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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78395048
log Bayes Factor = 13.3551
Chromosome 18   position 50,372,363  (GRCh37) Explore rs78395048 on Ensembl!
Variant rs78395048 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
F30-F39 Mood [affective] disorders
0.992 0.008 0.000
J40-J47 Chronic lower respiratory diseases
0.990 0.010 0.000
Chapter II Neoplasms
0.990 0.010 0.000
M50-M54 Other dorsopathies
0.989 0.011 0.000
M20-M25 Other joint disorders
0.989 0.011 0.000
J44 Other chronic obstructive pulmonary disease
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.981 0.019 0.000
F32 Depressive episode
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.978 0.022 0.000
N10-N16 Renal tubulo-interstitial diseases
0.978 0.022 0.000
M54 Dorsalgia
0.976 0.024 0.000
F32.9 Depressive episode, unspecified
0.973 0.027 0.000
D50-D53 Nutritional anaemias
0.963 0.037 0.000
D60-D64 Aplastic and other anaemias
0.954 0.046 0.000
M54.5 Low back pain
0.949 0.051 0.000
N13 Obstructive and reflux uropathy
0.947 0.053 0.000
M20 Acquired deformities of fingers and toes
0.943 0.057 0.000
M45-M49 Spondylopathies
0.943 0.057 0.000
D50 Iron deficiency anaemia
0.942 0.058 0.000
N00-N08 Glomerular diseases
0.938 0.062 0.000
Chapter IX Diseases of the circulatory system
0.936 0.064 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.936 0.064 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.935 0.065 0.000
Chapter VIII Diseases of the ear and mastoid process
0.935 0.065 0.000
D64 Other anaemias
0.934 0.066 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.932 0.068 0.000
I60-I69 Cerebrovascular diseases
0.931 0.069 0.000
J30-J39 Other diseases of upper respiratory tract
0.928 0.072 0.000
N17-N19 Renal failure
0.927 0.073 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.925 0.075 0.000
D64.9 Anaemia, unspecified
0.919 0.081 0.000
D50.9 Iron deficiency anaemia, unspecified
0.915 0.085 0.000
Chapter VI Diseases of the nervous system
0.915 0.085 0.000
M25 Other joint disorders, not elsewhere classified
0.914 0.086 0.000
I67 Other cerebrovascular diseases
0.910 0.090 0.000
N03 Chronic nephritic syndrome
0.906 0.094 0.000
B95-B98 Bacterial, viral and other infectious agents
0.899 0.101 0.000
J45 Asthma
0.898 0.102 0.000
I10-I15 Hypertensive diseases
0.894 0.106 0.000
N18 Chronic renal failure
0.893 0.107 0.000
M54.59 Low back pain (Site unspecified)
0.893 0.107 0.000
Chapter XXII Codes for special purposes
0.893 0.107 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.893 0.107 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.891 0.109 0.000
I67.8 Other specified cerebrovascular diseases
0.889 0.111 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.888 0.112 0.000
N03.9 Unspecified
0.883 0.117 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.882 0.118 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.876 0.124 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.876 0.124 0.000
A00-A09 Intestinal infectious diseases
0.875 0.125 0.000
Chapter XX External causes of morbidity and mortality
0.870 0.130 0.000
M51 Other intervertebral disk disorders
0.870 0.130 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.870 0.130 0.000
I10 Essential (primary) hypertension
0.865 0.135 0.000
L82 Seborrhoeic keratosis
0.862 0.138 0.000
M20.2 Hallux rigidus
0.855 0.145 0.000
M20.1 Hallux valgus (acquired)
0.854 0.146 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.851 0.149 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.848 0.152 0.000
I69 Sequelae of cerebrovascular disease
0.847 0.153 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.847 0.153 0.000
J45.9 Asthma, unspecified
0.845 0.155 0.000
L60-L75 Disorders of skin appendages
0.843 0.157 0.000
F31 Bipolar affective disorder
0.841 0.159 0.000
M23 Internal derangement of knee
0.840 0.160 0.000
M54.3 Sciatica
0.836 0.164 0.000
H65-H75 Diseases of middle ear and mastoid
0.836 0.164 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.833 0.167 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.830 0.170 0.000
A80-A89 Viral infections of the central nervous system
0.829 0.171 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.827 0.173 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.826 0.174 0.000
M05-M14 Inflammatory polyarthropathies
0.826 0.174 0.000
N10 Acute tubulo-interstitial nephritis
0.819 0.181 0.000
S40-S49 Injuries to the shoulder and upper arm
0.819 0.181 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.818 0.182 0.000
C44 Other malignant neoplasms of skin
0.818 0.182 0.000
D46 Myelodysplastic syndromes
0.817 0.183 0.000
H90-H95 Other disorders of ear
0.816 0.184 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.813 0.187 0.000
M80-M85 Disorders of bone density and structure
0.812 0.188 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.809 0.191 0.000
M48 Other spondylopathies
0.806 0.194 0.000
J33 Nasal polyp
0.806 0.194 0.000
L50-L54 Urticaria and erythema
0.803 0.197 0.000
S20-S29 Injuries to the thorax
0.802 0.198 0.000
N13.3 Other and unspecified hydronephrosis
0.802 0.198 0.000
D50.8 Other iron deficiency anaemias
0.802 0.198 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.801 0.199 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.801 0.199 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.801 0.199 0.000
A30-A49 Other bacterial diseases
0.800 0.200 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.799 0.201 0.000
N18.2 Chronic kidney disease, stage 2
0.797 0.203 0.000
F33 Recurrent depressive disorder
0.796 0.204 0.000
J43 Emphysema
0.796 0.204 0.000
T93 Sequelae of injuries of lower limb
0.796 0.204 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.793 0.207 0.000
M54.2 Cervicalgia
0.792 0.208 0.000
L81 Other disorders of pigmentation
0.789 0.211 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.789 0.211 0.000
M21 Other acquired deformities of limbs
0.788 0.212 0.000
M46 Other inflammatory spondylopathies
0.788 0.212 0.000
H73 Other disorders of tympanic membrane
0.786 0.214 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.786 0.214 0.000
M34 Systemic sclerosis
0.785 0.215 0.000
N18.3 Chronic kidney disease, stage 3
0.784 0.216 0.000
D45 Polycythaemia vera
0.782 0.218 0.000
L40-L45 Papulosquamous disorders
0.781 0.219 0.000
M54.56 Low back pain (Lumbar region)
0.781 0.219 0.000
S50-S59 Injuries to the elbow and forearm
0.781 0.219 0.000
N88 Other noninflammatory disorders of cervix uteri
0.781 0.219 0.000
T66-T78 Other and unspecified effects of external causes
0.779 0.220 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.778 0.222 0.000
M23.8 Other internal derangements of knee
0.775 0.225 0.000
C51-C58 Malignant neoplasms of female genital organs
0.774 0.226 0.000
M47 Spondylosis
0.774 0.226 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.774 0.226 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.772 0.228 0.000
M53 Other dorsopathies, not elsewhere classified
0.772 0.228 0.000
M20.5 Other deformities of toe(s) (acquired)
0.771 0.229 0.000
M91-M94 Chondropathies
0.768 0.232 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.767 0.233 0.000
M25.4 Effusion of joint
0.767 0.233 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.766 0.234 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.766 0.234 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.765 0.235 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.765 0.235 0.000
C44.7 Skin of lower limb, including hip
0.764 0.236 0.000
D10-D36 Benign neoplasms
0.764 0.236 0.000
N97 Female infertility
0.762 0.238 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.760 0.240 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.760 0.240 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.758 0.242 0.000
D80-D89 Certain disorders involving the immune mechanism
0.757 0.242 0.000
N13.8 Other obstructive and reflux uropathy
0.756 0.244 0.000
C44.3 Skin of other and unspecified parts of face
0.755 0.245 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.755 0.245 0.000
M51.2 Other specified intervertebral disk displacement
0.754 0.246 0.000
N81 Female genital prolapse
0.751 0.249 0.000
M86-M90 Other osteopathies
0.751 0.249 0.000
H73.8 Other specified disorders of tympanic membrane
0.751 0.249 0.000
N87 Dysplasia of cervix uteri
0.749 0.251 0.000
S90-S99 Injuries to the ankle and foot
0.749 0.251 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.747 0.253 0.000
B35-B49 Mycoses
0.746 0.254 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.745 0.255 0.000
D17 Benign lipomatous neoplasm
0.743 0.257 0.000
J32 Chronic sinusitis
0.743 0.257 0.000
F10.3 Withdrawal state
0.741 0.259 0.000
J36 Peritonsillar abscess
0.740 0.260 0.000
I05-I09 Chronic rheumatic heart diseases
0.740 0.260 0.000
M25.5 Pain in joint
0.740 0.260 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.738 0.262 0.000
N99-N99 Other disorders of the genitourinary system
0.737 0.263 0.000
M10 Gout
0.737 0.263 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.737 0.263 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.735 0.264 0.000
J33.9 Nasal polyp, unspecified
0.735 0.265 0.000
M54.6 Pain in thoracic spine
0.734 0.266 0.000
N81.6 Rectocele
0.734 0.266 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.732 0.268 0.000
M54.9 Dorsalgia, unspecified
0.732 0.268 0.000
N89 Other noninflammatory disorders of vagina
0.731 0.269 0.000
F60-F69 Disorders of adult personality and behaviour
0.728 0.271 0.000
D52 Folate deficiency anaemia
0.727 0.273 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.727 0.273 0.000
X60-X84 Intentional self-harm
0.727 0.273 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.726 0.274 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.726 0.274 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.724 0.276 0.000
C50-C50 Malignant neoplasm of breast
0.724 0.276 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.724 0.276 0.000
M45 Ankylosing spondylitis
0.724 0.276 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.723 0.277 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.723 0.277 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.722 0.278 0.000
G90-G99 Other disorders of the nervous system
0.721 0.279 0.000
F10.4 Withdrawal state with delirium
0.721 0.279 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.720 0.280 0.000
F31.9 Bipolar affective disorder, unspecified
0.719 0.281 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.716 0.284 0.000
F10.2 Dependence syndrome
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.714 0.286 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.714 0.286 0.000
M25.8 Other specified joint disorders
0.713 0.287 0.000
N18.9 Chronic renal failure, unspecified
0.713 0.287 0.000
I67.2 Cerebral atherosclerosis
0.713 0.287 0.000
N40-N51 Diseases of male genital organs
0.712 0.288 0.000
D55-D59 Haemolytic anaemias
0.712 0.288 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.712 0.288 0.000
F38 Other mood [affective] disorders
0.711 0.289 0.000
F34 Persistent mood [affective] disorders
0.711 0.289 0.000
F30 Manic episode
0.711 0.289 0.000
F39 Unspecified mood [affective] disorder
0.711 0.289 0.000
J39 Other diseases of upper respiratory tract
0.711 0.289 0.000
N13.4 Hydroureter
0.710 0.290 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
S80-S89 Injuries to the knee and lower leg
0.710 0.290 0.000
G35 Multiple sclerosis
0.709 0.291 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.709 0.291 0.000
M33 Dermatopolymyositis
0.709 0.291 0.000
M32 Systemic lupus erythematosus
0.709 0.291 0.000
M30 Polyarteritis nodosa and related conditions
0.709 0.291 0.000
M48.0 Spinal stenosis
0.709 0.291 0.000
I60 Subarachnoid haemorrhage
0.709 0.291 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.708 0.292 0.000
M65-M68 Disorders of synovium and tendon
0.708 0.292 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.707 0.293 0.000
H60-H62 Diseases of external ear
0.707 0.293 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
Y52 Agents primarily affecting the cardiovascular system
0.706 0.294 0.000
F10.0 Acute intoxication
0.705 0.295 0.000
L85 Other epidermal thickening
0.705 0.295 0.000
A86 Unspecified viral encephalitis
0.705 0.295 0.000
M31 Other necrotising vasculopathies
0.704 0.296 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.704 0.296 0.000
J47 Bronchiectasis
0.704 0.296 0.000
A04 Other bacterial intestinal infections
0.703 0.296 0.000
L10-L14 Bullous disorders
0.703 0.297 0.000
F32.8 Other depressive episodes
0.702 0.297 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.702 0.297 0.000
F32.0 Mild depressive episode
0.702 0.297 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.702 0.297 0.000
M70-M79 Other soft tissue disorders
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.701 0.299 0.000
N15 Other renal tubulo-interstitial diseases
0.701 0.299 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.701 0.299 0.000
N11 Chronic tubulo-interstitial nephritis
0.701 0.299 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.701 0.299 0.000
N84 Polyp of female genital tract
0.700 0.300 0.000
M24 Other specific joint derangements
0.700 0.300 0.000
M54.8 Other dorsalgia
0.700 0.300 0.000
M54.4 Lumbago with sciatica
0.700 0.300 0.000
M54.0 Panniculitis affecting regions of neck and back
0.700 0.300 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.699 0.301 0.000
W00-W19 Falls
0.698 0.302 0.000
S00-S09 Injuries to the head
0.698 0.302 0.000
F32.1 Moderate depressive episode
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.303 0.000
D61 Other aplastic anaemias
0.696 0.304 0.000
J46 Status asthmaticus
0.694 0.306 0.000
B15-B19 Viral hepatitis
0.693 0.306 0.000
W20-W49 Exposure to inanimate mechanical forces
0.693 0.307 0.000
N30-N39 Other diseases of urinary system
0.692 0.308 0.000
G30-G32 Other degenerative diseases of the nervous system
0.692 0.308 0.000
M40-M43 Deforming dorsopathies
0.691 0.309 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.690 0.310 0.000
D53 Other nutritional anaemias
0.690 0.310 0.000
L89 Decubitus ulcer
0.690 0.310 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.690 0.310 0.000
J95-J99 Other diseases of the respiratory system
0.689 0.311 0.000
C79 Secondary malignant neoplasm of other sites
0.689 0.311 0.000
I69.3 Sequelae of cerebral infarction
0.689 0.311 0.000
C92 Myeloid leukaemia
0.688 0.312 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.688 0.312 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.688 0.312 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.688 0.312 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.687 0.312 0.000
M54.39 Sciatica (Site unspecified)
0.687 0.313 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.686 0.314 0.000
S70-S79 Injuries to the hip and thigh
0.686 0.314 0.000
N18.4 Chronic kidney disease, stage 4
0.685 0.315 0.000
M54.57 Low back pain (Lumbosacral region)
0.685 0.315 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.684 0.316 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.684 0.316 0.000
N86 Erosion and ectropion of cervix uteri
0.684 0.316 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.684 0.316 0.000
J09-J18 Influenza and pneumonia
0.683 0.317 0.000
J34 Other disorders of nose and nasal sinuses
0.682 0.318 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.681 0.319 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.681 0.319 0.000
N97.9 Female infertility, unspecified
0.680 0.319 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.680 0.319 0.000
L81.4 Other melanin hyperpigmentation
0.680 0.320 0.000
M54.55 Low back pain (Thoracolumbar region)
0.680 0.320 0.000
M54.54 Low back pain-Thoracic
0.680 0.320 0.000
M54.53 Low back pain-Cervicothoracic
0.680 0.320 0.000
M54.52 Low back pain-Cervical
0.680 0.320 0.000
M54.51 Low back pain-Occipit-atl-axl
0.680 0.320 0.000
M54.50 Low back pain (Multiple sites in spine)
0.680 0.320 0.000
D62 Acute posthaemorrhagic anaemia
0.680 0.320 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.679 0.321 0.000
N13.6 Pyonephrosis
0.679 0.321 0.000
T51 Toxic effect of alcohol
0.679 0.321 0.000
M54.36 Sciatica (Lumbar region)
0.678 0.322 0.000
C44.1 Skin of eyelid, including canthus
0.678 0.322 0.000
V10-V19 Pedal cyclist injured in transport accident
0.677 0.323 0.000
T90 Sequelae of injuries of head
0.677 0.323 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.677 0.323 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
M20.3 Other deformity of hallux (acquired)
0.676 0.323 0.000
M20.0 Deformity of finger(s)
0.676 0.323 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.676 0.324 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.676 0.324 0.000
M49 Spondylopathies in diseases classified elsewhere
0.676 0.324 0.000
D50.1 Sideropenic dysphagia
0.675 0.325 0.000
C15-C26 Malignant neoplasms of digestive organs
0.675 0.325 0.000
L60 Nail disorders
0.674 0.326 0.000
A41 Other septicaemia
0.674 0.326 0.000
M10.9 Gout, unspecified
0.673 0.326 0.000
I67.9 Cerebrovascular disease, unspecified
0.673 0.327 0.000
C44.2 Skin of ear and external auricular canal
0.673 0.327 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.673 0.327 0.000
C01 Malignant neoplasm of base of tongue
0.673 0.327 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.672 0.328 0.000
N06 Isolated proteinuria with specified morphological lesion
0.672 0.328 0.000
N05 Unspecified nephritic syndrome
0.672 0.328 0.000
N04 Nephrotic syndrome
0.672 0.328 0.000
N01 Rapidly progressive nephritic syndrome
0.672 0.328 0.000
N00 Acute nephritic syndrome
0.672 0.328 0.000
I62 Other nontraumatic intracranial haemorrhage
0.672 0.328 0.000
I00-I02 Acute rheumatic fever
0.671 0.328 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.671 0.329 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.671 0.329 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.671 0.329 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.671 0.329 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.671 0.329 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.671 0.329 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.671 0.329 0.000
D64.8 Other specified anaemias
0.669 0.331 0.000
D64.4 Congenital dyserythropoietic anaemia
0.669 0.331 0.000
D64.3 Other sideroblastic anaemias
0.669 0.331 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.669 0.331 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.669 0.331 0.000
D64.0 Hereditary sideroblastic anaemia
0.669 0.331 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.668 0.332 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.668 0.332 0.000
L94 Other localised connective tissue disorders
0.668 0.332 0.000
L93 Lupus erythematosus
0.668 0.332 0.000
L87 Transepidermal elimination disorders
0.668 0.332 0.000
L88 Pyoderma gangrenosum
0.668 0.332 0.000
L86 Keratoderma in diseases classified elsewhere
0.668 0.332 0.000
L83 Acanthosis nigricans
0.668 0.332 0.000
L80 Vitiligo
0.668 0.332 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.668 0.332 0.000
J42 Unspecified chronic bronchitis
0.668 0.332 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.668 0.332 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.668 0.332 0.000
J60-J70 Lung diseases due to external agents
0.666 0.334 0.000
H93 Other disorders of ear, not elsewhere classified
0.666 0.334 0.000
I61 Intracerebral haemorrhage
0.666 0.334 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.666 0.334 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.666 0.334 0.000
L53 Other erythematous conditions
0.665 0.335 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
J37 Chronic laryngitis and laryngotracheitis
0.665 0.335 0.000
N18.5 Chronic kidney disease, stage 5
0.665 0.335 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.665 0.335 0.000
G70-G73 Diseases of myoneural junction and muscle
0.664 0.336 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
T93.2 Sequelae of other fractures of lower limb
0.662 0.338 0.000
L91 Hypertrophic disorders of skin
0.662 0.338 0.000
V80-V89 Other land transport accidents
0.662 0.338 0.000
H90 Conductive and sensorineural hearing loss
0.662 0.338 0.000
H91 Other hearing loss
0.661 0.339 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.661 0.339 0.000
N72 Inflammatory disease of cervix uteri
0.660 0.339 0.000
I67.1 Cerebral aneurysm, nonruptured
0.660 0.340 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.660 0.340 0.000
N88.2 Stricture and stenosis of cervix uteri
0.659 0.340 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.659 0.340 0.000
N48 Other disorders of penis
0.659 0.341 0.000
M54.22 Cervicalgia (Cervical region)
0.659 0.341 0.000
I05 Rheumatic mitral valve diseases
0.659 0.341 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.659 0.341 0.000
M25.47 Effusion of joint (Ankle and foot)
0.658 0.341 0.000
D27 Benign neoplasm of ovary
0.659 0.341 0.000
J43.9 Emphysema, unspecified
0.657 0.343 0.000
T92 Sequelae of injuries of upper limb
0.657 0.343 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.656 0.344 0.000
J30 Vasomotor and allergic rhinitis
0.655 0.345 0.000
M23.5 Chronic instability of knee
0.655 0.345 0.000
M25.9 Joint disorder, unspecified
0.655 0.345 0.000
M25.3 Other instability of joint
0.655 0.345 0.000
M25.2 Flail joint
0.655 0.345 0.000
M25.1 Fistula of joint
0.655 0.345 0.000
M25.0 Haemarthrosis
0.655 0.345 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.654 0.346 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.653 0.347 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.653 0.347 0.000
I67.5 Moyamoya disease
0.653 0.347 0.000
I67.4 Hypertensive encephalopathy
0.653 0.347 0.000
I67.3 Progressive vascular leukoencephalopathy
0.653 0.347 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.653 0.347 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.653 0.347 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.652 0.348 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.652 0.348 0.000
T17 Foreign body in respiratory tract
0.651 0.348 0.000
N17 Acute renal failure
0.651 0.349 0.000
L73 Other follicular disorders
0.651 0.349 0.000
U88 Agent resistant to multiple antibiotics
0.651 0.349 0.000
G57 Mononeuropathies of lower limb
0.651 0.349 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.651 0.349 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.651 0.349 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.650 0.349 0.000
H74 Other disorders of middle ear and mastoid
0.650 0.350 0.000
N03.8 Other
0.649 0.350 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.649 0.350 0.000
N03.6 Dense deposit disease
0.649 0.350 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.649 0.350 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.649 0.350 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.649 0.350 0.000
N03.2 Diffuse membranous glomerulonephritis
0.649 0.350 0.000
N03.1 Focal and segmental glomerular lesions
0.649 0.350 0.000
N03.0 Minor glomerular abnormality
0.649 0.350 0.000
M20.4 Other hammer toe(s) (acquired)
0.649 0.351 0.000
J33.0 Polyp of nasal cavity
0.648 0.351 0.000
T43.2 Other and unspecified antidepressants
0.648 0.352 0.000
B25-B34 Other viral diseases
0.647 0.353 0.000
C54 Malignant neoplasm of corpus uteri
0.646 0.354 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.645 0.355 0.000
M48.06 Spinal stenosis (Lumbar region)
0.644 0.356 0.000
J45.8 Mixed asthma
0.644 0.356 0.000
J45.1 Nonallergic asthma
0.644 0.356 0.000
Y40 Systemic antibiotics
0.644 0.356 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.644 0.356 0.000
G93 Other disorders of brain
0.642 0.358 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.641 0.358 0.000
M80 Osteoporosis with pathological fracture
0.641 0.359 0.000
I15 Secondary hypertension
0.641 0.359 0.000
I13 Hypertensive heart and renal disease
0.641 0.359 0.000
I11 Hypertensive heart disease
0.641 0.359 0.000
G81 Hemiplegia
0.641 0.359 0.000
N18.8 Other chronic renal failure
0.640 0.359 0.000
N18.1 Chronic kidney disease, stage 1
0.640 0.359 0.000
L20-L30 Dermatitis and eczema
0.640 0.360 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.640 0.360 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.640 0.360 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.640 0.360 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.640 0.360 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.640 0.360 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.640 0.360 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.640 0.360 0.000
F11 Mental and behavioural disorders due to use of opioids
0.640 0.360 0.000
T98 Sequelae of other and unspecified effects of external causes
0.639 0.361 0.000
T95 Sequelae of burns, corrosions and frostbite
0.639 0.361 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.639 0.361 0.000
T91 Sequelae of injuries of neck and trunk
0.639 0.361 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.639 0.361 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.639 0.361 0.000
M34.9 Systemic sclerosis, unspecified
0.638 0.362 0.000
N30 Cystitis
0.638 0.362 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.637 0.363 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.637 0.363 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.637 0.363 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.637 0.363 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.637 0.363 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.637 0.363 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.637 0.363 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.637 0.363 0.000
T36 Poisoning by systemic antibiotics
0.637 0.363 0.000
L40 Psoriasis
0.637 0.363 0.000
U89 Agent resistant to other and unspecified antibiotics
0.636 0.364 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.636 0.364 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.635 0.365 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.635 0.365 0.000
C77.4 Inguinal and lower limb lymph nodes
0.633 0.367 0.000
T63 Toxic effect of contact with venomous animals
0.632 0.367 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.632 0.368 0.000
M47.8 Other spondylosis
0.632 0.368 0.000
D51 Vitamin B12 deficiency anaemia
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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