TreeWAS – Variant ID: rs7860634

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.095	0.905	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.963	0.037
S93.0 Dislocation of ankle joint	0.000	0.987	0.013
S93.1 Dislocation of toe(s)	0.000	0.987	0.013
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.988	0.012
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.012	0.988	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.012	0.988	0.000
C85.1 B-cell lymphoma, unspecified	0.012	0.988	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.011	0.989	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.989	0.011
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.990	0.010
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.009	0.991	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.991	0.009
S93.4 Sprain and strain of ankle	0.000	0.991	0.009
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.991	0.009
S93.5 Sprain and strain of toe(s)	0.000	0.991	0.009
C85.0 Lymphosarcoma	0.009	0.991	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.991	0.009
R22.1 Localised swelling, mass and lump, neck	0.000	0.992	0.008
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.993	0.007
R22.0 Localised swelling, mass and lump, head	0.000	0.993	0.007
O82.0 Delivery by elective Caesarean section	0.000	0.993	0.007
S93.40 Sprain of unspecified ligament of ankle	0.000	0.993	0.007
E05 Thyrotoxicosis [hyperthyroidism]	0.007	0.993	0.000
Z99.3 Dependence on wheelchair	0.007	0.993	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.006	0.994	0.000
J32.2 Chronic ethmoidal sinusitis	0.006	0.994	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.994	0.006
Z36.9 Antenatal screening, unspecified	0.000	0.994	0.006
M19.93 Arthrosis, unspecified (Forearm)	0.006	0.994	0.000
M06.9 Rheumatoid arthritis, unspecified	0.005	0.995	0.000
F31.9 Bipolar affective disorder, unspecified	0.005	0.995	0.000
E05.5 Thyroid crisis or storm	0.005	0.995	0.000
E05.4 Thyrotoxicosis factitia	0.005	0.995	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.005	0.995	0.000
O82 Single delivery by Caesarean section	0.000	0.995	0.005
M06.98 Rheumatoid arthritis, unspecified (Other)	0.005	0.995	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.005	0.995	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.995	0.005
H72.0 Central perforation of tympanic membrane	0.000	0.995	0.005
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.004	0.995	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.995	0.005
M75.5 Bursitis of shoulder	0.000	0.995	0.005
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.996	0.004
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.996	0.004
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.004	0.996	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.996	0.004
J92.9 Pleural plaque without asbestos	0.004	0.996	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.996	0.004
Z43.3 Attention to colostomy	0.004	0.996	0.000
M06 Other rheumatoid arthritis	0.004	0.996	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.996	0.004
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.000	0.996	0.004
O82.8 Other single delivery by Caesarean section	0.000	0.996	0.004
O82.2 Delivery by Caesarean hysterectomy	0.000	0.996	0.004
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.996	0.004
E05.8 Other thyrotoxicosis	0.004	0.996	0.000
I61 Intracerebral haemorrhage	0.000	0.996	0.004
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.996	0.004
J60-J70 Lung diseases due to external agents	0.004	0.996	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.000	0.996	0.004
L20.9 Atopic dermatitis, unspecified	0.004	0.996	0.000
M06.4 Inflammatory polyarthropathy	0.004	0.996	0.000
Q05.9 Spina bifida, unspecified	0.000	0.996	0.004
R84.5 Abnormal microbiological findings	0.004	0.996	0.000
M06.3 Rheumatoid nodule	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.996	0.004
J69 Pneumonitis due to solids and liquids	0.003	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.003	0.997	0.000
J70 Respiratory conditions due to other external agents	0.003	0.997	0.000
K06.1 Gingival enlargement	0.000	0.997	0.003
J62 Pneumoconiosis due to dust containing silica	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.003
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.997	0.003
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
J69.0 Pneumonitis due to food and vomit	0.003	0.997	0.000
M06.1 Adult-onset Still's disease	0.003	0.997	0.000
J62.8 Pneumoconiosis due to other dust containing silica	0.003	0.997	0.000
J70.1 Chronic and other pulmonary manifestations due to radiation	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
M06.2 Rheumatoid bursitis	0.003	0.997	0.000
M06.8 Other specified rheumatoid arthritis	0.003	0.997	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.003	0.997	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.000	0.997	0.003
J64 Unspecified pneumoconiosis	0.003	0.997	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.003	0.997	0.000
R79.0 Abnormal level of blood mineral	0.000	0.997	0.003
J67 Hypersensitivity pneumonitis due to organic dust	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.003	0.997	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.003	0.997	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
R86.7 Abnormal histological findings	0.003	0.997	0.000
J69.8 Pneumonitis due to other solids and liquids	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.000	0.997	0.003
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.003	0.997	0.000
J66 Airway disease due to specific organic dust	0.003	0.997	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.003	0.997	0.000
J65 Pneumoconiosis associated with tuberculosis	0.003	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.997	0.003
E10.7 With multiple complications	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.003	0.997	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.003	0.997	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.003	0.997	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.003	0.997	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.003	0.997	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.003	0.997	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.997	0.003
R86 Abnormal findings in specimens from male genital organs	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
J70.4 Drug-induced interstitial lung disorder, unspecified	0.003	0.997	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.997	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.997	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.997	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.997	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.997	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.997	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.997	0.003
S90.1 Contusion of toe(s) without damage to nail	0.000	0.997	0.003
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.997	0.003
J69.1 Pneumonitis due to oils and essences	0.003	0.997	0.000
L89 Decubitus ulcer	0.000	0.997	0.003
I61.8 Other intracerebral haemorrhage	0.000	0.997	0.003
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.003	0.997	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.000	0.997	0.003
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
J70.9 Respiratory conditions due to unspecified external agent	0.003	0.997	0.000
J70.8 Respiratory conditions due to other specified external agents	0.003	0.997	0.000
J70.3 Chronic drug-induced interstitial lung disorders	0.003	0.997	0.000
J70.2 Acute drug-induced interstitial lung disorders	0.003	0.997	0.000
R80 Isolated proteinuria	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.003	0.997	0.000
J62.0 Pneumoconiosis due to talc dust	0.003	0.997	0.000
J60 Coalworker's pneumoconiosis	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.997	0.003
J42 Unspecified chronic bronchitis	0.003	0.997	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.003	0.997	0.000
R85.5 Abnormal microbiological findings	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.000	0.997	0.003
C17.0 Duodenum	0.003	0.997	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.002
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.997	0.000
M06.18 Adult-onset Still's disease (Other)	0.002	0.997	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.002	0.997	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.002	0.997	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.002	0.997	0.000
M06.14 Adult-onset Still's disease (Hand)	0.002	0.997	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.002	0.997	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.002	0.997	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.002	0.997	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
J70.0 Acute pulmonary manifestations due to radiation	0.002	0.997	0.000
Z36 Antenatal screening	0.000	0.997	0.003
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.997	0.000
C71.9 Brain, unspecified	0.000	0.997	0.003
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.997	0.003
M94.26 Chondromalacia (Lower leg)	0.003	0.997	0.000
S82.6 Fracture of lateral malleolus	0.000	0.997	0.003
M06.29 Rheumatoid bursitis (Site unspecified)	0.002	0.997	0.000
M06.28 Rheumatoid bursitis (Other)	0.002	0.997	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.002	0.997	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.002	0.997	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.002	0.997	0.000
M06.24 Rheumatoid bursitis (Hand)	0.002	0.997	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.002	0.997	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.002	0.997	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.002	0.997	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.002	0.997	0.000
K06.0 Gingival recession	0.000	0.997	0.002
R84.6 Abnormal cytological findings	0.002	0.997	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.002	0.997	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.002	0.997	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
C67.3 Anterior wall of bladder	0.000	0.997	0.003
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.003	0.997	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.997	0.002
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.002
J32 Chronic sinusitis	0.003	0.997	0.000
R86.9 Unspecified abnormal finding	0.002	0.997	0.000
R86.8 Other abnormal findings	0.002	0.997	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
J32.8 Other chronic sinusitis	0.002	0.998	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.002	0.998	0.000
J67.7 Air-conditioner and humidifier lung	0.002	0.998	0.000
J67.6 Maple-bark-stripper's lung	0.002	0.998	0.000
J67.5 Mushroom-worker's lung	0.002	0.998	0.000
J67.4 Maltworker's lung	0.002	0.998	0.000
J67.3 Suberosis	0.002	0.998	0.000
J67.1 Bagassosis	0.002	0.998	0.000
J67.0 Farmer's lung	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.000	0.998	0.002
C17.9 Small intestine, unspecified	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.002	0.998	0.000
G45.4 Transient global amnesia	0.002	0.998	0.000
R84.9 Unspecified abnormal finding	0.002	0.998	0.000
R84.8 Other abnormal findings	0.002	0.998	0.000
R84.4 Abnormal immunological findings	0.002	0.998	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R84.1 Abnormal level of hormones	0.002	0.998	0.000
R84.0 Abnormal level of enzymes	0.002	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.002	0.998	0.000
J63.5 Stannosis	0.002	0.998	0.000
J63.4 Siderosis	0.002	0.998	0.000
J63.3 Graphite fibrosis (of lung)	0.002	0.998	0.000
J63.2 Berylliosis	0.002	0.998	0.000
J63.1 Bauxite fibrosis (of lung)	0.002	0.998	0.000
J63.0 Aluminosis (of lung)	0.002	0.998	0.000
J66.8 Airway disease due to other specific organic dusts	0.002	0.998	0.000
J66.2 Cannabinosis	0.002	0.998	0.000
J66.1 Flax-dresser's disease	0.002	0.998	0.000
J66.0 Byssinosis	0.002	0.998	0.000
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.002	0.998	0.000
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.002	0.998	0.000
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.002	0.998	0.000
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.002	0.998	0.000
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.002	0.998	0.000
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.002	0.998	0.000
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.002	0.998	0.000
R86.5 Abnormal microbiological findings	0.002	0.998	0.000
L20 Atopic dermatitis	0.002	0.998	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.002	0.998	0.000
L20.8 Other atopic dermatitis	0.002	0.998	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.002	0.998	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.002	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.002	0.998	0.000
R85.8 Other abnormal findings	0.002	0.998	0.000
R86.4 Abnormal immunological findings	0.002	0.998	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R86.1 Abnormal level of hormones	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
R84.7 Abnormal histological findings	0.002	0.998	0.000
R86.6 Abnormal cytological findings	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
J67.2 Bird fancier's lung	0.002	0.998	0.000
R86.0 Abnormal level of enzymes	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
Z99.1 Dependence on respirator	0.002	0.998	0.000
R85.9 Unspecified abnormal finding	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
H02.5 Other disorders affecting eyelid function	0.002	0.998	0.000
C17 Malignant neoplasm of small intestine	0.002	0.998	0.000
E10.6 With other specified complications	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
R85.6 Abnormal cytological findings	0.002	0.998	0.000
R85.4 Abnormal immunological findings	0.002	0.998	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R85.1 Abnormal level of hormones	0.002	0.998	0.000
R85.0 Abnormal level of enzymes	0.002	0.998	0.000
S90.0 Contusion of ankle	0.000	0.998	0.002
Z36.5 Antenatal screening for isoimmunisation	0.000	0.998	0.002
S82.61 Fracture of lateral malleolus (open)	0.000	0.998	0.002
E10.2 With renal complications	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
R89.4 Abnormal immunological findings	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.998	0.002
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
C17.2 Ileum	0.002	0.998	0.000
R89.7 Abnormal histological findings	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
R89.0 Abnormal level of enzymes	0.002	0.998	0.000
E10.9 Without complications	0.002	0.998	0.000
E10.0 With coma	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.000	0.998	0.002
R83 Abnormal findings in cerebrospinal fluid	0.002	0.998	0.000
O86.4 Pyrexia of unknown origin following delivery	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
Z99.9 Dependence on unspecified enabling machine and device	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.002
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.002
S98.1 Traumatic amputation of one toe	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.998	0.002
Q05 Spina bifida	0.000	0.998	0.002
L20.0 Besnier's prurigo	0.002	0.998	0.000
R89.5 Abnormal microbiological findings	0.002	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.998	0.001
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
R89.8 Other abnormal findings	0.002	0.998	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R89.1 Abnormal level of hormones	0.002	0.998	0.000
R89.9 Unspecified abnormal finding	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.998	0.002
W19.4 Street and highway	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.998	0.002
C17.1 Jejunum	0.002	0.998	0.000
L91.8 Other hypertrophic disorders of skin	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
R89.6 Abnormal cytological findings	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
Z99.4 Dependence on artificial heart	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
M94.2 Chondromalacia	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.002	0.998	0.000
C17.3 Meckel's diverticulum	0.002	0.998	0.000
J32.1 Chronic frontal sinusitis	0.002	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
R83.8 Other abnormal findings	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
G35 Multiple sclerosis	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.001
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.998	0.002
F31 Bipolar affective disorder	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.002	0.998	0.000
R83.9 Unspecified abnormal finding	0.002	0.998	0.000
R83.7 Abnormal histological findings	0.002	0.998	0.000
R83.6 Abnormal cytological findings	0.002	0.998	0.000
R83.4 Abnormal immunological findings	0.002	0.998	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R83.1 Abnormal level of hormones	0.002	0.998	0.000
R83.0 Abnormal level of enzymes	0.002	0.998	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
T14.9 Injury, unspecified	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.000	0.998	0.002
Q05.6 Thoracic spina bifida without hydrocephalus	0.000	0.998	0.002
Q05.5 Cervical spina bifida without hydrocephalus	0.000	0.998	0.002
Q05.4 Unspecified spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.3 Sacral spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.2 Lumbar spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.1 Thoracic spina bifida with hydrocephalus	0.000	0.998	0.002
Q05.0 Cervical spina bifida with hydrocephalus	0.000	0.998	0.002
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.998	0.002
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.998	0.002
Y79.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.000	0.998	0.002
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.998	0.002
Z99.0 Dependence on aspirator	0.001	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.000	0.998	0.002
J32.4 Chronic pansinusitis	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.001	0.998	0.000
M94.28 Chondromalacia (Other)	0.001	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.001	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.001	0.998	0.000
M94.24 Chondromalacia (Hand)	0.001	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.001	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.001	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.001	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.001	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.998	0.002
R83.5 Abnormal microbiological findings	0.001	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.998	0.002
V28.5 Passenger injured in traffic accident	0.002	0.998	0.000
M11 Other crystal arthropathies	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.998	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.002
S21.2 Open wound of back wall of thorax	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.001	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.001
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
M11.9 Crystal arthropathy, unspecified	0.001	0.998	0.000
T14 Injury of unspecified body region	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.998	0.001
R43.0 Anosmia	0.001	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.001
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.998	0.001
M65.34 Trigger finger-Hand	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.998	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.001	0.998	0.000
G61.1 Serum neuropathy	0.001	0.998	0.000
L71.9 Rosacea, unspecified	0.002	0.998	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.001	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.001
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.001
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.000	0.998	0.001
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.999	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.999	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.999	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.999	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.999	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.999	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.999	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.001	0.999	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.999	0.001
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.999	0.001
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.999	0.001
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.999	0.001
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.999	0.000
Z50.8 Care involving use of rehabilitation procedures	0.001	0.999	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
M11.8 Other specified crystal arthropathies	0.001	0.999	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.999	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.999	0.000
A49.8 Other bacterial infections of unspecified site	0.001	0.999	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.999	0.001
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.001	0.999	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.999	0.001
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
H36.0 Diabetic retinopathy	0.001	0.999	0.000
M05.8 Other seropositive rheumatoid arthritis	0.001	0.999	0.000
M05.1 Rheumatoid lung disease	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.001	0.999	0.000
M11.1 Familial chondrocalcinosis	0.001	0.999	0.000
M11.0 Hydroxyapatite deposition disease	0.001	0.999	0.000
X51.9 Unspecified place	0.000	0.999	0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.999	0.001
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.001	0.999	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.999	0.000
M05.0 Felty's syndrome	0.001	0.999	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.999	0.001
S92.31 Fracture of metatarsal bone (open)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations