleura	0.627	0.373
M65-M68 Disorders of synovium and tendon	0.625	0.375
I05-I09 Chronic rheumatic heart diseases	0.625	0.375
G45.4 Transient global amnesia	0.624	0.376
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.624	0.376
Q20-Q28 Congenital malformations of the circulatory system	0.623	0.377
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.622	0.378
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.622	0.378
J35.2 Hypertrophy of adenoids	0.622	0.378
J84.1 Other interstitial pulmonary diseases with fibrosis	0.622	0.378
M06 Other rheumatoid arthritis	0.621	0.378
I47 Paroxysmal tachycardia	0.621	0.379
G40 Epilepsy	0.619	0.381
J41 Simple and mucopurulent chronic bronchitis	0.619	0.381
J46 Status asthmaticus	0.619	0.381
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.618	0.382
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.618	0.382
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.618	0.382
J32.8 Other chronic sinusitis	0.616	0.384
J32.4 Chronic pansinusitis	0.616	0.384
J32.3 Chronic sphenoidal sinusitis	0.616	0.384
J32.2 Chronic ethmoidal sinusitis	0.616	0.384
J32.1 Chronic frontal sinusitis	0.616	0.384
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.616	0.384
G80-G83 Cerebral palsy and other paralytic syndromes	0.616	0.384
G43.8 Other migraine	0.615	0.385
G43.3 Complicated migraine	0.615	0.385
G43.2 Status migrainosus	0.615	0.385
G43.1 Migraine with aura [classical migraine]	0.615	0.385
G43.0 Migraine without aura [common migraine]	0.615	0.385
S01.5 Open wound of lip and oral cavity	0.615	0.385
J98 Other respiratory disorders	0.615	0.385
M81.9 Osteoporosis, unspecified	0.615	0.385
M13.8 Other specified arthritis	0.615	0.385
M13.1 Monoarthritis, not elsewhere classified	0.615	0.385
M13.0 Polyarthritis, unspecified	0.615	0.385
A49 Bacterial infection of unspecified site	0.614	0.385
L85.9 Epidermal thickening, unspecified	0.614	0.386
L81.4 Other melanin hyperpigmentation	0.613	0.387
M70-M79 Other soft tissue disorders	0.612	0.388
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.611	0.389
L58 Radiodermatitis	0.611	0.389
L56 Other acute skin changes due to ultraviolet radiation	0.611	0.389
L55 Sunburn	0.611	0.389
J44.9 Chronic obstructive pulmonary disease, unspecified	0.609	0.391
Y59 Other and unspecified vaccines and biological substances	0.609	0.391
Y58 Bacterial vaccines	0.609	0.391
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.609	0.391
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.609	0.391
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.609	0.391
Y53 Agents primarily affecting the gastro-intestinal system	0.609	0.391
Y52 Agents primarily affecting the cardiovascular system	0.609	0.391
Y51 Drugs primarily affecting the autonomic nervous system	0.609	0.391
Y50 Central nervous system stimulants, not elsewhere classified	0.609	0.391
Y49 Psychotropic drugs, not elsewhere classified	0.609	0.391
Y48 Anaesthetics and therapeutic gases	0.609	0.391
Y47 Sedatives, hypnotics and antianxiety drugs	0.609	0.391
Y46 Antiepileptics and anti-Parkinsonism drugs	0.609	0.391
Y44 Agents primarily affecting blood constituents	0.609	0.391
Y41 Other systemic anti-infectives and antiparasitics	0.609	0.391
Y40 Systemic antibiotics	0.609	0.391
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.608	0.392
V10-V19 Pedal cyclist injured in transport accident	0.608	0.392
H81 Disorders of vestibular function	0.608	0.392
R25 Abnormal involuntary movements	0.607	0.393
H83 Other diseases of inner ear	0.607	0.393
M47.87 Other spondylosis (Lumbosacral region)	0.607	0.393
R30-R39 Symptoms and signs involving the urinary system	0.607	0.393
J45 Asthma	0.606	0.394
E07 Other disorders of thyroid	0.606	0.394
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.605	0.395
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.605	0.395
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.605	0.395
M47.94 Spondylosis, unspecified (Thoracic region)	0.605	0.395
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.605	0.395
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.605	0.395
E66.8 Other obesity	0.605	0.395
H65.3 Chronic mucoid otitis media	0.604	0.396
J00 Acute nasopharyngitis [common cold]	0.604	0.396
E06 Thyroiditis	0.603	0.397
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.603	0.397
E00 Congenital iodine-deficiency syndrome	0.603	0.397
E02 Subclinical iodine-deficiency hypothyroidism	0.603	0.397
M19 Other arthrosis	0.602	0.398
F41.9 Anxiety disorder, unspecified	0.601	0.399
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.601	0.399
Q80-Q89 Other congenital malformations	0.601	0.399
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.601	0.399
Q38-Q45 Other congenital malformations of the digestive system	0.601	0.399
Q35-Q37 Cleft lip and cleft palate	0.601	0.399
Q30-Q34 Congenital malformations of the respiratory system	0.601	0.399
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.601	0.399
Q00-Q07 Congenital malformations of the nervous system	0.601	0.399
H71 Cholesteatoma of middle ear	0.597	0.403
L90.5 Scar conditions and fibrosis of skin	0.593	0.407
M13.98 Arthritis, unspecified (Other)	0.593	0.407
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.593	0.407
M13.93 Arthritis, unspecified (Forearm)	0.593	0.407
M13.92 Arthritis, unspecified (Upper arm)	0.593	0.407
R94.3 Abnormal results of cardiovascular function studies	0.592	0.408
S08 Traumatic amputation of part of head	0.592	0.408
S07 Crushing injury of head	0.592	0.408
S05 Injury of eye and orbit	0.592	0.408
S04 Injury of cranial nerves	0.592	0.408
S03 Dislocation, sprain and strain of joints and ligaments of head	0.592	0.408
I51 Complications and ill-defined descriptions of heart disease	0.591	0.409
M48.9 Spondylopathy, unspecified	0.591	0.409
M48.8 Other specified spondylopathies	0.591	0.409
M48.4 Fatigue fracture of vertebra	0.591	0.409
M48.3 Traumatic spondylopathy	0.591	0.409
M48.2 Kissing spine	0.591	0.409
M48.1 Ankylosing hyperostosis [Forestier]	0.591	0.409
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.590	0.410
A48 Other bacterial diseases, not elsewhere classified	0.589	0.411
A44 Bartonellosis	0.589	0.411
A43 Nocardiosis	0.589	0.411
A42 Actinomycosis	0.589	0.411
A40 Streptococcal septicaemia	0.589	0.411
A39 Meningococcal infection	0.589	0.411
A37 Whooping cough	0.589	0.411
A36 Diphtheria	0.589	0.411
A32 Listeriosis	0.589	0.411
A31 Infection due to other mycobacteria	0.589	0.411
A30 Leprosy [Hansen's disease]	0.589	0.411
A46 Erysipelas	0.589	0.411
A38 Scarlet fever	0.589	0.411
A35 Other tetanus	0.589	0.411
A34 Obstetrical tetanus	0.589	0.411
A33 Tetanus neonatorum	0.589	0.411
F32 Depressive episode	0.588	0.412
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.588	0.412
H72.8 Other perforations of tympanic membrane	0.587	0.412
H72.2 Other marginal perforations of tympanic membrane	0.587	0.412

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations